Hadley D. Sikes, Ph.D. - Publications

Affiliations: 
2003 Stanford University, Palo Alto, CA 
Area:
Physical Chemistry

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cavazos-Elizondo D, Sung KJ, Vasikaran S, Aguirre-Soto A, Sikes HD. Functional Comparison of Bioactive Cellulose Materials Incorporating Engineered Binding Proteins. Acs Applied Bio Materials. 4: 392-398. PMID 35014290 DOI: 10.1021/acsabm.0c01474  0.743
2021 Kim S, Martínez Dibildox A, Aguirre-Soto A, Sikes HD. Exponential Amplification Using Photoredox Autocatalysis. Journal of the American Chemical Society. PMID 34288684 DOI: 10.1021/jacs.1c04236  0.776
2020 Herzog PL, Borghi E, Traxlmayr MW, Obinger C, Sikes HD, Peterbauer CK. Developing a cell-bound detection system for the screening of oxidase activity using the fluorescent peroxide sensor roGFP2-Orp1. Protein Engineering Design & Selection. 33. PMID 32930800 DOI: 10.1093/Protein/Gzaa019  0.326
2020 Stein KT, Moon SJ, Nguyen AN, Sikes HD. Kinetic modeling of H2O2 dynamics in the mitochondria of HeLa cells. Plos Computational Biology. 16: e1008202. PMID 32925922 DOI: 10.1371/Journal.Pcbi.1008202  0.371
2020 Yee EH, Sikes HD. Polymerization-based amplification for target-specific colorimetric detection of amplified Mycobacterium tuberculosis DNA on cellulose. Acs Sensors. PMID 31970983 DOI: 10.1021/Acssensors.9B02424  0.339
2020 Kim S, Sikes HD. Radical polymerization reactions for amplified biodetection signals Polymer Chemistry. 11: 1424-1444. DOI: 10.1039/C9Py01801H  0.407
2019 Tobos CI, Kim S, Rissin DM, Johnson JM, Douglas S, Yan S, Nie S, Rice B, Sung KJ, Sikes HD, Duffy DC. Sensitivity and binding kinetics of an ultra-sensitive chemiluminescent enzyme-linked immunosorbent assay at arrays of antibodies. Journal of Immunological Methods. 112643. PMID 31401067 DOI: 10.1016/J.Jim.2019.112643  0.328
2019 Kim S, Sikes HD. Liposome-Enhanced Polymerization-Based Signal Amplification for Highly Sensitive Naked-Eye Biodetection in Paper-Based Sensors. Acs Applied Materials & Interfaces. PMID 31291078 DOI: 10.1021/Acsami.9B08125  0.361
2019 Zhang Q, Zeininger L, Sung KJ, Miller EA, Yoshinaga K, Sikes HD, Swager TM. Emulsion Agglutination Assay for the Detection of Protein-Protein Interactions: An Optical Sensor for Zika Virus. Acs Sensors. PMID 30624045 DOI: 10.1021/Acssensors.8B01202  0.305
2019 Aguirre-Soto A, Kim S, Kaastrup K, Sikes HD. On the role of N-vinylpyrrolidone in the aqueous radical-initiated copolymerization with PEGDA mediated by eosin Y in the presence of O2 Polymer Chemistry. 10: 926-937. DOI: 10.1039/C8Py01459K  0.749
2018 Stein KT, Moon SJ, Sikes HD. Mitochondrial HO generation using a tunable chemogenetic tool to perturb redox homeostasis in human cells and induce cell death. Acs Synthetic Biology. PMID 30138563 DOI: 10.1021/Acssynbio.8B00174  0.344
2018 Paloni JM, Miller EA, Sikes HD, Olsen BD. Improved Ordering in Low Molecular Weight Protein-Polymer Conjugates Through Oligomerization of the Protein Block. Biomacromolecules. PMID 30132651 DOI: 10.1021/Acs.Biomac.8B00928  0.319
2018 Langford TF, Huang BK, Lim JB, Moon SJ, Sikes HD. Monitoring the action of redox-directed cancer therapeutics using a human peroxiredoxin-2-based probe. Nature Communications. 9: 3145. PMID 30087344 DOI: 10.1038/S41467-018-05557-Y  0.778
2018 Miller EA, Jabbour Al Maalouf Y, Sikes HD. Design principles for enhancing sensitivity in paper-based diagnostics via large-volume processing. Analytical Chemistry. PMID 29924932 DOI: 10.1021/Acs.Analchem.8B02113  0.327
2018 Tam BE, Hao Y, Sikes HD. An Examination of Critical Parameters in Hybridization-Based Epigenotyping using Magnetic Microparticles. Biotechnology Progress. PMID 29693329 DOI: 10.1002/Btpr.2644  0.34
2018 Langford TF, Deen WM, Sikes HD. A mathematical analysis of Prx2-STAT3 disulfide exchange rate constants for a bimolecular reaction mechanism. Free Radical Biology & Medicine. PMID 29574146 DOI: 10.1016/J.Freeradbiomed.2018.03.039  0.367
2018 Aguirre-Soto A, Kaastrup K, Kim S, Ugo-Beke K, Sikes HD. Excitation of Metastable Intermediates in Organic Photoredox Catalysis: Z-Scheme Approach Decreases Catalyst Inactivation Acs Catalysis. 8: 6394-6400. DOI: 10.1021/Acscatal.8B00857  0.764
2018 Dellal D, Yee E, Lathwal S, Sikes H, Gomez-Marquez J. Low-cost plug and play photochemistry reactor Hardwarex. 3: 1-9. DOI: 10.1016/J.Ohx.2017.11.001  0.755
2018 Sikes HD. Quantitative analysis of cytosolic and mitochondrial H2O2 metabolism and toxicity in human epithelial cells Free Radical Biology and Medicine. 120: S14. DOI: 10.1016/J.Freeradbiomed.2018.04.063  0.345
2017 Miller EA, Baniya S, Osorio D, Al Maalouf YJ, Sikes HD. Paper-based diagnostics in the antigen-depletion regime: High-density immobilization of rcSso7d-cellulose-binding domain fusion proteins for efficient target capture. Biosensors & Bioelectronics. 102: 456-463. PMID 29182928 DOI: 10.1016/J.Bios.2017.11.050  0.318
2017 Yee EH, Lathwal S, Shah PP, Sikes HD. Detection of Biomarkers of Periodontal Disease in Human Saliva Using Stabilized, Vertical Flow Immunoassays. Acs Sensors. PMID 29090909 DOI: 10.1021/Acssensors.7B00745  0.743
2017 Sikes HD. Redox regulation: Scaffolding H2O2 signaling. Nature Chemical Biology. 13: 818-819. PMID 28853734 DOI: 10.1038/Nchembio.2432  0.303
2016 Huang BK, Stein KT, Sikes HD. Modulating and measuring intracellular H2O2 using genetically-encoded tools to study its toxicity to human cells. Acs Synthetic Biology. PMID 27428287 DOI: 10.1021/Acssynbio.6B00120  0.783
2016 Shatova TA, Lathwal S, Engle MR, Sikes HD, Jensen KF. Portable, Constriction-Expansion Blood Plasma Separation and Polymerization-Based Malaria Detection. Analytical Chemistry. PMID 27366819 DOI: 10.1021/Acs.Analchem.6B01355  0.73
2016 Heimer BW, Tam BE, Minkovsky A, Sikes HD. Using nanobiotechnology to increase the prevalence of epigenotyping assays in precision medicine. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. PMID 27126368 DOI: 10.1002/Wnan.1407  0.78
2016 Lathwal S, Sikes HD. Assessment of colorimetric amplification methods in a paper-based immunoassay for diagnosis of malaria. Lab On a Chip. 16: 1374-82. PMID 27001468 DOI: 10.1039/C6Lc00058D  0.753
2016 Huang BK, Langford TF, Sikes HD. Using sensors and generators of H2O2 to elucidate the toxicity mechanism of piperlongumine and phenethyl isothiocyanate. Antioxidants & Redox Signaling. PMID 26905788 DOI: 10.1089/Ars.2015.6482  0.782
2016 Lathwal S, Sikes HD. A Method for Designing Instrument-Free Quantitative Immunoassays. Analytical Chemistry. 88: 3194-202. PMID 26878154 DOI: 10.1021/Acs.Analchem.5B04538  0.753
2016 Kaastrup K, Aguirre-Soto A, Wang C, Bowman CN, Stansbury J, Sikes HD. UV-Vis/FT-NIR in situ monitoring of visible-light induced polymerization of PEGDA hydrogels initiated by eosin/triethanolamine/O2. Polymer Chemistry. 7: 592-602. PMID 26755925 DOI: 10.1039/C5Py01528F  0.767
2016 Kaastrup K, Sikes HD. Using photo-initiated polymerization reactions to detect molecular recognition. Chemical Society Reviews. 45: 532-45. PMID 26671512 DOI: 10.1039/C5Cs00205B  0.795
2016 Wong J, Sikes HD. The Impact of Continuous Oxygen Flux in a Thin Film Photopolymerization Reaction with Peroxy-Mediated Regeneration of Initiator Macromolecular Theory and Simulations. 25: 229-237. DOI: 10.1002/Mats.201500098  0.595
2015 Huang BK, Ali S, Stein KT, Sikes HD. Interpreting Heterogeneity in Response of Cells Expressing a Fluorescent Hydrogen Peroxide Biosensor. Biophysical Journal. 109: 2148-58. PMID 26588573 DOI: 10.1016/J.Bpj.2015.08.053  0.793
2015 Lim JB, Langford TF, Huang BK, Deen WM, Sikes HD. A reaction-diffusion model of cytosolic hydrogen peroxide. Free Radical Biology & Medicine. PMID 26561774 DOI: 10.1016/J.Freeradbiomed.2015.11.005  0.787
2015 Heimer BW, Tam BE, Sikes HD. Characterization and directed evolution of a methyl-binding domain protein for high-sensitivity DNA methylation analysis. Protein Engineering, Design & Selection : Peds. 28: 543-51. PMID 26384511 DOI: 10.1093/protein/gzv046  0.769
2015 Lim JB, Barker KA, Eller KA, Jiang L, Molina V, Saifee JF, Sikes HD. Insights into electron leakage in the reaction cycle of cytochrome P450 BM3 revealed by kinetic modeling and mutagenesis. Protein Science : a Publication of the Protein Society. PMID 26311413 DOI: 10.1002/Pro.2793  0.667
2015 Reece AE, Kaastrup K, Sikes HD, Oakey J. Staged Inertial Microfluidic Focusing for Complex Fluid Enrichment. Rsc Advances. 5: 53857-53864. PMID 26185618 DOI: 10.1039/C5Ra10634F  0.763
2015 Lim JB, Huang BK, Deen WM, Sikes HD. Analysis of the lifetime and spatial localization of hydrogen peroxide generated in the cytosol using a reduced kinetic model. Free Radical Biology & Medicine. 89: 47-53. PMID 26169725 DOI: 10.1016/J.Freeradbiomed.2015.07.009  0.789
2015 Lim JB, Sikes HD. Use of a genetically encoded hydrogen peroxide sensor for whole cell screening of enzyme activity. Protein Engineering, Design & Selection : Peds. 28: 79-83. PMID 25691762 DOI: 10.1093/Protein/Gzv003  0.667
2015 Badu-Tawiah AK, Lathwal S, Kaastrup K, Al-Sayah M, Christodouleas DC, Smith BS, Whitesides GM, Sikes HD. Polymerization-based signal amplification for paper-based immunoassays. Lab On a Chip. 15: 655-9. PMID 25427131 DOI: 10.1039/C4Lc01239A  0.77
2015 Kaastrup K, Sikes HD. Investigation of dendrimers functionalized with eosin as macrophotoinitiators for polymerization-based signal amplification reactions Rsc Advances. 5: 15652-15659. DOI: 10.1039/C4Ra14466J  0.786
2015 Wong J, Kaastrup K, Aguirre-Soto A, Sikes HD. A quantitative analysis of peroxy-mediated cyclic regeneration of eosin under oxygen-rich photopolymerization conditions Polymer (United Kingdom). 69: 169-177. DOI: 10.1016/J.Polymer.2015.05.043  0.782
2015 Lim JB, Huang BK, Deen WM, Sikes HD. Analysis of the lifetime and spatial localization of hydrogen peroxide generated in the cytosol using a reduced kinetic model Free Radical Biology and Medicine. 89: 47-53. DOI: 10.1016/j.freeradbiomed.2015.07.009  0.761
2014 Huang BK, Sikes HD. Quantifying intracellular hydrogen peroxide perturbations in terms of concentration. Redox Biology. 2: 955-962. PMID 25460730 DOI: 10.1016/J.Redox.2014.08.001  0.792
2014 Lim JB, Barker KA, Huang BK, Sikes HD. In-depth characterization of the fluorescent signal of HyPer, a probe for hydrogen peroxide, in bacteria exposed to external oxidative stress. Journal of Microbiological Methods. 106: 33-9. PMID 25109249 DOI: 10.1016/J.Mimet.2014.07.038  0.779
2014 Heimer BW, Shatova TA, Lee JK, Kaastrup K, Sikes HD. Evaluating the sensitivity of hybridization-based epigenotyping using a methyl binding domain protein. The Analyst. 139: 3695-701. PMID 24824477 DOI: 10.1039/C4An00667D  0.749
2014 Lee JK, Sikes HD. Balancing the initiation and molecular recognition capabilities of eosin macroinitiators of polymerization-based signal amplification reactions. Macromolecular Rapid Communications. 35: 981-6. PMID 24677679 DOI: 10.1002/Marc.201400035  0.633
2013 Kaastrup K, Chan L, Sikes HD. Impact of dissociation constant on the detection sensitivity of polymerization-based signal amplification reactions. Analytical Chemistry. 85: 8055-60. PMID 23919833 DOI: 10.1021/Ac4018988  0.806
2012 Kaastrup K, Sikes HD. Polymerization-based signal amplification under ambient conditions with thirty-five second reaction times. Lab On a Chip. 12: 4055-8. PMID 22930231 DOI: 10.1039/C2Lc40584A  0.803
2012 Lee JK, Heimer BW, Sikes HD. Systematic study of fluorescein-functionalized macrophotoinitiators for colorimetric bioassays. Biomacromolecules. 13: 1136-43. PMID 22404188 DOI: 10.1021/Bm300037T  0.778
2012 Boyd ME, Heimer BW, Sikes HD. Functional heterologous expression and purification of a mammalian methyl-CpG binding domain in suitable yield for DNA methylation profiling assays. Protein Expression and Purification. 82: 332-8. PMID 22326799 DOI: 10.1016/J.Pep.2012.01.016  0.771
2009 Sikes HD, Jenison R, Bowman CN. Antigen detection using polymerization-based amplification. Lab On a Chip. 9: 653-6. PMID 19224013 DOI: 10.1039/B816198D  0.522
2008 Hansen RR, Sikes HD, Bowman CN. Visual detection of labeled oligonucleotides using visible-light-polymerization-based amplification. Biomacromolecules. 9: 355-62. PMID 18052028 DOI: 10.1021/Bm700672Z  0.514
2008 Sikes HD, Hansen RR, Johnson LM, Jenison R, Birks JW, Rowlen KL, Bowman CN. Using polymeric materials to generate an amplified response to molecular recognition events. Nature Materials. 7: 52-6. PMID 17965717 DOI: 10.1038/Nmat2042  0.527
2004 Smalley JF, Sachs SB, Chidsey CE, Dudek SP, Sikes HD, Creager SE, Yu CJ, Feldberg SW, Newton MD. Interfacial electron-transfer kinetics of ferrocene through oligophenyleneethynylene bridges attached to gold electrodes as constituents of self-assembled monolayers: observation of a nonmonotonic distance dependence. Journal of the American Chemical Society. 126: 14620-30. PMID 15521782 DOI: 10.1021/Ja047458B  0.755
2003 Sikes HD, Sun Y, Dudek SP, Chidsey CED, Pianetta P. Photoelectron spectroscopy to probe the mechanism of electron transfer through oligo(phenylene vinylene) bridges Journal of Physical Chemistry B. 107: 1170-1173. DOI: 10.1021/Jp026734A  0.764
2001 Dudek SP, Sikes HD, Chidsey CED. Synthesis of ferrocenethiols containing oligo(phenylenevinylene) bridges and their characterization on gold electrodes Journal of the American Chemical Society. 123: 8033-8038. PMID 11506559 DOI: 10.1021/Ja0043340  0.775
2001 Sikes HD, Smalley JF, Dudek SP, Cook AR, Newton MD, Chidsey CE, Feldberg SW. Rapid electron tunneling through oligophenylenevinylene bridges. Science (New York, N.Y.). 291: 1519-23. PMID 11222852 DOI: 10.1126/Science.1055745  0.762
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