Francesco Ramirez - Publications

Pharmacology and System Biology Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Neuroscience Biology

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Lee JJ, Galatioto J, Rao S, Ramirez F, Costa KD. Losartan Attenuates Degradation of Aorta and Lung Tissue Micromechanics in a Mouse Model of Severe Marfan Syndrome. Annals of Biomedical Engineering. PMID 27090893 DOI: 10.1007/s10439-016-1616-4  0.32
2016 Smaldone S, Bigarella CL, Del Solar M, Ghaffari S, Ramirez F. Fibrillin-1 microfibrils influence adult bone marrow hematopoiesis. Matrix Biology : Journal of the International Society For Matrix Biology. 52: 88-94. PMID 26610678 DOI: 10.1016/j.matbio.2015.11.006  0.56
2016 Smaldone S, Ramirez F. Fibrillin microfibrils in bone physiology. Matrix Biology : Journal of the International Society For Matrix Biology. 52: 191-7. PMID 26408953 DOI: 10.1016/j.matbio.2015.09.004  0.32
2015 Zilberberg L, Phoon CK, Robertson I, Dabovic B, Ramirez F, Rifkin DB. Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome. Proceedings of the National Academy of Sciences of the United States of America. 112: 14012-7. PMID 26494287 DOI: 10.1073/pnas.1507652112  0.32
2015 Smaldone S, Clayton NP, Del Solar M, Pascual-Gonzales G, Cheng SH, Wentworth BM, Schaffler MB, Ramirez F. Fibrillin-1 Regulates Skeletal Stem Cell Differentiation by Modulating TGFβ Activity Within the Marrow Niche. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26189658 DOI: 10.1002/jbmr.2598  0.32
2015 Sengle G, Carlberg V, Tufa SF, Charbonneau NL, Smaldone S, Carlson EJ, Ramirez F, Keene DR, Sakai LY. Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice. Plos Genetics. 11: e1005340. PMID 26114882 DOI: 10.1371/journal.pgen.1005340  0.32
2015 Ramirez F. Introduction to the mini-review series "Extracellular determinants of cell signaling". Matrix Biology : Journal of the International Society For Matrix Biology. 47: 1-2. PMID 25957948 DOI: 10.1016/j.matbio.2015.05.001  0.32
2015 Screen HR, Berk DE, Kadler KE, Ramirez F, Young MF. Tendon functional extracellular matrix. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 793-9. PMID 25640030 DOI: 10.1002/jor.22818  0.32
2015 Cook JR, Clayton NP, Carta L, Galatioto J, Chiu E, Smaldone S, Nelson CA, Cheng SH, Wentworth BM, Ramirez F. Dimorphic effects of transforming growth factor-β signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 911-7. PMID 25614286 DOI: 10.1161/ATVBAHA.114.305150  0.32
2014 Cook JR, Carta L, Bénard L, Chemaly ER, Chiu E, Rao SK, Hampton TG, Yurchenco P, Costa KD, Hajjar RJ, Ramirez F. Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome. The Journal of Clinical Investigation. 124: 1329-39. PMID 24531548 DOI: 10.1172/JCI71059  0.32
2014 Cook JR, Ramirez F. Clinical, diagnostic, and therapeutic aspects of the Marfan syndrome. Advances in Experimental Medicine and Biology. 802: 77-94. PMID 24443022 DOI: 10.1007/978-94-007-7893-1_6  0.52
2012 Pekar O, Benjamin S, Weidberg H, Smaldone S, Ramirez F, Horowitz M. EHD2 shuttles to the nucleus and represses transcription. The Biochemical Journal. 444: 383-94. PMID 22448906 DOI: 10.1042/BJ20111268  0.56
2012 Ramirez F, Rifkin DB. Is losartan the drug for all seasons? Current Opinion in Pharmacology. 12: 223-4. PMID 22445547 DOI: 10.1016/j.coph.2012.02.007  0.32
2012 Cook JR, Smaldone S, Cozzolino C, del Solar M, Lee-Arteaga S, Nistala H, Ramirez F. Generation of Fbn1 conditional null mice implicates the extracellular microfibrils in osteoprogenitor recruitment. Genesis (New York, N.Y. : 2000). 50: 635-41. PMID 22374917 DOI: 10.1002/dvg.22022  0.56
2011 Smaldone S, Carta L, Ramirez F. Establishment of fibrillin-deficient osteoprogenitor cell lines identifies molecular abnormalities associated with extracellular matrix perturbation of osteogenic differentiation. Cell and Tissue Research. 344: 511-7. PMID 21538048 DOI: 10.1007/s00441-011-1167-9  0.56
2011 Arteaga-Solis E, Sui-Arteaga L, Kim M, Schaffler MB, Jepsen KJ, Pleshko N, Ramirez F. Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils. Matrix Biology : Journal of the International Society For Matrix Biology. 30: 188-94. PMID 21440062 DOI: 10.1016/j.matbio.2011.03.004  0.32
2011 Smaldone S, Olivieri J, Gusella GL, Moroncini G, Gabrielli A, Ramirez F. Ha-Ras stabilization mediates pro-fibrotic signals in dermal fibroblasts. Fibrogenesis & Tissue Repair. 4: 8. PMID 21362163 DOI: 10.1186/1755-1536-4-8  0.56
2011 Caiazzo M, Colucci-D'Amato L, Volpicelli F, Speranza L, Petrone C, Pastore L, Stifani S, Ramirez F, Bellenchi GC, di Porzio U. Krüppel-like factor 7 is required for olfactory bulb dopaminergic neuron development. Experimental Cell Research. 317: 464-73. PMID 21093432 DOI: 10.1016/j.yexcr.2010.11.006  0.32
2010 Olivieri J, Smaldone S, Ramirez F. Fibrillin assemblies: extracellular determinants of tissue formation and fibrosis. Fibrogenesis & Tissue Repair. 3: 24. PMID 21126338 DOI: 10.1186/1755-1536-3-24  0.56
2010 Nistala H, Lee-Arteaga S, Carta L, Cook JR, Smaldone S, Siciliano G, Rifkin AN, Dietz HC, Rifkin DB, Ramirez F. Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome. Human Molecular Genetics. 19: 4790-8. PMID 20871099 DOI: 10.1093/hmg/ddq409  0.32
2010 Nistala H, Lee-Arteaga S, Smaldone S, Siciliano G, Carta L, Ono RN, Sengle G, Arteaga-Solis E, Levasseur R, Ducy P, Sakai LY, Karsenty G, Ramirez F. Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation. The Journal of Cell Biology. 190: 1107-21. PMID 20855508 DOI: 10.1083/jcb.201003089  0.32
2010 Nistala H, Lee-Arteaga S, Smaldone S, Siciliano G, Ramirez F. Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production. The Journal of Biological Chemistry. 285: 34126-33. PMID 20729550 DOI: 10.1074/jbc.M110.125328  0.56
2010 Cook JR, Nistala H, Ramirez F. Drug-based therapies for vascular disease in Marfan syndrome: from mouse models to human patients. The Mount Sinai Journal of Medicine, New York. 77: 366-73. PMID 20687182 DOI: 10.1002/msj.20200  0.56
2010 Caiazzo M, Colucci-D'Amato L, Esposito MT, Parisi S, Stifani S, Ramirez F, di Porzio U. Transcription factor KLF7 regulates differentiation of neuroectodermal and mesodermal cell lineages. Experimental Cell Research. 316: 2365-76. PMID 20580711 DOI: 10.1016/j.yexcr.2010.05.021  0.32
2010 Charbonneau NL, Carlson EJ, Tufa S, Sengle G, Manalo EC, Carlberg VM, Ramirez F, Keene DR, Sakai LY. In vivo studies of mutant fibrillin-1 microfibrils. The Journal of Biological Chemistry. 285: 24943-55. PMID 20529844 DOI: 10.1074/jbc.M110.130021  0.32
2010 Charbonneau NL, Jordan CD, Keene DR, Lee-Arteaga S, Dietz HC, Rifkin DB, Ramirez F, Sakai LY. Microfibril structure masks fibrillin-2 in postnatal tissues. The Journal of Biological Chemistry. 285: 20242-51. PMID 20404337 DOI: 10.1074/jbc.M109.087031  0.32
2010 Nistala H, Lee-Arteaga S, Siciliano G, Smaldone S, Ramirez F. Extracellular regulation of transforming growth factor beta and bone morphogenetic protein signaling in bone. Annals of the New York Academy of Sciences. 1192: 253-6. PMID 20392244 DOI: 10.1111/j.1749-6632.2009.05350.x  0.56
2010 Chernousov MA, Baylor K, Stahl RC, Stecker MM, Sakai LY, Lee-Arteaga S, Ramirez F, Carey DJ. Fibrillin-2 is dispensable for peripheral nerve development, myelination and regeneration. Matrix Biology : Journal of the International Society For Matrix Biology. 29: 357-68. PMID 20188829 DOI: 10.1016/j.matbio.2010.02.006  0.32
2010 Su J, Gorse K, Ramirez F, Fox MA. Collagen XIX is expressed by interneurons and contributes to the formation of hippocampal synapses. The Journal of Comparative Neurology. 518: 229-53. PMID 19937713 DOI: 10.1002/cne.22228  0.32
2010 Ramirez F, Sakai LY. Biogenesis and function of fibrillin assemblies. Cell and Tissue Research. 339: 71-82. PMID 19513754 DOI: 10.1007/s00441-009-0822-x  0.32
2009 Carta L, Wagenseil JE, Knutsen RH, Mariko B, Faury G, Davis EC, Starcher B, Mecham RP, Ramirez F. Discrete contributions of elastic fiber components to arterial development and mechanical compliance. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 2083-9. PMID 19850904 DOI: 10.1161/ATVBAHA.109.193227  0.32
2009 Ramirez F, Rifkin DB. Extracellular microfibrils: contextual platforms for TGFbeta and BMP signaling. Current Opinion in Cell Biology. 21: 616-22. PMID 19525102 DOI: 10.1016/  0.32
2009 Ono RN, Sengle G, Charbonneau NL, Carlberg V, Bächinger HP, Sasaki T, Lee-Arteaga S, Zilberberg L, Rifkin DB, Ramirez F, Chu ML, Sakai LY. Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites. The Journal of Biological Chemistry. 284: 16872-81. PMID 19349279 DOI: 10.1074/jbc.M809348200  0.32
2009 Ramirez F, Dietz HC. Extracellular microfibrils in vertebrate development and disease processes. The Journal of Biological Chemistry. 284: 14677-81. PMID 19188363 DOI: 10.1074/jbc.R900004200  0.32
2009 Carta L, Smaldone S, Zilberberg L, Loch D, Dietz HC, Rifkin DB, Ramirez F. p38 MAPK is an early determinant of promiscuous Smad2/3 signaling in the aortas of fibrillin-1 (Fbn1)-null mice. The Journal of Biological Chemistry. 284: 5630-6. PMID 19109253 DOI: 10.1074/jbc.M806962200  0.32
2009 Dabovic B, Chen Y, Choi J, Vassallo M, Dietz HC, Ramirez F, von Melchner H, Davis EC, Rifkin DB. Dual functions for LTBP in lung development: LTBP-4 independently modulates elastogenesis and TGF-beta activity. Journal of Cellular Physiology. 219: 14-22. PMID 19016471 DOI: 10.1002/jcp.21643  0.32
2008 Pearson GD, Devereux R, Loeys B, Maslen C, Milewicz D, Pyeritz R, Ramirez F, Rifkin D, Sakai L, Svensson L, Wessels A, Van Eyk J, Dietz HC. Report of the National Heart, Lung, and Blood Institute and National Marfan Foundation Working Group on research in Marfan syndrome and related disorders. Circulation. 118: 785-91. PMID 18695204 DOI: 10.1161/CIRCULATIONAHA.108.783753  0.32
2008 Ramirez F, Carta L, Lee-Arteaga S, Liu C, Nistala H, Smaldone S. Fibrillin-rich microfibrils - Structural and instructive determinants of mammalian development and physiology Connective Tissue Research. 49: 1-6. PMID 18293172 DOI: 10.1080/03008200701820708  0.32
2008 Xiong W, Knispel RA, Dietz HC, Ramirez F, Baxter BT. Doxycycline delays aneurysm rupture in a mouse model of Marfan syndrome. Journal of Vascular Surgery. 47: 166-72; discussion 1. PMID 18178469 DOI: 10.1016/j.jvs.2007.09.016  0.32
2007 Ramirez F, Dietz HC. Fibrillin-rich microfibrils: Structural determinants of morphogenetic and homeostatic events. Journal of Cellular Physiology. 213: 326-30. PMID 17708531 DOI: 10.1002/jcp.21189  0.32
2007 Ramirez F, Dietz HC. Marfan syndrome: from molecular pathogenesis to clinical treatment. Current Opinion in Genetics & Development. 17: 252-8. PMID 17467262 DOI: 10.1016/j.gde.2007.04.006  0.32
2007 Cohn RD, van Erp C, Habashi JP, Soleimani AA, Klein EC, Lisi MT, Gamradt M, ap Rhys CM, Holm TM, Loeys BL, Ramirez F, Judge DP, Ward CW, Dietz HC. Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states. Nature Medicine. 13: 204-10. PMID 17237794 DOI: 10.1038/nm1536  0.32
2007 Jones KB, Sponseller PD, Erkula G, Sakai L, Ramirez F, Dietz HC, Kost-Byerly S, Bridwell KH, Sandell L. Symposium on the musculoskeletal aspects of Marfan syndrome: meeting report and state of the science. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 25: 413-22. PMID 17143900 DOI: 10.1002/jor.20314  0.32
2007 Tanaka S, Ramirez F. The first intron of the human alpha2(I) collagen gene (COL1A2) contains a novel interferon-gamma responsive element. Matrix Biology : Journal of the International Society For Matrix Biology. 26: 185-9. PMID 17142024 DOI: 10.1016/j.matbio.2006.10.009  0.32
2006 Smaldone S, Ramirez F. Multiple pathways regulate intracellular shuttling of MoKA, a co-activator of transcription factor KLF7. Nucleic Acids Research. 34: 5060-8. PMID 16990251 DOI: 10.1093/nar/gkl659  0.32
2006 Habashi JP, Judge DP, Holm TM, Cohn RD, Loeys BL, Cooper TK, Myers L, Klein EC, Liu G, Calvi C, Podowski M, Neptune ER, Halushka MK, Bedja D, Gabrielson K, ... ... Ramirez F, et al. Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. Science (New York, N.Y.). 312: 117-21. PMID 16601194 DOI: 10.1126/science.1124287  0.32
2006 Carta L, Pereira L, Arteaga-Solis E, Lee-Arteaga SY, Lenart B, Starcher B, Merkel CA, Sukoyan M, Kerkis A, Hazeki N, Keene DR, Sakai LY, Ramirez F. Fibrillins 1 and 2 perform partially overlapping functions during aortic development. The Journal of Biological Chemistry. 281: 8016-23. PMID 16407178 DOI: 10.1074/jbc.M511599200  0.32
2005 Dietz HC, Loeys B, Carta L, Ramirez F. Recent progress towards a molecular understanding of Marfan syndrome. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 139: 4-9. PMID 16273535 DOI: 10.1002/ajmg.c.30068  0.32
2005 Laub F, Lei L, Sumiyoshi H, Kajimura D, Dragomir C, Smaldone S, Puche AC, Petros TJ, Mason C, Parada LF, Ramirez F. Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system. Molecular and Cellular Biology. 25: 5699-711. PMID 15964824 DOI: 10.1128/MCB.25.13.5699-5711.2005  0.32
2004 Ramirez F, Dietz HC. Therapy insight: aortic aneurysm and dissection in Marfan's syndrome. Nature Clinical Practice. Cardiovascular Medicine. 1: 31-6. PMID 16265257 DOI: 10.1038/ncpcardio0020  0.32
2004 Ramirez F, Sakai LY, Dietz HC, Rifkin DB. Fibrillin microfibrils: multipurpose extracellular networks in organismal physiology. Physiological Genomics. 19: 151-4. PMID 15466717 DOI: 10.1152/physiolgenomics.00092.2004  0.32
2004 Smaldone S, Laub F, Else C, Dragomir C, Ramirez F. Identification of MoKA, a novel F-box protein that modulates Krüppel-like transcription factor 7 activity. Molecular and Cellular Biology. 24: 1058-69. PMID 14729953 DOI: 10.1128/MCB.24.3.1058-1069.2004  0.56
2003 De Graeve F, Smaldone S, Laub F, Mlodzik M, Bhat M, Ramirez F. Identification of the Drosophila progenitor of mammalian Krüppel-like factors 6 and 7 and a determinant of fly development. Gene. 314: 55-62. PMID 14527717 DOI: 10.1016/S0378-1119(03)00720-0  0.32
2003 Ramirez F, Rifkin DB. Cell signaling events: a view from the matrix. Matrix Biology : Journal of the International Society For Matrix Biology. 22: 101-7. PMID 12782137 DOI: 10.1016/S0945-053X(03)00002-7  0.32
2003 Itskovich VV, Lieb M, Aguinaldo JG, Samber DD, Ramirez F, Fayad ZA. Magnetic resonance microscopy quantifies the disease progression in Marfan syndrome mice. Journal of Magnetic Resonance Imaging : Jmri. 17: 435-9. PMID 12655582 DOI: 10.1002/jmri.10279  0.32
2003 Neptune ER, Frischmeyer PA, Arking DE, Myers L, Bunton TE, Gayraud B, Ramirez F, Sakai LY, Dietz HC. Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome. Nature Genetics. 33: 407-11. PMID 12598898 DOI: 10.1038/ng1116  0.32
2002 Sakai LY, Byers PH, Ramirez F. A report on the 3rd Workshop on Heritable Disorders of Connective Tissue. Matrix Biology : Journal of the International Society For Matrix Biology. 21: 7-13. PMID 11827787 DOI: 10.1016/S0945-053X(01)00178-0  0.32
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