| Year |
Citation |
Score |
| 2020 |
Byun S, Seok S, Kim YC, Zhang Y, Yau P, Iwamori N, Xu HE, Ma J, Kemper B, Kemper JK. Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase. Nature Communications. 11: 807. PMID 32042044 DOI: 10.1038/S41467-020-14384-Z |
0.655 |
|
| 2019 |
Byun S, Jung H, Chen J, Kim YC, Kim DH, Kong B, Guo G, Kemper B, Kemper JK. Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling-activated Src maintains cholesterol levels and protects from atherosclerosis. The Journal of Biological Chemistry. PMID 30996006 DOI: 10.1074/Jbc.Ra119.008360 |
0.389 |
|
| 2018 |
Kim YC, Byun S, Seok S, Guo G, Xu HE, Kemper B, Kemper JK. Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption. Gastroenterology. PMID 30521806 DOI: 10.1053/J.Gastro.2018.11.061 |
0.327 |
|
| 2018 |
Byun S, Kim DH, Ryerson D, Kim YC, Sun H, Kong B, Yau P, Guo G, Xu HE, Kemper B, Kemper JK. Postprandial FGF19-induced phosphorylation by Src is critical for FXR function in bile acid homeostasis. Nature Communications. 9: 2590. PMID 29968724 DOI: 10.1038/S41467-018-04697-5 |
0.675 |
|
| 2018 |
Seok S, Kim YC, Byun S, Choi S, Xiao Z, Iwamori N, Zhang Y, Wang C, Ma J, Ge K, Kemper B, Kemper JK. Fasting-induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid β-oxidation. The Journal of Clinical Investigation. PMID 29911994 DOI: 10.1172/Jci97736 |
0.348 |
|
| 2018 |
Kim YC, Seok S, Byun S, Kong B, Zhang Y, Guo G, Xie W, Ma J, Kemper B, Kemper JK. AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle. Nature Communications. 9: 540. PMID 29416063 DOI: 10.1038/S41467-018-03060-Y |
0.319 |
|
| 2017 |
Kwon S, Seok S, Yau P, Li X, Kemper B, Kemper JK. Obesity and aging diminish SIRT1-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3. The Journal of Biological Chemistry. PMID 28808064 DOI: 10.1074/Jbc.M117.778720 |
0.62 |
|
| 2017 |
Choi SE, Kwon S, Seok S, Xiao Z, Lee KW, Kang Y, Li X, Shinoda K, Kajimura S, Kemper B, Kemper JK. Obesity-linked phosphorylation of SIRT1 by CK2 inhibits its nuclear localization and promotes fatty liver. Molecular and Cellular Biology. PMID 28533219 DOI: 10.1128/Mcb.00006-17 |
0.31 |
|
| 2017 |
Byun S, Kim YC, Zhang Y, Kong B, Guo G, Sadoshima J, Ma J, Kemper B, Kemper JK. A postprandial FGF19-SHP-LSD1 regulatory axis mediates epigenetic repression of hepatic autophagy. The Embo Journal. PMID 28446510 DOI: 10.15252/Embj.201695500 |
0.377 |
|
| 2016 |
Kim DH, Kwon S, Byun S, Xiao Z, Park S, Wu SY, Chiang CM, Kemper B, Kemper JK. Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis. Nature Communications. 7: 12179. PMID 27412403 DOI: 10.1038/Ncomms12179 |
0.425 |
|
| 2015 |
Kim YC, Byun S, Zhang Y, Seok S, Kemper B, Ma J, Kemper JK. Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2. Genome Biology. 16: 268. PMID 26634251 DOI: 10.1186/S13059-015-0835-6 |
0.482 |
|
| 2015 |
Fu T, Kim YC, Byun S, Kim DH, Seok S, Suino-Powell K, Xu HE, Kemper B, Kemper JK. FXR primes the liver for intestinal FGF15 signaling by transient induction of βKlotho. Molecular Endocrinology (Baltimore, Md.). me20151226. PMID 26505219 DOI: 10.1210/Me.2015-1226 |
0.41 |
|
| 2015 |
Kim YC, Fang S, Byun S, Seok S, Kemper B, Kemper JK. Farnesoid X receptor-induced lysine-specific histone demethylase reduces hepatic bile acid levels and protects the liver against bile acid toxicity. Hepatology (Baltimore, Md.). 62: 220-31. PMID 25545350 DOI: 10.1002/Hep.27677 |
0.42 |
|
| 2014 |
Seok S, Fu T, Choi SE, Li Y, Zhu R, Kumar S, Sun X, Yoon G, Kang Y, Zhong W, Ma J, Kemper B, Kemper JK. Transcriptional regulation of autophagy by an FXR-CREB axis. Nature. 516: 108-11. PMID 25383523 DOI: 10.1038/Nature13949 |
0.301 |
|
| 2011 |
Li B, Yau P, Kemper B.. Identification of cytochrome P450 2C2 protein complexes in mouse liver. Proteomics. 16: 3359. PMID 21751364 DOI: 10.1002/Pmic.201100001 |
0.644 |
|
| 2011 |
Szczesna-Skorupa E, Kemper B. Progesterone receptor membrane component 1 inhibits the activity of drug-metabolizing cytochromes P450 and binds to cytochrome P450 reductase. Molecular Pharmacology. 79: 340-350. PMID 21081644 DOI: 10.1124/Mol.110.068478 |
0.373 |
|
| 2008 |
Szczesna-Skorupa E, Kemper B. Proteasome inhibition compromises direct retention of cytochrome P450 2C2 in the endoplasmic reticulum. Experimental Cell Research. 314: 3221-3231. PMID 18755184 DOI: 10.1016/J.Yexcr.2008.08.003 |
0.354 |
|
| 2008 |
Szczesna-Skorupa E, Kemper B. Influence of protein-protein interactions on the cellular localization of cytochrome P450. Expert Opinion On Drug Metabolism & Toxicology. 4: 123-136. PMID 18248308 DOI: 10.1517/17425255.4.2.123 |
0.307 |
|
| 2007 |
Xia J, Liao L, Sarkar J, Matsumoto K, Reddy JK, Xu J, Kemper B. Redundant enhancement of mouse constitutive androstane receptor transactivation by p160 coactivator family members. Archives of Biochemistry and Biophysics. 468: 49-57. PMID 17950690 DOI: 10.1016/J.Abb.2007.09.005 |
0.38 |
|
| 2007 |
Xia J, Kemper B. Subcellular trafficking signals of constitutive androstane receptor: evidence for a nuclear export signal in the DNA-binding domain. Drug Metabolism and Disposition. 35: 1489-1494. PMID 17567731 DOI: 10.1124/Dmd.107.016493 |
0.454 |
|
| 2006 |
Zhang Q, Bae Y, Kemper JK, Kemper B. Analysis of multiple nuclear receptor binding sites for CAR/RXR in the phenobarbital responsive unit of CYP2B2. Archives of Biochemistry and Biophysics. 451: 119-27. PMID 16725103 DOI: 10.1016/J.Abb.2006.04.016 |
0.745 |
|
| 2006 |
Ozalp C, Szczesna-Skorupa E, Kemper B. Identification of membrane-contacting loops of the catalytic domain of cytochrome P450 2C2 by tryptophan fluorescence scanning. Biochemistry. 45: 4629-4637. PMID 16584198 DOI: 10.1021/Bi051372T |
0.304 |
|
| 2006 |
Szczesna-Skorupa E, Kemper B. BAP31 is involved in the retention of cytochrome P450 2C2 in the endoplasmic reticulum. Journal of Biological Chemistry. 281: 4142-4148. PMID 16332681 DOI: 10.1074/Jbc.M509522200 |
0.343 |
|
| 2005 |
Jia Y, Guo GL, Surapureddi S, Sarkar J, Qi C, Guo D, Xia J, Kashireddi P, Yu S, Cho YW, Rao MS, Kemper B, Ge K, Gonzalez FJ, Reddy JK. Transcription coactivator peroxisome proliferator-activated receptor-binding protein/mediator 1 deficiency abrogates acetaminophen hepatotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 102: 12531-6. PMID 16109766 DOI: 10.1073/Pnas.0506000102 |
0.462 |
|
| 2005 |
Ozalp C, Szczesna-Skorupa E, Kemper B. Bimolecular fluorescence complementation analysis of cytochrome p450 2c2, 2e1, and NADPH-cytochrome p450 reductase molecular interactions in living cells. Drug Metabolism and Disposition. 33: 1382-1390. PMID 15980100 DOI: 10.1124/Dmd.105.005538 |
0.317 |
|
| 2005 |
Xia J, Kemper B. Structural determinants of constitutive androstane receptor required for its glucocorticoid receptor interacting protein-1-mediated nuclear accumulation Journal of Biological Chemistry. 280: 7285-7293. PMID 15591315 DOI: 10.1074/Jbc.M409696200 |
0.476 |
|
| 2004 |
Kemper B. Structural basis for the role in protein folding of conserved proline-rich regions in cytochromes P450 Toxicology and Applied Pharmacology. 199: 305-315. PMID 15364546 DOI: 10.1016/J.Taap.2003.11.030 |
0.37 |
|
| 2004 |
Bae Y, Kemper JK, Kemper B. Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP). Dna and Cell Biology. 23: 81-91. PMID 15000748 DOI: 10.1089/104454904322759894 |
0.745 |
|
| 2004 |
Szczesna-Skorupa E, Chen CD, Liu H, Kemper B. Gene Expression Changes Associated with the Endoplasmic Reticulum Stress Response Induced by Microsomal Cytochrome P450 Overproduction Journal of Biological Chemistry. 279: 13953-13961. PMID 14718536 DOI: 10.1074/Jbc.M312170200 |
0.396 |
|
| 2003 |
Szczesna-Skorupa E, Mallah B, Kemper B. Fluorescence resonance energy transfer analysis of cytochromes P450 2C2 and 2E1 molecular interactions in living cells. Journal of Biological Chemistry. 278: 31269-31276. PMID 12766165 DOI: 10.1074/Jbc.M301489200 |
0.325 |
|
| 2003 |
Rivera-Rivera I, Kim J, Kemper B. Transcriptional analysis in vivo of the hepatic genes, Cyp2b9 and Cyp2b10, by intravenous administration of plasmid DNA in mice. Biochimica Et Biophysica Acta. 1619: 254-62. PMID 12573485 DOI: 10.1016/S0304-4165(02)00484-1 |
0.746 |
|
| 2002 |
Min G, Kemper JK, Kemper B. Glucocorticoid receptor-interacting protein 1 mediates ligand-independent nuclear translocation and activation of constitutive androstane receptor in vivo. The Journal of Biological Chemistry. 277: 26356-63. PMID 12000748 DOI: 10.1074/Jbc.M200051200 |
0.465 |
|
| 2001 |
Szczesna-Skorupa E, Kemper B. The Juxtamembrane Sequence of Cytochrome P-450 2C1 Contains an Endoplasmic Reticulum Retention Signal Journal of Biological Chemistry. 276: 45009-45014. PMID 11557755 DOI: 10.1074/Jbc.M104676200 |
0.364 |
|
| 2001 |
Doray B, Chen CD, Kemper B. N-terminal deletions and His-tag fusions dramatically affect expression of cytochrome p450 2C2 in bacteria. Archives of Biochemistry and Biophysics. 393: 143-153. PMID 11516171 DOI: 10.1006/Abbi.2001.2473 |
0.361 |
|
| 2001 |
Liu S, Rivera-Rivera I, Bredemeyer AJ, Kemper B. Functional analysis of the phenobarbital-responsive unit in rat CYP2B2 Biochemical Pharmacology. 62: 21-28. PMID 11377393 DOI: 10.1016/S0006-2952(01)00635-9 |
0.737 |
|
| 2001 |
Kim J, Min G, Kemper B. Chromatin assembly enhances binding to the CYP2B1 phenobarbital-responsive unit (PBRU) of nuclear factor-1, which binds simultaneously with constitutive androstane receptor (CAR)/retinoid X receptor (RXR) and enhances CAR/RXR-mediated activation of the PBRU. The Journal of Biological Chemistry. 276: 7559-67. PMID 11113125 DOI: 10.1074/Jbc.M008090200 |
0.459 |
|
| 2000 |
Szczesna-Skorupa E, Kemper BW. Endoplasmic reticulum retention determinants in the transmembrane and linker domains of cytochrome P450 2C1. Journal of Biological Chemistry. 275: 19409-19415. PMID 10781599 DOI: 10.1074/Jbc.M002394200 |
0.374 |
|
| 2000 |
Kim J, Rivera-Rivera I, Kemper B. Tissue-specific chromatin structure of the phenobarbital-responsive unit and proximal promoter of CYP2B1/2 and modulation by phenobarbital. Nucleic Acids Research. 28: 1126-32. PMID 10666453 DOI: 10.1093/Nar/28.5.1126 |
0.732 |
|
| 2000 |
Szczesna-Skorupa E, Chen CD, Kemper B. Cytochromes P450 2C1/2 and P450 2E1 are retained in the endoplasmic reticulum membrane by different mechanisms. Archives of Biochemistry and Biophysics. 374: 128-136. PMID 10666290 DOI: 10.1006/Abbi.1999.1628 |
0.344 |
|
| 1999 |
Doray B, Chen CD, Kemper B. Substitutions in the C-terminal portion of the catalytic domain partially reverse assembly defects introduced by mutations in the N-terminal linker sequence of cytochrome P450 2C2. Biochemistry. 38: 12180-12186. PMID 10508423 DOI: 10.1021/Bi9906266 |
0.358 |
|
| 1998 |
Szczesna-Skorupa E, Chen CIDI, Rogers S, Kemper B. Mobility of cytochrome P450 in the endoplasmic reticulum membrane Proceedings of the National Academy of Sciences of the United States of America. 95: 14793-14798. PMID 9843968 DOI: 10.1073/Pnas.95.25.14793 |
0.349 |
|
| 1998 |
Chen CD, Doray B, Kemper B. A conserved proline-rich sequence between the N-terminal signal-anchor and catalytic domains is required for assembly of functional cytochrome P450 2C2. Archives of Biochemistry and Biophysics. 350: 233-238. PMID 9473296 DOI: 10.1006/Abbi.1997.0524 |
0.381 |
|
| 1998 |
Kemper B. Regulation of Cytochrome P450 Gene Transcription by Phenobarbital Progress in Nucleic Acid Research and Molecular Biology. 61: 25-64. DOI: 10.1016/S0079-6603(08)60824-7 |
0.499 |
|
| 1997 |
Kim J, Kemper B. Phenobarbital alters protein binding to the CYP2B1/2 phenobarbital-responsive unit in native chromatin. The Journal of Biological Chemistry. 272: 29423-5. PMID 9367997 DOI: 10.1074/Jbc.272.47.29423 |
0.484 |
|
| 1996 |
Chen CD, Kemper B. Different Structural Requirements at Specific Proline Residue Positions in the Conserved Proline-rich Region of Cytochrome P450 2C2 Journal of Biological Chemistry. 271: 28607-28611. PMID 8910491 DOI: 10.1074/Jbc.271.45.28607 |
0.374 |
|
| 1996 |
Li H, Liu S, Kemper B. Sex- and tissue-specific expression of a cytochrome P450 2C2-luciferase transgene Molecular and Cellular Endocrinology. 120: 77-83. PMID 8809741 DOI: 10.1016/0303-7207(96)03823-3 |
0.377 |
|
| 1996 |
Park Y, Li H, Kemper B. Phenobarbital Induction Mediated by a Distal CYP2B2 Sequence in Rat Liver Transiently Transfected in Situ Journal of Biological Chemistry. 271: 23725-23728. PMID 8798596 DOI: 10.1074/Jbc.271.39.23725 |
0.468 |
|
| 1995 |
Ramarao MK, Straub P, Kemper B. Identification by in Vitro Mutagenesis of the Interaction of Two Segments of C2MstC1, a Chimera of Cytochromes P450 2C2 and P450 2C1 Journal of Biological Chemistry. 270: 1873-1880. PMID 7829524 DOI: 10.1074/Jbc.270.4.1873 |
0.347 |
|
| 1995 |
Chen D, Park Y, Kemper B. Differential protein binding and transcriptional activities of HNF-4 elements in three closely related CYP2C genes. Dna and Cell Biology. 13: 771-9. PMID 7772258 DOI: 10.1089/Dna.1994.13.771 |
0.473 |
|
| 1995 |
Szczesna-Skorupa E, Ahn K, Chen C, Doray B, Kemper B. The Cytoplasmic and N-terminal Transmembrane Domains of Cytochrome P450 Contain Independent Signals for Retention in the Endoplasmic Reticulum Journal of Biological Chemistry. 270: 24327-24333. PMID 7592644 DOI: 10.1074/Jbc.270.41.24327 |
0.353 |
|
| 1994 |
Straub P, Lloyd M, Johnson EF, Kemper B. Differential effects of mutations in substrate recognition site 1 of cytochrome P450 2C2 on lauric acid and progesterone hydroxylation. Biochemistry. 33: 8029-34. PMID 8025107 DOI: 10.1021/Bi00192A006 |
0.354 |
|
| 1994 |
Ahn K, Chen D, Kemper B. Inverse relationship of cotranslational translocation with the hydrophobic moment of the bovine preproparathyroid hormone signal sequence Biochimica Et Biophysica Acta. 1224: 459-462. PMID 7803504 DOI: 10.1016/0167-4889(94)90283-6 |
0.356 |
|
| 1993 |
Richardson TH, Hsu MH, Kronbach T, Barnes HJ, Chan G, Waterman MR, Kemper B, Johnson EF. Purification and characterization of recombinant-expressed cytochrome P450 2C3 from Escherichia coli: 2C3 encodes the 6β-hydroxylase deficient form of P450 3b Archives of Biochemistry and Biophysics. 300: 510-516. PMID 8380971 DOI: 10.1006/Abbi.1993.1069 |
0.312 |
|
| 1993 |
Szczesna-Skorupa E, Straub P, Kemper B. Deletion of a Conserved Tetrapeptide, PPGP, in P450 2C2 Results in Loss of Enzymatic Activity without a Change in Its Cellular Location Archives of Biochemistry and Biophysics. 304: 170-175. PMID 8323283 DOI: 10.1006/Abbi.1993.1335 |
0.396 |
|
| 1993 |
Straub P, Ramarao MK, Kemper B. Preference for aromatic substitutions at tryptophan-120, which is highly conserved and a potential mediator of electron transfer in cytochrome P450 2C2. Biochemical and Biophysical Research Communications. 197: 433-439. PMID 8267578 DOI: 10.1006/Bbrc.1993.2498 |
0.305 |
|
| 1993 |
Straub P, Johnson EF, Kemper B. Hydrophobic side chain requirements for lauric acid and progesterone hydroxylation at amino acid 113 in cytochrome P450 2C2, a potential determinant of substrate specificity. Archives of Biochemistry and Biophysics. 306: 521-7. PMID 8215458 DOI: 10.1006/Abbi.1993.1547 |
0.319 |
|
| 1991 |
Kronbach T, Kemper B, Johnson EF. A hypervariable region of P450IIC5 confers progesterone 21-hydroxylase activity to P450IIC1. Biochemistry. 30: 6097-102. PMID 2059619 DOI: 10.1021/Bi00239A003 |
0.373 |
|
| 1991 |
Szczesna-Skorupa E, Kemper B. Cell-free analysis of targeting of cytochrome P450 to microsomal membranes. Methods in Enzymology. 206: 64-75. PMID 1784247 DOI: 10.1016/0076-6879(91)06077-G |
0.329 |
|
| 1991 |
Kim JS, Kemper B. Differences in deoxyribonuclease I hypersensitive sites in phenobarbital-inducible and constitutive rabbit P450IIC genes. Biochemistry. 30: 10287-94. PMID 1718415 DOI: 10.1021/Bi00106A029 |
0.455 |
|
| 1989 |
Szczesna-Skorupa E, Kemper B. N-terminal basic amino acids are not required for translocation and processing of preproparathyroid hormone. Molecular Endocrinology. 3: 174-178. PMID 2563567 DOI: 10.1210/Mend-3-1-174 |
0.315 |
|
| 1987 |
Zhao J, Leighton JK, Kemper B. Characterization of rabbit cytochrome P450IIC4 cDNA and induction by phenobarbital of related hepatic mRNA levels Biochemical and Biophysical Research Communications. 146: 224-231. PMID 3453118 DOI: 10.1016/0006-291X(87)90714-5 |
0.386 |
|
| 1986 |
Szczesna-Skorupa E, Mead DA, Kemper B. The selection of the first AUG as the initiator of eucaryotic mRNAs translation is favored by a 5'-terminal cap group and a purine in the -3' position. Biochemical and Biophysical Research Communications. 140: 288-293. PMID 3778450 DOI: 10.1016/0006-291X(86)91088-0 |
0.332 |
|
| 1986 |
Kemper B. Molecular biology of parathyroid hormone. Critical Reviews in Biochemistry and Molecular Biology. 19: 353-379. PMID 3516570 DOI: 10.3109/10409238609082545 |
0.401 |
|
| 1986 |
Mead DA, Szczesna-Skorupa E, Kemper B. Single-stranded DNA 'blue' T7 promoter plasmids: a versatile tandem promoter system for cloning and protein engineering. Protein Engineering. 1: 67-74. PMID 3507689 DOI: 10.1093/Protein/1.1.67 |
0.372 |
|
| 1985 |
Mead DA, Skorupa ES, Kemper B. Single stranded DNA SP6 promoter plasmids for engineering mutant RNAs and proteins: synthesis of a 'stretched' preproparathyroid hormone. Nucleic Acids Research. 13: 1103-1118. PMID 3858795 DOI: 10.1093/Nar/13.4.1103 |
0.308 |
|
| 1984 |
Leighton JK, DeBrunner-Vossbrinck BA, Kemper B. Isolation and sequence analysis of three cloned cDNAs for rabbit liver proteins that are related to rabbit cytochrome P-450 (form 2), the major phenobarbital-inducible form. Biochemistry. 23: 204-210. PMID 6546520 DOI: 10.1021/Bi00297A005 |
0.404 |
|
| 1984 |
Weaver CA, Gordon DF, Kissil MS, Mead DA, Kemper B. Isolation and complete nucleotide sequence of the gene for bovine parathyroid hormone. Gene. 28: 319-29. PMID 6086460 DOI: 10.1016/0378-1119(84)90149-5 |
0.384 |
|
| 1982 |
Weaver CA, Gordon DF, Kemper B. Nucleotide sequence of bovine parathyroid hormone messenger RNA. Molecular and Cellular Endocrinology. 28: 411-24. PMID 6185374 DOI: 10.1016/0303-7207(82)90136-8 |
0.347 |
|
| 1981 |
Weaver CA, Gordon DF, Kemper B. Introduction by molecular cloning of artifactual inverted sequences at the 5' terminus of the sense strand of bovine parathyroid hormone cDNA. Proceedings of the National Academy of Sciences of the United States of America. 78: 4073-7. PMID 6170060 DOI: 10.1073/Pnas.78.7.4073 |
0.352 |
|
| 1980 |
Gordon DF, Kemper B. Synthesis, restriction analysis, and molecular cloning of near full length DNA complementary to bovine parathyroid hormone mRNA Nucleic Acids Research. 8: 5669-5683. PMID 6258149 DOI: 10.1093/Nar/8.23.5669 |
0.307 |
|
| 1978 |
Habener JF, Rosenblatt M, Kemper B, Kronenberg HM, Rich A, Potts JT. Pre-proparathyroid hormone; amino acid sequence, chemical synthesis, and some biological studies of the precursor region. Proceedings of the National Academy of Sciences of the United States of America. 75: 2616-20. PMID 96437 DOI: 10.1073/Pnas.75.6.2616 |
0.326 |
|
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