Nils Metzler-Nolte, Ph.D. - Publications

Institution:
Ruhr University Bochum, Bochum, Nordrhein-Westfalen, Germany

144 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kumar S, Riisom M, Jamieson SMF, Kavianinia I, Harris PWR, Metzler-Nolte N, Brimble MA, Hartinger CG. On-Resin Conjugation of the Ruthenium Anticancer Agent Plecstatin-1 to Peptide Vectors. Inorganic Chemistry. PMID 37611203 DOI: 10.1021/acs.inorgchem.3c01718  0.338
2021 Obitz D, Miller RG, Metzler-Nolte N. Synthesis and DNA interaction studies of Ru(II) cell penetrating peptide (CPP) bioconjugates. Dalton Transactions (Cambridge, England : 2003). PMID 34549219 DOI: 10.1039/d1dt01776d  0.309
2021 Gómez J, Sierra D, Ojeda C, Thavalingam S, Miller R, Guzmán F, Metzler-Nolte N. Solid-phase synthesis and evaluation of linear and cyclic ferrocenoyl/ruthenocenoyl water-soluble hexapeptides as potential antibacterial compounds. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 34292404 DOI: 10.1007/s00775-021-01877-5  0.335
2020 Beyer CD, Reback ML, Heinen N, Thavalingam S, Rosenhahn A, Metzler-Nolte N. Low fouling peptides with an all (D) amino acid sequence provide enhanced stability against proteolytic degradation while maintaining low antifouling properties. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 32830498 DOI: 10.1021/Acs.Langmuir.0C01790  0.375
2020 Gimeno MC, Luengo A, Marzo I, Reback M, Daubit IM, Fernández-Moreira V, Metzler-Nolte N. Luminescent Bimetallic Ir(III)/Au(I) Peptide Bioconjugates as Potential Theranostic Agents. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32542887 DOI: 10.1002/Chem.202002067  0.301
2020 Śmiłowicz D, Metzler-Nolte N. Bioconjugates of Co(III) complexes with Schiff base ligands and cell penetrating peptides: Solid phase synthesis, characterization and antiproliferative activity. Journal of Inorganic Biochemistry. 206: 111041. PMID 32120161 DOI: 10.1016/J.Jinorgbio.2020.111041  0.435
2020 Truong D, Sullivan MP, Tong KKH, Steel TR, Prause A, Lovett JH, Andersen JW, Jamieson SMF, Harris HH, Ott I, Weekley CM, Hummitzsch K, Söhnel T, Hanif M, Metzler-Nolte N, et al. Potent Inhibition of Thioredoxin Reductase by the Rh Derivatives of Anticancer M(arene/Cp*)(NHC)Cl Complexes. Inorganic Chemistry. PMID 32073260 DOI: 10.1021/Acs.Inorgchem.9B03640  0.38
2020 Beyer CD, Reback ML, Gopal SM, Nolte KA, Finlay JA, Clare AS, Schäfer LV, Metzler-Nolte N, Rosenhahn A. α-Aminoisobutyric Acid-Stabilized Peptide SAMs with Low Nonspecific Protein Adsorption and Resistance against Marine Biofouling Acs Sustainable Chemistry & Engineering. 8: 2665-2671. DOI: 10.1021/Acssuschemeng.9B05889  0.381
2020 Daubit IM, Wolf J, Metzler-Nolte N. Rhodium(I) and Iridium(I) N-Heterocyclic carbene complexes of imidazolium functionalized amino acids and peptides Journal of Organometallic Chemistry. 909: 121096. DOI: 10.1016/J.Jorganchem.2019.121096  0.46
2019 Śmiłowicz D, Slootweg JC, Metzler-Nolte N. Bioconjugation of Cyclometalated Gold(III) Lipoic Acid Fragments to Linear and Cyclic Breast Cancer Targeting Peptides. Molecular Pharmaceutics. PMID 31596097 DOI: 10.1021/Acs.Molpharmaceut.9B00695  0.434
2019 Daubit IM, Metzler-Nolte N. On the interaction of N-heterocyclic carbene Ir complexes with His and Cys containing peptides. Dalton Transactions (Cambridge, England : 2003). PMID 31465042 DOI: 10.1039/C9Dt01338E  0.451
2019 Miller RG, Vázquez-Hernández M, Prochnow P, Bandow JE, Metzler-Nolte N. A CuAAC Click Approach for the Introduction of Bidentate Metal Complexes to a Sulfanilamide-Derived Antibiotic Fragment. Inorganic Chemistry. PMID 31246015 DOI: 10.1021/Acs.Inorgchem.9B01186  0.407
2019 Graf M, Siegmund D, Metzler-Nolte N, Sünkel K, Böttcher H. Synthesis, characterization and studies on the biological activity of bis-cyclometalated M(III)-complexes (M = Rh, Ir and Ru) Inorganica Chimica Acta. 487: 9-14. DOI: 10.1016/J.Ica.2018.11.050  0.371
2018 Weiss LC, Albada B, Becker SM, Meckelmann SW, Klein J, Meyer M, Schmitz OJ, Sommer U, Leo M, Zagermann J, Metzler-Nolte N, Tollrian R. Identification of Chaoborus kairomone chemicals that induce defences in Daphnia. Nature Chemical Biology. PMID 30429602 DOI: 10.1038/S41589-018-0164-7  0.314
2018 Smiłowicz D, Metzler-Nolte N. Synthesis of monofunctional platinum(iv) carboxylate precursors for use in Pt(iv)-peptide bioconjugates. Dalton Transactions (Cambridge, England : 2003). PMID 30334055 DOI: 10.1039/C8Dt03082K  0.421
2018 Battistin F, Siegmund D, Balducci G, Alessio E, Metzler-Nolte N. Ru(ii)-Peptide bioconjugates with the cppH linker (cppH = 2-(2'-pyridyl)pyrimidine-4-carboxylic acid): synthesis, structural characterization, and different stereochemical features between organic and aqueous solvents. Dalton Transactions (Cambridge, England : 2003). PMID 30285015 DOI: 10.1039/C8Dt03575J  0.409
2018 Muñoz-Osses M, Siegmund D, Gómez A, Godoy F, Fierro A, Llanos L, Aravena D, Metzler-Nolte N. Influence of the substituent on the phosphine ligand in novel rhenium(i) aldehydes. Synthesis, computational studies and first insights into the antiproliferative activity. Dalton Transactions (Cambridge, England : 2003). PMID 30225486 DOI: 10.1039/C8Dt03160F  0.38
2018 König M, Siegmund D, Raszeja LJ, Prokop A, Metzler-Nolte N. Resistance-breaking profiling and gene expression analysis on an organometallic Re-phenanthridine complex reveal parallel activation of two apoptotic pathways. Medchemcomm. 9: 173-180. PMID 30108911 DOI: 10.1039/C7Md00545H  0.308
2018 Lipiński PFJ, Garnuszek P, Maurin M, Stoll R, Metzler-Nolte N, Wodyński A, Dobrowolski JC, Dudek MK, Orzełowska M, Mikołajczak R. Structural studies on radiopharmaceutical DOTA-minigastrin analogue (CP04) complexes and their interaction with CCK2 receptor. Ejnmmi Research. 8: 33. PMID 29663167 DOI: 10.1186/S13550-018-0387-3  0.334
2018 Muñoz-Osses M, Godoy F, Fierro A, Gómez A, Metzler-Nolte N. New organometallic imines of rhenium(i) as potential ligands of GSK-3β: synthesis, characterization and biological studies. Dalton Transactions (Cambridge, England : 2003). PMID 29299575 DOI: 10.1039/C7Dt04344A  0.367
2018 Graf M, Gothe Y, Siegmund D, Metzler-Nolte N, Sünkel K. Synthesis and characterization of cyclometallated rhodium(III) and iridium(III) compounds with antiproliferative activities in the nanomolar range Inorganica Chimica Acta. 471: 265-271. DOI: 10.1016/J.Ica.2017.11.003  0.396
2017 Siegmund D, Lorenz N, Gothe Y, Spies C, Geissler B, Prochnow P, Nuernberger P, Bandow JE, Metzler-Nolte N. Benzannulated Re(i)-NHC complexes: synthesis, photophysical properties and antimicrobial activity. Dalton Transactions (Cambridge, England : 2003). PMID 29068017 DOI: 10.1039/C7Dt02874A  0.373
2017 Albada B, Metzler-Nolte N. Highly Potent Antibacterial Organometallic Peptide Conjugates. Accounts of Chemical Research. PMID 28953347 DOI: 10.1021/Acs.Accounts.7B00282  0.444
2017 Graf M, Gothe Y, Metzler-Nolte N, Czerwieniec R, Sünkel K. Bis-cyclometalated rhodium- and iridium-complexes with the 4,4′-dichloro-2,2′-bipyridine ligand. Evaluation of their photophysical properties and biological activity Inorganica Chimica Acta. 463: 36-43. DOI: 10.1016/J.Ica.2017.04.006  0.37
2016 Raszeja LJ, Siegmund D, Cordes AL, Güldenhaupt J, Gerwert K, Hahn S, Metzler-Nolte N. Asymmetric rhenium tricarbonyl complexes show superior luminescence properties in live cell imaging. Chemical Communications (Cambridge, England). PMID 28008445 DOI: 10.1039/C6Cc07553C  0.333
2016 Albada B, Metzler-Nolte N. Organometallic-Peptide Bioconjugates: Synthetic Strategies and Medicinal Applications. Chemical Reviews. PMID 27627217 DOI: 10.1021/Acs.Chemrev.6B00166  0.413
2016 Wenzel M, Prochnow P, Mowbray C, Vuong C, Höxtermann S, Stepanek JJ, Albada HB, Hall J, Metzler-Nolte N, Bandow JE. Towards Profiles of Resistance Development and Toxicity for the Small Cationic Hexapeptide RWRWRW-NH2. Frontiers in Cell and Developmental Biology. 4: 86. PMID 27617260 DOI: 10.3389/Fcell.2016.00086  0.347
2016 Gothe Y, Marzo T, Messori L, Metzler-Nolte N. Iridium(I) Compounds as Prospective Anticancer Agents: Solution Chemistry, Antiproliferative Profiles and Protein Interactions for a Series of Iridium(I) N-Heterocyclic Carbene Complexes. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27443984 DOI: 10.1002/Chem.201601542  0.365
2016 Hoffknecht BC, Prochnow P, Bandow JE, Metzler-Nolte N. Influence of metallocene substitution on the antibacterial activity of multivalent peptide conjugates. Journal of Inorganic Biochemistry. PMID 26988572 DOI: 10.1016/J.Jinorgbio.2016.02.036  0.422
2016 Gretarsdóttir JM, Bobersky S, Metzler-Nolte N, Suman SG. Cytotoxicity studies of water soluble coordination compounds with a [Mo2O2S2](2+) core. Journal of Inorganic Biochemistry. PMID 26920227 DOI: 10.1016/J.Jinorgbio.2016.01.020  0.326
2016 Bodner EJ, Kandiyote NS, Lutskiy M, Albada HB, Metzler-Nolte N, Uhl W, Kasher R, Arnusch CJ. Attachment of antimicrobial peptides to reverse osmosis membranes by Cu(i)-catalyzed 1,3-dipolar alkyne–azide cycloaddition Rsc Advances. 6: 91815-91823. DOI: 10.1039/C6Ra21930F  0.305
2016 Esselborn J, Muraki N, Klein K, Engelbrecht V, Metzler-Nolte N, Apfel UP, Hofmann E, Kurisu G, Happe T. A structural view of synthetic cofactor integration into [FeFe]-hydrogenases Chemical Science. 7: 959-968. DOI: 10.1039/C5Sc03397G  0.312
2016 De Gier MG, Bauke Albada H, Josten M, Willems R, Leavis H, Van Mansveld R, Paganelli FL, Dekker B, Lammers JWJ, Sahl HG, Metzler-Nolte N. Synergistic activity of a short lipidated antimicrobial peptide (lipoAMP) and colistin or tobramycin against Pseudomonas aeruginosa from cystic fibrosis patients Medchemcomm. 7: 148-156. DOI: 10.1039/C5Md00373C  0.338
2016 Slootweg JC, Albada HB, Siegmund D, Metzler-Nolte N. Efficient Reagent-Saving Method for the N-Terminal Labeling of Bioactive Peptides with Organometallic Carboxylic Acids by Solid-Phase Synthesis Organometallics. 35: 3192-3196. DOI: 10.1021/Acs.Organomet.6B00544  0.443
2015 Leonidova A, Foerster C, Zarschler K, Schubert M, Pietzsch HJ, Steinbach J, Bergmann R, Metzler-Nolte N, Stephan H, Gasser G. demonstration of an active tumor pretargeting approach with peptide nucleic acid bioconjugates as complementary system. Chemical Science. 6: 5601-5616. PMID 29861898 DOI: 10.1039/C5Sc00951K  0.502
2015 Patra M, Wenzel M, Prochnow P, Pierroz V, Gasser G, Bandow JE, Metzler-Nolte N. An organometallic structure-activity relationship study reveals the essential role of a Re(CO)3 moiety in the activity against gram-positive pathogens including MRSA. Chemical Science. 6: 214-224. PMID 28553471 DOI: 10.1039/C4Sc02709D  0.65
2015 Wenzel M, Schriek P, Prochnow P, Bauke Albada H, Metzler-Nolte N, Bandow JE. Influence of lipidation on the mode of action of a small RW-rich antimicrobial peptide. Biochimica Et Biophysica Acta. PMID 26603779 DOI: 10.1016/J.Bbamem.2015.11.009  0.387
2015 Mügge C, Marzo T, Massai L, Hildebrandt J, Ferraro G, Rivera-Fuentes P, Metzler-Nolte N, Merlino A, Messori L, Weigand W. Platinum(II) Complexes with O,S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding. Inorganic Chemistry. 54: 8560-70. PMID 26280387 DOI: 10.1021/Acs.Inorgchem.5B01238  0.344
2015 Maschke M, Grohmann J, Nierhaus C, Lieb M, Metzler-Nolte N. Peptide Bioconjugates of Electron-Poor Metallocenes: Synthesis, Characterization, and Anti-Proliferative Activity. Chembiochem : a European Journal of Chemical Biology. 16: 1333-42. PMID 26012853 DOI: 10.1002/Cbic.201500060  0.421
2015 Gross A, Alborzinia H, Piantavigna S, Martin LL, Wölfl S, Metzler-Nolte N. Vesicular disruption of lysosomal targeting organometallic polyarginine bioconjugates. Metallomics : Integrated Biometal Science. 7: 371-84. PMID 25608481 DOI: 10.1039/C4Mt00255E  0.422
2015 Leonidova A, Foerster C, Zarschler K, Schubert M, Pietzsch HJ, Steinbach J, Bergmann R, Metzler-Nolte N, Stephan H, Gasser G. In vivo demonstration of an active tumor pretargeting approach with peptide nucleic acid bioconjugates as complementary system Chemical Science. 6: 5601-5616. DOI: 10.1039/c5sc00951k  0.495
2015 Patra M, Wenzel M, Prochnow P, Pierroz V, Gasser G, Bandow JE, Metzler-Nolte N. An organometallic structure-activity relationship study reveals the essential role of a Re(CO)3 moiety in the activity against gram-positive pathogens including MRSA Chemical Science. 6: 214-224. DOI: 10.1039/c4sc02709d  0.584
2015 Strack M, Langklotz S, Bandow JE, Metzler-Nolte N, Bauke Albada H. Synthesis of bisarylethyne-peptide conjugates Organic Chemistry Frontiers. 2: 531-535. DOI: 10.1039/C4Qo00357H  0.429
2015 Hoffknecht BC, Albada HB, Sturm M, Prochnow P, Bandow JE, Metzler-Nolte N. Synthesis and antibacterial activity of trivalent ultrashort Arg-Trp-based antimicrobial peptides (AMPs) Medchemcomm. 6: 372-376. DOI: 10.1039/C4Md00327F  0.466
2015 Bulfield D, Maschke M, Lieb M, Metzler-Nolte N. Synthesis, chemical reactivity and electrochemical behaviour of mono- and difluoro metallocenes Journal of Organometallic Chemistry. 797: 125-130. DOI: 10.1016/J.Jorganchem.2015.07.018  0.363
2015 Maschke M, Merz K, Shishkin OV, Zubatyuk RI, Metzler-Nolte N. Influence of chlorine substituents on the aggregation behavior of chlorobenzoyl-substituted ferrocene derivates Structural Chemistry. DOI: 10.1007/S11224-015-0587-7  0.303
2015 Graf M, Gothe Y, Metzler-Nolte N, Czerwieniec R, Sünkel K. Cyclometalated Iridium(III) Complexes Containing Semicarbazone Ligands: Synthesis, Characterization, Photophysical and Biological Studies Zeitschrift Fur Anorganische Und Allgemeine Chemie. DOI: 10.1002/Zaac.201500240  0.375
2014 Wenzel M, Chiriac AI, Otto A, Zweytick D, May C, Schumacher C, Gust R, Albada HB, Penkova M, Krämer U, Erdmann R, Metzler-Nolte N, Straus SK, Bremer E, Becher D, et al. Small cationic antimicrobial peptides delocalize peripheral membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 111: E1409-18. PMID 24706874 DOI: 10.1073/Pnas.1319900111  0.381
2014 Kitanovic I, Can S, Alborzinia H, Kitanovic A, Pierroz V, Leonidova A, Pinto A, Spingler B, Ferrari S, Molteni R, Steffen A, Metzler-Nolte N, Wölfl S, Gasser G. A deadly organometallic luminescent probe: anticancer activity of a ReI bisquinoline complex. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 2496-507. PMID 24464824 DOI: 10.1002/Chem.201304012  0.443
2014 Strack M, Metzler-Nolte N, Albada HB. Copper-free cleavage-Sonogashira conjugation of silylacetylene immobilized peptides Synthesis (Germany). 46: 2293-2296. DOI: 10.1055/S-0034-1378207  0.354
2014 Albada HB, Prochnow P, Bobersky S, Bandow JE, Metzler-Nolte N. Highly active antibacterial ferrocenoylated or ruthenocenoylated Arg-Trp peptides can be discovered by an l-to-d substitution scan Chemical Science. 5: 4453-4459. DOI: 10.1039/C4Sc01822B  0.4
2014 Graf M, Gothe Y, Metzler-Nolte N, Czerwieniec R, Sünkel K. Photophysical and biological characterization of new cationic cyclometalated M(III) complexes of rhodium and iridium Dedicated to Prof. Ingo-Peter Lorenz on the occasion of his 70th birthday. Journal of Organometallic Chemistry. 765: 46-52. DOI: 10.1016/J.Jorganchem.2014.04.031  0.345
2013 Strack M, Metzler-Nolte N, Albada HB. C-terminal acetylene derivatized peptides via silyl-based alkyne immobilization Organic Letters. 15: 3126-3129. PMID 24490777 DOI: 10.1021/Ol401332R  0.409
2013 Gross A, Habig D, Metzler-Nolte N. Synthesis and structure-activity relationship study of organometallic bioconjugates of the cyclic octapeptide octreotate Chembiochem. 14: 2472-2479. PMID 24218362 DOI: 10.1002/cbic.201300450  0.318
2013 Albada HB, Prochnow P, Bobersky S, Langklotz S, Bandow JE, Metzler-Nolte N. Short antibacterial peptides with significantly reduced hemolytic activity can be identified by a systematic l-to-d exchange scan of their amino acid residues Acs Combinatorial Science. 15: 585-592. PMID 24147906 DOI: 10.1021/Co400072Q  0.401
2013 Wenzel M, Patra M, Senges CH, Ott I, Stepanek JJ, Pinto A, Prochnow P, Vuong C, Langklotz S, Metzler-Nolte N, Bandow JE. Analysis of the mechanism of action of potent antibacterial hetero-tri-organometallic compounds: a structurally new class of antibiotics. Acs Chemical Biology. 8: 1442-50. PMID 23578171 DOI: 10.1021/Cb4000844  0.585
2013 Rubbiani R, Schuh E, Meyer A, Lemke J, Wimberg J, Metzler-Nolte N, Meyer F, Mohr F, Ott I. TrxR inhibition and antiproliferative activities of structurally diverse gold N-heterocyclic carbene complexes Medchemcomm. 4: 942-948. DOI: 10.1039/C3Md00076A  0.362
2012 Albada HB, Prochnow P, Bobersky S, Langklotz S, Schriek P, Bandow JE, Metzler-Nolte N. Tuning the activity of a short arg-trp antimicrobial Peptide by lipidation of a C- or N-terminal lysine side-chain. Acs Medicinal Chemistry Letters. 3: 980-4. PMID 24900420 DOI: 10.1021/Ml300148V  0.397
2012 Albada HB, Chiriac AI, Wenzel M, Penkova M, Bandow JE, Sahl HG, Metzler-Nolte N. Modulating the activity of short arginine-tryptophan containing antibacterial peptides with N-terminal metallocenoyl groups. Beilstein Journal of Organic Chemistry. 8: 1753-64. PMID 23209509 DOI: 10.3762/Bjoc.8.200  0.406
2012 Strack M, Langklotz S, Bandow JE, Metzler-Nolte N, Albada HB. Silyl-based alkyne-modifying linker for the preparation of C-terminal acetylene-derivatized protected peptides Journal of Organic Chemistry. 77: 9954-9958. PMID 23116417 DOI: 10.1021/Jo302305D  0.419
2012 Gross A, Hüsken N, Schur J, Raszeja ?, Ott I, Metzler-Nolte N. A ruthenocene-PNA bioconjugate - Synthesis, characterization, cytotoxicity, and AAS-detected cellular uptake Bioconjugate Chemistry. 23: 1764-1774. PMID 22823488 DOI: 10.1021/Bc200692G  0.41
2012 Albada HB, Wieberneit F, Dijkgraaf I, Harvey JH, Whistler JL, Stoll R, Metzler-Nolte N, Fish RH. The chemoselective reactions of tyrosine-containing G-protein-coupled receptor peptides with [Cp*Rh(H2O)3](OTf)2, including 2D NMR structures and the biological consequences. Journal of the American Chemical Society. 134: 10321-4. PMID 22671299 DOI: 10.1021/Ja303010K  0.418
2012 Yamamoto N, Bryce NS, Metzler-Nolte N, Hambley TW. Effects of enzymatic activation on the distribution of fluorescently tagged MMP-2 cleavable peptides in cancer cells and spheroids Bioconjugate Chemistry. 23: 1110-1118. PMID 22621307 DOI: 10.1021/Bc200561N  0.352
2012 Patra M, Gasser G, Metzler-Nolte N. Small organometallic compounds as antibacterial agents Dalton Transactions. 41: 6350-6358. PMID 22411216 DOI: 10.1039/C2Dt12460B  0.627
2012 Gasser G, Metzler-Nolte N. The potential of organometallic complexes in medicinal chemistry Current Opinion in Chemical Biology. 16: 84-91. PMID 22366385 DOI: 10.1016/J.Cbpa.2012.01.013  0.556
2012 Gaviglio L, Gross A, Metzler-Nolte N, Ravera M. Synthesis and in vitro cytotoxicity of cis,cis,trans- diamminedichloridodisuccinatoplatinum(iv)-peptide bioconjugates Metallomics. 4: 260-266. PMID 22310724 DOI: 10.1039/C2Mt00171C  0.407
2012 Abramkin S, Valiahdi SM, Jakupec MA, Galanski M, Metzler-Nolte N, Keppler BK. Solid-phase synthesis of oxaliplatin-TAT peptide bioconjugates Dalton Transactions. 41: 3001-3005. PMID 22281694 DOI: 10.1039/C2Dt12024K  0.395
2012 Gasser G, Pinto A, Neumann S, Sosniak AM, Seitz M, Merz K, Heumann R, Metzler-Nolte N. Synthesis, characterisation and bioimaging of a fluorescent rhenium-containing PNA bioconjugate Dalton Transactions. 41: 2304-2313. PMID 22183093 DOI: 10.1039/C2Dt12114J  0.553
2012 Patra M, Merz K, Metzler-Nolte N. Planar chiral (η 6-arene)Cr(CO) 3 containing carboxylic acid derivatives: Synthesis and use in the preparation of organometallic analogues of the antibiotic platensimycin Dalton Transactions. 41: 112-117. PMID 22071449 DOI: 10.1039/C1Dt10918A  0.583
2012 Köster SD, Alborzinia H, Can S, Kitanovic I, Wölfl S, Rubbiani R, Ott I, Riesterer P, Prokop A, Merz K, Metzler-Nolte N. A spontaneous gold(i)-azide alkyne cycloaddition reaction yields gold-peptide bioconjugates which overcome cisplatin resistance in a p53-mutant cancer cell line Chemical Science. 3: 2062-2072. DOI: 10.1039/C2Sc01127A  0.399
2012 Patra M, Gasser G, Wenzel M, Merz K, Bandow JE, Metzler-Nolte N. Sandwich and half-sandwich derivatives of platensimycin: Synthesis and biological evaluation Organometallics. 31: 5760-5771. DOI: 10.1021/Om201146C  0.679
2011 Patra M, Metzler-Nolte N. Azidomethyl-ruthenocene: Facile synthesis of a useful metallocene derivative and its application in the 'click' labelling of biomolecules Chemical Communications. 47: 11444-11446. PMID 21935541 DOI: 10.1039/C1Cc14537A  0.587
2011 Gasser G, Sosniak AM, Metzler-Nolte N. Metal-containing peptide nucleic acid conjugates Dalton Transactions. 40: 7061-7076. PMID 21541385 DOI: 10.1039/C0Dt01706J  0.574
2011 Wenzel M, Patra M, Albrecht D, Chen DY, Nicolaou KC, Metzler-Nolte N, Bandow JE. Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism-of-action studies. Antimicrobial Agents and Chemotherapy. 55: 2590-6. PMID 21383089 DOI: 10.1128/Aac.00078-11  0.557
2011 Raszeja L, Maghnouj A, Hahn S, Metzler-Nolte N. A novel organometallic ReI complex with favourable properties for bioimaging and applicability in solid-phase peptide synthesis. Chembiochem : a European Journal of Chemical Biology. 12: 371-6. PMID 21290535 DOI: 10.1002/Cbic.201000576  0.379
2011 Gross A, Neukamm M, Metzler-Nolte N. Synthesis and cytotoxicity of a bimetallic ruthenocene dicobalt- hexacarbonyl alkyne peptide bioconjugate Dalton Transactions. 40: 1382-1386. PMID 21180777 DOI: 10.1039/C0Dt01113D  0.436
2011 Zagermann J, Molon M, Metzler-Nolte N. Microwave-assisted synthesis of the Tp sandwich compound TpRu(p-Br-C 6H4Tp) and application of its benzoic acid derivative TpRu(p-(CO2H)-C6H4Tp) in the covalent labelling of biomolecules Dalton Transactions. 40: 1011-1015. PMID 21103532 DOI: 10.1039/C0Dt01121E  0.383
2011 Gasser G, Ott I, Metzler-Nolte N. Organometallic anticancer compounds Journal of Medicinal Chemistry. 54: 3-25. PMID 21077686 DOI: 10.1021/Jm100020W  0.554
2011 Gasser G, Sosniak AM, Leonidova A, Braband H, Metzler-Nolte N. Towards the preparation of novel Re/99mTc tricarbonyl-containing peptide nucleic acid bioconjugates Australian Journal of Chemistry. 64: 265-272. DOI: 10.1071/Ch11010  0.598
2011 Castañeda ICH, Ulic SE, Védova COD, Metzler-Nolte N, Jios JL. One-pot synthesis of 2-trifluoromethylchromones Tetrahedron Letters. 52: 1436-1440. DOI: 10.1016/J.Tetlet.2011.01.045  0.327
2011 Zagermann J, Deally A, Metzler-Nolte N, Müller-Bunz H, Wallis D, Tacke M. Towards peptide-substituted titanocene anticancer drugs Polyhedron. 30: 2387-2390. DOI: 10.1016/J.Poly.2011.05.036  0.397
2011 Nawaz S, Isab AA, Merz K, Vasylyeva V, Metzler-Nolte N, Saleem M, Ahmad S. Synthesis, characterization and antimicrobial studies of mixed ligand silver(I) complexes of triphenylphosphine and heterocyclic thiones: Crystal structure of bis[{(μ2-diazinane-2-thione)(diazinane-2-thione) (triphenylphosphine)silver(I) nitrate}] Polyhedron. 30: 1502-1506. DOI: 10.1016/J.Poly.2011.02.054  0.343
2011 Lemke J, Metzler-Nolte N. Organometallic peptide NHC complexes of CpRh(III) and arene Ru(II) moieties from l-thiazolylalanine Journal of Organometallic Chemistry. 696: 1018-1022. DOI: 10.1016/J.Jorganchem.2010.12.044  0.44
2011 Malik MR, Vasylyeva V, Merz K, Metzler-Nolte N, Saleem M, Ali S, Isab AA, Munawar KS, Ahmad S. Synthesis, crystal structures, antimicrobial properties and enzyme inhibition studies of zinc(II) complexes of thiones Inorganica Chimica Acta. 376: 207-211. DOI: 10.1016/J.Ica.2011.06.017  0.36
2011 Gasser G, Neumann S, Ott I, Seitz M, Heumann R, Metzler-Nolte N. Preparation and biological evaluation of Di-hetero-organometallic- containing PNA bioconjugates European Journal of Inorganic Chemistry. 5471-5478. DOI: 10.1002/Ejic.201100734  0.525
2011 Patra M, Gasser G, Wenzel M, Merz K, Bandow JE, Metzler-Nolte N. Synthesis of optically active ferrocene-containing platensimycin derivatives with a C6-C7 substitution pattern European Journal of Inorganic Chemistry. 3295-3302. DOI: 10.1002/Ejic.201100497  0.611
2011 Zagermann J, Klein K, Merz K, Molon M, Metzler-Nolte N. Synthesis and characterization of the azido-functionalized ruthenocene analogue [TpmRu(p-N3C6H4)Tp]Cl and its attachment to biomolecules by copper-catalyzed azide-alkyne cycloaddition European Journal of Inorganic Chemistry. 4212-4219. DOI: 10.1002/Ejic.201100433  0.342
2011 Gasser G, Metzler-Nolte N. Metal Compounds as Enzyme Inhibitors Bioinorganic Medicinal Chemistry. 351-382. DOI: 10.1002/9783527633104.ch12  0.421
2010 Gasser G, Jäger K, Zenker M, Bergmann R, Steinbach J, Stephan H, Metzler-Nolte N. Preparation, 99mTc-labeling and biodistribution studies of a PNA oligomer containing a new ligand derivative of 2,2'-dipicolylamine Journal of Inorganic Biochemistry. 104: 1133-1140. PMID 20674031 DOI: 10.1016/J.Jinorgbio.2010.06.011  0.521
2010 Fränzel B, Frese C, Penkova M, Metzler-Nolte N, Bandow JE, Wolters DA. Corynebacterium glutamicum exhibits a membrane-related response to a small ferrocene-conjugated antimicrobial peptide Journal of Biological Inorganic Chemistry. 15: 1293-1303. PMID 20658302 DOI: 10.1007/S00775-010-0689-Z  0.38
2010 Patra M, Gasser G, Bobukhov D, Merz K, Shtemenko AV, Metzler-Nolte N. Sequential insertion of three different organometallics into a versatile building block containing a PNA backbone Dalton Transactions. 39: 5617-5619. PMID 20485811 DOI: 10.1039/C003598J  0.668
2010 Patra M, Gasser G, Wenzel M, Merz K, Bandow JE, Metzler-Nolte N. Synthesis and biological evaluation of ferrocene-containing bioorganometallics inspired by the antibiotic platensimycin lead structure Organometallics. 29: 4312-4319. DOI: 10.1021/Om100614C  0.681
2009 Lemke J, Pinto A, Niehoff P, Vasylyeva V, Metzler-Nolte N. Synthesis, structural characterisation and anti-proliferative activity of NHC gold amino acid and peptide conjugates Dalton Transactions. 7063-7070. PMID 20449149 DOI: 10.1039/B906140A  0.448
2009 Sosniak AM, Gasser G, Metzler-Nolte N. Thermal melting studies of alkyne- and ferrocene-containing PNA bioconjugates Organic and Biomolecular Chemistry. 7: 4992-5000. PMID 19907791 DOI: 10.1039/B913964H  0.517
2009 Chelmowski R, Käfer D, Köster SD, Klasen T, Winkler T, Terfort A, Metzler-Nolte N, Wöll C. Postformation Modification of SAMs: using click chemistry to functionalize organic surfaces. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 11480-5. PMID 19788212 DOI: 10.1021/La9012813  0.303
2009 Patra M, Gasser G, Pinto A, Merz K, Ott I, Bandow JE, Metzler-Nolte N. Synthesis and biological evaluation of chromium bioorganometallics based on the antibiotic platensimycin lead structure Chemmedchem. 4: 1930-1938. PMID 19784974 DOI: 10.1002/Cmdc.200900347  0.629
2009 Gasser G, Brosch O, Ewers A, Weyhermüller T, Metzler-Nolte N. Synthesis and characterisation of hetero-bimetallic organometallic phenylalanine and PNA monomer derivatives Dalton Transactions. 4310-4317. PMID 19662308 DOI: 10.1039/B819169G  0.59
2009 Hüsken N, Gasser G, Köster SD, Metzler-Nolte N. "Four-potential" ferrocene labeling of PNA oligomers via click chemistry Bioconjugate Chemistry. 20: 1578-1586. PMID 19586015 DOI: 10.1021/Bc9001272  0.534
2009 Pinto A, Hoffmans U, Ott M, Fricker G, Metzler-Nolte N. Modification with organometallic compounds improves crossing of the blood-brain barrier of [Leu5]-enkephalin derivatives in an in vitro model system Chembiochem. 10: 1852-1860. PMID 19569087 DOI: 10.1002/Cbic.200900157  0.322
2009 Gasser G, Neukamm MA, Ewers A, Brosch O, Weyhermüller T, Metzler-Nolte N. Synthesis and characterization of dicobalthexacarbonyl-alkyne derivatives of amino acids, peptides, and peptide nucleic acid (PNA) monomers Inorganic Chemistry. 48: 3157-3166. PMID 19326929 DOI: 10.1021/Ic900013R  0.607
2009 Rhode C, Lemke J, Lieb M, Metzler-Nolte N. Synthesis of perfluoroalkylthio-substituted ferrocenes Synthesis. 2015-2018. DOI: 10.1055/S-0029-1216812  0.34
2009 Zagermann J, Merz K, Metzler-Nolte N. Labeling of peptides with halocarbonyltungsten complexes containing functional η2-Alkynyl ligands Organometallics. 28: 5090-5095. DOI: 10.1021/Om9002297  0.363
2009 Gross A, Metzler-Nolte N. Synthesis and characterisation of a ruthenocenoyl bioconjugate with the cyclic octapeptide octreotate Journal of Organometallic Chemistry. 694: 1185-1188. DOI: 10.1016/J.Jorganchem.2008.09.071  0.44
2009 Zagermann J, Kuchta MC, Merz K, Metzler-Nolte N. Ruthenium-based bioconjugates: Synthesis and X-ray structure of the mixed ligand sandwich compound RuCpiPr(p-(CO2H)C6H4Tp) and labelling of amino acids and the neuropeptide enkephalin Journal of Organometallic Chemistry. 694: 862-867. DOI: 10.1016/J.Jorganchem.2008.09.023  0.379
2009 Kirin SI, Schatzschneider U, Köster SD, Siebler D, Metzler-Nolte N. A systematic evaluation of different hydrogen bonding patterns in unsymmetrical 1,n′-disubstituted ferrocenoyl peptides Inorganica Chimica Acta. 362: 894-906. DOI: 10.1016/J.Ica.2008.01.050  0.38
2008 Chelmowski R, Köster SD, Kerstan A, Prekelt A, Grunwald C, Winkler T, Metzler-Nolte N, Terfort A, Wöll C. Peptide-based SAMs that resist the adsorption of proteins. Journal of the American Chemical Society. 130: 14952-3. PMID 18928285 DOI: 10.1021/Ja8065754  0.324
2008 Gasser G, Hüsken N, Köster SD, Metzler-Nolte N. Synthesis of organometallic PNA oligomers by click chemistry. Chemical Communications (Cambridge, England). 3675-7. PMID 18665296 DOI: 10.1039/B805369C  0.588
2008 Neukamm MA, Pinto A, Metzler-Nolte N. Synthesis and cytotoxicity of a cobaltcarbonyl-alkyne enkephalin bioconjugate. Chemical Communications (Cambridge, England). 232-4. PMID 18092097 DOI: 10.1039/B712886J  0.397
2008 Köster SD, Dittrich J, Gasser G, Hüsken N, Castañeda ICH, Jios JL, Védova COD, Metzler-Nolte N. Spectroscopic and electrochemical studies of ferrocenyl triazole amino acid and peptide bioconjugates synthesized by click chemistry Organometallics. 27: 6326-6332. DOI: 10.1021/Om800639M  0.594
2008 De Hatten X, Bothe E, Merz K, Huc I, Metzler-Nolte N. A ferrocene-peptide conjugate as a hydrogenase model system European Journal of Inorganic Chemistry. 4530-4537. DOI: 10.1002/Ejic.200800566  0.416
2007 Kuchta MC, Gross A, Pinto A, Metzler-Nolte N. Labeling of the neuropeptide enkephalin with functionalized tris(pyrazolyl)borate complexes: solid-phase synthesis and characterization of p-[Enk-OH]COC6H4TpPtMe3 and p-[Enk-OH]COC6H4TpMeRe(CO)3. Inorganic Chemistry. 46: 9400-4. PMID 17902654 DOI: 10.1021/Ic701316N  0.35
2007 Metzler-Nolte N. Medicinal applications of metal-peptide bioconjugates Chimia. 61: 736-741. DOI: 10.2533/Chimia.2007.736  0.405
2007 Caddy J, Hoffmanns U, Metzler-Nolte N. Introduction of phosphine-gold(I) precursors into a Cys-modified enkephalin neuropeptide as part of solid phase peptide synthesis Zeitschrift Fur Naturforschung - Section B Journal of Chemical Sciences. 62: 460-466. DOI: 10.1515/Znb-2007-0321  0.416
2007 Kirin SI, Noor F, Metzler-Nolte N, Mier W. Manual Solid–Phase Peptide Synthesis of Metallocene–Peptide Bioconjugates Journal of Chemical Education. 84: 108-111. DOI: 10.1021/Ed084P108  0.348
2007 Jios JL, Kirin SI, Buceta NN, Weyhermüller T, Della Védova CO, Metzler-Nolte N. Synthesis and structural characterization of metallated bioconjugates: C-terminal labeling of amino acids with aminoferrocene Journal of Organometallic Chemistry. 692: 4209-4214. DOI: 10.1016/J.Jorganchem.2007.06.044  0.376
2007 Kuchta MC, Gemel C, Metzler-Nolte N. An amino acid bioconjugate of an organoplatinum tris(pyrazolyl)borate complex: Synthesis and structure of [p-(tBuO-Phe-CO)C6H4Tp]PtMe3 Journal of Organometallic Chemistry. 692: 1310-1314. DOI: 10.1016/J.Jorganchem.2006.10.028  0.388
2006 Chantson JT, Verga Falzacappa MV, Crovella S, Metzler-Nolte N. Solid-phase synthesis, characterization, and antibacterial activities of metallocene-peptide bioconjugates. Chemmedchem. 1: 1268-74. PMID 17004283 DOI: 10.1002/cmdc.200600117  0.323
2006 Hamzavi R, Meyer C, Metzler-Nolte N. Synthesis of a C-linked glycosylated thymine-based PNA monomer and its incorporation into a PNA oligomer. Organic & Biomolecular Chemistry. 4: 3648-51. PMID 16990940 DOI: 10.1039/B607463D  0.323
2006 Kirin SI, Kraatz HB, Metzler-Nolte N. Systematizing structural motifs and nomenclature in 1,n'-disubstituted ferrocene peptides. Chemical Society Reviews. 35: 348-54. PMID 16565751 DOI: 10.1039/B511332F  0.379
2006 Kersebohm T, Kirin SI, Metzler-Nolte N. Insertion of an internal dipeptide into PNA oligomers: thermal melting studies and further functionalization. Bioorganic & Medicinal Chemistry Letters. 16: 2964-8. PMID 16546386 DOI: 10.1016/J.Bmcl.2006.02.071  0.353
2006 Hoffmanns U, Metzler-Nolte N. Use of the Sonogashira coupling reaction for the "two-step" labeling of phenylalanine peptide side chains with organometallic compounds. Bioconjugate Chemistry. 17: 204-13. PMID 16417270 DOI: 10.1021/Bc050259C  0.433
2006 Jios JL, Kirin SI, Weyhermüller T, Metzler-Nolte N, Della Védova CO. Synthesis, structural and spectroscopic study of aromatic thioester compounds Journal of Molecular Structure. 825: 53-59. DOI: 10.1016/J.Molstruc.2006.04.013  0.332
2006 Kirin SI, Schatzschneider U, de Hatten X, Weyhermüller T, Metzler-Nolte N. 1,n′-Disubstituted ferrocenoyl amino acids and dipeptides: Conformational analysis by CD spectroscopy, X-ray crystallography, and DFT calculations Journal of Organometallic Chemistry. 691: 3451-3457. DOI: 10.1016/J.Jorganchem.2006.04.025  0.327
2006 Barišić L, Rapić V, Metzler-Nolte N. Incorporation of the unnatural organometallic amino acid 1′-aminoferrocene-1-carboxylic acid (Fca) into oligopeptides by a combination of Fmoc and Boc solid-phase synthetic methods European Journal of Inorganic Chemistry. 4019-4021. DOI: 10.1002/Ejic.200600534  0.401
2005 Kirin SI, Dübon P, Weyhermüller T, Bill E, Metzler-Nolte N. Amino acid and peptide bioconjugates of copper(II) and zinc(II) complexes with a modified N,N-bis(2-picolyl)amine ligand. Inorganic Chemistry. 44: 5405-15. PMID 16022539 DOI: 10.1021/Ic048343B  0.383
2005 Noor F, Wüstholz A, Kinscherf R, Metzler-Nolte N. A cobaltocenium-peptide bioconjugate shows enhanced cellular uptake and directed nuclear delivery. Angewandte Chemie (International Ed. in English). 44: 2429-32. PMID 15747385 DOI: 10.1002/Anie.200462519  0.338
2005 Kirin SI, Wissenbach D, Metzler-Nolte N. Unsymmetrical 1,n′-disubstituted ferrocenoyl peptides: Convenient one pot synthesis and solution structures by CD and NMR spectroscopy New Journal of Chemistry. 29: 1168-1173. DOI: 10.1039/B504187B  0.388
2005 Chantson JT, Falzacappa MVV, Crovella S, Metzler-Nolte N. Antibacterial activities of ferrocenoyl- and cobaltocenium-peptide bioconjugates Journal of Organometallic Chemistry. 690: 4564-4572. DOI: 10.1016/J.Jorganchem.2005.07.007  0.393
2005 Maurer A, Kraatz HB, Metzler-Nolte N. Synthesis and electrochemical characterization of metallocene - PNA oligomers European Journal of Inorganic Chemistry. 3207-3210. DOI: 10.1002/Ejic.200500316  0.326
2004 van Staveren DR, Mundwiler S, Hoffmanns U, Pak JK, Spingler B, Metzler-Nolte N, Alberto R. Conjugation of a novel histidine derivative to biomolecules and labelling with [99mTc(OH2)3(CO)3]+. Organic & Biomolecular Chemistry. 2: 2593-603. PMID 15351823 DOI: 10.1039/B405575F  0.393
2004 Barisić L, Dropucić M, Rapić V, Pritzkow H, Kirin SI, Metzler-Nolte N. The first oligopeptide derivative of 1'-aminoferrocene-1-carboxylic acid shows helical chirality with antiparallel strands. Chemical Communications (Cambridge, England). 2004-5. PMID 15340643 DOI: 10.1039/B407771G  0.337
2004 Hatten XD, Weyhermüller T, Metzler-Nolte N. Ferrocenoyl peptides with sulfur-containing side chains: Synthesis, solid state and solution structures Journal of Organometallic Chemistry. 689: 4856-4867. DOI: 10.1016/J.Jorganchem.2004.10.002  0.413
2004 Hamzavi R, Happ T, Weitershaus K, Metzler-Nolte N. The use of 3,3-bis(2-imidazolyl) propionic acid (bip-OH) as a new chelating ligand for Re(CO) 3 and Ru complexes: Formation of organometallic PNA oligomers with (bip)Re(CO) 3 and their interaction with complementary DNA Journal of Organometallic Chemistry. 689: 4745-4750. DOI: 10.1016/J.Jorganchem.2004.09.009  0.414
2003 Van Staveren DR, Weyhermüller T, Metzler-Nolte N. Organometallic β-turn mimetics. A structural and spectroscopic study of inter-strand hydrogen bonding in ferrocene and cobaltocenium conjugates of amino acids and dipeptides Dalton Transactions. 210-220. DOI: 10.1039/B208363A  0.354
2002 van Staveren DR, Metzler-Nolte N. Labelling of [Leu5]-enkephalin with organometallic Mo complexes by solid-phase synthesis. Chemical Communications (Cambridge, England). 1406-7. PMID 12125577 DOI: 10.1039/B203128K  0.317
2002 Van Staveren DR, Bothe E, Weyhermüller T, Metzler-Nolte N. Spectroscopic properties, electrochemistry, and reactivity of Mo0, MoI, and MoIIcomplexes with the [Mo(bpa)(CO)3] unit [bpa = bis(2-picolyl)aminel and their application for the labelling of peptides European Journal of Inorganic Chemistry. 1518-1529. DOI: 10.1002/1099-0682(200206)2002:6<1518::Aid-Ejic1518>3.0.Co;2-7  0.392
2001 Sehnert J, Hess A, Metzler-Nolte N. Solution phase peptide synthesis with ferrocenyl amino acid derivatives Journal of Organometallic Chemistry. 637: 349-355. DOI: 10.1016/S0022-328X(01)00933-0  0.436
2000 Hess A, Sehnert J, Weyhermüller T, Metzler-Nolte N. Chiral ferrocene amines derived from amino acids and peptides: synthesis, solution and X-ray crystal structures and electrochemical investigations. Inorganic Chemistry. 39: 5437-43. PMID 11154558 DOI: 10.1021/Ic000089+  0.461
2000 Van Staveren DR, Weyhermüller T, Metzler-Nolte N. The Mo(η-allyl)(CO)2 moiety as a robust marker group in bioorganometallic chemistry. Unusual crystal structure of the phenylalanine derivative Mo(C5H4-CO-Phe-OMe)(η-allyl)(CO)2 Organometallics. 19: 3730-3735. DOI: 10.1021/Om0003483  0.345
2000 Brosch O, Weyhermüller T, Metzler-Nolte N. A Two‐Step Palladium‐Catalyzed Coupling Scheme for the Synthesis of Ferrocene‐Labeled Amino Acids European Journal of Inorganic Chemistry. 2000: 323-330. DOI: 10.1002/(Sici)1099-0682(200002)2000:2<323::Aid-Ejic323>3.0.Co;2-U  0.428
1999 Hess A, Metzler-Nolte N. Transition metal labels on peptide nucleic acid (PNA) monomers Chemical Communications. 885-886. DOI: 10.1039/A901561B  0.381
1999 Brosch O, Weyhermüller T, Metzler-Nolte N. Synthesis of alkynyl amino acids and peptides and their palladium-catalyzed coupling to ferrocene Inorganic Chemistry. 38: 5308-5313. DOI: 10.1021/Ic990256+  0.375
1999 Hess A, Brosch O, Weyhermüller T, Metzler-Nolte N. Synthesis of organometallic amines and their coupling to the C-terminus of amino acids and peptides Journal of Organometallic Chemistry. 589: 75-84. DOI: 10.1016/S0022-328X(99)00304-6  0.469
1998 Jüstel T, Bendix J, Metzler-Nolte N, Weyhermüller T, Nuber B, Wieghardt K. Ruthenium Complexes Containing "Noninnocent" o-Benzoquinone Diimine/o-Phenylenediamide(2-) Ligands. Synthesis and Crystal Structure of the Nitrido-Bridged Complex [{LRu(o-C(6)H(4)(NH)(2))}(2)(&mgr;-N)](PF(6))(2).3CH(3)CN.C(6)H(5)CH(3). Inorganic Chemistry. 37: 35-43. PMID 11670257 DOI: 10.1021/Ic970850O  0.3
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