Thomas G. Back - Publications

Affiliations: 
University of Calgary, Calgary, Alberta, Canada 
Area:
Organic Chemistry
Website:
http://contacts.ucalgary.ca/info/chem/profiles/145-512

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Pastor A, Prinsloo R, Burford KN, Macdonald AR, Parvez M, Gendy C, Back TG. Synthesis of the Marine Alkaloid Cylindricine C and Serendipitous Synthesis of Its 2,13-Di- Stereoisomer. The Journal of Organic Chemistry. 88: 13813-13824. PMID 37722076 DOI: 10.1021/acs.joc.3c01467  0.36
2023 Sands KN, Burman AL, Ansah-Asamoah E, Back TG. Chemistry Related to the Catalytic Cycle of the Antioxidant Ebselen. Molecules (Basel, Switzerland). 28. PMID 37175141 DOI: 10.3390/molecules28093732  0.74
2022 McMillan JDR, Sands KN, Cooney GS, Gelfand BS, Back TG. Unexpected Formation and Potent Antioxidant Activity of Macrocyclic Dimers Containing Disulfide and Selenide Groups. Angewandte Chemie (International Ed. in English). PMID 36264710 DOI: 10.1002/anie.202213744  0.314
2022 Doig AI, Tuck TA, LeBlanc B, Back TG. Synthesis, Catalytic GPx-like Activity, and SET Reactions of Conformationally Constrained 2,7-Dialkoxy-Substituted Naphthalene-1,8-diselenides. Acs Omega. 7: 27312-27323. PMID 35967016 DOI: 10.1021/acsomega.2c02286  0.329
2021 Sands KN, Gelfand BS, Back TG. One-Pot Synthesis of Aryl Selenonic Acids and Some Unexpected Byproducts. The Journal of Organic Chemistry. PMID 34269577 DOI: 10.1021/acs.joc.1c01369  0.317
2017 Malig TC, Ashkin MR, Burman AL, Barday M, Heyne BJM, Back TG. Comparison of free-radical inhibiting antioxidant properties of carvedilol and its phenolic metabolites. Medchemcomm. 8: 606-615. PMID 30108776 DOI: 10.1039/c7md00014f  0.699
2016 Press DJ, Back TG. The role of methoxy substituents in regulating the activity of selenides that serve as spirodioxyselenurane precursors and glutathione peroxidase mimetics Canadian Journal of Chemistry. 94: 305-311. DOI: 10.1139/cjc-2015-0329  0.304
2014 Zhu Y, Back TG. Preparation of 1,7- and 3,9-dideazapurines from 2-amino-3-iodo- and 3-amino-4-iodopyridines and activated acetylenes by conjugate addition and copper-catalyzed intramolecular arylation. The Journal of Organic Chemistry. 79: 11270-6. PMID 25333726 DOI: 10.1021/jo502150v  0.323
2013 McNeil NM, Matz MC, Back TG. Fluxional cyclic seleninate ester: NMR and computational studies, glutathione peroxidase-like behavior, and unexpected rearrangement. The Journal of Organic Chemistry. 78: 10369-82. PMID 24032451 DOI: 10.1021/jo401757m  0.304
2012 Gao D, Back TG. Indole synthesis by conjugate addition of anilines to activated acetylenes and an unusual ligand-free copper(II)-mediated intramolecular cross-coupling. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 14828-40. PMID 23019064 DOI: 10.1002/chem.201202307  0.304
2010 Weston MH, Parvez M, Back TG. Conjugate additions, aza-Cope, and dissociative rearrangements and unexpected electrocyclic ring closures in the reactions of 2-(2-pyrrolidinyl)-substituted heteroaromatic systems with acetylenic sulfones. The Journal of Organic Chemistry. 75: 5402-5. PMID 20614920 DOI: 10.1021/jo101030b  0.351
2010 Clary KN, Parvez M, Back TG. Rearrangements and intramolecular Diels-Alder reactions of normal and vinylogous aza-Morita-Baylis-Hillman products leading to isoindoline derivatives. The Journal of Organic Chemistry. 75: 3751-60. PMID 20443620 DOI: 10.1021/jo1005087  0.33
2010 Back TG, Clary KN, Gao D. Cycloadditions and cyclizations of acetylenic, allenic, and conjugated dienyl sulfones. Chemical Reviews. 110: 4498-553. PMID 20438124 DOI: 10.1021/cr1000546  0.385
2010 Iosub V, Haberl AR, Leung J, Tang M, Vembaiyan K, Parvez M, Back TG. Enantioselective synthesis of alpha-quaternary amino acid derivatives by sequential enzymatic desymmetrization and Curtius rearrangement of alpha,alpha-disubstituted malonate diesters. The Journal of Organic Chemistry. 75: 1612-9. PMID 20131857 DOI: 10.1021/jo902584r  0.364
2010 Back T, Clary K. Synthesis of Onychine and Formal Synthesis of Eupolauridine via the Vinylogous Aza-Morita-Baylis-Hillman Reaction Synlett. 2010: 2802-2804. DOI: 10.1055/s-0030-1259008  0.323
2010 Andersen DL, Back TG. ChemInform Abstract: Stereochemistry of Cuprate-Mediated Conjugate Additions of a 17-Iodoandrost-16-ene to (E)- and (Z)-6-Methylhept-2-en-4-one. Cheminform. 33: no-no. DOI: 10.1002/chin.200228241  0.732
2010 Back TG, Nakajima K. ChemInform Abstract: Synthesis of Substituted Piperidines, Indolizidines, Quinolizidines, and Pyrrolizidines via a Cycloaddition Strategy Using Acetylenic Sulfones as Alkene Dipole Equivalents. Cheminform. 30: no-no. DOI: 10.1002/chin.199942041  0.757
2010 Back TG, Dyck BP, Nan S. ChemInform Abstract: Asymmetric Electrophilic Methoxyselenenylations and Cyclizations with 3-Camphorseleno Derivatives. Cheminform. 30: no-no. DOI: 10.1002/chin.199930182  0.366
2010 BACK TG, NAKAJIMA K. ChemInform Abstract: Enantioselective Synthesis of (-)-Pumiliotoxin C from a Chiral Amino Ester and an Acetylenic Sulfone that Acts as an Alkene Dipole Equivalent. Cheminform. 30: no-no. DOI: 10.1002/chin.199906196  0.746
2010 BACK TG, NAKAJIMA K. ChemInform Abstract: Use of an Acetylenic Sulfone as an Alkene Dipole Equivalent in the Synthesis of (.+-.)-Pumiliotoxin C. Cheminform. 28: no-no. DOI: 10.1002/chin.199724225  0.724
2010 BACK TG, GLADSTONE PL. ChemInform Abstract: Synthesis of Two Novel Spiro Lactones Related to the B/C Ring System of Bakkenolides by Radical Cyclization. Cheminform. 25: no-no. DOI: 10.1002/chin.199406129  0.315
2009 Clary KN, Parvez M, Back TG. Preparation of 1-aryl-substituted isoindoline derivatives by sequential Morita-Baylis-Hillman and intramolecular Diels-Alder reactions. Organic & Biomolecular Chemistry. 7: 1226-30. PMID 19262944 DOI: 10.1039/b817954a  0.366
2009 Back TG. Design and synthesis of some biologically interesting natural and unnatural products based on organosulfur and selenium chemistry Canadian Journal of Chemistry. 87: 1657-1674. DOI: 10.1139/V09-133  0.404
2008 Gao D, Zhai H, Parvez M, Back TG. 1,3-Dipolar cycloadditions of acetylenic sulfones in solution and on solid supports. The Journal of Organic Chemistry. 73: 8057-68. PMID 18798677 DOI: 10.1021/jo801621d  0.327
2008 Weston MH, Nakajima K, Back TG. Tandem conjugate additions and 3-aza-Cope rearrangements of tertiary allyl amines and cyclic alpha-vinylamines with acetylenic sulfones. Applications to simple and iterative ring expansions leading to medium and large-ring nitrogen heterocycles. The Journal of Organic Chemistry. 73: 4630-7. PMID 18498198 DOI: 10.1021/Jo800600A  0.757
2008 Press DJ, Mercier EA, Kuzma D, Back TG. Substituent effects upon the catalytic activity of aromatic cyclic seleninate esters and spirodioxyselenuranes that act as glutathione peroxidase mimetics. The Journal of Organic Chemistry. 73: 4252-5. PMID 18433177 DOI: 10.1021/jo800381s  0.319
2007 Zhai H, Parvez M, Back TG. A highly stereoselective synthesis of (-)-(ent)-julifloridine from the cyclization of an alanine-derived chloroamine with an acetylenic sulfone. The Journal of Organic Chemistry. 72: 3853-8. PMID 17439181 DOI: 10.1021/jo0703101  0.413
2007 Sorbetti JM, Clary KN, Rankic DA, Wulff JE, Parvez M, Back TG. Aza-Morita-Baylis-Hillman reactions and cyclizations of conjugated dienes activated by sulfone, ester, and keto groups. The Journal of Organic Chemistry. 72: 3326-31. PMID 17381156 DOI: 10.1021/jo062655+  0.684
2006 Weston MH, Nakajima K, Parvez M, Back TG. Ring-expansion of tertiary cyclic alpha-vinylamines by tandem conjugate addition to (p-toluenesulfonyl)ethyne and formal 3-aza-Cope rearrangement. Chemical Communications (Cambridge, England). 3903-5. PMID 17268665 DOI: 10.1039/B607713G  0.728
2006 Back TG, Zhai H. Cyclizations and cycloadditions of acetylenic sulfones on solid supports. Chemical Communications (Cambridge, England). 326-8. PMID 16391749 DOI: 10.1039/b512016k  0.321
2005 Back TG, Kuzma D, Parvez M. Aromatic derivatives and tellurium analogues of cyclic seleninate esters and spirodioxyselenuranes that act as glutathione peroxidase mimetics. The Journal of Organic Chemistry. 70: 9230-6. PMID 16268595 DOI: 10.1021/jo0512711  0.31
2005 Back TG, Rankic DA, Sorbetti JM, Wulff JE. Morita-Baylis-Hillman reaction and cyclization of 1-(p-toluenesulfonyl)-1,3-butadiene with aldimines. Organic Letters. 7: 2377-9. PMID 15932202 DOI: 10.1002/CHIN.200544088  0.65
2005 Back TG, Hamilton MD, Lim VJ, Parvez M. Synthesis of the quinolizidine alkaloids (-)-lasubine II and (+/-)-myrtine by conjugate addition and intramolecular acylation of amino esters with acetylenic sulfones. The Journal of Organic Chemistry. 70: 967-72. PMID 15675856 DOI: 10.1021/jo048284j  0.345
2005 Back TG, Moussa Z. Mimetics of the Selenoenzyme Glutathione Peroxidase: Novel Structures and Unusual Catalytic Mechanisms Phosphorus, Sulfur, and Silicon and the Related Elements. 180: 767-776. DOI: 10.1080/10426500590906238  0.649
2004 Back TG, Wulff JE. A stereodivergent synthesis of virantmycin by an enzyme-mediated diester desymmetrization and a highly hindered aryl amination. Angewandte Chemie (International Ed. in English). 43: 6493-6. PMID 15578771 DOI: 10.1002/anie.200461327  0.641
2004 Back TG, Moussa Z, Parvez M. The exceptional glutathione peroxidase-like activity of di(3-hydroxypropyl) selenide and the unexpected role of a novel spirodioxaselenanonane intermediate in the catalytic cycle. Angewandte Chemie (International Ed. in English). 43: 1268-70. PMID 14991795 DOI: 10.1002/Anie.200353128  0.596
2004 Back TG, Moussa Z, Parvez M. PREPARATION AND X-RAY CRYSTAL STRUCTURES OF TWO ALIPHATIC SELENENYL BROMIDES STABILIZED BY N─SE COORDINATION Phosphorus, Sulfur, and Silicon and the Related Elements. 179: 2569-2579. DOI: 10.1080/10426500490494543  0.615
2003 Back TG, Pharis RP. Structure-Activity Studies of Brassinosteroids and the Search for Novel Analogues and Mimetics with Improved Bioactivity. Journal of Plant Growth Regulation. 22: 350-361. PMID 14676967 DOI: 10.1007/s00344-003-0057-0  0.34
2003 Back TG, Parvez M, Zhai H. Stereospecific rearrangements during the synthesis of pyrrolidines and related heterocycles from cyclizations of amino alcohols with vinyl Sulfones. The Journal of Organic Chemistry. 68: 9389-93. PMID 14629162 DOI: 10.1021/jo0350864  0.363
2003 Back TG, Moussa Z. Diselenides and allyl selenides as glutathione peroxidase mimetics. Remarkable activity of cyclic seleninates produced in situ by the oxidation of allyl omega-hydroxyalkyl selenides. Journal of the American Chemical Society. 125: 13455-60. PMID 14583041 DOI: 10.1021/Ja0357588  0.646
2003 Back TG, Pandyra A, Wulff JE. Regiochemical switching in Diels-Alder cycloadditions by change in oxidation state of removable diene sulfur substituents. Synthesis of carbazoles by sequential heteroannulation and Diels-Alder cycloaddition. The Journal of Organic Chemistry. 68: 3299-302. PMID 12688806 DOI: 10.1021/jo0268714  0.677
2003 Back TG, Parvez M, Wulff JE. Conjugate additions of o-iodoanilines and methyl anthranilates to acetylenic sulfones. A new route to quinolones including first syntheses of two alkaloids from the medicinal herb Ruta chalepensis. The Journal of Organic Chemistry. 68: 2223-33. PMID 12636385 DOI: 10.1021/jo026595t  0.705
2002 Back TG, Moussa Z. Remarkable activity of a novel cyclic seleninate ester as a glutathione peroxidase mimetic and its facile in situ generation from allyl 3-hydroxypropyl selenide. Journal of the American Chemical Society. 124: 12104-5. PMID 12371844 DOI: 10.1021/Ja028030K  0.658
2002 Back TG, Wulff JE. First syntheses of two quinoline alkaloids from the medicinal herb Ruta chalepensis via cyclization of an o-iodoaniline with an acetylenic sulfone. Chemical Communications (Cambridge, England). 1710-1. PMID 12196961 DOI: 10.1039/b205408f  0.631
2002 Back TG, Moussa Z, Parvez M. Asymmetric methoxyselenenylations and cyclizations with 3-camphorseleno electrophiles containing oxime substituents at C-2. Formation of an unusual oxaselenazole from an oxime-substituted selenenyl bromide. The Journal of Organic Chemistry. 67: 499-509. PMID 11798323 DOI: 10.1021/Jo016061C  0.658
2002 Back TG, Bethell RJ, Parvez M, Taylor JA. Preparation of vinylogous 2-sulfonylindolines by the palladium-catalyzed heteroannulation of o-iodoanilines with dienyl sulfones and their further transformation to indoles and carbazoles. The Journal of Organic Chemistry. 66: 8599-605. PMID 11735543 DOI: 10.1021/jo016080m  0.378
2002 Pharis RP, Janzen L, Nakajima SK, Zhu J, Back TG. Bioactivity of 25-hydroxy-, 26-hydroxy, 25,26-dihydroxy- and 25,26-epoxybrassinolide. Phytochemistry. 58: 1043-7. PMID 11730867 DOI: 10.1016/S0031-9422(01)00381-8  0.384
2001 Andersen DL, Back TG, Janzen L, Michalak K, Pharis RP, Sung GC. Design, synthesis, and bioactivity of the first nonsteroidal mimetics of brassinolide. The Journal of Organic Chemistry. 66: 7129-41. PMID 11597241 DOI: 10.1021/Jo015832+  0.728
2001 Back TG, Nava-Salgado VO, Payne JE. Synthesis of (+/-)-bakkenolide-A and its C-7, C-10, and C-7,10 epimers by means of an intramolecular Diels-Alder reaction. The Journal of Organic Chemistry. 66: 4361-8. PMID 11397178 DOI: 10.1021/jo015624h  0.401
2001 Back TG, Moussa Z. ChemInform Abstract: New Chiral Auxiliaries for Highly Stereoselective Asymmetric Methoxyselenenylations. Cheminform. 32: no-no. DOI: 10.1002/chin.200101055  0.62
2000 Back TG, Moussa Z. New chiral auxiliaries for highly stereoselective asymmetric methoxyselenenylations. Organic Letters. 2: 3007-9. PMID 10986094 DOI: 10.1021/Ol000187Z  0.65
2000 Back TG, Nakajima K. A convenient new route to piperidines, pyrrolizidines, indolizidines, and quinolizidines by cyclization of acetylenic sulfones with beta and gamma-chloroamines. Enantioselective total synthesis of indolizidines (-)-167B, (-)-209D, (-)-209B, and (-)-207A. The Journal of Organic Chemistry. 65: 4543-52. PMID 10959857 DOI: 10.1021/Jo000080P  0.75
2000 Back TG, Payne JE. A concise total synthesis of (+/-)-bakkenolide A by means of an intramolecular Diels-Alder reaction. Organic Letters. 1: 663-5. PMID 10905873 DOI: 10.1021/ol990747y  0.327
2000 Back TG, Janzen L, Nakajima SK, Pharis RP. Effect of chain length and ring size of alkyl and cycloalkyl side-chain substituents upon the biological activity of brassinosteroids. Preparation of novel analogues with activity exceeding that of brassinolide. The Journal of Organic Chemistry. 65: 3047-52. PMID 10814196 DOI: 10.1021/jo9917947  0.367
1999 Back TG, Janzen L, Nakajima SK, Pharis RP. Synthesis and Biological Activity of 25-Methoxy-, 25-Fluoro-, and 25-Azabrassinolide and 25-Fluorocastasterone: Surprising Effects of Heteroatom Substituents at C-25. The Journal of Organic Chemistry. 64: 5494-5498. PMID 11674612 DOI: 10.1021/jo990312o  0.348
1996 Back TG, Gladstone PL, Parvez M. Synthesis of Tricyclic beta-Methylene Spiro Lactones Related to Bakkenolides by Successive Radical Cyclization-High Pressure Diels-Alder Reactions. The Journal of Organic Chemistry. 61: 3806-3814. PMID 11667233 DOI: 10.1021/jo960111+  0.327
1993 Back TG, Blazecka PG, Krishna MV. A new synthesis of castasterone and brassinolide from stigmasterol. A concise and stereoselective elaboration of the side chain from a C-22 aldehyde Canadian Journal of Chemistry. 71: 156-163. DOI: 10.1139/v93-022  0.335
1989 Back TG, Lai EKY, Muralidharan KR. A new preparation of 3-substituted 2-(p-toluenesulfonyl)-1,3-dienes Tetrahedron Letters. 30: 6481-6482. DOI: 10.1016/S0040-4039(01)88999-1  0.313
1987 Back TG, Collins S, Krishna MV. Reactions of sulfonhydrazides with benzeneseleninic acid, selenium halides, and sulfur halides. A convenient preparation of selenosulfonates and thiosulfonates Canadian Journal of Chemistry. 65: 38-42. DOI: 10.1139/v87-009  0.303
1987 Back TG, Krishna MV, Muralidharan KR. A general synthesis of allenic sulfones from acetylenes using selenosulfonation Tetrahedron Letters. 28: 1737-1740. DOI: 10.1016/S0040-4039(00)95408-X  0.364
1986 Back TG, Proudfoot JR, Djerassi C. Application of selenosulfonation to marine sterol synthesis. Preparation of 24,28-dehydroaplysterol, xestosterol and ostreasterol from a common acetylenic intermediate Tetrahedron Letters. 27: 2187-2190. DOI: 10.1016/S0040-4039(00)84483-4  0.332
1984 Back TG. A convenient procedure for the reductive deselenization of selenides with nickel boride Journal of the Chemical Society, Chemical Communications. 1417-1418. DOI: 10.1039/C39840001417  0.316
1982 Back TG, Kerr RG. Oxidation of 1,1-disubstituted hydrazines with benzeneseleninic acid and selenium dioxide. Facile preparation of tetrazenes Canadian Journal of Chemistry. 60: 2711-2718. DOI: 10.1002/Chin.198308115  0.314
1981 Back TG. Oxidation of 1,1-disubstituted hydrazines to tetrazenes with benzeneseleninic acid Journal of the Chemical Society, Chemical Communications. 530-531. DOI: 10.1039/C39810000530  0.344
1981 Back TG, Collins S. Selenosulfonation: boron trifluoride catalyzed or thermal addition of selenosulfonates to olefins. A novel regio- and stereocontrolled synthesis of vinyl sulfones The Journal of Organic Chemistry. 46: 3249-3256. DOI: 10.1021/jo00329a021  0.313
1980 Back TG, Collins S. “Selenosulfonation”: the addition of selenolsulfonates to olefins Tetrahedron Letters. 21: 2215-2218. DOI: 10.1016/0040-4039(80)80006-2  0.311
1979 BARTON DHR, BREWSTER AG, HUI RAHF, LESTER DJ, LEY SV, BACK TG. ChemInform Abstract: OXIDATION OF ALCOHOLS USING BENZENESELENINIC ANHYDRIDE Chemischer Informationsdienst. 10. DOI: 10.1002/Chin.197910130  0.413
1978 Barton DHR, Brewster AG, Hui RAHF, Lester DJ, Ley SV, Back TG. Oxidation of alcohols using benzeneseleninic anhydride Journal of the Chemical Society, Chemical Communications. 952-954. DOI: 10.1039/C39780000952  0.453
1978 Back TG. Dehydrogenation of hydrazines and of 4-azacholestan-3-one with benzeneseleninic acid and benzeneseleninic anhydride Journal of the Chemical Society, Chemical Communications. 278-279. DOI: 10.1039/C39780000278  0.345
1977 Back TG, Barton DH, Rao BL. Reactions of relevance to the chemistry of aminoglycoside antibiotics. Part 6. A simple preparation of chlorohydrin benzoates from 1,2- and 1,3-glycols. Journal of the Chemical Society. Perkin Transactions 1. 15: 1715-8. PMID 561107 DOI: 10.1039/P19770001715  0.619
1977 Back TG, Barton DHR. Chemistry of hindered amines: synthesis and properties of di-t-butylamine and related compounds Journal of the Chemical Society-Perkin Transactions 1. 8: 924-927. DOI: 10.1039/P19770000924  0.309
1977 Moore JA, Kelly JE, Harpp DN, Back TG. Polymerization of a 1,2,3-Trithiane to a High Molecular Weight Polymer Macromolecules. 10: 718-719. DOI: 10.1021/ma60057a050  0.375
1976 Back TG, Barton DHR, Britten-Kelly MR, Guziec FS. Olefin synthesis by two-fold extrusion processes. Part 3. Synthesis and properties of hindered selenoketones (selones) Journal of the Chemical Society-Perkin Transactions 1. 8: 2079-2089. DOI: 10.1039/P19760002079  0.344
1975 Back TG, Barton DHR, Britten-Kelly MR, Guziec FS. Synthesis and properties of monomeric selenoketones Journal of the Chemical Society, Chemical Communications. 539-539. DOI: 10.1039/C39750000539  0.387
1975 Back TG, Barton DHR, Britten-Kelly MR, Guziec FSJ. Synthesis And Properties Of Monomeric Selenoketones Cheminform. 6. DOI: 10.1002/Chin.197540286  0.357
1970 Harpp DN, Ash DK, Back TG, Gleason JG, Orwig BA, VanHorn WF, Snyder JP. A new synthesis of unsymmetrical disulfides Tetrahedron Letters. 11: 3551-3554. DOI: 10.1016/S0040-4039(01)98525-9  0.518
1970 HARPP DN, ASH DK, BACK TG, GLEASON JG, ORWIG BA, VAN HORN WF, SNYDER JP. ChemInform Abstract: SYNTH. UNSYMM. DISULFIDE Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/chin.197047263  0.479
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