Stephan J. Guyenet, Ph.D. - Publications

Affiliations: 
2009 University of Washington, Seattle, Seattle, WA 
Area:
Neuroscience Biology

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Meek TH, Nelson JT, Matsen ME, Dorfman MD, Guyenet SJ, Damian V, Allison MB, Scarlett JM, Nguyen HT, Thaler JP, Olson DP, Myers MG, Schwartz MW, Morton GJ. Functional identification of a neurocircuit regulating blood glucose. Proceedings of the National Academy of Sciences of the United States of America. PMID 27001850 DOI: 10.1073/pnas.1521160113  0.52
2015 Schur EA, Melhorn SJ, Oh SK, Lacy JM, Berkseth KE, Guyenet SJ, Sonnen JA, Tyagi V, Rosalynn M, De Leon B, Webb MF, Gonsalves ZT, Fligner CL, Schwartz MW, Maravilla KR. Radiologic evidence that hypothalamic gliosis is associated with obesity and insulin resistance in humans. Obesity (Silver Spring, Md.). 23: 2142-8. PMID 26530930 DOI: 10.1002/oby.21248  0.52
2015 Guyenet SJ, Mookerjee SS, Lin A, Custer SK, Chen SF, Sopher BL, La Spada AR, Ellerby LM. Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction. Human Molecular Genetics. 24: 3908-17. PMID 25859008 DOI: 10.1093/hmg/ddv121  0.52
2014 McCormick MA, Mason AG, Guyenet SJ, Dang W, Garza RM, Ting MK, Moller RM, Berger SL, Kaeberlein M, Pillus L, La Spada AR, Kennedy BK. The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction. Cell Reports. 8: 477-86. PMID 25043177 DOI: 10.1016/j.celrep.2014.06.037  0.52
2014 Berkseth KE, Guyenet SJ, Melhorn SJ, Lee D, Thaler JP, Schur EA, Schwartz MW. Hypothalamic gliosis associated with high-fat diet feeding is reversible in mice: a combined immunohistochemical and magnetic resonance imaging study. Endocrinology. 155: 2858-67. PMID 24914942 DOI: 10.1210/en.2014-1121  0.52
2013 Guyenet SJ, Matsen ME, Morton GJ, Kaiyala KJ, Schwartz MW. Rapid glutamate release in the mediobasal hypothalamus accompanies feeding and is exaggerated by an obesogenic food. Molecular Metabolism. 2: 116-22. PMID 24199157 DOI: 10.1016/j.molmet.2013.02.001  0.52
2013 Thaler JP, Guyenet SJ, Dorfman MD, Wisse BE, Schwartz MW. Hypothalamic inflammation: marker or mechanism of obesity pathogenesis? Diabetes. 62: 2629-34. PMID 23881189 DOI: 10.2337/db12-1605  0.52
2013 Meek TH, Matsen ME, Dorfman MD, Guyenet SJ, Damian V, Nguyen HT, Taborsky GJ, Morton GJ. Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia. Endocrinology. 154: 3067-76. PMID 23782941 DOI: 10.1210/en.2013-1328  0.52
2013 Guyenet SJ, Nguyen HT, Hwang BH, Schwartz MW, Baskin DG, Thaler JP. High-fat diet feeding causes rapid, non-apoptotic cleavage of caspase-3 in astrocytes. Brain Research. 1512: 97-105. PMID 23548599 DOI: 10.1016/j.brainres.2013.03.033  0.52
2013 Matsen ME, Thaler JP, Wisse BE, Guyenet SJ, Meek TH, Ogimoto K, Cubelo A, Fischer JD, Kaiyala KJ, Schwartz MW, Morton GJ. In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue. American Journal of Physiology. Endocrinology and Metabolism. 304: E734-46. PMID 23384771 DOI: 10.1152/ajpendo.00488.2012  0.52
2013 Meek TH, Wisse BE, Thaler JP, Guyenet SJ, Matsen ME, Fischer JD, Taborsky GJ, Schwartz MW, Morton GJ. BDNF action in the brain attenuates diabetic hyperglycemia via insulin-independent inhibition of hepatic glucose production. Diabetes. 62: 1512-8. PMID 23274899 DOI: 10.2337/db12-0837  0.52
2012 Guyenet SJ, Schwartz MW. Clinical review: Regulation of food intake, energy balance, and body fat mass: implications for the pathogenesis and treatment of obesity. The Journal of Clinical Endocrinology and Metabolism. 97: 745-55. PMID 22238401 DOI: 10.1210/jc.2011-2525  0.52
2012 Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, et al. Obesity is associated with hypothalamic injury in rodents and humans. The Journal of Clinical Investigation. 122: 153-62. PMID 22201683 DOI: 10.1172/JCI59660  0.52
2012 Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, et al. Obesity is associated with hypothalamic injury in rodents and humans (The Journal of Clinical Investigation (2012) 122, 1, (153-162) DOI: 10.1172/JCI59660) Journal of Clinical Investigation. 122: 778. DOI: 10.1172/JCI62813  0.52
2010 Schwartz MW, Guyenet SJ, Cirulli V. The hypothalamus and ß-cell connection in the gene-targeting era. Diabetes. 59: 2991-3. PMID 21115781 DOI: 10.2337/db10-1149  0.52
2010 Guyenet SJ, Furrer SA, Damian VM, Baughan TD, La Spada AR, Garden GA. A simple composite phenotype scoring system for evaluating mouse models of cerebellar ataxia. Journal of Visualized Experiments : Jove. PMID 20495529 DOI: 10.3791/1787  0.52
2009 Mookerjee S, Papanikolaou T, Guyenet SJ, Sampath V, Lin A, Vitelli C, DeGiacomo F, Sopher BL, Chen SF, La Spada AR, Ellerby LM. Posttranslational modification of ataxin-7 at lysine 257 prevents autophagy-mediated turnover of an N-terminal caspase-7 cleavage fragment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15134-44. PMID 19955365 DOI: 10.1523/JNEUROSCI.4720-09.2009  0.52
2007 Baraban SC, Dinday MT, Castro PA, Chege S, Guyenet S, Taylor MR. A large-scale mutagenesis screen to identify seizure-resistant zebrafish. Epilepsia. 48: 1151-7. PMID 17521353 DOI: 10.1111/j.1528-1167.2007.01075.x  0.52
2006 Custer SK, Garden GA, Gill N, Rueb U, Libby RT, Schultz C, Guyenet SJ, Deller T, Westrum LE, Sopher BL, La Spada AR. Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport. Nature Neuroscience. 9: 1302-11. PMID 16936724 DOI: 10.1038/nn1750  0.52
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