Dean J. Burkin - Publications

Affiliations: 
Cell and Molecular Pharmacology and Physiology University of Nevada, Reno, Reno, NV, United States 
Area:
Molecular Biology, Neuroscience Biology

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Oliveira-Santos A, Dagda M, Wittmann J, Smalley R, Burkin DJ. Vemurafenib improves muscle histopathology in a mouse model of LAMA2-related congenital muscular dystrophy. Disease Models & Mechanisms. 16. PMID 37021539 DOI: 10.1242/dmm.049916  0.584
2022 Bugiardini E, Nunes AM, Oliveira-Santos A, Dagda M, Fontelonga TM, Barraza-Flores P, Pittman AM, Morrow JM, Parton M, Houlden H, Elliott PM, Syrris P, Maas RP, Akhtar MM, Küsters B, ... ... Burkin DJ, et al. Integrin α7 Mutations Are Associated With Adult-Onset Cardiac Dysfunction in Humans and Mice. Journal of the American Heart Association. 11: e026494. PMID 36444867 DOI: 10.1161/JAHA.122.026494  0.508
2022 Ba MA, Aiyuk A, Hernández K, Evasovic JM, Wuebbles RD, Burkin DJ, Singer CA. Transgenic overexpression of α7 integrin in smooth muscle attenuates allergen-induced airway inflammation in a murine model of asthma. Faseb Bioadvances. 4: 724-740. PMID 36349295 DOI: 10.1096/fba.2022-00050  0.466
2022 Oliveira-Santos A, Dagda M, Burkin DJ. Sunitinib inhibits STAT3 phosphorylation in cardiac muscle and prevents cardiomyopathy in the mdx mouse model of Duchenne muscular dystrophy. Human Molecular Genetics. PMID 35157045 DOI: 10.1093/hmg/ddac042  0.444
2020 Garg K, Mahmassani ZS, Dvoretskiy S, Valero MC, Huntsman HD, Lapp S, Wu YF, Hauschka MSSD, Burkin DJ, Boppart MD. Laminin-111 Improves the Anabolic Response to Mechanical Load in Aged Skeletal Muscle. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 33284954 DOI: 10.1093/gerona/glaa308  0.497
2020 Barraza-Flores P, Hermann HJ, Bates CR, Allen TG, Grunert TT, Burkin DJ. Human laminin-111 and laminin-211 protein therapy prevents muscle disease progression in an immunodeficient mouse model of LAMA2-CMD. Skeletal Muscle. 10: 18. PMID 32498713 DOI: 10.1186/s13395-020-00235-4  0.473
2020 Barraza-Flores P, Bukovec KE, Dagda M, Conner BW, Oliveira-Santos A, Grange RW, Burkin DJ. Laminin-111 protein therapy after disease onset slows muscle disease in a mouse model of Laminin-α2 related congenital muscular dystrophy. Human Molecular Genetics. PMID 32472139 DOI: 10.1093/Hmg/Ddaa104  0.596
2020 Jones TI, Chew GL, Barraza-Flores P, Schreier S, Ramirez M, Wuebbles RD, Burkin DJ, Bradley RK, Jones PL. Transgenic mice expressing tunable levels of DUX4 develop characteristic facioscapulohumeral muscular dystrophy-like pathophysiology ranging in severity. Skeletal Muscle. 10: 8. PMID 32278354 DOI: 10.1186/S13395-020-00227-4  0.497
2020 Barraza-Flores P, Bates CR, Oliveira-Santos A, Burkin DJ. Laminin and Integrin in LAMA2-Related Congenital Muscular Dystrophy: From Disease to Therapeutics. Frontiers in Molecular Neuroscience. 13: 1. PMID 32116540 DOI: 10.3389/Fnmol.2020.00001  0.628
2019 Barraza-Flores P, Fontelonga TM, Wuebbles RD, Hermann HJ, Nunes AM, Kornegay JN, Burkin DJ. Laminin-111 protein therapy enhances muscle regeneration and repair in the GRMD dog model of Duchenne muscular dystrophy. Human Molecular Genetics. PMID 31179490 DOI: 10.1093/Hmg/Ddz086  0.583
2019 Fontelonga TM, Jordan B, Nunes AM, Barraza-Flores P, Bolden N, Wuebbles RD, Greiner LM, Hu X, Ferrer M, Marugan J, Southall N, Burkin DJ. Sunitinib promotes myogenic regeneration and mitigates disease progression in the mdx mouse model of duchenne muscular dystrophy. Human Molecular Genetics. PMID 30806670 DOI: 10.1093/Hmg/Ddz044  0.607
2019 Wuebbles RD, Cruz V, Van Ry P, Barraza-Flores P, Brewer PD, Jones P, Burkin DJ. Human Galectin-1 Improves Sarcolemma Stability and Muscle Vascularization in the mdx Mouse Model of Duchenne Muscular Dystrophy. Molecular Therapy. Methods & Clinical Development. 13: 145-153. PMID 30788383 DOI: 10.1016/J.Omtm.2019.01.004  0.771
2017 Sarathy A, Nunes AM, Fontelonga TM, Ogata TY, Burkin DJ. Commentary: SU9516 increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy. Journal of Rare Diseases Research & Treatment. 2: 1-4. PMID 30882096  0.313
2017 Van Ry PM, Fontelonga TM, Barraza-Flores P, Sarathy A, Nunes AM, Burkin DJ. ECM-Related Myopathies and Muscular Dystrophies: Pros and Cons of Protein Therapies. Comprehensive Physiology. 7: 1519-1536. PMID 28915335 DOI: 10.1002/Cphy.C150033  0.821
2017 Willmann R, Gordish-Dressman H, Meinen S, Rüegg MA, Yu Q, Nagaraju K, Kumar A, Girgenrath M, Coffey CBM, Cruz V, Van Ry PM, Bogdanik L, Lutz C, Rutkowski A, Burkin DJ. Improving Reproducibility of Phenotypic Assessments in the DyW Mouse Model of Laminin-α2 Related Congenital Muscular Dystrophy. Journal of Neuromuscular Diseases. PMID 28550268 DOI: 10.3233/Jnd-170217  0.794
2017 Lewon M, Peters CM, Van Ry PM, Burkin DJ, Hunter KW, Hayes LJ. Evaluation of the behavioral characteristics of the mdx mouse model of duchenne muscular dystrophy through operant conditioning procedures. Behavioural Processes. 142: 8-20. PMID 28532665 DOI: 10.1016/J.Beproc.2017.05.012  0.731
2017 Sarathy A, Wuebbles RD, Fontelonga TM, Tarchione AR, Mathews Griner LA, Heredia DJ, Nunes AM, Duan S, Brewer PD, Van Ry T, Hennig GW, Gould TW, Dulcey AE, Wang A, Xu X, ... ... Burkin DJ, et al. SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28391962 DOI: 10.1016/J.Ymthe.2017.03.022  0.673
2017 Nunes AM, Wuebbles RD, Sarathy A, Fontelonga TM, Deries M, Burkin DJ, Thorsteinsdóttir S. Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy. Human Molecular Genetics. PMID 28334989 DOI: 10.1093/Hmg/Ddx083  0.678
2017 Doe J, Kaindl AM, Jijiwa M, de la Vega M, Hu H, Griffiths GS, Fontelonga TM, Barraza P, Cruz V, Van Ry P, Ramos JW, Burkin DJ, Matter ML. PTRH2 gene mutation causes progressive congenital skeletal muscle pathology. Human Molecular Genetics. PMID 28175314 DOI: 10.1093/Hmg/Ddx048  0.814
2015 Burkin DJ, Fontelonga TM. Mesothelioma cells breaking bad: loss of integrin α7 promotes cell motility and poor clinical outcomes in patients. The Journal of Pathology. 237: 282-4. PMID 26174987 DOI: 10.1002/Path.4587  0.323
2015 Van Ry PM, Wuebbles RD, Key M, Burkin DJ. Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular Dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 1285-97. PMID 26050991 DOI: 10.1038/Mt.2015.105  0.852
2015 Griffiths GS, Doe J, Jijiwa M, Van Ry P, Cruz V, de la Vega M, Ramos JW, Burkin DJ, Matter ML. Bit-1 is an essential regulator of myogenic differentiation. Journal of Cell Science. 128: 1707-17. PMID 25770104 DOI: 10.1242/Dev.125765  0.769
2015 Marshall JL, Oh J, Chou E, Lee JA, Holmberg J, Burkin DJ, Crosbie-Watson RH. Sarcospan integration into laminin-binding adhesion complexes that ameliorate muscular dystrophy requires utrophin and α7 integrin. Human Molecular Genetics. 24: 2011-22. PMID 25504048 DOI: 10.1093/Hmg/Ddu615  0.547
2015 van Ry PM, Wuebbles RD, Key M, Burkin DJ. Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular Dystrophy Molecular Therapy. DOI: 10.1038/mt.2015.105  0.483
2014 Van Ry PM, Minogue P, Hodges BL, Burkin DJ. Laminin-111 improves muscle repair in a mouse model of merosin-deficient congenital muscular dystrophy. Human Molecular Genetics. 23: 383-96. PMID 24009313 DOI: 10.1093/Hmg/Ddt428  0.854
2013 Hakim CH, Burkin DJ, Duan D. Alpha 7 integrin preserves the function of the extensor digitorum longus muscle in dystrophin-null mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 115: 1388-92. PMID 23990247 DOI: 10.1152/Japplphysiol.00602.2013  0.677
2013 Wuebbles RD, Sarathy A, Kornegay JN, Burkin DJ. Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy. Disease Models & Mechanisms. 6: 1175-84. PMID 23846963 DOI: 10.1242/Dmm.012211  0.631
2013 Rutkowski A, Bönnemann C, Brown S, Thorsteinsdóttir S, Dominov J, Ruegg MA, Matter ML, Guttridge D, Crosbie-Watson RH, Kardon G, Nagaraju K, Girgenrath M, Burkin DJ. Report on the Myomatrix Conference April 22-24, 2012, University of Nevada, Reno, Nevada, USA. Neuromuscular Disorders : Nmd. 23: 188-91. PMID 22800409 DOI: 10.1016/J.Nmd.2012.06.353  0.427
2013 Marshall J, Oh J, Chou E, Lee J, Allan K, Holmberg J, Burkin D, Crosbie-Watson R. P.1.16 Sarcospan amelioration of muscular dystrophy restores laminin binding and is dependent on α7β1 integrin and utrophin Neuromuscular Disorders. 23: 746. DOI: 10.1016/J.Nmd.2013.06.400  0.448
2012 Marshall JL, Chou E, Oh J, Kwok A, Burkin DJ, Crosbie-Watson RH. Dystrophin and utrophin expression require sarcospan: loss of α7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice. Human Molecular Genetics. 21: 4378-93. PMID 22798625 DOI: 10.1093/Hmg/Dds271  0.685
2012 Burkin DJ, Wuebbles RD. A molecular bandage for diseased muscle. Science Translational Medicine. 4: 139fs19. PMID 22723460 DOI: 10.1126/Scitranslmed.3004082  0.546
2012 Rooney JE, Knapp JR, Hodges BL, Wuebbles RD, Burkin DJ. Laminin-111 protein therapy reduces muscle pathology and improves viability of a mouse model of merosin-deficient congenital muscular dystrophy. The American Journal of Pathology. 180: 1593-602. PMID 22322301 DOI: 10.1016/J.Ajpath.2011.12.019  0.858
2011 Doe JA, Wuebbles RD, Allred ET, Rooney JE, Elorza M, Burkin DJ. Transgenic overexpression of the α7 integrin reduces muscle pathology and improves viability in the dy(W) mouse model of merosin-deficient congenital muscular dystrophy type 1A. Journal of Cell Science. 124: 2287-97. PMID 21652631 DOI: 10.1242/Jcs.083311  0.797
2011 Boppart MD, Burkin DJ, Kaufman SJ. Activation of AKT signaling promotes cell growth and survival in α7β1 integrin-mediated alleviation of muscular dystrophy. Biochimica Et Biophysica Acta. 1812: 439-46. PMID 21216283 DOI: 10.1016/J.Bbadis.2011.01.002  0.603
2010 Xiong D, Heyman NS, Airey J, Zhang M, Singer CA, Rawat S, Ye L, Evans R, Burkin DJ, Tian H, McCloskey DT, Valencik M, Britton FC, Duan D, Hume JR. Cardiac-specific, inducible ClC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice. Journal of Molecular and Cellular Cardiology. 48: 211-9. PMID 19615374 DOI: 10.1016/J.Yjmcc.2009.07.003  0.394
2010 Heyman N, Wuebbles R, Ye L, Duan D, Hume J, Burkin D. Cardioprotective Role For the CLC-3 Chloride Channel in the mdx Mouse Model of Duchenne Muscular Dystrophy Biophysical Journal. 98: 321a. DOI: 10.1016/J.Bpj.2009.12.1741  0.554
2009 Welser JV, Rooney JE, Cohen NC, Gurpur PB, Singer CA, Evans RA, Haines BA, Burkin DJ. Myotendinous junction defects and reduced force transmission in mice that lack alpha7 integrin and utrophin. The American Journal of Pathology. 175: 1545-54. PMID 19729483 DOI: 10.2353/Ajpath.2009.090052  0.833
2009 Rooney JE, Gurpur PB, Burkin DJ. Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 106: 7991-6. PMID 19416897 DOI: 10.1073/Pnas.0811599106  0.869
2009 Gurpur PB, Liu J, Burkin DJ, Kaufman SJ. Valproic acid activates the PI3K/Akt/mTOR pathway in muscle and ameliorates pathology in a mouse model of Duchenne muscular dystrophy. The American Journal of Pathology. 174: 999-1008. PMID 19179609 DOI: 10.2353/Ajpath.2009.080537  0.651
2009 Rooney JE, Gurpur PB, Yablonka-Reuveni Z, Burkin DJ. Laminin-111 restores regenerative capacity in a mouse model for alpha7 integrin congenital myopathy. The American Journal of Pathology. 174: 256-64. PMID 19074617 DOI: 10.2353/Ajpath.2009.080522  0.874
2009 Xiong D, Wang GX, Burkin DJ, Yamboliev IA, Singer CA, Rawat S, Scowen P, Evans R, Ye L, Hatton WJ, Tian H, Keller PS, McCloskey DT, Duan D, Hume JR. Cardiac-specific overexpression of the human short CLC-3 chloride channel isoform in mice. Clinical and Experimental Pharmacology & Physiology. 36: 386-93. PMID 18986326 DOI: 10.1111/J.1440-1681.2008.05069.X  0.39
2008 Boppart MD, Volker SE, Alexander N, Burkin DJ, Kaufman SJ. Exercise promotes alpha7 integrin gene transcription and protection of skeletal muscle. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R1623-30. PMID 18784336 DOI: 10.1152/Ajpregu.00089.2008  0.585
2008 Liu J, Burkin DJ, Kaufman SJ. Increasing alpha 7 beta 1-integrin promotes muscle cell proliferation, adhesion, and resistance to apoptosis without changing gene expression. American Journal of Physiology. Cell Physiology. 294: C627-40. PMID 18045857 DOI: 10.1152/Ajpcell.00329.2007  0.672
2007 Welser JV, Lange ND, Flintoff-Dye N, Burkin HR, Burkin DJ. Placental defects in alpha7 integrin null mice. Placenta. 28: 1219-28. PMID 17904217 DOI: 10.1016/J.Placenta.2007.08.002  0.818
2007 Welser JV, Lange N, Singer CA, Elorza M, Scowen P, Keef KD, Gerthoffer WT, Burkin DJ. Loss of the alpha7 integrin promotes extracellular signal-regulated kinase activation and altered vascular remodeling. Circulation Research. 101: 672-81. PMID 17704212 DOI: 10.1161/Circresaha.107.151415  0.797
2006 Rooney JE, Welser JV, Dechert MA, Flintoff-Dye NL, Kaufman SJ, Burkin DJ. Severe muscular dystrophy in mice that lack dystrophin and alpha7 integrin. Journal of Cell Science. 119: 2185-95. PMID 16684813 DOI: 10.1242/Jcs.02952  0.825
2006 Boppart MD, Burkin DJ, Kaufman SJ. Alpha7beta1-integrin regulates mechanotransduction and prevents skeletal muscle injury. American Journal of Physiology. Cell Physiology. 290: C1660-5. PMID 16421207 DOI: 10.1152/Ajpcell.00317.2005  0.598
2005 Flintoff-Dye NL, Welser J, Rooney J, Scowen P, Tamowski S, Hatton W, Burkin DJ. Role for the alpha7beta1 integrin in vascular development and integrity. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 234: 11-21. PMID 16003770 DOI: 10.1002/Dvdy.20462  0.813
2005 Burkin DJ, Wallace GQ, Milner DJ, Chaney EJ, Mulligan JA, Kaufman SJ. Transgenic expression of {alpha}7{beta}1 integrin maintains muscle integrity, increases regenerative capacity, promotes hypertrophy, and reduces cardiomyopathy in dystrophic mice. The American Journal of Pathology. 166: 253-63. PMID 15632017 DOI: 10.1016/S0002-9440(10)62249-3  0.618
2003 Li J, Rao H, Burkin D, Kaufman SJ, Wu C. The muscle integrin binding protein (MIBP) interacts with α7β1 integrin and regulates cell adhesion and laminin matrix deposition Developmental Biology. 261: 209-219. PMID 12941630 DOI: 10.1016/S0012-1606(03)00304-X  0.309
2001 Burkin DJ, Wallace GQ, Nicol KJ, Kaufman DJ, Kaufman SJ. Enhanced expression of the α7β1 integrin reduces muscular dystrophy and restores viability in dystrophic mice Journal of Cell Biology. 152: 1207-1218. PMID 11257121 DOI: 10.1083/jcb.152.6.1207  0.605
1999 Burkin DJ, Kaufman SJ. The α7β1 integrin in muscle development and disease Cell and Tissue Research. 296: 183-190. PMID 10199978 DOI: 10.1007/s004410051279  0.564
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