Paola Arlotta - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Brown J, Quadrato G, Arlotta P. Studying the Brain in a Dish: 3D Cell Culture Models of Human Brain Development and Disease. Current Topics in Developmental Biology. 129: 99-122. PMID 29801532 DOI: 10.1016/bs.ctdb.2018.03.002  1
2018 Farahany NA, Greely HT, Hyman S, Koch C, Grady C, Pașca SP, Sestan N, Arlotta P, Bernat JL, Ting J, Lunshof JE, Iyer EPR, Hyun I, Capestany BH, Church GM, et al. The ethics of experimenting with human brain tissue. Nature. 556: 429-432. PMID 29691509 DOI: 10.1038/d41586-018-04813-x  0.6
2017 Quadrato G, Arlotta P. Present and future of modeling human brain development in 3D organoids. Current Opinion in Cell Biology. 49: 47-52. PMID 29227864 DOI: 10.1016/j.ceb.2017.11.010  1
2017 Kim J, Hughes EG, Shetty AS, Arlotta P, Goff LA, Bergles DE, Brown SP. Changes in the excitability of neocortical neurons in a mouse model of amyotrophic lateral sclerosis are not specific to corticospinal neurons and are modulated by advancing disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28821643 DOI: 10.1523/JNEUROSCI.0811-17.2017  0.92
2017 Quadrato G, Nguyen T, Macosko EZ, Sherwood JL, Min Yang S, Berger DR, Maria N, Scholvin J, Goldman M, Kinney JP, Boyden ES, Lichtman JW, Williams ZM, McCarroll SA, Arlotta P. Cell diversity and network dynamics in photosensitive human brain organoids. Nature. PMID 28445462 DOI: 10.1038/nature22047  1
2016 Quadrato G, Brown J, Arlotta P. The promises and challenges of human brain organoids as models of neuropsychiatric disease. Nature Medicine. PMID 27783065 DOI: 10.1038/nm.4214  1
2016 Quadrato G, Zhang AC, Arlotta P. Stressed out? Healing Tips for Newly Reprogrammed Neurons. Cell Stem Cell. 18: 297-9. PMID 26942845 DOI: 10.1016/j.stem.2016.02.008  1
2016 Chen HH, Arlotta P. Seq-ing the cortex one neuron at a time. Nature Neuroscience. 19: 179-81. PMID 26814585 DOI: 10.1038/nn.4230  0.64
2015 Ye Z, Mostajo-Radji MA, Brown JR, Rouaux C, Tomassy GS, Hensch TK, Arlotta P. Instructing Perisomatic Inhibition by Direct Lineage Reprogramming of Neocortical Projection Neurons. Neuron. 88: 475-83. PMID 26539889 DOI: 10.1016/j.neuron.2015.10.006  1
2015 Tomassy GS, Dershowitz LB, Arlotta P. Diversity Matters: A Revised Guide to Myelination. Trends in Cell Biology. PMID 26442841 DOI: 10.1016/j.tcb.2015.09.002  1
2015 Lodato S, Arlotta P. Generating Neuronal Diversity in the Mammalian Cerebral Cortex. Annual Review of Cell and Developmental Biology. PMID 26359774 DOI: 10.1146/annurev-cellbio-100814-125353  1
2015 Goff LA, Groff AF, Sauvageau M, Trayes-Gibson Z, Sanchez-Gomez DB, Morse M, Martin RD, Elcavage LE, Liapis SC, Gonzalez-Celeiro M, Plana O, Li E, Gerhardinger C, Tomassy GS, Arlotta P, et al. Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain. Proceedings of the National Academy of Sciences of the United States of America. PMID 26034286 DOI: 10.1073/pnas.1411263112  1
2015 Harris J, Tomassy GS, Arlotta P. Building blocks of the cerebral cortex: from development to the dish. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 25926310 DOI: 10.1002/wdev.192  1
2015 Smith KA, Arlotta P, Watt FM, Solomon SL. Seven actionable strategies for advancing women in science, engineering, and medicine. Cell Stem Cell. 16: 221-4. PMID 25748929 DOI: 10.1016/j.stem.2015.02.012  1
2015 Molyneaux BJ, Goff LA, Brettler AC, Chen HH, Brown JR, Hrvatin S, Rinn JL, Arlotta P. DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex. Neuron. 85: 275-88. PMID 25556833 DOI: 10.1016/j.neuron.2014.12.024  1
2015 Lodato S, Shetty AS, Arlotta P. Cerebral cortex assembly: generating and reprogramming projection neuron diversity. Trends in Neurosciences. 38: 117-25. PMID 25529141 DOI: 10.1016/j.tins.2014.11.003  1
2014 Lodato S, Molyneaux BJ, Zuccaro E, Goff LA, Chen HH, Yuan W, Meleski A, Takahashi E, Mahony S, Rinn JL, Gifford DK, Arlotta P. Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nature Neuroscience. 17: 1046-54. PMID 24997765 DOI: 10.1038/nn.3757  1
2014 Arlotta P, Berninger B. Brains in metamorphosis: reprogramming cell identity within the central nervous system. Current Opinion in Neurobiology. 27: 208-14. PMID 24800935 DOI: 10.1016/j.conb.2014.04.007  1
2014 Tomassy GS, Berger DR, Chen HH, Kasthuri N, Hayworth KJ, Vercelli A, Seung HS, Lichtman JW, Arlotta P. Distinct profiles of myelin distribution along single axons of pyramidal neurons in the neocortex. Science (New York, N.Y.). 344: 319-24. PMID 24744380 DOI: 10.1126/science.1249766  1
2014 Amamoto R, Arlotta P. Development-inspired reprogramming of the mammalian central nervous system. Science (New York, N.Y.). 343: 1239882. PMID 24482482 DOI: 10.1126/science.1239882  1
2013 Sauvageau M, Goff LA, Lodato S, Bonev B, Groff AF, Gerhardinger C, Sanchez-Gomez DB, Hacisuleyman E, Li E, Spence M, Liapis SC, Mallard W, Morse M, Swerdel MR, D'Ecclessis MF, ... ... Arlotta P, et al. Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Elife. 2: e01749. PMID 24381249 DOI: 10.7554/eLife.01749  1
2013 Amamoto R, Arlotta P. Reshaping the brain: direct lineage conversion in the nervous system. F1000prime Reports. 5: 33. PMID 24049637 DOI: 10.12703/P5-33  1
2013 Zuccaro E, Arlotta P. The quest for myelin in the adult brain. Nature Cell Biology. 15: 572-5. PMID 23644465 DOI: 10.1038/ncb2750  1
2013 Rouaux C, Arlotta P. Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo. Nature Cell Biology. 15: 214-21. PMID 23334497 DOI: 10.1038/ncb2660  1
2013 Tomassy GS, Lodato S, Arlotta P. A sip of GABA for the cerebral cortex. Neuron. 77: 1-3. PMID 23312509 DOI: 10.1016/j.neuron.2012.12.026  1
2013 MacDonald JL, Fame RM, Azim E, Shnider SJ, Molyneaux BJ, Arlotta P, Macklis JD. Specification of Cortical Projection Neurons: Transcriptional Mechanisms Comprehensive Developmental Neuroscience: Patterning and Cell Type Specification in the Developing Cns and Pns. 475-502. DOI: 10.1016/B978-0-12-397265-1.00098-8  1
2012 Cappello S, Böhringer CR, Bergami M, Conzelmann KK, Ghanem A, Tomassy GS, Arlotta P, Mainardi M, Allegra M, Caleo M, van Hengel J, Brakebusch C, Götz M. A radial glia-specific role of RhoA in double cortex formation. Neuron. 73: 911-24. PMID 22405202 DOI: 10.1016/j.neuron.2011.12.030  1
2012 Rouaux C, Bhai S, Arlotta P. Programming and reprogramming neuronal subtypes in the central nervous system. Developmental Neurobiology. 72: 1085-98. PMID 22378700 DOI: 10.1002/dneu.22018  1
2012 Sohur US, Arlotta P, Macklis JD. Developmental Controls are Re-Expressed during Induction of Neurogenesis in the Neocortex of Young Adult Mice. Frontiers in Neuroscience. 6: 12. PMID 22347158 DOI: 10.3389/fnins.2012.00012  1
2012 López-Bendito G, Arlotta P. Cell replacement therapies for nervous system regeneration. Developmental Neurobiology. 72: 145-52. PMID 21557508 DOI: 10.1002/dneu.20897  1
2011 Lodato S, Tomassy GS, De Leonibus E, Uzcategui YG, Andolfi G, Armentano M, Touzot A, Gaztelu JM, Arlotta P, Menendez de la Prida L, Studer M. Loss of COUP-TFI alters the balance between caudal ganglionic eminence- and medial ganglionic eminence-derived cortical interneurons and results in resistance to epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4650-62. PMID 21430164 DOI: 10.1523/JNEUROSCI.6580-10.2011  1
2011 Lodato S, Rouaux C, Quast KB, Jantrachotechatchawan C, Studer M, Hensch TK, Arlotta P. Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex. Neuron. 69: 763-79. PMID 21338885 DOI: 10.1016/j.neuron.2011.01.015  1
2011 Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P. Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nature Biotechnology. 29: 149-53. PMID 21248753 DOI: 10.1038/nbt.1775  0.92
2010 Rouaux C, Arlotta P. Fezf2 directs the differentiation of corticofugal neurons from striatal progenitors in vivo. Nature Neuroscience. 13: 1345-7. PMID 20953195 DOI: 10.1038/nn.2658  1
2010 Tomassy GS, Lodato S, Trayes-Gibson Z, Arlotta P. Development and regeneration of projection neuron subtypes of the cerebral cortex. Science Progress. 93: 151-69. PMID 20681320 DOI: 10.3184/003685010X12705764469952  1
2010 Shoemaker LD, Arlotta P. Untangling the cortex: Advances in understanding specification and differentiation of corticospinal motor neurons. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 32: 197-206. PMID 20108227 DOI: 10.1002/bies.200900114  1
2009 Molyneaux BJ, Arlotta P, Fame RM, MacDonald JL, MacQuarrie KL, Macklis JD. Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12343-54. PMID 19793993 DOI: 10.1523/JNEUROSCI.6108-08.2009  1
2008 Lai T, Jabaudon D, Molyneaux BJ, Azim E, Arlotta P, Menezes JR, Macklis JD. SOX5 controls the sequential generation of distinct corticofugal neuron subtypes. Neuron. 57: 232-47. PMID 18215621 DOI: 10.1016/j.neuron.2007.12.023  1
2008 Arlotta P, Molyneaux BJ, Jabaudon D, Yoshida Y, Macklis JD. Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 622-32. PMID 18199763 DOI: 10.1523/JNEUROSCI.2986-07.2008  1
2008 Lai T, Jabaudon D, Molyneaux BJ, Azim E, Arlotta P, Menezes JRL, Macklis JD. SOX5 Controls the Sequential Generation of Distinct Corticofugal Neuron Subtypes (DOI:10.1016/j.neuron.2007.12.023) Neuron. 57: 626. DOI: 10.1016/j.neuron.2008.02.001  1
2007 Molyneaux BJ, Arlotta P, Macklis JD. Molecular development of corticospinal motor neuron circuitry. Novartis Foundation Symposium. 288: 3-15; discussion 15-. PMID 18494249 DOI: 10.1002/9780470994030.ch2  1
2007 Gao X, Arlotta P, Macklis JD, Chen J. Conditional knock-out of beta-catenin in postnatal-born dentate gyrus granule neurons results in dendritic malformation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14317-25. PMID 18160639 DOI: 10.1523/JNEUROSCI.3206-07.2007  1
2007 Molyneaux BJ, Arlotta P, Menezes JR, Macklis JD. Neuronal subtype specification in the cerebral cortex. Nature Reviews. Neuroscience. 8: 427-37. PMID 17514196 DOI: 10.1038/nrn2151  1
2005 Molyneaux BJ, Arlotta P, Hirata T, Hibi M, Macklis JD. Fezl is required for the birth and specification of corticospinal motor neurons. Neuron. 47: 817-31. PMID 16157277 DOI: 10.1016/j.neuron.2005.08.030  1
2005 Arlotta P, Macklis JD. Archeo-cell biology: carbon dating is not just for pots and dinosaurs. Cell. 122: 4-6. PMID 16009125 DOI: 10.1016/j.cell.2005.06.037  1
2005 Arlotta P, Molyneaux BJ, Chen J, Inoue J, Kominami R, Macklis JD. Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo. Neuron. 45: 207-21. PMID 15664173 DOI: 10.1016/j.neuron.2004.12.036  1
2004 Emsley JG, Mitchell BD, Magavi SS, Arlotta P, Macklis JD. The repair of complex neuronal circuitry by transplanted and endogenous precursors. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 1: 452-71. PMID 15717047 DOI: 10.1602/neurorx.1.4.452  1
2004 Mitchell BD, Emsley JG, Magavi SS, Arlotta P, Macklis JD. Constitutive and induced neurogenesis in the adult mammalian brain: manipulation of endogenous precursors toward CNS repair. Developmental Neuroscience. 26: 101-17. PMID 15711054 DOI: 10.1159/000082131  1
2004 Catapano LA, Arlotta P, Cage TA, Macklis JD. Stage-specific and opposing roles of BDNF, NT-3 and bFGF in differentiation of purified callosal projection neurons toward cellular repair of complex circuitry. The European Journal of Neuroscience. 19: 2421-34. PMID 15128396 DOI: 10.1111/j.0953-816X.2004.03303.x  1
2004 Emsley JG, Arlotta P, Macklis JD. Star-cross'd neurons: astroglial effects on neural repair in the adult mammalian CNS. Trends in Neurosciences. 27: 238-40. PMID 15111002 DOI: 10.1016/j.tins.2004.02.008  1
2003 Arlotta P, Magavi SS, Macklis JD. Induction of adult neurogenesis: molecular manipulation of neural precursors in situ. Annals of the New York Academy of Sciences. 991: 229-36. PMID 12846990  1
2003 Arlotta P, Magavi SS, Macklis JD. Molecular manipulation of neural precursors in situ: induction of adult cortical neurogenesis. Experimental Gerontology. 38: 173-82. PMID 12543275 DOI: 10.1016/S0531-5565(02)00156-0  1
2002 Arlotta P, Miyazaki D, Copeland NG, Gilbert DJ, Jenkins NA, Ono SJ. Murine NFX.1: isolation and characterization of its messenger RNA, mapping of its chromosomal location and assessment of its developmental expression. Immunology. 106: 173-81. PMID 12047746 DOI: 10.1046/j.1365-2567.2002.01416.x  1
2001 Liu F, Chau KY, Arlotta P, Ono SJ. The HMG I proteins: dynamic roles in gene activation, development, and tumorigenesis. Immunologic Research. 24: 13-29. PMID 11485207 DOI: 10.1385/IR:24:1:13  1
2000 Fedoseyeva EV, Boisgérault F, Anosova NG, Wollish WS, Arlotta P, Jensen PE, Ono SJ, Benichou G. CD4+ T cell responses to self- and mutated p53 determinants during tumorigenesis in mice. Journal of Immunology (Baltimore, Md. : 1950). 164: 5641-51. PMID 10820239  1
2000 Arlotta P, Tai AK, Manfioletti G, Clifford C, Jay G, Ono SJ. Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas. The Journal of Biological Chemistry. 275: 14394-400. PMID 10747931 DOI: 10.1074/jbc.M000564200  1
1999 Chau K, Arlotta P, Patel UA, Crane-Robinson C, Manfioletti G, Ono SJ. A novel downstream positive regulatory element mediating transcription of the human high mobility group (HMG) I-C gene. Febs Letters. 457: 429-36. PMID 10471823 DOI: 10.1016/S0014-5793(99)01100-X  1
1997 Arlotta P, Rustighi A, Mantovani F, Manfioletti G, Giancotti V, Tell G, Damante G. High mobility group I proteins interfere with the homeodomains binding to DNA. The Journal of Biological Chemistry. 272: 29904-10. PMID 9368066 DOI: 10.1074/jbc.272.47.29904  1
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