Pieter R. Cullis - Publications

Affiliations: 
University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Biochemistry, Molecular Biology

260 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhigaltsev IV, Cullis PR. Morphological Behavior of Liposomes and Lipid Nanoparticles. Langmuir : the Acs Journal of Surfaces and Colloids. 39: 3185-3193. PMID 36812413 DOI: 10.1021/acs.langmuir.2c02794  0.38
2021 Terada T, Kulkarni JA, Huynh A, Chen S, van der Meel R, Tam YYC, Cullis PR. Characterization of Lipid Nanoparticles Containing Ionizable Cationic Lipids Using Design-of-Experiments Approach. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 33439022 DOI: 10.1021/acs.langmuir.0c03039  0.369
2021 Terada T, Kulkarni JA, Huynh A, Tam YYC, Cullis P. Protective Effect of Edaravone against Cationic Lipid-Mediated Oxidative Stress and Apoptosis. Biological & Pharmaceutical Bulletin. 44: 144-149. PMID 33390543 DOI: 10.1248/bpb.b20-00679  0.309
2020 Francia V, Schiffelers RM, Cullis PR, Witzigmann D. The Biomolecular Corona of Lipid Nanoparticles for Gene Therapy. Bioconjugate Chemistry. PMID 32786370 DOI: 10.1021/Acs.Bioconjchem.0C00366  0.31
2020 Witzigmann D, Kulkarni JA, Leung J, Chen S, Cullis PR, van der Meel R. Lipid nanoparticle technology for therapeutic gene regulation in the liver. Advanced Drug Delivery Reviews. PMID 32622021 DOI: 10.1016/J.Addr.2020.06.026  0.326
2020 Ramezanpour M, Schmidt MML, Bashe BYM, Pruim JR, Link M, Cullis PR, Harper PE, Thewalt JL, Tieleman DP. Structural Properties of Inverted Hexagonal Phase: A Hybrid Computational and Experimental Approach. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 32437159 DOI: 10.1021/Acs.Langmuir.0C00600  0.309
2019 Akinc A, Maier MA, Manoharan M, Fitzgerald K, Jayaraman M, Barros S, Ansell S, Du X, Hope MJ, Madden TD, Mui BL, Semple SC, Tam YK, Ciufolini M, Witzigmann D, ... ... Cullis PR, et al. The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs. Nature Nanotechnology. 14: 1084-1087. PMID 31802031 DOI: 10.1038/S41565-019-0591-Y  0.351
2019 Uhl P, Grundmann C, Sauter M, Storck P, Tursch A, Özbek S, Leotta K, Roth R, Witzigmann D, Kulkarni JA, Fidelj V, Kleist C, Cullis PR, Fricker G, Mier W. Coating of PLA-nanoparticles with cyclic, arginine-rich cell penetrating peptides enables oral delivery of liraglutide. Nanomedicine : Nanotechnology, Biology, and Medicine. 102132. PMID 31783138 DOI: 10.1016/J.Nano.2019.102132  0.312
2019 Kulkarni JA, Witzigmann D, Leung J, Tam YYC, Cullis PR. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. PMID 31713568 DOI: 10.1039/C9Nr09347H  0.47
2019 Zhang W, Böttger R, Qin Z, Kulkarni JA, Vogler J, Cullis PR, Li SD. Phospholipid-Free Small Unilamellar Vesicles for Drug Targeting to Cells in the Liver. Small (Weinheim An Der Bergstrasse, Germany). e1901782. PMID 31490617 DOI: 10.1002/Smll.201901782  0.432
2019 Kulkarni JA, Witzigmann D, Chen S, Cullis PR, van der Meel R. Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics. Accounts of Chemical Research. PMID 31397996 DOI: 10.1021/Acs.Accounts.9B00368  0.387
2019 Hamano N, Böttger R, Lee SE, Yang Y, Kulkarni JA, Ip S, Cullis PR, Li SD. A robust microfluidic technology and a new lipid composition for fabrication of curcumin-loaded liposomes: Effect on the anticancer activity and safety of cisplatin. Molecular Pharmaceutics. PMID 31381352 DOI: 10.1021/Acs.Molpharmaceut.9B00583  0.37
2019 Ramezanpour M, Schmidt ML, Bodnariuc I, Kulkarni JA, Leung SSW, Cullis PR, Thewalt JL, Tieleman DP. Ionizable amino lipid interactions with POPC: implications for lipid nanoparticle function. Nanoscale. PMID 31334542 DOI: 10.1039/C9Nr02297J  0.468
2019 Jyotsana N, Sharma A, Chaturvedi A, Budida R, Scherr M, Kuchenbauer F, Lindner R, Noyan F, Sühs KW, Stangel M, Grote-Koska D, Brand K, Vornlocher HP, Eder M, Thol F, ... ... Cullis P, et al. Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo. Annals of Hematology. PMID 31104089 DOI: 10.1007/S00277-019-03713-Y  0.392
2019 Kulkarni JA, Witzigmann D, Leung J, van der Meel R, Zaifman J, Darjuan MM, Grisch-Chan HM, Thöny B, Tam YYC, Cullis PR. Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads. Nanoscale. PMID 31021343 DOI: 10.1039/C9Nr02004G  0.453
2019 Buck J, Grossen P, Cullis PR, Huwyler J, Witzigmann D. Lipid-Based DNA Therapeutics: Hallmarks of Non-Viral Gene Delivery. Acs Nano. PMID 30908008 DOI: 10.1021/Acsnano.8B07858  0.373
2019 Maclachlan I, Cullis P. "Diffusible-PEG-Lipid Stabilized Plasmid Lipid Particles" Advances in Genetics. 157-188. PMID 16243063 DOI: 10.1016/S0065-2660(05)53006-2  0.428
2019 Strilchuk A, Conway E, Pryzdial E, Cullis P, Kastrup C. P14. Abstract Title: Modulating Fibrinolysis using siRNA against Coagulation Factor XIII Thrombosis Research. 182: 9. DOI: 10.1016/J.Thromres.2019.09.027  0.311
2018 Chen S, Zaifman J, Kulkarni JA, Zhigaltsev IV, Tam YK, Ciufolini MA, Tam YYC, Cullis PR. Dexamethasone prodrugs as potent suppressors of the Immunostimulatory effects of lipid nanoparticle formulations of nucleic acids. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30026080 DOI: 10.1016/J.Jconrel.2018.07.026  0.372
2018 Kulkarni JA, Cullis PR, van der Meel R. Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility. Nucleic Acid Therapeutics. PMID 29683383 DOI: 10.1089/Nat.2018.0721  0.402
2018 Kulkarni JA, Darjuan MM, Mercer JE, Chen S, van der Meel R, Thewalt JL, Tam YYC, Cullis PR. On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA. Acs Nano. PMID 29614232 DOI: 10.1021/Acsnano.8B01516  0.445
2018 Tang WL, Tang WH, Szeitz A, Kulkarni J, Cullis P, Li SD. Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved delivery. Biomaterials. 166: 13-26. PMID 29529479 DOI: 10.1016/J.Biomaterials.2018.03.004  0.387
2018 Schmidt ML, Bashe BY, Bodnariuc I, Mercer JE, Leung SS, Ramezanpour M, Atsmon-Raz Y, Subramanian N, Cullis PR, Tieleman DP, Thewalt JL. Characterization of Phases and Interactions Among Lipids Involved in Drug Delivery: An NMR and Small-Angle X-Ray Scattering Study Biophysical Journal. 114: 16a. DOI: 10.1016/J.Bpj.2017.11.131  0.344
2017 Kulkarni JA, Tam YYC, Chen S, Tam YK, Zaifman J, Cullis PR, Biswas S. Rapid synthesis of lipid nanoparticles containing hydrophobic inorganic nanoparticles. Nanoscale. PMID 28876010 DOI: 10.1039/C7Nr03272B  0.41
2017 Cullis PR, Hope MJ. Lipid Nanoparticle Systems for Enabling Gene Therapies. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28412170 DOI: 10.1016/J.Ymthe.2017.03.013  0.359
2016 Lee JB, Zhang K, Tam YY, Quick J, Tam YK, Lin PJ, Chen S, Liu Y, Nair JK, Zlatev I, Rajeev KG, Manoharan M, Rennie PS, Cullis PR. A Glu-urea-Lys Ligand-conjugated Lipid Nanoparticle/siRNA System Inhibits Androgen Receptor Expression In Vivo. Molecular Therapy. Nucleic Acids. 5: e348. PMID 28131285 DOI: 10.1038/Mtna.2016.43  0.356
2016 Kulkarni JA, Myhre JL, Chen S, Tam YY, Danescu A, Richman JM, Cullis PR. Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 28038954 DOI: 10.1016/J.Nano.2016.12.014  0.442
2016 Wang H, Tam YY, Chen S, Zaifman J, van der Meel R, Ciufolini MA, Cullis PR. The Niemann-Pick C1 Inhibitor NP3.47 Enhances Gene Silencing Potency of Lipid Nanoparticles Containing siRNA. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27633442 DOI: 10.1038/Mt.2016.179  0.376
2016 Basha G, Ordobadi M, Scott WR, Cottle A, Liu Y, Wang H, Cullis PR. Lipid Nanoparticle Delivery of siRNA to Osteocytes Leads to Effective Silencing of SOST and Inhibition of Sclerostin In Vivo. Molecular Therapy. Nucleic Acids. 5: e363. PMID 27623445 DOI: 10.1038/Mtna.2016.68  0.34
2016 Chen S, Tam YY, Lin PJ, Sung MM, Tam YK, Cullis PR. Influence of particle Size on the in vivo potency of lipid nanoparticle formulations of siRNA. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27238441 DOI: 10.1016/J.Jconrel.2016.05.059  0.46
2016 Tharmarajah G, Ouellet E, Seira O, Liu J, Thomas A, Leaver T, Wild A, Li Y, Wang YT, Tetzlaff W, Hansen C, Cullis P, Taylor JR, Ramsay E. 614. Microfluidic Manufacture of RNA-Lipid Nanoparticles Leads to Highly Efficient Delivery of Potent Nucleic Acid Therapeutics for Controlling Gene Expression Molecular Therapy. 24: S243-S244. DOI: 10.1016/S1525-0016(16)33422-0  0.351
2016 Bashe BY, Leung SS, Delgado-Magnero KH, Ramezanpour M, Cullis PR, Tieleman DP, Thewalt J. Development of Lipid-Based Drug Delivery Systems for Gene Therapy: Physicochemical Characterization of Charged Lipid Interactions Biophysical Journal. 110: 247a. DOI: 10.1016/J.Bpj.2015.11.1358  0.482
2015 Leung AK, Tam YY, Chen S, Hafez IM, Cullis PR. Microfluidic Mixing: A General Method for Encapsulating Macromolecules in Lipid Nanoparticle Systems. The Journal of Physical Chemistry. B. 119: 8698-706. PMID 26087393 DOI: 10.1021/Acs.Jpcb.5B02891  0.455
2015 Ramishetti S, Kedmi R, Goldsmith M, Leonard F, Sprague AG, Godin B, Gozin M, Cullis PR, Dykxhoorn DM, Peer D. Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles. Acs Nano. PMID 26042619 DOI: 10.1021/Acsnano.5B02796  0.316
2015 Zhigaltsev IV, Tam YK, Leung AK, Cullis PR. Production of limit size nanoliposomal systems with potential utility as ultra-small drug delivery agents. Journal of Liposome Research. 1-7. PMID 25856305 DOI: 10.3109/08982104.2015.1025411  0.446
2015 Yamamoto Y, Lin PJ, Zhang F, Kawai Y, Beraldi E, Leong J, Matsuyama H, Cullis PR, Gleave ME. Effect of lipid nanoparticle siRNA delivery systems on silencing clusterin and progression in enzalutamide resistant prostate cancer in vivo. Journal of Clinical Oncology. 33: 256-256. DOI: 10.1200/Jco.2015.33.7_Suppl.256  0.315
2015 Jyotsana N, Sharma A, Chaturvedi A, Walsh C, Thomas A, Scherr M, Eder M, Battmer K, Kuchenbauer F, Laszlo S, Barchanski A, Goerlich K, Lindner R, Noyan F, Wolfram S, ... ... Cullis P, et al. Effective Treatment of Human CML By RNAi In Vivo in a Xenotransplantation Mouse Model Blood. 126: 1261-1261. DOI: 10.1182/Blood.V126.23.1261.1261  0.35
2014 Wan C, Allen TM, Cullis PR. Lipid nanoparticle delivery systems for siRNA-based therapeutics. Drug Delivery and Translational Research. 4: 74-83. PMID 25786618 DOI: 10.1007/S13346-013-0161-Z  0.456
2014 Leung AK, Tam YY, Cullis PR. Lipid nanoparticles for short interfering RNA delivery. Advances in Genetics. 88: 71-110. PMID 25409604 DOI: 10.1016/B978-0-12-800148-6.00004-3  0.345
2014 Chen S, Tam YY, Lin PJ, Leung AK, Tam YK, Cullis PR. Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration. Journal of Controlled Release : Official Journal of the Controlled Release Society. 196: 106-12. PMID 25285610 DOI: 10.1016/J.Jconrel.2014.09.025  0.409
2014 Walsh C, Ou K, Belliveau NM, Leaver TJ, Wild AW, Huft J, Lin PJ, Chen S, Leung AK, Lee JB, Hansen CL, Taylor RJ, Ramsay EC, Cullis PR. Microfluidic-based manufacture of siRNA-lipid nanoparticles for therapeutic applications. Methods in Molecular Biology (Clifton, N.J.). 1141: 109-20. PMID 24567134 DOI: 10.1007/978-1-4939-0363-4_6  0.36
2014 Wang S(, Hafez IM, Wang J, Ashtari M, Tieleman DP, Cullis PR, Thewalt JL. Optimizing Drug Release: Bilayer to Inverted Hexagonal Phase Transition of Cationic XTC2 and Anionic DSPS Lipid System is Influenced by pH, Temperature, and Salt Concentration Biophysical Journal. 106: 700a. DOI: 10.1016/J.Bpj.2013.11.3875  0.451
2013 Mui BL, Tam YK, Jayaraman M, Ansell SM, Du X, Tam YY, Lin PJ, Chen S, Narayanannair JK, Rajeev KG, Manoharan M, Akinc A, Maier MA, Cullis P, Madden TD, et al. Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles. Molecular Therapy. Nucleic Acids. 2: e139. PMID 24345865 DOI: 10.1038/Mtna.2013.66  0.445
2013 Rungta RL, Choi HB, Lin PJ, Ko RW, Ashby D, Nair J, Manoharan M, Cullis PR, Macvicar BA. Lipid Nanoparticle Delivery of siRNA to Silence Neuronal Gene Expression in the Brain. Molecular Therapy. Nucleic Acids. 2: e136. PMID 24301867 DOI: 10.1038/Mtna.2013.65  0.318
2013 Tam YY, Chen S, Cullis PR. Advances in Lipid Nanoparticles for siRNA Delivery. Pharmaceutics. 5: 498-507. PMID 24300520 DOI: 10.3390/Pharmaceutics5030498  0.407
2013 Maier MA, Jayaraman M, Matsuda S, Liu J, Barros S, Querbes W, Tam YK, Ansell SM, Kumar V, Qin J, Zhang X, Wang Q, Panesar S, Hutabarat R, Carioto M, ... ... Cullis P, et al. Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1570-8. PMID 23799535 DOI: 10.1038/Mt.2013.124  0.442
2013 Tam YY, Chen S, Zaifman J, Tam YK, Lin PJ, Ansell S, Roberge M, Ciufolini MA, Cullis PR. Small molecule ligands for enhanced intracellular delivery of lipid nanoparticle formulations of siRNA. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 665-74. PMID 23219877 DOI: 10.1016/J.Nano.2012.11.006  0.43
2013 Allen TM, Cullis PR. Liposomal drug delivery systems: from concept to clinical applications. Advanced Drug Delivery Reviews. 65: 36-48. PMID 23036225 DOI: 10.1016/J.Addr.2012.09.037  0.404
2013 Lin PJ, Tam YY, Hafez I, Sandhu A, Chen S, Ciufolini MA, Nabi IR, Cullis PR. Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 233-46. PMID 22698807 DOI: 10.1016/J.Nano.2012.05.019  0.467
2013 Mui BL, Tam YK, Jayaraman M, Ansell SM, Du X, Tam YYC, Lin PJC, Chen S, Narayanannair JK, Rajeev KG, Manoharan M, Akinc A, Maier MA, Cullis P, Madden TD, et al. Influence of polyethylene glycol lipid desorption rates on pharmacokinetics and pharmacodynamics of siRNA lipid nanoparticles Molecular Therapy - Nucleic Acids. 2. DOI: 10.1038/mtna.2013.66  0.332
2012 Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, et al. Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells. Molecular Therapy. Nucleic Acids. 1: e4. PMID 23344621 DOI: 10.1038/Mtna.2011.3  0.322
2012 Belliveau NM, Huft J, Lin PJ, Chen S, Leung AK, Leaver TJ, Wild AW, Lee JB, Taylor RJ, Tam YK, Hansen CL, Cullis PR. Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA. Molecular Therapy. Nucleic Acids. 1: e37. PMID 23344179 DOI: 10.1038/Mtna.2012.28  0.409
2012 Hope MJ, Bally MB, Webb G, Cullis PR. Production of large unilamellar vesicles by a rapid extrusion procedure: characterization of size distribution, trapped volume and ability to maintain a membrane potential. Biochimica Et Biophysica Acta. 812: 55-65. PMID 23008845 DOI: 10.1016/0005-2736(85)90521-8  0.397
2012 Leung AK, Hafez IM, Baoukina S, Belliveau NM, Zhigaltsev IV, Afshinmanesh E, Tieleman DP, Hansen CL, Hope MJ, Cullis PR. Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core. The Journal of Physical Chemistry. C, Nanomaterials and Interfaces. 116: 18440-18450. PMID 22962627 DOI: 10.1021/Jp303267Y  0.461
2012 Jayaraman M, Ansell SM, Mui BL, Tam YK, Chen J, Du X, Butler D, Eltepu L, Matsuda S, Narayanannair JK, Rajeev KG, Hafez IM, Akinc A, Maier MA, Tracy MA, ... Cullis PR, et al. Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo Angewandte Chemie - International Edition. 51: 8529-8533. PMID 22782619 DOI: 10.1002/Anie.201203263  0.444
2012 Zhigaltsev IV, Belliveau N, Hafez I, Leung AK, Huft J, Hansen C, Cullis PR. Bottom-up design and synthesis of limit size lipid nanoparticle systems with aqueous and triglyceride cores using millisecond microfluidic mixing. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 3633-40. PMID 22268499 DOI: 10.1021/La204833H  0.385
2012 Lee JB, Zhang K, Tam YY, Tam YK, Belliveau NM, Sung VY, Lin PJ, LeBlanc E, Ciufolini MA, Rennie PS, Cullis PR. Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo. International Journal of Cancer. Journal International Du Cancer. 131: E781-90. PMID 22095615 DOI: 10.1002/Ijc.27361  0.324
2012 Leung AKK, Hafez IM, Baoukina S, Belliveau NM, Zhigaltsev IV, Afshinmanesh E, Tieleman DP, Hansen CL, Hope MJ, Cullis PR. Correction to “Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core” The Journal of Physical Chemistry C. 116: 22104-22104. DOI: 10.1021/Jp3088786  0.398
2011 Basha G, Novobrantseva TI, Rosin N, Tam YYC, Hafez IM, Wong MK, Sugo T, Ruda VM, Qin J, Klebanov B, Ciufolini M, Akinc A, Tam YK, Hope MJ, Cullis PR. Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells Molecular Therapy. 19: 2186-2200. PMID 21971424 DOI: 10.1038/Mt.2011.190  0.427
2011 Geetha-Loganathan P, Nimmagadda S, Hafez I, Fu K, Cullis PR, Richman JM. Development of high-concentration lipoplexes for in vivo gene function studies in vertebrate embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 2108-19. PMID 21805533 DOI: 10.1002/Dvdy.22708  0.363
2010 Zhigaltsev IV, Winters G, Srinivasulu M, Crawford J, Wong M, Amankwa L, Waterhouse D, Masin D, Webb M, Harasym N, Heller L, Bally MB, Ciufolini MA, Cullis PR, Maurer N. Development of a weak-base docetaxel derivative that can be loaded into lipid nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 144: 332-40. PMID 20202473 DOI: 10.1016/J.Jconrel.2010.02.029  0.357
2010 Semple SC, Akinc A, Chen J, Sandhu AP, Mui BL, Cho CK, Sah DW, Stebbing D, Crosley EJ, Yaworski E, Hafez IM, Dorkin JR, Qin J, Lam K, Rajeev KG, ... ... Cullis PR, et al. Rational design of cationic lipids for siRNA delivery. Nature Biotechnology. 28: 172-6. PMID 20081866 DOI: 10.1038/Nbt.1602  0.451
2009 Cressman S, Dobson I, Lee JB, Tam YY, Cullis PR. Synthesis of a labeled RGD-lipid, its incorporation into liposomal nanoparticles, and their trafficking in cultured endothelial cells. Bioconjugate Chemistry. 20: 1404-11. PMID 19534457 DOI: 10.1021/Bc900041F  0.385
2009 Wilson KD, de Jong SD, Kazem M, Lall R, Hope MJ, Cullis PR, Tam YK. The combination of stabilized plasmid lipid particles and lipid nanoparticle encapsulated CpG containing oligodeoxynucleotides as a systemic genetic vaccine. The Journal of Gene Medicine. 11: 14-25. PMID 19003796 DOI: 10.1002/Jgm.1267  0.359
2008 Raney SG, Wilson KD, Sekirov L, Chikh G, de Jong SD, Cullis PR, Tam YK. The effect of circulation lifetime and drug-to-lipid ratio of intravenously administered lipid nanoparticles on the biodistribution and immunostimulatory activity of encapsulated CpG-ODN. Journal of Drug Targeting. 16: 564-77. PMID 18686126 DOI: 10.1080/10611860802228756  0.416
2008 Johnston MJ, Edwards K, Karlsson G, Cullis PR. Influence of drug-to-lipid ratio on drug release properties and liposome integrity in liposomal doxorubicin formulations. Journal of Liposome Research. 18: 145-57. PMID 18569449 DOI: 10.1080/08982100802129372  0.358
2008 Fenske DB, Chonn A, Cullis PR. Liposomal nanomedicines: an emerging field. Toxicologic Pathology. 36: 21-9. PMID 18337218 DOI: 10.1177/0192623307310960  0.377
2007 Wilson KD, Raney SG, Sekirov L, Chikh G, deJong SD, Cullis PR, Tam YK. Effects of intravenous and subcutaneous administration on the pharmacokinetics, biodistribution, cellular uptake and immunostimulatory activity of CpG ODN encapsulated in liposomal nanoparticles. International Immunopharmacology. 7: 1064-75. PMID 17570323 DOI: 10.1016/J.Intimp.2007.04.002  0.308
2007 de Jonge J, Leenhouts JM, Holtrop M, Schoen P, Scherrer P, Cullis PR, Wilschut J, Huckriede A. Cellular gene transfer mediated by influenza virosomes with encapsulated plasmid DNA. The Biochemical Journal. 405: 41-9. PMID 17355227 DOI: 10.1042/Bj20061756  0.347
2007 Johnston MJ, Semple SC, Klimuk SK, Ansell S, Maurer N, Cullis PR. Characterization of the drug retention and pharmacokinetic properties of liposomal nanoparticles containing dihydrosphingomyelin. Biochimica Et Biophysica Acta. 1768: 1121-7. PMID 17321495 DOI: 10.1016/J.Bbamem.2007.01.019  0.432
2007 Webb MS, Boman NL, Masin D, Yapp D, Ramsay E, Chiu GNC, Cullis PR, Bally MB. A cationic liposomal vincristine formulation with improved vincristine retention, extended circulation lifetime and increased anti-tumor activity Letters in Drug Design and Discovery. 4: 426-433. DOI: 10.2174/157018007781387782  0.435
2006 Johnston MJ, Semple SC, Klimuk SK, Edwards K, Eisenhardt ML, Leng EC, Karlsson G, Yanko D, Cullis PR. Therapeutically optimized rates of drug release can be achieved by varying the drug-to-lipid ratio in liposomal vincristine formulations. Biochimica Et Biophysica Acta. 1758: 55-64. PMID 16487476 DOI: 10.1016/J.Bbamem.2006.01.009  0.336
2006 Zhigaltsev IV, Maurer N, Edwards K, Karlsson G, Cullis PR. Formation of drug-arylsulfonate complexes inside liposomes: a novel approach to improve drug retention. Journal of Controlled Release : Official Journal of the Controlled Release Society. 110: 378-86. PMID 16318894 DOI: 10.1016/J.Jconrel.2005.10.011  0.347
2006 MacLachlan I, Cullis P. "Diffusible-PEG-lipid stabilized plasmid lipid particles". Advances in Genetics. 53: 157-88. PMID 16240993  0.317
2005 Ambegia E, Ansell S, Cullis P, Heyes J, Palmer L, MacLachlan I. Stabilized plasmid-lipid particles containing PEG-diacylglycerols exhibit extended circulation lifetimes and tumor selective gene expression. Biochimica Et Biophysica Acta. 1669: 155-163. PMID 15893518 DOI: 10.1016/J.Bbamem.2005.02.001  0.423
2005 Sandhu AP, Lam AM, Fenske DB, Palmer LR, Johnston M, Cullis PR. Calcium enhances the transfection potency of stabilized plasmid-lipid particles. Analytical Biochemistry. 341: 156-64. PMID 15866540 DOI: 10.1016/J.Ab.2005.02.033  0.685
2005 Zhigaltsev IV, Maurer N, Akhong QF, Leone R, Leng E, Wang J, Semple SC, Cullis PR. Liposome-encapsulated vincristine, vinblastine and vinorelbine: a comparative study of drug loading and retention. Journal of Controlled Release : Official Journal of the Controlled Release Society. 104: 103-11. PMID 15866338 DOI: 10.1016/J.Jconrel.2005.01.010  0.378
2005 Semple SC, Leone R, Wang J, Leng EC, Klimuk SK, Eisenhardt ML, Yuan ZN, Edwards K, Maurer N, Hope MJ, Cullis PR, Ahkong QF. Optimization and characterization of a sphingomyelin/cholesterol liposome formulation of vinorelbine with promising antitumor activity. Journal of Pharmaceutical Sciences. 94: 1024-38. PMID 15793796 DOI: 10.1002/Jps.20332  0.378
2005 Abraham SA, Waterhouse DN, Mayer LD, Cullis PR, Madden TD, Bally MB. The liposomal formulation of doxorubicin. Methods in Enzymology. 391: 71-97. PMID 15721375 DOI: 10.1016/S0076-6879(05)91004-5  0.37
2005 Waterhouse DN, Madden TD, Cullis PR, Bally MB, Mayer LD, Webb MS. Preparation, characterization, and biological analysis of liposomal formulations of vincristine. Methods in Enzymology. 391: 40-57. PMID 15721373 DOI: 10.1016/S0076-6879(05)91002-1  0.417
2005 Fenske DB, Cullis PR. Entrapment of small molecules and nucleic acid-based drugs in liposomes. Methods in Enzymology. 391: 7-40. PMID 15721372 DOI: 10.1016/S0076-6879(05)91001-X  0.456
2004 Chen T, McIntosh D, He Y, Kim J, Tirrell DA, Scherrer P, Fenske DB, Sandhu AP, Cullis PR. Alkylated derivatives of poly(ethylacrylic acid) can be inserted into preformed liposomes and trigger pH-dependent intracellular delivery of liposomal contents. Molecular Membrane Biology. 21: 385-93. PMID 15764368 DOI: 10.1080/09687860400010516  0.386
2004 Chen T, Palmer LR, Fenske DB, Lam AM, Wong KF, Cullis PR. Distal cationic poly(ethylene glycol) lipid conjugates in large unilamellar vesicles prepared by extrusion enhance liposomal cellular uptake. Journal of Liposome Research. 14: 155-73. PMID 15676124 DOI: 10.1081/Lpr-200033437  0.725
2004 Allen TM, Cullis PR. Drug delivery systems: entering the mainstream. Science (New York, N.Y.). 303: 1818-22. PMID 15031496 DOI: 10.1126/Science.1095833  0.355
2003 Palmer LR, Chen T, Lam AM, Fenske DB, Wong KF, MacLachlan I, Cullis PR. Transfection properties of stabilized plasmid-lipid particles containing cationic PEG lipids. Biochimica Et Biophysica Acta. 1611: 204-16. PMID 12659962 DOI: 10.1016/S0005-2736(03)00058-0  0.721
2002 Zhigaltsev IV, Maurer N, Wong KF, Cullis PR. Triggered release of doxorubicin following mixing of cationic and anionic liposomes. Biochimica Et Biophysica Acta. 1565: 129-35. PMID 12225861 DOI: 10.1016/S0005-2736(02)00543-6  0.405
2002 Gaucheron J, Wong T, Wong KF, Maurer N, Cullis PR. Synthesis and properties of novel tetraalkyl cationic lipids. Bioconjugate Chemistry. 13: 671-5. PMID 12009960 DOI: 10.1021/Bc0101259  0.437
2002 Fenske DB, MacLachlan I, Cullis PR. Stabilized plasmid-lipid particles: a systemic gene therapy vector. Methods in Enzymology. 346: 36-71. PMID 11883080 DOI: 10.1016/S0076-6879(02)46048-X  0.412
2001 Maurer N, Fenske DB, Cullis PR. Developments in liposomal drug delivery systems. Expert Opinion On Biological Therapy. 1: 923-47. PMID 11728226 DOI: 10.1517/14712598.1.6.923  0.359
2001 Hafez IM, Maurer N, Cullis PR. On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids. Gene Therapy. 8: 1188-96. PMID 11509950 DOI: 10.1038/Sj.Gt.3301506  0.48
2001 Fenske DB, Palmer LR, Chen T, Wong KF, Cullis PR. Cationic poly(ethyleneglycol) lipids incorporated into pre-formed vesicles enhance binding and uptake to BHK cells. Biochimica Et Biophysica Acta. 1512: 259-72. PMID 11406103 DOI: 10.1016/S0005-2736(01)00327-3  0.468
2001 Semple SC, Klimuk SK, Harasym TO, Dos Santos N, Ansell SM, Wong KF, Maurer N, Stark H, Cullis PR, Hope MJ, Scherrer P. Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures. Biochimica Et Biophysica Acta. 1510: 152-66. PMID 11342155 DOI: 10.1016/S0005-2736(00)00343-6  0.479
2001 Maurer N, Wong KF, Stark H, Louie L, McIntosh D, Wong T, Scherrer P, Semple SC, Cullis PR. Spontaneous entrapment of polynucleotides upon electrostatic interaction with ethanol-destabilized cationic liposomes. Biophysical Journal. 80: 2310-26. PMID 11325732 DOI: 10.1016/S0006-3495(01)76202-9  0.431
2001 Hafez IM, Cullis PR. Roles of lipid polymorphism in intracellular delivery. Advanced Drug Delivery Reviews. 47: 139-48. PMID 11311989 DOI: 10.1016/S0169-409X(01)00103-X  0.465
2000 Ansell SM, Harasym TO, Tardi PG, Buchkowsky SS, Bally MB, Cullis PR. Antibody conjugation methods for active targeting of liposomes. Methods in Molecular Medicine. 25: 51-68. PMID 21318840 DOI: 10.1385/1-59259-075-6:51  0.34
2000 Tam P, Monck M, Lee D, Ludkovski O, Leng EC, Clow K, Stark H, Scherrer P, Graham RW, Cullis PR. Stabilized plasmid-lipid particles for systemic gene therapy. Gene Therapy. 7: 1867-74. PMID 11110420 DOI: 10.1038/Sj.Gt.3301308  0.366
2000 Oja C, Tardi P, Schutze-Redelmeier M, Cullis PR. Doxorubicin entrapped within liposome-associated antigens results in a selective inhibition of the antibody response to the linked antigen. Biochimica Et Biophysica Acta. 1468: 31-40. PMID 11018649 DOI: 10.1016/S0005-2736(00)00178-4  0.306
2000 Hafez IM, Ansell S, Cullis PR. Tunable pH-sensitive liposomes composed of mixtures of cationic and anionic lipids. Biophysical Journal. 79: 1438-46. PMID 10969005 DOI: 10.1016/S0006-3495(00)76395-8  0.431
2000 Chen T, Wong KF, Fenske DB, Palmer LR, Cullis PR. Fluorescent-labeled poly(ethylene glycol) lipid conjugates with distal cationic headgroups. Bioconjugate Chemistry. 11: 433-7. PMID 10821661 DOI: 10.1021/Bc990171X  0.424
2000 Monck MA, Mori A, Lee D, Tam P, Wheeler JJ, Cullis PR, Scherrer P. Stabilized plasmid-lipid particles: pharmacokinetics and plasmid delivery to distal tumors following intravenous injection. Journal of Drug Targeting. 7: 439-52. PMID 10758914 DOI: 10.3109/10611860009102218  0.425
2000 Saravolac EG, Ludkovski O, Skirrow R, Ossanlou M, Zhang YP, Giesbrecht C, Thompson J, Thomas S, Stark H, Cullis PR, Scherrer P. Encapsulation of plasmid DNA in stabilized plasmid-lipid particles composed of different cationic lipid concentration for optimal transfection activity. Journal of Drug Targeting. 7: 423-37. PMID 10758913 DOI: 10.3109/10611860009102217  0.478
2000 Lam AM, Cullis PR. Calcium enhances the transfection potency of plasmid DNA-cationic liposome complexes. Biochimica Et Biophysica Acta. 1463: 279-90. PMID 10675506 DOI: 10.1016/S0005-2736(99)00219-9  0.677
2000 Hafez IM, Cullis PR. Cholesteryl hemisuccinate exhibits pH sensitive polymorphic phase behavior. Biochimica Et Biophysica Acta. 1463: 107-14. PMID 10631299 DOI: 10.1016/S0005-2736(99)00186-8  0.348
2000 Webb MS, Sarris AH, Cabanillas F, Mayer LD, Bally MB, Burge C, Cullis PR. Clinical and Preclinical Pharmacology of Liposomal Vincristine Journal of Liposome Research. 10: 501-512. DOI: 10.3109/08982100009031114  0.358
2000 Cullis PR. Commentary: Liposomes by Accident Journal of Liposome Research. 10: ix-xxiv. DOI: 10.3109/08982100009029380  0.344
1999 Schoen P, Chonn A, Cullis PR, Wilschut J, Scherrer P. Gene transfer mediated by fusion protein hemagglutinin reconstituted in cationic lipid vesicles. Gene Therapy. 6: 823-32. PMID 10505107 DOI: 10.1038/Sj.Gt.3300919  0.437
1999 Zhang YP, Sekirov L, Saravolac EG, Wheeler JJ, Tardi P, Clow K, Leng E, Sun R, Cullis PR, Scherrer P. Stabilized plasmid-lipid particles for regional gene therapy: formulation and transfection properties. Gene Therapy. 6: 1438-47. PMID 10467368 DOI: 10.1038/Sj.Gt.3300965  0.464
1999 Wheeler JJ, Palmer L, Ossanlou M, MacLachlan I, Graham RW, Zhang YP, Hope MJ, Scherrer P, Cullis PR. Stabilized plasmid-lipid particles: construction and characterization. Gene Therapy. 6: 271-81. PMID 10435112 DOI: 10.1038/Sj.Gt.3300821  0.415
1999 Mok KW, Lam AM, Cullis PR. Stabilized plasmid-lipid particles: factors influencing plasmid entrapment and transfection properties. Biochimica Et Biophysica Acta. 1419: 137-50. PMID 10407066 DOI: 10.1016/S0005-2736(99)00059-0  0.673
1999 Maurer N, Mori A, Palmer L, Monck MA, Mok KW, Mui B, Akhong QF, Cullis PR. Lipid-based systems for the intracellular delivery of genetic drugs. Molecular Membrane Biology. 16: 129-40. PMID 10332748 DOI: 10.1080/096876899294869  0.447
1999 Maurer-Spurej E, Wong KF, Maurer N, Fenske DB, Cullis PR. Factors influencing uptake and retention of amino-containing drugs in large unilamellar vesicles exhibiting transmembrane pH gradients. Biochimica Et Biophysica Acta. 1416: 1-10. PMID 9889298 DOI: 10.1016/S0005-2736(98)00204-1  0.401
1998 Cullis PR, Chonn A, Semple SC. Interactions of liposomes and lipid-based carrier systems with blood proteins: Relation to clearance behaviour in vivo. Advanced Drug Delivery Reviews. 32: 3-17. PMID 10837632 DOI: 10.1016/S0169-409X(97)00128-2  0.43
1998 Cullis PR, Chonn A. Recent advances in liposome technologies and their applications for systemic gene delivery. Advanced Drug Delivery Reviews. 30: 73-83. PMID 10837603 DOI: 10.1016/S0169-409X(97)00108-7  0.413
1998 Maurer N, Wong KF, Hope MJ, Cullis PR. Anomalous solubility behavior of the antibiotic ciprofloxacin encapsulated in liposomes: a 1H-NMR study. Biochimica Et Biophysica Acta. 1374: 9-20. PMID 9814848 DOI: 10.1016/S0005-2736(98)00125-4  0.355
1998 Cheung BC, Sun TH, Leenhouts JM, Cullis PR. Loading of doxorubicin into liposomes by forming Mn2+-drug complexes. Biochimica Et Biophysica Acta. 1414: 205-16. PMID 9804955 DOI: 10.1016/S0005-2736(98)00168-0  0.365
1998 Fenske DB, Wong KF, Maurer E, Maurer N, Leenhouts JM, Boman N, Amankwa L, Cullis PR. Ionophore-mediated uptake of ciprofloxacin and vincristine into large unilamellar vesicles exhibiting transmembrane ion gradients. Biochimica Et Biophysica Acta. 1414: 188-204. PMID 9804953 DOI: 10.1016/S0005-2736(98)00166-7  0.36
1998 Webb MS, Saxon D, Wong FM, Lim HJ, Wang Z, Bally MB, Choi LS, Cullis PR, Mayer LD. Comparison of different hydrophobic anchors conjugated to poly(ethylene glycol): effects on the pharmacokinetics of liposomal vincristine. Biochimica Et Biophysica Acta. 1372: 272-82. PMID 9675310 DOI: 10.1016/S0005-2736(98)00077-7  0.435
1998 Schmid SL, Cullis PR. Membrane sorting. Endosome marker is fat not fiction. Nature. 392: 135-6. PMID 9515957 DOI: 10.1038/32309  0.37
1998 Bally MB, Lim H, Cullis PR, Mayer LD. Controlling the Drug Delivery Attributes of Lipid-Based Drug Formulations Journal of Liposome Research. 8: 299-335. DOI: 10.3109/08982109809035537  0.364
1998 Mori A, Chonn A, Choi LS, Israels A, Monck MA, Cullis PR. Stabilization and Regulated Fusion of Liposomes Containing a Cationic Lipid Using Amphipathic Polyethyleneglycol Derivatives Journal of Liposome Research. 8: 195-211. DOI: 10.3109/08982109809035526  0.446
1997 Tardi PG, Swartz EN, Harasym TO, Cullis PR, Bally MB. An immune response to ovalbumin covalently coupled to liposomes is prevented when the liposomes used contain doxorubicin. Journal of Immunological Methods. 210: 137-48. PMID 9520297 DOI: 10.1016/S0022-1759(97)00178-6  0.343
1997 Mok KW, Cullis PR. Structural and fusogenic properties of cationic liposomes in the presence of plasmid DNA. Biophysical Journal. 73: 2534-45. PMID 9370447 DOI: 10.1016/S0006-3495(97)78282-1  0.426
1997 Harasym TO, Cullis PR, Bally MB. Intratumor distribution of doxorubicin following i.v. administration of drug encapsulated in egg phosphatidylcholine/cholesterol liposomes. Cancer Chemotherapy and Pharmacology. 40: 309-17. PMID 9225948 DOI: 10.1007/S002800050662  0.362
1997 Bailey AL, Monck MA, Cullis PR. pH-induced destabilization of lipid bilayers by a lipopeptide derived from influenza hemagglutinin. Biochimica Et Biophysica Acta. 1324: 232-44. PMID 9092710 DOI: 10.1016/S0005-2736(96)00228-3  0.427
1997 Bailey AL, Cullis PR. Membrane fusion with cationic liposomes: effects of target membrane lipid composition. Biochemistry. 36: 1628-34. PMID 9048546 DOI: 10.1021/Bi961173X  0.444
1997 Bailey AL, Cullis PR. Chapter 9 Liposome Fusion Current Topics in Membranes. 44: 359-373. DOI: 10.1016/S0070-2161(08)60213-0  0.448
1996 Tardi PG, Boman NL, Cullis PR. Liposomal doxorubicin. Journal of Drug Targeting. 4: 129-40. PMID 8959485 DOI: 10.3109/10611869609015970  0.311
1996 Lafleur M, Bloom M, Eikenberry EF, Gruner SM, Han Y, Cullis PR. Correlation between lipid plane curvature and lipid chain order. Biophysical Journal. 70: 2747-57. PMID 8744312 DOI: 10.1016/S0006-3495(96)79844-2  0.35
1996 Oja CD, Semple SC, Chonn A, Cullis PR. Influence of dose on liposome clearance: critical role of blood proteins. Biochimica Et Biophysica Acta. 1281: 31-7. PMID 8652601 DOI: 10.1016/0005-2736(96)00003-X  0.343
1996 Holland JW, Hui C, Cullis PR, Madden TD. Poly(ethylene glycol)--lipid conjugates regulate the calcium-induced fusion of liposomes composed of phosphatidylethanolamine and phosphatidylserine. Biochemistry. 35: 2618-24. PMID 8611565 DOI: 10.1021/Bi952000V  0.481
1996 Holland JW, Cullis PR, Madden TD. Poly(ethylene glycol)-lipid conjugates promote bilayer formation in mixtures of non-bilayer-forming lipids. Biochemistry. 35: 2610-7. PMID 8611564 DOI: 10.1021/Bi951999J  0.465
1996 Semple SC, Chonn A, Cullis PR. Influence of cholesterol on the association of plasma proteins with liposomes. Biochemistry. 35: 2521-5. PMID 8611555 DOI: 10.1021/Bi950414I  0.411
1996 Boman NL, Tron VA, Bally MB, Cullis PR. Vincristine-induced dermal toxicity is significantly reduced when the drug is given in liposomes. Cancer Chemotherapy and Pharmacology. 37: 351-5. PMID 8548881 DOI: 10.1007/S002800050396  0.317
1995 Chonn A, Cullis PR. Recent advances in liposomal drug-delivery systems. Current Opinion in Biotechnology. 6: 698-708. PMID 8527843 DOI: 10.1016/0958-1669(95)80115-4  0.347
1995 Mui BL, Döbereiner HG, Madden TD, Cullis PR. Influence of transbilayer area asymmetry on the morphology of large unilamellar vesicles. Biophysical Journal. 69: 930-41. PMID 8519993 DOI: 10.1016/S0006-3495(95)79967-2  0.305
1995 Longman SA, Cullis PR, Choi L, de Jong G, Bally MB. A two-step targeting approach for delivery of doxorubicin-loaded liposomes to tumour cells in vivo. Cancer Chemotherapy and Pharmacology. 36: 91-101. PMID 7767956 DOI: 10.1007/Bf00689191  0.352
1995 Harasym TO, Tardi P, Longman SA, Ansell SM, Bally MB, Cullis PR, Choi LS. Poly(ethylene glycol)-modified phospholipids prevent aggregation during covalent conjugation of proteins to liposomes. Bioconjugate Chemistry. 6: 187-94. PMID 7599262 DOI: 10.1021/Bc00032A006  0.427
1995 Chonn A, Semple SC, Cullis PR. Beta 2 glycoprotein I is a major protein associated with very rapidly cleared liposomes in vivo, suggesting a significant role in the immune clearance of "non-self" particles. The Journal of Biological Chemistry. 270: 25845-9. PMID 7592769 DOI: 10.1074/Jbc.270.43.25845  0.326
1995 Longman SA, Cullis PR, Bally MB. A model approach for assessing liposome targetingin vivo Drug Delivery. 2: 156-165. DOI: 10.3109/10717549509031365  0.337
1995 Cullis PR, Hope MJ. Liposomes, dimitri papahadjopoulos, and us Journal of Liposome Research. 5: 829-836. DOI: 10.3109/08982109509012684  0.406
1995 Boman NL, Bally MB, Cullis PR, Mayer LD, Webb MS. Encapsulation of vincristine in liposomes reduces its toxicity and improves its anti-tumor efficacy Journal of Liposome Research. 5: 523-541. DOI: 10.3109/08982109509010240  0.362
1994 Mayer LD, Nayar R, Thies RL, Boman NL, Cullis PR, Bally MB. Identification of vesicle properties that enhance the antitumour activity of liposomal vincristine against murine L1210 leukemia. Cancer Chemotherapy and Pharmacology. 33: 17-24. PMID 8269584 DOI: 10.1007/Bf00686017  0.426
1994 Bally MB, Masin D, Nayar R, Cullis PR, Mayer LD. Transfer of liposomal drug carriers from the blood to the peritoneal cavity of normal and ascitic tumor-bearing mice. Cancer Chemotherapy and Pharmacology. 34: 137-46. PMID 8194164 DOI: 10.1007/Bf00685931  0.391
1994 Devine DV, Wong K, Serrano K, Chonn A, Cullis PR. Liposome-complement interactions in rat serum: implications for liposome survival studies. Biochimica Et Biophysica Acta. 1191: 43-51. PMID 8155683 DOI: 10.1016/0005-2736(94)90231-3  0.352
1994 Chakrabarti AC, Clark-Lewis I, Cullis PR. Influence of charge, charge distribution, and hydrophobicity on the transport of short model peptides into liposomes in response to transmembrane pH gradients. Biochemistry. 33: 8479-85. PMID 8031781 DOI: 10.1021/Bi00194A012  0.321
1994 Parr MJ, Ansell SM, Choi LS, Cullis PR. Factors influencing the retention and chemical stability of poly(ethylene glycol)-lipid conjugates incorporated into large unilamellar vesicles. Biochimica Et Biophysica Acta. 1195: 21-30. PMID 7918562 DOI: 10.1016/0005-2736(94)90004-3  0.467
1994 Bailey AL, Cullis PR. Modulation of membrane fusion by asymmetric transbilayer distributions of amino lipids. Biochemistry. 33: 12573-80. PMID 7918482 DOI: 10.1021/Bi00208A007  0.427
1994 Mayer LD, Cullis PR, Bally MB. The Use of Transmembrane pH Gradient-Driven Drug Encapsulation in the Pharmacodynamic Evaluation of Liposomal Doxorubicin Journal of Liposome Research. 4: 529-553. DOI: 10.3109/08982109409037060  0.461
1993 Parr MJ, Bally MB, Cullis PR. The presence of GM1 in liposomes with entrapped doxorubicin does not prevent RES blockade. Biochimica Et Biophysica Acta. 1168: 249-52. PMID 8504161 DOI: 10.1016/0005-2760(93)90132-S  0.371
1993 Mui BL, Cullis PR, Evans EA, Madden TD. Osmotic properties of large unilamellar vesicles prepared by extrusion. Biophysical Journal. 64: 443-53. PMID 8457670 DOI: 10.1016/S0006-3495(93)81385-7  0.354
1993 Monck MA, Bloom M, Lafleur M, Lewis RN, McElhaney RN, Cullis PR. Evidence for two pools of cholesterol in the Acholeplasma laidlawii strain B membrane: a deuterium NMR and DSC study. Biochemistry. 32: 3081-8. PMID 8457569 DOI: 10.1021/Bi00063A020  0.42
1993 Fenske DB, Cullis PR. Acyl chain orientational order in large unilamellar vesicles: comparison with multilamellar liposomes: a 2H and 31P nuclear magnetic resonance study. Biophysical Journal. 64: 1482-91. PMID 8324185 DOI: 10.1016/S0006-3495(93)81515-7  0.31
1993 Harrigan PR, Wong KF, Redelmeier TE, Wheeler JJ, Cullis PR. Accumulation of doxorubicin and other lipophilic amines into large unilamellar vesicles in response to transmembrane pH gradients. Biochimica Et Biophysica Acta. 1149: 329-38. PMID 8323951 DOI: 10.1016/0005-2736(93)90218-O  0.449
1993 Boman NL, Mayer LD, Cullis PR. Optimization of the retention properties of vincristine in liposomal systems. Biochimica Et Biophysica Acta. 1152: 253-8. PMID 8218326 DOI: 10.1016/0005-2736(93)90256-Y  0.386
1993 Harrigan PR, Hope MJ, Redelmeier TE, Cullis PR. Determination of transmembrane pH gradients and membrane potentials in liposomes. Biophysical Journal. 63: 1336-45. PMID 1477283 DOI: 10.1016/S0006-3495(92)81711-3  0.362
1992 Chonn A, Semple SC, Cullis PR. Separation of large unilamellar liposomes from blood components by a spin column procedure: towards identifying plasma proteins which mediate liposome clearance in vivo. Biochimica Et Biophysica Acta. 1070: 215-22. PMID 1751529 DOI: 10.1016/0005-2736(91)90167-7  0.322
1992 Chakrabarti AC, Veiro JA, Wong NS, Wheeler JJ, Cullis PR. Generation and characterization of iron- and barium-loaded liposomes. Biochimica Et Biophysica Acta. 1108: 233-9. PMID 1637848 DOI: 10.1016/0005-2736(92)90030-P  0.343
1992 Fenske DB, Cullis PR. Chemical exchange between lamellar and non-lamellar lipid phases. A one- and two-dimensional 31P-NMR study. Biochimica Et Biophysica Acta. 1108: 201-9. PMID 1637844 DOI: 10.1016/0005-2736(92)90026-I  0.342
1992 Eastman SJ, Hope MJ, Wong KF, Cullis PR. Influence of phospholipid asymmetry on fusion between large unilamellar vesicles. Biochemistry. 31: 4262-8. PMID 1567871 DOI: 10.1021/Bi00132A016  0.419
1992 Wilschut J, Scholma J, Eastman SJ, Hope MJ, Cullis PR. Ca(2+)-induced fusion of phospholipid vesicles containing free fatty acids: modulation by transmembrane pH gradients. Biochemistry. 31: 2629-36. PMID 1547206 DOI: 10.1021/Bi00125A001  0.346
1992 Kitson N, Monck M, Wong K, Thewalt J, Cullis P. The influence of cholesterol 3-sulphate on phase behaviour and hydrocarbon order in model membrane systems. Biochimica Et Biophysica Acta. 1111: 127-133. PMID 1390858 DOI: 10.1016/0005-2736(92)90282-Q  0.362
1992 Monck MA, Bloom M, Lafleur M, Lewis RN, McElhaney RN, Cullis PR. Influence of lipid composition on the orientational order in Acholeplasma laidlawii strain B membranes: a deuterium NMR study. Biochemistry. 31: 10037-43. PMID 1390762 DOI: 10.1021/Bi00156A025  0.406
1992 Chonn A, Cullis PR. Ganglioside GM1and Hydrophilic Polymers Increase Liposome Circulation Times by Inhibiting the Association of Blood Proteins Journal of Liposome Research. 2: 397-410. DOI: 10.3109/08982109209010217  0.325
1991 Bally MB, Nayar R, Masin D, Cullis PR, Mayer LD. Studies on the myelosuppressive activity of doxorubicin entrapped in liposomes. Cancer Chemotherapy and Pharmacology. 27: 13-9. PMID 2245488 DOI: 10.1007/Bf00689270  0.36
1991 Cullis PR, Bally MB, Madden TD, Mayer LD, Hope MJ. pH gradients and membrane transport in liposomal systems. Trends in Biotechnology. 9: 268-72. PMID 1367566 DOI: 10.1016/0167-7799(91)90088-Y  0.381
1991 Cullis PR, Hope MJ. Chapter 1 Physical properties and functional roles of lipids in membranes New Comprehensive Biochemistry. 20: 1-41. DOI: 10.1016/S0167-7306(08)60329-4  0.412
1990 Loughrey HC, Choi LS, Cullis PR, Bally MB. Optimized procedures for the coupling of proteins to liposomes. Journal of Immunological Methods. 132: 25-35. PMID 2391438 DOI: 10.1016/0022-1759(90)90394-B  0.346
1990 Mayer LD, Tai LC, Bally MB, Mitilenes GN, Ginsberg RS, Cullis PR. Characterization of liposomal systems containing doxorubicin entrapped in response to pH gradients. Biochimica Et Biophysica Acta. 1025: 143-51. PMID 2364073 DOI: 10.1016/0005-2736(90)90091-2  0.451
1990 Madden TD, Janoff AS, Cullis PR. Incorporation of amphotericin B into large unilamellar vesicles composed of phosphatidylcholine and phosphatidylglycerol. Chemistry and Physics of Lipids. 52: 189-98. PMID 2340597 DOI: 10.1016/0009-3084(90)90114-7  0.431
1990 Bally MB, Nayar R, Masin D, Hope MJ, Cullis PR, Mayer LD. Liposomes with entrapped doxorubicin exhibit extended blood residence times. Biochimica Et Biophysica Acta. 1023: 133-9. PMID 2317492 DOI: 10.1016/0005-2736(90)90018-J  0.422
1990 Lafleur M, Cullis PR, Fine B, Bloom M. Comparison of the orientational order of lipid chains in the Lα and HII phases Biochemistry®. 29: 8325-8333. PMID 2252892 DOI: 10.1021/Bi00488A018  0.359
1990 Thies RL, Cowens DW, Cullis PR, Bally MB, Mayer LD. Method for rapid separation of liposome-associated doxorubicin from free doxorubicin in plasma. Analytical Biochemistry. 188: 65-71. PMID 2221370 DOI: 10.1016/0003-2697(90)90528-H  0.378
1990 Mayer LD, Bally MB, Cullis PR, Wilson SL, Emerman JT. Comparison of free and liposome encapsulated doxorubicin tumor drug uptake and antitumor efficacy in the SC115 murine mammary tumor. Cancer Letters. 53: 183-90. PMID 2208078 DOI: 10.1016/0304-3835(90)90212-G  0.315
1990 Loughrey HC, Wong KF, Choi LS, Cullis PR, Bally MB. Protein-liposome conjugates with defined size distributions. Biochimica Et Biophysica Acta. 1028: 73-81. PMID 2207121 DOI: 10.1016/0005-2736(90)90267-R  0.345
1990 Lafleur M, Bloom M, Cullis PR. Lipid polymorphism and hydrocarbon order Biochemistry and Cell Biology. 68: 1-8. PMID 2190614 DOI: 10.1139/O90-001  0.39
1990 Veiro JA, Cullis PR. A novel method for the efficient entrapment of calcium in large unilamellar phospholipid vesicles. Biochimica Et Biophysica Acta. 1025: 109-15. PMID 2114930 DOI: 10.1016/0005-2736(90)90197-V  0.308
1990 Lafleur M, Cullis PR, Bloom M. Modulation of the orientational order profile of the lipid acyl chain in the Lα phase European Biophysics Journal. 19: 55-62. PMID 2073890 DOI: 10.1007/Bf00185086  0.331
1990 Madden TD, Harrigan PR, Tai LC, Bally MB, Mayer LD, Redelmeier TE, Loughrey HC, Tilcock CP, Reinish LW, Cullis PR. The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey. Chemistry and Physics of Lipids. 53: 37-46. PMID 1972352 DOI: 10.1016/0009-3084(90)90131-A  0.389
1990 Harrigan PR, Madden TD, Cullis PR. Protection of liposomes during dehydration or freezing. Chemistry and Physics of Lipids. 52: 139-49. PMID 1690089 DOI: 10.1016/0009-3084(90)90157-M  0.433
1990 Mayer LD, Bally MB, Cullis PR. Strategies for Optimizing Liposomal Doxorubicin Journal of Liposome Research. 1: 463-480. DOI: 10.3109/08982109009036008  0.462
1990 Boni LT, Perkins WR, Minchey SR, Bolcsak LE, Gruner SM, Cullis PR, Hope MJ, Janoff AS. Polymorphic phase behavior of alpha-tocopherol hemisuccinate Chemistry and Physics of Lipids. 54: 193-203. DOI: 10.1016/0009-3084(90)90012-G  0.32
1989 Madden TD, Tilcock CP, Wong K, Cullis PR. Spontaneous vesiculation of large multilamellar vesicles composed of saturated phosphatidylcholine and phosphatidylglycerol mixtures. Biochemistry. 27: 8724-30. PMID 3242602 DOI: 10.1021/Bi00424A006  0.349
1989 Tilcock C, Unger E, Cullis P, MacDougall P. Liposomal Gd-DTPA: preparation and characterization of relaxivity. Radiology. 171: 77-80. PMID 2928549 DOI: 10.1148/Radiology.171.1.2928549  0.407
1989 Tilcock C, Chin R, Veiro J, Cullis P, Fisher D. Detection of surface charge-related properties in model membrane systems by aqueous two-phase partition. Biochimica Et Biophysica Acta. 986: 167-171. PMID 2819094 DOI: 10.1016/0005-2736(89)90287-3  0.397
1989 Unger EC, MacDougall P, Cullis P, Tilcock C. Liposomal Gd-DTPA: effect of encapsulation on enhancement of hepatoma model by MRI. Magnetic Resonance Imaging. 7: 417-423. PMID 2811620 DOI: 10.1016/0730-725X(89)90491-8  0.344
1989 Hope MJ, Redelmeier TE, Wong KF, Rodrigueza W, Cullis PR. Phospholipid asymmetry in large unilamellar vesicles induced by transmembrane pH gradients. Biochemistry. 28: 4181-7. PMID 2765480 DOI: 10.1021/Bi00436A009  0.38
1989 Eastman SJ, Wilschut J, Cullis PR, Hope MJ. Intervesicular exchange of lipids with weak acid and weak base characteristics: influence of transmembrane pH gradients. Biochimica Et Biophysica Acta. 981: 178-84. PMID 2730899 DOI: 10.1016/0005-2736(89)90026-6  0.42
1989 Hope MJ, Wong KF, Cullis PR. Freeze-fracture of lipids and model membrane systems. Journal of Electron Microscopy Technique. 13: 277-87. PMID 2681573 DOI: 10.1002/Jemt.1060130403  0.382
1989 Lafleur M, Fine B, Sternin E, Cullis PR, Bloom M. Smoothed orientational order profile of lipid bilayers by 2H-nuclear magnetic resonance Biophysical Journal. 56: 1037-1041. PMID 2605294 DOI: 10.1016/S0006-3495(89)82749-3  0.352
1989 Balazsovits JA, Mayer LD, Bally MB, Cullis PR, McDonell M, Ginsberg RS, Falk RE. Analysis of the effect of liposome encapsulation on the vesicant properties, acute and cardiac toxicities, and antitumor efficacy of doxorubicin. Cancer Chemotherapy and Pharmacology. 23: 81-6. PMID 2491964 DOI: 10.1007/Bf00273522  0.338
1989 Tilcock C, Cullis P, Dempsey T, Youens BN, Fisher D. Aqueous two-phase polymer partitioning of lipid vesicles of defined size and composition. Biochimica Et Biophysica Acta. 979: 208-214. PMID 2466484 DOI: 10.1016/0005-2736(89)90436-7  0.387
1989 Ostro MJ, Cullis PR. Use of liposomes as injectable-drug delivery systems American Journal of Health-System Pharmacy. 46: 1576-1588. DOI: 10.1093/Ajhp/46.8.1576  0.465
1989 Cullis P, Mayer L, Bally M, Madden T, Hope M. Generating and loading of liposomal systems for drug-delivery applications Advanced Drug Delivery Reviews. 3: 267-282. DOI: 10.1016/0169-409X(89)90024-0  0.363
1989 Nayar R, Hope MJ, Cullis PR. Generation of large unilamellar vesicles from long-chain saturated phosphatidylcholines by extrusion technique Biochimica Et Biophysica Acta (Bba) - Biomembranes. 986: 200-206. DOI: 10.1016/0005-2736(89)90468-9  0.381
1988 Janoff AS, Boni LT, Popescu MC, Minchey SR, Cullis PR, Madden TD, Taraschi T, Gruner SM, Shyamsunder E, Tate MW. Unusual lipid structures selectively reduce the toxicity of amphotericin B. Proceedings of the National Academy of Sciences of the United States of America. 85: 6122-6. PMID 3413081 DOI: 10.1073/Pnas.85.16.6122  0.389
1988 Tilcock CP, Cullis PR, Gruner SM. Calcium-induced phase separation phenomena in multicomponent unsaturated lipid mixtures. Biochemistry. 27: 1415-20. PMID 3365396 DOI: 10.1021/Bi00405A004  0.385
1988 Nayar R, Tilcock CP, Hope MJ, Cullis PR, Schroit AJ. N-succinyldioleoylphosphatidylethanolamine: structural preferences in pure and mixed model membranes. Biochimica Et Biophysica Acta. 937: 31-41. PMID 3334845 DOI: 10.1016/0005-2736(88)90224-6  0.389
1987 Wong KF, Parmar YI, Mayer LD, Pritchard PH, Cullis PR. Detection of protein-free lipoprotein analogues with an apolar lipid core by freeze-etch electron microscopy. Biochimica Et Biophysica Acta. 921: 411-4. PMID 3651497 DOI: 10.1016/0005-2760(87)90044-0  0.374
1987 Madden TD, Hope MJ, Cullis PR. Modelling the biological membrane. Biochemical Society Transactions. 15: 75-7. PMID 3556743 DOI: 10.1042/Bst0150075  0.312
1987 Sparks DL, Frohlich J, Cullis P, Pritchard PH. Cholesteryl ester transfer activity in plasma measured by using solid-phase-bound high-density lipoprotein Clinical Chemistry. 33: 390-393. DOI: 10.1093/Clinchem/33.3.390  0.327
1986 Mayer LD, Bally MB, Cullis PR. Uptake of adriamycin into large unilamellar vesicles in response to a pH gradient. Biochimica Et Biophysica Acta. 857: 123-6. PMID 3964703 DOI: 10.1016/0005-2736(86)90105-7  0.398
1986 Richards RL, Habbersett RC, Scher I, Janoff AS, Schieren HP, Mayer LD, Cullis PR, Alving CR. Influence of vesicle size on complement-dependent immune damage to liposomes. Biochimica Et Biophysica Acta. 855: 223-30. PMID 3753881 DOI: 10.1016/0005-2736(86)90168-9  0.324
1986 Mayer LD, Bally MB, Hope MJ, Cullis PR. Techniques for encapsulating bioactive agents into liposomes. Chemistry and Physics of Lipids. 40: 333-45. PMID 3742676 DOI: 10.1016/0009-3084(86)90077-0  0.376
1986 Cullis PR, Hope MJ, Tilcock CP. Lipid polymorphism and the roles of lipids in membranes. Chemistry and Physics of Lipids. 40: 127-44. PMID 3742670 DOI: 10.1016/0009-3084(86)90067-8  0.447
1986 Cullis PR, de Kruijff B, Verkleij AJ, Hope MJ. Lipid polymorphism and membrane fusion. Biochemical Society Transactions. 14: 242-5. PMID 3709946 DOI: 10.1042/Bst0140242  0.391
1986 Mayer LD, Hope MJ, Cullis PR. Vesicles of variable sizes produced by a rapid extrusion procedure. Biochimica Et Biophysica Acta. 858: 161-8. PMID 3707960 DOI: 10.1016/0005-2736(86)90302-0  0.361
1986 RAUCH J, TANNENBAUM M, TANNENBAUM H, RAMELSON H, CULLIS PR, TILCOCK CPS, HOPE MJ, JANOFF AS. Hybridoma Lupus Anticoagulants Distinguish between Bilayer and Nonbilayer Phase Lipid Systems Annals of the New York Academy of Sciences. 475: 366-369. DOI: 10.1111/J.1749-6632.1986.Tb20896.X  0.398
1986 Hope M, Bally M, Mayer L, Janoff A, Cullis P. Generation of multilamellar and unilamellar phospholipid vesicles Chemistry and Physics of Lipids. 40: 89-107. DOI: 10.1016/0009-3084(86)90065-4  0.362
1985 Madden TD, Bally MB, Hope MJ, Cullis PR, Schieren HP, Janoff AS. Protection of large unilamellar vesicles by trehalose during dehydration: retention of vesicle contents. Biochimica Et Biophysica Acta. 817: 67-74. PMID 4005259 DOI: 10.1016/0005-2736(85)90069-0  0.365
1985 Mayer LD, Hope MJ, Cullis PR, Janoff AS. Solute distributions and trapping efficiencies observed in freeze-thawed multilamellar vesicles. Biochimica Et Biophysica Acta. 817: 193-6. PMID 4005257 DOI: 10.1016/0005-2736(85)90084-7  0.34
1985 Mayer LD, Bally MB, Hope MJ, Cullis PR. Uptake of antineoplastic agents into large unilamellar vesicles in response to a membrane potential. Biochimica Et Biophysica Acta. 816: 294-302. PMID 3839135 DOI: 10.1016/0005-2736(85)90497-3  0.443
1985 Madden TD, Cullis PR. Preparation of reconstituted cytochrome oxidase vesicles with defined trans-membrane protein orientations employing a cytochrome c affinity column. Biochimica Et Biophysica Acta. 808: 219-24. PMID 2990553 DOI: 10.1016/0005-2728(85)90002-7  0.344
1985 Bally MB, Hope MJ, Van Echteld CJA, Cullis PR. Uptake of safranine and other lipophilic cations into model membrane systems in response to a membrane potential Bba - Biomembranes. 812: 66-76. DOI: 10.1016/0005-2736(85)90522-X  0.377
1984 Sommerman EF, Pritchard PH, Cullis PR. 125I labelled inulin: a convenient marker for deposition of liposomal contents in vivo. Biochemical and Biophysical Research Communications. 122: 319-24. PMID 6743334 DOI: 10.1016/0006-291X(84)90477-7  0.319
1984 Tilcock CP, Bally MB, Farren SB, Cullis PR, Gruner SM. Cation-dependent segregation phenomena and phase behavior in model membrane systems containing phosphatidylserine: influence of cholesterol and acyl chain composition. Biochemistry. 23: 2696-703. PMID 6466608 DOI: 10.1021/Bi00307A025  0.427
1984 Madden TD, Hope MJ, Cullis PR. Influence of vesicle size and oxidase content on respiratory control in reconstituted cytochrome oxidase vesicles. Biochemistry. 23: 1413-8. PMID 6326801 DOI: 10.1021/Bi00302A012  0.392
1984 Tilcock C, Hope M, Cullis P. Influence of cholesterol esters of varying unsaturation on the polymorphic phase preferences of egg phosphatidylethanolamine Chemistry and Physics of Lipids. 35: 363-370. DOI: 10.1016/0009-3084(84)90078-1  0.397
1983 Tilcock CP, Bally MB, Farren SB, Cullis PR. Influence of cholesterol on the structural preferences of dioleoylphosphatidylethanolamine-dioleoylphosphatidylcholine systems: a phosphorus-31 and deuterium nuclear magnetic resonance study. Biochemistry. 21: 4596-601. PMID 7138819 DOI: 10.1021/Bi00262A013  0.353
1983 Nayar R, Hope MJ, Cullis PR. Phospholipids as adjuncts for calcium ion stimulated release of chromaffin granule contents: implications for mechanisms of exocytosis. Biochemistry. 21: 4583-9. PMID 7138818 DOI: 10.1021/Bi00262A011  0.414
1983 Farren SB, Hope MJ, Cullis PR. Polymorphic phase preferences of phosphatidic acid: A 31P and 2H NMR study. Biochemical and Biophysical Research Communications. 111: 675-82. PMID 6838577 DOI: 10.1016/0006-291X(83)90359-5  0.373
1983 Hope MJ, Walker DC, Cullis PR. Ca2+ and pH induced fusion of small unilamellar vesicles consisting of phosphatidylethanolamine and negatively charged phospholipids: a freeze fracture study. Biochemical and Biophysical Research Communications. 110: 15-22. PMID 6838506 DOI: 10.1016/0006-291X(83)91253-6  0.406
1983 Madden TD, Hope MJ, Cullis PR. Lipid requirements for coupled cytochrome oxidase vesicles. Biochemistry. 22: 1970-4. PMID 6303398 DOI: 10.1021/Bi00277A036  0.431
1982 Hornby AP, Cullis PR. Influence of local and neutral anaesthetics on the polymorphic phase preferences of egg yolk phosphatidylethanolamine. Biochimica Et Biophysica Acta. 647: 285-92. PMID 7295728 DOI: 10.1016/0005-2736(81)90256-X  0.345
1982 Nayar R, Schmid SL, Hope MJ, Cullis PR. Structural preferences of phosphatidylinositol and phosphatidylinositol-phosphatidylethanolamine model membranes. Influence of Ca2+ and Mg2+. Biochimica Et Biophysica Acta. 688: 169-76. PMID 7093273 DOI: 10.1016/0005-2736(82)90592-2  0.365
1982 Madden TD, Cullis PR. Stabilization of bilayer structure for unsaturated phosphatidylethanolamines by detergents. Biochimica Et Biophysica Acta. 684: 149-53. PMID 7055552 DOI: 10.1016/0005-2736(82)90061-X  0.384
1982 Hemminga MA, Cullis PR. 31P NMR studies of oriented phospholipid multilayers Journal of Magnetic Resonance (1969). 47: 307-323. DOI: 10.1016/0022-2364(82)90122-6  0.327
1981 Cullis PR, de Kruijff B, Hope MJ, Nayar R, Schmid SL. Phospholipids and membrane transport. Canadian Journal of Biochemistry. 58: 1091-100. PMID 7459674 DOI: 10.1139/O80-147  0.375
1981 Hope MJ, Cullis PR. The role of nonbilayer lipid structures in the fusion of human erythrocytes induced by lipid fusogens. Biochimica Et Biophysica Acta. 640: 82-90. PMID 7213694 DOI: 10.1016/0005-2736(81)90533-2  0.436
1981 Tilcock CP, Cullis PR. The polymorphic phase behaviour of mixed phosphatidylserine-phosphatidylethanolamine model systems as detected by 31P-NMR. Biochimica Et Biophysica Acta. 641: 189-201. PMID 7194114 DOI: 10.1016/0005-2736(81)90583-6  0.356
1981 Farren SB, Cullis PR. Polymorphism of phosphatidylglycerol-phosphatidylethanolamine model membrane systems: a 31p NMR study. Biochemical and Biophysical Research Communications. 97: 182-91. PMID 7192983 DOI: 10.1016/S0006-291X(80)80152-5  0.338
1981 de Kruijff B, Cullis PR. Cytochrome c specifically induces non-bilayer structures in cardiolipin-containing model membranes. Biochimica Et Biophysica Acta. 602: 477-90. PMID 6254562 DOI: 10.1016/0005-2736(80)90327-2  0.365
1981 de Kruijff B, Verkleij AJ, van Echteld CJA, Gerritsen WJ, Mombers CA, Noordam PC, de Gier J, Cullis PR. STRUCTURAL AND FUNCTIONAL ASPECTS OF NON-BILAYER LIPIDS IN MEMBRANES Biochemical Society Transactions. 9: 113P-113P. DOI: 10.1042/Bst009113Pa  0.395
1980 Burnell EE, Cullis PR, de Kruijff B. Effects of tumbling and lateral diffusion on phosphatidylcholine model membrane 31P-NMR lineshapes Bba - Biomembranes. 603: 63-69. PMID 7448188 DOI: 10.1016/0005-2736(80)90391-0  0.34
1980 de Kruijff B, Morris GA, Cullis PR. Application of 31P-NMR saturation transfer techniques to investigate phospholipid motion and organization in model and biological membranes. Biochimica Et Biophysica Acta. 598: 206-11. PMID 7417428 DOI: 10.1016/0005-2736(80)90281-3  0.337
1980 de Kruijff B, Cullis PR. The influence of poly(L-lysine) on phospholipid polymorphism. Evidence that electrostatic polypeptide-phospholipid interactions can modulate bilayer/non-bilayer transitions. Biochimica Et Biophysica Acta. 601: 235-40. PMID 7407163 DOI: 10.1016/0005-2736(80)90528-3  0.325
1980 Cullis PR, de Kruijff B, Hope MJ, Nayar R, Rietveld A, Verkleij AJ. Structural properties of phospholipids in the rat liver inner mitochondrial membrane. Biochimica Et Biophysica Acta. 600: 625-35. PMID 7407135 DOI: 10.1016/0005-2736(80)90466-6  0.376
1980 Verkleij AJ, van Echteld CJ, Gerritsen WJ, Cullis PR, de Kruijff B. The lipidic particle as an intermediate structure in membrane fusion processes and bilayer to hexagonal HII transitions. Biochimica Et Biophysica Acta. 600: 620-4. PMID 7407134 DOI: 10.1016/0005-2736(80)90465-4  0.414
1980 de Kruijff B, Reitveld A, Cullis PR. 31P-NMR studies on membrane phospholipids in microsomes, rat liver slices and intact perfused rat liver. Biochimica Et Biophysica Acta. 600: 343-57. PMID 7407118 DOI: 10.1016/0005-2736(80)90438-1  0.313
1980 Cullis PR, Hope MJ. The bilayer stabilizing role of sphingomyelin in the presence of cholesterol: a 31P NMR study. Biochimica Et Biophysica Acta. 597: 533-42. PMID 7378401 DOI: 10.1016/0005-2736(80)90225-4  0.408
1980 Hope MJ, Cullis PR. Effects of divalent cations and pH on phosphatidylserine model membranes: a 31P NMR study. Biochemical and Biophysical Research Communications. 92: 846-52. PMID 7189120 DOI: 10.1016/0006-291X(80)90780-9  0.354
1980 Hope MJ, Cullis PR. The bilayer stability of inner monolayer lipids from the human erythrocyte. Febs Letters. 107: 323-6. PMID 510542 DOI: 10.1016/0014-5793(79)80399-3  0.446
1980 Cullis PR, de Kruijff B. Lipid polymorphism and the functional roles of lipids in biological membranes. Biochimica Et Biophysica Acta. 559: 399-420. PMID 391283 DOI: 10.1016/0304-4157(79)90012-1  0.427
1980 de Kruijff B, Cullis P, Verkleij A. Non-bilayer lipid structures in model and biological membranes Trends in Biochemical Sciences. 5: 79-81. DOI: 10.1016/0968-0004(80)90074-2  0.433
1979 Verkleij AJ, Mombers C, Gerritsen WJ, Leunissen-Bijvelt L, Cullis PR. Fusion of phospholipid vesicles in association with the appearance of lipidic particles as visualized by freeze fracturing. Biochimica Et Biophysica Acta. 555: 358-61. PMID 573139 DOI: 10.1016/0005-2736(79)90175-5  0.376
1979 Cullis PR, Verkleij AJ. Modulation of membrane structure by Ca2+ and dibucaine as detected by 31P NMR. Biochimica Et Biophysica Acta. 552: 546-51. PMID 571738 DOI: 10.1016/0005-2736(79)90200-1  0.366
1979 Cullis PR, Verkleij AJ, Ververgaert PH. Polymorphic phase behaviour of cardiolipin as detected by 31P NMR and freeze-fracture techniques. Effects of calcium, dibucaine and chlorpromazine. Biochimica Et Biophysica Acta. 513: 11-20. PMID 102344 DOI: 10.1016/0005-2736(78)90107-4  0.317
1979 Cullis PR, de Kruijff B. The polymorphic phase behaviour of phosphatidylethanolamines of natural and synthetic origin. A 31P NMR study. Biochimica Et Biophysica Acta. 513: 31-42. PMID 31173 DOI: 10.1016/0005-2736(78)90109-8  0.359
1978 Cullis PR, Grathwohl C. Hydrocarbon phase transitions and lipid-protein interactions in the erythrocyte membrane. A 31P NMR and fluorescence study. Biochimica Et Biophysica Acta. 471: 213-26. PMID 921979 DOI: 10.1016/0005-2736(77)90251-6  0.428
1978 de Kruijff B, van den Besselaar AM, Cullis PR, van den Bosch H, van Deenen LL. Evidence for isotropic motion of phospholipids in liver microsomal membranes. A 31P NMR study. Biochimica Et Biophysica Acta. 514: 1-8. PMID 718902 DOI: 10.1016/0005-2736(78)90072-X  0.367
1978 Cullis PR, Van Dijck PWM, De Kruijff B, De Gier J. Effects of cholesterol on the properties of equimolar mixtures of synthetic phosphatidylethanolamine and phosphatidylcholine. A 31P NMR and differential scanning calorimetry study Bba - Biomembranes. 513: 21-30. PMID 718888 DOI: 10.1016/0005-2736(78)90108-6  0.361
1978 Cullis PR, De Kruijff B. Polymorphic phase behaviour of lipid mixtures as detected by 31P NMR. Evidence that cholesterol may destabilize bilayer structure in membrane systems containing phosphatidylethanolamine. Biochimica Et Biophysica Acta. 507: 207-18. PMID 626732 DOI: 10.1016/0005-2736(78)90417-0  0.418
1978 Cullis PR, Hope MJ. Effects of fusogenic agent on membrane structure of erythrocyte ghosts and the mechanism of membrane fusion Nature. 271: 672-674. PMID 625336 DOI: 10.1038/271672A0  0.42
1977 Cullis PR. Lateral diffusion rates of phosphatidylcholine in vesicle membranes: effects of cholesterol and hydrocarbon phase transitions. Febs Letters. 70: 223-8. PMID 992064 DOI: 10.1016/0014-5793(76)80762-4  0.362
1976 Cullis PR, De Kruyff B, Richards RE. Factors affecting the motion of the polar headgroup in phospholipid bilayers. A 31P NMR study of unsonicated phosphatidylcholine liposomes. Biochimica Et Biophysica Acta. 426: 433-46. PMID 1268206 DOI: 10.1016/0005-2736(76)90388-6  0.305
1976 de Kruijff B, Cullis PR, Radda GK. Differential scanning calorimetry and 31P NMR studies on sonicated and unsonicated phosphatidylcholine liposomes. Biochimica Et Biophysica Acta. 406: 6-20. PMID 1242108 DOI: 10.1016/0005-2736(75)90038-3  0.444
1976 De Kruijff B, Cullis PR, Radda GK. Outside-inside distributions and sizes of mixed phosphatidylcholine-cholesterol vesicles. Biochimica Et Biophysica Acta. 436: 729-40. PMID 952917 DOI: 10.1016/0005-2736(76)90402-8  0.401
1976 Cullis PR, De Kruyff B. 31P NMR studies of unsonicated aqueous dispersions of neutral and acidic phospholipids. Effects of phase transitions, p2H and divalent cations on the motion in the phosphate region of the polar headgroup. Biochimica Et Biophysica Acta. 436: 523-40. PMID 952909 DOI: 10.1016/0005-2736(76)90438-7  0.314
1976 De Kruijff B, Cullis PR, Radda GK, Richards RE. Phosphorus nuclear magnetic resonance of Acholeplasma laidlawii cell membranes and derived liposomes. Biochimica Et Biophysica Acta. 419: 411-24. PMID 174728 DOI: 10.1016/0005-2736(76)90255-8  0.411
1975 McLaughlin AC, Cullis PR, Hemminga MA, Hoult DI, Radda GK, Ritchie GA, Seeley PJ, Richards RE. Application of 31P NMR to model and biological membrane systems. Febs Letters. 57: 213-8. PMID 1175790 DOI: 10.1016/0014-5793(75)80719-8  0.323
1975 McLaughlin AC, Cullis PR, Berden JA, Richards RE. 31P NMR of Phospholipid membranes: Effects of chemical and anisotropy at high magnetic field strengths Journal of Magnetic Resonance (1969). 20: 146-165. DOI: 10.1016/0022-2364(75)90162-6  0.31
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