Donna J. Webb - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Neuroscience Biology

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Nielsen CP, Jernigan KK, Diggins NL, Webb DJ, MacGurn JA. USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification. Cell Reports. 28: 1074-1089.e5. PMID 31340145 DOI: 10.1016/j.celrep.2019.06.083  0.76
2018 Diggins NL, Kang H, Weaver A, Webb DJ. α5β1 integrin trafficking and Rac activation are regulated by APPL1 in a Rab5-dependent manner to inhibit cell migration. Journal of Cell Science. PMID 29361527 DOI: 10.1242/jcs.207019  0.76
2017 Diggins NL, Webb DJ. APPL1 is a multifunctional endosomal signaling adaptor protein. Biochemical Society Transactions. 45: 771-779. PMID 28620038 DOI: 10.1042/BST20160191  0.76
2016 Brown JA, Codreanu SG, Shi M, Sherrod SD, Markov DA, Neely MD, Britt CM, Hoilett OS, Reiserer RS, Samson PC, McCawley LJ, Webb DJ, Bowman AB, McLean JA, Wikswo JP. Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit. Journal of Neuroinflammation. 13: 306. PMID 27955696 DOI: 10.1186/s12974-016-0760-y  0.32
2015 Brown JA, Pensabene V, Markov DA, Allwardt V, Neely MD, Shi M, Britt CM, Hoilett OS, Yang Q, Brewer BM, Samson PC, McCawley LJ, May JM, Webb DJ, Li D, et al. Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor. Biomicrofluidics. 9: 054124. PMID 26576206 DOI: 10.1063/1.4934713  0.64
2015 Evans JC, Robinson CM, Shi M, Webb DJ. The guanine nucleotide exchange factor (GEF) Asef2 promotes dendritic spine formation via Rac activation and spinophilin-dependent targeting. The Journal of Biological Chemistry. 290: 10295-308. PMID 25750125 DOI: 10.1074/jbc.M114.605543  0.64
2015 Ao M, Brewer BM, Yang L, Franco Coronel OE, Hayward SW, Webb DJ, Li D. Stretching fibroblasts remodels fibronectin and alters cancer cell migration. Scientific Reports. 5: 8334. PMID 25660754 DOI: 10.1038/srep08334  0.64
2015 Broussard JA, Diggins NL, Hummel S, Georgescu W, Quaranta V, Webb DJ. Automated analysis of cell-matrix adhesions in 2D and 3D environments. Scientific Reports. 5: 8124. PMID 25630460 DOI: 10.1038/srep08124  0.64
2014 Jean L, Yang L, Majumdar D, Gao Y, Shi M, Brewer BM, Li D, Webb DJ. The Rho family GEF Asef2 regulates cell migration in three dimensional (3D) collagen matrices through myosin II. Cell Adhesion & Migration. 8: 460-7. PMID 25517435 DOI: 10.4161/19336918.2014.983778  0.64
2014 Evans JC, Hines KM, Forsythe JG, Erdogan B, Shi M, Hill S, Rose KL, McLean JA, Webb DJ. Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover. Journal of Proteome Research. 13: 3303-13. PMID 24874604 DOI: 10.1021/pr5001384  0.64
2014 Brewer BM, Shi M, Edd JF, Webb DJ, Li D. A microfluidic cell co-culture platform with a liquid fluorocarbon separator. Biomedical Microdevices. 16: 311-23. PMID 24420386 DOI: 10.1007/s10544-014-9834-8  0.64
2013 Alcendor DJ, Block FE, Cliffel DE, Daniels JS, Ellacott KL, Goodwin CR, Hofmeister LH, Li D, Markov DA, May JC, McCawley LJ, McLaughlin B, McLean JA, Niswender KD, Pensabene V, ... ... Webb DJ, et al. Neurovascular unit on a chip: implications for translational applications. Stem Cell Research & Therapy. 4: S18. PMID 24564885 DOI: 10.1186/scrt379  0.64
2013 Jean L, Majumdar D, Shi M, Hinkle LE, Diggins NL, Ao M, Broussard JA, Evans JC, Choma DP, Webb DJ. Activation of Rac by Asef2 promotes myosin IIdependent contractility to inhibit cell migration on type I collagen Journal of Cell Science. 126: 5585-5597. PMID 24144700 DOI: 10.1242/jcs.131060  0.64
2013 Lin WH, Hurley JT, Raines AN, Cheney RE, Webb DJ. Myosin X and its motorless isoform differentially modulate dendritic spine development by regulating trafficking and retention of vasodilator-stimulated phosphoprotein. Journal of Cell Science. 126: 4756-68. PMID 23943878 DOI: 10.1242/jcs.132969  0.92
2013 Shi M, Majumdar D, Gao Y, Brewer BM, Goodwin CR, McLean JA, Li D, Webb DJ. Glia co-culture with neurons in microfluidic platforms promotes the formation and stabilization of synaptic contacts. Lab On a Chip. 13: 3008-21. PMID 23736663 DOI: 10.1039/c3lc50249j  0.64
2013 Broussard JA, Rappaz B, Webb DJ, Brown CM. Fluorescence resonance energy transfer microscopy as demonstrated by measuring the activation of the serine/threonine kinase Akt. Nature Protocols. 8: 265-81. PMID 23306460 DOI: 10.1038/nprot.2012.147  0.64
2013 Webb DJ, Brown CM. Epi-fluorescence microscopy. Methods in Molecular Biology (Clifton, N.J.). 931: 29-59. PMID 23026996 DOI: 10.1007/978-1-62703-056-4_2  0.64
2012 Webb DJ, Brown CM, DeMali KA. Signals regulating adhesion dynamics. Journal of Signal Transduction. 2012: 785196. PMID 23346395 DOI: 10.1155/2012/785196  0.36
2012 Forsythe JG, Broussard JA, Lawrie JL, Kliman M, Jiao Y, Weiss SM, Webb DJ, McLean JA. Semitransparent nanostructured films for imaging mass spectrometry and optical microscopy. Analytical Chemistry. 84: 10665-70. PMID 23146026 DOI: 10.1021/ac3022967  0.64
2012 Broussard JA, Lin WH, Majumdar D, Anderson B, Eason B, Brown CM, Webb DJ. The endosomal adaptor protein APPL1 impairs the turnover of leading edge adhesions to regulate cell migration. Molecular Biology of the Cell. 23: 1486-99. PMID 22379109 DOI: 10.1091/mbc.E11-02-0124  0.64
2011 Gao Y, Majumdar D, Jovanovic B, Shaifer C, Lin PC, Zijlstra A, Webb DJ, Li D. A versatile valve-enabled microfluidic cell co-culture platform and demonstration of its applications to neurobiology and cancer biology. Biomedical Microdevices. 13: 539-48. PMID 21424383 DOI: 10.1007/s10544-011-9523-9  0.36
2011 Majumdar D, Nebhan CA, Hu L, Anderson B, Webb DJ. An APPL1/Akt signaling complex regulates dendritic spine and synapse formation in hippocampal neurons. Molecular and Cellular Neurosciences. 46: 633-44. PMID 21236345 DOI: 10.1016/j.mcn.2011.01.003  0.4
2011 Majumdar D, Gao Y, Li D, Webb DJ. Co-culture of neurons and glia in a novel microfluidic platform. Journal of Neuroscience Methods. 196: 38-44. PMID 21185867 DOI: 10.1016/j.jneumeth.2010.12.024  0.36
2010 Svitkina T, Lin WH, Webb DJ, Yasuda R, Wayman GA, Van Aelst L, Soderling SH. Regulation of the postsynaptic cytoskeleton: roles in development, plasticity, and disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14937-42. PMID 21068295 DOI: 10.1523/JNEUROSCI.4276-10.2010  0.64
2010 Lin WH, Nebhan CA, Anderson BR, Webb DJ. Vasodilator-stimulated phosphoprotein (VASP) induces actin assembly in dendritic spines to promote their development and potentiate synaptic strength. The Journal of Biological Chemistry. 285: 36010-20. PMID 20826790 DOI: 10.1074/jbc.M110.129841  0.64
2010 Gant-Branum RL, Broussard JA, Mahsut A, Webb DJ, McLean JA. Identification of phosphorylation sites within the signaling adaptor APPL1 by mass spectrometry. Journal of Proteome Research. 9: 1541-8. PMID 20095645 DOI: 10.1021/pr901043e  0.64
2009 Lin WH, Webb DJ. Actin and Actin-Binding Proteins: Masters of Dendritic Spine Formation, Morphology, and Function. The Open Neuroscience Journal. 3: 54-66. PMID 20717495 DOI: 10.2174/1874082000903020054  0.92
2009 Bristow JM, Sellers MH, Majumdar D, Anderson B, Hu L, Webb DJ. The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration. Journal of Cell Science. 122: 4535-46. PMID 19934221 DOI: 10.1242/jcs.053728  0.36
2008 Wegner AM, Nebhan CA, Hu L, Majumdar D, Meier KM, Weaver AM, Webb DJ. N-wasp and the arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapses. The Journal of Biological Chemistry. 283: 15912-20. PMID 18430734 DOI: 10.1074/jbc.M801555200  0.64
2008 Broussard JA, Webb DJ, Kaverina I. Asymmetric focal adhesion disassembly in motile cells. Current Opinion in Cell Biology. 20: 85-90. PMID 18083360 DOI: 10.1016/j.ceb.2007.10.009  0.64
2007 Peacock JG, Miller AL, Bradley WD, Rodriguez OC, Webb DJ, Koleske AJ. The Abl-related gene tyrosine kinase acts through p190RhoGAP to inhibit actomyosin contractility and regulate focal adhesion dynamics upon adhesion to fibronectin. Molecular Biology of the Cell. 18: 3860-72. PMID 17652459 DOI: 10.1091/mbc.E07-01-0075  0.64
2007 Webb DJ, Zhang H, Majumdar D, Horwitz AF. alpha5 integrin signaling regulates the formation of spines and synapses in hippocampal neurons. The Journal of Biological Chemistry. 282: 6929-35. PMID 17213186 DOI: 10.1074/jbc.M610981200  0.36
2006 Mayhew MW, Webb DJ, Kovalenko M, Whitmore L, Fox JW, Horwitz AF. Identification of protein networks associated with the PAK1-betaPIX-GIT1-paxillin signaling complex by mass spectrometry. Journal of Proteome Research. 5: 2417-23. PMID 16944954 DOI: 10.1021/pr060140t  0.64
2006 Lieu AS, Li JZ, Webb DJ, Hankins GR, Howng SL, Helm GA. Functions of G protein-coupled receptor kinase interacting protein 1 in human neuronal (NT2N) cells. Journal of Neurosurgery. 105: 103-10. PMID 16871884 DOI: 10.3171/jns.2006.105.1.103  0.64
2006 Webb DJ, Mayhew MW, Kovalenko M, Schroeder MJ, Jeffery ED, Whitmore L, Shabanowitz J, Hunt DF, Horwitz AF. Identification of phosphorylation sites in GIT1. Journal of Cell Science. 119: 2847-50. PMID 16825424 DOI: 10.1242/jcs03044  0.64
2006 Webb DJ, Kovalenko M, Whitmore L, Horwitz AF. Phosphorylation of serine 709 in GIT1 regulates protrusive activity in cells. Biochemical and Biophysical Research Communications. 346: 1284-8. PMID 16797488 DOI: 10.1016/j.bbrc.2006.06.036  0.64
2006 Nayal A, Webb DJ, Brown CM, Schaefer EM, Vicente-Manzanares M, Horwitz AR. Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics. The Journal of Cell Biology. 173: 587-9. PMID 16717130 DOI: 10.1083/jcb.200509075  0.64
2005 Webb DJ, Schroeder MJ, Brame CJ, Whitmore L, Shabanowitz J, Hunt DF, Horwitz AR. Paxillin phosphorylation sites mapped by mass spectrometry. Journal of Cell Science. 118: 4925-9. PMID 16254239 DOI: 10.1242/jcs.02563  0.64
2005 Vicente-Manzanares M, Webb DJ, Horwitz AR. Cell migration at a glance. Journal of Cell Science. 118: 4917-9. PMID 16254237 DOI: 10.1242/jcs.02662  0.64
2005 Schroeder MJ, Webb DJ, Shabanowitz J, Horwitz AF, Hunt DF. Methods for the detection of paxillin post-translational modifications and interacting proteins by mass spectrometry. Journal of Proteome Research. 4: 1832-41. PMID 16212439 DOI: 10.1021/pr0502020  0.64
2005 Bryce NS, Clark ES, Leysath JL, Currie JD, Webb DJ, Weaver AM. Cortactin promotes cell motility by enhancing lamellipodial persistence. Current Biology : Cb. 15: 1276-85. PMID 16051170 DOI: 10.1016/j.cub.2005.06.043  0.64
2005 Webb DJ, Zhang H, Horwitz AF. Cell migration: an overview. Methods in Molecular Biology (Clifton, N.J.). 294: 3-11. PMID 15576900  0.64
2004 Wiseman PW, Brown CM, Webb DJ, Hebert B, Johnson NL, Squier JA, Ellisman MH, Horwitz AF. Spatial mapping of integrin interactions and dynamics during cell migration by image correlation microscopy. Journal of Cell Science. 117: 5521-34. PMID 15479718 DOI: 10.1242/jcs.01416  0.64
2004 Nayal A, Webb DJ, Horwitz AF. Talin: an emerging focal point of adhesion dynamics. Current Opinion in Cell Biology. 16: 94-8. PMID 15037311 DOI: 10.1016/j.ceb.2003.11.007  0.64
2004 Webb DJ, Donais K, Whitmore LA, Thomas SM, Turner CE, Parsons JT, Horwitz AF. FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nature Cell Biology. 6: 154-61. PMID 14743221 DOI: 10.1038/ncb1094  0.64
2003 Webb DJ, Brown CM, Horwitz AF. Illuminating adhesion complexes in migrating cells: moving toward a bright future. Current Opinion in Cell Biology. 15: 614-20. PMID 14519397  0.36
2003 Webb DJ, Horwitz AF. New dimensions in cell migration. Nature Cell Biology. 5: 690-2. PMID 12894172 DOI: 10.1038/ncb0803-690  0.64
2002 Ma Z, Thomas KS, Webb DJ, Moravec R, Salicioni AM, Mars WM, Gonias SL. Regulation of Rac1 activation by the low density lipoprotein receptor-related protein. The Journal of Cell Biology. 159: 1061-70. PMID 12499359 DOI: 10.1083/jcb.200207070  0.64
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