Year |
Citation |
Score |
2023 |
Gunner CB, Azmoon P, Mantuano E, Das L, Zampieri C, Pizzo SV, Gonias SL. An antibody that targets cell-surface glucose-regulated protein-78 inhibits expression of inflammatory cytokines and plasminogen activator inhibitors by macrophages. Journal of Cellular Biochemistry. PMID 36947703 DOI: 10.1002/jcb.30401 |
0.32 |
|
2022 |
Mantuano E, Azmoon P, Banki MA, Gunner CB, Gonias SL. The LRP1/CD91 ligands, tissue-type plasminogen activator, α-macroglobulin, and soluble cellular prion protein have distinct co-receptor requirements for activation of cell-signaling. Scientific Reports. 12: 17594. PMID 36266319 DOI: 10.1038/s41598-022-22498-1 |
0.317 |
|
2021 |
Sadri M, Hirosawa N, Le J, Romero H, Martellucci S, Kwon HJ, Pizzo D, Ohtori S, Gonias SL, Campana WM. Tumor necrosis factor receptor-1 is selectively sequestered into Schwann cell extracellular vesicles where it functions as a TNFα decoy. Glia. PMID 34559433 DOI: 10.1002/glia.24098 |
0.317 |
|
2021 |
Gonias SL. Plasminogen activator receptor assemblies in cell-signaling, innate immunity, and inflammation. American Journal of Physiology. Cell Physiology. PMID 34406905 DOI: 10.1152/ajpcell.00269.2021 |
0.314 |
|
2020 |
Mantuano E, Azmoon P, Banki MA, Lam MS, Sigurdson CJ, Gonias SL. A soluble derivative of PrP activates cell-signaling and regulates cell physiology through LRP1 and the NMDA Receptor. The Journal of Biological Chemistry. PMID 32788217 DOI: 10.1074/Jbc.Ra120.013779 |
0.444 |
|
2019 |
Shiga Y, Shiga A, Mesci P, Kwon H, Brifault C, Kim JH, Jeziorski JJ, Nasamran C, Ohtori S, Muotri AR, Gonias SL, Campana WM. Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury. Scientific Reports. 9: 19291. PMID 31848365 DOI: 10.1038/S41598-019-55132-8 |
0.32 |
|
2019 |
Pontecorvi P, Banki MA, Zampieri C, Zalfa C, Azmoon P, Kounnas MZ, Marchese C, Gonias SL, Mantuano E. Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines. Journal of Neuroinflammation. 16: 257. PMID 31810478 DOI: 10.1186/S12974-019-1657-3 |
0.318 |
|
2019 |
Gonias SL, Zampieri C. Plasminogen Receptors in Human Malignancies: Effects on Prognosis and Feasibility as Targets for Drug Development. Current Drug Targets. PMID 31755385 DOI: 10.2174/1389450120666191122101658 |
0.458 |
|
2019 |
Das L, Azmoon P, Banki MA, Mantuano E, Gonias SL. Tissue-type plasminogen activator selectively inhibits multiple toll-like receptors in CSF-1-differentiated macrophages. Plos One. 14: e0224738. PMID 31697716 DOI: 10.1371/Journal.Pone.0224738 |
0.376 |
|
2019 |
Brifault C, Kwon H, Campana WM, Gonias SL. LRP1 deficiency in microglia blocks neuro-inflammation in the spinal dorsal horn and neuropathic pain processing. Glia. PMID 30746765 DOI: 10.1002/Glia.23599 |
0.323 |
|
2019 |
Zalfa C, Azmoon P, Mantuano E, Gonias SL. Tissue-type plasminogen activator neutralizes LPS but not protease-activated receptor-mediated inflammatory responses to plasmin. Journal of Leukocyte Biology. PMID 30690783 DOI: 10.1002/Jlb.3A0818-329Rrr |
0.358 |
|
2018 |
Gonias SL, Banki MA, Gilder AS, Azmoon P, Campana WM, Mantuano E. PAI1 blocks effects of tissue-type plasminogen activator on cell-signaling and physiology mediated by the NMDA receptor. Journal of Cell Science. PMID 29930084 DOI: 10.1242/Jcs.217083 |
0.48 |
|
2018 |
Gilder AS, Natali L, Van Dyk DM, Zalfa C, Banki MA, Pizzo DP, Wang H, Klemke RL, Mantuano E, Gonias SL. The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres. Scientific Reports. 8: 2982. PMID 29445239 DOI: 10.1038/S41598-018-21358-1 |
0.443 |
|
2017 |
Gonias SL, Karimi-Mostowfi N, Murray SS, Mantuano E, Gilder AS. Expression of LDL receptor-related proteins (LRPs) in common solid malignancies correlates with patient survival. Plos One. 12: e0186649. PMID 29088295 DOI: 10.1371/Journal.Pone.0186649 |
0.348 |
|
2017 |
Brifault C, Gilder AS, Laudati E, Banki M, Gonias SL. Shedding of membrane-associated LDL receptor-related protein-1 from microglia amplifies and sustains neuro-inflammation. The Journal of Biological Chemistry. PMID 28972143 DOI: 10.1074/Jbc.M117.798413 |
0.399 |
|
2017 |
Mantuano E, Azmoon P, Brifault C, Banki MA, Gilder AS, Campana WM, Gonias SL. Tissue-type Plasminogen Activator Regulates Macrophage Activation and Innate Immunity. Blood. PMID 28684538 DOI: 10.1182/Blood-2017-04-780205 |
0.399 |
|
2017 |
Campana WM, Mantuano E, Azmoon P, Henry K, Banki MA, Kim JH, Pizzo DP, Gonias SL. Ionotropic glutamate receptors activate cell signaling in response to glutamate in Schwann cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28073836 DOI: 10.1096/Fj.201601121R |
0.376 |
|
2016 |
Gilder AS, Wang L, Natali L, Karimi-Mostowfi N, Brifault C, Gonias SL. Pertussis Toxin Is a Robust and Selective Inhibitor of High Grade Glioma Cell Migration and Invasion. Plos One. 11: e0168418. PMID 27977780 DOI: 10.1371/Journal.Pone.0168418 |
0.448 |
|
2016 |
Flütsch A, Henry K, Mantuano E, Lam MS, Shibayama M, Takahashi K, Gonias SL, Campana WM. Evidence that LDL receptor-related protein 1 acts as an early injury detection receptor and activates c-Jun in Schwann cells. Neuroreport. 27: 1305-1311. PMID 27824728 DOI: 10.1097/Wnr.0000000000000691 |
0.417 |
|
2016 |
Hau AM, Leivo MZ, Gilder AS, Hu JJ, Gonias SL, Hansel DE. mTORC2 activation is regulated by the urokinase receptor (uPAR) in bladder cancer. Cellular Signalling. PMID 27777073 DOI: 10.1016/J.Cellsig.2016.10.010 |
0.429 |
|
2016 |
Laudati E, Gilder AS, Lam MS, Misasi R, Sorice M, Gonias SL, Mantuano E. The activities of LDL receptor-related protein-1 (LRP1) compartmentalize into distinct plasma membrane microdomains. Molecular and Cellular Neurosciences. PMID 27565578 DOI: 10.1016/J.Mcn.2016.08.006 |
0.4 |
|
2016 |
Mantuano E, Brifault C, Lam MS, Azmoon P, Gilder AS, Gonias SL. LDL receptor-related protein-1 regulates NFκB and microRNA-155 in macrophages to control the inflammatory response. Proceedings of the National Academy of Sciences of the United States of America. 113: 1369-74. PMID 26787872 DOI: 10.1073/Pnas.1515480113 |
0.378 |
|
2016 |
Hau AM, Gilder A, Hu J, Gonias SL, Hansel DE. uPAR and mTORC2 as coupled targets for therapeutics development in bladder cancer. Journal of Clinical Oncology. 34: 447-447. DOI: 10.1200/Jco.2016.34.2_Suppl.447 |
0.376 |
|
2015 |
Jones KA, Gilder AS, Lam MS, Du N, Banki MA, Merati A, Pizzo DP, VandenBerg SR, Gonias SL. Selective coexpression of VEGF receptor 2 in EGFRvIII-positive glioblastoma cells prevents cellular senescence and contributes to their aggressive nature. Neuro-Oncology. PMID 26420897 DOI: 10.1093/Neuonc/Nov243 |
0.773 |
|
2015 |
Gonias SL, Hu J. Urokinase receptor and resistance to targeted anticancer agents. Frontiers in Pharmacology. 6: 154. PMID 26283964 DOI: 10.3389/Fphar.2015.00154 |
0.482 |
|
2015 |
Mantuano E, Lam MS, Shibayama M, Campana WM, Gonias SL. The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration. Journal of Cell Science. 128: 3478-88. PMID 26272917 DOI: 10.1242/Jcs.173765 |
0.416 |
|
2015 |
Gilder AS, Jones KA, Hu J, Wang L, Chen CC, Carter BS, Gonias SL. Soluble Urokinase Receptor Is Released Selectively by Glioblastoma Cells That Express Epidermal Growth Factor Receptor Variant III and Promotes Tumor Cell Migration and Invasion. The Journal of Biological Chemistry. 290: 14798-809. PMID 25837250 DOI: 10.1074/Jbc.M115.637488 |
0.779 |
|
2015 |
Wykosky J, Hu J, Gomez GG, Taylor T, Villa GR, Pizzo D, VandenBerg SR, Thorne AH, Chen CC, Mischel PS, Gonias SL, Cavenee WK, Furnari FB. A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma. Cancer Research. 75: 394-404. PMID 25432173 DOI: 10.1158/0008-5472.Can-14-2004 |
0.568 |
|
2015 |
Pasillas MP, Shields S, Reilly R, Strnadel J, Behl C, Park R, Yates JR, Klemke R, Gonias SL, Coppinger JA. Proteomic analysis reveals a role for Bcl2-associated athanogene 3 and major vault protein in resistance to apoptosis in senescent cells by regulating ERK1/2 activation. Molecular & Cellular Proteomics : McP. 14: 1-14. PMID 24997994 DOI: 10.1074/Mcp.M114.037697 |
0.404 |
|
2014 |
Hu J, Muller KA, Furnari FB, Cavenee WK, VandenBerg SR, Gonias SL. Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling. Oncogene. PMID 25347738 DOI: 10.1038/onc.2014.336 |
0.64 |
|
2014 |
Hu J, Jo M, Eastman BM, Gilder AS, Bui JD, Gonias SL. uPAR induces expression of transforming growth factor β and interleukin-4 in cancer cells to promote tumor-permissive conditioning of macrophages. The American Journal of Pathology. 184: 3384-93. PMID 25310970 DOI: 10.1016/J.Ajpath.2014.08.003 |
0.791 |
|
2014 |
Gonias SL, Campana WM. LDL receptor-related protein-1: a regulator of inflammation in atherosclerosis, cancer, and injury to the nervous system. The American Journal of Pathology. 184: 18-27. PMID 24128688 DOI: 10.1016/J.Ajpath.2013.08.029 |
0.441 |
|
2014 |
Pasillas M, Shields S, Reilly R, Mulrane L, Strnadnel J, Jirstrom K, Connor DO, Gallagher W, Gonias S, Coppinger J. Abstract LB-18: Bcl2-associated athanogene 3 and major vault protein regulate cell survival and resistance to apoptosis in senescent cells by regulating ERK activation Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-18 |
0.433 |
|
2013 |
Gupta S, Hau AM, Beach JR, Harwalker J, Mantuano E, Gonias SL, Egelhoff TT, Hansel DE. Mammalian target of rapamycin complex 2 (mTORC2) is a critical determinant of bladder cancer invasion. Plos One. 8: e81081. PMID 24312263 DOI: 10.1371/Journal.Pone.0081081 |
0.359 |
|
2013 |
Mantuano E, Lam MS, Gonias SL. LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein. The Journal of Biological Chemistry. 288: 34009-18. PMID 24129569 DOI: 10.1074/Jbc.M113.509133 |
0.464 |
|
2013 |
Staudt ND, Jo M, Hu J, Bristow JM, Pizzo DP, Gaultier A, VandenBerg SR, Gonias SL. Myeloid cell receptor LRP1/CD91 regulates monocyte recruitment and angiogenesis in tumors. Cancer Research. 73: 3902-12. PMID 23633492 DOI: 10.1158/0008-5472.Can-12-4233 |
0.629 |
|
2013 |
Orita S, Henry K, Mantuano E, Yamauchi K, De Corato A, Ishikawa T, Feltri ML, Wrabetz L, Gaultier A, Pollack M, Ellisman M, Takahashi K, Gonias SL, Campana WM. Schwann cell LRP1 regulates remak bundle ultrastructure and axonal interactions to prevent neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5590-602. PMID 23536074 DOI: 10.1523/Jneurosci.3342-12.2013 |
0.301 |
|
2013 |
Fernandez-Castaneda A, Arandjelovic S, Stiles TL, Schlobach RK, Mowen KA, Gonias SL, Gaultier A. Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris. The Journal of Biological Chemistry. 288: 4538-48. PMID 23264627 DOI: 10.1074/Jbc.M112.384693 |
0.361 |
|
2013 |
Stiles TL, Dickendesher TL, Gaultier A, Fernandez-Castaneda A, Mantuano E, Giger RJ, Gonias SL. LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin. Journal of Cell Science. 126: 209-20. PMID 23132925 DOI: 10.1242/Jcs.113191 |
0.392 |
|
2013 |
Bristow JM, Reno TA, Jo M, Gonias SL, Klemke RL. Dynamic phosphorylation of tyrosine 665 in pseudopodium-enriched atypical kinase 1 (PEAK1) is essential for the regulation of cell migration and focal adhesion turnover. The Journal of Biological Chemistry. 288: 123-31. PMID 23105102 DOI: 10.1074/Jbc.M112.410910 |
0.338 |
|
2013 |
Agarwal M, Nitta R, Dovat S, Li G, Arita H, Narita Y, Fukushima S, Tateishi K, Matsushita Y, Yoshida A, Miyakita Y, Ohno M, Collins VP, Kawahara N, Shibui S, ... ... Gonias SL, et al. CELL BIOLOGY AND SIGNALING Neuro-Oncology. 15: iii12-iii31. DOI: 10.1093/Neuonc/Not174 |
0.587 |
|
2012 |
Eastman BM, Jo M, Webb DL, Takimoto S, Gonias SL. A transformation in the mechanism by which the urokinase receptor signals provides a selection advantage for estrogen receptor-expressing breast cancer cells in the absence of estrogen. Cellular Signalling. 24: 1847-55. PMID 22617030 DOI: 10.1016/J.Cellsig.2012.05.011 |
0.798 |
|
2011 |
Mantuano E, Henry K, Yamauchi T, Hiramatsu N, Yamauchi K, Orita S, Takahashi K, Lin JH, Gonias SL, Campana WM. The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13376-85. PMID 21940431 DOI: 10.1523/Jneurosci.2850-11.2011 |
0.388 |
|
2011 |
Hu J, Jo M, Cavenee WK, Furnari F, VandenBerg SR, Gonias SL. Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 15984-9. PMID 21896743 DOI: 10.1073/Pnas.1113416108 |
0.675 |
|
2011 |
Gonias SL, Gaultier A, Jo M. Regulation of the urokinase receptor (uPAR) by LDL receptor-related protein-1 (LRP1). Current Pharmaceutical Design. 17: 1962-9. PMID 21711236 DOI: 10.2174/138161211796718224 |
0.466 |
|
2011 |
Endsley MP, Hu Y, Deng Y, He X, Warejcka DJ, Twining SS, Gonias SL, Zhang M. Maspin, the molecular bridge between the plasminogen activator system and beta1 integrin that facilitates cell adhesion. The Journal of Biological Chemistry. 286: 24599-607. PMID 21606500 DOI: 10.1074/Jbc.M111.235788 |
0.398 |
|
2011 |
Shi Y, Yamauchi T, Gaultier A, Takimoto S, Campana WM, Gonias SL. Regulation of cytokine expression by Schwann cells in response to α2-macroglobulin binding to LRP1. Journal of Neuroscience Research. 89: 544-51. PMID 21290408 DOI: 10.1002/Jnr.22576 |
0.419 |
|
2010 |
Jo M, Eastman BM, Webb DL, Stoletov K, Klemke R, Gonias SL. Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Cancer Research. 70: 8948-58. PMID 20940399 DOI: 10.1158/0008-5472.Can-10-1936 |
0.788 |
|
2010 |
Gaultier A, Simon G, Niessen S, Dix M, Takimoto S, Cravatt BF, Gonias SL. LDL receptor-related protein 1 regulates the abundance of diverse cell-signaling proteins in the plasma membrane proteome. Journal of Proteome Research. 9: 6689-95. PMID 20919742 DOI: 10.1021/Pr1008288 |
0.405 |
|
2010 |
Gorovoy M, Gaultier A, Campana WM, Firestein GS, Gonias SL. Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages. Journal of Leukocyte Biology. 88: 769-78. PMID 20610799 DOI: 10.1189/Jlb.0410220 |
0.432 |
|
2010 |
Gonias SL. Factor XII bridges coagulation and fibrinolysis again. Blood. 115: 4979-80. PMID 20558624 DOI: 10.1182/Blood-2010-03-275263 |
0.381 |
|
2010 |
Mantuano E, Jo M, Gonias SL, Campana WM. Low density lipoprotein receptor-related protein (LRP1) regulates Rac1 and RhoA reciprocally to control Schwann cell adhesion and migration. The Journal of Biological Chemistry. 285: 14259-66. PMID 20197276 DOI: 10.1074/Jbc.M109.085126 |
0.492 |
|
2010 |
Gaultier A, Hollister M, Reynolds I, Hsieh EH, Gonias SL. LRP1 regulates remodeling of the extracellular matrix by fibroblasts. Matrix Biology : Journal of the International Society For Matrix Biology. 29: 22-30. PMID 19699300 DOI: 10.1016/J.Matbio.2009.08.003 |
0.372 |
|
2009 |
Green CE, Liu T, Montel V, Hsiao G, Lester RD, Subramaniam S, Gonias SL, Klemke RL. Chemoattractant signaling between tumor cells and macrophages regulates cancer cell migration, metastasis and neovascularization. Plos One. 4: e6713. PMID 19696929 DOI: 10.1371/Journal.Pone.0006713 |
0.369 |
|
2009 |
Jo M, Lester RD, Montel V, Eastman B, Takimoto S, Gonias SL. Reversibility of epithelial-mesenchymal transition (EMT) induced in breast cancer cells by activation of urokinase receptor-dependent cell signaling. The Journal of Biological Chemistry. 284: 22825-33. PMID 19546228 DOI: 10.1074/Jbc.M109.023960 |
0.798 |
|
2009 |
Jo M, Takimoto S, Montel V, Gonias SL. The urokinase receptor promotes cancer metastasis independently of urokinase-type plasminogen activator in mice. The American Journal of Pathology. 175: 190-200. PMID 19497996 DOI: 10.2353/Ajpath.2009.081053 |
0.476 |
|
2009 |
Shi Y, Mantuano E, Inoue G, Campana WM, Gonias SL. Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway. Science Signaling. 2: ra18. PMID 19401592 DOI: 10.1126/Scisignal.2000188 |
0.433 |
|
2009 |
Gaultier A, Wu X, Le Moan N, Takimoto S, Mukandala G, Akassoglou K, Campana WM, Gonias SL. Low-density lipoprotein receptor-related protein 1 is an essential receptor for myelin phagocytosis. Journal of Cell Science. 122: 1155-62. PMID 19299462 DOI: 10.1242/Jcs.040717 |
0.366 |
|
2008 |
Mantuano E, Inoue G, Li X, Takahashi K, Gaultier A, Gonias SL, Campana WM. The hemopexin domain of matrix metalloproteinase-9 activates cell signaling and promotes migration of schwann cells by binding to low-density lipoprotein receptor-related protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11571-82. PMID 18987193 DOI: 10.1523/Jneurosci.3053-08.2008 |
0.404 |
|
2008 |
Galliano MF, Toulza E, Jonca N, Gonias SL, Serre G, Guerrin M. Binding of alpha2ML1 to the low density lipoprotein receptor-related protein 1 (LRP1) reveals a new role for LRP1 in the human epidermis. Plos One. 3: e2729. PMID 18648652 DOI: 10.1371/Journal.Pone.0002729 |
0.394 |
|
2008 |
Gonias SL. Urokinase: the identity crisis continues. Blood. 112: 8. PMID 18574039 DOI: 10.1182/Blood-2008-03-146910 |
0.336 |
|
2008 |
Mantuano E, Mukandala G, Li X, Campana WM, Gonias SL. Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling. The Journal of Biological Chemistry. 283: 19904-11. PMID 18499670 DOI: 10.1074/Jbc.M801762200 |
0.473 |
|
2008 |
Gaultier A, Arandjelovic S, Niessen S, Overton CD, Linton MF, Fazio S, Campana WM, Cravatt BF, Gonias SL. Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor. Blood. 111: 5316-25. PMID 18369152 DOI: 10.1182/Blood-2007-12-127613 |
0.465 |
|
2008 |
Gaultier A, Arandjelovic S, Li X, Janes J, Dragojlovic N, Zhou GP, Dolkas J, Myers RR, Gonias SL, Campana WM. A shed form of LDL receptor-related protein-1 regulates peripheral nerve injury and neuropathic pain in rodents. The Journal of Clinical Investigation. 118: 161-72. PMID 18060043 DOI: 10.1172/Jci32371 |
0.348 |
|
2007 |
Stoletov K, Montel V, Lester RD, Gonias SL, Klemke R. High-resolution imaging of the dynamic tumor cell-vascular interface in transparent zebrafish Proceedings of the National Academy of Sciences of the United States of America. 104: 17406-17411. PMID 17954920 DOI: 10.1073/Pnas.0703446104 |
0.367 |
|
2007 |
Montel V, Gaultier A, Lester RD, Campana WM, Gonias SL. The low-density lipoprotein receptor-related protein regulates cancer cell survival and metastasis development. Cancer Research. 67: 9817-24. PMID 17942912 DOI: 10.1158/0008-5472.Can-07-0683 |
0.482 |
|
2007 |
Arandjelovic S, Dragojlovic N, Li X, Myers RR, Campana WM, Gonias SL. A derivative of the plasma protease inhibitor alpha(2)-macroglobulin regulates the response to peripheral nerve injury. Journal of Neurochemistry. 103: 694-705. PMID 17725582 DOI: 10.1111/J.1471-4159.2007.04800.X |
0.366 |
|
2007 |
Lester RD, Jo M, Montel V, Takimoto S, Gonias SL. uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells. The Journal of Cell Biology. 178: 425-36. PMID 17664334 DOI: 10.1083/Jcb.200701092 |
0.453 |
|
2007 |
Luo JL, Tan W, Ricono JM, Korchynskyi O, Zhang M, Gonias SL, Cheresh DA, Karin M. Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin. Nature. 446: 690-4. PMID 17377533 DOI: 10.1038/Nature05656 |
0.363 |
|
2007 |
Jo M, Thomas KS, Takimoto S, Gaultier A, Hsieh EH, Lester RD, Gonias SL. Urokinase receptor primes cells to proliferate in response to epidermal growth factor. Oncogene. 26: 2585-94. PMID 17043637 DOI: 10.1038/Sj.Onc.1210066 |
0.485 |
|
2006 |
Campana WM, Li X, Dragojlovic N, Janes J, Gaultier A, Gonias SL. The low-density lipoprotein receptor-related protein is a pro-survival receptor in Schwann cells: possible implications in peripheral nerve injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11197-207. PMID 17065459 DOI: 10.1523/Jneurosci.2709-06.2006 |
0.429 |
|
2006 |
Arandjelovic S, Van Sant CL, Gonias SL. Limited mutations in full-length tetrameric human alpha2-macroglobulin abrogate binding of platelet-derived growth factor-BB and transforming growth factor-beta1. The Journal of Biological Chemistry. 281: 17061-8. PMID 16641085 DOI: 10.1074/Jbc.M602217200 |
0.351 |
|
2006 |
Gaultier A, Salicioni AM, Arandjelovic S, Gonias SL. Regulation of the composition of the extracellular matrix by low density lipoprotein receptor-related protein-1: activities based on regulation of mRNA expression. The Journal of Biological Chemistry. 281: 7332-40. PMID 16407289 DOI: 10.1074/Jbc.M511857200 |
0.412 |
|
2006 |
Hu K, Yang J, Tanaka S, Gonias SL, Mars WM, Liu Y. Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression. The Journal of Biological Chemistry. 281: 2120-7. PMID 16303771 DOI: 10.1074/Jbc.M504988200 |
0.398 |
|
2006 |
Gonias S, Jo M, Montel V, Lester R. ID: 300 Urokinase Receptor-dependent Cell Signaling Journal of Thrombosis and Haemostasis. 4: 49-49. DOI: 10.1111/j.1538-7836.2006.00300.x |
0.309 |
|
2005 |
Lester RD, Jo M, Campana WM, Gonias SL. Erythropoietin promotes MCF-7 breast cancer cell migration by an ERK/mitogen-activated protein kinase-dependent pathway and is primarily responsible for the increase in migration observed in hypoxia. The Journal of Biological Chemistry. 280: 39273-7. PMID 16207704 DOI: 10.1074/Jbc.M509446200 |
0.463 |
|
2005 |
Wu L, Gonias SL. The low-density lipoprotein receptor-related protein-1 associates transiently with lipid rafts. Journal of Cellular Biochemistry. 96: 1021-33. PMID 16149055 DOI: 10.1002/Jcb.20596 |
0.38 |
|
2005 |
Arandjelovic S, Hall BD, Gonias SL. Mutation of lysine 1370 in full-length human alpha2-macroglobulin blocks binding to the low density lipoprotein receptor-related protein-1. Archives of Biochemistry and Biophysics. 438: 29-35. PMID 15910735 DOI: 10.1016/J.Abb.2005.03.019 |
0.422 |
|
2005 |
Mars WM, Jo M, Gonias SL. Activation of hepatocyte growth factor by urokinase-type plasminogen activator is ionic strength-dependent. The Biochemical Journal. 390: 311-5. PMID 15869463 DOI: 10.1042/Bj20042028 |
0.312 |
|
2005 |
Li X, Gonias SL, Campana WM. Schwann cells express erythropoietin receptor and represent a major target for Epo in peripheral nerve injury. Glia. 51: 254-65. PMID 15812815 DOI: 10.1002/Glia.20202 |
0.427 |
|
2005 |
Jo M, Thomas KS, Marozkina N, Amin TJ, Silva CM, Parsons SJ, Gonias SL. Dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex determines the mitogenic activity of urokinase-type plasminogen activator. The Journal of Biological Chemistry. 280: 17449-57. PMID 15728176 DOI: 10.1074/Jbc.M413141200 |
0.487 |
|
2005 |
Bhattacharjee G, Arandjelovic S, Mackman N, Gonias SL, Edgington TS. Enhancement of Tissue Factor Dependent Procoagulant Activity and Factor Xa Generation by Alpha2-Macroglobulin. Blood. 106: 1941-1941. DOI: 10.1182/Blood.V106.11.1941.1941 |
0.471 |
|
2004 |
Wu L, Arandjelovic S, Gonias SL. Effects of low density lipoprotein receptor-related protein-1 on the expression of platelet-derived growth factor beta-receptor in vitro. Journal of Cellular Biochemistry. 93: 1169-77. PMID 15486970 DOI: 10.1002/Jcb.20288 |
0.411 |
|
2004 |
Gonias SL, Wu L, Salicioni AM. Low density lipoprotein receptor-related protein: regulation of the plasma membrane proteome. Thrombosis and Haemostasis. 91: 1056-64. PMID 15175790 DOI: 10.1160/Th04-01-0023 |
0.402 |
|
2004 |
Salicioni AM, Gaultier A, Brownlee C, Cheezum MK, Gonias SL. Low density lipoprotein receptor-related protein-1 promotes beta1 integrin maturation and transport to the cell surface. The Journal of Biological Chemistry. 279: 10005-12. PMID 14699139 DOI: 10.1074/Jbc.M306625200 |
0.365 |
|
2003 |
Hope C, Mettenburg J, Gonias SL, DeKosky ST, Kamboh MI, Chu CT. Functional analysis of plasma alpha(2)-macroglobulin from Alzheimer's disease patients with the A2M intronic deletion. Neurobiology of Disease. 14: 504-12. PMID 14678766 DOI: 10.1016/J.Nbd.2003.08.005 |
0.323 |
|
2003 |
Jo M, Thomas KS, Wu L, Gonias SL. Soluble urokinase-type plasminogen activator receptor inhibits cancer cell growth and invasion by direct urokinase-independent effects on cell signaling. The Journal of Biological Chemistry. 278: 46692-8. PMID 12963722 DOI: 10.1074/Jbc.M308808200 |
0.478 |
|
2003 |
Mathew S, Arandjelovic S, Beyer WF, Gonias SL, Pizzo SV. Characterization of the interaction between alpha2-macroglobulin and fibroblast growth factor-2: the role of hydrophobic interactions. The Biochemical Journal. 374: 123-9. PMID 12755687 DOI: 10.1042/Bj20021655 |
0.32 |
|
2003 |
Arandjelovic S, Freed TA, Gonias SL. Growth factor-binding sequence in human alpha2-macroglobulin targets the receptor-binding site in transforming growth factor-beta. Biochemistry. 42: 6121-7. PMID 12755614 DOI: 10.1021/Bi0342158 |
0.346 |
|
2003 |
Jo M, Thomas KS, O'Donnell DM, Gonias SL. Epidermal growth factor receptor-dependent and -independent cell-signaling pathways originating from the urokinase receptor. The Journal of Biological Chemistry. 278: 1642-6. PMID 12426305 DOI: 10.1074/Jbc.M210877200 |
0.441 |
|
2002 |
Ma Z, Thomas KS, Webb DJ, Moravec R, Salicioni AM, Mars WM, Gonias SL. Regulation of Rac1 activation by the low density lipoprotein receptor-related protein. The Journal of Cell Biology. 159: 1061-70. PMID 12499359 DOI: 10.1083/Jcb.200207070 |
0.494 |
|
2002 |
Salicioni AM, Mizelle KS, Loukinova E, Mikhailenko I, Strickland DK, Gonias SL. The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces. The Journal of Biological Chemistry. 277: 16160-6. PMID 11867643 DOI: 10.1074/Jbc.M201401200 |
0.472 |
|
2002 |
Strickland DK, Gonias SL, Argraves WS. Diverse roles for the LDL receptor family. Trends in Endocrinology and Metabolism: Tem. 13: 66-74. PMID 11854021 DOI: 10.1016/S1043-2760(01)00526-4 |
0.321 |
|
2002 |
Mettenburg JM, Webb DJ, Gonias SL. Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors. The Journal of Biological Chemistry. 277: 13338-45. PMID 11823454 DOI: 10.1074/Jbc.M106792200 |
0.33 |
|
2002 |
Jo M, Thomas KS, Somlyo AV, Somlyo AP, Gonias SL. Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration. The Journal of Biological Chemistry. 277: 12479-85. PMID 11805108 DOI: 10.1074/Jbc.M111147200 |
0.441 |
|
2001 |
Webb DJ, Thomas KS, Gonias SL. Plasminogen activator inhibitor 1 functions as a urokinase response modifier at the level of cell signaling and thereby promotes MCF-7 cell growth. The Journal of Cell Biology. 152: 741-52. PMID 11266465 DOI: 10.1083/Jcb.152.4.741 |
0.452 |
|
2000 |
Webb DJ, Roadcap DW, Dhakephalkar A, Gonias SL. A 16-amino acid peptide from human alpha2-macroglobulin binds transforming growth factor-beta and platelet-derived growth factor-BB. Protein Science : a Publication of the Protein Society. 9: 1986-92. PMID 11106172 DOI: 10.1110/Ps.9.10.1986 |
0.302 |
|
2000 |
Nguyen DH, Webb DJ, Catling AD, Song Q, Dhakephalkar A, Weber MJ, Ravichandran KS, Gonias SL. Urokinase-type plasminogen activator stimulates the Ras/Extracellular signal-regulated kinase (ERK) signaling pathway and MCF-7 cell migration by a mechanism that requires focal adhesion kinase, Src, and Shc. Rapid dissociation of GRB2/Sps-Shc complex is associated with the transient phosphorylation of ERK in urokinase-treated cells. The Journal of Biological Chemistry. 275: 19382-8. PMID 10777511 DOI: 10.1074/Jbc.M909575199 |
0.416 |
|
2000 |
Gonias SL, Carmichael A, Mettenburg JM, Roadcap DW, Irvin WP, Webb DJ. Identical or overlapping sequences in the primary structure of human alpha(2)-macroglobulin are responsible for the binding of nerve growth factor-beta, platelet-derived growth factor-BB, and transforming growth factor-beta. The Journal of Biological Chemistry. 275: 5826-31. PMID 10681572 DOI: 10.1074/Jbc.275.8.5826 |
0.326 |
|
1999 |
Nguyen DH, Catling AD, Webb DJ, Sankovic M, Walker LA, Somlyo AV, Weber MJ, Gonias SL. Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner. The Journal of Cell Biology. 146: 149-64. PMID 10402467 DOI: 10.1083/Jcb.146.1.149 |
0.412 |
|
1999 |
Hussaini IM, Brown MD, Weaver AM, Carpenter J, Karns LR, Vandenberg SR, Gonias SL. Stable antisense RNA expression neutralizes the activity of low-density lipoprotein receptor-related protein and promotes urokinase accumulation in the medium of an astrocytic tumor cell line. Antisense & Nucleic Acid Drug Development. 9: 183-90. PMID 10355824 DOI: 10.1089/Oli.1.1999.9.183 |
0.662 |
|
1999 |
Webb DJ, Nguyen DH, Sankovic M, Gonias SL. The very low density lipoprotein receptor regulates urokinase receptor catabolism and breast cancer cell motility in vitro. The Journal of Biological Chemistry. 274: 7412-20. PMID 10066806 DOI: 10.1074/Jbc.274.11.7412 |
0.478 |
|
1999 |
Kralovich KR, Li L, Hembrough TA, Webb DJ, Karns LR, Gonias SL. Characterization of the binding sites for plasminogen and tissue-type plasminogen activator in cytokeratin 8 and cytokeratin 18. Journal of Protein Chemistry. 17: 845-54. PMID 9988531 DOI: 10.1023/A:1020738620817 |
0.35 |
|
1999 |
Hussaini IM, Brown MD, Karns LR, Carpenter J, Redpath GT, Gonias SL, Vandenberg SR. Epidermal growth factor differentially regulates low density lipoprotein receptor-related protein gene expression in neoplastic and fetal human astrocytes. Glia. 25: 71-84. PMID 9888299 DOI: 10.1002/(Sici)1098-1136(19990101)25:1<71::Aid-Glia7>3.0.Co;2-0 |
0.653 |
|
1998 |
Nguyen DH, Hussaini IM, Gonias SL. Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility. The Journal of Biological Chemistry. 273: 8502-7. PMID 9525964 DOI: 10.1074/Jbc.273.14.8502 |
0.468 |
|
1998 |
Lysiak JJ, Hussaini IM, Gonias SL. alpha 2-Macroglobulin synthesis by the human monocytic cell line THP-1 is differentiation state-dependent. Journal of Cellular Biochemistry. 67: 492-7. PMID 9383708 DOI: 10.1002/(Sici)1097-4644(19971215)67:4<492::Aid-Jcb7>3.0.Co;2-N |
0.394 |
|
1997 |
Weaver AM, Hussaini IM, Mazar A, Henkin J, Gonias SL. Embryonic fibroblasts that are genetically deficient in low density lipoprotein receptor-related protein demonstrate increased activity of the urokinase receptor system and accelerated migration on vitronectin Journal of Biological Chemistry. 272: 14372-14379. PMID 9162074 DOI: 10.1074/Jbc.272.22.14372 |
0.457 |
|
1997 |
Brown MD, Banker GA, Hussaini IM, Gonias SL, VandenBerg SR. Low density lipoprotein receptor-related protein is expressed early and becomes restricted to a somatodendritic domain during neuronal differentiation in culture. Brain Research. 747: 313-7. PMID 9046007 DOI: 10.1016/S0006-8993(96)01321-2 |
0.567 |
|
1996 |
Webb DJ, Weaver AM, Atkins-Brady TL, Gonias SL. Proteinases are isoform-specific regulators of the binding of transforming growth factor β to α2-macroglobulin Biochemical Journal. 320: 551-555. PMID 8973565 DOI: 10.1042/Bj3200551 |
0.331 |
|
1996 |
Hembrough TA, Li L, Gonias SL. Cell-surface cytokeratin 8 is the major plasminogen receptor on breast cancer cells and is required for the accelerated activation of cell-associated plasminogen by tissue-type plasminogen activator. The Journal of Biological Chemistry. 271: 25684-91. PMID 8810346 DOI: 10.1074/Jbc.271.41.25684 |
0.455 |
|
1996 |
Webb DJ, Wen J, Lysiak JJ, Umans L, Van Leuven F, Gonias SL. Murine alpha-macroglobulins demonstrate divergent activities as neutralizers of transforming growth factor-beta and as inducers of nitric oxide synthesis. A possible mechanism for the endotoxin insensitivity of the alpha2-macroglobulin gene knock-out mouse. The Journal of Biological Chemistry. 271: 24982-8. PMID 8798779 DOI: 10.1074/Jbc.271.40.24982 |
0.309 |
|
1996 |
Weaver AM, McCabe M, Kim I, Allietta MM, Gonias SL. Epidermal growth factor and platelet-derived growth factor-BB induce a stable increase in the activity of low density lipoprotein receptor-related protein in vascular smooth muscle cells by altering receptor distribution and recycling Journal of Biological Chemistry. 271: 24894-24900. PMID 8798766 DOI: 10.1074/Jbc.271.40.24894 |
0.441 |
|
1996 |
Hembrough TA, Kralovich KR, Li L, Gonias SL. Cytokeratin 8 released by breast carcinoma cells in vitro binds plasminogen and tissue-type plasminogen activator and promotes plasminogen activation. The Biochemical Journal. 763-9. PMID 8760360 DOI: 10.1042/Bj3170763 |
0.417 |
|
1996 |
Hussaini IM, LaMarre J, Lysiak JJ, Karns LR, VandenBerg SR, Gonias SL. Transcriptional regulation of LDL receptor-related protein by IFN-gamma and the antagonistic activity of TGF-beta(1) in the RAW 264.7 macrophage-like cell line. Journal of Leukocyte Biology. 59: 733-9. PMID 8656060 DOI: 10.1002/Jlb.59.5.733 |
0.596 |
|
1996 |
Webb DJ, Crookston KP, Figler NL, Lamarre J, Gonias SL. Differences in the binding of transforming growth factor beta 1 to the acute-phase reactant and constitutively synthesized alpha-macroglobulins of rat. The Biochemical Journal. 579-86. PMID 8526873 DOI: 10.1042/Bj3120579 |
0.321 |
|
1995 |
Webb DJ, Hussaini IM, Weaver AM, Atkins TL, Chu CT, Pizzo SV, Owens GK, Gonias SL. Activated alpha 2-macroglobulin promotes mitogenesis in rat vascular smooth muscle cells by a mechanism that is independent of growth-factor-carrier activity. European Journal of Biochemistry / Febs. 234: 714-22. PMID 8575427 DOI: 10.1111/J.1432-1033.1995.714_A.X |
0.378 |
|
1995 |
Weaver AM, Owens GK, Gonias SL. Native and activated forms of α2-macroglobulin increase expression of platelet-derived growth factor α-receptor in vascular smooth muscle cells: Evidence for autocrine transforming growth factor-β activity Journal of Biological Chemistry. 270: 30741-30748. PMID 8530514 DOI: 10.1074/Jbc.270.51.30741 |
0.414 |
|
1995 |
Niemuller CA, Randall KJ, Webb DJ, Gonias SL, Lamarre J. α2-macroglobulin conformation determines binding affinity for activin A and plasma clearance of activin A/α2-macroglobulin complex Endocrinology. 136: 5343-5349. PMID 7588280 DOI: 10.1210/Endo.136.12.7588280 |
0.324 |
|
1995 |
Lysiak JJ, Hussaini IM, Webb DJ, Glass WF, Allietta M, Gonias SL. Alpha 2-macroglobulin functions as a cytokine carrier to induce nitric oxide synthesis and cause nitric oxide-dependent cytotoxicity in the RAW 264.7 macrophage cell line. The Journal of Biological Chemistry. 270: 21919-27. PMID 7545171 DOI: 10.1074/Jbc.270.37.21919 |
0.38 |
|
1995 |
Wolf BB, Gonias SL. Neurotrophin binding to human alpha 2-macroglobulin under apparent equilibrium conditions. Biochemistry. 33: 11270-7. PMID 7537086 DOI: 10.1021/Bi00203A024 |
0.321 |
|
1994 |
Lopes MB, Bogaev CA, Gonias SL, VandenBerg SR. Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells. Febs Letters. 338: 301-5. PMID 8307199 DOI: 10.1016/0014-5793(94)80288-2 |
0.61 |
|
1994 |
Turner JS, Redpath GT, Humphries JE, Gonias SL, Vandenberg SR. Plasmin modulates the thrombin-evoked calcium response in C6 glioma cells. The Biochemical Journal. 297: 175-9. PMID 8280096 DOI: 10.1042/Bj2970175 |
0.584 |
|
1994 |
Lamarre J, Vasudevan J, Gonias SL. Plasmin cleaves betaglycan and releases a 60 kDa transforming growth factor-β complex from the cell surface Biochemical Journal. 302: 199-205. PMID 8068006 DOI: 10.1042/Bj3020199 |
0.343 |
|
1994 |
Gonias SL, LaMarre J, Crookston KP, Webb DJ, Wolf BB, Lopes MB, Moses HL, Hayes MA. Alpha 2-macroglobulin and the alpha 2-macroglobulin receptor/LRP. A growth regulatory axis. Annals of the New York Academy of Sciences. 737: 273-90. PMID 7524402 DOI: 10.1111/J.1749-6632.1994.Tb44318.X |
0.324 |
|
1994 |
Crookston KP, Gonias SL. The role of cysteine-949 in the binding of transforming growth factor-beta 1 and transforming growth factor-beta 2 to alpha 2-macroglobulin. Biochemical and Biophysical Research Communications. 200: 1578-85. PMID 7514405 DOI: 10.1006/Bbrc.1994.1631 |
0.309 |
|
1994 |
Humphries J, De La Cadena R, Atkins T, Colman R, Gonias S. Interaction of high molecular weight kininogen with plasminogen inhibits binding of plasminogen to cell surfaces Fibrinolysis. 8: 245-254. DOI: 10.1016/0268-9499(94)90050-7 |
0.34 |
|
1993 |
Vasudevan J, Humphries JE, Gonias SL. Binding of anisoylated Lys-plasminogen streptokinase activator complex to cells in culture Thrombosis and Haemostasis. 69: 370-374. PMID 8388580 DOI: 10.1055/S-0038-1651614 |
0.414 |
|
1993 |
Crookston KP, Webb DJ, Lamarre J, Gonias SL. Binding of platelet-derived growth factor-BB and transforming growth factor-β1 to α2-macroglobulin in vitro and in vivo: Comparison of receptor-recognized and non-recognized α2-macroglobulin conformations Biochemical Journal. 293: 443-450. PMID 7688216 DOI: 10.1042/Bj2930443 |
0.338 |
|
1993 |
LaMarre J, Wolf BB, Kittler ELW, Quesenberry PJ, Gonias SL. Regulation of macrophage α2-macroglobulin receptor/low density lipoprotein receptor-related protein by lipopolysaccharide and interferon-γ Journal of Clinical Investigation. 91: 1219-1224. PMID 7680664 DOI: 10.1172/Jci116283 |
0.369 |
|
1993 |
Anonick PK, Yoo JK, Webb DJ, Gonias SL. Characterization of the antiplasmin activity of human thrombospondin-1 in solution Biochemical Journal. 289: 903-909. PMID 7679575 DOI: 10.1042/Bj2890903 |
0.34 |
|
1993 |
Humphries JE, Vasudevan J, Gonias SL. Fibrinogenolytic and fibrinolytic activity of cell-associated plasmin Arteriosclerosis and Thrombosis. 13: 48-55. PMID 7678497 DOI: 10.1161/01.Atv.13.1.48 |
0.419 |
|
1992 |
Figler NL, Strickland DK, Allietta M, Gonias SL. Immunoelectron microscopy studies with a monoclonal antibody directed against a receptor recognition site epitope in human alpha 2-macroglobulin. Journal of Structural Biology. 106: 237-42. PMID 1725127 DOI: 10.1016/1047-8477(91)90073-6 |
0.309 |
|
1992 |
Anonick PK, Vasudevan J, Gonias SL. Antifibrinolytic activities of α-N-acetyl-L-lysine methyl ester, ε- aminocaproic acid, and tranexamic acid: Importance of kringle interactions and active site inhibition Arteriosclerosis and Thrombosis. 12: 708-716. PMID 1375508 DOI: 10.1161/01.Atv.12.6.708 |
0.324 |
|
1992 |
Webb DJ, Crookston KP, Hall SW, Gonias SL. Binding of transforming growth factor-beta 1 to immobilized human alpha 2-macroglobulin. Archives of Biochemistry and Biophysics. 292: 487-92. PMID 1370602 DOI: 10.1016/0003-9861(92)90020-W |
0.31 |
|
1991 |
Anonick PK, Gonias SL. Soluble fibrin preparations inhibit the reaction of plasmin with alpha 2-macroglobulin. Comparison with alpha 2-antiplasmin and leupeptin. The Biochemical Journal. 53-9. PMID 1708234 DOI: 10.1042/Bj2750053 |
0.308 |
|
1991 |
Enghild JJ, Thøgersen IB, Salvesen G, Fey GH, Figler NL, Gonias SL, Pizzo SV. Alpha-macroglobulin from Limulus polyphemus exhibits proteinase inhibitory activity and participates in a hemolytic system. Biochemistry. 29: 10070-80. PMID 1703001 DOI: 10.1021/Bi00495A009 |
0.325 |
|
1991 |
LaMarre J, Hayes MA, Wollenberg GK, Hussaini I, Hall SW, Gonias SL. An α2-macroglobulin receptor-dependent mechanism for the plasma clearance of transforming growth factor-β1 in mice Journal of Clinical Investigation. 87: 39-44. PMID 1702100 DOI: 10.1172/Jci114998 |
0.329 |
|
1991 |
Humphries J, Hall S, VandenBerg S, Gonias S. Streptokinase-plasmin complex binds to plasminogen receptors on rat hepatocytes and human endothelium Fibrinolysis. 5: 171-176. DOI: 10.1016/0268-9499(91)90019-Z |
0.601 |
|
1990 |
Anonick PK, Wolf B, Gonias SL. Regulation of plasmin, miniplasmin, and streptokinase-plasmin complex by alpha 2-antiplasmin, alpha 2-macroglobulin, and antithrombin III in the presence of heparin. Thrombosis Research. 59: 449-62. PMID 1700488 DOI: 10.1016/0049-3848(90)90406-3 |
0.323 |
|
1990 |
Hussaini IM, Figler NL, Gonias SL. The structure of alpha 2-macroglobulin-methylamine after papain digestion as determined by electron microscopy. The Biochemical Journal. 270: 291-5. PMID 1698054 DOI: 10.1042/Bj2700291 |
0.315 |
|
1990 |
Hall SW, VandenBerg SR, Gonias SL. Plasminogen carbohydrate side chains in receptor binding and enzyme activation: a study of C6 glioma cells and primary cultures of rat hepatocytes. Journal of Cellular Biochemistry. 43: 213-27. PMID 1696276 DOI: 10.1002/Jcb.240430303 |
0.619 |
|
1990 |
Keohane ME, Hall SW, VandenBerg SR, Gonias SL. Secretion of alpha 2-macroglobulin, alpha 2-antiplasmin, and plasminogen activator inhibitor-1 by glioblastoma multiforme in primary organ culture. Journal of Neurosurgery. 73: 234-41. PMID 1694891 DOI: 10.3171/Jns.1990.73.2.0234 |
0.571 |
|
1989 |
VandenBerg SR, Gonias SL. Covalent complexes of albumin with serotonin, ketanserin and lysergic acid antagonize the activity of serotonin in human platelets. Life Sciences. 44: 1777-85. PMID 2733551 DOI: 10.1016/0024-3205(89)90565-1 |
0.511 |
|
1989 |
VandenBerg SR, Britt SG, Redpath GT, Gonias SL. 5-Hydroxytryptamine2 (5-HT2) structure-function relationships of the nitro and amino phenylpiperazines on intact human platelets. Biochemical Pharmacology. 38: 4237-44. PMID 2597195 DOI: 10.1016/0006-2952(89)90521-2 |
0.55 |
|
1989 |
Hall SW, Braud LL, Gonias SL. Binding of bovine, ovine, porcine, canine, and rat plasminogen to rat hepatocytes and rat C6 glioma cells in vitro. Biochemical and Biophysical Research Communications. 164: 1288-94. PMID 2556124 DOI: 10.1016/0006-291X(89)91809-3 |
0.346 |
|
1989 |
Hall SW, VandenBerg SR, Gonias SL. Expression of plasminogen receptors on C6 glioma cells. Brain Research. 495: 373-6. PMID 2548675 DOI: 10.1016/0006-8993(89)90231-X |
0.622 |
|
1989 |
Gonias SL, Braud LL, Geary WA, VandenBerg SR. Plasminogen binding to rat hepatocytes in primary culture and to thin slices of rat liver. Blood. 74: 729-36. PMID 2546631 DOI: 10.1182/Blood.V74.2.729.Bloodjournal742729 |
0.571 |
|
1989 |
Geary WA, Gonias SL. Inactivation of alpha 2-antiplasmin by limited reaction with cis-dichlorodiammineplatinum (II) Biochimica Et Biophysica Acta. 994: 1-6. PMID 2521201 DOI: 10.1016/0167-4838(89)90054-X |
0.303 |
|
1988 |
Pizzo SV, Swaim MW, Roche PA, Gonias SL. Selectivity and stereospecificity of the reactions of dichlorodiammineplatinum(II) with three purified plasma proteins. Journal of Inorganic Biochemistry. 33: 67-76. PMID 2454291 DOI: 10.1016/0162-0134(88)80035-7 |
0.309 |
|
1988 |
Gonias S, Figler N, Braud L. Regulation of streptokinase-human plasmin complex by the plasma proteinase inhibitors alpha 2-antiplasmin and alpha 2-macroglobulin is species specific and temperature dependent Blood. 72: 1658-1664. DOI: 10.1182/Blood.V72.5.1658.1658 |
0.316 |
|
1987 |
Pizzo SV, Roche PA, Feldman SR, Gonias SL. Further characterization of the platinum-reactive component of the alpha 2-macroglobulin-receptor recognition site. The Biochemical Journal. 238: 217-25. PMID 3026342 DOI: 10.1042/Bj2380217 |
0.345 |
|
1987 |
Pizzo SV, Rajagopalan S, Roche PA, Fuchs HE, Feldman SR, Gonias SL. Specificity of alpha 2-macroglobulin covalent cross-linking for the active domain of proteinases. Biological Chemistry Hoppe-Seyler. 367: 1177-82. PMID 2434119 DOI: 10.1515/Bchm3.1986.367.2.1177 |
0.31 |
|
1985 |
Rajagopalan S, Gonias SL, Pizzo SV. A nonantigenic covalent streptokinase-polyethylene glycol complex with plasminogen activator function. The Journal of Clinical Investigation. 75: 413-9. PMID 3156148 DOI: 10.1172/Jci111715 |
0.312 |
|
1984 |
Gonias SL, Pizzo SV. Chemical and structural modifications of alpha 2-macroglobulin: effects on receptor binding and endocytosis studied in an in vivo model. Annals of the New York Academy of Sciences. 421: 457-71. PMID 6202219 DOI: 10.1111/J.1749-6632.1983.Tb18139.X |
0.347 |
|
1984 |
Gonias SL, Pizzo SV. Reaction of human alpha 2-macroglobulin half-molecules with plasmin as a probe of protease binding site structure. Biochemistry. 22: 4933-40. PMID 6196052 DOI: 10.1021/Bi00290A009 |
0.302 |
|
1983 |
Beauchamp CO, Gonias SL, Menapace DP, Pizzo SV. A new procedure for the synthesis of polyethylene glycol-protein adducts; effects on function, receptor recognition, and clearance of superoxide dismutase, lactoferrin, and alpha 2-macroglobulin. Analytical Biochemistry. 131: 25-33. PMID 6193731 DOI: 10.1016/0003-2697(83)90131-8 |
0.337 |
|
1983 |
Gonias SL, Balber AE, Hubbard WJ, Pizzo SV. Ligand binding, conformational change and plasma elimination of human, mouse and rat alpha-macroglobulin proteinase inhibitors. The Biochemical Journal. 209: 99-105. PMID 6189480 DOI: 10.1042/Bj2090099 |
0.305 |
|
1982 |
Gonias SL, Einarsson M, Pizzo SV. Catabolic pathways for streptokinase, plasmin, and streptokinase activator complex in mice. In vivo reaction of plasminogen activator with alpha 2-macroglobulin. The Journal of Clinical Investigation. 70: 412-23. PMID 6178757 DOI: 10.1172/Jci110631 |
0.34 |
|
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