| Year |
Citation |
Score |
| 2024 |
Baxter RM, Cabrera-Martinez B, Ghosh T, Rester C, Moreno MG, Borko TL, Selva S, Fleischer CL, Haakonsen N, Mayher A, Bowhay E, Evans C, Miller TM, Huey L, McWilliams J, ... ... Kedl RM, et al. SARS-CoV-2 Vaccine-Elicited Immunity after B Cell Depletion in Multiple Sclerosis. Immunohorizons. 8: 254-268. PMID 38483384 DOI: 10.4049/immunohorizons.2300108 |
0.506 |
|
| 2023 |
Fry T, DeGolier K, Danis E, D'Antonio M, Cimons J, Yarnell M, Kedl R, Kohler M, Scott-Browne J. Antigen experience history directs distinct functional states of CD8+ CAR T cells during the anti-leukemia response. Research Square. PMID 38196657 DOI: 10.21203/rs.3.rs-3712137/v1 |
0.465 |
|
| 2023 |
Borko TL, Baxter R, Cabrera-Martinez B, Thiruppathi E, Sabalza M, Venkataraman I, Selva S, Rester C, Sillau S, Pastula DM, Bennett JL, Alvarez E, Gross R, Shah A, Kammeyer R, ... ... Kedl RM, et al. SARS-CoV-2 mRNA vaccination induces an antigen-specific T cell response correlating with plasma interferon-gamma in B cell depleted patients. Journal of Neuroimmunology. 383: 578192. PMID 37666038 DOI: 10.1016/j.jneuroim.2023.578192 |
0.491 |
|
| 2023 |
Ivanova DL, Thompson SB, Klarquist J, Harbell MG, Kilgore AM, Lasda EL, Hesselberth JR, Hunter CA, Kedl RM. Vaccine adjuvant-elicited CD8 T cell immunity is co-dependent on T-bet and FOXO1. Cell Reports. 42: 112911. PMID 37516968 DOI: 10.1016/j.celrep.2023.112911 |
0.503 |
|
| 2023 |
Piper M, Hoen M, Darragh LB, Knitz MW, Nguyen D, Gadwa J, Durini G, Karakoc I, Grier A, Neupert B, Van Court B, Abdelazeem KNM, Yu J, Olimpo NA, Corbo S, ... ... Kedl RM, et al. Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis. Cancer Cell. PMID 37116489 DOI: 10.1016/j.ccell.2023.04.001 |
0.342 |
|
| 2022 |
Pritchard GH, Phan AT, Christian DA, Blain TJ, Fang Q, Johnson J, Roy NH, Shallberg L, Kedl RM, Hunter CA. Early T-bet promotes LFA1 upregulation required for CD8+ effector and memory T cell development. The Journal of Experimental Medicine. 220. PMID 36445307 DOI: 10.1084/jem.20191287 |
0.507 |
|
| 2022 |
Christian DA, Adams TA, Shallberg LA, Phan AT, Smith TE, Abraha M, Perry J, Ruthel G, Clark JT, Pritchard GH, Aronson LR, Gossa S, McGavern DB, Kedl RM, Hunter CA. cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory. Science Immunology. 7: eabq7432. PMID 36179012 DOI: 10.1126/sciimmunol.abq7432 |
0.564 |
|
| 2022 |
Camp FA, Brunetti TM, Williams MM, Christenson JL, Sreekanth V, Costello JC, Hay ZLZ, Kedl RM, Richer JK, Slansky JE. Antigens Expressed by Breast Cancer Cells Undergoing EMT Stimulate Cytotoxic CD8 T Cell Immunity. Cancers. 14. PMID 36139558 DOI: 10.3390/cancers14184397 |
0.43 |
|
| 2022 |
Waldman MM, Rahkola JT, Sigler AL, Chung JW, Willett BAS, Kedl RM, Friedman RS, Jacobelli J. Ena/VASP Protein-Mediated Actin Polymerization Contributes to Naïve CD8 T Cell Activation and Expansion by Promoting T Cell-APC Interactions . Frontiers in Immunology. 13: 856977. PMID 35757762 DOI: 10.3389/fimmu.2022.856977 |
0.415 |
|
| 2022 |
Kansler ER, Dadi S, Krishna C, Nixon BG, Stamatiades EG, Liu M, Kuo F, Zhang J, Zhang X, Capistrano K, Blum KA, Weiss K, Kedl RM, Cui G, Ikuta K, et al. Cytotoxic innate lymphoid cells sense cancer cell-expressed interleukin-15 to suppress human and murine malignancies. Nature Immunology. PMID 35618834 DOI: 10.1038/s41590-022-01213-2 |
0.302 |
|
| 2022 |
Torphy RJ, Sun Y, Lin R, Caffrey-Carr A, Fujiwara Y, Ho F, Miller EN, McCarter MD, Lyons TR, Schulick RD, Kedl RM, Zhu Y. GPR182 limits antitumor immunity via chemokine scavenging in mouse melanoma models. Nature Communications. 13: 97. PMID 35013216 DOI: 10.1038/s41467-021-27658-x |
0.356 |
|
| 2021 |
Suwanpradid J, Lee MJ, Hoang P, Kwock J, Floyd LP, Smith JS, Yin Z, Atwater AR, Rajagopal S, Kedl RM, Corcoran DL, Zhang JY, MacLeod AS. IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses. Frontiers in Immunology. 12: 713304. PMID 34659203 DOI: 10.3389/fimmu.2021.713304 |
0.372 |
|
| 2021 |
Klarquist J, Cross EW, Thompson SB, Willett B, Aldridge DL, Caffrey-Carr AK, Xu Z, Hunter CA, Getahun A, Kedl RM. B cells promote CD8 T cell primary and memory responses to subunit vaccines. Cell Reports. 36: 109591. PMID 34433030 DOI: 10.1016/j.celrep.2021.109591 |
0.523 |
|
| 2021 |
Davenport BJ, Morrison TE, Kedl RM, Klarquist J. Conserved and Novel Mouse CD8 T Cell Epitopes within SARS-CoV-2 Spike Receptor Binding Domain Protein Identified following Subunit Vaccination. Journal of Immunology (Baltimore, Md. : 1950). 206: 2503-2507. PMID 33972373 DOI: 10.4049/jimmunol.2100195 |
0.462 |
|
| 2021 |
Lee W, Kingstad-Bakke B, Kedl RM, Kawaoka Y, Suresh M. CCR2 Regulates Vaccine-Induced Mucosal T-Cell Memory to Influenza A Virus. Journal of Virology. PMID 33952647 DOI: 10.1128/JVI.00530-21 |
0.513 |
|
| 2021 |
Lee W, Kingstad-Bakke B, Kedl RM, Kawaoka Y, Suresh M. CCR2 Regulates Vaccine-Induced Mucosal T-Cell Memory to Influenza A Virus. Biorxiv : the Preprint Server For Biology. PMID 33791695 DOI: 10.1101/2021.03.24.436901 |
0.535 |
|
| 2021 |
Burrack AL, Rollins MR, Spartz EJ, Mesojednik TD, Schmiechen ZC, Raynor JF, Wang IX, Kedl RM, Stromnes IM. CD40 Agonist Overcomes T Cell Exhaustion Induced by Chronic Myeloid Cell IL-27 Production in a Pancreatic Cancer Preclinical Model. Journal of Immunology (Baltimore, Md. : 1950). PMID 33558374 DOI: 10.4049/jimmunol.2000765 |
0.388 |
|
| 2020 |
Marinaik CB, Kingstad-Bakke B, Lee W, Hatta M, Sonsalla M, Larsen A, Neldner B, Gasper DJ, Kedl RM, Kawaoka Y, Suresh M. Programming Multifaceted Pulmonary T Cell Immunity by Combination Adjuvants. Cell Reports. Medicine. 1: 100095. PMID 32984856 DOI: 10.1016/j.xcrm.2020.100095 |
0.554 |
|
| 2020 |
Eberlein J, Davenport B, Nguyen TT, Victorino F, Jhun K, van der Heide V, Kuleshov M, Ma'ayan A, Kedl R, Homann D. Chemokine Signatures of Pathogen-Specific T Cells I: Effector T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 32948687 DOI: 10.4049/Jimmunol.2000253 |
0.576 |
|
| 2020 |
Davenport B, Eberlein J, Nguyen TT, Victorino F, van der Heide V, Kuleshov M, Ma'ayan A, Kedl R, Homann D. Chemokine Signatures of Pathogen-Specific T Cells II: Memory T Cells in Acute and Chronic Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 32948682 DOI: 10.4049/Jimmunol.2000254 |
0.519 |
|
| 2020 |
Davenport BJ, Bullock C, McCarthy MK, Hawman DW, Murphy KM, Kedl RM, Diamond MS, Morrison TE. Chikungunya virus evades antiviral CD8 T cell responses to establish persistent infection in joint-associated tissues. Journal of Virology. PMID 32102875 DOI: 10.1128/Jvi.02036-19 |
0.577 |
|
| 2020 |
Burrack AL, Rollins MR, Spartz EJ, Raynor JF, Wang I, Mitchell J, Kaisho T, Fife B, Kedl R, Shen S, Stromnes IM. Abstract NG12: Mechanisms governing efficacy of combination CD40 agonist and anti-PD-L1 in pancreatic ductal adenocarcinoma Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Ng12 |
0.507 |
|
| 2019 |
Kilgore AM, Pennock ND, Kedl RM. cDC1 IL-27p28 Production Predicts Vaccine-Elicited CD8 T Cell Memory and Protective Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 31871021 DOI: 10.4049/Jimmunol.1901357 |
0.603 |
|
| 2019 |
Thompson EA, Darrah PA, Foulds KE, Hoffer E, Caffrey-Carr A, Norenstedt S, Perbeck L, Seder RA, Kedl RM, Loré K. Monocytes Acquire the Ability to Prime Tissue-Resident T Cells via IL-10-Mediated TGF-β Release. Cell Reports. 28: 1127-1135.e4. PMID 31365858 DOI: 10.1016/J.Celrep.2019.06.087 |
0.544 |
|
| 2019 |
Fernandez IZ, Baxter RM, Garcia-Perez JE, Vendrame E, Ranganath T, Kong DS, Lundquist K, Nguyen T, Ogolla S, Black J, Galambos C, Gumbart JC, Dawany N, Kelsen JR, de Zoeten EF, ... ... Kedl RM, et al. Correction: A novel human mutation results in T and NK cell-driven immune dysregulation. The Journal of Experimental Medicine. PMID 31088899 DOI: 10.1084/Jem.2018201505102019C |
0.445 |
|
| 2019 |
Fernandez IZ, Baxter RM, Garcia-Perez JE, Vendrame E, Ranganath T, Kong DS, Lundquist K, Nguyen T, Ogolla S, Black J, Galambos C, Gumbart JC, Dawany N, Kelsen JR, de Zoeten EF, ... ... Kedl RM, et al. A novel human mutation results in T and NK cell-driven immune dysregulation. The Journal of Experimental Medicine. PMID 31040184 DOI: 10.1084/Jem.20182015 |
0.375 |
|
| 2019 |
Pritchard GH, Kedl RM, Hunter CA. The evolving role of T-bet in resistance to infection. Nature Reviews. Immunology. PMID 30846856 DOI: 10.1038/S41577-019-0145-4 |
0.497 |
|
| 2019 |
Cross EW, Blain TJ, Mathew D, Kedl RM. Anti-CD8 monoclonal antibody-mediated depletion alters the phenotype and behavior of surviving CD8+ T cells. Plos One. 14: e0211446. PMID 30735510 DOI: 10.1371/Journal.Pone.0211446 |
0.58 |
|
| 2019 |
Oberst A, Kedl R. Decision letter: Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway Elife. DOI: 10.7554/Elife.52687.Sa1 |
0.555 |
|
| 2018 |
Klarquist J, Chitrakar A, Pennock ND, Kilgore AM, Blain T, Zheng C, Danhorn T, Walton K, Jiang L, Sun J, Hunter CA, D'Alessandro A, Kedl RM. Clonal expansion of vaccine-elicited T cells is independent of aerobic glycolysis. Science Immunology. 3. PMID 30194241 DOI: 10.1126/Sciimmunol.Aas9822 |
0.442 |
|
| 2018 |
Atif SM, Gibbings SL, Redente EF, Camp FA, Torres RM, Kedl RM, Henson PM, Jakubzick CV. Immune Surveillance by Natural IgM is Required For Early Neoantigen Recognition and Initiation of Adaptive Immunity. American Journal of Respiratory Cell and Molecular Biology. PMID 29953261 DOI: 10.1165/Rcmb.2018-0159Oc |
0.596 |
|
| 2018 |
Vartuli RL, Zhou H, Zhang L, Powers RK, Klarquist J, Rudra P, Vincent MY, Ghosh D, Costello JC, Kedl RM, Slansky JE, Zhao R, Ford HL. Eya3 promotes breast tumor-associated immune suppression via threonine phosphatase-mediated PD-L1 upregulation. The Journal of Clinical Investigation. PMID 29757193 DOI: 10.1172/Jci96784 |
0.409 |
|
| 2018 |
Kedl RM, White JT. Foreign antigen-independent memory-phenotype CD4T cells: a new player in innate immunity? Nature Reviews. Immunology. 18: 1. PMID 29480288 DOI: 10.1038/Nri.2018.13 |
0.436 |
|
| 2018 |
Kilgore AM, Welsh S, Cheney EE, Chitrakar A, Blain TJ, Kedl BJ, Hunter CA, Pennock ND, Kedl RM. IL-27p28 Production by XCR1+ Dendritic Cells and Monocytes Effectively Predicts Adjuvant-Elicited CD8+ T Cell Responses. Immunohorizons. 2: 1-11. PMID 29354801 DOI: 10.4049/immunohorizons.1700054 |
0.463 |
|
| 2017 |
Kedl RM, Lindsay RS, Finlon JM, Lucas ED, Friedman RS, Tamburini BAJ. Migratory dendritic cells acquire and present lymphatic endothelial cell-archived antigens during lymph node contraction. Nature Communications. 8: 2034. PMID 29229919 DOI: 10.1038/S41467-017-02247-Z |
0.535 |
|
| 2017 |
Kedl RM, Seder R. Editorial overview: Vaccines. Current Opinion in Immunology. 47: A1-A2. PMID 28969845 DOI: 10.1016/J.Coi.2017.09.001 |
0.318 |
|
| 2017 |
White JT, Cross EW, Kedl RM. Antigen-inexperienced memory CD8(+) T cells: where they come from and why we need them. Nature Reviews. Immunology. PMID 28480897 DOI: 10.1038/Nri.2017.34 |
0.528 |
|
| 2017 |
Barrett BS, Harper MS, Jones ST, Guo K, Heilman KJ, Kedl RM, Hasenkrug KJ, Santiago ML. Type I interferon signaling is required for the APOBEC3/Rfv3-dependent neutralizing antibody response but not innate retrovirus restriction. Retrovirology. 14: 25. PMID 28415995 DOI: 10.1186/S12977-017-0349-2 |
0.315 |
|
| 2017 |
Nelsen MK, Beard KS, Plenter RJ, Kedl RM, Clambey ET, Gill RG. Disruption of Transplant Tolerance by an 'Incognito' Form of CD8(+) T Cell-Dependent Memory. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28066981 DOI: 10.1111/Ajt.14194 |
0.504 |
|
| 2016 |
Eberlein J, Davenport B, Nguyen T, Victorino F, Haist K, Jhun K, Karimpour-Fard A, Hunter L, Kedl R, Clambey ET, Homann D. Aging promotes acquisition of naive-like CD8+ memory T cell traits and enhanced functionalities. The Journal of Clinical Investigation. PMID 27617858 DOI: 10.1172/Jci88546 |
0.565 |
|
| 2016 |
White JT, Cross EW, Burchill MA, Danhorn T, McCarter MD, Rosen HR, O'Connor B, Kedl RM. Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner. Nature Communications. 7: 11291. PMID 27097762 DOI: 10.1038/Ncomms11291 |
0.584 |
|
| 2016 |
Pennock ND, Kedl JD, Kedl RM. T Cell Vaccinology: Beyond the Reflection of Infectious Responses. Trends in Immunology. 37: 170-80. PMID 26830540 DOI: 10.1016/J.It.2016.01.001 |
0.601 |
|
| 2015 |
Thompson EA, Liang F, Lindgren G, Sandgren KJ, Quinn KM, Darrah PA, Koup RA, Seder RA, Kedl RM, Loré K. Correction: Human Anti-CD40 Antibody and Poly IC:LC Adjuvant Combination Induces Potent T Cell Responses in the Lung of Nonhuman Primates. Journal of Immunology (Baltimore, Md. : 1950). 195: 3497-8. PMID 26386039 DOI: 10.4049/jimmunol.1501682 |
0.379 |
|
| 2015 |
Kedl RM, Tamburini BA. Antigen archiving by lymph node stroma: A novel function for the lymphatic endothelium. European Journal of Immunology. 45: 2721-9. PMID 26278423 DOI: 10.1002/Eji.201545739 |
0.531 |
|
| 2015 |
Burchill MA, Tamburini BA, Kedl RM. T cells compete by cleaving cell surface CD27 and blocking access to CD70-bearing APCs. European Journal of Immunology. 45: 3140-9. PMID 26179759 DOI: 10.1002/Eji.201545749 |
0.608 |
|
| 2015 |
Thompson EA, Liang F, Lindgren G, Sandgren KJ, Quinn KM, Darrah PA, Koup RA, Seder RA, Kedl RM, Loré K. Human Anti-CD40 Antibody and Poly IC:LC Adjuvant Combination Induces Potent T Cell Responses in the Lung of Nonhuman Primates. Journal of Immunology (Baltimore, Md. : 1950). 195: 1015-24. PMID 26123354 DOI: 10.4049/Jimmunol.1500078 |
0.637 |
|
| 2015 |
Kedl JD, Kedl RM. How squalene GLAdly helps generate antigen-specific T cells via antigen-carrying neutrophils and IL-18. European Journal of Immunology. 45: 376-9. PMID 25641415 DOI: 10.1002/Eji.201445379 |
0.472 |
|
| 2014 |
Zhang Y, Tian S, Liu Z, Zhang J, Zhang M, Bosenberg MW, Kedl RM, Waldmann TA, Storkus WJ, Falo LD, You Z. Dendritic cell-derived interleukin-15 is crucial for therapeutic cancer vaccine potency. Oncoimmunology. 3: e959321. PMID 25941586 DOI: 10.4161/21624011.2014.959321 |
0.561 |
|
| 2014 |
Pennock ND, Gapin L, Kedl RM. IL-27 is required for shaping the magnitude, affinity distribution, and memory of T cells responding to subunit immunization. Proceedings of the National Academy of Sciences of the United States of America. 111: 16472-7. PMID 25267651 DOI: 10.1073/Pnas.1407393111 |
0.589 |
|
| 2014 |
Desch AN, Gibbings SL, Clambey ET, Janssen WJ, Slansky JE, Kedl RM, Henson PM, Jakubzick C. Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction. Nature Communications. 5: 4674. PMID 25135627 DOI: 10.1038/Ncomms5674 |
0.587 |
|
| 2014 |
Christie M, Torres RM, Kedl RM, Randolph TW, Carpenter JF. Recombinant murine growth hormone particles are more immunogenic with intravenous than subcutaneous administration. Journal of Pharmaceutical Sciences. 103: 128-39. PMID 25133276 DOI: 10.1002/Jps.23794 |
0.317 |
|
| 2014 |
Tamburini BA, Burchill MA, Kedl RM. Antigen capture and archiving by lymphatic endothelial cells following vaccination or viral infection. Nature Communications. 5: 3989. PMID 24905362 DOI: 10.1038/Ncomms4989 |
0.498 |
|
| 2013 |
Pennock ND, White JT, Cross EW, Cheney EE, Tamburini BA, Kedl RM. T cell responses: naive to memory and everything in between. Advances in Physiology Education. 37: 273-83. PMID 24292902 DOI: 10.1152/Advan.00066.2013 |
0.544 |
|
| 2013 |
Sosinowski T, White JT, Cross EW, Haluszczak C, Marrack P, Gapin L, Kedl RM. CD8α+ dendritic cell trans presentation of IL-15 to naive CD8+ T cells produces antigen-inexperienced T cells in the periphery with memory phenotype and function. Journal of Immunology (Baltimore, Md. : 1950). 190: 1936-47. PMID 23355737 DOI: 10.4049/Jimmunol.1203149 |
0.589 |
|
| 2013 |
Lang J, Kelly M, Freed BM, McCarter MD, Kedl RM, Torres RM, Pelanda R. Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturation. Journal of Immunology (Baltimore, Md. : 1950). 190: 2090-101. PMID 23335750 DOI: 10.4049/Jimmunol.1202810 |
0.432 |
|
| 2013 |
Huang Y, Aydintug MK, Loomis J, Macleod MK, McKee AS, Kirchenbaum G, Jakubzick CV, Kedl RM, Sun D, Jacobelli J, O'Brien RL, Born WK. Antigen-specific regulation of IgE antibodies by non-antigen-specific γδ T cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 913-21. PMID 23275606 DOI: 10.4049/Jimmunol.1202230 |
0.467 |
|
| 2013 |
Burchill MA, Tamburini BA, Pennock ND, White JT, Kurche JS, Kedl RM. T cell vaccinology: exploring the known unknowns. Vaccine. 31: 297-305. PMID 23137843 DOI: 10.1016/J.Vaccine.2012.10.096 |
0.755 |
|
| 2013 |
Friend SF, Peterson LK, Kedl RM, Dragone LL. SLAP deficiency increases TCR avidity leading to altered repertoire and negative selection of cognate antigen-specific CD8+ T cells. Immunologic Research. 55: 116-24. PMID 22956467 DOI: 10.1007/S12026-012-8354-Y |
0.573 |
|
| 2013 |
Edwards LE, Haluszczak C, Kedl RM. Phenotype and function of protective, CD4-independent CD8 T cell memory. Immunologic Research. 55: 135-45. PMID 22948808 DOI: 10.1007/S12026-012-8356-9 |
0.823 |
|
| 2012 |
Nakagawa P, Liu Y, Liao TD, Chen X, González GE, Bobbitt KR, Smolarek D, Peterson EL, Kedl R, Yang XP, Rhaleb NE, Carretero OA. Treatment with N-acetyl-seryl-aspartyl-lysyl-proline prevents experimental autoimmune myocarditis in rats. American Journal of Physiology. Heart and Circulatory Physiology. 303: H1114-27. PMID 22923621 DOI: 10.1152/Ajpheart.00300.2011 |
0.455 |
|
| 2012 |
Sanchez PJ, Kedl RM. An alternative signal 3: CD8⁺ T cell memory independent of IL-12 and type I IFN is dependent on CD27/OX40 signaling. Vaccine. 30: 1154-61. PMID 22178730 DOI: 10.1016/J.Vaccine.2011.12.017 |
0.617 |
|
| 2012 |
Kurche JS, Haluszczak C, McWilliams JA, Sanchez PJ, Kedl RM. Type I IFN-dependent T cell activation is mediated by IFN-dependent dendritic cell OX40 ligand expression and is independent of T cell IFNR expression. Journal of Immunology (Baltimore, Md. : 1950). 188: 585-93. PMID 22156349 DOI: 10.4049/Jimmunol.1102550 |
0.802 |
|
| 2012 |
Tamburini BA, Kedl RM, Bellgrau D. IL-6-inducing whole yeast-based immunotherapy directly controls IL-12-dependent CD8 T-cell responses. Journal of Immunotherapy (Hagerstown, Md. : 1997). 35: 14-22. PMID 22130158 DOI: 10.1097/Cji.0B013E3182356888 |
0.605 |
|
| 2012 |
Huang Y, MacCLeod M, McKee A, Aydintug M, Jacubzick C, Kedl R, Sun D, O'Brien R, Born W. Interaction With Myd88-dependent CD8-CD11c+ Cells Mediates Rapid Induction Of Antigen-specific IgE-suppressive Gamma Delta T Cells Journal of Allergy and Clinical Immunology. 129: AB243. DOI: 10.1016/J.JACI.2011.12.044 |
0.535 |
|
| 2011 |
Kemmler CB, Clambey ET, Kedl RM, Slansky JE. Elevated tumor-associated antigen expression suppresses variant peptide vaccine responses. Journal of Immunology (Baltimore, Md. : 1950). 187: 4431-9. PMID 21940675 DOI: 10.4049/Jimmunol.1101555 |
0.496 |
|
| 2011 |
Desch AN, Randolph GJ, Murphy K, Gautier EL, Kedl RM, Lahoud MH, Caminschi I, Shortman K, Henson PM, Jakubzick CV. CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen. The Journal of Experimental Medicine. 208: 1789-97. PMID 21859845 DOI: 10.1084/Jem.20110538 |
0.616 |
|
| 2011 |
Oh JZ, Kurche JS, Burchill MA, Kedl RM. TLR7 enables cross-presentation by multiple dendritic cell subsets through a type I IFN-dependent pathway. Blood. 118: 3028-38. PMID 21813451 DOI: 10.1182/Blood-2011-04-348839 |
0.781 |
|
| 2011 |
Henderson A, Propst K, Kedl R, Dow S. Mucosal immunization with liposome-nucleic acid adjuvants generates effective humoral and cellular immunity. Vaccine. 29: 5304-12. PMID 21600950 DOI: 10.1016/J.Vaccine.2011.05.009 |
0.494 |
|
| 2010 |
Oh JZ, Kedl RM. The capacity to induce cross-presentation dictates the success of a TLR7 agonist-conjugate vaccine for eliciting cellular immunity. Journal of Immunology (Baltimore, Md. : 1950). 185: 4602-8. PMID 20844205 DOI: 10.4049/Jimmunol.1001892 |
0.819 |
|
| 2010 |
Kurche JS, Burchill MA, Sanchez PJ, Haluszczak C, Kedl RM. Comparison of OX40 ligand and CD70 in the promotion of CD4+ T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 185: 2106-15. PMID 20639485 DOI: 10.4049/Jimmunol.1000172 |
0.816 |
|
| 2010 |
McWilliams JA, Sanchez PJ, Haluszczak C, Gapin L, Kedl RM. Multiple innate signaling pathways cooperate with CD40 to induce potent, CD70-dependent cellular immunity. Vaccine. 28: 1468-76. PMID 19995538 DOI: 10.1016/J.Vaccine.2009.11.071 |
0.828 |
|
| 2009 |
Cubillos-Ruiz JR, Engle X, Scarlett UK, Martinez D, Barber A, Elgueta R, Wang L, Nesbeth Y, Durant Y, Gewirtz AT, Sentman CL, Kedl R, Conejo-Garcia JR. Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity. The Journal of Clinical Investigation. 119: 2231-44. PMID 19620771 DOI: 10.1172/Jci37716 |
0.452 |
|
| 2009 |
Takeda K, Dow SW, Miyahara N, Kodama T, Koya T, Taube C, Joetham A, Park JW, Dakhama A, Kedl RM, Gelfand EW. Vaccine-induced CD8+ T cell-dependent suppression of airway hyperresponsiveness and inflammation. Journal of Immunology (Baltimore, Md. : 1950). 183: 181-90. PMID 19542429 DOI: 10.4049/Jimmunol.0803967 |
0.621 |
|
| 2009 |
Haluszczak C, Akue AD, Hamilton SE, Johnson LD, Pujanauski L, Teodorovic L, Jameson SC, Kedl RM. The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion. The Journal of Experimental Medicine. 206: 435-48. PMID 19188498 DOI: 10.1084/Jem.20081829 |
0.602 |
|
| 2009 |
Zhang X, Kedl RM, Xiang J. CD40 ligation converts TGF-beta-secreting tolerogenic CD4-8- dendritic cells into IL-12-secreting immunogenic ones. Biochemical and Biophysical Research Communications. 379: 954-8. PMID 19135981 DOI: 10.1016/J.Bbrc.2008.12.179 |
0.586 |
|
| 2008 |
You Q, Cheng L, Kedl RM, Ju C. Mechanism of T cell tolerance induction by murine hepatic Kupffer cells. Hepatology (Baltimore, Md.). 48: 978-90. PMID 18712788 DOI: 10.1002/Hep.22395 |
0.59 |
|
| 2008 |
Ahonen CL, Wasiuk A, Fuse S, Turk MJ, Ernstoff MS, Suriawinata AA, Gorham JD, Kedl RM, Usherwood EJ, Noelle RJ. Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines. Blood. 111: 3116-25. PMID 18202224 DOI: 10.1182/Blood-2007-09-114371 |
0.602 |
|
| 2008 |
Jordan KR, McMahan RH, Oh JZ, Pipeling MR, Pardoll DM, Kedl RM, Kappler JW, Slansky JE. Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity. Journal of Immunology (Baltimore, Md. : 1950). 180: 188-97. PMID 18097019 DOI: 10.4049/Jimmunol.180.1.188 |
0.782 |
|
| 2008 |
Kedl RM, Teodorovic L, Haluszczak C, Jenkins M. The naïve CD8+ T cell pool contains a variable frequency of memory phenotype T cells bearing the signature of homeostatic expansion The Faseb Journal. 22: 355-355. DOI: 10.1096/Fasebj.22.2_Supplement.355 |
0.536 |
|
| 2007 |
Moon JJ, Chu HH, Pepper M, McSorley SJ, Jameson SC, Kedl RM, Jenkins MK. Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. Immunity. 27: 203-13. PMID 17707129 DOI: 10.1016/J.Immuni.2007.07.007 |
0.59 |
|
| 2007 |
Sanchez PJ, McWilliams JA, Haluszczak C, Yagita H, Kedl RM. Combined TLR/CD40 stimulation mediates potent cellular immunity by regulating dendritic cell expression of CD70 in vivo. Journal of Immunology (Baltimore, Md. : 1950). 178: 1564-72. PMID 17237405 DOI: 10.4049/Jimmunol.178.3.1564 |
0.824 |
|
| 2006 |
U'Ren L, Kedl R, Dow S. Vaccination with liposome--DNA complexes elicits enhanced antitumor immunity. Cancer Gene Therapy. 13: 1033-1044. PMID 16841080 DOI: 10.1038/Sj.Cgt.7700982 |
0.572 |
|
| 2006 |
McWilliams JA, McGurran SM, Dow SW, Slansky JE, Kedl RM. A modified tyrosinase-related protein 2 epitope generates high-affinity tumor-specific T cells but does not mediate therapeutic efficacy in an intradermal tumor model. Journal of Immunology (Baltimore, Md. : 1950). 177: 155-61. PMID 16785510 DOI: 10.4049/Jimmunol.177.1.155 |
0.792 |
|
| 2006 |
Zaks K, Jordan M, Guth A, Sellins K, Kedl R, Izzo A, Bosio C, Dow S. Efficient immunization and cross-priming by vaccine adjuvants containing TLR3 or TLR9 agonists complexed to cationic liposomes Journal of Immunology. 176: 7335-7345. PMID 16751377 DOI: 10.4049/Jimmunol.176.12.7335 |
0.609 |
|
| 2006 |
Wille-Reece U, Flynn BJ, Loré K, Koup RA, Miles AP, Saul A, Kedl RM, Mattapallil JJ, Weiss WR, Roederer M, Seder RA. Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates. The Journal of Experimental Medicine. 203: 1249-58. PMID 16636134 DOI: 10.1084/Jem.20052433 |
0.592 |
|
| 2005 |
Wille-Reece U, Flynn BJ, Loré K, Koup RA, Kedl RM, Mattapallil JJ, Weiss WR, Roederer M, Seder RA. HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates. Proceedings of the National Academy of Sciences of the United States of America. 102: 15190-4. PMID 16219698 DOI: 10.1073/Pnas.0507484102 |
0.527 |
|
| 2005 |
Wille-Reece U, Wu CY, Flynn BJ, Kedl RM, Seder RA. Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 174: 7676-83. PMID 15944268 DOI: 10.4049/Jimmunol.174.12.7676 |
0.619 |
|
| 2005 |
Gorden KB, Gorski KS, Gibson SJ, Kedl RM, Kieper WC, Qiu X, Tomai MA, Alkan SS, Vasilakos JP. Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8. Journal of Immunology (Baltimore, Md. : 1950). 174: 1259-68. PMID 15661881 DOI: 10.4049/Jimmunol.174.3.1259 |
0.396 |
|
| 2004 |
Ahonen CL, Doxsee CL, McGurran SM, Riter TR, Wade WF, Barth RJ, Vasilakos JP, Noelle RJ, Kedl RM. Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN. The Journal of Experimental Medicine. 199: 775-84. PMID 15007094 DOI: 10.1084/Jem.20031591 |
0.659 |
|
| 2003 |
Doxsee CL, Riter TR, Reiter MJ, Gibson SJ, Vasilakos JP, Kedl RM. The immune response modifier and Toll-like receptor 7 agonist S-27609 selectively induces IL-12 and TNF-alpha production in CD11c+CD11b+CD8- dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 1156-63. PMID 12874201 DOI: 10.4049/Jimmunol.171.3.1156 |
0.568 |
|
| 2003 |
Kedl RM, Kappler JW, Marrack P. Epitope dominance, competition and T cell affinity maturation. Current Opinion in Immunology. 15: 120-7. PMID 12495743 DOI: 10.1016/S0952-7915(02)00009-2 |
0.482 |
|
| 2002 |
Mitchell TC, Teague TK, Hildeman DA, Bender J, Rees WA, Kedl RM, Swanson B, Kappler JW, Marrack P. Stronger correlation of bcl-3 than bcl-2, bcl-xL, costimulation, or antioxidants with adjuvant-induced T cell survival. Annals of the New York Academy of Sciences. 975: 114-31. PMID 12538159 DOI: 10.1111/J.1749-6632.2002.Tb05946.X |
0.496 |
|
| 2002 |
Gibson SJ, Lindh JM, Riter TR, Gleason RM, Rogers LM, Fuller AE, Oesterich JL, Gorden KB, Qiu X, McKane SW, Noelle RJ, Miller RL, Kedl RM, Fitzgerald-Bocarsly P, Tomai MA, et al. Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod. Cellular Immunology. 218: 74-86. PMID 12470615 DOI: 10.1016/S0008-8749(02)00517-8 |
0.422 |
|
| 2002 |
Kedl RM, Schaefer BC, Kappler JW, Marrack P. T cells down-modulate peptide-MHC complexes on APCs in vivo. Nature Immunology. 3: 27-32. PMID 11731800 DOI: 10.1038/Ni742 |
0.509 |
|
| 2001 |
Schaefer BC, Schaefer ML, Kappler JW, Marrack P, Kedl RM. Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo. Cellular Immunology. 214: 110-22. PMID 12088410 DOI: 10.1006/Cimm.2001.1895 |
0.507 |
|
| 2001 |
Kedl RM, Jordan M, Potter T, Kappler J, Marrack P, Dow S. CD40 stimulation accelerates deletion of tumor-specific CD8(+) T cells in the absence of tumor-antigen vaccination. Proceedings of the National Academy of Sciences of the United States of America. 98: 10811-6. PMID 11526222 DOI: 10.1073/Pnas.191371898 |
0.603 |
|
| 2001 |
Mitchell TC, Hildeman D, Kedl RM, Teague TK, Schaefer BC, White J, Zhu Y, Kappler J, Marrack P. Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nature Immunology. 2: 397-402. PMID 11323692 DOI: 10.1038/87692 |
0.473 |
|
| 2000 |
Kedl RM, Rees WA, Hildeman DA, Schaefer B, Mitchell T, Kappler J, Marrack P. T cells compete for access to antigen-bearing antigen-presenting cells. The Journal of Experimental Medicine. 192: 1105-13. PMID 11034600 DOI: 10.1084/Jem.192.8.1105 |
0.587 |
|
| 2000 |
Marrack P, Mitchell T, Hildeman D, Kedl R, Teague TK, Bender J, Rees W, Schaefer BC, Kappler J. Genomic-scale analysis of gene expression in resting and activated T cells. Current Opinion in Immunology. 12: 206-9. PMID 10712937 DOI: 10.1016/S0952-7915(99)00075-8 |
0.365 |
|
| 1999 |
Teague TK, Hildeman D, Kedl RM, Mitchell T, Rees W, Schaefer BC, Bender J, Kappler J, Marrack P. Activation changes the spectrum but not the diversity of genes expressed by T cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 12691-6. PMID 10535984 DOI: 10.1073/Pnas.96.22.12691 |
0.429 |
|
| 1999 |
Rees W, Bender J, Teague TK, Kedl RM, Crawford F, Marrack P, Kappler J. An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proceedings of the National Academy of Sciences of the United States of America. 96: 9781-6. PMID 10449771 DOI: 10.1073/Pnas.96.17.9781 |
0.527 |
|
| 1998 |
Marrack P, Mitchell T, Bender J, Hildeman D, Kedl R, Teague K, Kappler J. T-cell survival. Immunological Reviews. 165: 279-85. PMID 9850867 DOI: 10.1111/J.1600-065X.1998.Tb01245.X |
0.473 |
|
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