Paola Arlotta - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Arlotta P, Chen F, Lodato S, Margrie TW, Nowakowski TJ, Pederson T, Rico B. Dissecting cellular diversity of cortical GABAergic cells across multiple modalities: A turning point in neuronal taxonomy. Faculty Reviews. 11: 13. PMID 35719130 DOI: 10.12703/r-01-000009  0.549
2022 Paulsen B, Velasco S, Kedaigle AJ, Pigoni M, Quadrato G, Deo AJ, Adiconis X, Uzquiano A, Sartore R, Yang SM, Simmons SK, Symvoulidis P, Kim K, Tsafou K, Podury A, ... ... Arlotta P, et al. Autism genes converge on asynchronous development of shared neuron classes. Nature. PMID 35110736 DOI: 10.1038/s41586-021-04358-6  0.825
2021 Matho KS, Huilgol D, Galbavy W, He M, Kim G, An X, Lu J, Wu P, Di Bella DJ, Shetty AS, Palaniswamy R, Hatfield J, Raudales R, Narasimhan A, Gamache E, ... ... Arlotta P, et al. Genetic dissection of the glutamatergic neuron system in cerebral cortex. Nature. 598: 182-187. PMID 34616069 DOI: 10.1038/s41586-021-03955-9  0.771
2020 Yang SM, Michel K, Jokhi V, Nedivi E, Arlotta P. Neuron class-specific responses govern adaptive myelin remodeling in the neocortex. Science (New York, N.Y.). 370. PMID 33335032 DOI: 10.1126/science.abd2109  0.415
2020 Jin X, Simmons SK, Guo A, Shetty AS, Ko M, Nguyen L, Jokhi V, Robinson E, Oyler P, Curry N, Deangeli G, Lodato S, Levin JZ, Regev A, Zhang F, ... Arlotta P, et al. In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes. Science (New York, N.Y.). 370. PMID 33243861 DOI: 10.1126/science.aaz6063  0.809
2020 Velasco S, Paulsen B, Arlotta P. 3D Brain Organoids: Studying Brain Development and Disease Outside the Embryo. Annual Review of Neuroscience. 43: 375-389. PMID 32640930 DOI: 10.1146/annurev-neuro-070918-050154  0.585
2020 Harris JM, Wang AY, Boulanger-Weill J, Santoriello C, Foianini S, Lichtman JW, Zon LI, Arlotta P. Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects. Developmental Cell. 53: 577-588.e7. PMID 32516597 DOI: 10.1016/J.Devcel.2020.05.009  0.401
2019 Amamoto R, Zuccaro E, Curry NC, Khurana S, Chen HH, Cepko CL, Arlotta P. FIN-Seq: transcriptional profiling of specific cell types from frozen archived tissue of the human central nervous system. Nucleic Acids Research. PMID 31728515 DOI: 10.1093/nar/gkz968  0.331
2019 Velasco S, Kedaigle AJ, Simmons SK, Nash A, Rocha M, Quadrato G, Paulsen B, Nguyen L, Adiconis X, Regev A, Levin JZ, Arlotta P. Individual brain organoids reproducibly form cell diversity of the human cerebral cortex. Nature. PMID 31168097 DOI: 10.1038/S41586-019-1289-X  0.785
2019 Zonouzi M, Berger D, Jokhi V, Kedaigle A, Lichtman J, Arlotta P. Individual Oligodendrocytes Show Bias for Inhibitory Axons in the Neocortex. Cell Reports. 27: 2799-2808.e3. PMID 31167127 DOI: 10.1016/j.celrep.2019.05.018  0.812
2019 Arlotta P, Paşca SP. Cell diversity in the human cerebral cortex: from the embryo to brain organoids. Current Opinion in Neurobiology. 56: 194-198. PMID 31051421 DOI: 10.1016/J.Conb.2019.03.001  0.368
2019 Adam Y, Kim JJ, Lou S, Zhao Y, Xie ME, Brinks D, Wu H, Mostajo-Radji MA, Kheifets S, Parot V, Chettih S, Williams KJ, Gmeiner B, Farhi SL, Madisen L, ... ... Arlotta P, et al. Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics. Nature. PMID 31043747 DOI: 10.1038/S41586-019-1166-7  0.783
2018 Brown J, Quadrato G, Arlotta P. Studying the Brain in a Dish: 3D Cell Culture Models of Human Brain Development and Disease. Current Topics in Developmental Biology. 129: 99-122. PMID 29801532 DOI: 10.1016/Bs.Ctdb.2018.03.002  0.738
2018 Nehme R, Zuccaro E, Ghosh SD, Li C, Sherwood JL, Pietilainen O, Barrett LE, Limone F, Worringer KA, Kommineni S, Zang Y, Cacchiarelli D, Meissner A, Adolfsson R, Haggarty S, ... ... Arlotta P, et al. Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission. Cell Reports. 23: 2509-2523. PMID 29791859 DOI: 10.1016/J.Celrep.2018.04.066  0.575
2018 Arlotta P. Organoids required! A new path to understanding human brain development and disease. Nature Methods. 15: 27-29. PMID 29298289 DOI: 10.1038/nmeth.4557  0.319
2017 Quadrato G, Arlotta P. Present and future of modeling human brain development in 3D organoids. Current Opinion in Cell Biology. 49: 47-52. PMID 29227864 DOI: 10.1016/J.Ceb.2017.11.010  0.738
2017 Kim J, Hughes EG, Shetty AS, Arlotta P, Goff LA, Bergles DE, Brown SP. Changes in the excitability of neocortical neurons in a mouse model of amyotrophic lateral sclerosis are not specific to corticospinal neurons and are modulated by advancing disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28821643 DOI: 10.1523/Jneurosci.0811-17.2017  0.784
2017 Quadrato G, Nguyen T, Macosko EZ, Sherwood JL, Min Yang S, Berger DR, Maria N, Scholvin J, Goldman M, Kinney JP, Boyden ES, Lichtman JW, Williams ZM, McCarroll SA, Arlotta P. Cell diversity and network dynamics in photosensitive human brain organoids. Nature. PMID 28445462 DOI: 10.1038/Nature22047  0.84
2017 Quadrato G, Sherwood JL, Arlotta P. Long-term culture and electrophysiological characterization of human brain organoids Protocol Exchange. DOI: 10.1038/Protex.2017.049  0.721
2016 Quadrato G, Brown J, Arlotta P. The promises and challenges of human brain organoids as models of neuropsychiatric disease. Nature Medicine. PMID 27783065 DOI: 10.1038/Nm.4214  0.728
2016 Amamoto R, Huerta VG, Takahashi E, Dai G, Grant AK, Fu Z, Arlotta P. Adult axolotls can regenerate original neuronal diversity in response to brain injury. Elife. 5. PMID 27156560 DOI: 10.7554/eLife.13998  0.566
2016 Quadrato G, Zhang AC, Arlotta P. Stressed out? Healing Tips for Newly Reprogrammed Neurons. Cell Stem Cell. 18: 297-9. PMID 26942845 DOI: 10.1016/J.Stem.2016.02.008  0.824
2016 Chen HH, Arlotta P. Seq-ing the cortex one neuron at a time. Nature Neuroscience. 19: 179-81. PMID 26814585 DOI: 10.1038/nn.4230  0.563
2016 Amamoto R, Huerta VGL, Takahashi E, Dai G, Grant AK, Fu Z, Arlotta P. Author response: Adult axolotls can regenerate original neuronal diversity in response to brain injury Elife. DOI: 10.7554/Elife.13998.025  0.448
2015 Arlotta P, Hobert O. Homeotic Transformations of Neuronal Cell Identities. Trends in Neurosciences. PMID 26596501 DOI: 10.1016/J.Tins.2015.10.005  0.476
2015 Ye Z, Mostajo-Radji MA, Brown JR, Rouaux C, Tomassy GS, Hensch TK, Arlotta P. Instructing Perisomatic Inhibition by Direct Lineage Reprogramming of Neocortical Projection Neurons. Neuron. 88: 475-83. PMID 26539889 DOI: 10.1016/J.Neuron.2015.10.006  0.86
2015 Tomassy GS, Dershowitz LB, Arlotta P. Diversity Matters: A Revised Guide to Myelination. Trends in Cell Biology. PMID 26442841 DOI: 10.1016/j.tcb.2015.09.002  0.465
2015 Lodato S, Arlotta P. Generating Neuronal Diversity in the Mammalian Cerebral Cortex. Annual Review of Cell and Developmental Biology. PMID 26359774 DOI: 10.1146/Annurev-Cellbio-100814-125353  0.849
2015 Goff LA, Groff AF, Sauvageau M, Trayes-Gibson Z, Sanchez-Gomez DB, Morse M, Martin RD, Elcavage LE, Liapis SC, Gonzalez-Celeiro M, Plana O, Li E, Gerhardinger C, Tomassy GS, Arlotta P, et al. Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain. Proceedings of the National Academy of Sciences of the United States of America. PMID 26034286 DOI: 10.1073/Pnas.1411263112  0.367
2015 Harris J, Tomassy GS, Arlotta P. Building blocks of the cerebral cortex: from development to the dish. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 25926310 DOI: 10.1002/Wdev.192  0.325
2015 Molyneaux BJ, Goff LA, Brettler AC, Chen HH, Brown JR, Hrvatin S, Rinn JL, Arlotta P. DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex. Neuron. 85: 275-88. PMID 25556833 DOI: 10.1016/J.Neuron.2014.12.024  0.848
2015 Lodato S, Shetty AS, Arlotta P. Cerebral cortex assembly: generating and reprogramming projection neuron diversity. Trends in Neurosciences. 38: 117-25. PMID 25529141 DOI: 10.1016/J.Tins.2014.11.003  0.852
2014 Lodato S, Molyneaux BJ, Zuccaro E, Goff LA, Chen HH, Yuan W, Meleski A, Takahashi E, Mahony S, Rinn JL, Gifford DK, Arlotta P. Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nature Neuroscience. 17: 1046-54. PMID 24997765 DOI: 10.1038/Nn.3757  0.857
2014 Arlotta P, Berninger B. Brains in metamorphosis: reprogramming cell identity within the central nervous system. Current Opinion in Neurobiology. 27: 208-14. PMID 24800935 DOI: 10.1016/J.Conb.2014.04.007  0.598
2014 Tomassy GS, Berger DR, Chen HH, Kasthuri N, Hayworth KJ, Vercelli A, Seung HS, Lichtman JW, Arlotta P. Distinct profiles of myelin distribution along single axons of pyramidal neurons in the neocortex. Science (New York, N.Y.). 344: 319-24. PMID 24744380 DOI: 10.1126/Science.1249766  0.697
2014 Amamoto R, Arlotta P. Development-inspired reprogramming of the mammalian central nervous system. Science (New York, N.Y.). 343: 1239882. PMID 24482482 DOI: 10.1126/science.1239882  0.321
2013 Sauvageau M, Goff LA, Lodato S, Bonev B, Groff AF, Gerhardinger C, Sanchez-Gomez DB, Hacisuleyman E, Li E, Spence M, Liapis SC, Mallard W, Morse M, Swerdel MR, D'Ecclessis MF, ... ... Arlotta P, et al. Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Elife. 2: e01749. PMID 24381249 DOI: 10.7554/Elife.01749  0.75
2013 Amamoto R, Arlotta P. Reshaping the brain: direct lineage conversion in the nervous system. F1000prime Reports. 5: 33. PMID 24049637 DOI: 10.12703/P5-33  0.411
2013 Zuccaro E, Arlotta P. The quest for myelin in the adult brain. Nature Cell Biology. 15: 572-5. PMID 23644465 DOI: 10.1038/ncb2750  0.359
2013 Rouaux C, Arlotta P. Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo. Nature Cell Biology. 15: 214-21. PMID 23334497 DOI: 10.1038/Ncb2660  0.853
2013 Tomassy GS, Lodato S, Arlotta P. A sip of GABA for the cerebral cortex. Neuron. 77: 1-3. PMID 23312509 DOI: 10.1016/J.Neuron.2012.12.026  0.728
2013 Tomassy GS, Lodato S, Arlotta P. ErratumA Sip of GABA for the Cerebral Cortex Neuron. DOI: 10.1016/J.Neuron.2013.02.019  0.711
2013 MacDonald JL, Fame RM, Azim E, Shnider SJ, Molyneaux BJ, Arlotta P, Macklis JD. Specification of Cortical Projection Neurons: Transcriptional Mechanisms Comprehensive Developmental Neuroscience: Patterning and Cell Type Specification in the Developing Cns and Pns. 475-502. DOI: 10.1016/B978-0-12-397265-1.00098-8  0.825
2012 Cappello S, Böhringer CR, Bergami M, Conzelmann KK, Ghanem A, Tomassy GS, Arlotta P, Mainardi M, Allegra M, Caleo M, van Hengel J, Brakebusch C, Götz M. A radial glia-specific role of RhoA in double cortex formation. Neuron. 73: 911-24. PMID 22405202 DOI: 10.1016/J.Neuron.2011.12.030  0.558
2012 Rouaux C, Bhai S, Arlotta P. Programming and reprogramming neuronal subtypes in the central nervous system. Developmental Neurobiology. 72: 1085-98. PMID 22378700 DOI: 10.1002/Dneu.22018  0.786
2012 Sohur US, Arlotta P, Macklis JD. Developmental Controls are Re-Expressed during Induction of Neurogenesis in the Neocortex of Young Adult Mice. Frontiers in Neuroscience. 6: 12. PMID 22347158 DOI: 10.3389/fnins.2012.00012  0.845
2012 López-Bendito G, Arlotta P. Cell replacement therapies for nervous system regeneration. Developmental Neurobiology. 72: 145-52. PMID 21557508 DOI: 10.1002/dneu.20897  0.522
2012 Lodato S, Rouaux C, Arlotta P. ISDN2012_0263: Molecular development of projection neuron types and building of local microcircuitry in the cerebral cortex International Journal of Developmental Neuroscience. 30: 634-634. DOI: 10.1016/J.Ijdevneu.2012.10.086  0.842
2011 Lodato S, Tomassy GS, De Leonibus E, Uzcategui YG, Andolfi G, Armentano M, Touzot A, Gaztelu JM, Arlotta P, Menendez de la Prida L, Studer M. Loss of COUP-TFI alters the balance between caudal ganglionic eminence- and medial ganglionic eminence-derived cortical interneurons and results in resistance to epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4650-62. PMID 21430164 DOI: 10.1523/Jneurosci.6580-10.2011  0.777
2011 Lodato S, Rouaux C, Quast KB, Jantrachotechatchawan C, Studer M, Hensch TK, Arlotta P. Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex. Neuron. 69: 763-79. PMID 21338885 DOI: 10.1016/J.Neuron.2011.01.015  0.869
2011 Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P. Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nature Biotechnology. 29: 149-53. PMID 21248753 DOI: 10.1038/Nbt.1775  0.731
2010 Rouaux C, Arlotta P. Fezf2 directs the differentiation of corticofugal neurons from striatal progenitors in vivo. Nature Neuroscience. 13: 1345-7. PMID 20953195 DOI: 10.1038/Nn.2658  0.846
2010 Tomassy GS, Lodato S, Trayes-Gibson Z, Arlotta P. Development and regeneration of projection neuron subtypes of the cerebral cortex. Science Progress. 93: 151-69. PMID 20681320 DOI: 10.3184/003685010X12705764469952  0.848
2010 Shoemaker LD, Arlotta P. Untangling the cortex: Advances in understanding specification and differentiation of corticospinal motor neurons. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 32: 197-206. PMID 20108227 DOI: 10.1002/Bies.200900114  0.652
2010 Lodato S, Tomassy GS, De Leonibus E, Arlotta P, Prida LM, Studer M. [P2.20]: Loss of coup‐tfi results in increased generation of PV‐expressing interneurons and resistance to epileptic seizures International Journal of Developmental Neuroscience. 28: 693-693. DOI: 10.1016/J.Ijdevneu.2010.07.150  0.698
2010 Lodato S, Meleski A, Molyneaux B, Arlotta P. [P1.44]: Molecular signals governing early development of corticospinal motor neurons by Fezf2 International Journal of Developmental Neuroscience. 28: 670-670. DOI: 10.1016/J.Ijdevneu.2010.07.085  0.816
2010 Rouaux C, Arlotta P. [P1.43]: Fate‐switch of basal ganglia progenitors and reprogramming of young cortical neurons into corticospinal motor neurons International Journal of Developmental Neuroscience. 28: 670-670. DOI: 10.1016/J.Ijdevneu.2010.07.084  0.823
2009 Molyneaux BJ, Arlotta P, Fame RM, MacDonald JL, MacQuarrie KL, Macklis JD. Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12343-54. PMID 19793993 DOI: 10.1523/JNEUROSCI.6108-08.2009  0.826
2008 Lai T, Jabaudon D, Molyneaux BJ, Azim E, Arlotta P, Menezes JR, Macklis JD. SOX5 controls the sequential generation of distinct corticofugal neuron subtypes. Neuron. 57: 232-47. PMID 18215621 DOI: 10.1016/j.neuron.2007.12.023  0.857
2008 Arlotta P, Molyneaux BJ, Jabaudon D, Yoshida Y, Macklis JD. Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 622-32. PMID 18199763 DOI: 10.1523/JNEUROSCI.2986-07.2008  0.815
2008 Lai T, Jabaudon D, Molyneaux BJ, Azim E, Arlotta P, Menezes JRL, Macklis JD. SOX5 Controls the Sequential Generation of Distinct Corticofugal Neuron Subtypes (DOI:10.1016/j.neuron.2007.12.023) Neuron. 57: 626. DOI: 10.1016/j.neuron.2008.02.001  0.846
2007 Molyneaux BJ, Arlotta P, Macklis JD. Molecular development of corticospinal motor neuron circuitry. Novartis Foundation Symposium. 288: 3-15; discussion 15-. PMID 18494249 DOI: 10.1016/j.expneurol.2006.02.074  0.869
2007 Gao X, Arlotta P, Macklis JD, Chen J. Conditional knock-out of beta-catenin in postnatal-born dentate gyrus granule neurons results in dendritic malformation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14317-25. PMID 18160639 DOI: 10.1523/JNEUROSCI.3206-07.2007  0.857
2007 Molyneaux BJ, Arlotta P, Menezes JR, Macklis JD. Neuronal subtype specification in the cerebral cortex. Nature Reviews. Neuroscience. 8: 427-37. PMID 17514196 DOI: 10.1038/nrn2151  0.872
2006 ARLOTTA P, MAGAVI SS, MACKLIS JD. Induction of Adult Neurogenesis Annals of the New York Academy of Sciences. 991: 229-236. DOI: 10.1111/J.1749-6632.2003.TB07479.X  0.859
2005 Molyneaux BJ, Arlotta P, Hirata T, Hibi M, Macklis JD. Fezl is required for the birth and specification of corticospinal motor neurons. Neuron. 47: 817-31. PMID 16157277 DOI: 10.1016/j.neuron.2005.08.030  0.872
2005 Arlotta P, Macklis JD. Archeo-cell biology: carbon dating is not just for pots and dinosaurs. Cell. 122: 4-6. PMID 16009125 DOI: 10.1016/j.cell.2005.06.037  0.691
2005 Arlotta P, Molyneaux BJ, Chen J, Inoue J, Kominami R, Macklis JD. Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo. Neuron. 45: 207-21. PMID 15664173 DOI: 10.1016/j.neuron.2004.12.036  0.864
2004 Emsley JG, Mitchell BD, Magavi SS, Arlotta P, Macklis JD. The repair of complex neuronal circuitry by transplanted and endogenous precursors. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 1: 452-71. PMID 15717047 DOI: 10.1602/neurorx.1.4.452  0.85
2004 Mitchell BD, Emsley JG, Magavi SS, Arlotta P, Macklis JD. Constitutive and induced neurogenesis in the adult mammalian brain: manipulation of endogenous precursors toward CNS repair. Developmental Neuroscience. 26: 101-17. PMID 15711054 DOI: 10.1159/000082131  0.847
2004 Catapano LA, Arlotta P, Cage TA, Macklis JD. Stage-specific and opposing roles of BDNF, NT-3 and bFGF in differentiation of purified callosal projection neurons toward cellular repair of complex circuitry. The European Journal of Neuroscience. 19: 2421-34. PMID 15128396 DOI: 10.1111/j.0953-816X.2004.03303.x  0.871
2004 Emsley JG, Arlotta P, Macklis JD. Star-cross'd neurons: astroglial effects on neural repair in the adult mammalian CNS. Trends in Neurosciences. 27: 238-40. PMID 15111002 DOI: 10.1016/j.tins.2004.02.008  0.854
2003 Arlotta P, Magavi SS, Macklis JD. Induction of adult neurogenesis: molecular manipulation of neural precursors in situ. Annals of the New York Academy of Sciences. 991: 229-36. PMID 12846990 DOI: 10.1007/978-1-59259-298-2_9  0.858
2003 Arlotta P, Magavi SS, Macklis JD. Molecular manipulation of neural precursors in situ: induction of adult cortical neurogenesis. Experimental Gerontology. 38: 173-82. PMID 12543275 DOI: 10.1016/S0531-5565(02)00156-0  0.868
2002 Arlotta P, Miyazaki D, Copeland NG, Gilbert DJ, Jenkins NA, Ono SJ. Murine NFX.1: isolation and characterization of its messenger RNA, mapping of its chromosomal location and assessment of its developmental expression. Immunology. 106: 173-81. PMID 12047746 DOI: 10.1046/J.1365-2567.2002.01416.X  0.318
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