Frank V. Brozovich - Publications

Affiliations: 
Case Western Reserve University School of Medicine, Cleveland, OH, United States 
Area:
Medical Biophysics

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lyle MA, Alabdaljabar MS, Han YS, Brozovich FV. The vasculature in HFpEF vs HFrEF: differences in contractile protein expression produce distinct phenotypes. Heliyon. 6: e03129. PMID 31909283 DOI: 10.1016/j.heliyon.2019.e03129  0.301
2017 Lyle MA, Davis JP, Brozovich FV. Regulation of Pulmonary Vascular Smooth Muscle Contractility in Pulmonary Arterial Hypertension: Implications for Therapy. Frontiers in Physiology. 8: 614. PMID 28878690 DOI: 10.3389/fphys.2017.00614  0.328
2016 Lin S, Brozovich FV. MYPT1 isoforms expressed in HEK293T cells are differentially phosphorylated after GTPγS treatment. Journal of Smooth Muscle Research = Nihon Heikatsukin Gakkai Kikanshi. 52: 66-77. PMID 27725371 DOI: 10.1540/jsmr.52.66  0.352
2013 Konik EA, Han YS, Brozovich FV. The role of pulmonary vascular contractile protein expression in pulmonary arterial hypertension. Journal of Molecular and Cellular Cardiology. 65: 147-55. PMID 24161910 DOI: 10.1016/j.yjmcc.2013.10.009  0.335
2012 Han YS, Brozovich FV. Acute Myocardial Ischemia Alters Vascular Reactivity of Tertiary Mesenteric Arteries Biophysical Journal. 102: 354a. DOI: 10.1016/J.Bpj.2011.11.1937  0.486
2011 Bishu K, Hamdani N, Mohammed SF, Kruger M, Ohtani T, Ogut O, Brozovich FV, Burnett JC, Linke WA, Redfield MM. Sildenafil and B-type natriuretic peptide acutely phosphorylate titin and improve diastolic distensibility in vivo. Circulation. 124: 2882-91. PMID 22144574 DOI: 10.1161/Circulationaha.111.048520  0.322
2011 Yuen S, Ogut O, Brozovich FV. MYPT1 protein isoforms are differentially phosphorylated by protein kinase G. The Journal of Biological Chemistry. 286: 37274-9. PMID 21890627 DOI: 10.1074/Jbc.M111.282905  0.494
2011 Yuen S, Ogut O, Brozovich FV. Differential phosphorylation of LZ+/LZ- MYPT1 isoforms by PKGIα: implication for vascular reactivity Bmc Pharmacology. 11. DOI: 10.1186/1471-2210-11-S1-P78  0.449
2010 Guvenc B, Ustunel C, Ozturk N, Brozovich FV. A dynamic approach reveals non-muscle myosin influences the overall smooth muscle cross-bridge cycling rate. Febs Letters. 584: 2862-6. PMID 20447398 DOI: 10.1016/j.febslet.2010.04.070  0.48
2009 Yuen SL, Ogut O, Brozovich FV. Nonmuscle myosin is regulated during smooth muscle contraction. American Journal of Physiology. Heart and Circulatory Physiology. 297: H191-9. PMID 19429828 DOI: 10.1152/Ajpheart.00132.2009  0.566
2008 Ogut O, Brozovich FV. The potential role of MLC phosphatase and MAPK signalling in the pathogenesis of vascular dysfunction in heart failure. Journal of Cellular and Molecular Medicine. 12: 2158-64. PMID 19120700 DOI: 10.1111/J.1582-4934.2008.00536.X  0.369
2008 Chen FC, Brozovich FV. Gene expression profiles of vascular smooth muscle show differential expression of mitogen-activated protein kinase pathways during captopril therapy of heart failure. Journal of Vascular Research. 45: 445-54. PMID 18418003 DOI: 10.1159/000126735  0.461
2007 Ogut O, Yuen SL, Brozovich FV. Regulation of the smooth muscle contractile phenotype by nonmuscle myosin. Journal of Muscle Research and Cell Motility. 28: 409-14. PMID 18347921 DOI: 10.1007/S10974-008-9132-2  0.593
2007 Given AM, Ogut O, Brozovich FV. MYPT1 mutants demonstrate the importance of aa 888-928 for the interaction with PKGIalpha. American Journal of Physiology. Cell Physiology. 292: C432-9. PMID 16870832 DOI: 10.1152/Ajpcell.00175.2006  0.316
2006 El-Toukhy A, Given AM, Ogut O, Brozovich FV. PHI-1 interacts with the catalytic subunit of myosin light chain phosphatase to produce a Ca(2+) independent increase in MLC(20) phosphorylation and force in avian smooth muscle. Febs Letters. 580: 5779-84. PMID 17022978 DOI: 10.1016/J.Febslet.2006.09.035  0.772
2006 Babu GJ, Celia G, Rhee AY, Yamamura H, Takahashi K, Brozovich FV, Osol G, Periasamy M. Effects of h1-calponin ablation on the contractile properties of bladder versus vascular smooth muscle in mice lacking SM-B myosin. The Journal of Physiology. 577: 1033-42. PMID 16973711 DOI: 10.1113/Jphysiol.2006.118828  0.764
2006 Chen FC, Ogut O, Rhee AY, Hoit BD, Brozovich FV. Captopril prevents myosin light chain phosphatase isoform switching to preserve normal cGMP-mediated vasodilatation. Journal of Molecular and Cellular Cardiology. 41: 488-95. PMID 16815432 DOI: 10.1016/J.Yjmcc.2006.05.018  0.757
2006 Rhee AY, Ogut O, Brozovich FV. Nonmuscle myosin, force maintenance, and the tonic contractile phenotype in smooth muscle. PflüGers Archiv : European Journal of Physiology. 452: 766-74. PMID 16685563 DOI: 10.1007/S00424-006-0091-4  0.794
2005 El-Touhky A, Given AM, Cochard A, Brozovich FV. PHI-1 induced enhancement of myosin phosphorylation in chicken smooth muscle. Febs Letters. 579: 4271-7. PMID 16081075 DOI: 10.1016/J.Febslet.2005.06.059  0.557
2004 Karagiannis P, Babu GJ, Periasamy M, Brozovich FV. Myosin heavy chain isoform expression regulates shortening velocity in smooth muscle: studies using an SMB KO mouse line. Journal of Muscle Research and Cell Motility. 25: 149-58. PMID 15360130 DOI: 10.1023/B:Jure.0000035879.87045.4B  0.8
2004 Karim SM, Rhee AY, Given AM, Faulx MD, Hoit BD, Brozovich FV. Vascular reactivity in heart failure: role of myosin light chain phosphatase. Circulation Research. 95: 612-8. PMID 15321927 DOI: 10.1161/01.Res.0000142736.39359.58  0.775
2004 Huang QQ, Fisher SA, Brozovich FV. Unzipping the role of myosin light chain phosphatase in smooth muscle cell relaxation. The Journal of Biological Chemistry. 279: 597-603. PMID 14530290 DOI: 10.1074/Jbc.M308496200  0.545
2003 Karagiannis P, Brozovich FV. The kinetic properties of smooth muscle: how a little extra weight makes myosin faster. Journal of Muscle Research and Cell Motility. 24: 157-63. PMID 14609027 DOI: 10.1023/A:1026049429858  0.777
2003 Brozovich FV. Rho signaling: agonist stimulation and depolarization come together. Circulation Research. 93: 481-3. PMID 14500329 DOI: 10.1161/01.Res.0000093183.00556.D5  0.505
2003 Ogut O, Brozovich FV. Creatine phosphate consumption and the actomyosin crossbridge cycle in cardiac muscles. Circulation Research. 93: 54-60. PMID 12791710 DOI: 10.1161/01.Res.0000080536.06932.E3  0.533
2003 Ogut O, Brozovich FV. Regulation of force in vascular smooth muscle. Journal of Molecular and Cellular Cardiology. 35: 347-55. PMID 12689814 DOI: 10.1016/S0022-2828(03)00045-2  0.585
2003 Karagiannis P, Babu GJ, Periasamy M, Brozovich FV. The smooth muscle myosin seven amino acid heavy chain insert's kinetic role in the crossbridge cycle for mouse bladder. The Journal of Physiology. 547: 463-73. PMID 12562924 DOI: 10.1113/Jphysiol.2002.035717  0.798
2003 Rhee AY, Brozovich FV. Force maintenance in smooth muscle: analysis using sinusoidal perturbations. Archives of Biochemistry and Biophysics. 410: 25-38. PMID 12559974 DOI: 10.1016/S0003-9861(02)00634-3  0.772
2002 MacFarland SM, Jin JP, Brozovich FV. Troponin T isoforms modulate calcium dependence of the kinetics of the cross-bridge cycle: studies using a transgenic mouse line. Archives of Biochemistry and Biophysics. 405: 241-6. PMID 12220538 DOI: 10.1016/S0003-9861(02)00370-3  0.514
2002 Brozovich FV. Myosin light chain phosphatase: it gets around. Circulation Research. 90: 500-2. PMID 11909811 DOI: 10.1161/01.Res.0000014224.43774.03  0.57
2002 Richards CT, Ogut O, Brozovich FV. Agonist-induced force enhancement: the role of isoforms and phosphorylation of the myosin-targeting subunit of myosin light chain phosphatase. The Journal of Biological Chemistry. 277: 4422-7. PMID 11726673 DOI: 10.1074/Jbc.M111047200  0.471
2001 Khatri JJ, Joyce KM, Brozovich FV, Fisher SA. Role of Myosin Phosphatase Isoforms in cGMP-mediated Smooth Muscle Relaxation Journal of Biological Chemistry. 276: 37250-37257. PMID 11486008 DOI: 10.1074/Jbc.M105275200  0.537
2001 Ogut O, Brozovich FV. Determinants of the contractile properties in the embryonic chicken gizzard and aorta. American Journal of Physiology. Cell Physiology. 279: C1722-32. PMID 11078686 DOI: 10.1152/Ajpcell.2000.279.6.C1722  0.633
2001 Facemire C, Brozovich FV, Jin JP. The maximal velocity of vascular smooth muscle shortening is independent of the expression of calponin. Journal of Muscle Research and Cell Motility. 21: 367-73. PMID 11032347 DOI: 10.1023/A:1005680614296  0.634
2000 Smith PG, Roy C, Fisher S, Huang QQ, Brozovich F. Selected contribution: mechanical strain increases force production and calcium sensitivity in cultured airway smooth muscle cells. Journal of Applied Physiology (Bethesda, Md. : 1985). 89: 2092-8. PMID 11053368 DOI: 10.1152/Jappl.2000.89.5.2092  0.455
2000 Rhee AY, Brozovich FV. The smooth muscle cross-bridge cycle studied using sinusoidal length perturbations. Biophysical Journal. 79: 1511-23. PMID 10969012 DOI: 10.1016/S0006-3495(00)76402-2  0.788
2000 Huang QQ, Fisher SA, Brozovich FV. Forced expression of essential myosin light chain isoforms demonstrates their role in smooth muscle force production. The Journal of Biological Chemistry. 274: 35095-8. PMID 10574990 DOI: 10.1074/Jbc.274.49.35095  0.655
2000 Huang QQ, Brozovich FV, Jin JP. Fast skeletal muscle troponin T increases the cooperativity of transgenic mouse cardiac muscle contraction. The Journal of Physiology. 231-42. PMID 10517814 DOI: 10.1111/J.1469-7793.1999.00231.X  0.574
1999 Smith PG, Roy C, Dreger J, Brozovich F. Mechanical strain increases velocity and extent of shortening in cultured airway smooth muscle cells. The American Journal of Physiology. 277: L343-8. PMID 10444529 DOI: 10.1152/Ajplung.1999.277.2.L343  0.438
1999 Shue GH, Brozovich FV. The frequency response of smooth muscle stiffness during Ca2+-activated contraction. Biophysical Journal. 76: 2361-9. PMID 10233055 DOI: 10.1016/S0006-3495(99)77393-5  0.554
1997 Fisher SA, Ikebe M, Brozovich F. Endothelin-1 alters the contractile phenotype of cultured embryonic smooth muscle cells. Circulation Research. 80: 885-93. PMID 9168792 DOI: 10.1161/01.Res.80.6.885  0.578
1996 Egelhoff TT, Naismith TV, Brozovich FV. Myosin-based cortical tension in Dictyostelium resolved into heavy and light chain-regulated components. Journal of Muscle Research and Cell Motility. 17: 269-74. PMID 8793728 DOI: 10.1007/Bf00124248  0.441
1996 Ikebe M, Brozovich FV. Protein kinase C increases force and slows relaxation in smooth muscle: evidence for regulation of the myosin light chain phosphatase. Biochemical and Biophysical Research Communications. 225: 370-6. PMID 8753771 DOI: 10.1006/Bbrc.1996.1182  0.616
1996 Brozovich FV. Mechanical changes after histamine activation of intact single vascular smooth muscle cells. Archives of Biochemistry and Biophysics. 330: 125-8. PMID 8651686 DOI: 10.1006/ABBI.1996.0233  0.495
1996 Tokui T, Brozovich F, Ando S, Ikebe M. Enhancement of smooth muscle contraction with protein phosphatase inhibitor 1: activation of inhibitor 1 by cGMP-dependent protein kinase. Biochemical and Biophysical Research Communications. 220: 777-83. PMID 8607841 DOI: 10.1006/Bbrc.1996.0480  0.502
1995 Brozovich FV, Yamakawa M. Thin filament regulation of force activation is not essential in single vascular smooth muscle cells. The American Journal of Physiology. 268: C237-42. PMID 7840153 DOI: 10.1152/AJPCELL.1995.268.1.C237  0.554
1995 Brozovich FV. PKC regulates agonist-induced force enhancement in single alpha-toxin-permeabilized vascular smooth muscle cells. The American Journal of Physiology. 268: C1202-6. PMID 7762613 DOI: 10.1152/Ajpcell.1995.268.5.C1202  0.54
1993 Brozovich FV, Yamakawa M. Agonist activation modulates cross-bridge states in single vascular smooth muscle cells. The American Journal of Physiology. 264: C103-8. PMID 8430760 DOI: 10.1152/AJPCELL.1993.264.1.C103  0.465
1990 Brozovich FV, Walsh MP, Morgan KG. Regulation of force in skinned, single cells of ferret aortic smooth muscle PflüGers Archiv European Journal of Physiology. 416: 742-749. PMID 2247345 DOI: 10.1007/Bf00370624  0.44
1989 Brozovich FV, Morgan KG. Stimulus-specific changes in mechanical properties of vascular smooth muscle American Journal of Physiology - Heart and Circulatory Physiology. 257: 26/5. PMID 2589511 DOI: 10.1152/Ajpheart.1989.257.5.H1573  0.571
1988 Morgan KG, Brozovich FV, Jiang MJ. Measurements of intracellular calcium concentration in mammalian vascular smooth muscle cells during agonist-induced contractions Biochemical Society Transactions. 16: 493. PMID 3208976 DOI: 10.1042/Bst0160493  0.351
1988 Brozovich FV, Yates LD, Gordon AM. Muscle force and stiffness during activation and relaxation. Implications for the actomyosin ATPase. The Journal of General Physiology. 91: 399-420. PMID 2967885 DOI: 10.1085/Jgp.91.3.399  0.527
1983 Brozovich FV, Pollack GH. Muscle contraction generates discrete sound bursts. Biophysical Journal. 41: 35-40. PMID 6600629 DOI: 10.1016/S0006-3495(83)84403-8  0.353
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