Year |
Citation |
Score |
2020 |
Sohrabi M, Floden AM, Manocha GD, Klug MG, Combs CK. IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer's Disease Transgenic Mouse Model. Frontiers in Cellular Neuroscience. 14: 200. PMID 32719587 DOI: 10.3389/Fncel.2020.00200 |
0.346 |
|
2020 |
Schmit T, Ghosh S, Mathur RK, Barnhardt T, Ambigapathy G, Wu M, Combs C, Khan MN. IL-6 Deficiency Exacerbates Allergic Asthma and Abrogates the Protective Effect of Allergic Inflammation against Pathogenesis. Journal of Immunology (Baltimore, Md. : 1950). PMID 32540994 DOI: 10.4049/Jimmunol.1900755 |
0.34 |
|
2020 |
Kaur H, Nagamoto-Combs K, Golovko S, Golovko MY, Klug MG, Combs CK. Probiotics ameliorate intestinal pathophysiology in a mouse model of Alzheimer's disease. Neurobiology of Aging. 92: 114-134. PMID 32417748 DOI: 10.1016/J.Neurobiolaging.2020.04.009 |
0.358 |
|
2019 |
Smith NA, Germundson DL, Combs CK, Vendsel LP, Nagamoto-Combs K. Astrogliosis Associated With Behavioral Abnormality in a Non-anaphylactic Mouse Model of Cow's Milk Allergy. Frontiers in Cellular Neuroscience. 13: 320. PMID 31379506 DOI: 10.3389/Fncel.2019.00320 |
0.317 |
|
2019 |
Manocha GD, Floden AM, Miller NM, Smith AJ, Nagamoto-Combs K, Saito T, Saido TC, Combs CK. Temporal progression of Alzheimer's disease in brains and intestines of transgenic mice. Neurobiology of Aging. 81: 166-176. PMID 31284126 DOI: 10.1016/J.Neurobiolaging.2019.05.025 |
0.344 |
|
2019 |
Nichols MR, St-Pierre MK, Wendeln AC, Makoni NJ, Gouwens LK, Garrad EC, Sohrabi M, Neher JJ, Tremblay ME, Combs CK. Inflammatory Mechanisms in Neurodegeneration. Journal of Neurochemistry. PMID 30702751 DOI: 10.1111/Jnc.14674 |
0.355 |
|
2019 |
Tublin JM, Adelstein JM, Del Monte F, Combs CK, Wold LE. Getting to the Heart of Alzheimer Disease. Circulation Research. 124: 142-149. PMID 30605407 DOI: 10.1161/Circresaha.118.313563 |
0.307 |
|
2018 |
Kulas JA, Franklin W, Smith NA, Manocha GD, Puig KL, Nagamoto-Combs K, Hendrix RD, Taglialatela G, Barger SW, Combs CK. Ablation of Amyloid Precursor Protein Increases Insulin Degrading Enzyme Levels and Activity in Brain and Peripheral Tissues. American Journal of Physiology. Endocrinology and Metabolism. PMID 30422705 DOI: 10.1152/Ajpendo.00279.2018 |
0.36 |
|
2018 |
Combs C, Manocha G, Ghatak A, Puig K. Anti-α4β1 integrin antibodies attenuated brain inflammatory changes in a mouse model of Alzheimer's disease. Current Alzheimer Research. PMID 30068274 DOI: 10.2174/1567205015666180801111033 |
0.376 |
|
2018 |
Germundson DL, Smith NA, Vendsel LP, Kelsch AV, Combs CK, Nagamoto-Combs K. Oral sensitization to whey proteins induces age- and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food allergy: a potential role of mast cells. Journal of Neuroinflammation. 15: 120. PMID 29685134 DOI: 10.1186/S12974-018-1146-0 |
0.318 |
|
2017 |
Colvin BA, Rogers VA, Kulas JA, Ridgway EA, Amtashar FS, Combs CK, Nichols MR. The conformational epitope for a new Aβ42 protofibril-selective antibody partially overlaps with the peptide N-terminal region. Journal of Neurochemistry. PMID 28881033 DOI: 10.1111/Jnc.14211 |
0.354 |
|
2017 |
Kulas J, Puig K, Combs CK. Amyloid precursor protein in pancreatic islets. The Journal of Endocrinology. PMID 28710249 DOI: 10.1530/Joe-17-0122 |
0.368 |
|
2017 |
Manocha GD, Ghatak A, Puig KL, Kraner SD, Norris CM, Combs CK. NFATc2 Modulates Microglial Activation in the AβPP/PS1 Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 28505967 DOI: 10.3233/Jad-151203 |
0.441 |
|
2017 |
Puig KL, Brose SA, Zhou X, Sens MA, Combs GF, Jensen MD, Golovko MY, Combs CK. Amyloid precursor protein modulates macrophage phenotype and diet-dependent weight gain. Scientific Reports. 7: 43725. PMID 28262782 DOI: 10.1038/Srep43725 |
0.394 |
|
2017 |
Manocha GD, Floden AM, Puig KL, Nagamoto-Combs K, Scherzer CR, Combs CK. Defining the contribution of neuroinflammation to Parkinson's disease in humanized immune system mice. Molecular Neurodegeneration. 12: 17. PMID 28196514 DOI: 10.1186/S13024-017-0158-Z |
0.327 |
|
2016 |
Manocha GD, Floden AM, Rausch K, Kulas JA, McGregor BA, Rojanathammanee L, Puig KR, Puig KL, Karki S, Nichols MR, Darland DC, Porter JE, Combs CK. APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8471-86. PMID 27511018 DOI: 10.1523/Jneurosci.4654-15.2016 |
0.43 |
|
2016 |
Puig KL, Kulas JA, Franklin W, Rakoczy SG, Taglialatela G, Brown-Borg HM, Combs CK. The Ames dwarf mutation attenuates Alzheimer's disease phenotype of APP/PS1 mice. Neurobiology of Aging. 40: 22-40. PMID 26973101 DOI: 10.1016/J.Neurobiolaging.2015.12.021 |
0.359 |
|
2015 |
Combs CK. Are GLP-1 receptor agonists useful against traumatic brain injury? Journal of Neurochemistry. PMID 26234912 DOI: 10.1111/Jnc.13224 |
0.352 |
|
2015 |
Manocha GD, Puig KL, Austin SA, Seyb K, Glicksman MA, Combs CK. Characterization of Novel Src Family Kinase Inhibitors to Attenuate Microgliosis. Plos One. 10: e0132604. PMID 26161952 DOI: 10.1371/Journal.Pone.0132604 |
0.417 |
|
2015 |
Bhatt DP, Puig KL, Gorr MW, Wold LE, Combs CK. A pilot study to assess effects of long-term inhalation of airborne particulate matter on early Alzheimer-like changes in the mouse brain. Plos One. 10: e0127102. PMID 25992783 DOI: 10.1371/Journal.Pone.0127102 |
0.396 |
|
2015 |
Rojanathammanee L, Floden AM, Manocha GD, Combs CK. Attenuation of microglial activation in a mouse model of Alzheimer's disease via NFAT inhibition. Journal of Neuroinflammation. 12: 42. PMID 25889879 DOI: 10.1186/S12974-015-0255-2 |
0.416 |
|
2015 |
Puig KL, Manocha GD, Combs CK. Amyloid precursor protein mediated changes in intestinal epithelial phenotype in vitro. Plos One. 10: e0119534. PMID 25742317 DOI: 10.1371/Journal.Pone.0119534 |
0.405 |
|
2015 |
Rebel AA, Urquhart SA, Puig KL, Ghatak A, Brose SA, Golovko MY, Combs CK. Brain changes associated with thromboxane receptor antagonist SQ 29,548 treatment in a mouse model. Journal of Neuroscience Research. 93: 1279-92. PMID 25703023 DOI: 10.1002/Jnr.23578 |
0.331 |
|
2015 |
Puig KL, Lutz BM, Urquhart SA, Rebel AA, Zhou X, Manocha GD, Sens M, Tuteja AK, Foster NL, Combs CK. Overexpression of mutant amyloid-β protein precursor and presenilin 1 modulates enteric nervous system. Journal of Alzheimer's Disease : Jad. 44: 1263-78. PMID 25408221 DOI: 10.3233/Jad-142259 |
0.405 |
|
2014 |
Ghatak A, Combs CK. Iba1 immunoreactivity is enhanced following an antigen retrieval treatment with EDTA, pH 6.0. Methodsx. 1: 269-274. PMID 25485234 DOI: 10.1016/J.Mex.2014.10.007 |
0.306 |
|
2014 |
Nagamoto-Combs K, Kulas J, Combs CK. A novel cell line from spontaneously immortalized murine microglia. Journal of Neuroscience Methods. 233: 187-98. PMID 24975292 DOI: 10.1016/J.Jneumeth.2014.05.021 |
0.327 |
|
2014 |
Xiao Z, Cilz NI, Kurada L, Hu B, Yang C, Wada E, Combs CK, Porter JE, Lesage F, Lei S. Activation of neurotensin receptor 1 facilitates neuronal excitability and spatial learning and memory in the entorhinal cortex: beneficial actions in an Alzheimer's disease model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7027-42. PMID 24828655 DOI: 10.1523/Jneurosci.0408-14.2014 |
0.327 |
|
2013 |
Rojanathammanee L, Puig KL, Combs CK. Pomegranate polyphenols and extract inhibit nuclear factor of activated T-cell activity and microglial activation in vitro and in a transgenic mouse model of Alzheimer disease. The Journal of Nutrition. 143: 597-605. PMID 23468550 DOI: 10.3945/Jn.112.169516 |
0.352 |
|
2013 |
Soliman ML, Combs CK, Rosenberger TA. Modulation of inflammatory cytokines and mitogen-activated protein kinases by acetate in primary astrocytes. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 287-300. PMID 23233245 DOI: 10.1007/S11481-012-9426-4 |
0.451 |
|
2013 |
Puig KL, Combs CK. Expression and function of APP and its metabolites outside the central nervous system. Experimental Gerontology. 48: 608-11. PMID 22846461 DOI: 10.1016/J.Exger.2012.07.009 |
0.363 |
|
2012 |
Combs C, Nichols M. Introduction: roles that intracellular beta amyloid (Aβ) may have during disease. Life Sciences. 91: 1140. PMID 23157940 DOI: 10.1016/J.Lfs.2012.10.005 |
0.349 |
|
2012 |
Soliman ML, Puig KL, Combs CK, Rosenberger TA. Acetate reduces microglia inflammatory signaling in vitro. Journal of Neurochemistry. 123: 555-67. PMID 22924711 DOI: 10.1111/J.1471-4159.2012.07955.X |
0.426 |
|
2012 |
Dhawan G, Combs CK. Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease. Journal of Neuroinflammation. 9: 117. PMID 22673542 DOI: 10.1186/1742-2094-9-117 |
0.415 |
|
2012 |
Puig KL, Floden AM, Adhikari R, Golovko MY, Combs CK. Amyloid precursor protein and proinflammatory changes are regulated in brain and adipose tissue in a murine model of high fat diet-induced obesity. Plos One. 7: e30378. PMID 22276186 DOI: 10.1371/Journal.Pone.0030378 |
0.318 |
|
2012 |
Dhawan G, Floden AM, Combs CK. Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism. Neurobiology of Aging. 33: 2247-61. PMID 22133278 DOI: 10.1016/J.Neurobiolaging.2011.10.027 |
0.419 |
|
2012 |
Puig KL, Swigost AJ, Zhou X, Sens MA, Combs CK. Amyloid precursor protein expression modulates intestine immune phenotype. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 215-30. PMID 22124967 DOI: 10.1007/S11481-011-9327-Y |
0.417 |
|
2011 |
Grisanti LA, Woster AP, Dahlman J, Sauter ER, Combs CK, Porter JE. α1-adrenergic receptors positively regulate Toll-like receptor cytokine production from human monocytes and macrophages. The Journal of Pharmacology and Experimental Therapeutics. 338: 648-57. PMID 21571945 DOI: 10.1124/Jpet.110.178012 |
0.708 |
|
2011 |
Rojanathammanee L, Murphy EJ, Combs CK. Expression of mutant alpha-synuclein modulates microglial phenotype in vitro. Journal of Neuroinflammation. 8: 44. PMID 21554732 DOI: 10.1186/1742-2094-8-44 |
0.319 |
|
2011 |
Floden AM, Combs CK. Microglia demonstrate age-dependent interaction with amyloid-β fibrils. Journal of Alzheimer's Disease : Jad. 25: 279-93. PMID 21403390 DOI: 10.3233/Jad-2011-101014 |
0.383 |
|
2011 |
Austin SA, Rojanathammanee L, Golovko MY, Murphy EJ, Combs CK. Lack of alpha-synuclein modulates microglial phenotype in vitro. Neurochemical Research. 36: 994-1004. PMID 21384098 DOI: 10.1007/S11064-011-0439-9 |
0.402 |
|
2010 |
Nagamoto-Combs K, Combs CK. Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9641-6. PMID 20631193 DOI: 10.1523/Jneurosci.0828-10.2010 |
0.454 |
|
2010 |
Sondag CM, Combs CK. Adhesion of monocytes to type I collagen stimulates an APP-dependent proinflammatory signaling response and release of Abeta1-40. Journal of Neuroinflammation. 7: 22. PMID 20302643 DOI: 10.1186/1742-2094-7-22 |
0.402 |
|
2010 |
Combs CK. Manipulating phagocyte activity in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 20: 441-3. PMID 20182046 DOI: 10.3233/Jad-2010-090896 |
0.401 |
|
2010 |
Grisanti LA, Evanson J, Marchus E, Jorissen H, Woster AP, DeKrey W, Sauter ER, Combs CK, Porter JE. Pro-inflammatory responses in human monocytes are beta1-adrenergic receptor subtype dependent. Molecular Immunology. 47: 1244-54. PMID 20116105 DOI: 10.1016/J.Molimm.2009.12.013 |
0.702 |
|
2010 |
Austin SA, Combs CK. Amyloid precursor protein mediates monocyte adhesion in AD tissue and apoE(-)/(-) mice. Neurobiology of Aging. 31: 1854-66. PMID 19058878 DOI: 10.1016/J.Neurobiolaging.2008.10.013 |
0.383 |
|
2009 |
Austin SA, Sens MA, Combs CK. Amyloid precursor protein mediates a tyrosine kinase-dependent activation response in endothelial cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14451-62. PMID 19923279 DOI: 10.1523/Jneurosci.3107-09.2009 |
0.403 |
|
2009 |
Combs CK. Inflammation and microglia actions in Alzheimer's disease. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 380-8. PMID 19669893 DOI: 10.1007/S11481-009-9165-3 |
0.405 |
|
2009 |
Sondag CM, Dhawan G, Combs CK. Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia. Journal of Neuroinflammation. 6: 1. PMID 19123954 DOI: 10.1186/1742-2094-6-1 |
0.385 |
|
2009 |
Golovko MY, Barceló-Coblijn G, Castagnet PI, Austin S, Combs CK, Murphy EJ. The role of alpha-synuclein in brain lipid metabolism: a downstream impact on brain inflammatory response. Molecular and Cellular Biochemistry. 326: 55-66. PMID 19116775 DOI: 10.1007/S11010-008-0008-Y |
0.313 |
|
2008 |
Combs CK, Floden A, Sondag C. P3-355: Oligomeric beta-amyloid peptide stimulates a unique microglial activation phenotype Alzheimer's & Dementia. 4: T626-T626. DOI: 10.1016/J.Jalz.2008.05.1925 |
0.359 |
|
2007 |
Nagamoto-Combs K, McNeal DW, Morecraft RJ, Combs CK. Prolonged microgliosis in the rhesus monkey central nervous system after traumatic brain injury. Journal of Neurotrauma. 24: 1719-42. PMID 18001202 DOI: 10.1089/Neu.2007.0377 |
0.358 |
|
2007 |
Woster AP, Combs CK. Differential ability of a thiazolidinedione PPARgamma agonist to attenuate cytokine secretion in primary microglia and macrophage-like cells. Journal of Neurochemistry. 103: 67-76. PMID 17573821 DOI: 10.1111/J.1471-4159.2007.04706.X |
0.713 |
|
2007 |
Floden AM, Combs CK. Microglia repetitively isolated from in vitro mixed glial cultures retain their initial phenotype. Journal of Neuroscience Methods. 164: 218-24. PMID 17553568 DOI: 10.1016/J.Jneumeth.2007.04.018 |
0.364 |
|
2007 |
Jara JH, Singh BB, Floden AM, Combs CK. Tumor necrosis factor alpha stimulates NMDA receptor activity in mouse cortical neurons resulting in ERK-dependent death. Journal of Neurochemistry. 100: 1407-20. PMID 17241124 DOI: 10.1111/J.1471-4159.2006.04330.X |
0.701 |
|
2006 |
Austin SA, Floden AM, Murphy EJ, Combs CK. Alpha-synuclein expression modulates microglial activation phenotype. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10558-63. PMID 17035541 DOI: 10.1523/Jneurosci.1799-06.2006 |
0.375 |
|
2006 |
Floden AM, Combs CK. Beta-amyloid stimulates murine postnatal and adult microglia cultures in a unique manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4644-8. PMID 16641245 DOI: 10.1523/Jneurosci.4822-05.2006 |
0.403 |
|
2006 |
Sondag CM, Combs CK. Amyloid precursor protein cross-linking stimulates beta amyloid production and pro-inflammatory cytokine release in monocytic lineage cells. Journal of Neurochemistry. 97: 449-61. PMID 16539666 DOI: 10.1111/J.1471-4159.2006.03759.X |
0.477 |
|
2006 |
Shavali S, Combs CK, Ebadi M. Reactive macrophages increase oxidative stress and alpha-synuclein nitration during death of dopaminergic neuronal cells in co-culture: relevance to Parkinson's disease. Neurochemical Research. 31: 85-94. PMID 16475001 DOI: 10.1007/S11064-005-9233-X |
0.352 |
|
2006 |
Sohrabi M, Combs CK. P1-112: EFFECTS OF DEXTRAN SULFATE SODIUM-INDUCED COLITIS ON A MOUSE MODEL OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P314-P314. DOI: 10.1016/J.Jalz.2018.06.115 |
0.31 |
|
2006 |
Kaur H, Combs CK. P1-019: EFFECT OF PROBIOTIC SUPPLEMENTATION ON BRAIN AND INTESTINAL PATHOLOGY IN A MOUSE MODEL OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P272-P272. DOI: 10.1016/J.Jalz.2018.06.020 |
0.313 |
|
2005 |
Floden AM, Li S, Combs CK. Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2566-75. PMID 15758166 DOI: 10.1523/Jneurosci.4998-04.2005 |
0.458 |
|
2004 |
Sondag CM, Combs CK. Amyloid precursor protein mediates proinflammatory activation of monocytic lineage cells. The Journal of Biological Chemistry. 279: 14456-63. PMID 14732706 DOI: 10.1074/Jbc.M313747200 |
0.478 |
|
2001 |
Combs CK, Bates P, Karlo JC, Landreth GE. Regulation of beta-amyloid stimulated proinflammatory responses by peroxisome proliferator-activated receptor alpha. Neurochemistry International. 39: 449-57. PMID 11578780 DOI: 10.1016/S0197-0186(01)00052-3 |
0.389 |
|
2000 |
Combs CK, Johnson DE, Karlo JC, Cannady SB, Landreth GE. Inflammatory Mechanisms in Alzheimer's Disease: Inhibition of β-Amyloid-Stimulated Proinflammatory Responses and Neurotoxicity by PPARγ Agonists The Journal of Neuroscience. 20: 558-567. DOI: 10.1523/JNEUROSCI.20-02-00558.2000 |
0.317 |
|
2000 |
Combs CK, Karlo JC, Kao S. Neuronal apoptosis mediated via proinflammatory secretions from β-amyloid stimulated monocytes occurs in a TNFα-dependent fashion Neurobiology of Aging. 21: 25. DOI: 10.1016/S0197-4580(00)82788-8 |
0.388 |
|
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