| Year |
Citation |
Score |
| 2023 |
Fernandez-Valle C, Nagel A, Huegel J, Petrilli A, Rosario R, Victoria B, Hardin H. Simultaneous Inhibition of PI3K and PAK in Preclinical Models of Neurofibromatosis Type 2-related Schwannomatosis. Research Square. PMID 37886501 DOI: 10.21203/rs.3.rs-3405297/v1 |
0.376 |
|
| 2023 |
Hardin HM, Dinh CT, Huegel J, Petrilli AM, Bracho O, Allaf A, Karajannis MA, Griswold AJ, Ivan ME, Morcos J, Gultekin SH, Telischi FF, Liu XZ, Fernandez-Valle C. Co-targeting Phosphoinositide 3-Kinase and Focal Adhesion Kinase Pathways Inhibits Proliferation of NF2 Schwannoma Cells. Molecular Cancer Therapeutics. PMID 37527526 DOI: 10.1158/1535-7163.MCT-23-0135 |
0.386 |
|
| 2022 |
Huegel J, Dinh CT, Martinelli M, Bracho O, Rosario R, Hardin H, Estivill M, Griswold A, Gultekin S, Liu XZ, Fernandez-Valle C. CUDC907, a dual phosphoinositide-3 kinase/histone deacetylase inhibitor, promotes apoptosis of NF2 Schwannoma cells. Oncotarget. 13: 890-904. PMID 35875610 DOI: 10.18632/oncotarget.28254 |
0.388 |
|
| 2021 |
Chang LS, Oblinger JL, Smith AE, Ferrer M, Angus SP, Hawley E, Petrilli AM, Beauchamp RL, Riecken LB, Erdin S, Poi M, Huang J, Bessler WK, Zhang X, Guha R, ... ... Fernandez-Valle C, et al. Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK. Plos One. 16: e0252048. PMID 34264955 DOI: 10.1371/journal.pone.0252048 |
0.401 |
|
| 2019 |
Ein L, Bracho O, Mei C, Patel J, Boyle T, Monje P, Fernandez-Valle C, Bas E, Thomas G, Weed D, Sargi Z, Dinh C. Inhibition of tropomyosine receptor kinase B on the migration of human Schwann cell and dispersion of oral tongue squamous cell carcinoma in vitro. Head & Neck. PMID 31497919 DOI: 10.1002/Hed.25956 |
0.415 |
|
| 2019 |
Pestoni JC, Klingeman Plati S, Valdivia Camacho OD, Fuse MA, Onatunde M, Sparrow NA, Karajannis MA, Fernández-Valle C, Franco MC. Peroxynitrite supports a metabolic reprogramming in merlin-deficient Schwann cells and promotes cell survival. The Journal of Biological Chemistry. PMID 31171721 DOI: 10.1074/Jbc.Ra118.007152 |
0.465 |
|
| 2019 |
Fuse MA, Dinh CT, Vitte J, Kirkpatrick J, Mindos T, Plati SK, Young JI, Huang J, Carlstedt A, Franco MC, Brnjos K, Nagamoto J, Petrilli A, Copik AJ, Soulakova JN, ... ... Fernandez-Valle C, et al. Preclinical Assessment of MEK1/2 Inhibitors for Neurofibromatosis Type 2-Associated Schwannomas Reveal Differences in Efficacy and Drug Resistance Development. Neuro-Oncology. PMID 30615146 DOI: 10.1093/Neuonc/Noz002 |
0.413 |
|
| 2018 |
Perez ER, Bracho O, Ein L, Szczupak M, Monje PV, Fernandez-Valle C, Alshaiji A, Ivan M, Morcos J, Liu XZ, Hoffer M, Eshraghi A, Angeli S, Telischi F, Dinh CT. Fluorescent Detection of Merlin-deficient Schwann Cells and Primary Human Vestibular Schwannoma Cells Using Sodium Fluorescein. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. PMID 30001282 DOI: 10.1097/Mao.0000000000001895 |
0.368 |
|
| 2018 |
Allaway R, Angus SP, Beauchamp RL, Blakeley JO, Bott M, Burns SS, Carlstedt A, Chang LS, Chen X, Clapp DW, Desouza PA, Erdin S, Fernandez-Valle C, Guinney J, et al. Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2. Plos One. 13: e0197350. PMID 29897904 DOI: 10.1371/Journal.Pone.0197350 |
0.404 |
|
| 2018 |
Dinh CT, Bracho O, Mei C, Bas E, Fernandez-Valle C, Telischi F, Liu XZ. A Xenograft Model of Vestibular Schwannoma and Hearing Loss. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. PMID 29557843 DOI: 10.1097/Mao.0000000000001766 |
0.328 |
|
| 2018 |
Petrilli AM, Fernández-Valle C. Generation and Use of Merlin-Deficient Human Schwann Cells for a High-Throughput Chemical Genomics Screening Assay. Methods in Molecular Biology (Clifton, N.J.). 1739: 161-173. PMID 29546707 DOI: 10.1007/978-1-4939-7649-2_11 |
0.415 |
|
| 2018 |
Camacho OV, Pestoni J, Fernandez-Valle C, Franco MC. Tyrosine nitration regulates signaling pathways involved in Neurofibromatosis type 2-associated Schwannoma growth Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.223 |
0.504 |
|
| 2018 |
Pestoni J, Camacho OV, Riordan R, Kim S, Fernandez-Valle C, Franco MC. Tyrosine nitration induces a metabolic reprogramming in neurofibromatosis type 2-associated Schwannoma cells Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.212 |
0.489 |
|
| 2017 |
Fuse MA, Klingeman Plati S, Burns SS, Dinh CT, Bracho O, Yan D, Mittal R, Shen R, Soulakova JN, Copik AJ, Liu XZ, Telischi FF, Chang LS, Franco MC, Fernandez-Valle C. Combination Therapy With c-Met and Src Inhibitors Induces Caspase-Dependent Apoptosis of Merlin-Deficient Schwann Cells and Suppresses Growth of Schwannoma Cells. Molecular Cancer Therapeutics. PMID 28775147 DOI: 10.1158/1535-7163.Mct-17-0417 |
0.464 |
|
| 2017 |
Petrilli AM, Garcia J, Bott M, Klingeman Plati S, Dinh CT, Bracho OR, Yan D, Zou B, Mittal R, Telischi FF, Liu XZ, Chang LS, Welling DB, Copik AJ, Fernández-Valle C. Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cells. Oncotarget. PMID 28427224 DOI: 10.18632/Oncotarget.15912 |
0.538 |
|
| 2017 |
Franco MC, Plati SK, Onatunde MO, Sparrow NA, Fuse MA, Fernandez-Valle C. Tyrosine Nitration is Necessary for the Survival of Schwannoma Cells Free Radical Biology and Medicine. 112: 86-87. DOI: 10.1016/J.Freeradbiomed.2017.10.125 |
0.453 |
|
| 2015 |
Petrilli AM, Fernández-Valle C. Role of Merlin/NF2 inactivation in tumor biology. Oncogene. PMID 25893302 DOI: 10.1038/Onc.2015.125 |
0.433 |
|
| 2014 |
Petrilli AM, Fuse MA, Donnan MS, Bott M, Sparrow NA, Tondera D, Huffziger J, Frenzel C, Malany CS, Echeverri CJ, Smith L, Fernández-Valle C. A chemical biology approach identified PI3K as a potential therapeutic target for neurofibromatosis type 2. American Journal of Translational Research. 6: 471-93. PMID 25360213 |
0.325 |
|
| 2014 |
Lee MW, Bassiouni R, Sparrow NA, Iketani A, Boohaker RJ, Moskowitz C, Vishnubhotla P, Khaled AS, Oyer J, Copik A, Fernandez-Valle C, Perez JM, Khaled AR. The CT20 peptide causes detachment and death of metastatic breast cancer cells by promoting mitochondrial aggregation and cytoskeletal disruption. Cell Death & Disease. 5: e1249. PMID 24853427 DOI: 10.1038/Cddis.2014.225 |
0.322 |
|
| 2014 |
Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovannini M, et al. CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies. American Journal of Medical Genetics. Part A. 164: 563-78. PMID 24443315 DOI: 10.1002/Ajmg.A.36312 |
0.392 |
|
| 2014 |
Petrilli A, Copik A, Posadas M, Chang LS, Welling DB, Giovannini M, Fernández-Valle C. LIM domain kinases as potential therapeutic targets for neurofibromatosis type 2. Oncogene. 33: 3571-82. PMID 23934191 DOI: 10.1038/onc.2013.320 |
0.462 |
|
| 2013 |
Petrilli A, Bott M, Fernández-Valle C. Inhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis. Oncotarget. 4: 2354-65. PMID 24259290 DOI: 10.18632/Oncotarget.1422 |
0.447 |
|
| 2013 |
Douglass KM, Sparrow NA, Bott M, Fernandez-Valle C, Dogariu A. Measuring anisotropic cell motility on curved substrates. Journal of Biophotonics. 6: 387-92. PMID 22887747 DOI: 10.1002/Jbio.201200089 |
0.303 |
|
| 2012 |
Manetti ME, Geden S, Bott M, Sparrow N, Lambert S, Fernandez-Valle C. Stability of the tumor suppressor merlin depends on its ability to bind paxillin LD3 and associate with β1 integrin and actin at the plasma membrane. Biology Open. 1: 949-57. PMID 23213372 DOI: 10.1242/Bio.20122121 |
0.438 |
|
| 2012 |
Sparrow N, Manetti ME, Bott M, Fabianac T, Petrilli A, Bates ML, Bunge MB, Lambert S, Fernandez-Valle C. The actin-severing protein cofilin is downstream of neuregulin signaling and is essential for Schwann cell myelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5284-97. PMID 22496574 DOI: 10.1523/Jneurosci.6207-11.2012 |
0.478 |
|
| 2011 |
Thaxton C, Bott M, Walker B, Sparrow NA, Lambert S, Fernandez-Valle C. Schwannomin/merlin promotes Schwann cell elongation and influences myelin segment length. Molecular and Cellular Neurosciences. 47: 1-9. PMID 21182951 DOI: 10.1016/J.Mcn.2010.12.006 |
0.636 |
|
| 2009 |
Rumsey JW, Das M, Stancescu M, Bott M, Fernandez-Valle C, Hickman JJ. Node of Ranvier formation on motoneurons in vitro. Biomaterials. 30: 3567-72. PMID 19361859 DOI: 10.1016/J.Biomaterials.2009.03.023 |
0.374 |
|
| 2008 |
Thaxton C, Lopera J, Bott M, Fernandez-Valle C. Neuregulin and laminin stimulate phosphorylation of the NF2 tumor suppressor in Schwann cells by distinct protein kinase A and p21-activated kinase-dependent pathways. Oncogene. 27: 2705-15. PMID 17998937 DOI: 10.1038/Sj.Onc.1210923 |
0.666 |
|
| 2007 |
Iacovelli J, Lopera J, Bott M, Baldwin E, Khaled A, Uddin N, Fernandez-Valle C. Serum and forskolin cooperate to promote G1 progression in Schwann cells by differentially regulating cyclin D1, cyclin E1, and p27Kip expression. Glia. 55: 1638-47. PMID 17849471 DOI: 10.1002/Glia.20578 |
0.423 |
|
| 2007 |
Thaxton C, Lopera J, Bott M, Baldwin ME, Kalidas P, Fernandez-Valle C. Phosphorylation of the NF2 tumor suppressor in Schwann cells is mediated by Cdc42-Pak and requires paxillin binding. Molecular and Cellular Neurosciences. 34: 231-42. PMID 17175165 DOI: 10.1016/J.Mcn.2006.11.003 |
0.67 |
|
| 2003 |
Taylor AR, Geden SE, Fernandez-Valle C. Formation of a beta1 integrin signaling complex in Schwann cells is independent of rho. Glia. 41: 94-104. PMID 12465049 DOI: 10.1002/Glia.10170 |
0.32 |
|
| 2002 |
Fernandez-Valle C, Tang Y, Ricard J, Rodenas-Ruano A, Taylor A, Hackler E, Biggerstaff J, Iacovelli J. Paxillin binds schwannomin and regulates its density-dependent localization and effect on cell morphology. Nature Genetics. 31: 354-62. PMID 12118253 DOI: 10.1038/Ng930 |
0.399 |
|
| 2000 |
Chen LM, Bailey D, Fernandez-Valle C. Association of beta 1 integrin with focal adhesion kinase and paxillin in differentiating Schwann cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3776-84. PMID 10804218 |
0.398 |
|
| 2000 |
Chen L, Bailey D, Fernandez-Valle C. Association of β1 Integrin with Focal Adhesion Kinase and Paxillin in Differentiating Schwann Cells The Journal of Neuroscience. 20: 3776-3784. DOI: 10.1523/Jneurosci.20-10-03776.2000 |
0.464 |
|
| 1998 |
Obremski VJ, Hall AM, Fernandez-Valle C. Merlin, the neurofibromatosis type 2 gene product, and beta1 integrin associate in isolated and differentiating Schwann cells. Journal of Neurobiology. 37: 487-501. PMID 9858254 DOI: 10.1002/(Sici)1097-4695(199812)37:4<487::Aid-Neu1>3.0.Co;2-B |
0.418 |
|
| 1998 |
Fernandez-Valle C, Wood PM, Bunge MB. Localization of focal adhesion kinase in differentiating Schwann cell/neuron cultures. Microscopy Research and Technique. 41: 416-30. PMID 9672424 DOI: 10.1002/(Sici)1097-0029(19980601)41:5<416::Aid-Jemt8>3.0.Co;2-N |
0.462 |
|
| 1997 |
Fernandez-Valle C, Gorman D, Gomez AM, Bunge MB. Actin plays a role in both changes in cell shape and gene-expression associated with Schwann cell myelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 241-50. PMID 8987752 DOI: 10.1523/Jneurosci.17-01-00241.1997 |
0.317 |
|
| Show low-probability matches. |