Thomas C. Sudhof - Publications

Affiliations: 
Molecular and Cellular Physiology Stanford University, Palo Alto, CA 
 Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States 
 University Of Texas Sw Med Ctr/dallas 
Area:
Synapse
Website:
http://www.hhmi.org/scientists/thomas-c-sudhof

347 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 De Filippis L, Südhof TC, Pang ZP. Harness the power of endogenous neural stem cells by biomaterials to treat spinal cord injury. Science China. Life Sciences. 58: 1167-8. PMID 26481248 DOI: 10.1007/s11427-015-4943-z  0.96
2015 Bacaj T, Wu D, Burré J, Malenka RC, Liu X, Südhof TC. Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles. Plos Biology. 13: e1002267. PMID 26437117 DOI: 10.1371/journal.pbio.1002267  1
2015 Acuna C, Liu X, Gonzalez A, Südhof TC. RIM-BPs Mediate Tight Coupling of Action Potentials to Ca(2+)-Triggered Neurotransmitter Release. Neuron. 87: 1234-47. PMID 26402606 DOI: 10.1016/j.neuron.2015.08.027  1
2015 Yang X, Pei J, Kaeser-Woo YJ, Bacaj T, Grishin NV, Südhof TC. Evolutionary conservation of complexins: from choanoflagellates to mice. Embo Reports. 16: 1308-17. PMID 26338476 DOI: 10.15252/embr.201540305  0.96
2015 Zhang B, Chen LY, Liu X, Maxeiner S, Lee SJ, Gokce O, Südhof TC. Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses. Neuron. 87: 781-96. PMID 26291161 DOI: 10.1016/j.neuron.2015.07.020  1
2015 Liu Y, Li H, Sugiura Y, Han W, Gallardo G, Khvotchev M, Zhang Y, Kavalali ET, Südhof TC, Lin W. Ubiquitin-Synaptobrevin Fusion Protein Causes Degeneration of Presynaptic Motor Terminals in Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11514-31. PMID 26290230 DOI: 10.1523/JNEUROSCI.5288-14.2015  1
2015 Patzke C, Han Y, Covy J, Yi F, Maxeiner S, Wernig M, Südhof TC. Analysis of conditional heterozygous STXBP1 mutations in human neurons. The Journal of Clinical Investigation. 125: 3560-71. PMID 26280581 DOI: 10.1172/JCI78612  1
2015 Zhou Q, Lai Y, Bacaj T, Zhao M, Lyubimov AY, Uervirojnangkoorn M, Zeldin OB, Brewster AS, Sauter NK, Cohen AE, Soltis SM, Alonso-Mori R, Chollet M, Lemke HT, Pfuetzner RA, et al. Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis. Nature. 525: 62-7. PMID 26280336 DOI: 10.1038/nature14975  0.92
2015 Pak C, Danko T, Zhang Y, Aoto J, Anderson G, Maxeiner S, Yi F, Wernig M, Südhof TC. Human Neuropsychiatric Disease Modeling using Conditional Deletion Reveals Synaptic Transmission Defects Caused by Heterozygous Mutations in NRXN1. Cell Stem Cell. 17: 316-28. PMID 26279266 DOI: 10.1016/j.stem.2015.07.017  1
2015 Luo F, Bacaj T, Südhof TC. Synaptotagmin-7 Is Essential for Ca2+-Triggered Delayed Asynchronous Release But Not for Ca2+-Dependent Vesicle Priming in Retinal Ribbon Synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11024-33. PMID 26245964 DOI: 10.1523/JNEUROSCI.0759-15.2015  0.92
2015 Lu YC, Nazarko OV, Sando R, Salzman GS, Südhof TC, Araç D. Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion. Structure (London, England : 1993). 23: 1678-91. PMID 26235030 DOI: 10.1016/j.str.2015.06.024  0.8
2015 Wu B, Wei S, Petersen N, Ali Y, Wang X, Bacaj T, Rorsman P, Hong W, Südhof TC, Han W. Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 9996-10001. PMID 26216970 DOI: 10.1073/pnas.1513004112  1
2015 Anderson GR, Aoto J, Tabuchi K, Földy C, Covy J, Yee AX, Wu D, Lee SJ, Chen L, Malenka RC, Südhof TC. β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling. Cell. 162: 593-606. PMID 26213384 DOI: 10.1016/j.cell.2015.06.056  1
2015 Fuccillo MV, Földy C, Gökce Ö, Rothwell PE, Sun GL, Malenka RC, Südhof TC. Single-Cell mRNA Profiling Reveals Cell-Type-Specific Expression of Neurexin Isoforms. Neuron. 87: 326-40. PMID 26182417 DOI: 10.1016/j.neuron.2015.06.028  1
2015 Liang J, Xu W, Hsu YT, Yee AX, Chen L, Südhof TC. Conditional knockout of Nlgn2 in the adult medial prefrontal cortex (mPFC) induces delayed loss of inhibitory synapses. Molecular Psychiatry. 20: 793. PMID 26098222 DOI: 10.1038/mp.2015.82  0.96
2015 Brewer KD, Bacaj T, Cavalli A, Camilloni C, Swarbrick JD, Liu J, Zhou A, Zhou P, Barlow N, Xu J, Seven AB, Prinslow EA, Voleti R, Häussinger D, Bonvin AM, et al. Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution. Nature Structural & Molecular Biology. 22: 555-64. PMID 26030874 DOI: 10.1038/nsmb.3035  0.92
2015 Aoto J, Földy C, Ilcus SM, Tabuchi K, Südhof TC. Distinct circuit-dependent functions of presynaptic neurexin-3 at GABAergic and glutamatergic synapses. Nature Neuroscience. 18: 997-1007. PMID 26030848 DOI: 10.1038/nn.4037  1
2015 Bacaj T, Ahmad M, Jurado S, Malenka RC, Südhof TC. Synaptic Function of Rab11Fip5: Selective Requirement for Hippocampal Long-Term Depression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 7460-74. PMID 25972173 DOI: 10.1523/JNEUROSCI.1581-14.2015  1
2015 Arendt KL, Zhang Y, Jurado S, Malenka RC, Südhof TC, Chen L. Retinoic Acid and LTP Recruit Postsynaptic AMPA Receptors Using Distinct SNARE-Dependent Mechanisms. Neuron. 86: 442-56. PMID 25843403 DOI: 10.1016/j.neuron.2015.03.009  1
2015 Burré J, Sharma M, Südhof TC. Definition of a molecular pathway mediating α-synuclein neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5221-32. PMID 25834048 DOI: 10.1523/JNEUROSCI.4650-14.2015  1
2015 Liang J, Xu W, Hsu YT, Yee AX, Chen L, Südhof TC. Conditional neuroligin-2 knockout in adult medial prefrontal cortex links chronic changes in synaptic inhibition to cognitive impairments. Molecular Psychiatry. 20: 850-9. PMID 25824299 DOI: 10.1038/mp.2015.31  1
2015 Chanda S, Aoto J, Lee SJ, Wernig M, Südhof TC. Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor trafficking. Molecular Psychiatry. PMID 25778475 DOI: 10.1038/mp.2015.20  1
2015 Ressl S, Vu BK, Vivona S, Martinelli DC, Südhof TC, Brunger AT. Structures of C1q-like proteins reveal unique features among the C1q/TNF superfamily. Structure (London, England : 1993). 23: 688-99. PMID 25752542 DOI: 10.1016/j.str.2015.01.019  0.8
2015 Han Y, Babai N, Kaeser P, Südhof TC, Schneggenburger R. RIM1 and RIM2 redundantly determine Ca2+ channel density and readily releasable pool size at a large hindbrain synapse. Journal of Neurophysiology. 113: 255-63. PMID 25343783 DOI: 10.1152/jn.00488.2014  0.96
2014 Tsetsenis T, Boucard AA, Araç D, Brunger AT, Südhof TC. Direct visualization of trans-synaptic neurexin-neuroligin interactions during synapse formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15083-96. PMID 25378172 DOI: 10.1523/JNEUROSCI.0348-14.2014  0.84
2014 Imig C, Min SW, Krinner S, Arancillo M, Rosenmund C, Südhof TC, Rhee J, Brose N, Cooper BH. The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones. Neuron. 84: 416-31. PMID 25374362 DOI: 10.1016/j.neuron.2014.10.009  1
2014 Chanda S, Ang CE, Davila J, Pak C, Mall M, Lee QY, Ahlenius H, Jung SW, Südhof TC, Wernig M. Generation of induced neuronal cells by the single reprogramming factor ASCL1. Stem Cell Reports. 3: 282-96. PMID 25254342 DOI: 10.1016/j.stemcr.2014.05.020  1
2014 Burré J, Sharma M, Südhof TC. α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation. Proceedings of the National Academy of Sciences of the United States of America. 111: E4274-83. PMID 25246573 DOI: 10.1073/pnas.1416598111  1
2014 Liu C, Bickford LS, Held RG, Nyitrai H, Südhof TC, Kaeser PS. The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12289-303. PMID 25209271 DOI: 10.1523/JNEUROSCI.0999-14.2014  1
2014 Rothwell PE, Fuccillo MV, Maxeiner S, Hayton SJ, Gokce O, Lim BK, Fowler SC, Malenka RC, Südhof TC. Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors. Cell. 158: 198-212. PMID 24995986 DOI: 10.1016/j.cell.2014.04.045  1
2014 Acuna C, Guo Q, Burré J, Sharma M, Sun J, Südhof TC. Microsecond dissection of neurotransmitter release: SNARE-complex assembly dictates speed and Ca²⁺ sensitivity. Neuron. 82: 1088-100. PMID 24908488 DOI: 10.1016/j.neuron.2014.04.020  1
2014 Lee SH, Sharma M, Südhof TC, Shen J. Synaptic function of nicastrin in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 111: 8973-8. PMID 24889619 DOI: 10.1073/pnas.1408554111  1
2014 Treutlein B, Gokce O, Quake SR, Südhof TC. Cartography of neurexin alternative splicing mapped by single-molecule long-read mRNA sequencing. Proceedings of the National Academy of Sciences of the United States of America. 111: E1291-9. PMID 24639501 DOI: 10.1073/pnas.1403244111  0.96
2014 Um JW, Pramanik G, Ko JS, Song MY, Lee D, Kim H, Park KS, Südhof TC, Tabuchi K, Ko J. Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Cell Reports. 6: 1096-109. PMID 24613359 DOI: 10.1016/j.celrep.2014.02.010  1
2014 Xu J, Bacaj T, Zhou A, Tomchick DR, Südhof TC, Rizo J. Structure and Ca²⁺-binding properties of the tandem C₂ domains of E-Syt2. Structure (London, England : 1993). 22: 269-80. PMID 24373768 DOI: 10.1016/j.str.2013.11.011  0.92
2014 Boucard AA, Maxeiner S, Südhof TC. Latrophilins function as heterophilic cell-adhesion molecules by binding to teneurins: regulation by alternative splicing. The Journal of Biological Chemistry. 289: 387-402. PMID 24273166 DOI: 10.1074/jbc.M113.504779  0.96
2013 Yang X, Cao P, Südhof TC. Deconstructing complexin function in activating and clamping Ca2+-triggered exocytosis by comparing knockout and knockdown phenotypes. Proceedings of the National Academy of Sciences of the United States of America. 110: 20777-82. PMID 24297916 DOI: 10.1073/pnas.1321367110  0.96
2013 Bacaj T, Wu D, Yang X, Morishita W, Zhou P, Xu W, Malenka RC, Südhof TC. Synaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter release. Neuron. 80: 947-59. PMID 24267651 DOI: 10.1016/j.neuron.2013.10.026  1
2013 Wapinski OL, Vierbuchen T, Qu K, Lee QY, Chanda S, Fuentes DR, Giresi PG, Ng YH, Marro S, Neff NF, Drechsel D, Martynoga B, Castro DS, Webb AE, Südhof TC, et al. Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell. 155: 621-35. PMID 24243019 DOI: 10.1016/j.cell.2013.09.028  1
2013 Arancillo M, Min SW, Gerber S, Münster-Wandowski A, Wu YJ, Herman M, Trimbuch T, Rah JC, Ahnert-Hilger G, Riedel D, Südhof TC, Rosenmund C. Titration of Syntaxin1 in mammalian synapses reveals multiple roles in vesicle docking, priming, and release probability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16698-714. PMID 24133272 DOI: 10.1523/JNEUROSCI.0187-13.2013  1
2013 Zhou P, Bacaj T, Yang X, Pang ZP, Südhof TC. Lipid-anchored SNAREs lacking transmembrane regions fully support membrane fusion during neurotransmitter release. Neuron. 80: 470-83. PMID 24120845 DOI: 10.1016/j.neuron.2013.09.010  0.96
2013 Chanda S, Marro S, Wernig M, Südhof TC. Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation. Proceedings of the National Academy of Sciences of the United States of America. 110: 16622-7. PMID 24046374 DOI: 10.1073/pnas.1316240110  1
2013 Gokce O, Südhof TC. Membrane-tethered monomeric neurexin LNS-domain triggers synapse formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14617-28. PMID 24005312 DOI: 10.1523/JNEUROSCI.1232-13.2013  0.96
2013 Soler-Llavina GJ, Arstikaitis P, Morishita W, Ahmad M, Südhof TC, Malenka RC. Leucine-rich repeat transmembrane proteins are essential for maintenance of long-term potentiation. Neuron. 79: 439-46. PMID 23931994 DOI: 10.1016/j.neuron.2013.06.007  1
2013 Aoto J, Martinelli DC, Malenka RC, Tabuchi K, Südhof TC. Presynaptic neurexin-3 alternative splicing trans-synaptically controls postsynaptic AMPA receptor trafficking. Cell. 154: 75-88. PMID 23827676 DOI: 10.1016/j.cell.2013.05.060  1
2013 Pertsinidis A, Mukherjee K, Sharma M, Pang ZP, Park SR, Zhang Y, Brunger AT, Südhof TC, Chu S. Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ. Proceedings of the National Academy of Sciences of the United States of America. 110: E2812-20. PMID 23821748 DOI: 10.1073/pnas.1310654110  1
2013 Burré J, Vivona S, Diao J, Sharma M, Brunger AT, Südhof TC. Properties of native brain α-synuclein. Nature. 498: E4-6; discussion E6-. PMID 23765500 DOI: 10.1038/nature12125  1
2013 Zhang Y, Pak C, Han Y, Ahlenius H, Zhang Z, Chanda S, Marro S, Patzke C, Acuna C, Covy J, Xu W, Yang N, Danko T, Chen L, Wernig M, et al. Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron. 78: 785-98. PMID 23764284 DOI: 10.1016/j.neuron.2013.05.029  1
2013 Kaeser-Woo YJ, Younts TJ, Yang X, Zhou P, Wu D, Castillo PE, Südhof TC. Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9769-80. PMID 23739973 DOI: 10.1523/JNEUROSCI.5814-12.2013  0.96
2013 Diao J, Burré J, Vivona S, Cipriano DJ, Sharma M, Kyoung M, Südhof TC, Brunger AT. Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2. Elife. 2: e00592. PMID 23638301 DOI: 10.7554/eLife.00592  1
2013 Földy C, Malenka RC, Südhof TC. Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signaling. Neuron. 78: 498-509. PMID 23583622 DOI: 10.1016/j.neuron.2013.02.036  1
2013 Davila J, Chanda S, Ang CE, Südhof TC, Wernig M. Acute reduction in oxygen tension enhances the induction of neurons from human fibroblasts. Journal of Neuroscience Methods. 216: 104-9. PMID 23562599 DOI: 10.1016/j.jneumeth.2013.03.020  1
2013 Xu W, Südhof TC. A neural circuit for memory specificity and generalization. Science (New York, N.Y.). 339: 1290-5. PMID 23493706 DOI: 10.1126/science.1229534  1
2013 Jurado S, Goswami D, Zhang Y, Molina AJ, Südhof TC, Malenka RC. LTP requires a unique postsynaptic SNARE fusion machinery. Neuron. 77: 542-58. PMID 23395379 DOI: 10.1016/j.neuron.2012.11.029  1
2013 Cao P, Yang X, Südhof TC. Complexin activates exocytosis of distinct secretory vesicles controlled by different synaptotagmins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1714-27. PMID 23345244 DOI: 10.1523/JNEUROSCI.4087-12.2013  0.96
2013 Lee K, Kim Y, Lee SJ, Qiang Y, Lee D, Lee HW, Kim H, Je HS, Südhof TC, Ko J. MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development. Proceedings of the National Academy of Sciences of the United States of America. 110: 336-41. PMID 23248271 DOI: 10.1073/pnas.1219987110  1
2013 Zhou P, Pang ZP, Yang X, Zhang Y, Rosenmund C, Bacaj T, Südhof TC. Syntaxin-1 N-peptide and Habc-domain perform distinct essential functions in synaptic vesicle fusion. The Embo Journal. 32: 159-71. PMID 23188083 DOI: 10.1038/emboj.2012.307  1
2012 Burré J, Sharma M, Südhof TC. Systematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15227-42. PMID 23100443 DOI: 10.1523/JNEUROSCI.3545-12.2012  1
2012 Anderson GR, Galfin T, Xu W, Aoto J, Malenka RC, Südhof TC. Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development. Proceedings of the National Academy of Sciences of the United States of America. 109: 18120-5. PMID 23074245 DOI: 10.1073/pnas.1216398109  1
2012 Rizo J, Südhof TC. The membrane fusion enigma: SNAREs, Sec1/Munc18 proteins, and their accomplices--guilty as charged? Annual Review of Cell and Developmental Biology. 28: 279-308. PMID 23057743 DOI: 10.1146/annurev-cellbio-101011-155818  0.88
2012 Sharma M, Burré J, Südhof TC. Proteasome inhibition alleviates SNARE-dependent neurodegeneration. Science Translational Medicine. 4: 147ra113. PMID 22896677 DOI: 10.1126/scitranslmed.3004028  1
2012 Yang SN, Shi Y, Yang G, Li Y, Yu L, Shin OH, Bacaj T, Südhof TC, Yu J, Berggren PO. Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron. Proceedings of the National Academy of Sciences of the United States of America. 109: 12183-8. PMID 22778403 DOI: 10.1073/pnas.1115070109  1
2012 Kaeser PS, Deng L, Fan M, Südhof TC. RIM genes differentially contribute to organizing presynaptic release sites. Proceedings of the National Academy of Sciences of the United States of America. 109: 11830-5. PMID 22753485 DOI: 10.1073/pnas.1209318109  1
2012 Narboux-Nême N, Evrard A, Ferezou I, Erzurumlu RS, Kaeser PS, Lainé J, Rossier J, Ropert N, Südhof TC, Gaspar P. Neurotransmitter release at the thalamocortical synapse instructs barrel formation but not axon patterning in the somatosensory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6183-96. PMID 22553025 DOI: 10.1523/JNEUROSCI.0343-12.2012  1
2012 Sheng M, Sabatini BL, Südhof TC. Synapses and Alzheimer's disease. Cold Spring Harbor Perspectives in Biology. 4. PMID 22491782 DOI: 10.1101/cshperspect.a005777  0.44
2012 Xu W, Morishita W, Buckmaster PS, Pang ZP, Malenka RC, Südhof TC. Distinct neuronal coding schemes in memory revealed by selective erasure of fast synchronous synaptic transmission. Neuron. 73: 990-1001. PMID 22405208 DOI: 10.1016/j.neuron.2011.12.036  1
2012 Kaeser-Woo YJ, Yang X, Südhof TC. C-terminal complexin sequence is selectively required for clamping and priming but not for Ca2+ triggering of synaptic exocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2877-85. PMID 22357870 DOI: 10.1523/JNEUROSCI.3360-11.2012  0.96
2012 Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT. A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. The Embo Journal. 31: 1364-78. PMID 22333914 DOI: 10.1038/emboj.2012.26  0.84
2012 Lujan E, Chanda S, Ahlenius H, Südhof TC, Wernig M. Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 2527-32. PMID 22308465 DOI: 10.1073/pnas.1121003109  1
2012 Ahmad M, Polepalli JS, Goswami D, Yang X, Kaeser-Woo YJ, Südhof TC, Malenka RC. Postsynaptic complexin controls AMPA receptor exocytosis during LTP. Neuron. 73: 260-7. PMID 22284181 DOI: 10.1016/j.neuron.2011.11.020  1
2012 Missler M, Südhof TC, Biederer T. Synaptic cell adhesion. Cold Spring Harbor Perspectives in Biology. 4: a005694. PMID 22278667 DOI: 10.1101/cshperspect.a005694  1
2012 Boucard AA, Ko J, Südhof TC. High affinity neurexin binding to cell adhesion G-protein-coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex. The Journal of Biological Chemistry. 287: 9399-413. PMID 22262843 DOI: 10.1074/jbc.M111.318659  1
2012 Sharma M, Burré J, Bronk P, Zhang Y, Xu W, Südhof TC. CSPα knockout causes neurodegeneration by impairing SNAP-25 function. The Embo Journal. 31: 829-41. PMID 22187053 DOI: 10.1038/emboj.2011.467  1
2012 Haws ME, Kaeser PS, Jarvis DL, Südhof TC, Powell CM. Region-specific deletions of RIM1 reproduce a subset of global RIM1α(-/-) phenotypes. Genes, Brain, and Behavior. 11: 201-13. PMID 22103334 DOI: 10.1111/j.1601-183X.2011.00755.x  1
2011 Citri A, Pang ZP, Südhof TC, Wernig M, Malenka RC. Comprehensive qPCR profiling of gene expression in single neuronal cells. Nature Protocols. 7: 118-27. PMID 22193304 DOI: 10.1038/nprot.2011.430  1
2011 Yang N, Ng YH, Pang ZP, Südhof TC, Wernig M. Induced neuronal cells: how to make and define a neuron. Cell Stem Cell. 9: 517-25. PMID 22136927 DOI: 10.1016/j.stem.2011.11.015  1
2011 Südhof TC, Rizo J. Synaptic vesicle exocytosis. Cold Spring Harbor Perspectives in Biology. 3. PMID 22026965 DOI: 10.1101/cshperspect.a005637  0.88
2011 Marro S, Pang ZP, Yang N, Tsai MC, Qu K, Chang HY, Südhof TC, Wernig M. Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Cell Stem Cell. 9: 374-82. PMID 21962918 DOI: 10.1016/j.stem.2011.09.002  1
2011 Soler-Llavina GJ, Fuccillo MV, Ko J, Südhof TC, Malenka RC. The neurexin ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent and divergent synaptic functions in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: 16502-9. PMID 21953696 DOI: 10.1073/pnas.1114028108  1
2011 Tsetsenis T, Younts TJ, Chiu CQ, Kaeser PS, Castillo PE, Südhof TC. Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning. Proceedings of the National Academy of Sciences of the United States of America. 108: 14300-5. PMID 21844341 DOI: 10.1073/pnas.1112237108  1
2011 Etherton M, Földy C, Sharma M, Tabuchi K, Liu X, Shamloo M, Malenka RC, Südhof TC. Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function. Proceedings of the National Academy of Sciences of the United States of America. 108: 13764-9. PMID 21808020 DOI: 10.1073/pnas.1111093108  1
2011 Ko J, Soler-Llavina GJ, Fuccillo MV, Malenka RC, Südhof TC. Neuroligins/LRRTMs prevent activity- and Ca2+/calmodulin-dependent synapse elimination in cultured neurons. The Journal of Cell Biology. 194: 323-34. PMID 21788371 DOI: 10.1083/jcb.201101072  1
2011 Etherton MR, Tabuchi K, Sharma M, Ko J, Südhof TC. An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus. The Embo Journal. 30: 2908-19. PMID 21642956 DOI: 10.1038/emboj.2011.182  1
2011 Pang ZP, Yang N, Vierbuchen T, Ostermeier A, Fuentes DR, Yang TQ, Citri A, Sebastiano V, Marro S, Südhof TC, Wernig M. Induction of human neuronal cells by defined transcription factors. Nature. 476: 220-3. PMID 21617644 DOI: 10.1038/nature10202  1
2011 Pang ZP, Bacaj T, Yang X, Zhou P, Xu W, Südhof TC. Doc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanism. Neuron. 70: 244-51. PMID 21521611 DOI: 10.1016/j.neuron.2011.03.011  1
2011 Cao P, Maximov A, Südhof TC. Activity-dependent IGF-1 exocytosis is controlled by the Ca(2+)-sensor synaptotagmin-10. Cell. 145: 300-11. PMID 21496647 DOI: 10.1016/j.cell.2011.03.034  0.96
2011 Martinelli DC, Südhof TC. Cerebellins meet neurexins (Commentary on Matsuda & Yuzaki). The European Journal of Neuroscience. 33: 1445-6. PMID 21496123 DOI: 10.1111/j.1460-9568.2011.07665.x  0.8
2011 Bolliger MF, Martinelli DC, Südhof TC. The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins. Proceedings of the National Academy of Sciences of the United States of America. 108: 2534-9. PMID 21262840 DOI: 10.1073/pnas.1019577108  0.8
2011 Deng L, Kaeser PS, Xu W, Südhof TC. RIM proteins activate vesicle priming by reversing autoinhibitory homodimerization of Munc13. Neuron. 69: 317-31. PMID 21262469 DOI: 10.1016/j.neuron.2011.01.005  1
2011 Han Y, Kaeser PS, Südhof TC, Schneggenburger R. RIM determines Ca²+ channel density and vesicle docking at the presynaptic active zone. Neuron. 69: 304-16. PMID 21262468 DOI: 10.1016/j.neuron.2010.12.014  1
2011 Kaeser PS, Deng L, Wang Y, Dulubova I, Liu X, Rizo J, Südhof TC. RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction. Cell. 144: 282-95. PMID 21241895 DOI: 10.1016/j.cell.2010.12.029  1
2011 Sharma M, Burré J, Südhof TC. CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity. Nature Cell Biology. 13: 30-9. PMID 21151134 DOI: 10.1038/ncb2131  1
2011 Gustavsson N, Seah T, Lao Y, Radda GK, Südhof TC, Han W. Delayed onset of hyperglycaemia in a mouse model with impaired glucagon secretion demonstrates that dysregulated glucagon secretion promotes hyperglycaemia and type 2 diabetes. Diabetologia. 54: 415-22. PMID 20978738 DOI: 10.1007/s00125-010-1950-2  0.92
2010 Bacaj T, Pang ZP, Südhof TC. Testing the SNARE/SM protein model of membrane fusion. Proceedings of the National Academy of Sciences of the United States of America. 107: 22365-6. PMID 21169506 DOI: 10.1073/pnas.1017268108  0.96
2010 Yang X, Kaeser-Woo YJ, Pang ZP, Xu W, Südhof TC. Complexin clamps asynchronous release by blocking a secondary Ca(2+) sensor via its accessory α helix. Neuron. 68: 907-20. PMID 21145004 DOI: 10.1016/j.neuron.2010.11.001  1
2010 Robbins EM, Krupp AJ, Perez de Arce K, Ghosh AK, Fogel AI, Boucard A, Südhof TC, Stein V, Biederer T. SynCAM 1 adhesion dynamically regulates synapse number and impacts plasticity and learning. Neuron. 68: 894-906. PMID 21145003 DOI: 10.1016/j.neuron.2010.11.003  1
2010 Gustavsson N, Wang X, Wang Y, Seah T, Xu J, Radda GK, Südhof TC, Han W. Neuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretion. Plos One. 5: e15414. PMID 21085706 DOI: 10.1371/journal.pone.0015414  1
2010 Segovia M, Alés E, Montes MA, Bonifas I, Jemal I, Lindau M, Maximov A, Südhof TC, Alvarez de Toledo G. Push-and-pull regulation of the fusion pore by synaptotagmin-7. Proceedings of the National Academy of Sciences of the United States of America. 107: 19032-7. PMID 20956309 DOI: 10.1073/pnas.1014070107  0.88
2010 Li H, Wang B, Wang Z, Guo Q, Tabuchi K, Hammer RE, Südhof TC, Zheng H. Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP. Proceedings of the National Academy of Sciences of the United States of America. 107: 17362-7. PMID 20855613 DOI: 10.1073/pnas.1012568107  0.92
2010 Zhang D, Zhang C, Ho A, Kirkwood A, Südhof TC, Shen J. Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunction. Journal of Neurochemistry. 115: 1215-21. PMID 20854432 DOI: 10.1111/j.1471-4159.2010.07011.x  1
2010 Xue M, Craig TK, Shin OH, Li L, Brautigam CA, Tomchick DR, Südhof TC, Rosenmund C, Rizo J. Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7. Plos One. 5. PMID 20824061 DOI: 10.1371/journal.pone.0012544  1
2010 Burré J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Südhof TC. Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science (New York, N.Y.). 329: 1663-7. PMID 20798282 DOI: 10.1126/science.1195227  1
2010 Pang ZP, Xu W, Cao P, Südhof TC. Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons. The Journal of Biological Chemistry. 285: 33930-9. PMID 20729199 DOI: 10.1074/jbc.M110.150151  1
2010 Schonn JS, van Weering JR, Mohrmann R, Schlüter OM, Südhof TC, de Wit H, Verhage M, Sørensen JB. Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells. Traffic (Copenhagen, Denmark). 11: 1415-28. PMID 20716109 DOI: 10.1111/j.1600-0854.2010.01107.x  1
2010 Li H, Wang Z, Wang B, Guo Q, Dolios G, Tabuchi K, Hammer RE, Südhof TC, Wang R, Zheng H. Genetic dissection of the amyloid precursor protein in developmental function and amyloid pathogenesis. The Journal of Biological Chemistry. 285: 30598-605. PMID 20693289 DOI: 10.1074/jbc.M110.137729  0.92
2010 Pang ZP, Südhof TC. Cell biology of Ca2+-triggered exocytosis. Current Opinion in Cell Biology. 22: 496-505. PMID 20561775 DOI: 10.1016/j.ceb.2010.05.001  0.96
2010 Zhang C, Atasoy D, Araç D, Yang X, Fucillo MV, Robison AJ, Ko J, Brunger AT, Südhof TC. Neurexins physically and functionally interact with GABA(A) receptors. Neuron. 66: 403-16. PMID 20471353 DOI: 10.1016/j.neuron.2010.04.008  1
2010 Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, et al. Climate change and the integrity of science. Science (New York, N.Y.). 328: 689-90. PMID 20448167 DOI: 10.1126/science.328.5979.689  0.56
2010 Mukherjee K, Sharma M, Jahn R, Wahl MC, Südhof TC. Evolution of CASK into a Mg2+-sensitive kinase. Science Signaling. 3: ra33. PMID 20424264 DOI: 10.1126/scisignal.2000800  1
2010 Blundell J, Kaeser PS, Südhof TC, Powell CM. RIM1alpha and interacting proteins involved in presynaptic plasticity mediate prepulse inhibition and additional behaviors linked to schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5326-33. PMID 20392954 DOI: 10.1523/JNEUROSCI.0328-10.2010  1
2010 Mukherjee K, Yang X, Gerber SH, Kwon HB, Ho A, Castillo PE, Liu X, Südhof TC. Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis. Proceedings of the National Academy of Sciences of the United States of America. 107: 6504-9. PMID 20332206 DOI: 10.1073/pnas.1002307107  1
2010 Pang ZP, Cao P, Xu W, Südhof TC. Calmodulin controls synaptic strength via presynaptic activation of calmodulin kinase II. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4132-42. PMID 20237283 DOI: 10.1523/JNEUROSCI.3129-09.2010  1
2010 Shin OH, Lu J, Rhee JS, Tomchick DR, Pang ZP, Wojcik SM, Camacho-Perez M, Brose N, Machius M, Rizo J, Rosenmund C, Südhof TC. Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nature Structural & Molecular Biology. 17: 280-8. PMID 20154707 DOI: 10.1038/nsmb.1758  1
2010 Blundell J, Blaiss CA, Etherton MR, Espinosa F, Tabuchi K, Walz C, Bolliger MF, Südhof TC, Powell CM. Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2115-29. PMID 20147539 DOI: 10.1523/JNEUROSCI.4517-09.2010  0.92
2010 Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Südhof TC, Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature. 463: 1035-41. PMID 20107439 DOI: 10.1038/nature08797  1
2009 Ko J, Fuccillo MV, Malenka RC, Südhof TC. LRRTM2 functions as a neurexin ligand in promoting excitatory synapse formation. Neuron. 64: 791-8. PMID 20064387 DOI: 10.1016/j.neuron.2009.12.012  1
2009 Gibson JR, Huber KM, Südhof TC. Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 13883-97. PMID 19889999 DOI: 10.1523/JNEUROSCI.2457-09.2009  0.72
2009 Kaeser PS, Deng L, Chávez AE, Liu X, Castillo PE, Südhof TC. ELKS2alpha/CAST deletion selectively increases neurotransmitter release at inhibitory synapses. Neuron. 64: 227-39. PMID 19874790 DOI: 10.1016/j.neuron.2009.09.019  1
2009 Etherton MR, Blaiss CA, Powell CM, Südhof TC. Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments. Proceedings of the National Academy of Sciences of the United States of America. 106: 17998-8003. PMID 19822762 DOI: 10.1073/pnas.0910297106  0.92
2009 Shin OH, Xu J, Rizo J, Südhof TC. Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release. Proceedings of the National Academy of Sciences of the United States of America. 106: 16469-74. PMID 19805322 DOI: 10.1073/pnas.0908798106  1
2009 Ko J, Zhang C, Arac D, Boucard AA, Brunger AT, Südhof TC. Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation. The Embo Journal. 28: 3244-55. PMID 19730411 DOI: 10.1038/emboj.2009.249  1
2009 Zhang C, Milunsky JM, Newton S, Ko J, Zhao G, Maher TA, Tager-Flusberg H, Bolliger MF, Carter AS, Boucard AA, Powell CM, Südhof TC. A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10843-54. PMID 19726642 DOI: 10.1523/JNEUROSCI.1248-09.2009  1
2009 Zhang C, Wu B, Beglopoulos V, Wines-Samuelson M, Zhang D, Dragatsis I, Südhof TC, Shen J. Presenilins are essential for regulating neurotransmitter release. Nature. 460: 632-6. PMID 19641596 DOI: 10.1038/nature08177  0.92
2009 Deák F, Liu X, Khvotchev M, Li G, Kavalali ET, Sugita S, Südhof TC. Alpha-latrotoxin stimulates a novel pathway of Ca2+-dependent synaptic exocytosis independent of the classical synaptic fusion machinery. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8639-48. PMID 19587270 DOI: 10.1523/JNEUROSCI.0898-09.2009  1
2009 Tabuchi K, Chen G, Südhof TC, Shen J. Conditional forebrain inactivation of nicastrin causes progressive memory impairment and age-related neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7290-301. PMID 19494151 DOI: 10.1523/JNEUROSCI.1320-09.2009  0.92
2009 Xu J, Pang ZP, Shin OH, Südhof TC. Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous release. Nature Neuroscience. 12: 759-66. PMID 19412166 DOI: 10.1038/nn.2320  1
2009 Deák F, Xu Y, Chang WP, Dulubova I, Khvotchev M, Liu X, Südhof TC, Rizo J. Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming. The Journal of Cell Biology. 184: 751-64. PMID 19255244 DOI: 10.1083/jcb.200812026  1
2009 Chang WP, Südhof TC. SV2 renders primed synaptic vesicles competent for Ca2+ -induced exocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 883-97. PMID 19176798 DOI: 10.1523/JNEUROSCI.4521-08.2009  0.76
2009 Gustavsson N, Wei SH, Hoang DN, Lao Y, Zhang Q, Radda GK, Rorsman P, Südhof TC, Han W. Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas. The Journal of Physiology. 587: 1169-78. PMID 19171650 DOI: 10.1113/jphysiol.2008.168005  1
2009 Maximov A, Tang J, Yang X, Pang ZP, Südhof TC. Complexin controls the force transfer from SNARE complexes to membranes in fusion. Science (New York, N.Y.). 323: 516-21. PMID 19164751 DOI: 10.1126/science.1166505  0.96
2009 Blundell J, Tabuchi K, Bolliger MF, Blaiss CA, Brose N, Liu X, Südhof TC, Powell CM. Increased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2. Genes, Brain, and Behavior. 8: 114-26. PMID 19016888 DOI: 10.1111/j.1601-183X.2008.00455.x  1
2008 Ho A, Liu X, Südhof TC. Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14392-400. PMID 19118172 DOI: 10.1523/JNEUROSCI.2481-08.2008  1
2008 Kaeser PS, Kwon HB, Chiu CQ, Deng L, Castillo PE, Südhof TC. RIM1alpha and RIM1beta are synthesized from distinct promoters of the RIM1 gene to mediate differential but overlapping synaptic functions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13435-47. PMID 19074017 DOI: 10.1523/JNEUROSCI.3235-08.2008  1
2008 Südhof TC, Malenka RC. Understanding synapses: past, present, and future. Neuron. 60: 469-76. PMID 18995821 DOI: 10.1016/j.neuron.2008.10.011  1
2008 Kaeser PS, Kwon HB, Blundell J, Chevaleyre V, Morishita W, Malenka RC, Powell CM, Castillo PE, Südhof TC. RIM1alpha phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning. Proceedings of the National Academy of Sciences of the United States of America. 105: 14680-5. PMID 18799741 DOI: 10.1073/pnas.0806679105  1
2008 Gerber SH, Rah JC, Min SW, Liu X, de Wit H, Dulubova I, Meyer AC, Rizo J, Arancillo M, Hammer RE, Verhage M, Rosenmund C, Südhof TC. Conformational switch of syntaxin-1 controls synaptic vesicle fusion. Science (New York, N.Y.). 321: 1507-10. PMID 18703708 DOI: 10.1126/science.1163174  1
2008 Ruiz R, Casañas JJ, Südhof TC, Tabares L. Cysteine string protein-alpha is essential for the high calcium sensitivity of exocytosis in a vertebrate synapse. The European Journal of Neuroscience. 27: 3118-31. PMID 18598257 DOI: 10.1111/j.1460-9568.2008.06301.x  0.92
2008 Bolliger MF, Pei J, Maxeiner S, Boucard AA, Grishin NV, Südhof TC. Unusually rapid evolution of Neuroligin-4 in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 6421-6. PMID 18434543 DOI: 10.1073/pnas.0801383105  0.96
2008 Mukherjee K, Sharma M, Urlaub H, Bourenkov GP, Jahn R, Südhof TC, Wahl MC. CASK Functions as a Mg2+-independent neurexin kinase. Cell. 133: 328-39. PMID 18423203 DOI: 10.1016/j.cell.2008.02.036  1
2008 Gustavsson N, Lao Y, Maximov A, Chuang JC, Kostromina E, Repa JJ, Li C, Radda GK, Südhof TC, Han W. Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 3992-7. PMID 18308938 DOI: 10.1073/pnas.0711700105  1
2008 Maximov A, Lao Y, Li H, Chen X, Rizo J, Sørensen JB, Südhof TC. Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 3986-91. PMID 18308933 DOI: 10.1073/pnas.0712372105  0.88
2008 Schonn JS, Maximov A, Lao Y, Südhof TC, Sørensen JB. Synaptotagmin-1 and -7 are functionally overlapping Ca2+ sensors for exocytosis in adrenal chromaffin cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 3998-4003. PMID 18308932 DOI: 10.1073/pnas.0712373105  0.88
2008 Gallardo G, Schlüter OM, Südhof TC. A molecular pathway of neurodegeneration linking alpha-synuclein to ApoE and Abeta peptides. Nature Neuroscience. 11: 301-8. PMID 18297066 DOI: 10.1038/nn2058  1
2007 Araç D, Boucard AA, Ozkan E, Strop P, Newell E, Südhof TC, Brunger AT. Structures of neuroligin-1 and the neuroligin-1/neurexin-1 beta complex reveal specific protein-protein and protein-Ca2+ interactions. Neuron. 56: 992-1003. PMID 18093522 DOI: 10.1016/j.neuron.2007.12.002  0.84
2007 Sun J, Pang ZP, Qin D, Fahim AT, Adachi R, Südhof TC. A dual-Ca2+-sensor model for neurotransmitter release in a central synapse. Nature. 450: 676-82. PMID 18046404 DOI: 10.1038/nature06308  0.96
2007 Khvotchev M, Dulubova I, Sun J, Dai H, Rizo J, Südhof TC. Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12147-55. PMID 17989281 DOI: 10.1523/JNEUROSCI.3655-07.2007  0.88
2007 Tabuchi K, Blundell J, Etherton MR, Hammer RE, Liu X, Powell CM, Südhof TC. A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science (New York, N.Y.). 318: 71-6. PMID 17823315 DOI: 10.1126/science.1146221  1
2007 Wu H, Xu J, Pang ZP, Ge W, Kim KJ, Blanchi B, Chen C, Südhof TC, Sun YE. Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. Proceedings of the National Academy of Sciences of the United States of America. 104: 13821-6. PMID 17693548 DOI: 10.1073/pnas.0706199104  0.96
2007 Guan R, Dai H, Tomchick DR, Dulubova I, Machius M, Südhof TC, Rizo J. Crystal structure of the RIM1alpha C2B domain at 1.7 A resolution. Biochemistry. 46: 8988-98. PMID 17630786 DOI: 10.1021/bi700698a  0.88
2007 Chubykin AA, Atasoy D, Etherton MR, Brose N, Kavalali ET, Gibson JR, Südhof TC. Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2. Neuron. 54: 919-31. PMID 17582332 DOI: 10.1016/j.neuron.2007.05.029  1
2007 Bronk P, Deák F, Wilson MC, Liu X, Südhof TC, Kavalali ET. Differential effects of SNAP-25 deletion on Ca2+ -dependent and Ca2+ -independent neurotransmission. Journal of Neurophysiology. 98: 794-806. PMID 17553942 DOI: 10.1152/jn.00226.2007  1
2007 Chevaleyre V, Heifets BD, Kaeser PS, Südhof TC, Purpura DP, Castillo PE. Endocannabinoid-mediated long-term plasticity requires cAMP/PKA signaling and RIM1alpha. Neuron. 54: 801-12. PMID 17553427 DOI: 10.1016/j.neuron.2007.05.020  1
2007 Xu J, Mashimo T, Südhof TC. Synaptotagmin-1, -2, and -9: Ca(2+) sensors for fast release that specify distinct presynaptic properties in subsets of neurons. Neuron. 54: 567-81. PMID 17521570 DOI: 10.1016/j.neuron.2007.05.004  0.8
2007 Min SW, Chang WP, Südhof TC. E-Syts, a family of membranous Ca2+-sensor proteins with multiple C2 domains. Proceedings of the National Academy of Sciences of the United States of America. 104: 3823-8. PMID 17360437 DOI: 10.1073/pnas.0611725104  0.76
2007 Dudanova I, Tabuchi K, Rohlmann A, Südhof TC, Missler M. Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation. The Journal of Comparative Neurology. 502: 261-74. PMID 17347997 DOI: 10.1002/cne.21305  1
2007 Dulubova I, Khvotchev M, Liu S, Huryeva I, Südhof TC, Rizo J. Munc18-1 binds directly to the neuronal SNARE complex. Proceedings of the National Academy of Sciences of the United States of America. 104: 2697-702. PMID 17301226 DOI: 10.1073/pnas.0611318104  0.88
2007 Atasoy D, Schoch S, Ho A, Nadasy KA, Liu X, Zhang W, Mukherjee K, Nosyreva ED, Fernandez-Chacon R, Missler M, Kavalali ET, Südhof TC. Deletion of CASK in mice is lethal and impairs synaptic function. Proceedings of the National Academy of Sciences of the United States of America. 104: 2525-30. PMID 17287346 DOI: 10.1073/pnas.0611003104  1
2007 Maximov A, Shin OH, Liu X, Südhof TC. Synaptotagmin-12, a synaptic vesicle phosphoprotein that modulates spontaneous neurotransmitter release. The Journal of Cell Biology. 176: 113-24. PMID 17190793 DOI: 10.1083/jcb.200607021  1
2007 Maximov A, Pang ZP, Tervo DG, Südhof TC. Monitoring synaptic transmission in primary neuronal cultures using local extracellular stimulation. Journal of Neuroscience Methods. 161: 75-87. PMID 17118459 DOI: 10.1016/j.jneumeth.2006.10.009  0.96
2006 Pang ZP, Melicoff E, Padgett D, Liu Y, Teich AF, Dickey BF, Lin W, Adachi R, Südhof TC. Synaptotagmin-2 is essential for survival and contributes to Ca2+ triggering of neurotransmitter release in central and neuromuscular synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13493-504. PMID 17192432 DOI: 10.1523/JNEUROSCI.3519-06.2006  0.96
2006 Ho A, Morishita W, Atasoy D, Liu X, Tabuchi K, Hammer RE, Malenka RC, Südhof TC. Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13089-101. PMID 17167098 DOI: 10.1523/JNEUROSCI.2855-06.2006  1
2006 Juranek J, Mukherjee K, Rickmann M, Martens H, Calka J, Südhof TC, Jahn R. Differential expression of active zone proteins in neuromuscular junctions suggests functional diversification. The European Journal of Neuroscience. 24: 3043-52. PMID 17156365 DOI: 10.1111/j.1460-9568.2006.05183.x  0.96
2006 Pang ZP, Shin OH, Meyer AC, Rosenmund C, Südhof TC. A gain-of-function mutation in synaptotagmin-1 reveals a critical role of Ca2+-dependent soluble N-ethylmaleimide-sensitive factor attachment protein receptor complex binding in synaptic exocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12556-65. PMID 17135417 DOI: 10.1523/JNEUROSCI.3804-06.2006  1
2006 Schoch S, Mittelstaedt T, Kaeser PS, Padgett D, Feldmann N, Chevaleyre V, Castillo PE, Hammer RE, Han W, Schmitz F, Lin W, Südhof TC. Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release. The Embo Journal. 25: 5852-63. PMID 17124501 DOI: 10.1038/sj.emboj.7601425  1
2006 Comoletti D, Flynn RE, Boucard AA, Demeler B, Schirf V, Shi J, Jennings LL, Newlin HR, Südhof TC, Taylor P. Gene selection, alternative splicing, and post-translational processing regulate neuroligin selectivity for beta-neurexins. Biochemistry. 45: 12816-27. PMID 17042500 DOI: 10.1021/bi0614131  0.84
2006 Tang J, Maximov A, Shin OH, Dai H, Rizo J, Südhof TC. A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis. Cell. 126: 1175-87. PMID 16990140 DOI: 10.1016/j.cell.2006.08.030  1
2006 Varoqueaux F, Aramuni G, Rawson RL, Mohrmann R, Missler M, Gottmann K, Zhang W, Südhof TC, Brose N. Neuroligins determine synapse maturation and function. Neuron. 51: 741-54. PMID 16982420 DOI: 10.1016/j.neuron.2006.09.003  1
2006 Deák F, Shin OH, Kavalali ET, Südhof TC. Structural determinants of synaptobrevin 2 function in synaptic vesicle fusion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6668-76. PMID 16793874 DOI: 10.1523/JNEUROSCI.5272-05.2006  1
2006 Sheckler LR, Henry L, Sugita S, Südhof TC, Rudenko G. Crystal structure of the second LNS/LG domain from neurexin 1alpha: Ca2+ binding and the effects of alternative splicing. The Journal of Biological Chemistry. 281: 22896-905. PMID 16772286 DOI: 10.1074/jbc.M603464200  0.76
2006 Deák F, Shin OH, Tang J, Hanson P, Ubach J, Jahn R, Rizo J, Kavalali ET, Südhof TC. Rabphilin regulates SNARE-dependent re-priming of synaptic vesicles for fusion. The Embo Journal. 25: 2856-66. PMID 16763567 DOI: 10.1038/sj.emboj.7601165  1
2006 Lu J, Machius M, Dulubova I, Dai H, Südhof TC, Tomchick DR, Rizo J. Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch. Plos Biology. 4: e192. PMID 16732694 DOI: 10.1371/journal.pbio.0040192  0.88
2006 Pang ZP, Sun J, Rizo J, Maximov A, Südhof TC. Genetic analysis of synaptotagmin 2 in spontaneous and Ca2+-triggered neurotransmitter release. The Embo Journal. 25: 2039-50. PMID 16642042 DOI: 10.1038/sj.emboj.7601103  0.96
2006 Araç D, Chen X, Khant HA, Ubach J, Ludtke SJ, Kikkawa M, Johnson AE, Chiu W, Südhof TC, Rizo J. Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nature Structural & Molecular Biology. 13: 209-17. PMID 16491093 DOI: 10.1038/nsmb1056  0.88
2006 Sun J, Bronk P, Liu X, Han W, Südhof TC. Synapsins regulate use-dependent synaptic plasticity in the calyx of Held by a Ca2+/calmodulin-dependent pathway. Proceedings of the National Academy of Sciences of the United States of America. 103: 2880-5. PMID 16481620 DOI: 10.1073/pnas.0511300103  1
2006 Schmitz F, Tabares L, Khimich D, Strenzke N, de la Villa-Polo P, Castellano-Muñoz M, Bulankina A, Moser T, Fernández-Chacón R, Südhof TC. CSPalpha-deficiency causes massive and rapid photoreceptor degeneration. Proceedings of the National Academy of Sciences of the United States of America. 103: 2926-31. PMID 16477021 DOI: 10.1073/pnas.0510060103  0.76
2006 Schlüter OM, Basu J, Südhof TC, Rosenmund C. Rab3 superprimes synaptic vesicles for release: implications for short-term synaptic plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1239-46. PMID 16436611 DOI: 10.1523/JNEUROSCI.3553-05.2006  1
2006 Nagy G, Kim JH, Pang ZP, Matti U, Rettig J, Südhof TC, Sørensen JB. Different effects on fast exocytosis induced by synaptotagmin 1 and 2 isoforms and abundance but not by phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 632-43. PMID 16407561 DOI: 10.1523/JNEUROSCI.2589-05.2006  0.96
2005 Rhee JS, Li LY, Shin OH, Rah JC, Rizo J, Südhof TC, Rosenmund C. Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1. Proceedings of the National Academy of Sciences of the United States of America. 102: 18664-9. PMID 16352718 DOI: 10.1073/pnas.0509153102  1
2005 Maximov A, Südhof TC. Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release. Neuron. 48: 547-54. PMID 16301172 DOI: 10.1016/j.neuron.2005.09.006  0.88
2005 Chandra S, Gallardo G, Fernández-Chacón R, Schlüter OM, Südhof TC. Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. Cell. 123: 383-96. PMID 16269331 DOI: 10.1016/j.cell.2005.09.028  1
2005 Kaeser PS, Südhof TC. RIM function in short- and long-term synaptic plasticity. Biochemical Society Transactions. 33: 1345-9. PMID 16246115 DOI: 10.1042/BST20051345  1
2005 Boucard AA, Chubykin AA, Comoletti D, Taylor P, Südhof TC. A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins. Neuron. 48: 229-36. PMID 16242404 DOI: 10.1016/j.neuron.2005.08.026  0.84
2005 Dai H, Tomchick DR, García J, Südhof TC, Machius M, Rizo J. Crystal structure of the RIM2 C2A-domain at 1.4 A resolution. Biochemistry. 44: 13533-42. PMID 16216076 DOI: 10.1021/bi0513608  0.88
2005 Lu J, Li H, Wang Y, Südhof TC, Rizo J. Solution structure of the RIM1alpha PDZ domain in complex with an ELKS1b C-terminal peptide. Journal of Molecular Biology. 352: 455-66. PMID 16095618 DOI: 10.1016/j.jmb.2005.07.047  1
2005 Dulubova I, Lou X, Lu J, Huryeva I, Alam A, Schneggenburger R, Südhof TC, Rizo J. A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? The Embo Journal. 24: 2839-50. PMID 16052212 DOI: 10.1038/sj.emboj.7600753  0.88
2005 Huang YY, Zakharenko SS, Schoch S, Kaeser PS, Janz R, Südhof TC, Siegelbaum SA, Kandel ER. Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation. Proceedings of the National Academy of Sciences of the United States of America. 102: 9365-70. PMID 15967982 DOI: 10.1073/pnas.0503777102  1
2005 Toonen RF, de Vries KJ, Zalm R, Südhof TC, Verhage M. Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation. Journal of Neurochemistry. 93: 1393-400. PMID 15935055 DOI: 10.1111/j.1471-4159.2005.03128.x  0.64
2005 Zhang W, Rohlmann A, Sargsyan V, Aramuni G, Hammer RE, Südhof TC, Missler M. Extracellular domains of alpha-neurexins participate in regulating synaptic transmission by selectively affecting N- and P/Q-type Ca2+ channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4330-42. PMID 15858059 DOI: 10.1523/JNEUROSCI.0497-05.2005  1
2005 Chubykin AA, Liu X, Comoletti D, Tsigelny I, Taylor P, Südhof TC. Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism. The Journal of Biological Chemistry. 280: 22365-74. PMID 15797875 DOI: 10.1074/jbc.M410723200  1
2005 Chen X, Tang J, Sudhof TC, Rizo J. Are neuronal SNARE proteins Ca2+ sensors? Journal of Molecular Biology. 347: 145-58. PMID 15733924 DOI: 10.1016/j.jmb.2005.01.024  0.88
2005 Fornai F, Schlüter OM, Lenzi P, Gesi M, Ruffoli R, Ferrucci M, Lazzeri G, Busceti CL, Pontarelli F, Battaglia G, Pellegrini A, Nicoletti F, Ruggieri S, Paparelli A, Südhof TC. Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein. Proceedings of the National Academy of Sciences of the United States of America. 102: 3413-8. PMID 15716361 DOI: 10.1073/pnas.0409713102  1
2005 Sara Y, Biederer T, Atasoy D, Chubykin A, Mozhayeva MG, Südhof TC, Kavalali ET. Selective capability of SynCAM and neuroligin for functional synapse assembly. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 260-70. PMID 15634790 DOI: 10.1523/JNEUROSCI.3165-04.2005  1
2005 Han W, Rhee JS, Maximov A, Lin W, Hammer RE, Rosenmund C, Südhof TC. C-terminal ECFP fusion impairs synaptotagmin 1 function: crowding out synaptotagmin 1. The Journal of Biological Chemistry. 280: 5089-100. PMID 15561725 DOI: 10.1074/jbc.M408757200  1
2005 Shin OH, Han W, Wang Y, Südhof TC. Evolutionarily conserved multiple C2 domain proteins with two transmembrane regions (MCTPs) and unusual Ca2+ binding properties. The Journal of Biological Chemistry. 280: 1641-51. PMID 15528213 DOI: 10.1074/jbc.M407305200  1
2004 Khvotchev MV, Südhof TC. Stimulus-dependent dynamic homo- and heteromultimerization of synaptobrevin/VAMP and synaptophysin. Biochemistry. 43: 15037-43. PMID 15554711 DOI: 10.1021/bi048290+  0.64
2004 Deák F, Schoch S, Liu X, Südhof TC, Kavalali ET. Synaptobrevin is essential for fast synaptic-vesicle endocytosis. Nature Cell Biology. 6: 1102-8. PMID 15475946 DOI: 10.1038/ncb1185  1
2004 Chandra S, Fornai F, Kwon HB, Yazdani U, Atasoy D, Liu X, Hammer RE, Battaglia G, German DC, Castillo PE, Südhof TC. Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions. Proceedings of the National Academy of Sciences of the United States of America. 101: 14966-71. PMID 15465911 DOI: 10.1073/pnas.0406283101  1
2004 Khvotchev M, Südhof TC. Proteolytic processing of amyloid-beta precursor protein by secretases does not require cell surface transport. The Journal of Biological Chemistry. 279: 47101-8. PMID 15316009 DOI: 10.1074/jbc.M408474200  0.8
2004 Dai H, Shin OH, Machius M, Tomchick DR, Südhof TC, Rizo J. Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4. Nature Structural & Molecular Biology. 11: 844-9. PMID 15311271 DOI: 10.1038/nsmb817  1
2004 Dulubova I, Ho A, Huryeva I, Südhof TC, Rizo J. Three-dimensional structure of an independently folded extracellular domain of human amyloid-beta precursor protein. Biochemistry. 43: 9583-8. PMID 15274612 DOI: 10.1021/bi049041o  1
2004 Schlüter OM, Schmitz F, Jahn R, Rosenmund C, Südhof TC. A complete genetic analysis of neuronal Rab3 function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6629-37. PMID 15269275 DOI: 10.1523/JNEUROSCI.1610-04.2004  1
2004 Calakos N, Schoch S, Südhof TC, Malenka RC. Multiple roles for the active zone protein RIM1alpha in late stages of neurotransmitter release. Neuron. 42: 889-96. PMID 15207234 DOI: 10.1016/j.neuron.2004.05.014  1
2004 Fernández-Chacón R, Wölfel M, Nishimune H, Tabares L, Schmitz F, Castellano-Muñoz M, Rosenmund C, Montesinos ML, Sanes JR, Schneggenburger R, Südhof TC. The synaptic vesicle protein CSP alpha prevents presynaptic degeneration. Neuron. 42: 237-51. PMID 15091340  1
2004 Powell CM, Schoch S, Monteggia L, Barrot M, Matos MF, Feldmann N, Südhof TC, Nestler EJ. The presynaptic active zone protein RIM1alpha is critical for normal learning and memory. Neuron. 42: 143-53. PMID 15066271  0.92
2004 Cao X, Südhof TC. Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation. The Journal of Biological Chemistry. 279: 24601-11. PMID 15044485 DOI: 10.1074/jbc.M402248200  0.92
2004 Kattenstroth G, Tantalaki E, Südhof TC, Gottmann K, Missler M. Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins. Proceedings of the National Academy of Sciences of the United States of America. 101: 2607-12. PMID 14983056  1
2004 Shin OH, Maximov A, Lim BK, Rizo J, Südhof TC. Unexpected Ca2+-binding properties of synaptotagmin 9. Proceedings of the National Academy of Sciences of the United States of America. 101: 2554-9. PMID 14983047  1
2004 Ho A, Südhof TC. Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage. Proceedings of the National Academy of Sciences of the United States of America. 101: 2548-53. PMID 14983046  1
2004 Hoffman RC, Jennings LL, Tsigelny I, Comoletti D, Flynn RE, Sudhof TC, Taylor P. Structural characterization of recombinant soluble rat neuroligin 1: mapping of secondary structure and glycosylation by mass spectrometry. Biochemistry. 43: 1496-506. PMID 14769026 DOI: 10.1021/bi035278t  0.56
2004 Garcia J, Gerber SH, Sugita S, Südhof TC, Rizo J. A conformational switch in the Piccolo C2A domain regulated by alternative splicing. Nature Structural & Molecular Biology. 11: 45-53. PMID 14718922 DOI: 10.1038/nsmb707  0.88
2004 Han W, Rhee JS, Maximov A, Lao Y, Mashimo T, Rosenmund C, Südhof TC. N-glycosylation is essential for vesicular targeting of synaptotagmin 1. Neuron. 41: 85-99. PMID 14715137  1
2004 Li Q, Südhof TC. Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1. The Journal of Biological Chemistry. 279: 10542-50. PMID 14699153 DOI: 10.1074/jbc.M310001200  0.84
2003 Khvotchev MV, Ren M, Takamori S, Jahn R, Südhof TC. Divergent functions of neuronal Rab11b in Ca2+-regulated versus constitutive exocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10531-9. PMID 14627637  0.96
2003 Virmani T, Han W, Liu X, Südhof TC, Kavalali ET. Synaptotagmin 7 splice variants differentially regulate synaptic vesicle recycling. The Embo Journal. 22: 5347-57. PMID 14532108 DOI: 10.1093/emboj/cdg514  1
2003 Lonart G, Schoch S, Kaeser PS, Larkin CJ, Südhof TC, Linden DJ. Phosphorylation of RIM1alpha by PKA triggers presynaptic long-term potentiation at cerebellar parallel fiber synapses. Cell. 115: 49-60. PMID 14532002  1
2003 Matos MF, Mukherjee K, Chen X, Rizo J, Südhof TC. Evidence for SNARE zippering during Ca2+-triggered exocytosis in PC12 cells. Neuropharmacology. 45: 777-86. PMID 14529716  0.88
2003 Comoletti D, Flynn R, Jennings LL, Chubykin A, Matsumura T, Hasegawa H, Südhof TC, Taylor P. Characterization of the interaction of a recombinant soluble neuroligin-1 with neurexin-1beta. The Journal of Biological Chemistry. 278: 50497-505. PMID 14522992 DOI: 10.1074/jbc.M306803200  0.72
2003 Sørensen JB, Fernández-Chacón R, Südhof TC, Neher E. Examining synaptotagmin 1 function in dense core vesicle exocytosis under direct control of Ca2+. The Journal of General Physiology. 122: 265-76. PMID 12939392 DOI: 10.1085/jgp.200308855  0.72
2003 Missler M, Zhang W, Rohlmann A, Kattenstroth G, Hammer RE, Gottmann K, Südhof TC. Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis. Nature. 423: 939-48. PMID 12827191 DOI: 10.1038/nature01755  1
2003 Schlüter OM, Fornai F, Alessandrí MG, Takamori S, Geppert M, Jahn R, Südhof TC. Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice. Neuroscience. 118: 985-1002. PMID 12732244  0.92
2003 Wang Y, Südhof TC. Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins. Genomics. 81: 126-37. PMID 12620390  1
2003 Jahn R, Lang T, Südhof TC. Membrane fusion. Cell. 112: 519-33. PMID 12600315  0.96
2003 Chandra S, Chen X, Rizo J, Jahn R, Südhof TC. A broken alpha -helix in folded alpha -Synuclein. The Journal of Biological Chemistry. 278: 15313-8. PMID 12586824 DOI: 10.1074/jbc.M213128200  0.96
2003 Ho A, Morishita W, Hammer RE, Malenka RC, Sudhof TC. A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission. Proceedings of the National Academy of Sciences of the United States of America. 100: 1409-14. PMID 12547917 DOI: 10.1073/pnas.252774899  1
2003 Shin OH, Rhee JS, Tang J, Sugita S, Rosenmund C, Südhof TC. Sr2+ binding to the Ca2+ binding site of the synaptotagmin 1 C2B domain triggers fast exocytosis without stimulating SNARE interactions. Neuron. 37: 99-108. PMID 12526776  1
2003 Dulubova I, Yamaguchi T, Arac D, Li H, Huryeva I, Min SW, Rizo J, Sudhof TC. Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins. Proceedings of the National Academy of Sciences of the United States of America. 100: 32-7. PMID 12506202 DOI: 10.1073/pnas.232701299  0.88
2002 Wang Y, Liu X, Biederer T, Südhof TC. A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones. Proceedings of the National Academy of Sciences of the United States of America. 99: 14464-9. PMID 12391317 DOI: 10.1073/pnas.182532999  1
2002 Fernández-Chacón R, Shin OH, Königstorfer A, Matos MF, Meyer AC, Garcia J, Gerber SH, Rizo J, Südhof TC, Rosenmund C. Structure/function analysis of Ca2+ binding to the C2A domain of synaptotagmin 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8438-46. PMID 12351718  1
2002 Barylko B, Wlodarski P, Binns DD, Gerber SH, Earnest S, Sudhof TC, Grichine N, Albanesi JP. Analysis of the catalytic domain of phosphatidylinositol 4-kinase type II. The Journal of Biological Chemistry. 277: 44366-75. PMID 12215430 DOI: 10.1074/jbc.M203241200  0.72
2002 Biederer T, Sara Y, Mozhayeva M, Atasoy D, Liu X, Kavalali ET, Südhof TC. SynCAM, a synaptic adhesion molecule that drives synapse assembly. Science (New York, N.Y.). 297: 1525-31. PMID 12202822 DOI: 10.1126/science.1072356  1
2002 Biederer T, Cao X, Südhof TC, Liu X. Regulation of APP-dependent transcription complexes by Mint/X11s: differential functions of Mint isoforms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7340-51. PMID 12196555  1
2002 Riedel D, Antonin W, Fernandez-Chacon R, Alvarez de Toledo G, Jo T, Geppert M, Valentijn JA, Valentijn K, Jamieson JD, Südhof TC, Jahn R. Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules. Molecular and Cellular Biology. 22: 6487-97. PMID 12192047  0.96
2002 Schlüter OM, Khvotchev M, Jahn R, Südhof TC. Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion. The Journal of Biological Chemistry. 277: 40919-29. PMID 12167638 DOI: 10.1074/jbc.M203704200  1
2002 Rizo J, Südhof TC. Snares and Munc18 in synaptic vesicle fusion. Nature Reviews. Neuroscience. 3: 641-53. PMID 12154365 DOI: 10.1038/nrn898  0.88
2002 Dulubova I, Yamaguchi T, Gao Y, Min SW, Huryeva I, Südhof TC, Rizo J. How Tlg2p/syntaxin 16 'snares' Vps45. The Embo Journal. 21: 3620-31. PMID 12110575 DOI: 10.1093/emboj/cdf381  0.88
2002 Shin OH, Rizo J, Südhof TC. Synaptotagmin function in dense core vesicle exocytosis studied in cracked PC12 cells. Nature Neuroscience. 5: 649-56. PMID 12055633 DOI: 10.1038/nn869  1
2002 Sugita S, Ho A, Südhof TC. NECABs: a family of neuronal Ca(2+)-binding proteins with an unusual domain structure and a restricted expression pattern. Neuroscience. 112: 51-63. PMID 12044471 DOI: 10.1016/S0306-4522(02)00063-5  1
2002 Tabuchi K, Biederer T, Butz S, Sudhof TC. CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with caskin 1, a novel CASK-binding protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4264-73. PMID 12040031  1
2002 Tabuchi K, Südhof TC. Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing. Genomics. 79: 849-59. PMID 12036300 DOI: 10.1006/geno.2002.6780  0.92
2002 Lu J, Garcia J, Dulubova I, Südhof TC, Rizo J. Solution structure of the Vam7p PX domain. Biochemistry. 41: 5956-62. PMID 11993989  0.88
2002 Yamaguchi T, Dulubova I, Min SW, Chen X, Rizo J, Südhof TC. Sly1 binds to Golgi and ER syntaxins via a conserved N-terminal peptide motif. Developmental Cell. 2: 295-305. PMID 11879635  0.88
2002 Chen X, Tomchick DR, Kovrigin E, Araç D, Machius M, Südhof TC, Rizo J. Three-dimensional structure of the complexin/SNARE complex. Neuron. 33: 397-409. PMID 11832227  0.88
2002 Sugita S, Shin OH, Han W, Lao Y, Südhof TC. Synaptotagmins form a hierarchy of exocytotic Ca(2+) sensors with distinct Ca(2+) affinities. The Embo Journal. 21: 270-80. PMID 11823420 DOI: 10.1093/emboj/21.3.270  1
2002 Gerber SH, Rizo J, Südhof TC. Role of electrostatic and hydrophobic interactions in Ca(2+)-dependent phospholipid binding by the C(2)A-domain from synaptotagmin I. Diabetes. 51: S12-8. PMID 11815451  0.88
2002 Gerber SH, Südhof TC. Molecular determinants of regulated exocytosis. Diabetes. 51: S3-11. PMID 11815450  0.72
2002 Castillo PE, Schoch S, Schmitz F, Südhof TC, Malenka RC. RIM1alpha is required for presynaptic long-term potentiation. Nature. 415: 327-30. PMID 11797010 DOI: 10.1038/415327a  1
2002 Schoch S, Castillo PE, Jo T, Mukherjee K, Geppert M, Wang Y, Schmitz F, Malenka RC, Südhof TC. RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone. Nature. 415: 321-6. PMID 11797009 DOI: 10.1038/415321a  1
2002 Rhee JS, Betz A, Pyott S, Reim K, Varoqueaux F, Augustin I, Hesse D, Südhof TC, Takahashi M, Rosenmund C, Brose N. Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs. Cell. 108: 121-33. PMID 11792326  1
2002 Tobaben S, Südhof TC, Stahl B. Genetic analysis of alpha-latrotoxin receptors reveals functional interdependence of CIRL/latrophilin 1 and neurexin 1 alpha. The Journal of Biological Chemistry. 277: 6359-65. PMID 11741895 DOI: 10.1074/jbc.M111231200  0.92
2002 Südhof TC. Synaptotagmins: why so many? The Journal of Biological Chemistry. 277: 7629-32. PMID 11739399 DOI: 10.1074/jbc.R100052200  0.92
2001 Fernandez I, Araç D, Ubach J, Gerber SH, Shin O, Gao Y, Anderson RG, Südhof TC, Rizo J. Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine. Neuron. 32: 1057-69. PMID 11754837  0.92
2001 Schoch S, Deák F, Königstorfer A, Mozhayeva M, Sara Y, Südhof TC, Kavalali ET. SNARE function analyzed in synaptobrevin/VAMP knockout mice. Science (New York, N.Y.). 294: 1117-22. PMID 11691998 DOI: 10.1126/science.1064335  1
2001 Lonart G, Südhof TC. Characterization of rabphilin phosphorylation using phospho-specific antibodies. Neuropharmacology. 41: 643-9. PMID 11640918  0.92
2001 Biederer T, Sudhof TC. CASK and protein 4.1 support F-actin nucleation on neurexins. The Journal of Biological Chemistry. 276: 47869-76. PMID 11604393 DOI: 10.1074/jbc.M105287200  1
2001 Tobaben S, Thakur P, Fernández-Chacón R, Südhof TC, Rettig J, Stahl B. A trimeric protein complex functions as a synaptic chaperone machine. Neuron. 31: 987-99. PMID 11580898  0.92
2001 Honarpour N, Tabuchi K, Stark JM, Hammer RE, Südhof TC, Parada LF, Wang X, Richardson JA, Herz J. Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of Apaf-1. Neuroscience. 106: 263-74. PMID 11566499  0.96
2001 Voets T, Moser T, Lund PE, Chow RH, Geppert M, Südhof TC, Neher E. Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I. Proceedings of the National Academy of Sciences of the United States of America. 98: 11680-5. PMID 11562488 DOI: 10.1073/pnas.201398798  1
2001 Voets T, Toonen RF, Brian EC, de Wit H, Moser T, Rettig J, Südhof TC, Neher E, Verhage M. Munc18-1 promotes large dense-core vesicle docking. Neuron. 31: 581-91. PMID 11545717 DOI: 10.1016/S0896-6273(01)00391-9  1
2001 Südhof TC. alpha-Latrotoxin and its receptors: neurexins and CIRL/latrophilins. Annual Review of Neuroscience. 24: 933-62. PMID 11520923 DOI: 10.1146/annurev.neuro.24.1.933  0.92
2001 Sugita S, Saito F, Tang J, Satz J, Campbell K, Südhof TC. A stoichiometric complex of neurexins and dystroglycan in brain. The Journal of Cell Biology. 154: 435-45. PMID 11470830 DOI: 10.1083/jcb.200105003  1
2001 Gerber SH, Rizo J, Südhof TC. The top loops of the C(2) domains from synaptotagmin and phospholipase A(2) control functional specificity. The Journal of Biological Chemistry. 276: 32288-92. PMID 11447211 DOI: 10.1074/jbc.C100108200  0.92
2001 Cao X, Südhof TC. A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science (New York, N.Y.). 293: 115-20. PMID 11441186 DOI: 10.1126/science.1058783  0.92
2001 Sugita S, Han W, Butz S, Liu X, Fernández-Chacón R, Lao Y, Südhof TC. Synaptotagmin VII as a plasma membrane Ca(2+) sensor in exocytosis. Neuron. 30: 459-73. PMID 11395007  0.92
2001 Ubach J, Lao Y, Fernandez I, Arac D, Südhof TC, Rizo J. The C2B domain of synaptotagmin I is a Ca2+-binding module. Biochemistry. 40: 5854-60. PMID 11352720  0.92
2001 Wang Y, Dulubova I, Rizo J, Südhof TC. Functional analysis of conserved structural elements in yeast syntaxin Vam3p. The Journal of Biological Chemistry. 276: 28598-605. PMID 11349128 DOI: 10.1074/jbc.M101644200  0.92
2001 Gerber SH, Garcia J, Rizo J, Südhof TC. An unusual C(2)-domain in the active-zone protein piccolo: implications for Ca(2+) regulation of neurotransmitter release. The Embo Journal. 20: 1605-19. PMID 11285225 DOI: 10.1093/emboj/20.7.1605  0.92
2001 Barylko B, Gerber SH, Binns DD, Grichine N, Khvotchev M, Südhof TC, Albanesi JP. A novel family of phosphatidylinositol 4-kinases conserved from yeast to humans. The Journal of Biological Chemistry. 276: 7705-8. PMID 11244087 DOI: 10.1074/jbc.C000861200  0.92
2001 Fernández-Chacón R, Königstorfer A, Gerber SH, García J, Matos MF, Stevens CF, Brose N, Rizo J, Rosenmund C, Südhof TC. Synaptotagmin I functions as a calcium regulator of release probability. Nature. 410: 41-9. PMID 11242035 DOI: 10.1038/35065004  1
2001 Dulubova I, Yamaguchi T, Wang Y, Südhof TC, Rizo J. Vam3p structure reveals conserved and divergent properties of syntaxins. Nature Structural Biology. 8: 258-64. PMID 11224573 DOI: 10.1038/85012  0.92
2001 von Poser C, Südhof TC. Synaptotagmin 13: structure and expression of a novel synaptotagmin. European Journal of Cell Biology. 80: 41-7. PMID 11211934  0.92
2001 Reim K, Mansour M, Varoqueaux F, McMahon HT, Südhof TC, Brose N, Rosenmund C. Complexins regulate a late step in Ca2+-dependent neurotransmitter release. Cell. 104: 71-81. PMID 11163241 DOI: 10.1016/S0092-8674(01)00192-1  1
2001 Augustin I, Korte S, Rickmann M, Kretzschmar HA, Südhof TC, Herms JW, Brose N. The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 10-7. PMID 11150314  1
2000 Schmitz F, Königstorfer A, Südhof TC. RIBEYE, a component of synaptic ribbons: a protein's journey through evolution provides insight into synaptic ribbon function. Neuron. 28: 857-72. PMID 11163272  0.92
2000 Südhof TC. The synaptic vesicle cycle revisited. Neuron. 28: 317-20. PMID 11144340  0.92
2000 Khvotchev M, Lonart G, Südhof TC. Role of calcium in neurotransmitter release evoked by alpha-latrotoxin or hypertonic sucrose. Neuroscience. 101: 793-802. PMID 11113328  0.92
2000 Fernández-Chacón R, Südhof TC. Novel SCAMPs lacking NPF repeats: ubiquitous and synaptic vesicle-specific forms implicate SCAMPs in multiple membrane-trafficking functions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7941-50. PMID 11050114  1
2000 Biederer T, Südhof TC. Mints as adaptors. Direct binding to neurexins and recruitment of munc18. The Journal of Biological Chemistry. 275: 39803-6. PMID 11036064 DOI: 10.1074/jbc.C000656200  1
2000 Lonart G, Südhof TC. Assembly of SNARE core complexes prior to neurotransmitter release sets the readily releasable pool of synaptic vesicles. The Journal of Biological Chemistry. 275: 27703-7. PMID 10970903  0.92
2000 Tobaben S, Südhof TC, Stahl B. The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family. The Journal of Biological Chemistry. 275: 36204-10. PMID 10958799 DOI: 10.1074/jbc.M006448200  0.92
2000 Matos MF, Rizo J, Südhof TC. The relation of protein binding to function: what is the significance of munc18 and synaptotagmin binding to syntaxin 1, and where are the corresponding binding sites? European Journal of Cell Biology. 79: 377-82. PMID 10928452  0.92
2000 Zhang W, Li JL, Hosaka M, Janz R, Shelton JM, Albright GM, Richardson JA, Südhof TC, Victor RG. Cyclosporine A-induced hypertension involves synapsin in renal sensory nerve endings. Proceedings of the National Academy of Sciences of the United States of America. 97: 9765-70. PMID 10920204 DOI: 10.1073/pnas.170160397  0.92
2000 von Poser C, Zhang JZ, Mineo C, Ding W, Ying Y, Sudhof TC, Anderson RG. Synaptotagmin regulation of coated pit assembly. The Journal of Biological Chemistry. 275: 30916-24. PMID 10906143 DOI: 10.1074/jbc.M005559200  0.76
2000 Khvotchev M, Südhof TC. alpha-latrotoxin triggers transmitter release via direct insertion into the presynaptic plasma membrane. The Embo Journal. 19: 3250-62. PMID 10880438 DOI: 10.1093/emboj/19.13.3250  0.92
2000 Fernández-Chacón R, Achiriloaie M, Janz R, Albanesi JP, Südhof TC. SCAMP1 function in endocytosis. The Journal of Biological Chemistry. 275: 12752-6. PMID 10777571  0.92
2000 Pabst S, Hazzard JW, Antonin W, Südhof TC, Jahn R, Rizo J, Fasshauer D. Selective interaction of complexin with the neuronal SNARE complex. Determination of the binding regions. The Journal of Biological Chemistry. 275: 19808-18. PMID 10777504 DOI: 10.1074/jbc.M002571200  0.92
2000 Wang Y, Sugita S, Sudhof TC. The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins. The Journal of Biological Chemistry. 275: 20033-44. PMID 10748113 DOI: 10.1074/jbc.M909008199  1
2000 Tsigelny I, Shindyalov IN, Bourne PE, Südhof TC, Taylor P. Common EF-hand motifs in cholinesterases and neuroligins suggest a role for Ca2+ binding in cell surface associations. Protein Science : a Publication of the Protein Society. 9: 180-5. PMID 10739260 DOI: 10.1110/ps.9.1.180  0.92
2000 Sugita S, Südhof TC. Specificity of Ca2+-dependent protein interactions mediated by the C2A domains of synaptotagmins. Biochemistry. 39: 2940-9. PMID 10715114  0.92
2000 Verhage M, Maia AS, Plomp JJ, Brussaard AB, Heeroma JH, Vermeer H, Toonen RF, Hammer RE, van den Berg TK, Missler M, Geuze HJ, Südhof TC. Synaptic assembly of the brain in the absence of neurotransmitter secretion. Science (New York, N.Y.). 287: 864-9. PMID 10657302 DOI: 10.1126/science.287.5454.864  1
1999 Jahn R, Südhof TC. Membrane fusion and exocytosis. Annual Review of Biochemistry. 68: 863-911. PMID 10872468 DOI: 10.1146/annurev.biochem.68.1.863  1
1999 Janz R, Südhof TC. SV2C is a synaptic vesicle protein with an unusually restricted localization: anatomy of a synaptic vesicle protein family. Neuroscience. 94: 1279-90. PMID 10625067  0.92
1999 Janz R, Goda Y, Geppert M, Missler M, Südhof TC. SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release. Neuron. 24: 1003-16. PMID 10624962  1
1999 Janz R, Südhof TC, Hammer RE, Unni V, Siegelbaum SA, Bolshakov VY. Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I. Neuron. 24: 687-700. PMID 10595519  1
1999 Hosaka M, Hammer RE, Südhof TC. A phospho-switch controls the dynamic association of synapsins with synaptic vesicles. Neuron. 24: 377-87. PMID 10571231  0.92
1999 Ubach J, García J, Nittler MP, Südhof TC, Rizo J. Structure of the Janus-faced C2B domain of rabphilin. Nature Cell Biology. 1: 106-12. PMID 10559882 DOI: 10.1038/10076  1
1999 Fernández-Chacón R, Alvarez de Toledo G, Hammer RE, Südhof TC. Analysis of SCAMP1 function in secretory vesicle exocytosis by means of gene targeting in mice. The Journal of Biological Chemistry. 274: 32551-4. PMID 10551807  0.92
1999 Rudenko G, Nguyen T, Chelliah Y, Südhof TC, Deisenhofer J. The structure of the ligand-binding domain of neurexin Ibeta: regulation of LNS domain function by alternative splicing. Cell. 99: 93-101. PMID 10520997 DOI: 10.1016/S0092-8674(00)80065-3  1
1999 Hazzard J, Südhof TC, Rizo J. NMR analysis of the structure of synaptobrevin and of its interaction with syntaxin. Journal of Biomolecular Nmr. 14: 203-7. PMID 10481273  0.92
1999 Maximov A, Südhof TC, Bezprozvanny I. Association of neuronal calcium channels with modular adaptor proteins. The Journal of Biological Chemistry. 274: 24453-6. PMID 10455105 DOI: 10.1074/jbc.274.35.24453  1
1999 Dulubova I, Sugita S, Hill S, Hosaka M, Fernandez I, Südhof TC, Rizo J. A conformational switch in syntaxin during exocytosis: role of munc18. The Embo Journal. 18: 4372-82. PMID 10449403 DOI: 10.1093/emboj/18.16.4372  0.92
1999 Augustin I, Rosenmund C, Südhof TC, Brose N. Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles. Nature. 400: 457-61. PMID 10440375 DOI: 10.1038/22768  1
1999 Stahl B, Tobaben S, Südhof TC. Two distinct domains in hsc70 are essential for the interaction with the synaptic vesicle cysteine string protein. European Journal of Cell Biology. 78: 375-81. PMID 10430018 DOI: 10.1016/S0171-9335(99)80079-X  0.92
1999 Schlüter OM, Schnell E, Verhage M, Tzonopoulos T, Nicoll RA, Janz R, Malenka RC, Geppert M, Südhof TC. Rabphilin knock-out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5834-46. PMID 10407024  1
1999 Butz S, Fernandez-Chacon R, Schmitz F, Jahn R, Südhof TC. The subcellular localizations of atypical synaptotagmins III and VI. Synaptotagmin III is enriched in synapses and synaptic plasma membranes but not in synaptic vesicles. The Journal of Biological Chemistry. 274: 18290-6. PMID 10373432 DOI: 10.1074/jbc.274.26.18290  1
1999 Fernández-Chacón R, Südhof TC. Genetics of synaptic vesicle function: toward the complete functional anatomy of an organelle. Annual Review of Physiology. 61: 753-76. PMID 10099709 DOI: 10.1146/annurev.physiol.61.1.753  0.92
1999 Song JY, Ichtchenko K, Südhof TC, Brose N. Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses. Proceedings of the National Academy of Sciences of the United States of America. 96: 1100-5. PMID 9927700 DOI: 10.1073/pnas.96.3.1100  1
1998 Missler M, Hammer RE, Südhof TC. Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit. The Journal of Biological Chemistry. 273: 34716-23. PMID 9856994 DOI: 10.1074/jbc.273.52.34716  1
1998 Missler M, Fernandez-Chacon R, Südhof TC. The making of neurexins. Journal of Neurochemistry. 71: 1339-47. PMID 9751164  1
1998 Betz A, Ashery U, Rickmann M, Augustin I, Neher E, Südhof TC, Rettig J, Brose N. Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release. Neuron. 21: 123-36. PMID 9697857 DOI: 10.1016/S0896-6273(00)80520-6  1
1998 Missler M, Südhof TC. Neurexophilins form a conserved family of neuropeptide-like glycoproteins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 3630-8. PMID 9570794  1
1998 Missler M, Südhof TC. Neurexins: three genes and 1001 products. Trends in Genetics : Tig. 14: 20-6. PMID 9448462 DOI: 10.1016/S0168-9525(97)01324-3  1
1998 Geppert M, Khvotchev M, Krasnoperov V, Goda Y, Missler M, Hammer RE, Ichtchenko K, Petrenko AG, Südhof TC. Neurexin I alpha is a major alpha-latrotoxin receptor that cooperates in alpha-latrotoxin action. The Journal of Biological Chemistry. 273: 1705-10. PMID 9430716 DOI: 10.1074/jbc.273.3.1705  1
1997 Telemenakis I, Benseler F, Stenius K, Südhof TC, Brose N. Rat homologues of yeast sec7p. European Journal of Cell Biology. 74: 143-9. PMID 9352219  1
1997 Verhage M, de Vries KJ, Røshol H, Burbach JP, Gispen WH, Südhof TC. DOC2 proteins in rat brain: complementary distribution and proposed function as vesicular adapter proteins in early stages of secretion. Neuron. 18: 453-61. PMID 9115738 DOI: 10.1016/S0896-6273(00)81245-3  1
1996 Chapman ER, Blasi J, An S, Brose N, Johnston PA, Südhof TC, Jahn R. Fatty acylation of synaptotagmin in PC12 cells and synaptosomes. Biochemical and Biophysical Research Communications. 225: 326-32. PMID 8769138 DOI: 10.1006/bbrc.1996.1174  1
1996 Petrenko AG, Ullrich B, Missler M, Krasnoperov V, Rosahl TW, Südhof TC. Structure and evolution of neurexophilin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 4360-9. PMID 8699246  1
1995 Li C, Ullrich B, Zhang JZ, Anderson RG, Brose N, Südhof TC. Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. Nature. 375: 594-9. PMID 7791877 DOI: 10.1038/375594a0  1
1995 Rosahl TW, Spillane D, Missler M, Herz J, Selig DK, Wolff JR, Hammer RE, Malenka RC, Südhof TC. Essential functions of synapsins I and II in synaptic vesicle regulation. Nature. 375: 488-93. PMID 7777057 DOI: 10.1038/375488a0  1
1995 Ichtchenko K, Hata Y, Nguyen T, Ullrich B, Missler M, Moomaw C, Südhof TC. Neuroligin 1: a splice site-specific ligand for beta-neurexins. Cell. 81: 435-43. PMID 7736595 DOI: 10.1016/0092-8674(95)90396-8  1
1995 Ullrich B, Ushkaryov YA, Südhof TC. Cartography of neurexins: more than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons. Neuron. 14: 497-507. PMID 7695896 DOI: 10.1016/0896-6273(95)90306-2  1
1995 Brose N, Hofmann K, Hata Y, Südhof TC. Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins. The Journal of Biological Chemistry. 270: 25273-80. PMID 7559667 DOI: 10.1074/jbc.270.42.25273  1
1995 McMahon HT, Missler M, Li C, Südhof TC. Complexins: cytosolic proteins that regulate SNAP receptor function. Cell. 83: 111-9. PMID 7553862 DOI: 10.1016/0092-8674(95)90239-2  1
1994 Sontag JM, Fykse EM, Ushkaryov Y, Liu JP, Robinson PJ, Südhof TC. Differential expression and regulation of multiple dynamins. The Journal of Biological Chemistry. 269: 4547-54. PMID 8308025  1
1994 Ushkaryov YA, Hata Y, Ichtchenko K, Moomaw C, Afendis S, Slaughter CA, Südhof TC. Conserved domain structure of beta-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins. The Journal of Biological Chemistry. 269: 11987-92. PMID 8163501  1
1993 Armstrong SA, Seabra MC, Südhof TC, Goldstein JL, Brown MS. cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase. The Journal of Biological Chemistry. 268: 12221-9. PMID 8505342  1
1993 Petrenko AG, Lazaryeva VD, Geppert M, Tarasyuk TA, Moomaw C, Khokhlatchev AV, Ushkaryov YA, Slaughter C, Nasimov IV, Südhof TC. Polypeptide composition of the alpha-latrotoxin receptor. High affinity binding protein consists of a family of related high molecular weight polypeptides complexed to a low molecular weight protein. The Journal of Biological Chemistry. 268: 1860-7. PMID 8420960  1
1993 Ushkaryov YA, Südhof TC. Neurexin III alpha: extensive alternative splicing generates membrane-bound and soluble forms. Proceedings of the National Academy of Sciences of the United States of America. 90: 6410-4. PMID 8341647  1
1993 McMahon HT, Ushkaryov YA, Edelmann L, Link E, Binz T, Niemann H, Jahn R, Südhof TC. Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein. Nature. 364: 346-9. PMID 8332193 DOI: 10.1038/364346a0  1
1993 Südhof TC, Petrenko AG, Whittaker VP, Jahn R. Molecular approaches to synaptic vesicle exocytosis. Progress in Brain Research. 98: 235-40. PMID 8248512  0.92
1992 Ushkaryov YA, Petrenko AG, Geppert M, Südhof TC. Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin. Science (New York, N.Y.). 257: 50-6. PMID 1621094  1
1992 Brose N, Petrenko AG, Südhof TC, Jahn R. Synaptotagmin: a calcium sensor on the synaptic vesicle surface. Science (New York, N.Y.). 256: 1021-5. PMID 1589771  1
1992 Seabra MC, Brown MS, Slaughter CA, Südhof TC, Goldstein JL. Purification of component A of Rab geranylgeranyl transferase: possible identity with the choroideremia gene product. Cell. 70: 1049-57. PMID 1525821  0.84
1992 Geppert M, Ushkaryov YA, Hata Y, Davletov B, Petrenko AG, Südhof TC. Neurexins. Cold Spring Harbor Symposia On Quantitative Biology. 57: 483-90. PMID 1339684  1
1992 Seabra MC, Goldstein JL, Südhof TC, Brown MS. Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys. The Journal of Biological Chemistry. 267: 14497-503. PMID 1321151  0.84
1991 Perin MS, Brose N, Jahn R, Südhof TC. Domain structure of synaptotagmin (p65) The Journal of Biological Chemistry. 266: 623-9. PMID 1985919  1
1991 Petrenko AG, Perin MS, Davletov BA, Ushkaryov YA, Geppert M, Südhof TC. Binding of synaptotagmin to the alpha-latrotoxin receptor implicates both in synaptic vesicle exocytosis. Nature. 353: 65-8. PMID 1881448 DOI: 10.1038/353065a0  1
1991 Südhof TC, Newton CL, Archer BT, Ushkaryov YA, Mignery GA. Structure of a novel InsP3 receptor. The Embo Journal. 10: 3199-206. PMID 1655411  1
1988 Dawson PA, Hofmann SL, van der Westhuyzen DR, Südhof TC, Brown MS, Goldstein JL. Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1. The Journal of Biological Chemistry. 263: 3372-9. PMID 3277969  0.84
1987 Südhof TC, Van der Westhuyzen DR, Goldstein JL, Brown MS, Russell DW. Three direct repeats and a TATA-like sequence are required for regulated expression of the human low density lipoprotein receptor gene. The Journal of Biological Chemistry. 262: 10773-9. PMID 3611089  0.84
1987 Davis CG, Goldstein JL, Südhof TC, Anderson RG, Russell DW, Brown MS. Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region. Nature. 326: 760-5. PMID 3494949 DOI: 10.1038/326760a0  1
1987 van Driel IR, Goldstein JL, Südhof TC, Brown MS. First cysteine-rich repeat in ligand-binding domain of low density lipoprotein receptor binds Ca2+ and monoclonal antibodies, but not lipoproteins. The Journal of Biological Chemistry. 262: 17443-9. PMID 3320043  0.84
1987 Südhof TC, Russell DW, Brown MS, Goldstein JL. 42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter. Cell. 48: 1061-9. PMID 3030558  0.84
1986 Russell DW, Lehrman MA, Südhof TC, Yamamoto T, Davis CG, Hobbs HH, Brown MS, Goldstein JL. The LDL receptor in familial hypercholesterolemia: use of human mutations to dissect a membrane protein. Cold Spring Harbor Symposia On Quantitative Biology. 51: 811-9. PMID 3472763  1
1986 Ma PT, Gil G, Südhof TC, Bilheimer DW, Goldstein JL, Brown MS. Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits. Proceedings of the National Academy of Sciences of the United States of America. 83: 8370-4. PMID 3464957  0.84
1985 Südhof TC, Russell DW, Goldstein JL, Brown MS, Sanchez-Pescador R, Bell GI. Cassette of eight exons shared by genes for LDL receptor and EGF precursor. Science (New York, N.Y.). 228: 893-5. PMID 3873704  0.84
1985 Lehrman MA, Schneider WJ, Südhof TC, Brown MS, Goldstein JL, Russell DW. Mutation in LDL receptor: Alu-Alu recombination deletes exons encoding transmembrane and cytoplasmic domains. Science (New York, N.Y.). 227: 140-6. PMID 3155573  0.84
1985 Südhof TC, Goldstein JL, Brown MS, Russell DW. The LDL receptor gene: a mosaic of exons shared with different proteins. Science (New York, N.Y.). 228: 815-22. PMID 2988123  0.84
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