| Year |
Citation |
Score |
| 2020 |
Hojo-Souza NS, de Azevedo PO, de Castro JT, Teixeira-Carvalho A, Lieberman J, Junqueira C, Gazzinelli RT. Contributions of IFN-γ and granulysin to the clearance of Plasmodium yoelii blood stage. Plos Pathogens. 16: e1008840. PMID 32913355 DOI: 10.1371/Journal.Ppat.1008840 |
0.374 |
|
| 2020 |
Crespo ÂC, Mulik S, Dotiwala F, Ansara JA, Sen Santara S, Ingersoll K, Ovies C, Junqueira C, Tilburgs T, Strominger JL, Lieberman J. Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts. Cell. PMID 32822574 DOI: 10.1016/J.Cell.2020.07.019 |
0.367 |
|
| 2020 |
Hu JJ, Liu X, Xia S, Zhang Z, Zhang Y, Zhao J, Ruan J, Luo X, Lou X, Bai Y, Wang J, Hollingsworth LR, Magupalli VG, Zhao L, Luo HR, ... ... Lieberman J, et al. FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation. Nature Immunology. PMID 32367036 DOI: 10.1038/S41590-020-0669-6 |
0.309 |
|
| 2020 |
Zhang Z, Zhang Y, Xia S, Kong Q, Li S, Liu X, Junqueira C, Meza-Sosa KF, Mok TMY, Ansara J, Sengupta S, Yao Y, Wu H, Lieberman J. Gasdermin E suppresses tumour growth by activating anti-tumour immunity. Nature. 579: 415-420. PMID 32188940 DOI: 10.1038/S41586-020-2071-9 |
0.38 |
|
| 2020 |
Liu X, Lieberman J. Knocking 'em Dead: Pore-Forming Proteins in Immune Defense. Annual Review of Immunology. PMID 32004099 DOI: 10.1146/Annurev-Immunol-111319-023800 |
0.311 |
|
| 2020 |
Zhang Z, Zhang Y, Xia S, Kong Q, Li S, Liu X, Junqueira C, Ansara J, Sengupta S, Yao Y, Wu H, Lieberman J. Abstract B58: Gasdermin E suppresses tumor growth by activating antitumor immunity Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm19-B58 |
0.382 |
|
| 2019 |
Dotiwala F, Lieberman J. Granulysin: killer lymphocyte safeguard against microbes. Current Opinion in Immunology. 60: 19-29. PMID 31112765 DOI: 10.1016/J.Coi.2019.04.013 |
0.409 |
|
| 2019 |
Vu LT, Peng B, Zhang DX, Ma V, Mathey-Andrews CA, Lam CK, Kiomourtzis T, Jin J, McReynolds L, Huang L, Grimson A, Cho WC, Lieberman J, Le MT. Tumor-secreted extracellular vesicles promote the activation of cancer-associated fibroblasts via the transfer of microRNA-125b. Journal of Extracellular Vesicles. 8: 1599680. PMID 31044053 DOI: 10.1080/20013078.2019.1599680 |
0.36 |
|
| 2019 |
Zhang Y, Lieberman J. Abstract B057: Enhancing immunotherapy for triple-negative and HER2+ breast cancer using EpCAM aptamer-siRNA mediated gene knockdown Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B057 |
0.401 |
|
| 2019 |
Hu J, Liu X, Zhao J, Xia S, Ruan J, Luo X, Kim J, Lieberman J, Wu H. Abstract A132: Identification of pyroptosis inhibitors that target a reactive cysteine in gasdermin D Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A132 |
0.322 |
|
| 2019 |
Vu LT, Peng B, Zhang DX, Ma V, Grimson A, Cho WC, Lieberman J, Le MT. Abstract 2034: Activation of cancer-associated fibroblasts via the transfer of miR-125b containing extracellular vesicles from tumor cells Cancer Research. 79: 2034-2034. DOI: 10.1158/1538-7445.Am2019-2034 |
0.352 |
|
| 2019 |
Zhang Z, Zhang Y, Xia S, Kong Q, Li S, Liu X, Junqueira C, Ansara J, Sengupta S, Yao Y, Wu H, Lieberman J. Abstract A022: Gasdermin E suppresses tumor growth by activating antitumor immunity Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-A022 |
0.351 |
|
| 2018 |
Trifonova RT, Bollman B, Barteneva NS, Lieberman J. Myeloid Cells in Intact Human Cervical Explants Capture HIV and Can Transmit It to CD4 T Cells. Frontiers in Immunology. 9: 2719. PMID 30532754 DOI: 10.3389/Fimmu.2018.02719 |
0.465 |
|
| 2018 |
Junqueira C, Barbosa CRR, Costa PAC, Teixeira-Carvalho A, Castro G, Sen Santara S, Barbosa RP, Dotiwala F, Pereira DB, Antonelli LR, Lieberman J, Gazzinelli RT. Cytotoxic CD8 T cells recognize and kill Plasmodium vivax-infected reticulocytes. Nature Medicine. PMID 30038217 DOI: 10.1038/S41591-018-0117-4 |
0.404 |
|
| 2018 |
Meyer SE, Muench DE, Rogers AM, Newkold TJ, Orr E, O'Brien E, Perentesis JP, Doench JG, Lal A, Morris PJ, Thomas CJ, Lieberman J, McGlinn E, Aronow BJ, Salomonis N, et al. miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential. The Journal of Experimental Medicine. PMID 29997117 DOI: 10.1084/Jem.20171312 |
0.312 |
|
| 2018 |
Liu X, Fu R, Pan Y, Meza-Sosa KF, Zhang Z, Lieberman J. PNPT1 Release from Mitochondria during Apoptosis Triggers Decay of Poly(A) RNAs. Cell. PMID 29779946 DOI: 10.1016/J.Cell.2018.04.017 |
0.325 |
|
| 2018 |
Clayton KL, Collins DR, Lengieza J, Ghebremichael M, Dotiwala F, Lieberman J, Walker BD. Resistance of HIV-infected macrophages to CD8 T lymphocyte-mediated killing drives activation of the immune system. Nature Immunology. 19: 475-486. PMID 29670239 DOI: 10.1038/S41590-018-0085-3 |
0.469 |
|
| 2018 |
Kedmi R, Veiga N, Ramishetti S, Goldsmith M, Rosenblum D, Dammes N, Hazan-Halevy I, Nahary L, Leviatan-Ben-Arye S, Harlev M, Behlke M, Benhar I, Lieberman J, Peer D. A modular platform for targeted RNAi therapeutics. Nature Nanotechnology. PMID 29379205 DOI: 10.1038/S41565-017-0043-5 |
0.334 |
|
| 2017 |
Dotiwala F, Sen Santara S, Binker-Cosen AA, Li B, Chandrasekaran S, Lieberman J. Granzyme B Disrupts Central Metabolism and Protein Synthesis in Bacteria to Promote an Immune Cell Death Program. Cell. PMID 29107333 DOI: 10.1016/J.Cell.2017.10.004 |
0.334 |
|
| 2017 |
Sula Karreci E, Eskandari SK, Dotiwala F, Routray SK, Kurdi AT, Assaker JP, Luckyanchykov P, Mihali AB, Maarouf O, Borges TJ, Alkhudhayri A, Patel KR, Radwan A, Ghobrial I, McGrath M, ... ... Lieberman J, et al. Human regulatory T cells undergo self-inflicted damage via granzyme pathways upon activation. Jci Insight. 2. PMID 29093262 DOI: 10.1172/Jci.Insight.91599 |
0.384 |
|
| 2017 |
Chan S, Sridhar P, Kirchner R, Lock YJ, Herbert Z, Buonamici S, Smith P, Lieberman J, Petrocca F. Basal-A Triple Negative Breast Cancer Cells Selectively Rely on RNA Splicing for Survival. Molecular Cancer Therapeutics. PMID 28878028 DOI: 10.1158/1535-7163.Mct-17-0461 |
0.342 |
|
| 2017 |
Liu X, Lieberman J. A Mechanistic Understanding of Pyroptosis: The Fiery Death Triggered by Invasive Infection. Advances in Immunology. 135: 81-117. PMID 28826530 DOI: 10.1016/Bs.Ai.2017.02.002 |
0.375 |
|
| 2017 |
Deruaz M, Murooka TT, Ji S, Gavin MA, Vrbanac VD, Lieberman J, Tager AM, Mempel TR, Luster AD. Chemoattractant-mediated leukocyte trafficking enables HIV dissemination from the genital mucosa. Jci Insight. 2: e88533. PMID 28405607 DOI: 10.1172/Jci.Insight.88533 |
0.392 |
|
| 2017 |
Su S, Liao J, Liu J, Huang D, He C, Chen F, Yang L, Wu W, Chen J, Lin L, Zeng Y, Ouyang N, Cui X, Yao H, Su F, ... ... Lieberman J, et al. Blocking the recruitment of naive CD4(+) T cells reverses immunosuppression in breast cancer. Cell Research. PMID 28290464 DOI: 10.1038/Cr.2017.34 |
0.394 |
|
| 2017 |
Liu X, Lieberman J. How ICE lights the pyroptosis fire. Cell Death and Differentiation. PMID 28060375 DOI: 10.1038/Cdd.2016.157 |
0.364 |
|
| 2016 |
Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J. Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. Nature. 535: 153-158. PMID 27383986 DOI: 10.1038/Nature18629 |
0.362 |
|
| 2016 |
Wheeler LA, Trifonova RT, Vrbanac V, Barteneva NS, Liu X, Bollman B, Onofrey L, Mulik S, Ranjbar S, Luster AD, Tager AM, Lieberman J. TREX1 Knockdown Induces an Interferon Response to HIV that Delays Viral Infection in Humanized Mice. Cell Reports. PMID 27184854 DOI: 10.1016/J.Celrep.2016.04.048 |
0.765 |
|
| 2016 |
Boulias K, Lieberman J, Greer EL. An Epigenetic Clock Measures Accelerated Aging in Treated HIV Infection. Molecular Cell. 62: 153-5. PMID 27105110 DOI: 10.1016/J.Molcel.2016.04.008 |
0.357 |
|
| 2016 |
Basu R, Whitlock BM, Husson J, Le Floc'h A, Jin W, Oyler-Yaniv A, Dotiwala F, Giannone G, Hivroz C, Biais N, Lieberman J, Kam LC, Huse M. Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing. Cell. PMID 26924577 DOI: 10.1016/J.Cell.2016.01.021 |
0.361 |
|
| 2016 |
Dotiwala F, Mulik S, Polidoro RB, Ansara JA, Burleigh BA, Walch M, Gazzinelli RT, Lieberman J. Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites. Nature Medicine. 22: 210-6. PMID 26752517 DOI: 10.1038/Nm.4023 |
0.387 |
|
| 2016 |
Weinstein S, Toker IA, Emmanuel R, Ramishetti S, Hazan-Halevy I, Rosenblum D, Goldsmith M, Abraham A, Benjamini O, Bairey O, Raanani P, Nagler A, Lieberman J, Peer D. Harnessing RNAi-based nanomedicines for therapeutic gene silencing in B-cell malignancies. Proceedings of the National Academy of Sciences of the United States of America. 113: E16-22. PMID 26699502 DOI: 10.1073/Pnas.1519273113 |
0.386 |
|
| 2015 |
Walch M, Dotiwala F, Mulik S, Thiery J, Kirchhausen T, Clayberger C, Krensky AM, Martinvalet D, Lieberman J. Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes. Cell. 161: 1229. PMID 28910642 DOI: 10.1016/J.Cell.2015.05.021 |
0.377 |
|
| 2015 |
Wittrup A, Lieberman J. Knocking down disease: a progress report on siRNA therapeutics. Nature Reviews. Genetics. 16: 543-52. PMID 26281785 DOI: 10.1038/Nrg3978 |
0.307 |
|
| 2015 |
Gilboa-Geffen A, Hamar P, Le MT, Wheeler LA, Trifonova R, Petrocca F, Wittrup A, Lieberman J. Gene Knockdown by EpCAM Aptamer-siRNA Chimeras Suppresses Epithelial Breast Cancers and Their Tumor-Initiating Cells. Molecular Cancer Therapeutics. 14: 2279-91. PMID 26264278 DOI: 10.1158/1535-7163.Mct-15-0201-T |
0.757 |
|
| 2015 |
Wittrup A, Ai A, Liu X, Hamar P, Trifonova R, Charisse K, Manoharan M, Kirchhausen T, Lieberman J. Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown. Nature Biotechnology. PMID 26192320 DOI: 10.1038/Nbt.3298 |
0.306 |
|
| 2015 |
Lieberman J. Manipulating the in vivo immune response by targeted gene knockdown. Current Opinion in Immunology. 35: 63-72. PMID 26149459 DOI: 10.1016/J.Coi.2015.06.005 |
0.369 |
|
| 2015 |
Dotiwala F, Fellay I, Filgueira L, Martinvalet D, Lieberman J, Walch M. A High Yield and Cost-efficient Expression System of Human Granzymes in Mammalian Cells. Journal of Visualized Experiments : Jove. e52911. PMID 26132420 DOI: 10.3791/52911 |
0.403 |
|
| 2015 |
Thomas MP, Liu X, Whangbo J, McCrossan G, Sanborn KB, Basar E, Walch M, Lieberman J. Apoptosis Triggers Specific, Rapid, and Global mRNA Decay with 3' Uridylated Intermediates Degraded by DIS3L2. Cell Reports. 11: 1079-89. PMID 25959823 DOI: 10.1016/J.Celrep.2015.04.026 |
0.336 |
|
| 2015 |
Sharei A, Trifonova R, Jhunjhunwala S, Hartoularos GC, Eyerman AT, Lytton-Jean A, Angin M, Sharma S, Poceviciute R, Mao S, Heimann M, Liu S, Talkar T, Khan OF, Addo M, ... ... Lieberman J, et al. Ex vivo cytosolic delivery of functional macromolecules to immune cells. Plos One. 10: e0118803. PMID 25875117 DOI: 10.1371/Journal.Pone.0118803 |
0.399 |
|
| 2015 |
Luo ML, Gong C, Chen CH, Hu H, Huang P, Zheng M, Yao Y, Wei S, Wulf G, Lieberman J, Zhou XZ, Song E, Lu KP. The Rab2A GTPase promotes breast cancer stem cells and tumorigenesis via Erk signaling activation. Cell Reports. 11: 111-24. PMID 25818297 DOI: 10.1016/J.Celrep.2015.03.002 |
0.336 |
|
| 2015 |
Jacquemin G, Margiotta D, Kasahara A, Bassoy EY, Walch M, Thiery J, Lieberman J, Martinvalet D. Granzyme B-induced mitochondrial ROS are required for apoptosis. Cell Death and Differentiation. 22: 862-74. PMID 25361078 DOI: 10.1038/Cdd.2014.180 |
0.304 |
|
| 2015 |
Lieberman J, Le M. Abstract SY09-04: Cancer crosstalk: miR-200-containing extracellular vesicles promote breast cancer cell metastasis Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Sy09-04 |
0.332 |
|
| 2015 |
Gilboa-Geffen A, Hamar P, Wheeler LA, Trifonova R, Petrocca F, Wittrup A, Lieberman J. Abstract LB-299: Gene knockdown by EpCAM aptamer-siRNA chimeras suppresses epithelial breast cancers and their tumor-initiating cells Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-299 |
0.753 |
|
| 2014 |
Le MT, Hamar P, Guo C, Basar E, Perdigão-Henriques R, Balaj L, Lieberman J. miR-200-containing extracellular vesicles promote breast cancer cell metastasis. The Journal of Clinical Investigation. 124: 5109-28. PMID 25401471 DOI: 10.1172/Jci75695 |
0.333 |
|
| 2014 |
Walch M, Dotiwala F, Mulik S, Thiery J, Kirchhausen T, Clayberger C, Krensky AM, Martinvalet D, Lieberman J. Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes. Cell. 157: 1309-23. PMID 24906149 DOI: 10.1016/J.Cell.2014.03.062 |
0.358 |
|
| 2014 |
Thiery J, Lieberman J. Perforin: a key pore-forming protein for immune control of viruses and cancer. Sub-Cellular Biochemistry. 80: 197-220. PMID 24798013 DOI: 10.1007/978-94-017-8881-6_10 |
0.407 |
|
| 2014 |
Luo ML, Gong C, Chen CH, Lee DY, Hu H, Huang P, Yao Y, Guo W, Reinhardt F, Wulf G, Lieberman J, Zhou XZ, Song E, Lu KP. Prolyl isomerase Pin1 acts downstream of miR200c to promote cancer stem-like cell traits in breast cancer. Cancer Research. 74: 3603-16. PMID 24786790 DOI: 10.1158/0008-5472.Can-13-2785 |
0.357 |
|
| 2014 |
Thomas MP, Whangbo J, McCrossan G, Deutsch AJ, Martinod K, Walch M, Lieberman J. Leukocyte protease binding to nucleic acids promotes nuclear localization and cleavage of nucleic acid binding proteins. Journal of Immunology (Baltimore, Md. : 1950). 192: 5390-7. PMID 24771851 DOI: 10.4049/Jimmunol.1303296 |
0.352 |
|
| 2014 |
Trifonova RT, Lieberman J, van Baarle D. Distribution of immune cells in the human cervix and implications for HIV transmission. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 71: 252-64. PMID 24410939 DOI: 10.1111/Aji.12198 |
0.373 |
|
| 2014 |
Petrocca F, Altschuler G, Tan SM, Mendillo ML, Yan H, Jerry DJ, Kung AL, Hide W, Ince TA, Lieberman J. Abstract SY43-03: Screening for triple negative breast cancer vulnerabilities Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy43-03 |
0.338 |
|
| 2013 |
Huang L, Lieberman J. Production of highly potent recombinant siRNAs in Escherichia coli. Nature Protocols. 8: 2325-36. PMID 24177290 DOI: 10.1038/Nprot.2013.149 |
0.311 |
|
| 2013 |
Tuli A, Thiery J, James AM, Michelet X, Sharma M, Garg S, Sanborn KB, Orange JS, Lieberman J, Brenner MB. Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity. Molecular Biology of the Cell. 24: 3721-35. PMID 24088571 DOI: 10.1091/Mbc.E13-05-0259 |
0.373 |
|
| 2013 |
Petrocca F, Altschuler G, Tan SM, Mendillo ML, Yan H, Jerry DJ, Kung AL, Hide W, Ince TA, Lieberman J. A genome-wide siRNA screen identifies proteasome addiction as a vulnerability of basal-like triple-negative breast cancer cells. Cancer Cell. 24: 182-96. PMID 23948298 DOI: 10.1016/J.Ccr.2013.07.008 |
0.308 |
|
| 2013 |
Wheeler LA, Vrbanac V, Trifonova R, Brehm MA, Gilboa-Geffen A, Tanno S, Greiner DL, Luster AD, Tager AM, Lieberman J. Durable knockdown and protection from HIV transmission in humanized mice treated with gel-formulated CD4 aptamer-siRNA chimeras. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1378-89. PMID 23629001 DOI: 10.1038/Mt.2013.77 |
0.757 |
|
| 2013 |
Huang L, Jin J, Deighan P, Kiner E, McReynolds L, Lieberman J. Efficient and specific gene knockdown by small interfering RNAs produced in bacteria. Nature Biotechnology. 31: 350-6. PMID 23475073 DOI: 10.1038/Nbt.2537 |
0.336 |
|
| 2013 |
Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N. Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nature Immunology. 14: 179-85. PMID 23263557 DOI: 10.1038/Ni.2509 |
0.327 |
|
| 2013 |
Andrew RM, Aronow BJ, Komurov K, Lal A, Lieberman J, Grimes HL. Functional Screening Of Oncomir-196b-RISC Captured Targets Reveal Mir-Inhibition Of Tumor Suppressor Activity In MLL-AF9 Mediated Leukemogenesis Blood. 122: 475-475. DOI: 10.1182/Blood.V122.21.475.475 |
0.323 |
|
| 2013 |
Thomas M, McCrossan G, Deutsch A, Martinod K, Walch M, Lieberman J. Binding Of Immune Serine Proteases To Nucleic Acids Enhances Their Nuclear Localization and Promotes Their Cleavage Of Nucleic Acid-Binding Protein Substrates Blood. 122: 3471-3471. DOI: 10.1182/Blood.V122.21.3471.3471 |
0.369 |
|
| 2013 |
Gilboa-Geffen A, Wheeler LA, Wittrup A, Petrocca F, Lieberman J. Abstract CN01-02: Targeting basal-like TNBCs and epithelial tumor-initiating cells with aptamer-siRNA chimeras. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-Cn01-02 |
0.757 |
|
| 2012 |
Yan N, Lieberman J. SAMHD1 does it again, now in resting T cells. Nature Medicine. 18: 1611-2. PMID 23135508 DOI: 10.1038/Nm.2980 |
0.451 |
|
| 2012 |
Rajani DK, Walch M, Martinvalet D, Thomas MP, Lieberman J. Alterations in RNA processing during immune-mediated programmed cell death. Proceedings of the National Academy of Sciences of the United States of America. 109: 8688-93. PMID 22589304 DOI: 10.1073/Pnas.1201327109 |
0.383 |
|
| 2012 |
Yao YD, Sun TM, Huang SY, Dou S, Lin L, Chen JN, Ruan JB, Mao CQ, Yu FY, Zeng MS, Zang JY, Liu Q, Su FX, Zhang P, Lieberman J, et al. Targeted delivery of PLK1-siRNA by ScFv suppresses Her2+ breast cancer growth and metastasis. Science Translational Medicine. 4: 130ra48. PMID 22517885 DOI: 10.1126/Scitranslmed.3003601 |
0.334 |
|
| 2012 |
Yan N, Wheeler LA, Regalado-Magdos AD, Stiggelbout B, Lee-Kirsch MA, Lieberman J. 144 The Cytosolic Exonuclease TREX1 Digests HIV Reverse Transcripts to Avoid Triggering an Antiviral Interferon Response in T Cells and Macrophages Journal of Acquired Immune Deficiency Syndromes. 59: 60. DOI: 10.1097/01.Qai.0000413764.04308.82 |
0.775 |
|
| 2011 |
Le MT, Shyh-Chang N, Khaw SL, Chin L, Teh C, Tay J, O'Day E, Korzh V, Yang H, Lal A, Lieberman J, Lodish HF, Lim B. Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs. Plos Genetics. 7: e1002242. PMID 21935352 DOI: 10.1371/Journal.Pgen.1002242 |
0.305 |
|
| 2011 |
Lakhashe SK, Velu V, Sciaranghella G, Siddappa NB, Dipasquale JM, Hemashettar G, Yoon JK, Rasmussen RA, Yang F, Lee SJ, Montefiori DC, Novembre FJ, Villinger F, Amara RR, Kahn M, ... ... Lieberman J, et al. Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges. Vaccine. 29: 5611-22. PMID 21693155 DOI: 10.1016/J.Vaccine.2011.06.017 |
0.385 |
|
| 2011 |
Thiery J, Keefe D, Boulant S, Boucrot E, Walch M, Martinvalet D, Goping IS, Bleackley RC, Kirchhausen T, Lieberman J. Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells. Nature Immunology. 12: 770-7. PMID 21685908 DOI: 10.1038/Ni.2050 |
0.338 |
|
| 2011 |
Wheeler LA, Trifonova R, Vrbanac V, Basar E, McKernan S, Xu Z, Seung E, Deruaz M, Dudek T, Einarsson JI, Yang L, Allen TM, Luster AD, Tager AM, Dykxhoorn DM, ... Lieberman J, et al. Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras. The Journal of Clinical Investigation. 121: 2401-12. PMID 21576818 DOI: 10.1172/Jci45876 |
0.773 |
|
| 2011 |
Yan N, O'Day E, Wheeler LA, Engelman A, Lieberman J. HIV DNA is heavily uracilated, which protects it from autointegration. Proceedings of the National Academy of Sciences of the United States of America. 108: 9244-9. PMID 21576478 DOI: 10.1073/Pnas.1102943108 |
0.767 |
|
| 2011 |
Whitney JB, Mirshahidi S, Lim SY, Goins L, Ibegbu CC, Anderson DC, Raybourne RB, Frankel FR, Lieberman J, Ruprecht RM. Prior exposure to an attenuated Listeria vaccine does not reduce immunogenicity: pre-clinical assessment of the efficacy of a Listeria vaccine in the induction of immune responses against HIV. Journal of Immune Based Therapies and Vaccines. 9: 2. PMID 21244649 DOI: 10.1186/1476-8518-9-2 |
0.313 |
|
| 2011 |
Yan N, Lieberman J. Gaining a foothold: how HIV avoids innate immune recognition. Current Opinion in Immunology. 23: 21-8. PMID 21123040 DOI: 10.1016/J.Coi.2010.11.004 |
0.403 |
|
| 2011 |
Petrocca F, Lieberman J. Promise and challenge of RNA interference-based therapy for cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 747-54. PMID 21079135 DOI: 10.1200/Jco.2009.27.6287 |
0.344 |
|
| 2010 |
Yan N, Regalado-Magdos AD, Stiggelbout B, Lee-Kirsch MA, Lieberman J. The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1. Nature Immunology. 11: 1005-13. PMID 20871604 DOI: 10.1038/Ni.1941 |
0.371 |
|
| 2010 |
Lieberman J. Granzyme A activates another way to die. Immunological Reviews. 235: 93-104. PMID 20536557 DOI: 10.1111/J.0105-2896.2010.00902.X |
0.383 |
|
| 2010 |
Lieberman J. Anatomy of a murder: how cytotoxic T cells and NK cells are activated, develop, and eliminate their targets. Immunological Reviews. 235: 5-9. PMID 20536551 DOI: 10.1111/J.0105-2896.2010.00914.X |
0.421 |
|
| 2010 |
Thiery J, Walch M, Jensen DK, Martinvalet D, Lieberman J. Isolation of cytotoxic T cell and NK granules and purification of their effector proteins. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit3.37. PMID 20521234 DOI: 10.1002/0471143030.Cb0337S47 |
0.779 |
|
| 2010 |
Niland B, Miklossy G, Banki K, Biddison WE, Casciola-Rosen L, Rosen A, Martinvalet D, Lieberman J, Perl A. Cleavage of transaldolase by granzyme B causes the loss of enzymatic activity with retention of antigenicity for multiple sclerosis patients. Journal of Immunology (Baltimore, Md. : 1950). 184: 4025-32. PMID 20194725 DOI: 10.4049/Jimmunol.0804174 |
0.354 |
|
| 2010 |
Thiery J, Keefe D, Saffarian S, Martinvalet D, Walch M, Boucrot E, Kirchhausen T, Lieberman J. Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis. Blood. 115: 1582-93. PMID 20038786 DOI: 10.1182/Blood-2009-10-246116 |
0.314 |
|
| 2010 |
Lieberman J. Micromanipulating Hematological Malignancies and Other Cancers Blood. 116. DOI: 10.1182/Blood.V116.21.Sci-33.Sci-33 |
0.316 |
|
| 2010 |
Wheeler A, Lieberman J, Trifonova R, Basar E, Dykxhoorn D. Developing a Topical HIV Microbicide: CD4-targeting Aptamers Inhibit HIV Infection in Primary Cells in vitro and in Polarized Human Cervical Explants Clinical Immunology. 135: S96-S97. DOI: 10.1016/J.Clim.2010.03.290 |
0.408 |
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| 2009 |
Dykxhoorn DM, Wu Y, Xie H, Yu F, Lal A, Petrocca F, Martinvalet D, Song E, Lim B, Lieberman J. miR-200 enhances mouse breast cancer cell colonization to form distant metastases. Plos One. 4: e7181. PMID 19787069 DOI: 10.1371/Journal.Pone.0007181 |
0.367 |
|
| 2009 |
Lal A, Navarro F, Maher CA, Maliszewski LE, Yan N, O'Day E, Chowdhury D, Dykxhoorn DM, Tsai P, Hofmann O, Becker KG, Gorospe M, Hide W, Lieberman J. miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements. Molecular Cell. 35: 610-25. PMID 19748357 DOI: 10.1016/J.Molcel.2009.08.020 |
0.746 |
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| 2009 |
Ahmed F, Friend S, George TC, Barteneva N, Lieberman J. Numbers matter: quantitative and dynamic analysis of the formation of an immunological synapse using imaging flow cytometry. Journal of Immunological Methods. 347: 79-86. PMID 19524586 DOI: 10.1016/J.Jim.2009.05.014 |
0.337 |
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| 2009 |
Zhu P, Martinvalet D, Chowdhury D, Zhang D, Schlesinger A, Lieberman J. The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5'-diphosphate-ribose) polymerase-1. Blood. 114: 1205-16. PMID 19506301 DOI: 10.1182/Blood-2008-12-195768 |
0.772 |
|
| 2009 |
Lal A, Pan Y, Navarro F, Dykxhoorn DM, Moreau L, Meire E, Bentwich Z, Lieberman J, Chowdhury D. miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells. Nature Structural & Molecular Biology. 16: 492-8. PMID 19377482 DOI: 10.1038/Nsmb.1589 |
0.341 |
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| 2009 |
Yan N, Cherepanov P, Daigle JE, Engelman A, Lieberman J. The SET complex acts as a barrier to autointegration of HIV-1. Plos Pathogens. 5: e1000327. PMID 19266025 DOI: 10.1371/Journal.Ppat.1000327 |
0.363 |
|
| 2009 |
Wu Y, Navarro F, Lal A, Basar E, Pandey RK, Manoharan M, Feng Y, Lee SJ, Lieberman J, Palliser D. Durable protection from Herpes Simplex Virus-2 transmission following intravaginal application of siRNAs targeting both a viral and host gene. Cell Host & Microbe. 5: 84-94. PMID 19154990 DOI: 10.1016/J.Chom.2008.12.003 |
0.321 |
|
| 2009 |
Wheeler L, Basar E, McKernan S, Dykxhoorn D, Lieberman J. P19-22. CD4-targeted delivery of HIV and CCR5 siRNAs by aptamer-siRNA chimeras suppresses HIV infection in primary cells and in human cervical explants Retrovirology. 6: P342. DOI: 10.1186/1742-4690-6-S3-P342 |
0.785 |
|
| 2009 |
Martinvalet D, Walch M, Jensen DK, Thiery J, Lieberman J. Response: Granzyme A: cell death–inducing protease, proinflammatory agent, or both? Blood. 114: 3969-3970. DOI: 10.1182/Blood-2009-08-233577 |
0.777 |
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| 2009 |
Yan N, Cherepanov P, Daigle JE, Alan, Lieberman J. 158 The SET complex acts as a barrier to autointegration of HIV-1 Journal of Acquired Immune Deficiency Syndromes. 51: 1. DOI: 10.1097/01.Qai.0000351113.80299.B3 |
0.309 |
|
| 2009 |
Wheeler LA, Lieberman J. T.19.5. Synthesis of a Bifunctional Chimera: Discriminate Delivery of siRNA to CD4+Cells by Fusion to RNA-based Aptamers Clinical Immunology. 131. DOI: 10.1016/J.Clim.2009.03.160 |
0.759 |
|
| 2008 |
Shun MC, Botbol Y, Li X, Di Nunzio F, Daigle JE, Yan N, Lieberman J, Lavigne M, Engelman A. Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity. Journal of Virology. 82: 11555-67. PMID 18799576 DOI: 10.1128/Jvi.01561-08 |
0.319 |
|
| 2008 |
Chowdhury D, Xu X, Zhong X, Ahmed F, Zhong J, Liao J, Dykxhoorn DM, Weinstock DM, Pfeifer GP, Lieberman J. A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication. Molecular Cell. 31: 33-46. PMID 18614045 DOI: 10.1016/J.Molcel.2008.05.016 |
0.303 |
|
| 2008 |
Martinvalet D, Dykxhoorn DM, Ferrini R, Lieberman J. Granzyme A cleaves a mitochondrial complex I protein to initiate caspase-independent cell death. Cell. 133: 681-92. PMID 18485875 DOI: 10.1016/J.Cell.2008.03.032 |
0.347 |
|
| 2008 |
Dykxhoorn DM, Chowdhury D, Lieberman J. RNA interference and cancer: endogenous pathways and therapeutic approaches. Advances in Experimental Medicine and Biology. 615: 299-329. PMID 18437900 DOI: 10.1007/978-1-4020-6554-5_14 |
0.354 |
|
| 2008 |
Chowdhury D, Lieberman J. Death by a thousand cuts: granzyme pathways of programmed cell death. Annual Review of Immunology. 26: 389-420. PMID 18304003 DOI: 10.1146/Annurev.Immunol.26.021607.090404 |
0.421 |
|
| 2008 |
Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ. Identification of host proteins required for HIV infection through a functional genomic screen. Science (New York, N.Y.). 319: 921-6. PMID 18187620 DOI: 10.1126/Science.1152725 |
0.394 |
|
| 2007 |
Yu F, Yao H, Zhu P, Zhang X, Pan Q, Gong C, Huang Y, Hu X, Su F, Lieberman J, Song E. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell. 131: 1109-23. PMID 18083101 DOI: 10.1016/J.Cell.2007.10.054 |
0.332 |
|
| 2007 |
Jiang S, Rasmussen RA, Nolan KM, Frankel FR, Lieberman J, McClure HM, Williams KM, Babu US, Raybourne RB, Strobert E, Ruprecht RM. Live attenuated Listeria monocytogenes expressing HIV Gag: immunogenicity in rhesus monkeys. Vaccine. 25: 7470-9. PMID 17854955 DOI: 10.1016/J.Vaccine.2007.08.013 |
0.325 |
|
| 2007 |
de Fougerolles A, Vornlocher HP, Maraganore J, Lieberman J. Interfering with disease: a progress report on siRNA-based therapeutics. Nature Reviews. Drug Discovery. 6: 443-53. PMID 17541417 DOI: 10.1038/Nrd2310 |
0.301 |
|
| 2007 |
Lee-Kirsch MA, Chowdhury D, Harvey S, Gong M, Senenko L, Engel K, Pfeiffer C, Hollis T, Gahr M, Perrino FW, Lieberman J, Hubner N. A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus. Journal of Molecular Medicine (Berlin, Germany). 85: 531-7. PMID 17440703 DOI: 10.1007/S00109-007-0199-9 |
0.323 |
|
| 2007 |
Pipkin ME, Lieberman J. Delivering the kiss of death: progress on understanding how perforin works. Current Opinion in Immunology. 19: 301-8. PMID 17433871 DOI: 10.1016/J.Coi.2007.04.011 |
0.39 |
|
| 2007 |
Peer D, Zhu P, Carman CV, Lieberman J, Shimaoka M. Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1. Proceedings of the National Academy of Sciences of the United States of America. 104: 4095-100. PMID 17360483 DOI: 10.1073/Pnas.0608491104 |
0.385 |
|
| 2006 |
Ranjbar S, Tsytsykova AV, Lee SK, Rajsbaum R, Falvo JV, Lieberman J, Shankar P, Goldfeld AE. NFAT5 regulates HIV-1 in primary monocytes via a highly conserved long terminal repeat site. Plos Pathogens. 2: e130. PMID 17173480 DOI: 10.1371/Journal.Ppat.0020130 |
0.411 |
|
| 2006 |
Dykxhoorn DM, Lieberman J. Silencing viral infection. Plos Medicine. 3: e242. PMID 16848617 DOI: 10.1371/Journal.Pmed.0030242 |
0.305 |
|
| 2006 |
Dykxhoorn DM, Lieberman J. Running interference: prospects and obstacles to using small interfering RNAs as small molecule drugs. Annual Review of Biomedical Engineering. 8: 377-402. PMID 16834561 DOI: 10.1146/Annurev.Bioeng.8.061505.095848 |
0.357 |
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| 2006 |
Chowdhury D, Beresford PJ, Zhu P, Zhang D, Sung JS, Demple B, Perrino FW, Lieberman J. The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death. Molecular Cell. 23: 133-42. PMID 16818237 DOI: 10.1016/J.Molcel.2006.06.005 |
0.318 |
|
| 2006 |
Zhu P, Zhang D, Chowdhury D, Martinvalet D, Keefe D, Shi L, Lieberman J. Granzyme A, which causes single-stranded DNA damage, targets the double-strand break repair protein Ku70. Embo Reports. 7: 431-7. PMID 16440001 DOI: 10.1038/Sj.Embor.7400622 |
0.398 |
|
| 2006 |
Dykxhoorn DM, Palliser D, Lieberman J. The silent treatment: siRNAs as small molecule drugs. Gene Therapy. 13: 541-52. PMID 16397510 DOI: 10.1038/Sj.Gt.3302703 |
0.317 |
|
| 2006 |
Palliser D, Chowdhury D, Wang QY, Lee SJ, Bronson RT, Knipe DM, Lieberman J. An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection. Nature. 439: 89-94. PMID 16306938 DOI: 10.1038/Nature04263 |
0.387 |
|
| 2006 |
Lieberman J. Harnessing RNA interference to prevent or treat HSV-2 and HIV Retrovirology. 3: 1-1. DOI: 10.1186/1742-4690-3-S1-S48 |
0.437 |
|
| 2006 |
Silberstein LE, Dykxhoorn D, Le Y, Honczarenko M, Lieberman J, Glodek A. Focal Adhesion Kinase (FAK) Is Required for CXCL12-Induced Dhemotaxis and Adhesion to VCAM-1 in B Lymphocytes and Hematopoietic Stem/Progenitor Cells. Blood. 108: 1325-1325. DOI: 10.1182/Blood.V108.11.1325.1325 |
0.364 |
|
| 2005 |
Keefe D, Shi L, Feske S, Massol R, Navarro F, Kirchhausen T, Lieberman J. Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis. Immunity. 23: 249-62. PMID 16169498 DOI: 10.1016/J.Immuni.2005.08.001 |
0.361 |
|
| 2005 |
Feng H, Zhang D, Palliser D, Zhu P, Cai S, Schlesinger A, Maliszewski L, Lieberman J. Listeria-infected myeloid dendritic cells produce IFN-beta, priming T cell activation. Journal of Immunology (Baltimore, Md. : 1950). 175: 421-32. PMID 15972676 DOI: 10.4049/Jimmunol.175.1.421 |
0.748 |
|
| 2005 |
Liu L, Xu Z, Fuhlbrigge RC, Peña-Cruz V, Lieberman J, Kupper TS. Vaccinia virus induces strong immunoregulatory cytokine production in healthy human epidermal keratinocytes: a novel strategy for immune evasion. Journal of Virology. 79: 7363-70. PMID 15919891 DOI: 10.1128/Jvi.79.12.7363-7370.2005 |
0.355 |
|
| 2005 |
Song E, Zhu P, Lee SK, Chowdhury D, Kussman S, Dykxhoorn DM, Feng Y, Palliser D, Weiner DB, Shankar P, Marasco WA, Lieberman J. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nature Biotechnology. 23: 709-17. PMID 15908939 DOI: 10.1038/Nbt1101 |
0.443 |
|
| 2005 |
Shi L, Keefe D, Durand E, Feng H, Zhang D, Lieberman J. Granzyme B binds to target cells mostly by charge and must be added at the same time as perforin to trigger apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 174: 5456-61. PMID 15843543 DOI: 10.4049/Jimmunol.174.9.5456 |
0.379 |
|
| 2005 |
Lee SK, Dykxhoorn DM, Kumar P, Ranjbar S, Song E, Maliszewski LE, François-Bongarçon V, Goldfeld A, Swamy NM, Lieberman J, Shankar P. Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIV. Blood. 106: 818-26. PMID 15831707 DOI: 10.1182/Blood-2004-10-3959 |
0.768 |
|
| 2005 |
Martinvalet D, Zhu P, Lieberman J. Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis. Immunity. 22: 355-70. PMID 15780992 DOI: 10.1016/J.Immuni.2005.02.004 |
0.307 |
|
| 2005 |
Shankar P, Manjunath N, Lieberman J. The prospect of silencing disease using RNA interference. Jama. 293: 1367-73. PMID 15769970 DOI: 10.1001/Jama.293.11.1367 |
0.303 |
|
| 2005 |
Dykxhoorn DM, Lieberman J. The silent revolution: RNA interference as basic biology, research tool, and therapeutic. Annual Review of Medicine. 56: 401-23. PMID 15660519 DOI: 10.1146/Annurev.Med.56.082103.104606 |
0.359 |
|
| 2005 |
Lieberman J. The Kiss of Death: A New Model for How Perforin Delivers Granzymes to Target Cells Retrovirology. 2: 1-1. DOI: 10.1186/1742-4690-2-S1-S106 |
0.368 |
|
| 2004 |
François-Bongarcon V, Feng Y, Lee SK, Chen G, Shankar P, Liu Y, Tao X, Shao Y, Lieberman J. Cross-clade CD8 T-cell responses to HIV(IIIB) and Chinese B' and C/B' viruses in North American and Chinese HIV-seropositive donors. Journal of Acquired Immune Deficiency Syndromes (1999). 37: 1435-44. PMID 15602120 DOI: 10.1097/01.Qai.0000145220.81304.B0 |
0.416 |
|
| 2004 |
Ince MN, Harnisch B, Xu Z, Lee SK, Lange C, Moretta L, Lederman M, Lieberman J. Increased expression of the natural killer cell inhibitory receptor CD85j/ILT2 on antigen-specific effector CD8 T cells and its impact on CD8 T-cell function. Immunology. 112: 531-42. PMID 15270723 DOI: 10.1046/J.1365-2567.2004.01907.X |
0.466 |
|
| 2004 |
Lieberman J. Tracking the killers: how should we measure CD8 T cells in HIV infection? Aids. 18: 1489-1493. PMID 15238766 DOI: 10.1097/01.Aids.0000131320.75396.4D |
0.431 |
|
| 2004 |
Lange CG, Xu Z, Patterson BK, Medvik K, Harnisch B, Asaad R, Valdez H, Lee SJ, Landay A, Lieberman J, Lederman MM. Proliferation responses to HIVp24 during antiretroviral therapy do not reflect improved immune phenotype or function. Aids. 18: 605-613. PMID 15090765 DOI: 10.1097/00002030-200403050-00004 |
0.436 |
|
| 2003 |
De Groot AS, Jesdale B, Martin W, Saint Aubin C, Sbai H, Bosma A, Lieberman J, Skowron G, Mansourati F, Mayer KH. Mapping cross-clade HIV-1 vaccine epitopes using a bioinformatics approach. Vaccine. 21: 4486-504. PMID 14505932 DOI: 10.1016/S0264-410X(03)00390-6 |
0.343 |
|
| 2003 |
Lieberman J, Fan Z. Nuclear war: the granzyme A-bomb Current Opinion in Immunology. 15: 553-559. PMID 14499264 DOI: 10.1016/S0952-7915(03)00108-0 |
0.415 |
|
| 2003 |
Lieberman J, Song E, Lee SK, Shankar P. Interfering with disease: opportunities and roadblocks to harnessing RNA interference. Trends in Molecular Medicine. 9: 397-403. PMID 13129706 DOI: 10.1016/S1471-4914(03)00143-6 |
0.353 |
|
| 2003 |
Wan J, Martinvalet D, Ji X, Lois C, Kaech SM, Von Andrian UH, Lieberman J, Ahmed R, Manjunath N. The Bcl-2 family pro-apoptotic molecule, BNIP3 regulates activation-induced cell death of effector cytotoxic T lymphocytes. Immunology. 110: 10-7. PMID 12941136 DOI: 10.1046/J.1365-2567.2003.01710.X |
0.431 |
|
| 2003 |
Song E, Lee SK, Dykxhoorn DM, Novina C, Zhang D, Crawford K, Cerny J, Sharp PA, Lieberman J, Manjunath N, Shankar P. Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages. Journal of Virology. 77: 7174-81. PMID 12805416 DOI: 10.1128/Jvi.77.13.7174-7181.2003 |
0.42 |
|
| 2003 |
Lieberman J. The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal Nature Reviews Immunology. 3: 361-370. PMID 12766758 DOI: 10.1038/Nri1083 |
0.45 |
|
| 2003 |
Kushner N, Zhang D, Touzjian N, Essex M, Lieberman J, Lu Y. A fragment of anthrax lethal factor delivers proteins to the cytosol without requiring protective antigen. Proceedings of the National Academy of Sciences of the United States of America. 100: 6652-7. PMID 12740437 DOI: 10.1073/Pnas.1131930100 |
0.377 |
|
| 2003 |
Gu X, Laouar A, Wan J, Daheshia M, Lieberman J, Yokoyama WM, Katz HR, Manjunath N. The gp49B1 inhibitory receptor regulates the IFN-gamma responses of T cells and NK cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 4095-101. PMID 12682239 DOI: 10.4049/Jimmunol.170.8.4095 |
0.437 |
|
| 2003 |
Fan Z, Beresford PJ, Oh DY, Zhang D, Lieberman J. Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. Cell. 112: 659-72. PMID 12628186 DOI: 10.1016/S0092-8674(03)00150-8 |
0.308 |
|
| 2003 |
Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P, Lieberman J. RNA interference targeting Fas protects mice from fulminant hepatitis. Nature Medicine. 9: 347-51. PMID 12579197 DOI: 10.1038/Nm828 |
0.312 |
|
| 2003 |
Fan Z, Beresford PJ, Zhang D, Xu Z, Novina CD, Yoshida A, Pommier Y, Lieberman J. Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A. Nature Immunology. 4: 145-53. PMID 12524539 DOI: 10.1038/Ni885 |
0.403 |
|
| 2003 |
Geiben-Lynn R, Kursar M, Brown NV, Addo MM, Shau H, Lieberman J, Luster AD, Walker BD. HIV-1 antiviral activity of recombinant natural killer cell enhancing factors, NKEF-A and NKEF-B, members of the peroxiredoxin family. Journal of Biological Chemistry. 278: 1569-1574. PMID 12421812 DOI: 10.1074/Jbc.M209964200 |
0.467 |
|
| 2003 |
Zhang D, Shankar P, Xu Z, Harnisch B, Chen G, Lange C, Lee SJ, Valdez H, Lederman MM, Lieberman J. Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic. Blood. 101: 226-35. PMID 12393740 DOI: 10.1182/Blood-2002-03-0791 |
0.465 |
|
| 2003 |
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee S, Collman RG, Lieberman J, Shankar P, Sharp PA. Erratum: siRNA-directed inhibition of HIV-1 infection Nature Medicine. 9: 1433-1433. DOI: 10.1038/Nm1103-1433A |
0.362 |
|
| 2003 |
Lieberman J. Mechanisms of granule-mediated cytotoxicity Current Opinion in Immunology. 15: 513-515. DOI: 10.1016/S0952-7915(03)00102-X |
0.454 |
|
| 2002 |
Lee SK, Xu Z, Lieberman J, Shankar P. The functional CD8 T cell response to HIV becomes type-specific in progressive disease. The Journal of Clinical Investigation. 110: 1339-47. PMID 12417573 DOI: 10.1172/Jci16028 |
0.454 |
|
| 2002 |
Lieberman J. Defying death - HIV mutation to evade cytotoxic T lymphocytes New England Journal of Medicine. 347: 1203-1204. PMID 12374884 DOI: 10.1056/Nejmcibr022067 |
0.415 |
|
| 2002 |
Lieberman J, Manjunath N, Shankar P. Avoiding the kiss of death: how HIV and other chronic viruses survive. Current Opinion in Immunology. 14: 478-86. PMID 12088683 DOI: 10.1016/S0952-7915(02)00366-7 |
0.435 |
|
| 2002 |
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman RG, Lieberman J, Shankar P, Sharp PA. siRNA-directed inhibition of HIV-1 infection. Nature Medicine. 8: 681-6. PMID 12042777 DOI: 10.1038/Nm725 |
0.406 |
|
| 2002 |
Lieberman J, Frankel FR. Engineered Listeria monocytogenes as an AIDS vaccine. Vaccine. 20: 2007-10. PMID 11983264 DOI: 10.1016/S0264-410X(02)00088-9 |
0.4 |
|
| 2002 |
Fan Z, Beresford PJ, Zhang D, Lieberman J. HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A. Molecular and Cellular Biology. 22: 2810-20. PMID 11909973 DOI: 10.1128/Mcb.22.8.2810-2820.2002 |
0.34 |
|
| 2001 |
Manjunath N, Shankar P, Wan J, Weninger W, Crowley MA, Hieshima K, Springer TA, Fan X, Shen H, Lieberman J, von Andrian UH. Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes. The Journal of Clinical Investigation. 108: 871-8. PMID 11560956 DOI: 10.1172/Jci13296 |
0.397 |
|
| 2001 |
Beresford PJ, Zhang D, Oh DY, Fan Z, Greer EL, Russo ML, Jaju M, Lieberman J. Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks. The Journal of Biological Chemistry. 276: 43285-93. PMID 11555662 DOI: 10.1074/Jbc.M108137200 |
0.336 |
|
| 2001 |
Lieberman J, Shankar P, Manjunath N, Andersson J. Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection. Blood. 98: 1667-1677. PMID 11535496 DOI: 10.1182/Blood.V98.6.1667 |
0.458 |
|
| 2001 |
Chen G, Shankar P, Lange C, Valdez H, Skolnik PR, Wu L, Manjunath N, Lieberman J. CD8 T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection. Blood. 98: 156-164. PMID 11418475 DOI: 10.1182/Blood.V98.1.156 |
0.466 |
|
| 2001 |
Sharif-Askari E, Alam A, Rhéaume E, Beresford PJ, Scotto C, Sharma K, Lee D, DeWolf WE, Nuttall ME, Lieberman J, Sékaly RP. Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation. The Embo Journal. 20: 3101-13. PMID 11406587 DOI: 10.1093/Emboj/20.12.3101 |
0.366 |
|
| 2001 |
Zhang D, Beresford PJ, Greenberg AH, Lieberman J. Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis. Proceedings of the National Academy of Sciences of the United States of America. 98: 5746-51. PMID 11331782 DOI: 10.1073/Pnas.101329598 |
0.346 |
|
| 2001 |
Zhang D, Pasternack MS, Beresford PJ, Wagner L, Greenberg AH, Lieberman J. Induction of rapid histone degradation by the cytotoxic T lymphocyte protease Granzyme A. The Journal of Biological Chemistry. 276: 3683-90. PMID 11060286 DOI: 10.1074/Jbc.M005390200 |
0.396 |
|
| 2000 |
Trimble L, Perales M, Knazek R, Lieberman J. Serum enhances the ex vivo generation of HIV-specific cytotoxic T cells. Biotechnology and Bioengineering. 50: 521-528. PMID 18627014 DOI: 10.1002/(Sici)1097-0290(19960605)50:5<521::Aid-Bit6>3.0.Co;2-H |
0.431 |
|
| 2000 |
Friedman RS, Frankel FR, Xu Z, Lieberman J. Induction of human immunodeficiency virus (HIV)-specific CD8 T-cell responses by Listeria monocytogenes and a hyperattenuated Listeria strain engineered to express HIV antigens. Journal of Virology. 74: 9987-93. PMID 11024127 DOI: 10.1128/Jvi.74.21.9987-9993.2000 |
0.438 |
|
| 2000 |
Trimble LA, Shankar P, Patterson M, Daily JP, Lieberman J. Human Immunodeficiency Virus-Specific Circulating CD8 T Lymphocytes Have Down-Modulated CD3ζ and CD28, Key Signaling Molecules for T-Cell Activation Journal of Virology. 74: 7320-7330. PMID 10906185 DOI: 10.1128/Jvi.74.16.7320-7330.2000 |
0.452 |
|
| 2000 |
Lu Y, Friedman R, Kushner N, Doling A, Thomas L, Touzjian N, Starnbach M, Lieberman J. Genetically modified anthrax lethal toxin safely delivers whole HIV protein antigens into the cytosol to induce T cell immunity. Proceedings of the National Academy of Sciences of the United States of America. 97: 8027-32. PMID 10884430 DOI: 10.1073/Pnas.97.14.8027 |
0.426 |
|
| 2000 |
Mackewicz CE, Lieberman J, Froelich C, Levy JA. HIV virions and HIV infection in vitro are unaffected by human granzymes A and B. Aids Research and Human Retroviruses. 16: 367-72. PMID 10716374 DOI: 10.1089/088922200309241 |
0.445 |
|
| 2000 |
Manjunath N, Shankar P, Stockton B, Dubey PD, Lieberman J, von Andrian UH. A transgenic mouse model to analyze CD8(+) effector T cell differentiation in vivo. Proceedings of the National Academy of Sciences of the United States of America. 96: 13932-7. PMID 10570176 DOI: 10.1073/Pnas.96.24.13932 |
0.441 |
|
| 2000 |
Shankar P, Russo M, Harnisch B, Patterson M, Skolnik P, Lieberman J. Impaired function of circulating HIV-specific CD8(+) T cells in chronic human immunodeficiency virus infection. Blood. 96: 3094-3101. DOI: 10.1182/Blood.V96.9.3094.H8003094_3094_3101 |
0.451 |
|
| 2000 |
Trimble LA, Kam LW, Friedman RS, Xu Z, Lieberman J. CD3ζ and CD28 down-modulation on CD8 T cells during viral infection Blood. 96: 1021-1029. DOI: 10.1182/Blood.V96.3.1021 |
0.388 |
|
| 1999 |
Lori F, Jessen H, Lieberman J, Finzi D, Rosenberg E, Tinelli C, Walker B, Siliciano RF, Lisziewicz J. Treatment of human immunodeficiency virus infection with hydroxyurea, didanosine, and a protease inhibitor before seroconversion is associated with normalized immune parameters and limited viral reservoir. The Journal of Infectious Diseases. 180: 1827-32. PMID 10558937 DOI: 10.1086/315113 |
0.405 |
|
| 1999 |
Lori F, Rosenberg E, Lieberman J, Foli A, Maserati R, Seminari E, Alberici F, Walker B, Lisziewicz J. Hydroxyurea and Didanosine Long-Term Treatment Prevents HIV Breakthrough and Normalizes Immune Parameters Aids Research and Human Retroviruses. 15: 1333-1338. PMID 10515148 DOI: 10.1089/088922299310034 |
0.416 |
|
| 1999 |
Andersson J, Behbahani H, Lieberman J, Connick E, Landay A, Patterson B, Sönnerborg A, Loré K, Uccini S, Fehniger TE. Perforin is not co-expressed with granzyme A within cytotoxic granules in CD8 T lymphocytes present in lymphoid tissue during chronic HIV infection. Aids (London, England). 13: 1295-303. PMID 10449281 DOI: 10.1097/00002030-199907300-00005 |
0.344 |
|
| 1999 |
Lieberman J, Trimble LA, Friedman RS, Lisziewicz J, Lori F, Shankar P, Jessen H. Expansion of CD57 and CD62L-CD45RA+ CD8 T lymphocytes correlates with reduced viral plasma RNA after primary HIV infection. Aids (London, England). 13: 891-9. PMID 10371169 DOI: 10.1097/00002030-199905280-00004 |
0.414 |
|
| 1999 |
Beresford PJ, Xia Z, Greenberg AH, Lieberman J. Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation. Immunity. 10: 585-94. PMID 10367904 DOI: 10.1016/S1074-7613(00)80058-8 |
0.362 |
|
| 1999 |
Trimble LA, Xu Z, Lieberman J. Clonal expansion of antigen-specific CD8 + cytotoxic T lymphocytes is regulated by late exposure to serum to prevent apoptosis Journal of Immunological Methods. 225: 39-52. PMID 10365780 DOI: 10.1016/S0022-1759(99)00026-5 |
0.382 |
|
| 1999 |
Lisziewicz J, Rosenberg E, Lieberman J, Jessen H, Lopalco L, Siliciano R, Walker B, Lori F. Control of HIV despite the discontinuation of antiretroviral therapy. The New England Journal of Medicine. 340: 1683-4. PMID 10348681 DOI: 10.1056/Nejm199905273402114 |
0.366 |
|
| 1999 |
Lori F, Jessen H, Lieberman J, Clerici M, Tinelli C, Lisziewicz J. Immune restoration by combination of a cytostatic drug (hydroxyurea) and anti-HIV drugs (didanosine and indinavir) Aids Research and Human Retroviruses. 15: 619-624. PMID 10331440 DOI: 10.1089/088922299310917 |
0.42 |
|
| 1999 |
MacDonald G, Shi L, Vande Velde C, Lieberman J, Greenberg AH. Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis. The Journal of Experimental Medicine. 189: 131-44. PMID 9874570 DOI: 10.1084/Jem.189.1.131 |
0.323 |
|
| 1999 |
Shankar P, Xu Z, Lieberman J. Viral-specific cytotoxic T lymphocytes lyse human immunodeficiency virus-infected primary T lymphocytes by the granule exocytosis pathway. Blood. 94: 3084-3093. DOI: 10.1182/Blood.V94.9.3084 |
0.482 |
|
| 1998 |
Shankar P, Sprang H, Lieberman J. Effective lysis of HIV-1-infected primary CD4+ T cells by a cytotoxic T-lymphocyte clone directed against a novel A2-restricted reverse-transcriptase epitope Journal of Acquired Immune Deficiency Syndromes. 19: 111-120. PMID 9768618 DOI: 10.1097/00042560-199810010-00002 |
0.46 |
|
| 1998 |
Xia Z, Kam CM, Huang C, Powers JC, Mandle RJ, Stevens RL, Lieberman J. Expression and purification of enzymatically active recombinant granzyme B in a baculovirus system. Biochemical and Biophysical Research Communications. 243: 384-9. PMID 9480818 DOI: 10.1006/Bbrc.1998.8102 |
0.379 |
|
| 1998 |
Trimble LA, Lieberman J. Circulating CD8 T Lymphocytes in Human Immunodeficiency Virus-Infected Individuals Have Impaired Function and Downmodulate CD3ζ, the Signaling Chain of the T-Cell Receptor Complex Blood. 91: 585-594. DOI: 10.1182/Blood.V91.2.585.585_585_594 |
0.454 |
|
| 1997 |
Beresford PJ, Kam C, Powers JC, Lieberman J. Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them Proceedings of the National Academy of Sciences of the United States of America. 94: 9285-9290. PMID 9256474 DOI: 10.1073/Pnas.94.17.9285 |
0.343 |
|
| 1997 |
Lieberman J, Fabry JA, Fong DM, Parkerson GR. Recognition of a Small Number of Diverse Epitopes Dominates the Cytotoxic T Lymphocyte Response to HIV Type 1 in an Infected Individual Aids Research and Human Retroviruses. 13: 383-392. PMID 9075479 DOI: 10.1089/Aid.1997.13.383 |
0.424 |
|
| 1997 |
Lieberman J, Skolnik PR, Parkerson GR, Fabry JA, Landry B, Bethel J, Kagan J. Safety of Autologous, Ex Vivo-Expanded Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T-Lymphocyte Infusion in HIV-Infected Patients Blood. 90: 2196-2206. DOI: 10.1182/Blood.V90.6.2196 |
0.428 |
|
| 1997 |
Shankar P, Serulneck TM, Dezube BJ, Lieberman J. Drugs That Inhibit Herpesvirus Dna Synthesis Block In Vitro Activation Of The Kaposi'S Sarcoma-Associated Herpes Virus(Kshv) In Peripheral Blood Mononuclear Cells.: 40 Journal of Acquired Immune Deficiency Syndromes. 14. DOI: 10.1097/00042560-199704010-00081 |
0.32 |
|
| 1996 |
Buchsbaum RJ, Fabry JA, Lieberman J. EBV-specific cytotoxic T lymphocytes protect against human EBV-associated lymphoma in scid mice. Immunology Letters. 52: 145-52. PMID 8905410 DOI: 10.1016/0165-2478(96)02602-8 |
0.356 |
|
| 1996 |
Shankar P, Fabry JA, Fong DM, Lieberman J. Three regions of HIV-1 gp160 contain clusters of immunodominant CTL epitopes. Immunology Letters. 52: 23-30. PMID 8877415 DOI: 10.1016/0165-2478(96)02574-6 |
0.329 |
|
| 1996 |
Perales M, Skolnik PR, Lieberman J. Effect of Interleukin 12 on in Vitro HIV Type 1 Replication Depends on Clinical Stage Aids Research and Human Retroviruses. 12: 659-668. PMID 8744576 DOI: 10.1089/Aid.1996.12.659 |
0.323 |
|
| 1996 |
Roberts CGP, Meister GE, Jesdale BM, Lieberman J, Berzofsky JA, Groot ASD. Prediction of HIV peptide epitopes by a novel algorithm. Aids Research and Human Retroviruses. 12: 593-610. PMID 8743085 DOI: 10.1089/Aid.1996.12.593 |
0.337 |
|
| 1995 |
Srinivas RV, Su T, Trimble LA, Lieberman J, Ardman B. Enhanced susceptibility to human immunodeficiency virus infection in CD4+ T lymphocytes genetically deficient in CD43. Aids Research and Human Retroviruses. 11: 1015-1021. PMID 8554898 DOI: 10.1089/Aid.1995.11.1015 |
0.424 |
|
| 1995 |
Shankar P, Fabry J, Lieberman J. A Simple Method to Selectively Expand HIV-1 Specific Cytotoxic T Lymphocytes in Vitro Immunological Investigations. 24: 489-497. PMID 7790045 DOI: 10.3109/08820139509066845 |
0.438 |
|
| 1995 |
Lieberman J, Fabry JA, Shankar P, Beckett L, Skolnik PR. Ex vivo expansion of HIV type 1-specific cytolytic T cells from HIV type 1-seropositive subjects. Aids Research and Human Retroviruses. 11: 257-271. PMID 7742040 DOI: 10.1089/Aid.1995.11.257 |
0.423 |
|
| 1995 |
Perales M, Schwartz DH, Fabry JA, Lieberman J. A vaccinia-gp160-based vaccine but not a gp160 protein vaccine elicits anti-gp160 cytotoxic T lymphocytes in some HIV-1 seronegative vaccinees. Journal of Acquired Immune Deficiency Syndromes. 10: 27-35. DOI: 10.1097/00042560-199509000-00004 |
0.387 |
|
| 1994 |
Lieberman J, Buchsbaum RJ. Using T cells to treat B-cell cancers. The New England Journal of Medicine. 330: 1231-3. PMID 8139635 DOI: 10.1056/Nejm199404283301711 |
0.374 |
|
| 1994 |
Schwartz D, Sharma U, Busch M, Weinhold K, Matthews T, Lieberman J, Birx D, Farzedagen H, Margolick J, Quinn T, Davis B, Bagasra O, Pomerantz R, Viscidi R. Absence of Recoverable Infectious Virus and Unique Immune Responses in an Asymptomatic HIV+ Long-Term Survivor Aids Research and Human Retroviruses. 10: 1703-1711. PMID 7888230 DOI: 10.1089/Aid.1994.10.1703 |
0.357 |
|
| 1987 |
Lieberman J, Raulet DH. T cell gamma receptor Immunologic Research. 6: 288-293. PMID 3323346 DOI: 10.1007/Bf02935523 |
0.331 |
|
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