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Emmanuel J. Mignot - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Neuroscience Biology
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320 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Fromy P, Kremliovsky M, Mignot E, Aloia M, Berent J, Hasan F, Hwang D, Poon JL, Malcolm R, Miller C, Nawa W, Bakker J. Digital Measures Development: Lessons Learned from an Expert Workshop Addressing Cross-Therapeutic Area Measures of Sleep. Digital Biomarkers. 8: 132-139. PMID 39015515 DOI: 10.1159/000539253  0.353
2024 Tracey B, Culp M, Fabregas S, Mignot E, Buhl DL, Volfson D. Novel biomarkers derived from the Maintenance of Wakefulness Test as predictors of sleepiness and response to treatment. Sleep. PMID 38954525 DOI: 10.1093/sleep/zsae148  0.324
2024 Bandyopadhyay A, Oks M, Sun H, Prasad B, Rusk S, Jefferson F, Malkani RG, Haghayegh S, Sachdeva R, Hwang D, Agustsson J, Mignot E, Summers M, Fabbri D, Deak M, et al. Strengths, weaknesses, opportunities and threats of using AI-enabled technology in sleep medicine: a commentary. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. PMID 38533757 DOI: 10.5664/jcsm.11132  0.345
2024 Olsen M, Zeitzer JM, Richardson RN, Musgrave VH, Sorensen HBD, Mignot E, Jennum PJ. A deep transfer learning approach for sleep stage classification and sleep apnea detection using wrist-worn consumer sleep technologies. Ieee Transactions On Bio-Medical Engineering. PMID 38498753 DOI: 10.1109/TBME.2024.3378480  0.628
2024 Suh S, Lok R, Weed L, Cho A, Mignot E, Leary EB, Zeitzer JM. Fatigued but not sleepy? An empirical investigation of the differentiation between fatigue and sleepiness in sleep disorder patients in a cross-sectional study. Journal of Psychosomatic Research. 178: 111606. PMID 38359639 DOI: 10.1016/j.jpsychores.2024.111606  0.609
2023 Pizza F, Vignatelli L, Vandi S, Zenesini C, Biscarini F, Franceschini C, Antelmi E, Ingravallo F, Mignot E, Bruni O, Nobili L, Veggiotti P, Ferri R, Plazzi G. Role of Daytime Continuous Polysomnography in the Diagnosis of Pediatric Narcolepsy Type 1. Neurology. 102: e207815. PMID 38165365 DOI: 10.1212/WNL.0000000000207815  0.307
2023 Plante DT, Hagen EW, Barnet JH, Mignot E, Peppard PE. Prevalence and Course of Idiopathic Hypersomnia in the Wisconsin Sleep Cohort Study. Neurology. 102: e207994. PMID 38165322 DOI: 10.1212/WNL.0000000000207994  0.321
2023 Specht A, Kolosov G, Cederberg KLJ, Bueno F, Arrona-Palacios A, Pardilla-Delgado E, Ruiz-Herrera N, Zitting KM, Kramer A, Zeitzer JM, Czeisler CA, Duffy JF, Mignot E. Circadian protein expression patterns in healthy young adults. Sleep Health. PMID 38087675 DOI: 10.1016/j.sleh.2023.10.005  0.572
2023 Brink-Kjaer A, Winer J, Zeitzer JM, Sorensen HBD, Jennum P, Mignot E, During E. Fully Automated Detection of Isolated Rapid-Eye-Movement Sleep Behavior Disorder Using Actigraphy. Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference. 2023: 1-5. PMID 38083699 DOI: 10.1109/EMBC40787.2023.10341133  0.638
2023 Torstensen EW, Haubjerg Østerby NC, Kornum BR, Wanscher B, Mignot E, Barløse M, Jennum PJ. Repeated polysomnography and multiple sleep latency test in narcolepsy type 1 and other hypersomnolence disorders. Sleep Medicine. 110: 91-98. PMID 37544279 DOI: 10.1016/j.sleep.2023.07.029  0.359
2023 Gunter KM, Brink-Kjaer A, Mignot E, Sorensen HBD, During E, Jennum P. SViT: A Spectral Vision Transformer for the Detection of REM Sleep Behavior Disorder. Ieee Journal of Biomedical and Health Informatics. 27: 4285-4292. PMID 37402190 DOI: 10.1109/JBHI.2023.3292231  0.336
2023 Sum-Ping O, Mignot E. What Is Narcolepsy? Jama. PMID 37145499 DOI: 10.1001/jama.2023.5149  0.318
2023 During EH, Hernandez B, Miglis MG, Sum-Ping O, Hekmat A, Cahuas A, Ekelmans A, Yoshino F, Mignot E, Kushida CA. Sodium Oxybate in Treatment-Resistant REM Sleep Behavior Disorder. Sleep. PMID 37052688 DOI: 10.1093/sleep/zsad103  0.305
2023 Zahid AN, Jennum P, Mignot E, Sorensen HBD. MSED: A Multi-Modal Sleep Event Detection Model for Clinical Sleep Analysis. Ieee Transactions On Bio-Medical Engineering. PMID 37028083 DOI: 10.1109/TBME.2023.3252368  0.308
2023 Sun H, Ye E, Paixao L, Ganglberger W, Chu CJ, Zhang C, Rosand J, Mignot E, Cash SS, Gozal D, Thomas RJ, Westover MB. The sleep and wake electroencephalogram over the lifespan. Neurobiology of Aging. 124: 60-70. PMID 36739622 DOI: 10.1016/j.neurobiolaging.2023.01.006  0.354
2022 Pérez-Carbonell L, Mignot E, Leschziner G, Dauvilliers Y. Understanding and approaching excessive daytime sleepiness. Lancet (London, England). PMID 36115367 DOI: 10.1016/S0140-6736(22)01018-2  0.304
2022 Helge AW, Hanif U, Joergensen VH, Jennum P, Mignot E, Sorensen HBD. Detection of Cheyne-Stokes Breathing using a transformer-based neural network. Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference. 2022: 4580-4583. PMID 36086293 DOI: 10.1109/EMBC48229.2022.9871537  0.313
2022 Lane JM, Qian J, Mignot E, Redline S, Scheer FAJL, Saxena R. Genetics of circadian rhythms and sleep in human health and disease. Nature Reviews. Genetics. PMID 36028773 DOI: 10.1038/s41576-022-00519-z  0.356
2022 Evans R, Kimura H, Alexander R, Davies CH, Faessel H, Hartman DS, Ishikawa T, Ratti E, Shimizu K, Suzuki M, Tanaka S, Yukitake H, Dauvilliers Y, Mignot E. Orexin 2 receptor-selective agonist danavorexton improves narcolepsy phenotype in a mouse model and in human patients. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207531119. PMID 35994639 DOI: 10.1073/pnas.2207531119  0.35
2022 Cederberg KLJ, Hanif U, Peris Sempere V, Hédou J, Leary EB, Schneider LD, Lin L, Zhang J, Morse AM, Blackman A, Schweitzer PK, Kotagal S, Bogan R, Kushida CA, Ju YS, ... ... Mignot E, et al. Proteomic Biomarkers of the Apnea Hypopnea Index and Obstructive Sleep Apnea: Insights into the Pathophysiology of Presence, Severity, and Treatment Response. International Journal of Molecular Sciences. 23. PMID 35887329 DOI: 10.3390/ijms23147983  0.331
2022 Olsen M, Zeitzer JM, Richardson RN, Davidenko P, Jennum PJ, Sorensen HBD, Mignot E. A flexible deep learning architecture for temporal sleep stage classification using accelerometry and photoplethysmography. Ieee Transactions On Bio-Medical Engineering. PMID 35786544 DOI: 10.1109/TBME.2022.3187945  0.591
2022 Edelson JL, Schneider LD, Amar D, Brink-Kjaer A, Cederberg KL, Kutalik Z, Hagen EW, Peppard PE, Tempaku PF, Tufik S, Evans DS, Stone K, Tranah G, Cade B, Redline S, ... ... Mignot E, et al. The Genetic Etiology of Periodic Leg Movement in Sleep. Sleep. PMID 35670608 DOI: 10.1093/sleep/zsac121  0.365
2022 Pépin JL, Bailly S, Mignot E, Gaucher J, Chouraki A, Cals-Maurette M, Ben Messaoud R, Tamisier R, Arnal PJ. Digital markers of sleep architecture to characterize the impact of different lockdown regimens on sleep health during the COVID-19 pandemic. Sleep. 45. PMID 35429392 DOI: 10.1093/sleep/zsac074  0.356
2022 Dauvilliers Y, Arnulf I, Foldvary-Schaefer N, Morse AM, Šonka K, Thorpy MJ, Mignot E, Chandler P, Parvataneni R, Black J, Sterkel A, Chen D, Skobieranda F, Bogan RK. Safety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia: a phase 3, placebo-controlled, double-blind, randomised withdrawal study. The Lancet. Neurology. 21: 53-65. PMID 34942138 DOI: 10.1016/S1474-4422(21)00368-9  0.3
2021 Kjar MR, Brink-Kjar A, Hanif U, Mignot E, Jennum P, Sorensen HBD. Polysomnographic Plethysmography Excursions are Reduced in Obese Elderly Men. Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference. 2021: 2396-2399. PMID 34891764 DOI: 10.1109/EMBC46164.2021.9630145  0.343
2021 Maski K, Mignot E, Plazzi G, Dauvilliers Y. Disrupted nighttime sleep and sleep instability in narcolepsy. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. PMID 34463249 DOI: 10.5664/jcsm.9638  0.366
2021 Brink-Kjær A, Cesari M, Sixel-Döring F, Mollenhauer B, Trenkwalder C, Mignot E, Sorensen HBD, Jennum P. Arousal Characteristics in Patients with Parkinson's Disease and Isolated Rapid Eye Movement Sleep Behavior Disorder. Sleep. PMID 34214165 DOI: 10.1093/sleep/zsab167  0.343
2021 Mignot E, Zeitzer J, Pizza F, Plazzi G. Sleep Problems in Narcolepsy and the Role of Hypocretin/Orexin Deficiency. Frontiers of Neurology and Neuroscience. 45: 103-116. PMID 34052809 DOI: 10.1159/000514959  0.647
2021 Hanif UR, Leary EB, Schneider LD, Paulsen RR, Morse AM, Blackman A, Schweitzer PK, Kushida CA, Liu SY, Jennum P, Sorensen HBD, Mignot E. Estimation of Apnea-Hypopnea Index using Deep Learning on 3D Craniofacial Scans. Ieee Journal of Biomedical and Health Informatics. PMID 33961569 DOI: 10.1109/JBHI.2021.3078127  0.302
2021 Pépin JL, Bailly S, Mordret E, Gaucher J, Tamisier R, Ben Messaoud R, Arnal PJ, Mignot E. Greatest changes in objective sleep architecture during COVID-19 lockdown in night-owls with increased REM sleep. Sleep. PMID 33769511 DOI: 10.1093/sleep/zsab075  0.36
2021 Brink-Kjaer A, Christensen JAE, Cesari M, Mignot E, Sorensen HBD, Jennum P. Cortical arousal frequency is increased in narcolepsy type 1. Sleep. 44. PMID 33249455 DOI: 10.1093/sleep/zsaa255  0.362
2020 Cheung J, Leary EB, Lu H, Zeitzer JM, Mignot E. PSG Validation of minute-to-minute scoring for sleep and wake periods in a consumer wearable device. Plos One. 15: e0238464. PMID 32941498 DOI: 10.1371/Journal.Pone.0238464  0.57
2020 Olesen AN, Jennum PJ, Mignot E, Sorensen HBD. Automatic sleep stage classification with deep residual networks in a mixed-cohort setting. Sleep. 44. PMID 32844179 DOI: 10.1093/Sleep/Zsaa161  0.353
2020 Leary EB, Watson KT, Ancoli-Israel S, Redline S, Yaffe K, Ravelo LA, Peppard PE, Zou J, Goodman SN, Mignot E, Stone KL. Association of Rapid Eye Movement Sleep With Mortality in Middle-aged and Older Adults. Jama Neurology. PMID 32628261 DOI: 10.1001/Jamaneurol.2020.2108  0.426
2020 Ambati A, Ju YE, Lin L, Olesen AN, Koch H, Hedou JJ, Leary EB, Sempere VP, Mignot E, Taheri S. Proteomic biomarkers of sleep apnea. Sleep. PMID 32369590 DOI: 10.1093/Sleep/Zsaa086  0.437
2020 Brink-Kjaer A, Olesen AN, Peppard PE, Stone KL, Jennum P, Mignot E, Sorensen HBD. Automatic detection of cortical arousals in sleep and their contribution to daytime sleepiness. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 131: 1187-1203. PMID 32299002 DOI: 10.1016/J.Clinph.2020.02.027  0.401
2020 Mignot E. A harrowing journey through disordered sleep. Nature. 555: 26-27. PMID 32094901 DOI: 10.1038/d41586-018-02510-3  0.351
2020 Carvelli L, Olesen AN, Brink-Kjær A, Leary EB, Peppard PE, Mignot E, Sørensen HBD, Jennum P. Design of a deep learning model for automatic scoring of periodic and non-periodic leg movements during sleep validated against multiple human experts. Sleep Medicine. 69: 109-119. PMID 32062037 DOI: 10.1016/J.Sleep.2019.12.032  0.386
2020 Olesen AN, Chambon S, Thorey V, Jennum P, Mignot E, Sorensen HBD. Towards a Flexible Deep Learning Method for Automatic Detection of Clinically Relevant Multi-Modal Events in the Polysomnogram. Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference. 2019: 556-561. PMID 31945960 DOI: 10.1109/EMBC.2019.8856570  0.363
2020 Waeber A, Arnal P, Mignot E, Heinzer R. 0697 Early Sleep Apnea Termination By Bone-conducted Sound Stimulation Reduces Oxygen Desaturation Magnitude And Duration Sleep. 43. DOI: 10.1093/Sleep/Zsaa056.693  0.399
2020 Thybo J, Olesen AN, Olsen M, Leary E, Arnal P, Sørensen HB, Jennum P, Mignot E. 0451 Fully Automatic Detection of Sleep Disordered Breathing Events Sleep. 43. DOI: 10.1093/Sleep/Zsaa056.448  0.438
2020 Olsen M, Sorensen H, Jennum P, Mignot E. 1208 Sleep Stage Prediction And Sleep Disordered Breathing Detection Using Raw Actigraphy And Photoplethysmography From Wearable Consumer Device Sleep. 43. DOI: 10.1093/Sleep/Zsaa056.1202  0.455
2020 Leary EB, Watson KT, Ancoli-Israel S, Redline S, Yaffe K, Ravelo LA, Peppard PE, Zou J, Goodman S, Mignot E, Stone KL. 0048 The Association Between REM Sleep and Risk of Mortality in Three Independent Cohorts Sleep. 43: A19-A20. DOI: 10.1093/Sleep/Zsaa056.047  0.415
2019 Olsen M, Mignot E, Jennum PJ, Sorensen HBD. Robust, ECG-based algorithm for Sleep Disordered Breathing detection in large population-based cohorts using an automatic, data-driven approach. Sleep. PMID 31738833 DOI: 10.1093/Sleep/Zsz276  0.411
2019 Pizza F, Barateau L, Jaussent I, Vandi S, Antelmi E, Mignot E, Dauvilliers Y, Plazzi G. Validation of Multiple Sleep Latency Test for the diagnosis of pediatric narcolepsy type 1. Neurology. PMID 31405906 DOI: 10.1212/Wnl.0000000000008094  0.473
2019 Vandi S, Rodolfi S, Pizza F, Moresco M, Antelmi E, Ferri R, Mignot E, Plazzi G, Silvani A. Cardiovascular autonomic dysfunction, altered sleep architecture, and muscle overactivity during nocturnal sleep in pediatric patients with narcolepsy type 1. Sleep. PMID 31353416 DOI: 10.1093/Sleep/Zsz169  0.473
2019 Kim SJ, Kim S, Jeon S, Leary EB, Barwick F, Mignot E. Factors associated with fatigue in patients with insomnia. Journal of Psychiatric Research. 117: 24-30. PMID 31272015 DOI: 10.1016/J.Jpsychires.2019.06.021  0.395
2019 Hershman SG, Bot BM, Shcherbina A, Doerr M, Moayedi Y, Pavlovic A, Waggott D, Cho MK, Rosenberger ME, Haskell WL, Myers J, Champagne MA, Mignot E, Salvi D, Landray M, et al. Physical activity, sleep and cardiovascular health data for 50,000 individuals from the MyHeart Counts Study. Scientific Data. 6: 24. PMID 30975992 DOI: 10.1038/S41597-019-0016-7  0.308
2019 Chambon S, Thorey V, Arnal PJ, Mignot E, Gramfort A. DOSED: A deep learning approach to detect multiple sleep micro-events in EEG signal. Journal of Neuroscience Methods. 321: 64-78. PMID 30946878 DOI: 10.1016/J.Jneumeth.2019.03.017  0.35
2019 Hershner S, Dauvilliers Y, Chung F, Singh M, Wong J, Gali B, Kakkar R, Mignot E, Thorpy M, Auckley D. Knowledge Gaps in the Perioperative Management of Adults With Narcolepsy: A Call for Further Research. Anesthesia and Analgesia. PMID 30882519 DOI: 10.1213/Ane.0000000000004088  0.352
2019 Sakai N, Matsumura M, Lin L, Mignot E, Nishino S. HPLC analysis of CSF hypocretin-1 in type 1 and 2 narcolepsy. Scientific Reports. 9: 477. PMID 30679597 DOI: 10.1038/S41598-018-36942-8  0.319
2019 Roomkham S, Hittle M, Cheung J, Lovell D, Mignot E, Perrin D. Sleep monitoring with the Apple Watch: Comparison to a clinically validated actigraph F1000research. 8: 754. DOI: 10.12688/F1000Research.19020.1  0.476
2019 Leary EB, Seeger-Zybok RK, Mazurek M, Voronoy A, Lawlor B, Stephenson CL, Kushida C, Mignot E. 0322 Development of Complex Data Platform for the Stanford Technology Analytics and Genomics in Sleep (STAGES) Study Sleep. 42. DOI: 10.1093/Sleep/Zsz067.321  0.383
2019 Ambati A, Lin L, Zitting K, Duffy JF, Zeitzer J, Spiegel D, Czeisler CA, Mignot E. 0042 Proteomic Biomarkers Of Circadian Time Sleep. 42: A17-A18. DOI: 10.1093/Sleep/Zsz067.041  0.597
2019 Mignot E, Bogan RK, Black J, Parvataneni R, Menno D, Wang G, Dauvilliers Y. Effects of sodium oxybate treatment on sleep architecture in paediatric patients with narcolepsy Sleep Medicine. 64. DOI: 10.1016/J.Sleep.2019.11.715  0.455
2019 Leary EB, Watson KT, Ancoli-Israel S, Redline S, Yaffe K, Ravelo LA, Peppard PE, Zou J, Goodman SN, Mignot E, Stone KL. The association between rem sleep and mortality in the MrOs and wisconsin sleep cohorts Sleep Medicine. 64. DOI: 10.1016/J.Sleep.2019.11.595  0.466
2018 Stephansen JB, Olesen AN, Olsen M, Ambati A, Leary EB, Moore HE, Carrillo O, Lin L, Han F, Yan H, Sun YL, Dauvilliers Y, Scholz S, Barateau L, Hogl B, ... ... Mignot E, et al. Neural network analysis of sleep stages enables efficient diagnosis of narcolepsy. Nature Communications. 9: 5229. PMID 30523329 DOI: 10.1038/S41467-018-07229-3  0.475
2018 Leary EB, Moore HE, Schneider LD, Finn LA, Peppard PE, Mignot E. Periodic limb movements in sleep: Prevalence and associated sleepiness in the Wisconsin Sleep Cohort. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 129: 2306-2314. PMID 30243181 DOI: 10.1016/J.Clinph.2018.08.022  0.447
2018 Cheung J, Ruoff C, Moore H, Hagerman KA, Perez J, Sakamuri S, Warby SC, Mignot E, Day J, Sampson J. Increased EEG Theta Spectral Power in Sleep in Myotonic Dystrophy Type 1. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. PMID 29394960 DOI: 10.5664/Jcsm.6940  0.477
2018 Olsen M, Schneider LD, Cheung J, Peppard PE, Jennum PJ, Mignot E, Sorensen HBD. Automatic, ECG-based detection of autonomic arousals and their association with cortical arousals, leg movements, and respiratory events in sleep. Sleep. PMID 29329416 DOI: 10.1093/Sleep/Zsy006  0.401
2018 Cheung J, Zeitzer JM, Lu H, Mignot E. Validation of minute-to-minute scoring for sleep and wake periods in a consumer wearable device compared to an actigraphy device Sleep Science and Practice. 2. DOI: 10.1186/s41606-018-0029-8  0.567
2018 Jacobsen KP, Olesen AN, Trap L, Peppard PE, Sorensen HB, Jennum PJ, Mignot E. Automatic Detection of Respiratory Events During Sleep Using Bidirectional LSTM Networks Sleep. 41. DOI: 10.1093/Sleep/Zsy061.327  0.41
2018 Leary EB, Seeger-Zybok RK, Kushida C, Mignot E. 0324 Improving our Understanding of Sleep By Generating and Sharing a Large Sleep Cohort and Data Analytic Tools Sleep. 41. DOI: 10.1093/Sleep/Zsy061.323  0.471
2018 Carvelli L, Neergard Olesen A, Leary EB, Moore H, Schneider LD, Peppard PE, Jennum PJ, Sørensen HB, Mignot E. 0323 Design of a Deep Learning Based Algorithm forAutomatic Detection of Leg Movements During Sleep Sleep. 41: A124-A124. DOI: 10.1093/Sleep/Zsy061.322  0.375
2018 Olesen AN, Peppard PE, Sorensen HB, Jennum PJ, Mignot E. End-to-End Deep Learning Model For Automatic Sleep Staging Using Raw PSG Waveforms Sleep. 41. DOI: 10.1093/Sleep/Zsy061.315  0.395
2018 Brink-Kjaer A, Olesen AN, Jespersen CA, Peppard PE, Jennum PJ, Sorensen HB, Mignot E. Automatic Detection of Cortical Arousals in Sleep using Bi-direction LSTM Networks Sleep. 41. DOI: 10.1093/Sleep/Zsy061.141  0.414
2018 Seeger-Zybok RK, Leary EB, Kushida CA, Mignot E. 1050 Patient Engagement for Sleep Research Sleep. 41. DOI: 10.1093/Sleep/Zsy061.1049  0.449
2017 Ruoff C, Pizza F, Trotti LM, Sonka K, Vandi S, Cheung J, Pinto S, Einen M, Simakajornboon N, Han F, Peppard P, Nevsimalova S, Plazzi G, Rye D, Mignot E. The MSLT is Repeatable in Narcolepsy Type 1 But Not Narcolepsy Type 2: A Retrospective Patient Study. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. PMID 29198301 DOI: 10.5664/Jcsm.6882  0.443
2017 Koch H, Schneider LD, Finn LA, Leary EB, Peppard PE, Hagen E, Sorensen HBD, Jennum P, Mignot E. Breathing disturbances without hypoxia are associated with objective sleepiness in sleep apnea. Sleep. PMID 29029253 DOI: 10.1093/Sleep/Zsx152  0.466
2017 Ju YS, Ooms SJ, Sutphen C, Macauley SL, Zangrilli MA, Jerome G, Fagan AM, Mignot E, Zempel JM, Claassen JAHR, Holtzman DM. Slow wave sleep disruption increases cerebrospinal fluid amyloid-β levels. Brain : a Journal of Neurology. 140: 2104-2111. PMID 28899014 DOI: 10.1093/Brain/Awx148  0.44
2017 Olsen AV, Stephansen J, Leary E, Peppard PE, Sheungshul H, Jenum P, Sorensen H, Mignot E. Diagnostic value of sleep stage dissociation as visualized on a 2-Dimensional sleep state space in human narcolepsy. Journal of Neuroscience Methods. PMID 28219726 DOI: 10.1016/J.Jneumeth.2017.02.004  0.472
2017 Simakajornboon N, Melendres C, Sheldon S, Super E, Naqvi K, Brockbank J, Beckerman R, Amin R, Lew J, Malow B, Marcus C, Mason A, Chervin R, Kheirandish-Gozal L, Mignot E. 0947 CLINICAL CHARACTERISTICS OF CHILDHOOD NARCOLEPSY FOLLOWING THE H1N1 PANDEMICS: PRELIMINARY DATA FROM THE PEDIATRIC WORKING GROUP OF THE SLEEP RESEARCH NETWORK Sleep. 40: A352-A352. DOI: 10.1093/Sleepj/Zsx050.946  0.387
2017 Simakajornboon N, Rosen C, Maski K, Perry G, Hassan F, Owens J, Robinson A, Brooks L, Kheirandish-Gozal L, Chen M, Halbower A, Jambhekar S, Graw-Panzer K, Kotagal S, Mignot E. 0907 Increased Cases Of Childhood Narcolepsy After The 2009 H1N1 Pandemics: Preliminary Data From The Pediatric Working Group Of The Sleep Research Network Sleep. 40. DOI: 10.1093/Sleepj/Zsx050.906  0.391
2017 Cheung J, Zeitzer J, Leary E, Mignot E. 0778 VALIDATION OF MINUTE-TO-MINUTE SCORING FOR SLEEP AND WAKE PERIODS IN A CONSUMER WEARABLE DEVICE Sleep. 40: A288-A288. DOI: 10.1093/Sleepj/Zsx050.777  0.641
2017 Schneider L, Koch H, Finn L, Leary E, Peppard P, Hagen E, Sorensen H, Jennum P, Mignot E. 0505 SLEEP APNEA BREATHING DISTURBANCES ARE ASSOCIATED WITH OBJECTIVE SLEEPINESS INDEPENDENT OF HYPOXIA Sleep. 40: A188-A188. DOI: 10.1093/Sleepj/Zsx050.504  0.459
2017 Leary E, Joergensen S, Malunjkar S, Kim S, Mignot E, Barwick F. 0332 Validation Of The Alliance Sleep Questionnaire (Asq) Insomnia Module In Sleep Disordered Patients Sleep. 40. DOI: 10.1093/Sleepj/Zsx050.331  0.478
2017 Takenoshita S, Sakai N, Lin L, Einen M, Leary E, Mignot E, Nishino S. 0322 PLASMA AMINO ACID CHANGES IN PATIENTS WITH INSOMNIA AND SLEEP DISORDERS BREATHING Sleep. 40: A119-A119. DOI: 10.1093/Sleepj/Zsx050.321  0.41
2017 Leary E, Joergensen S, Malunjkar S, Barwick F, Mignot E. 0317 Comparison Of Two Validation Techniques Using The Alliance Sleep Questionnaire (Asq) Insomnia Module Sleep. 40. DOI: 10.1093/Sleepj/Zsx050.316  0.445
2016 McConnell MV, Shcherbina A, Pavlovic A, Homburger JR, Goldfeder RL, Waggot D, Cho MK, Rosenberger ME, Haskell WL, Myers J, Champagne MA, Mignot E, Landray M, Tarassenko L, Harrington RA, et al. Feasibility of Obtaining Measures of Lifestyle From a Smartphone App: The MyHeart Counts Cardiovascular Health Study. Jama Cardiology. PMID 27973671 DOI: 10.1001/Jamacardio.2016.4395  0.329
2016 Plante DT, Finn LA, Hagen EW, Mignot E, Peppard PE. Longitudinal associations of hypersomnolence and depression in the Wisconsin Sleep Cohort Study. Journal of Affective Disorders. 207: 197-202. PMID 27723544 DOI: 10.1016/J.Jad.2016.08.039  0.422
2016 Blackman A, Foster GD, Zammit G, Rosenberg R, Aronne L, Wadden T, Claudius B, Jensen CB, Mignot E. Effect of liraglutide 3.0 mg in individuals with obesity and moderate or severe obstructive sleep apnea: the SCALE Sleep Apnea randomized clinical trial. International Journal of Obesity (2005). PMID 27005405 DOI: 10.1038/Ijo.2016.52  0.442
2016 Gavrilov YV, Ellison BA, Yamamoto M, Reddy H, Haybaeck J, Mignot E, Baumann CR, Scammell TE, Valko PO. Disrupted Sleep in Narcolepsy: Exploring the Integrity of Galanin Neurons in the Ventrolateral Preoptic Area. Sleep. PMID 26951397 DOI: 10.5665/Sleep.5754  0.437
2016 Plante DT, Finn LA, Hagen EW, Mignot E, Peppard PE. Subjective and objective measures of hypersomnolence demonstrate divergent associations with depression among participants in the Wisconsin sleep cohort study Journal of Clinical Sleep Medicine. 12: 571-578. DOI: 10.5664/jcsm.5694  0.353
2015 Plante DT, Finn LA, Hagen EW, Mignot E, Peppard PE. Subjective and Objective Measures of Hypersomnolence Demonstrate Divergent Associations with Depression Among Participants in the Wisconsin Sleep Cohort Study. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. PMID 26888592 DOI: 10.5664/Jcsm.5694  0.442
2015 Christensen JA, Munk EG, Peppard PE, Young T, Mignot E, Sorensen HB, Jennum P. The diagnostic value of power spectra analysis of the sleep electroencephalography in narcoleptic patients. Sleep Medicine. 16: 1516-27. PMID 26611950 DOI: 10.1016/J.Sleep.2015.09.005  0.482
2015 Li J, Moore H, Lin L, Young T, Finn L, Peppard PE, Mignot E. Association of low ferritin with PLM in the Wisconsin Sleep Cohort. Sleep Medicine. 16: 1413-8. PMID 26498245 DOI: 10.1016/J.Sleep.2015.05.015  0.382
2015 Christensen JA, Carrillo O, Leary EB, Peppard PE, Young T, Sorensen HB, Jennum P, Mignot E. Sleep-stage transitions during polysomnographic recordings as diagnostic features of type 1 narcolepsy. Sleep Medicine. PMID 26299470 DOI: 10.1016/J.Sleep.2015.06.007  0.467
2015 Kornum BR, Rico T, Lin L, Huang YS, Arnulf I, Jennum P, Mignot E. Serum cytokine levels in Kleine-Levin syndrome. Sleep Medicine. PMID 26116465 DOI: 10.1016/J.Sleep.2015.02.540  0.392
2015 Christensen JA, Nikolic M, Warby SC, Koch H, Zoetmulder M, Frandsen R, Moghadam KK, Sorensen HB, Mignot E, Jennum PJ. Sleep spindle alterations in patients with Parkinson's disease. Frontiers in Human Neuroscience. 9: 233. PMID 25983685 DOI: 10.3389/Fnhum.2015.00233  0.347
2015 Pizza F, Vandi S, Iloti M, Franceschini C, Liguori R, Mignot E, Plazzi G. Nocturnal Sleep Dynamics Identify Narcolepsy Type 1. Sleep. PMID 25845690 DOI: 10.5665/Sleep.4908  0.453
2015 Wendt SL, Welinder P, Sorensen HB, Peppard PE, Jennum P, Perona P, Mignot E, Warby SC. Inter-expert and intra-expert reliability in sleep spindle scoring. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 126: 1548-56. PMID 25434753 DOI: 10.1016/J.Clinph.2014.10.158  0.451
2015 Moore HE, Mignot E. SEV – a software toolbox for large scale analysis and visualization of polysomnography data Computer Methods in Biomechanics and Biomedical Engineering. Imaging & Visualization. 3: 123-135. DOI: 10.1080/21681163.2014.891076  0.388
2015 Christensen J, Nikolic M, Warby S, Koch H, Zoetmulder M, Frandsen R, Moghadam K, Sorensen H, Mignot E, Jennum P. Sleep spindle alterations in patients with Parkinson's disease Sleep Medicine. 16. DOI: 10.1016/J.Sleep.2015.02.115  0.439
2015 Blackman A, Foster G, Zammit G, Rosenberg R, Aronne L, Wadden T, Claudius B, Jensen C, Mignot E. Liraglutide 3.0 mg reduces severity of obstructive sleep apnea and body weight in obese individuals with moderate or severe disease: scale sleep apnoea tria Sleep Medicine. 16: S24. DOI: 10.1016/J.Sleep.2015.02.058  0.436
2014 Moore H, Leary E, Lee SY, Carrillo O, Stubbs R, Peppard P, Young T, Widrow B, Mignot E. Design and validation of a periodic leg movement detector. Plos One. 9: e114565. PMID 25489744 DOI: 10.1371/Journal.Pone.0114565  0.467
2014 Gottlieb DJ, Hek K, Chen TH, Watson NF, Eiriksdottir G, Byrne EM, Cornelis M, Warby SC, Bandinelli S, Cherkas L, Evans DS, Grabe HJ, Lahti J, Li M, Lehtimäki T, ... ... Mignot E, et al. Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study. Molecular Psychiatry. PMID 25469926 DOI: 10.1038/Mp.2014.133  0.449
2014 Pizza F, Vandi S, Liguori R, Parchi P, Avoni P, Mignot E, Plazzi G. Primary progressive narcolepsy type 1: the other side of the coin. Neurology. 83: 2189-90. PMID 25355832 DOI: 10.1212/Wnl.0000000000001051  0.464
2014 Moore H, Winkelmann J, Lin L, Finn L, Peppard P, Mignot E. Periodic leg movements during sleep are associated with polymorphisms in BTBD9, TOX3/BC034767, MEIS1, MAP2K5/SKOR1, and PTPRD. Sleep. 37: 1535-42. PMID 25142570 DOI: 10.5665/Sleep.4006  0.413
2014 Goldbart A, Peppard P, Finn L, Ruoff CM, Barnet J, Young T, Mignot E. Narcolepsy and predictors of positive MSLTs in the Wisconsin Sleep Cohort. Sleep. 37: 1043-51. PMID 24882899 DOI: 10.5665/Sleep.3758  0.477
2014 Merikangas KR, Zhang J, Emsellem H, Swanson SA, Vgontzas A, Belouad F, Blank MM, Chen W, Einen M, He JP, Heaton L, Nakamura E, Rooholamini S, Mignot E. The structured diagnostic interview for sleep patterns and disorders: rationale and initial evaluation. Sleep Medicine. 15: 530-5. PMID 24780136 DOI: 10.1016/J.Sleep.2013.10.011  0.439
2014 Moghadam KK, Pizza F, La Morgia C, Franceschini C, Tonon C, Lodi R, Barboni P, Seri M, Ferrari S, Liguori R, Donadio V, Parchi P, Cornelio F, Inzitari D, Mignarri A, ... ... Mignot E, et al. Narcolepsy is a common phenotype in HSAN IE and ADCA-DN. Brain : a Journal of Neurology. 137: 1643-55. PMID 24727570 DOI: 10.1093/Brain/Awu069  0.323
2014 Warby SC, Wendt SL, Welinder P, Munk EG, Carrillo O, Sorensen HB, Jennum P, Peppard PE, Perona P, Mignot E. Sleep-spindle detection: crowdsourcing and evaluating performance of experts, non-experts and automated methods. Nature Methods. 11: 385-92. PMID 24562424 DOI: 10.1038/Nmeth.2855  0.398
2014 Collier A, Blackman A, Foster G, Zammit G, Rosenberg R, Wadden T, Aronne L, Claudius B, Jensen T, Mignot E. S28 Liraglutide 3.0 Mg Reduces Severity Of Obstructive Sleep Apnoea And Body Weight In Obese Individuals With Moderate Or Severe Disease: Scale Sleep Apnoea Trial Thorax. 69: A16-A17. DOI: 10.1136/THORAXJNL-2014-206260.34  0.314
2014 Wendt SL, Warby S, Welinder P, Sørensen HBD, Peppard PE, Mignot E, Jennum P. O36: Sleep spindle scoring: performance of humans versus machines Clinical Neurophysiology. 125. DOI: 10.1016/S1388-2457(14)50141-1  0.397
2014 Kornum BR, Mignot E. Sleep Disorders Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders. 585-611. DOI: 10.1016/B978-0-12-398270-4.00036-7  0.351
2013 Pizza F, Franceschini C, Peltola H, Vandi S, Finotti E, Ingravallo F, Nobili L, Bruni O, Lin L, Edwards MJ, Partinen M, Dauvilliers Y, Mignot E, Bhatia KP, Plazzi G. Clinical and polysomnographic course of childhood narcolepsy with cataplexy. Brain : a Journal of Neurology. 136: 3787-95. PMID 24142146 DOI: 10.1093/Brain/Awt277  0.417
2013 Roth T, Dauvilliers Y, Mignot E, Montplaisir J, Paul J, Swick T, Zee P. Disrupted nighttime sleep in narcolepsy. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 9: 955-65. PMID 23997709 DOI: 10.5664/Jcsm.3004  0.485
2013 Pizza F, Vandi S, Poli F, Moghadam KK, Franceschini C, Bellucci C, Cipolli C, Ingravallo F, Natalini G, Mignot E, Plazzi G. Narcolepsy with cataplexy mimicry: the strange case of two sisters. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 9: 611-2. PMID 23772196 DOI: 10.5664/Jcsm.2764  0.436
2013 Nikodemova M, Finn L, Mignot E, Salzieder N, Peppard PE. Association of sleep disordered breathing and cognitive deficit in APOE ε4 carriers. Sleep. 36: 873-80. PMID 23729930 DOI: 10.5665/Sleep.2714  0.392
2013 Mahlios J, De la Herrán-Arita AK, Mignot E. The autoimmune basis of narcolepsy. Current Opinion in Neurobiology. 23: 767-73. PMID 23725858 DOI: 10.1016/J.Conb.2013.04.013  0.405
2013 Andlauer O, Moore H, Jouhier L, Drake C, Peppard PE, Han F, Hong SC, Poli F, Plazzi G, O'Hara R, Haffen E, Roth T, Young T, Mignot E. Nocturnal rapid eye movement sleep latency for identifying patients with narcolepsy/hypocretin deficiency. Jama Neurology. 70: 891-902. PMID 23649748 DOI: 10.1001/Jamaneurol.2013.1589  0.45
2013 Khor SS, Miyagawa T, Toyoda H, Yamasaki M, Kawamura Y, Tanii H, Okazaki Y, Sasaki T, Lin L, Faraco J, Rico T, Honda Y, Honda M, Mignot E, Tokunaga K. Genome-wide association study of HLA-DQB1*06:02 negative essential hypersomnia. Peerj. 1: e66. PMID 23646285 DOI: 10.7717/Peerj.66  0.312
2013 Singh AK, Mahlios J, Mignot E. Genetic association, seasonal infections and autoimmune basis of narcolepsy. Journal of Autoimmunity. 43: 26-31. PMID 23497937 DOI: 10.1016/J.Jaut.2013.02.003  0.423
2013 Pizza F, Moghadam KK, Vandi S, Detto S, Poli F, Mignot E, Ferri R, Plazzi G. Daytime continuous polysomnography predicts MSLT results in hypersomnias of central origin. Journal of Sleep Research. 22: 32-40. PMID 22716477 DOI: 10.1111/J.1365-2869.2012.01032.X  0.481
2012 Pelayo R, Mignot E. The treatment of sleep disorders. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 685-6. PMID 23070732 DOI: 10.1007/S13311-012-0153-6  0.446
2012 Arnulf I, Rico TJ, Mignot E. Diagnosis, disease course, and management of patients with Kleine-Levin syndrome. The Lancet. Neurology. 11: 918-28. PMID 22995695 DOI: 10.1016/S1474-4422(12)70187-4  0.376
2012 Andlauer O, Moore H, Hong SC, Dauvilliers Y, Kanbayashi T, Nishino S, Han F, Silber MH, Rico T, Einen M, Kornum BR, Jennum P, Knudsen S, Nevsimalova S, Poli F, ... ... Mignot E, et al. Predictors of hypocretin (orexin) deficiency in narcolepsy without cataplexy. Sleep. 35: 1247-55F. PMID 22942503 DOI: 10.5665/Sleep.2080  0.462
2012 Weiner Lachmi K, Lin L, Kornum BR, Rico T, Lo B, Aran A, Mignot E. DQB1*06:02 allele-specific expression varies by allelic dosage, not narcolepsy status. Human Immunology. 73: 405-10. PMID 22326585 DOI: 10.1016/J.Humimm.2012.01.004  0.349
2012 Zeitzer JM, Kodama T, Buckmaster CL, Honda Y, Lyons DM, Nishino S, Mignot E. Time-course of cerebrospinal fluid histamine in the wake-consolidated squirrel monkey. Journal of Sleep Research. 21: 189-94. PMID 21910776 DOI: 10.1111/J.1365-2869.2011.00957.X  0.677
2011 Goel N, Banks S, Lin L, Mignot E, Dinges DF. Catechol-O-methyltransferase Val158Met polymorphism associates with individual differences in sleep physiologic responses to chronic sleep loss. Plos One. 6: e29283. PMID 22216231 DOI: 10.1371/Journal.Pone.0029283  0.485
2011 Plazzi G, Pizza F, Palaia V, Franceschini C, Poli F, Moghadam KK, Cortelli P, Nobili L, Bruni O, Dauvilliers Y, Lin L, Edwards MJ, Mignot E, Bhatia KP. Complex movement disorders at disease onset in childhood narcolepsy with cataplexy. Brain : a Journal of Neurology. 134: 3480-92. PMID 21930661 DOI: 10.1093/Brain/Awr244  0.351
2011 Sehgal A, Mignot E. Genetics of sleep and sleep disorders. Cell. 146: 194-207. PMID 21784243 DOI: 10.1016/J.Cell.2011.07.004  0.489
2011 Winkelmann J, Czamara D, Schormair B, Knauf F, Schulte EC, Trenkwalder C, Dauvilliers Y, Polo O, Högl B, Berger K, Fuhs A, Gross N, Stiasny-Kolster K, Oertel W, Bachmann CG, ... ... Mignot E, et al. Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1. Plos Genetics. 7: e1002171. PMID 21779176 DOI: 10.1371/Journal.Pgen.1002171  0.318
2011 Han F, Lin L, Li J, Aran A, Dong SX, An P, Zhao L, Li M, Li QY, Yan H, Wang JS, Gao HY, Li M, Gao ZC, Strohl KP, ... Mignot E, et al. Presentations of primary hypersomnia in Chinese children. Sleep. 34: 627-32. PMID 21532956 DOI: 10.1093/Sleep/34.5.627  0.454
2011 Vardeny O, Peppard PE, Finn LA, Faraco JH, Mignot E, Hla KM. β2 adrenergic receptor polymorphisms and nocturnal blood pressure dipping status in the Wisconsin Sleep Cohort Study. Journal of the American Society of Hypertension : Jash. 5: 114-22. PMID 21414566 DOI: 10.1016/J.Jash.2011.01.005  0.36
2011 Zeitzer JM, Fisicaro RA, Grove ME, Mignot E, Yesavage JA, Friedman L. Faster REM sleep EEG and worse restedness in older insomniacs with HLA DQB1*0602. Psychiatry Research. 187: 397-400. PMID 21292329 DOI: 10.1016/J.Psychres.2011.01.007  0.676
2011 Nishino S, Mignot E. Narcolepsy and cataplexy. Handbook of Clinical Neurology. 99: 783-814. PMID 21056228 DOI: 10.1016/B978-0-444-52007-4.00007-2  0.477
2011 Mignot E, Dauvilliers Y, Montplaisir J. Comment on the letter to the editor by Dr. Marcus on the association between narcolepsy and H1N1 exposure Sleep. 34: 689-690. DOI: 10.5665/Sleep.1024  0.347
2011 Vardeny O, Finn LA, Faraco J, Mignot E, Hla KM, Young T, Peppard PE. ß2 ADRENERGIC RECEPTOR POLYMORPHISMS AND NOCTURNAL BLOOD PRESSURE DIPPING STATUS IN THE WISCONSIN SLEEP COHORT STUDY Journal of the American College of Cardiology. 57. DOI: 10.1016/S0735-1097(11)61296-5  0.41
2011 Faraco J, Mignot E. Genetics of Narcolepsy Sleep Medicine Clinics. 6: 217-228. DOI: 10.1016/J.Jsmc.2011.03.001  0.488
2010 Aran A, Einen M, Lin L, Plazzi G, Nishino S, Mignot E. Clinical and therapeutic aspects of childhood narcolepsy-cataplexy: a retrospective study of 51 children. Sleep. 33: 1457-64. PMID 21102987 DOI: 10.1093/Sleep/33.11.1457  0.376
2010 Goel N, Banks S, Mignot E, Dinges DF. DQB1*0602 predicts interindividual differences in physiologic sleep, sleepiness, and fatigue. Neurology. 75: 1509-19. PMID 20975052 DOI: 10.1212/Wnl.0B013E3181F9615D  0.49
2010 Taheri S, Mignot E. Sleep well and stay slim: dream or reality? Annals of Internal Medicine. 153: 475-6. PMID 20921547 DOI: 10.7326/0003-4819-153-7-201010050-00012  0.468
2010 Appelbaum L, Wang G, Yokogawa T, Skariah GM, Smith SJ, Mourrain P, Mignot E. Circadian and homeostatic regulation of structural synaptic plasticity in hypocretin neurons. Neuron. 68: 87-98. PMID 20920793 DOI: 10.1016/J.Neuron.2010.09.006  0.793
2010 Schwimmer H, Stauss HM, Abboud F, Nishino S, Mignot E, Zeitzer JM. Effects of sleep on the cardiovascular and thermoregulatory systems: a possible role for hypocretins. Journal of Applied Physiology (Bethesda, Md. : 1985). 109: 1053-63. PMID 20705949 DOI: 10.1152/Japplphysiol.00516.2010  0.661
2010 Vetrugno R, D'Angelo R, Moghadam KK, Vandi S, Franceschini C, Mignot E, Montagna P, Plazzi G. Behavioural and neurophysiological correlates of human cataplexy: a video-polygraphic study. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 121: 153-62. PMID 19955018 DOI: 10.1016/J.Clinph.2009.10.012  0.308
2010 Lammers GJ, Bassetti C, Billiard M, Black J, Broughton R, Dauvilliers Y, Ferini Strambi L, Garcia-Borreguero D, Goswami M, Högl B, Iranzo A, Jennum P, Khatami R, Lecendreux M, Mayer G, ... Mignot E, et al. Sodium oxybate is an effective and safe treatment for narcolepsy. Sleep Medicine. 11: 105-6; author reply . PMID 19846338 DOI: 10.1016/J.Sleep.2009.08.003  0.486
2010 Faraco J, Mignot E. Genetics of Sleep and Sleep Disorders in Humans Principles and Practice of Sleep Medicine: Fifth Edition. 184-198. DOI: 10.1016/B978-1-4160-6645-3.00016-5  0.373
2009 Appelbaum L, Wang GX, Maro GS, Mori R, Tovin A, Marin W, Yokogawa T, Kawakami K, Smith SJ, Gothilf Y, Mignot E, Mourrain P. Sleep-wake regulation and hypocretin-melatonin interaction in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 106: 21942-7. PMID 19966231 DOI: 10.1073/Pnas.906637106  0.822
2009 Poli F, Plazzi G, Di Dalmazi G, Ribichini D, Vicennati V, Pizza F, Mignot E, Montagna P, Pasquali R, Pagotto U. Body mass index-independent metabolic alterations in narcolepsy with cataplexy. Sleep. 32: 1491-7. PMID 19928388 DOI: 10.1093/Sleep/32.11.1491  0.363
2009 Mignot E, Huguenard JR. Resting our cortices by going DOWN to sleep. Neuron. 63: 719-21. PMID 19778500 DOI: 10.1016/J.Neuron.2009.09.008  0.451
2009 Zeitzer JM, Buckmaster CL, Landolt HP, Lyons DM, Mignot E. Modafinil and γ-hydroxybutyrate have sleep state-specific pharmacological actions on hypocretin-1 physiology in a primate model of human sleep. Behavioural Pharmacology. 20: 643-52. PMID 19752724 DOI: 10.1097/Fbp.0B013E328331B9Db  0.68
2009 Aran A, Lin L, Nevsimalova S, Plazzi G, Hong SC, Weiner K, Zeitzer J, Mignot E. Elevated anti-streptococcal antibodies in patients with recent narcolepsy onset. Sleep. 32: 979-83. PMID 19725248 DOI: 10.1093/Sleep/32.8.979  0.568
2009 Goel N, Banks S, Mignot E, Dinges DF. PER3 polymorphism predicts cumulative sleep homeostatic but not neurobehavioral changes to chronic partial sleep deprivation. Plos One. 4: e5874. PMID 19516903 DOI: 10.1371/Journal.Pone.0005874  0.485
2009 Hallmayer J, Faraco J, Lin L, Hesselson S, Winkelmann J, Kawashima M, Mayer G, Plazzi G, Nevsimalova S, Bourgin P, Hong SC, Hong SS, Honda Y, Honda M, Högl B, ... ... Mignot E, et al. Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nature Genetics. 41: 708-11. PMID 19412176 DOI: 10.1038/Ng.372  0.35
2009 Nishino S, Sakurai E, Nevsimalova S, Yoshida Y, Watanabe T, Yanai K, Mignot E. Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls. Sleep. 32: 175-80. PMID 19238804 DOI: 10.1093/Sleep/32.2.175  0.305
2009 Honda M, Eriksson KS, Zhang S, Tanaka S, Lin L, Salehi A, Hesla PE, Maehlen J, Gaus SE, Yanagisawa M, Sakurai T, Taheri S, Tsuchiya K, Honda Y, Mignot E. IGFBP3 colocalizes with and regulates hypocretin (orexin). Plos One. 4: e4254. PMID 19158946 DOI: 10.1371/Journal.Pone.0004254  0.401
2009 Kim SJ, Lyoo IK, Lee Y, Jeong D, Kanai H, Ookubo M, Yoshimura A, Okawa M, Yamada N, Munezawa T, Kaneita Y, Osaki Y, Kanda H, Ohtsu T, Minowa M, ... ... Mignot E, et al. Abstracts for the 6th Congress of Asian Sleep Research Society Sleep and Biological Rhythms. 7. DOI: 10.1111/J.1479-8425.2009.00426.X  0.43
2009 Mignot E. In memoriam of Dr. Yutaka Honda (1929-2009), A Pioneer in Sleep Medicine and Narcolepsy Research Sleep. 32: 1528-1529. DOI: 10.1093/Sleep/32.11.1528  0.451
2008 Miyagawa T, Kawashima M, Nishida N, Ohashi J, Kimura R, Fujimoto A, Shimada M, Morishita S, Shigeta T, Lin L, Hong SC, Faraco J, Shin YK, Jeong JH, Okazaki Y, ... ... Mignot E, et al. Variant between CPT1B and CHKB associated with susceptibility to narcolepsy. Nature Genetics. 40: 1324-8. PMID 18820697 DOI: 10.1038/Ng.231  0.427
2008 Alaez C, Lin L, Flores-A H, Vazquez M, Munguia A, Mignot E, Haro R, Baker H, Gorodezky C. Association of narcolepsy-cataplexy with HLA-DRB1 and DQB1 in Mexican patients: a relationship between HLA and gender is suggested. Bmc Medical Genetics. 9: 79. PMID 18706091 DOI: 10.1186/1471-2350-9-79  0.35
2008 Bourgin P, Zeitzer JM, Mignot E. CSF hypocretin-1 assessment in sleep and neurological disorders. The Lancet. Neurology. 7: 649-62. PMID 18565458 DOI: 10.1016/S1474-4422(08)70140-6  0.651
2008 Reiss AL, Hoeft F, Tenforde AS, Chen W, Mobbs D, Mignot EJ. Anomalous hypothalamic responses to humor in cataplexy. Plos One. 3: e2225. PMID 18493621 DOI: 10.1371/Journal.Pone.0002225  0.317
2008 Mignot E. Why we sleep: the temporal organization of recovery. Plos Biology. 6: e106. PMID 18447584 DOI: 10.1371/Journal.Pbio.0060106  0.455
2008 Arnulf I, Lin L, Gadoth N, File J, Lecendreux M, Franco P, Zeitzer J, Lo B, Faraco JH, Mignot E. Kleine-Levin syndrome: a systematic study of 108 patients. Annals of Neurology. 63: 482-93. PMID 18438947 DOI: 10.1002/Ana.21333  0.592
2008 Colas D, Valletta JS, Takimoto-Kimura R, Nishino S, Fujiki N, Mobley WC, Mignot E. Sleep and EEG features in genetic models of Down syndrome. Neurobiology of Disease. 30: 1-7. PMID 18282758 DOI: 10.1016/J.Nbd.2007.07.014  0.481
2008 Ciafaloni E, Mignot E, Sansone V, Hilbert JE, Lin L, Lin X, Liu LC, Pigeon WR, Perlis ML, Thornton CA. The hypocretin neurotransmission system in myotonic dystrophy type 1. Neurology. 70: 226-30. PMID 18195268 DOI: 10.1212/01.Wnl.0000296827.20167.98  0.474
2008 Mishima K, Fujiki N, Yoshida Y, Sakurai T, Honda M, Mignot E, Nishino S. Hypocretin Receptor Expression in Canine and Murine Narcolepsy Models and in Hypocretin-Ligand Deficient Human Narcolepsy Sleep. 31: 1119-1126. DOI: 10.5665/Sleep/31.8.1119  0.405
2007 Yokogawa T, Marin W, Faraco J, Pézeron G, Appelbaum L, Zhang J, Rosa F, Mourrain P, Mignot E. Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants. Plos Biology. 5: e277. PMID 17941721 DOI: 10.1371/Journal.Pbio.0050277  0.826
2007 Appelbaum L, Skariah G, Mourrain P, Mignot E. Comparative expression of p2x receptors and ecto-nucleoside triphosphate diphosphohydrolase 3 in hypocretin and sensory neurons in zebrafish. Brain Research. 1174: 66-75. PMID 17868657 DOI: 10.1016/J.Brainres.2007.06.103  0.352
2007 Szklo-Coxe M, Young T, Finn L, Mignot E. Depression: relationships to sleep paralysis and other sleep disturbances in a community sample. Journal of Sleep Research. 16: 297-312. PMID 17716279 DOI: 10.1111/J.1365-2869.2007.00600.X  0.395
2007 Taheri S, Austin D, Lin L, Nieto FJ, Young T, Mignot E. Correlates of serum C-reactive protein (CRP)--no association with sleep duration or sleep disordered breathing. Sleep. 30: 991-6. PMID 17702268 DOI: 10.1093/Sleep/30.8.991  0.452
2007 Zeitzer JM, Buckmaster CL, Lyons DM, Mignot E. Increasing length of wakefulness and modulation of hypocretin-1 in the wake-consolidated squirrel monkey. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R1736-42. PMID 17686881 DOI: 10.1152/Ajpregu.00460.2007  0.651
2007 Mignot E. A step forward for restless legs syndrome. Nature Genetics. 39: 938-9. PMID 17660808 DOI: 10.1038/Ng0807-938  0.435
2007 Nevsimalova S, Prihodova I, Kemlink D, Lin L, Mignot E. REM behavior disorder (RBD) can be one of the first symptoms of childhood narcolepsy. Sleep Medicine. 8: 784-6. PMID 17569582 DOI: 10.1016/J.Sleep.2006.11.018  0.469
2007 Patel SR, Larkin EK, Mignot E, Lin L, Redline S. The association of angiotensin converting enzyme (ACE) polymorphisms with sleep apnea and hypertension. Sleep. 30: 531-3. PMID 17520798 DOI: 10.1093/Sleep/30.4.531  0.425
2007 Zhang S, Zeitzer JM, Sakurai T, Nishino S, Mignot E. Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy. The Journal of Physiology. 581: 649-63. PMID 17379635 DOI: 10.1113/Jphysiol.2007.129510  0.657
2007 Taiwo OB, Russell IJ, Mignot E, Lin L, Michalek JE, Haynes W, Xiao Y, Zeitzer JM, Larson AA. Normal cerebrospinal fluid levels of hypocretin-1 (orexin A) in patients with fibromyalgia syndrome. Sleep Medicine. 8: 260-5. PMID 17369087 DOI: 10.1016/J.Sleep.2006.08.015  0.66
2007 Friedman LF, Zeitzer JM, Lin L, Hoff D, Mignot E, Peskind ER, Yesavage JA. In Alzheimer disease, increased wake fragmentation found in those with lower hypocretin-1. Neurology. 68: 793-4. PMID 17339595 DOI: 10.1212/01.Wnl.0000256731.57544.F9  0.649
2007 Dauvilliers Y, Arnulf I, Mignot E. Narcolepsy with cataplexy. Lancet. 369: 499-511. PMID 17292770 DOI: 10.1016/S0140-6736(07)60237-2  0.495
2007 Mignot E, Takahashi JS. A circadian sleep disorder reveals a complex clock. Cell. 128: 22-3. PMID 17218251 DOI: 10.1016/J.Cell.2006.12.024  0.415
2007 Schenck CH, Bassetti CL, Arnulf I, Mignot E. English Translations Of The First Clinical Reports On Narcolepsy And Cataplexy By Westphal And Gélineau In The Late 19th Century, With Commentary Journal of Clinical Sleep Medicine. 3: 301-311. DOI: 10.5664/Jcsm.26804  0.324
2007 Hong S-, Jeong J-, Shin Y-, Yoon J-, Lee S-, Han J-, Mignot E. P0082 HLA Class II studies in Korean narcolepsy patients: Additional predisposing effects of DQB1*0301 and protective effects of DQB1*0601 in trans of DQB1*0602 Sleep Medicine. 8. DOI: 10.1016/S1389-9457(07)70340-4  0.413
2007 Ferri R, Zucconi M, Manconi M, Bruni O, Ferini-Strambi L, Vandi S, Montagna P, Mignot E, Plazzi G. S01.B The analysis of LM activity during sleep in narcolepsy/cataplexy Sleep Medicine. 8. DOI: 10.1016/S1389-9457(07)70030-8  0.436
2007 Mignot E, Zeitzer JM. Neurobiology of narcolepsy and hypersomnia Neurobiology of Disease. 715-722. DOI: 10.1016/B978-012088592-3/50068-2  0.679
2006 Ferri R, Zucconi M, Manconi M, Bruni O, Ferini-Strambi L, Vandi S, Montagna P, Mignot E, Plazzi G. Different periodicity and time structure of leg movements during sleep in narcolepsy/cataplexy and restless legs syndrome. Sleep. 29: 1587-94. PMID 17252889 DOI: 10.1093/Sleep/29.12.1587  0.453
2006 Hong SC, Lin L, Jeong JH, Shin YK, Han JH, Lee JH, Lee SP, Zhang J, Einen M, Mignot E. A study of the diagnostic utility of HLA typing, CSF hypocretin-1 measurements, and MSLT testing for the diagnosis of narcolepsy in 163 Korean patients with unexplained excessive daytime sleepiness. Sleep. 29: 1429-38. PMID 17162989 DOI: 10.1093/Sleep/29.11.1429  0.485
2006 Arnulf I, Lin L, Zhang J, Russell IJ, Ripley B, Einen M, Nevsimalova S, Bassetti C, Bourgin P, Nishino S, Mignot E. CSF versus serum leptin in narcolepsy: is there an effect of hypocretin deficiency? Sleep. 29: 1017-24. PMID 16944669 DOI: 10.1093/Sleep/29.8.1017  0.309
2006 Zeitzer JM, Nishino S, Mignot E. The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions. Trends in Pharmacological Sciences. 27: 368-74. PMID 16766052 DOI: 10.1016/J.Tips.2006.05.006  0.651
2006 Mignot E, Lin L, Finn L, Lopes C, Pluff K, Sundstrom ML, Young T. Correlates of sleep-onset REM periods during the Multiple Sleep Latency Test in community adults. Brain : a Journal of Neurology. 129: 1609-23. PMID 16597649 DOI: 10.1093/Brain/Awl079  0.468
2006 Larkin EK, Patel SR, Redline S, Mignot E, Elston RC, Hallmayer J. Apolipoprotein E and obstructive sleep apnea: evaluating whether a candidate gene explains a linkage peak. Genetic Epidemiology. 30: 101-10. PMID 16374834 DOI: 10.1002/Gepi.20127  0.444
2005 Shepard JW, Buysse DJ, Chesson AL, Dement WC, Goldberg R, Guilleminault C, Harris CD, Iber C, Mignot E, Mitler MM, Moore KE, Phillips BA, Quan SF, Rosenberg RS, Roth T, et al. History of the development of sleep medicine in the United States. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 1: 61-82. PMID 17561617  0.576
2005 Mignot E, Nishino S. Emerging therapies in narcolepsy-cataplexy. Sleep. 28: 754-63. PMID 16477963 DOI: 10.1093/Sleep/28.6.754  0.397
2005 Cizza G, Skarulis M, Mignot E. A link between short sleep and obesity: building the evidence for causation. Sleep. 28: 1217-20. PMID 16295203 DOI: 10.1093/Sleep/28.10.1217  0.403
2005 Arnulf I, Zeitzer JM, File J, Farber N, Mignot E. Kleine-Levin syndrome: a systematic review of 186 cases in the literature. Brain : a Journal of Neurology. 128: 2763-76. PMID 16230322 DOI: 10.1093/Brain/Awh620  0.54
2005 Tachibana N, Taniike M, Okinaga T, Ripley B, Mignot E, Nishino S. Hypersomnolence and increased REM sleep with low cerebrospinal fluid hypocretin level in a patient after removal of craniopharyngioma. Sleep Medicine. 6: 567-9. PMID 16084764 DOI: 10.1016/J.Sleep.2005.04.002  0.491
2005 Baumann CR, Stocker R, Imhof HG, Trentz O, Hersberger M, Mignot E, Bassetti CL. Hypocretin-1 (orexin A) deficiency in acute traumatic brain injury. Neurology. 65: 147-9. PMID 16009905 DOI: 10.1212/01.Wnl.0000167605.02541.F2  0.374
2005 Nevsimalova S, Vankova J, Stepanova I, Seemanova E, Mignot E, Nishino S. Hypocretin deficiency in Prader-Willi syndrome. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 12: 70-2. PMID 15613151 DOI: 10.1111/J.1468-1331.2004.00969.X  0.461
2005 Shepard JW, Buysse DJ, Chesson AL, Dement WC, Goldberg R, Guilleminault C, Harris CD, Iber C, Mignot E, Mitler MM, Moore KE, Phillips BA, Quan SF, Rosenberg RS, Roth T, et al. History of the Development of Sleep Medicine in the United States Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 1: 61-82. DOI: 10.5664/Jcsm.26298  0.476
2005 Chen W, Zeitzer JM, Mignot E. The hypocretins and narcolepsy pathophysiology and diagnosis Hypocretins: Integrators of Physiological Functions. 235-254. DOI: 10.1007/0-387-25446-3_15  0.459
2004 Picchioni D, Mignot EJ, Harsh JR. The month-of-birth pattern in narcolepsy is moderated by cataplexy severity and may be independent of HLA-DQB1*0602. Sleep. 27: 1471-5. PMID 15683136 DOI: 10.1093/Sleep/27.8.1471  0.419
2004 Taheri S, Lin L, Austin D, Young T, Mignot E. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. Plos Medicine. 1: e62. PMID 15602591 DOI: 10.1371/Journal.Pmed.0010062  0.424
2004 Mignot E. A year in review--basic science, narcolepsy, and sleep in neurologic diseases. Sleep. 27: 1209-12. PMID 15532216 DOI: 10.1093/Sleep/27.6.1209  0.424
2004 Desarnaud F, Murillo-Rodriguez E, Lin L, Xu M, Gerashchenko D, Shiromani SN, Nishino S, Mignot E, Shiromani PJ. The diurnal rhythm of hypocretin in young and old F344 rats. Sleep. 27: 851-6. PMID 15453542 DOI: 10.1093/Sleep/27.5.851  0.337
2004 Lin L, Finn L, Zhang J, Young T, Mignot E. Angiotensin-converting enzyme, sleep-disordered breathing, and hypertension. American Journal of Respiratory and Critical Care Medicine. 170: 1349-53. PMID 15447944 DOI: 10.1164/Rccm.200405-616Oc  0.412
2004 Mignot E. An update on the pharmacotherapy of excessive daytime sleepiness and cataplexy. Sleep Medicine Reviews. 8: 333-8. PMID 15336234 DOI: 10.1016/J.Smrv.2004.06.003  0.371
2004 Gottlieb DJ, DeStefano AL, Foley DJ, Mignot E, Redline S, Givelber RJ, Young T. APOE epsilon4 is associated with obstructive sleep apnea/hypopnea: the Sleep Heart Health Study. Neurology. 63: 664-8. PMID 15326239 DOI: 10.1212/01.Wnl.0000134671.99649.32  0.366
2004 Mignot E. Sleep, sleep disorders and hypocretin (orexin). Sleep Medicine. 5: S2-8. PMID 15301991 DOI: 10.1016/S1389-9457(04)90001-9  0.476
2004 Zhang S, Zeitzer JM, Yoshida Y, Wisor JP, Nishino S, Edgar DM, Mignot E. Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 release. Sleep. 27: 619-27. PMID 15282996 DOI: 10.1093/Sleep/27.4.619  0.563
2004 Baumann CR, Dauvilliers Y, Mignot E, Bassetti CL. Normal CSF hypocretin-1 (orexin A) levels in dementia with Lewy bodies associated with excessive daytime sleepiness. European Neurology. 52: 73-6. PMID 15256827 DOI: 10.1159/000079749  0.414
2004 Okun ML, Giese S, Lin L, Einen M, Mignot E, Coussons-Read ME. Exploring the cytokine and endocrine involvement in narcolepsy. Brain, Behavior, and Immunity. 18: 326-32. PMID 15157949 DOI: 10.1016/J.Bbi.2003.11.002  0.423
2004 Zeitzer JM, Buckmaster CL, Lyons DM, Mignot E. Locomotor-dependent and -independent components to hypocretin-1 (orexin A) regulation in sleep-wake consolidating monkeys. The Journal of Physiology. 557: 1045-53. PMID 15107479 DOI: 10.1113/Jphysiol.2004.061606  0.645
2004 Martins PJ, D'Almeida V, Pedrazzoli M, Lin L, Mignot E, Tufik S. Increased hypocretin-1 (orexin-a) levels in cerebrospinal fluid of rats after short-term forced activity. Regulatory Peptides. 117: 155-8. PMID 14749034 DOI: 10.1016/J.Regpep.2003.10.003  0.382
2004 Pedrazzoli M, D'Almeida V, Martins PJ, Machado RB, Ling L, Nishino S, Tufik S, Mignot E. Increased hypocretin-1 levels in cerebrospinal fluid after REM sleep deprivation. Brain Research. 995: 1-6. PMID 14644464 DOI: 10.1016/J.Brainres.2003.09.032  0.48
2004 Fromherz S, Mignot E. Narcolepsy research: past, present, and future perspectives. Archives Italiennes De Biologie. 142: 479-486. DOI: 10.4449/Aib.V142I4.419  0.445
2004 Arnulf I, Mignot E. Sodium oxybate for excessive daytime sleepiness in narcolepsy-cataplexy. Sleep. 27: 1242-1243. DOI: 10.1093/Sleep/27.7.1242  0.344
2004 Bourgin P, Mignot E. Hypocretins, nutrition, normal and pathological sleep Medecine Du Sommeil. 1: 17-24. DOI: 10.1016/S1769-4493(04)70163-6  0.454
2004 Mignot E. Erratum to “Sleep, sleep disorders and hypocretin (orexin)” [Sleep Medicine 5 (Suppl. 1) (2004) S2–S8]☆ Sleep Medicine. 5: 515. DOI: 10.1016/J.Sleep.2004.08.001  0.476
2003 Gerashchenko D, Murillo-Rodriguez E, Lin L, Xu M, Hallett L, Nishino S, Mignot E, Shiromani PJ. Relationship between CSF hypocretin levels and hypocretin neuronal loss. Experimental Neurology. 184: 1010-6. PMID 14769395 DOI: 10.1016/S0014-4886(03)00388-1  0.347
2003 Fujiki N, Yoshida Y, Ripley B, Mignot E, Nishino S. Effects of IV and ICV hypocretin-1 (orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin-ligand-deficient narcoleptic dog. Sleep. 26: 953-9. PMID 14746374 DOI: 10.1093/Sleep/26.8.953  0.343
2003 Hecht M, Lin L, Kushida CA, Umetsu DT, Taheri S, Einen M, Mignot E. Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy. Sleep. 26: 809-10. PMID 14655912 DOI: 10.1093/Sleep/26.7.809  0.404
2003 Bassetti C, Gugger M, Bischof M, Mathis J, Sturzenegger C, Werth E, Radanov B, Ripley B, Nishino S, Mignot E. The narcoleptic borderland: a multimodal diagnostic approach including cerebrospinal fluid levels of hypocretin-1 (orexin A). Sleep Medicine. 4: 7-12. PMID 14592354 DOI: 10.1016/S1389-9457(02)00191-0  0.442
2003 Dauvilliers Y, Carlander B, Molinari N, Desautels A, Okun M, Tafti M, Montplaisir J, Mignot E, Billiard M. Month of birth as a risk factor for narcolepsy. Sleep. 26: 663-5. PMID 14572117 DOI: 10.1093/Sleep/26.6.663  0.597
2003 Salomon RM, Ripley B, Kennedy JS, Johnson B, Schmidt D, Zeitzer JM, Nishino S, Mignot E. Diurnal variation of cerebrospinal fluid hypocretin-1 (Orexin-A) levels in control and depressed subjects. Biological Psychiatry. 54: 96-104. PMID 12873798 DOI: 10.1016/S0006-3223(02)01740-7  0.551
2003 Vankova J, Stepanova I, Jech R, Elleder M, Ling L, Mignot E, Nishino S, Nevsimalova S. Sleep disturbances and hypocretin deficiency in Niemann-Pick disease type C. Sleep. 26: 427-30. PMID 12841368 DOI: 10.1093/Sleep/26.4.427  0.496
2003 Martínez-Rodríguez JE, Lin L, Iranzo A, Genis D, Martí MJ, Santamaria J, Mignot E. Decreased hypocretin-1 (Orexin-A) levels in the cerebrospinal fluid of patients with myotonic dystrophy and excessive daytime sleepiness. Sleep. 26: 287-90. PMID 12749547 DOI: 10.1093/Sleep/26.3.287  0.494
2003 Zeitzer JM, Buckmaster CL, Parker KJ, Hauck CM, Lyons DM, Mignot E. Circadian and homeostatic regulation of hypocretin in a primate model: implications for the consolidation of wakefulness. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3555-60. PMID 12716965 DOI: 10.1523/Jneurosci.23-08-03555.2003  0.655
2003 Overeem S, Steens SCA, Good CD, Ferrari MD, Mignot E, Frackowiak RSJ, Buchem MAv, Lammers GJ. Voxel-based morphometry in hypocretin-deficient narcolepsy. Sleep. 26: 44-46. DOI: 10.1093/Sleep/26.1.44  0.326
2003 Mignot E. Narcolepsy, sleep and hypocretin (orexin) Experimental and Clinical Endocrinology & Diabetes. 111. DOI: 10.1055/s-2003-817534  0.373
2002 Taheri S, Mignot E. The genetics of sleep disorders. The Lancet. Neurology. 1: 242-50. PMID 12849457 DOI: 10.1016/S1474-4422(02)00103-5  0.459
2002 Lin L, Wisor J, Shiba T, Taheri S, Yanai K, Wurts S, Lin X, Vitaterna M, Takahashi J, Lovenberg TW, Koehl M, Uhl G, Nishino S, Mignot E. Measurement of hypocretin/orexin content in the mouse brain using an enzyme immunoassay: the effect of circadian time, age and genetic background. Peptides. 23: 2203-11. PMID 12535700 DOI: 10.1016/S0196-9781(02)00251-6  0.346
2002 Pedrazzoli M, Ling L, Young TB, Finn L, Tufik S, Mignot E. Effect of the prion 129 polymorphism on nocturnal sleep and insomnia complaints: a population-based study. Journal of Sleep Research. 11: 357-8. PMID 12464104 DOI: 10.1046/J.1365-2869.2002.00318.X  0.45
2002 Voderholzer U, Riemann D, Gann H, Hornyak M, Juengling F, Schumacher M, Reincke M, Von Herbay A, Nishino S, Mignot E, Berger M, Lieb K. Transient total sleep loss in cerebral Whipple's disease: a longitudinal study. Journal of Sleep Research. 11: 321-9. PMID 12464100 DOI: 10.1046/J.1365-2869.2002.00311.X  0.473
2002 Mignot E, Taheri S, Nishino S. Sleeping with the hypothalamus: emerging therapeutic targets for sleep disorders. Nature Neuroscience. 5: 1071-5. PMID 12403989 DOI: 10.1038/Nn944  0.482
2002 Mignot E, Lammers GJ, Ripley B, Okun M, Nevsimalova S, Overeem S, Vankova J, Black J, Harsh J, Bassetti C, Schrader H, Nishino S. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Archives of Neurology. 59: 1553-62. PMID 12374492 DOI: 10.1001/Archneur.59.10.1553  0.473
2002 Allen RP, Mignot E, Ripley B, Nishino S, Earley CJ. Increased CSF hypocretin-1 (orexin-A) in restless legs syndrome. Neurology. 59: 639-41. PMID 12196669 DOI: 10.1212/Wnl.59.4.639  0.373
2002 Taheri S, Zeitzer JM, Mignot E. The role of hypocretins (orexins) in sleep regulation and narcolepsy. Annual Review of Neuroscience. 25: 283-313. PMID 12052911 DOI: 10.1146/Annurev.Neuro.25.112701.142826  0.672
2002 Fujiki N, Morris L, Mignot E, Nishino S. Analysis of onset location, laterality and propagation of cataplexy in canine narcolepsy. Psychiatry and Clinical Neurosciences. 56: 275-6. PMID 12047593 DOI: 10.1046/J.1440-1819.2002.00978.X  0.371
2002 Nishino S, Ripley B, Mignot E, Benson KL, Zarcone VP. CSF hypocretin-1 levels in schizophrenics and controls: relationship to sleep architecture. Psychiatry Research. 110: 1-7. PMID 12007588 DOI: 10.1016/S0165-1781(02)00032-X  0.474
2002 Overeem S, van Hilten JJ, Ripley B, Mignot E, Nishino S, Lammers GJ. Normal hypocretin-1 levels in Parkinson's disease patients with excessive daytime sleepiness. Neurology. 58: 498-9. PMID 11839864 DOI: 10.1212/Wnl.58.3.498  0.463
2002 Okun ML, Lin L, Pelin Z, Hong S, Mignot E. Clinical aspects of narcolepsy-cataplexy across ethnic groups. Sleep. 25: 27-35. PMID 11833858 DOI: 10.1093/Sleep/25.1.27  0.386
2002 Hong S, Leen-Kim, Park S, Han J, Lee S, Lin L, Okun M, Nishino S, Mignot E. HLA and hypocretin studies in Korean patients with narcolepsy. Sleep. 25: 440-444. DOI: 10.1093/Sleep/25.4.432  0.337
2001 Hartwig G, Harsh J, Ripley B, Nishino S, Mignot E. Low cerebrospinal fluid hypocretin levels found in familial narcolepsy. Sleep Medicine. 2: 451-3. PMID 14592396 DOI: 10.1016/S1389-9457(01)00077-6  0.329
2001 Yoshida Y, Fujiki N, Nakajima T, Ripley B, Matsumura H, Yoneda H, Mignot E, Nishino S. Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities. The European Journal of Neuroscience. 14: 1075-81. PMID 11683899 DOI: 10.1046/J.0953-816X.2001.01725.X  0.478
2001 Mignot E. A commentary on the neurobiology of the hypocretin/orexin system. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: S5-13. PMID 11682267 DOI: 10.1016/S0893-133X(01)00316-5  0.486
2001 Nishino S, Fujiki N, Ripley B, Sakurai E, Kato M, Watanabe T, Mignot E, Yanai K. Decreased brain histamine content in hypocretin/orexin receptor-2 mutated narcoleptic dogs. Neuroscience Letters. 313: 125-8. PMID 11682143 DOI: 10.1016/S0304-3940(01)02270-4  0.362
2001 Overeem S, Mignot E, van Dijk JG, Lammers GJ. Narcolepsy: clinical features, new pathophysiologic insights, and future perspectives. Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society. 18: 78-105. PMID 11435802 DOI: 10.1097/00004691-200103000-00002  0.401
2001 Okura M, Fujiki N, Ripley B, Takahashi S, Amitai N, Mignot E, Nishino S. Narcoleptic canines display periodic leg movements during sleep. Psychiatry and Clinical Neurosciences. 55: 243-4. PMID 11422858 DOI: 10.1046/J.1440-1819.2001.00842.X  0.463
2001 Kadotani H, Kadotani T, Young T, Peppard PE, Finn L, Colrain IM, Murphy GM, Mignot E. Association between apolipoprotein E epsilon4 and sleep-disordered breathing in adults. Jama. 285: 2888-90. PMID 11401610 DOI: 10.1001/Jama.285.22.2888  0.474
2001 Hungs M, Mignot E. Hypocretin/orexin, sleep and narcolepsy. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 23: 397-408. PMID 11340621 DOI: 10.1002/Bies.1058  0.49
2001 Fujiki N, Yoshida Y, Ripley B, Honda K, Mignot E, Nishino S. Changes in CSF hypocretin-1 (orexin A) levels in rats across 24 hours and in response to food deprivation. Neuroreport. 12: 993-7. PMID 11303775 DOI: 10.1097/00001756-200104170-00026  0.315
2001 Mignot E, Lin L, Rogers W, Honda Y, Qiu X, Lin X, Okun M, Hohjoh H, Miki T, Hsu S, Leffell M, Grumet F, Fernandez-Vina M, Honda M, Risch N. Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. American Journal of Human Genetics. 68: 686-99. PMID 11179016 DOI: 10.1086/318799  0.312
2001 Mignot E. A hundred years of narcolepsy research. Archives Italiennes De Biologie. 139: 207-220. DOI: 10.4449/Aib.V139I3.500  0.376
2001 Wisor JP, Nishino S, Sora I, Uhl GH, Mignot E, Edgar DM. Dopaminergic role in stimulant-induced wakefulness. The Journal of Neuroscience. 21: 1787-1794. DOI: 10.1523/Jneurosci.21-05-01787.2001  0.402
2000 Nishino S, Okura M, Mignot E. Narcolepsy: genetic predisposition and neuropharmacological mechanisms. REVIEW ARTICLE. Sleep Medicine Reviews. 4: 57-99. PMID 12531161 DOI: 10.1053/Smrv.1999.0069  0.493
2000 Nishino S, Riehl J, Hong J, Kwan M, Reid M, Mignot E. Is narcolepsy a REM sleep disorder? Analysis of sleep abnormalities in narcoleptic Dobermans. Neuroscience Research. 38: 437-46. PMID 11164570 DOI: 10.1016/S0168-0102(00)00195-4  0.492
2000 Okura M, Riehl J, Mignot E, Nishino S. Sulpiride, a D2/D3 blocker, reduces cataplexy but not REM sleep in canine narcolepsy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 528-38. PMID 11027918 DOI: 10.1016/S0893-133X(00)00140-8  0.462
2000 Kanbayashi T, Honda K, Kodama T, Mignot E, Nishino S. Implication of dopaminergic mechanisms in the wake-promoting effects of amphetamine: a study of D- and L-derivatives in canine narcolepsy. Neuroscience. 99: 651-9. PMID 10974428 DOI: 10.1016/S0306-4522(00)00239-6  0.333
2000 Riehl J, Honda K, Kwan M, Hong J, Mignot E, Nishino S. Chronic oral administration of CG-3703, a thyrotropin releasing hormone analog, increases wake and decreases cataplexy in canine narcolepsy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 34-45. PMID 10869884 DOI: 10.1016/S0893-133X(99)00159-1  0.404
2000 Hong SC, Hayduk R, Lim J, Mignot E. Clinical and polysomnographic features in DQB1*0602 positive and negative narcolepsy patients: results from the modafinil clinical trial. Sleep Medicine. 1: 33-39. PMID 10733618 DOI: 10.1016/S1389-9457(99)00007-6  0.489
2000 Mignot E. 182. Narcolepsy and hypocretins (orexins) Biological Psychiatry. 47. DOI: 10.1016/S0006-3223(00)00853-2  0.377
2000 Hungs M, Mignot E. Pathophysiological and clinical aspects of narcolepsy: a disorder associated with hypocretin abnormalities Somnologie - Schlafforschung Und Schlafmedizin. 4: 111-116. DOI: 10.1007/S11818-000-0002-4  0.494
1999 Honda K, Riehl J, Mignot E, Nishino S. Dopamine D3 agonists into the substantia nigra aggravate cataplexy but do not modify sleep. Neuroreport. 10: 3717-24. PMID 10619672 DOI: 10.1097/00001756-199911260-00046  0.405
1999 Nishino S, Mignot E. Drug treatment of patients with insomnia and excessive daytime sleepiness: pharmacokinetic considerations. Clinical Pharmacokinetics. 37: 305-30. PMID 10554047 DOI: 10.2165/00003088-199937040-00003  0.373
1999 Lin L, Faraco J, Li R, Kadotani H, Rogers W, Lin X, Qiu X, de Jong PJ, Nishino S, Mignot E. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell. 98: 365-76. PMID 10458611 DOI: 10.1016/S0092-8674(00)81965-0  0.483
1999 Katzenberg D, Young T, Lin L, Finn L, Mignot E. A human period gene (HPER1) polymorphism is not associated with diurnal preference in normal adults. Psychiatric Genetics. 9: 107-9. PMID 10412192 DOI: 10.1097/00041444-199906000-00011  0.332
1999 Wu MF, Gulyani SA, Yau E, Mignot E, Phan B, Siegel JM. Locus coeruleus neurons: cessation of activity during cataplexy. Neuroscience. 91: 1389-99. PMID 10391445 DOI: 10.1016/S0306-4522(98)00600-9  0.406
1999 Faraco J, Lin X, Li R, Hinton L, Lin L, Mignot E. Genetic studies in narcolepsy, a disorder affecting REM sleep. The Journal of Heredity. 90: 129-32. PMID 9987919 DOI: 10.1093/Jhered/90.1.129  0.454
1999 Mignot E, Young T, Lin L, Finn L. Nocturnal sleep and daytime sleepiness in normal subjects with HLA-DQB1*0602. Sleep. 22: 347-352. DOI: 10.1093/Sleep/22.3.347  0.497
1999 Anic-Labat S, Guilleminault C, Kraemer HC, Meehan J, Arrigoni J, Mignot E. Validation of a Cataplexy Questionnaire in 983 Sleep-disorders Patients Sleep. 22: 77-87. DOI: 10.1093/Sleep/22.1.77  0.372
1998 Nishino S, Honda K, Riehl J, Okura M, Mignot E. Neuronal activity in the cholinoceptive basal forebrain of freely moving narcoleptic dobermans. Neuroreport. 9: 3653-61. PMID 9858375 DOI: 10.1097/00001756-199811160-00017  0.409
1998 Katzenberg D, Young T, Finn L, Lin L, King DP, Takahashi JS, Mignot E. A CLOCK polymorphism associated with human diurnal preference. Sleep. 21: 569-76. PMID 9779516 DOI: 10.1093/Sleep/21.6.569  0.329
1998 Riehl J, Nishino S, Cederberg R, Dement WC, Mignot E. Development of cataplexy in genetically narcoleptic Dobermans. Experimental Neurology. 152: 292-302. PMID 9710528 DOI: 10.1006/Exnr.1998.6847  0.538
1998 Nishino S, Mignot E, Benson KL, Zarcone VP. Cerebrospinal fluid prostaglandins and corticotropin releasing factor in schizophrenics and controls: relationship to sleep architecture. Psychiatry Research. 78: 141-50. PMID 9657418 DOI: 10.1016/S0165-1781(98)00012-2  0.473
1998 Reid MS, Nishino S, Tafti M, Siegel JM, Dement WC, Mignot E. Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines. Experimental Neurology. 151: 89-104. PMID 9582257 DOI: 10.1006/Exnr.1998.6787  0.607
1998 Kadotani H, Faraco J, Mignot E. Genetic studies in the sleep disorder narcolepsy. Genome Research. 8: 427-34. PMID 9582188 DOI: 10.1101/Gr.8.5.427  0.479
1998 Mignot E. Genetic and familial aspects of narcolepsy. Neurology. 50: S16-22. PMID 9484418 DOI: 10.1212/Wnl.50.2_Suppl_1.S16  0.405
1998 Guilleminault C, Heinzer R, Mignot E, Black J. Investigations into the neurologic basis of narcolepsy. Neurology. 50: S8-15. PMID 9484417 DOI: 10.1212/Wnl.50.2_Suppl_1.S8  0.342
1998 Cederberg R, Nishino S, Dement WC, Mignot E. Breeding history of the Stanford colony of narcoleptic dogs. The Veterinary Record. 142: 31-6. PMID 9481825 DOI: 10.1136/Vr.142.2.31  0.523
1998 Nishino S, Mignot E. Neurobiology of Narcolepsy The Neuroscientist. 4: 133-143. DOI: 10.1177/107385849800400209  0.418
1997 Honda K, Riehl J, Inoué S, Mignot E, Nishino S. Central administration of vitamin B12 aggravates cataplexy in canine narcolepsy. Neuroreport. 8: 3861-5. PMID 9462456 DOI: 10.1097/00001756-199712220-00005  0.406
1997 Mignot E. Genetics of narcolepsy and other sleep disorders. American Journal of Human Genetics. 60: 1289-302. PMID 9199548 DOI: 10.1086/515487  0.445
1997 Rogers AE, Meehan J, Guilleminault C, Grumet FC, Mignot E. HLA DR15 (DR2) and DQB1*0602 typing studies in 188 narcoleptic patients with cataplexy. Neurology. 48: 1550-6. PMID 9191765 DOI: 10.1212/Wnl.48.6.1550  0.444
1997 Nishino S, Mignot E. Pharmacological aspects of human and canine narcolepsy. Progress in Neurobiology. 52: 27-78. PMID 9185233 DOI: 10.1016/S0301-0082(96)00070-6  0.445
1997 Mignot E, Kimura A, Lattermann A, Lin X, Yasunaga S, Mueller-Eckhardt G, Rattazzi C, Lin L, Guilleminault C, Grumet FC, Mayer G, Dement WC, Underhill P. Extensive HLA class II studies in 58 non-DRB1*15 (DR2) narcoleptic patients with cataplexy. Tissue Antigens. 49: 329-41. PMID 9151385 DOI: 10.1111/J.1399-0039.1997.Tb02761.X  0.512
1997 Tafti M, Nishino S, Liao W, Dement WC, Mignot E. Mesopontine organization of cholinergic and catecholaminergic cell groups in the normal and narcoleptic dog. The Journal of Comparative Neurology. 379: 185-97. PMID 9050784 DOI: 10.1002/(Sici)1096-9861(19970310)379:2<185::Aid-Cne2>3.0.Co;2-#  0.642
1997 Nishino S, Arrigoni J, Shelton J, Kanbayashi T, Dement WC, Mignot E. Effects of Thyrotropin-Releasing Hormone and Its Analogs on Daytime Sleepiness and Cataplexy in Canine Narcolepsy The Journal of Neuroscience. 17: 6401-6408. DOI: 10.1523/Jneurosci.17-16-06401.1997  0.467
1997 Mignot E, Hayduk R, Black J, Grumet FC, Guilleminault C. HLA DQB1*0602 is Associated With Cataplexy in 509 Narcoleptic Patients Sleep. 20: 1012-1020. DOI: 10.1093/Sleep/20.11.1012  0.414
1996 Kanbayashi T, Nishino S, Tafti M, Hishikawa Y, Dement WC, Mignot E. Thalidomide, a hypnotic with immune modulating properties, increases cataplexy in canine narcolepsy. Neuroreport. 7: 1881-6. PMID 8905685 DOI: 10.1097/00001756-199608120-00002  0.704
1996 Reid MS, Tafti M, Nishino S, Sampathkumaran R, Siegel JM, Mignot E. Local administration of dopaminergic drugs into the ventral tegmental area modulates cataplexy in the narcoleptic canine. Brain Research. 733: 83-100. PMID 8891251 DOI: 10.1016/0006-8993(96)00541-0  0.512
1996 Kanbayashi T, Nishino S, Tafti M, Hishikawa Y, Dement WC, Mignot E. Thalidomide, immune modulation and narcolepsy. Sleep. 19: 116. PMID 8855033 DOI: 10.1093/Sleep/19.2.116  0.587
1996 Singh SM, George CF, Ott RN, Rattazzi C, Guilleminault C, Dement WC, Mignot E. IgH (mu-switch and gamma-1) region restriction fragment length polymorphism in human narcolepsy. Journal of Clinical Immunology. 16: 208-15. PMID 8840222 DOI: 10.1007/Bf01541226  0.49
1996 Tafti M, Nishino S, Aldrich MS, Liao W, Dement WC, Mignot E. Major histocompatibility class II molecules in the CNS: increased microglial expression at the onset of narcolepsy in canine model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 4588-95. PMID 8764647 DOI: 10.1523/Jneurosci.16-15-04588.1996  0.62
1995 Mignot E, Tafti M, Dement WC, Grumet FC. Narcolepsy and immunity. Advances in Neuroimmunology. 5: 23-37. PMID 7795891 DOI: 10.1016/0960-5428(94)00043-N  0.681
1995 Nishino S, Tafti M, Reid MS, Shelton J, Siegel JM, Dement WC, Mignot E. Muscle atonia is triggered by cholinergic stimulation of the basal forebrain: implication for the pathophysiology of canine narcolepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4806-14. PMID 7623112 DOI: 10.1523/Jneurosci.15-07-04806.1995  0.719
1995 Nitz D, Andersen A, Fahringer H, Nienhuis R, Mignot E, Siegel J. Altered distribution of cholinergic cells in the narcoleptic dog. Neuroreport. 6: 1521-4. PMID 7579139 DOI: 10.1097/00001756-199507310-00014  0.421
1995 Shelton J, Nishino S, Vaught J, Dement WC, Mignot E. Comparative effects of modafinil and amphetamine on daytime sleepiness and cataplexy of narcoleptic dogs. Sleep. 18: 817-826. DOI: 10.1093/Sleep/18.10.817  0.369
1994 Reid MS, Siegel JM, Dement WC, Mignot E. Cholinergic mechanisms in canine narcolepsy--II. Acetylcholine release in the pontine reticular formation is enhanced during cataplexy. Neuroscience. 59: 523-30. PMID 8008206 DOI: 10.1016/0306-4522(94)90174-0  0.536
1994 Reid MS, Tafti M, Geary JN, Nishino S, Siegel JM, Dement WC, Mignot E. Cholinergic mechanisms in canine narcolepsy--I. Modulation of cataplexy via local drug administration into the pontine reticular formation. Neuroscience. 59: 511-22. PMID 8008205 DOI: 10.1016/0306-4522(94)90173-2  0.617
1994 Mignot E, Nishino S, Guilleminault C, Dement WC. Modafinil binds to the dopamine uptake carrier site with low affinity. Sleep. 17: 436-7. PMID 7991954  0.349
1994 Reid MS, Tafti M, Nishino S, Siegel JM, Dement WC, Mignot E. Cholinergic regulation of cataplexy in canine narcolepsy in the pontine reticular formation is mediated by M2 muscarinic receptors. Sleep. 17: 424-35. PMID 7991953 DOI: 10.1093/Sleep/17.5.424  0.62
1994 Gelb M, Guilleminault C, Kraemer H, Lin S, Moon S, Dement WC, Mignot E. Stability of cataplexy over several months--information for the design of therapeutic trials. Sleep. 17: 265-73. PMID 7939127 DOI: 10.1093/Sleep/17.3.265  0.462
1994 Nishino S, Reid MS, Dement WC, Mignot E. Neuropharmacology and neurochemistry of canine narcolepsy. Sleep. 17: S84-92. PMID 7701206 DOI: 10.1093/Sleep/17.Suppl_8.S84  0.589
1994 Mignot E, Bell RA, Rattazzi C, Lovett M, Grumet FC, Dement WC. An immunoglobulin switchlike sequence is linked with canine narcolepsy. Sleep. 17: S68-76. PMID 7701203 DOI: 10.1093/Sleep/17.Suppl_8.S68  0.457
1994 Mignot E, Lin X, Arrigoni J, Macaubas C, Olive F, Hallmayer J, Underhill P, Guilleminault C, Dement WC, Grumet FC. DQB1*0602 and DQA1*0102 (DQ1) are better markers than DR2 for narcolepsy in Caucasian and black Americans. Sleep. 17: S60-7. PMID 7701202 DOI: 10.1093/Sleep/17.Suppl_8.S60  0.476
1994 Guilleminault C, Mignot E, Partinen M. Controversies in the diagnosis of narcolepsy. Sleep. 17: S1-6. PMID 7701189 DOI: 10.1093/Sleep/17.Suppl_8.S1  0.469
1993 Mignot EJ, Dement WC. Narcolepsy in animals and man. Equine Veterinary Journal. 25: 476-7. PMID 8275992  0.368
1993 Mignot E, Lin X, Hesla PE, Dement WC, Guilleminault C, Grumet FC. A novel HLA DR17,DQ1 (DQA1-0102/DQB1-0602 positive) haplotype predisposing to narcolepsy in Caucasians. Sleep. 16: 764-5. PMID 8165393 DOI: 10.1093/SLEEP/16.8.764  0.395
1993 Nishino S, Arrigoni J, Shelton J, Dement WC, Mignot E. Desmethyl metabolites of serotonergic uptake inhibitors are more potent for suppressing canine cataplexy than their parent compounds. Sleep. 16: 706-12. PMID 8165384 DOI: 10.1093/Sleep/16.8.706  0.453
1993 Mignot E, Nishino S, Sharp LH, Arrigoni J, Siegel JM, Reid MS, Edgar DM, Ciaranello RD, Dement WC. Heterozygosity at the canarc-1 locus can confer susceptibility for narcolepsy: induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 1057-64. PMID 8095066 DOI: 10.1523/Jneurosci.13-03-01057.1993  0.606
1993 Mignot E, Renaud A, Nishino S, Arrigoni J, Guilleminault C, Dement WC. Canine cataplexy is preferentially controlled by adrenergic mechanisms: evidence using monoamine selective uptake inhibitors and release enhancers. Psychopharmacology. 113: 76-82. PMID 7862832 DOI: 10.1007/Bf02244337  0.512
1992 Nishino S, Arrigoni J, Sharp LH, Shelton JD, Dement WC, Mignot E. Serum prolactin response to a D2 antagonist in narcoleptic and control canines. Sleep. 15: 474-5. PMID 1455131 DOI: 10.1093/Sleep/15.5.474  0.438
1992 Mignot E, Lin X, Kalil J, George C, Singh S, Billiard M, Montplaisir J, Arrigoni J, Guilleminault C, Dement WC. DQB1-0602 (DQw1) is not present in most nonDR2 Caucasian narcoleptics. Sleep. 15: 415-22. PMID 1455124 DOI: 10.1093/SLEEP/15.5.415  0.478
1992 Valtier D, Dement WC, Mignot E. Monoaminergic uptake in synaptosomes prepared from frozen brain tissue samples of normal and narcoleptic canines. Brain Research. 588: 115-9. PMID 1393561 DOI: 10.1016/0006-8993(92)91350-N  0.451
1992 Matsuki K, Grumet FC, Lin X, Gelb M, Guilleminault C, Dement WC, Mignot E. DQ (rather than DR) gene marks susceptibility to narcolepsy. Lancet (London, England). 339: 1052. PMID 1349071 DOI: 10.1016/0140-6736(92)90571-J  0.452
1992 Siegel J, Nienhuis R, Fahringer H, Chiu C, Dement W, Mignot E, Lufkin R. Activity of medial mesopontine units during cataplexy and sleep-waking states in the narcoleptic dog The Journal of Neuroscience. 12: 1640-1646. DOI: 10.1523/Jneurosci.12-05-01640.1992  0.476
1991 Siegel JM, Nienhuis R, Fahringer HM, Paul R, Shiromani P, Dement WC, Mignot E, Chiu C. Neuronal activity in narcolepsy: identification of cataplexy-related cells in the medial medulla. Science (New York, N.Y.). 252: 1315-8. PMID 1925546 DOI: 10.1126/Science.1925546  0.607
1991 Hawkins M, O'Connor S, Radulovacki M, Bowersox S, Mignot E, Dement W. Radioligand binding to adenosine receptors and adenosine uptake sites in different brain regions of normal and narcoleptic dogs. Pharmacology, Biochemistry, and Behavior. 38: 1-6 3. PMID 1901994 DOI: 10.1016/0091-3057(91)90581-L  0.442
1991 Haak LL, Mignot E, Kilduff TS, Dement WC, Heller HC. Regional changes in central monoamine and metabolite levels during the hibernation cycle in the golden-mantled ground squirrel. Brain Research. 563: 215-20. PMID 1786534 DOI: 10.1016/0006-8993(91)91536-A  0.458
1991 Renaud A, Nishino S, Dement WC, Guilleminault C, Mignot E. Effects of SDZ NVI-085, a putative subtype-selective alpha 1-agonist, on canine cataplexy, a disorder of rapid eye movement sleep. European Journal of Pharmacology. 205: 11-6. PMID 1687464 DOI: 10.1016/0014-2999(91)90763-G  0.532
1991 Mignot E, Wang C, Rattazzi C, Gaiser C, Lovett M, Guilleminault C, Dement WC, Grumet FC. Genetic linkage of autosomal recessive canine narcolepsy with a mu immunoglobulin heavy-chain switch-like segment. Proceedings of the National Academy of Sciences of the United States of America. 88: 3475-8. PMID 1673032 DOI: 10.1073/Pnas.88.8.3475  0.519
1991 Valtier D, Nishino S, Guilleminault C, Dement WC, Mignot E. Platelet alpha 2 adrenoceptors in human and canine narcolepsy. Biological Psychiatry. 29: 376-82. PMID 1645207 DOI: 10.1016/0006-3223(91)90223-9  0.461
1991 Nishino S, Arrigoni J, Valtier D, Miller JD, Guilleminault C, Dement WC, Mignot E. Dopamine D2 mechanisms in canine narcolepsy The Journal of Neuroscience. 11: 2666-2671. DOI: 10.1523/Jneurosci.11-09-02666.1991  0.37
1990 Nishino S, Mignot E, Kilduff TS, Sakai T, Hayaishi O, Dement WC. Prostaglandin E2 levels in cerebrospinal fluid of normal and narcoleptic dogs. Biological Psychiatry. 28: 904-10. PMID 2268692 DOI: 10.1016/0006-3223(90)90570-R  0.559
1989 Nishino S, Mignot E, Fruhstorfer B, Dement WC, Hayaishi O. Prostaglandin E2 and its methyl ester reduce cataplexy in canine narcolepsy. Proceedings of the National Academy of Sciences of the United States of America. 86: 2483-7. PMID 2928344 DOI: 10.1073/Pnas.86.7.2483  0.551
1989 Mignot E, Guilleminault C, Bowersox S, Frusthofer B, Nishino S, Maddaluno J, Ciaranello R, Dement WC. Central alpha 1 adrenoceptor subtypes in narcolepsy-cataplexy: a disorder of REM sleep. Brain Research. 490: 186-91. PMID 2569353 DOI: 10.1016/0006-8993(89)90450-2  0.509
1989 Fruhstorfer B, Mignot E, Bowersox S, Nishino S, Dement WC, Guilleminault C. Canine narcolepsy is associated with an elevated number of alpha 2-receptors in the locus coeruleus. Brain Research. 500: 209-14. PMID 2557958 DOI: 10.1016/0006-8993(89)90315-6  0.46
1989 Mignot E, Bowersox SS, Maddaluno J, Dement W, Ciaranello R. Evidence for multiple [3H]prazosin binding sites in canine brain membranes. Brain Research. 486: 56-66. PMID 2541871 DOI: 10.1016/0006-8993(89)91277-8  0.437
1988 Mignot E, Guilleminault C, Bowersox S, Rappaport A, Dement WC. Role of central alpha-1 adrenoceptors in canine narcolepsy. The Journal of Clinical Investigation. 82: 885-94. PMID 2843574 DOI: 10.1172/Jci113694  0.457
1988 Mignot E, Guilleminault C, Bowersox S, Rappaport A, Dement WC. Effect of alpha 1-adrenoceptors blockade with prazosin in canine narcolepsy. Brain Research. 444: 184-8. PMID 2834022 DOI: 10.1016/0006-8993(88)90927-4  0.501
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