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Victor Ambros - Publications

Affiliations: 
University of Massachusetts Medical School, Worcester, MA, United States 
Area:
miRNA, C. elegans development
Website:
http://146.189.76.171/VRA/lab.html
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62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Duan Y, Li L, Panzade GP, Piton A, Zinovyeva A, Ambros V. Modeling neurodevelopmental disorder-associated human mutations in Argonaute . Proceedings of the National Academy of Sciences of the United States of America. 121: e2308255121. PMID 38412125 DOI: 10.1073/pnas.2308255121  0.421
2023 Duan Y, Li L, Panzade GP, Piton A, Zinovyeva A, Ambros V. Modeling neurodevelopmental disorder-associated mutations in Argonaute . Biorxiv : the Preprint Server For Biology. PMID 37066388 DOI: 10.1101/2023.04.06.535748  0.437
2021 Ilbay O, Nelson C, Ambros V. C. elegans LIN-28 controls temporal cell fate progression by regulating LIN-46 expression via the 5' UTR of lin-46 mRNA. Cell Reports. 36: 109670. PMID 34496246 DOI: 10.1016/j.celrep.2021.109670  0.307
2021 Nelson C, Ambros V. A cohort of Caenorhabditis species lacking the highly conserved let-7 microRNA. G3 (Bethesda, Md.). 11. PMID 33890616 DOI: 10.1093/g3journal/jkab022  0.304
2020 Geekiyanage H, Rayatpisheh S, Wohlschlegel JA, Brown R, Ambros V. Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides. Proceedings of the National Academy of Sciences of the United States of America. PMID 32929008 DOI: 10.1073/Pnas.2008323117  0.487
2019 Nelson C, Ambros V. Correction: Trans-splicing of the primary transcript developmentally regulates microRNA biogenesis and family microRNA activity (doi: 10.1242/dev.172031). Development (Cambridge, England). 146. PMID 31340934 DOI: 10.1242/Dev.182212  0.348
2019 Nelson C, Ambros V. Trans-splicing of the primary transcript developmentally regulates microRNA biogenesis and family microRNA activity. Development (Cambridge, England). PMID 30770392 DOI: 10.1242/dev.172031  0.353
2019 Ambros V. Mathematics of microRNAs: stabilizing gene regulatory networks National Science Review. 6: 1189-1190. DOI: 10.1093/Nsr/Nwz112  0.338
2018 Ambros V, Ruvkun G. Recent Molecular Genetic Explorations of MicroRNAs. Genetics. 209: 651-673. PMID 29967059 DOI: 10.1534/Genetics.118.300291  0.604
2017 McJunkin K, Ambros V. A microRNA family exerts maternal control on sex determination in C. elegans. Genes & Development. PMID 28279983 DOI: 10.1101/gad.290155.116  0.318
2016 Tanriverdi K, Kucukural A, Mikhalev E, Tanriverdi SE, Lee R, Ambros VR, Freedman JE. Comparison of RNA Isolation and Associated Methods for Extracellular RNA Detection by High-Throughput qPCR. Analytical Biochemistry. PMID 26969789 DOI: 10.1016/j.ab.2016.02.019  0.4
2016 Ren Z, Veksler-Lublinsky I, Morrissey D, Ambros V. Staufen Negatively Modulates microRNA Activity in Caenorhabditis elegans. G3 (Bethesda, Md.). PMID 26921297 DOI: 10.1534/g3.116.027300  0.383
2015 Zinovyeva AY, Veksler-Lublinsky I, Vashisht AA, Wohlschlegel JA, Ambros VR. Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Proceedings of the National Academy of Sciences of the United States of America. 112: E5271-80. PMID 26351692 DOI: 10.1073/Pnas.1506576112  0.367
2015 Burke SL, Hammell M, Ambros V. Robust Distal Tip Cell Pathfinding in the Face of Temperature Stress Is Ensured by Two Conserved microRNAs in Caenorhabditis elegans. Genetics. PMID 26078280 DOI: 10.1534/Genetics.115.179184  0.652
2015 Ren Z, Ambros VR. Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress. Proceedings of the National Academy of Sciences of the United States of America. 112: E2366-75. PMID 25897023 DOI: 10.1073/pnas.1422858112  0.398
2014 Ward J, Kanchagar C, Veksler-Lublinsky I, Lee RC, McGill MR, Jaeschke H, Curry SC, Ambros VR. Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis. Proceedings of the National Academy of Sciences of the United States of America. 111: 12169-74. PMID 25092309 DOI: 10.1073/pnas.1412608111  0.318
2014 Zinovyeva AY, Bouasker S, Simard MJ, Hammell CM, Ambros V. Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repression. Plos Genetics. 10: e1004286. PMID 24763381 DOI: 10.1371/Journal.Pgen.1004286  0.366
2013 Ward JA, Esa N, Pidikiti R, Freedman JE, Keaney JF, Tanriverdi K, Vitseva O, Ambros V, Lee R, McManus DD. Circulating Cell and Plasma microRNA Profiles Differ between Non-ST-Segment and ST-Segment-Elevation Myocardial Infarction. Family Medicine & Medical Science Research. 2: 108. PMID 24432306 DOI: 10.4172/2327-4972.1000108  0.389
2013 Pidikiti R, Esa N, Kinno M, Ward JA, Freedman JE, Keaney J, Ambros V, McManus D. THE PROPRIETY ROLE OF CIRCULATING MICRORNAS IN PAROXYSMAL OR PERSISTENT ATRIAL FIBRILLATION Journal of the American College of Cardiology. 61: E311. DOI: 10.1016/S0735-1097(13)60311-3  0.451
2012 Karp X, Ambros V. Dauer larva quiescence alters the circuitry of microRNA pathways regulating cell fate progression in C. elegans. Development (Cambridge, England). 139: 2177-86. PMID 22619389 DOI: 10.1242/Dev.075986  0.371
2011 Ambros V. MicroRNAs and developmental timing. Current Opinion in Genetics & Development. 21: 511-7. PMID 21530229 DOI: 10.1016/j.gde.2011.04.003  0.334
2011 Karp X, Hammell M, Ow MC, Ambros V. Effect of life history on microRNA expression during C. elegans development. Rna (New York, N.Y.). 17: 639-51. PMID 21343388 DOI: 10.1261/Rna.2310111  0.669
2010 Zheng G, Ambros V, Li WH. Inhibiting miRNA in Caenorhabditis elegans using a potent and selective antisense reagent. Silence. 1: 9. PMID 20359322 DOI: 10.1186/1758-907X-1-9  0.403
2010 Ambros V. In the tradition of science: an interview with Victor Ambros. Plos Genetics. 6: e1000853. PMID 20221254 DOI: 10.1371/Journal.Pgen.1000853  0.391
2009 Hammell CM, Karp X, Ambros V. A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 106: 18668-73. PMID 19828440 DOI: 10.1073/Pnas.0908131106  0.413
2009 Hong X, Hammell M, Ambros V, Cohen SM. Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets. Proceedings of the National Academy of Sciences of the United States of America. 106: 15085-90. PMID 19706460 DOI: 10.1073/Pnas.0908149106  0.695
2009 Zhang L, Hammell M, Kudlow BA, Ambros V, Han M. Systematic analysis of dynamic miRNA-target interactions during C. elegans development. Development (Cambridge, England). 136: 3043-55. PMID 19675127 DOI: 10.1242/Dev.039008  0.71
2009 Hammell CM, Lubin I, Boag PR, Blackwell TK, Ambros V. nhl-2 Modulates microRNA activity in Caenorhabditis elegans. Cell. 136: 926-38. PMID 19269369 DOI: 10.1016/J.Cell.2009.01.053  0.434
2008 Hammell M, Long D, Zhang L, Lee A, Carmack CS, Han M, Ding Y, Ambros V. mirWIP: microRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts. Nature Methods. 5: 813-9. PMID 19160516 DOI: 10.1038/Nmeth.1247  0.701
2008 Martinez NJ, Ow MC, Reece-Hoyes JS, Barrasa MI, Ambros VR, Walhout AJ. Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity. Genome Research. 18: 2005-15. PMID 18981266 DOI: 10.1101/gr.083055.108  0.411
2008 Ambros V. The evolution of our thinking about microRNAs. Nature Medicine. 14: 1036-40. PMID 18841144 DOI: 10.1038/nm1008-1036  0.319
2008 Martinez NJ, Ow MC, Barrasa MI, Hammell M, Sequerra R, Doucette-Stamm L, Roth FP, Ambros VR, Walhout AJ. A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity. Genes & Development. 22: 2535-49. PMID 18794350 DOI: 10.1101/Gad.1678608  0.702
2008 Ow MC, Martinez NJ, Olsen PH, Silverman HS, Barrasa MI, Conradt B, Walhout AJ, Ambros V. The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans. Genes & Development. 22: 2520-34. PMID 18794349 DOI: 10.1101/gad.1678808  0.717
2007 Miska EA, Alvarez-Saavedra E, Abbott AL, Lau NC, Hellman AB, McGonagle SM, Bartel DP, Ambros VR, Horvitz HR. Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. Plos Genetics. 3: e215. PMID 18085825 DOI: 10.1371/Journal.Pgen.0030215  0.656
2007 Long D, Lee R, Williams P, Chan CY, Ambros V, Ding Y. Potent effect of target structure on microRNA function. Nature Structural & Molecular Biology. 14: 287-94. PMID 17401373 DOI: 10.1038/Nsmb1226  0.483
2006 Lee RC, Hammell CM, Ambros V. Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans. Rna (New York, N.Y.). 12: 589-97. PMID 16489184 DOI: 10.1261/rna.2231506  0.398
2005 Karp X, Ambros V. Developmental biology. Encountering microRNAs in cell fate signaling. Science (New York, N.Y.). 310: 1288-9. PMID 16311325 DOI: 10.1126/Science.1121566  0.344
2005 Abbott AL, Alvarez-Saavedra E, Miska EA, Lau NC, Bartel DP, Horvitz HR, Ambros V. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Developmental Cell. 9: 403-14. PMID 16139228 DOI: 10.1016/J.Devcel.2005.07.009  0.547
2004 Ambros V. The functions of animal microRNAs. Nature. 431: 350-5. PMID 15372042 DOI: 10.1038/nature02871  0.437
2004 Ambros V, Lee RC. Identification of microRNAs and other tiny noncoding RNAs by cDNA cloning. Methods in Molecular Biology (Clifton, N.J.). 265: 131-58. PMID 15103073 DOI: 10.1385/1-59259-775-0:131  0.304
2004 Sempere LF, Freemantle S, Pitha-Rowe I, Moss E, Dmitrovsky E, Ambros V. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biology. 5: R13. PMID 15003116 DOI: 10.1186/Gb-2004-5-3-R13  0.496
2003 Carrington JC, Ambros V. Role of microRNAs in plant and animal development. Science (New York, N.Y.). 301: 336-8. PMID 12869753 DOI: 10.1126/Science.1085242  0.52
2003 Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V. Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity. Developmental Biology. 259: 9-18. PMID 12812784 DOI: 10.1016/S0012-1606(03)00208-2  0.429
2003 Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D. MicroRNAs and other tiny endogenous RNAs in C. elegans. Current Biology : Cb. 13: 807-18. PMID 12747828 DOI: 10.1016/S0960-9822(03)00287-2  0.447
2003 Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M, Matzke M, Ruvkun G, Tuschl T. A uniform system for microRNA annotation. Rna (New York, N.Y.). 9: 277-9. PMID 12592000 DOI: 10.1261/Rna.2183803  0.694
2001 Ambros V. microRNAs: tiny regulators with great potential. Cell. 107: 823-6. PMID 11779458 DOI: 10.1016/S0092-8674(01)00616-X  0.342
2001 Lee RC, Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science (New York, N.Y.). 294: 862-4. PMID 11679672 DOI: 10.1126/science.1065329  0.427
2000 Ambros V. Control of developmental timing in Caenorhabditis elegans. Current Opinion in Genetics & Development. 10: 428-33. PMID 10889059 DOI: 10.1016/S0959-437X(00)00108-8  0.31
2000 Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Molecular Cell. 5: 659-69. PMID 10882102 DOI: 10.1016/S1097-2765(00)80245-2  0.715
1997 Moss EG, Lee RC, Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell. 88: 637-46. PMID 9054503 DOI: 10.1016/S0092-8674(00)81906-6  0.31
1991 Liu Z, Ambros V. Alternative temporal control systems for hypodermal cell differentiation in Caenorhabditis elegans. Nature. 350: 162-5. PMID 26502479 DOI: 10.1038/350162A0  0.555
1991 Mello CC, Kramer JM, Stinchcomb D, Ambros V. Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. The Embo Journal. 10: 3959-70. PMID 1935914 DOI: 10.1002/J.1460-2075.1991.Tb04966.X  0.657
1989 Liu ZC, Ambros V. Heterochronic genes control the stage-specific initiation and expression of the dauer larva developmental program in Caenorhabditis elegans. Genes & Development. 3: 2039-49. PMID 2628162 DOI: 10.1101/Gad.3.12B.2039  0.576
1989 Ruvkun G, Ambros V, Coulson A, Waterston R, Sulston J, Horvitz HR. Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14. Genetics. 121: 501-16. PMID 2565854  0.617
1987 Ambros V, Horvitz HR. The lin-14 locus of Caenorhabditis elegans controls the time of expression of specific postembryonic developmental events. Genes & Development. 1: 398-414. PMID 3678829 DOI: 10.1101/Gad.1.4.398  0.556
1984 Ambros V, Horvitz HR. Heterochronic mutants of the nematode Caenorhabditis elegans. Science (New York, N.Y.). 226: 409-16. PMID 6494891 DOI: 10.1126/Science.6494891  0.551
1980 Ambros V, Baltimore D. Purification and properties of a HeLa cell enzyme able to remove the 5'-terminal protein from poliovirus RNA. The Journal of Biological Chemistry. 255: 6739-44. PMID 6248532  0.371
1978 Ambros V, Pettersson RF, Baltimore D. An enzymatic activity in uninfected cells that cleaves the linkage between poliovirion RNA and the 5' terminal protein. Cell. 15: 1439-46. PMID 215328 DOI: 10.1016/0092-8674(78)90067-3  0.384
1978 Pettersson RF, Ambros V, Baltimore D. Identification of a protein linked to nascent poliovirus RNA and to the polyuridylic acid of negative-strand RNA. Journal of Virology. 27: 357-65. PMID 211265 DOI: 10.1128/Jvi.27.2.357-365.1978  0.398
1978 Ambros V, Baltimore D. Protein is linked to the 5' end of poliovirus RNA by a phosphodiester linkage to tyrosine. The Journal of Biological Chemistry. 253: 5263-6. PMID 209034  0.367
1977 Hewlett MJ, Rozenblatt S, Ambros V, Baltimore D. Separation and quantitation of intracellular forms of poliovirus RNA by agarose gel electrophoresis. Biochemistry. 16: 2763-7. PMID 196620 DOI: 10.1021/Bi00631A027  0.397
1977 Flanegan JB, Petterson RF, Ambros V, Hewlett NJ, Baltimore D. Covalent linkage of a protein to a defined nucleotide sequence at the 5'-terminus of virion and replicative intermediate RNAs of poliovirus. Proceedings of the National Academy of Sciences of the United States of America. 74: 961-5. PMID 191841 DOI: 10.1073/Pnas.74.3.961  0.392
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