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James O. McNamara - Publications

Affiliations: 
Duke University, Durham, NC 
Area:
epilepsy
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142 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Krishnamurthy K, Huang YZ, Harward SC, Sharma KK, Tamayo DL, McNamara JO. Regression of epileptogenesis by inhibiting TrkB signaling following a seizure. Annals of Neurology. PMID 31525273 DOI: 10.1002/ana.25602  0.6
2019 Lin TW, Harward SC, Huang YZ, McNamara JO. Targeting BDNF/TrkB Pathways for Preventing or Suppressing Epilepsy. Neuropharmacology. 107734. PMID 31377199 DOI: 10.1016/j.neuropharm.2019.107734  0.6
2019 Zhong Huang Y, He XP, Krishnamurthy K, McNamara JO. TrkB-Shc signaling protects against hippocampal injury following status epilepticus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30926745 DOI: 10.1523/JNEUROSCI.2939-18.2019  0.48
2018 Anderson RJ, Cook JJ, Delpratt N, Nouls JC, Gu B, McNamara JO, Avants BB, Johnson GA, Badea A. Small Animal Multivariate Brain Analysis (SAMBA) - a High Throughput Pipeline with a Validation Framework. Neuroinformatics. PMID 30565026 DOI: 10.1007/s12021-018-9410-0  0.4
2018 Pan E, Zhao Z, McNamara JO. LTD at mossy fiber synapses onto stratum lucidum interneurons requires TrkB and retrograde endocannabinoid signaling. Journal of Neurophysiology. PMID 30517040 DOI: 10.1152/jn.00669.2018  0.56
2017 Dingledine R, Coulter DA, Fritsch B, Gorter JA, Lelutiu N, McNamara J, Nadler JV, Pitkänen A, Rogawski MA, Skene P, Sloviter RS, Wang Y, Wadman WJ, Wasterlain C, Roopra A. Transcriptional profile of hippocampal dentate granule cells in four rat epilepsy models. Scientific Data. 4: 170061. PMID 28485718 DOI: 10.1038/sdata.2017.61  1
2016 Alexander GM, Huang YZ, Soderblom EJ, He XP, Moseley AM, McNamara JO. Vagal Nerve Stimulation Modifies Neuronal Activity and the Proteome of Excitatory Synapses of Amygdala/Piriform Cortex. Journal of Neurochemistry. PMID 27973753 DOI: 10.1111/jnc.13931  0.6
2016 Rigbye KA, van Hasselt PM, Burgess R, Damiano JA, Mullen SA, Petrovski S, Puranam RS, van Gassen KL, Gecz J, Scheffer IE, McNamara JO, Berkovic SF, Hildebrand MS. Is FGF13 a major contributor to genetic epilepsy with febrile seizures plus? Epilepsy Research. 128: 48-51. PMID 27810516 DOI: 10.1016/j.eplepsyres.2016.10.008  0.52
2016 Harward SC, Hedrick NG, Hall CE, Parra-Bueno P, Milner TA, Pan E, Laviv T, Hempstead BL, Yasuda R, McNamara JO. Autocrine BDNF-TrkB signalling within a single dendritic spine. Nature. PMID 27680698 DOI: 10.1038/nature19766  0.56
2015 Gu B, Huang YZ, He XP, Joshi RB, Jang W, McNamara JO. A Peptide Uncoupling BDNF Receptor TrkB from Phospholipase Cγ1 Prevents Epilepsy Induced by Status Epilepticus. Neuron. PMID 26481038 DOI: 10.1016/j.neuron.2015.09.032  0.6
2015 Puranam RS, He XP, Yao L, Le T, Jang W, Rehder CW, Lewis DV, McNamara JO. Disruption of Fgf13 Causes Synaptic Excitatory-Inhibitory Imbalance and Genetic Epilepsy and Febrile Seizures Plus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8866-81. PMID 26063919 DOI: 10.1523/JNEUROSCI.3470-14.2015  0.52
2014 Helgager J, Huang YZ, Mcnamara JO. Brain-derived neurotrophic factor but not vesicular zinc promotes TrkB activation within mossy fibers of mouse hippocampus in vivo. The Journal of Comparative Neurology. 522: 3885-99. PMID 25043764 DOI: 10.1002/cne.23647  0.6
2014 Liu G, Kotloski RJ, McNamara JO. Antiseizure effects of TrkB kinase inhibition. Epilepsia. 55: 1264-73. PMID 24903749 DOI: 10.1111/epi.12671  0.56
2014 He XP, Wen R, McNamara JO. Impairment of kindling development in phospholipase Cγ1 heterozygous mice. Epilepsia. 55: 456-63. PMID 24502564 DOI: 10.1111/epi.12536  0.48
2013 Ruzzo EK, Capo-Chichi JM, Ben-Zeev B, Chitayat D, Mao H, Pappas AL, Hitomi Y, Lu YF, Yao X, Hamdan FF, Pelak K, Reznik-Wolf H, Bar-Joseph I, Oz-Levi D, Lev D, ... ... McNamara JO, et al. Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy. Neuron. 80: 429-41. PMID 24139043 DOI: 10.1016/j.neuron.2013.08.013  0.48
2013 Liu G, Gu B, He XP, Joshi RB, Wackerle HD, Rodriguiz RM, Wetsel WC, McNamara JO. Transient inhibition of TrkB kinase after status epilepticus prevents development of temporal lobe epilepsy. Neuron. 79: 31-8. PMID 23790754 DOI: 10.1016/j.neuron.2013.04.027  0.56
2013 Wang HG, He XP, Li Q, Madison RD, Moore SD, McNamara JO, Pitt GS. The auxiliary subunit KChIP2 is an essential regulator of homeostatic excitability. The Journal of Biological Chemistry. 288: 13258-68. PMID 23536187 DOI: 10.1074/jbc.M112.434548  0.48
2013 Helgager J, Liu G, McNamara JO. The cellular and synaptic location of activated TrkB in mouse hippocampus during limbic epileptogenesis. The Journal of Comparative Neurology. 521: 499-521, Spc1. PMID 22987780 DOI: 10.1002/cne.23225  0.6
2012 Huang YZ, McNamara JO. Neuroprotective effects of reactive oxygen species mediated by BDNF-independent activation of TrkB. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15521-32. PMID 23115189 DOI: 10.1523/JNEUROSCI.0755-12.2012  0.6
2012 Soren Leonard A, Puranam RS, Helgager J, Liu G, McNamara JO. Conditional deletion of TrkC does not modify limbic epileptogenesis. Epilepsy Research. 102: 126-30. PMID 22980123 DOI: 10.1016/j.eplepsyres.2012.07.019  0.6
2012 Heinzen EL, Depondt C, Cavalleri GL, Ruzzo EK, Walley NM, Need AC, Ge D, He M, Cirulli ET, Zhao Q, Cronin KD, Gumbs CE, Campbell CR, Hong LK, Maia JM, ... ... McNamara JO, et al. Exome sequencing followed by large-scale genotyping fails to identify single rare variants of large effect in idiopathic generalized epilepsy. American Journal of Human Genetics. 91: 293-302. PMID 22863189 DOI: 10.1016/j.ajhg.2012.06.016  0.52
2012 Huang YZ, Hernandez FJ, Gu B, Stockdale KR, Nanapaneni K, Scheetz TE, Behlke MA, Peek AS, Bair T, Giangrande PH, McNamara JO. RNA aptamer-based functional ligands of the neurotrophin receptor, TrkB. Molecular Pharmacology. 82: 623-35. PMID 22752556 DOI: 10.1124/mol.112.078220  0.6
2012 Jones DL, McNamara JO. The Epilepsies: Phenotypes and Mechanisms Basic Neurochemistry. 705-718. DOI: 10.1016/B978-0-12-374947-5.00040-7  0.92
2011 Pan E, Zhang XA, Huang Z, Krezel A, Zhao M, Tinberg CE, Lippard SJ, McNamara JO. Vesicular zinc promotes presynaptic and inhibits postsynaptic long-term potentiation of mossy fiber-CA3 synapse. Neuron. 71: 1116-26. PMID 21943607 DOI: 10.1016/j.neuron.2011.07.019  0.56
2010 He XP, Pan E, Sciarretta C, Minichiello L, McNamara JO. Disruption of TrkB-mediated phospholipase Cgamma signaling inhibits limbic epileptogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6188-96. PMID 20445044 DOI: 10.1523/JNEUROSCI.5821-09.2010  0.56
2010 Huang YZ, McNamara JO. Mutual regulation of Src family kinases and the neurotrophin receptor TrkB. The Journal of Biological Chemistry. 285: 8207-17. PMID 20064930 DOI: 10.1074/jbc.M109.091041  0.6
2010 Kotloski R, McNamara JO. Reduction of TrkB expression de novo in the adult mouse impairs epileptogenesis in the kindling model. Hippocampus. 20: 713-23. PMID 19603519 DOI: 10.1002/hipo.20673  0.56
2008 Tahirovic YA, Geballe M, Gruszecka-Kowalik E, Myers SJ, Lyuboslavsky P, Le P, French A, Irier H, Choi WB, Easterling K, Yuan H, Wilson LJ, Kotloski R, McNamara JO, Dingledine R, et al. Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists. Journal of Medicinal Chemistry. 51: 5506-21. PMID 18800760 DOI: 10.1021/jm8002153  1
2008 Huang YZ, Pan E, Xiong ZQ, McNamara JO. Zinc-mediated transactivation of TrkB potentiates the hippocampal mossy fiber-CA3 pyramid synapse. Neuron. 57: 546-58. PMID 18304484 DOI: 10.1016/j.neuron.2007.11.026  0.96
2008 McNamara JO, Huang YZ, Pan E. Plasticity of dentate granule cell mossy fiber synapses: A Putative mechanism of limbic epileptogenesis Structural and Functional Organization of the Synapse. 715-729. DOI: 10.1007/978-0-387-77232-5_24  0.6
2006 Huang YZ, McNamara JO. Inhibiting glycolysis to reduce seizures: how it might work. Nature Neuroscience. 9: 1351-2. PMID 17066061 DOI: 10.1038/nn1106-1351  0.6
2006 McNamara JO, Huang YZ, Leonard AS. Molecular signaling mechanisms underlying epileptogenesis. Science's Stke : Signal Transduction Knowledge Environment. 2006: re12. PMID 17033045 DOI: 10.1126/stke.3562006re12  0.6
2006 He XP, Butler L, Liu X, McNamara JO. The tyrosine receptor kinase B ligand, neurotrophin-4, is not required for either epileptogenesis or tyrosine receptor kinase B activation in the kindling model. Neuroscience. 141: 515-20. PMID 16650613 DOI: 10.1016/j.neuroscience.2006.03.020  0.68
2005 Puranam RS, Jain S, Kleindienst AM, Saxena S, Kim MK, Kelly Changizi B, Padma MV, Andrews I, Elston RC, Tiwari HK, McNamara JO. A locus for generalized tonic-clonic seizure susceptibility maps to chromosome 10q25-q26. Annals of Neurology. 58: 449-58. PMID 16130088 DOI: 10.1002/ana.20598  0.52
2004 Huang Y, McNamara JO. Ischemic stroke: "acidotoxicity" is a perpetrator. Cell. 118: 665-6. PMID 15369664 DOI: 10.1016/j.cell.2004.09.004  0.96
2004 He XP, Kotloski R, Nef S, Luikart BW, Parada LF, McNamara JO. Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model. Neuron. 43: 31-42. PMID 15233915 DOI: 10.1016/j.neuron.2004.06.019  0.56
2004 Danzer SC, Pan E, Nef S, Parada LF, McNamara JO. Altered regulation of brain-derived neurotrophic factor protein in hippocampus following slice preparation. Neuroscience. 126: 859-69. PMID 15207321 DOI: 10.1016/j.neuroscience.2004.03.025  0.56
2003 Barnes G, Puranam RS, Luo Y, McNamara JO. Temporal specific patterns of semaphorin gene expression in rat brain after kainic acid-induced status epilepticus. Hippocampus. 13: 1-20. PMID 12625453 DOI: 10.1002/hipo.10041  0.52
2003 Xiong ZQ, Qian W, Suzuki K, McNamara JO. Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 955-60. PMID 12574424  0.96
2002 Xiong ZQ, McNamara JO. Fleeting activation of ionotropic glutamate receptors sensitizes cortical neurons to complement attack. Neuron. 36: 363-74. PMID 12408841 DOI: 10.1016/S0896-6273(02)00977-7  0.96
2002 Xiong ZQ, McNamara JO. Fas(t) balls and Lou Gehrig disease. A clue to selective vulnerability of motor neurons? Neuron. 35: 1011-3. PMID 12354390 DOI: 10.1016/S0896-6273(02)00910-8  0.96
2002 He XP, Minichiello L, Klein R, McNamara JO. Immunohistochemical evidence of seizure-induced activation of trkB receptors in the mossy fiber pathway of adult mouse hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7502-8. PMID 12196573  0.48
2001 Andrews PI, Dichter MA, Berkovic SF, Newton MR, McNamara JO. Plasmapheresis in Rasmussen's encephalitis. 1996. Neurology. 57: S37-41. PMID 11775607  0.48
2001 Puranam RS, McNamara JO. Epilepsy and all that jazz. Nature Medicine. 7: 1103-5. PMID 11590427 DOI: 10.1038/nm1001-1103  0.52
2000 Yang R, Puranam RS, Butler LS, Qian WH, He XP, Moyer MB, Blackburn K, Andrews PI, McNamara JO. Autoimmunity to munc-18 in Rasmussen's encephalitis. Neuron. 28: 375-83. PMID 11144349  0.52
2000 Whitney KD, McNamara JO. GluR3 autoantibodies destroy neural cells in a complement-dependent manner modulated by complement regulatory proteins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7307-16. PMID 11007888  0.48
1999 McNamara JO, Whitney KD, Andrews PI, He XP, Janumpalli S, Patel MN. Evidence for glutamate receptor autoimmunity in the pathogenesis of Rasmussen encephalitis. Advances in Neurology. 79: 543-50. PMID 10514842  1
1999 Whitney KD, Andrews PI, McNamara JO. Immunoglobulin G and complement immunoreactivity in the cerebral cortex of patients with Rasmussen's encephalitis. Neurology. 53: 699-708. PMID 10489029  0.48
1999 Puranam RS, McNamara JO. Seizure disorders in mutant mice: relevance to human epilepsies. Current Opinion in Neurobiology. 9: 281-7. PMID 10395577 DOI: 10.1016/S0959-4388(99)80041-5  0.52
1999 Whitney KD, McNamara JO. Autoimmunity and neurological disease: antibody modulation of synaptic transmission. Annual Review of Neuroscience. 22: 175-95. PMID 10202536 DOI: 10.1146/annurev.neuro.22.1.175  0.48
1998 Wilson MH, Puranam RS, Ottman R, Gilliam C, Limbird LE, George AL, McNamara JO. Evaluation of the alpha(2A)-adrenergic receptor gene in a heritable form of temporal lobe epilepsy. Neurology. 51: 1730-1. PMID 9855534 DOI: 10.1212/WNL.51.6.1730  0.52
1998 Puranam RS, McNamara JO. Stargazing nets new calcium channel subunit. Nature Genetics. 19: 313-4. PMID 9697685 DOI: 10.1038/1194  0.52
1998 Parent JM, Janumpalli S, McNamara JO, Lowenstein DH. Increased dentate granule cell neurogenesis following amygdala kindling in the adult rat. Neuroscience Letters. 247: 9-12. PMID 9637397 DOI: 10.1016/S0304-3940(98)00269-9  0.48
1998 McNamara JO, Puranam RS. Epilepsy genetics: an abundance of riches for biologists. Current Biology : Cb. 8: R168-70. PMID 9501059  0.52
1998 Janumpalli S, Butler LS, MacMillan LB, Limbird LE, McNamara JO. A point mutation (D79N) of the alpha2A adrenergic receptor abolishes the antiepileptogenic action of endogenous norepinephrine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2004-8. PMID 9482787  0.48
1998 He XP, Patel M, Whitney KD, Janumpalli S, Tenner A, McNamara JO. Glutamate receptor GluR3 antibodies and death of cortical cells. Neuron. 20: 153-63. PMID 9459451 DOI: 10.1016/S0896-6273(00)80443-2  0.48
1996 McNamara JO, Patel M, He XP, Janumpalli S, Whitney KD. Glutamate receptor autoimmunity in Rasmussen's encephalitis. Cold Spring Harbor Symposia On Quantitative Biology. 61: 327-32. PMID 9246462  0.48
1996 Patel M, Day BJ, Crapo JD, Fridovich I, McNamara JO. Requirement for superoxide in excitotoxic cell death. Neuron. 16: 345-55. PMID 8789949 DOI: 10.1016/S0896-6273(00)80052-5  0.36
1996 Andrews PI, McNamara JO. Rasmussen's encephalitis: an autoimmune disorder? Current Opinion in Neurology. 9: 141-5. PMID 8782983  0.48
1996 McNamara JO, Puranam RS. Epilepsy. Protease inhibitor implicated. Nature. 381: 26-7. PMID 8609982 DOI: 10.1038/381026a0  0.52
1996 Andrews PI, Dichter MA, Berkovic SF, Newton MR, McNamara JO. Plasmapheresis in Rasmussen's encephalitis. Neurology. 46: 242-6. PMID 8559385  0.48
1996 Jain S, Dixit SN, Andrews PI, Radtke R, Maheshwari MC, McNamara JO. Disease expression among probands with juvenile myoclonic epilepsy and their family members in two population groups Journal of Epilepsy. 9: 259-267. DOI: 10.1016/S0896-6974(96)00040-0  0.48
1995 Patel MN, McNamara JO. Selective enhancement of axonal branching of cultured dentate gyrus neurons by neurotrophic factors. Neuroscience. 69: 763-70. PMID 8596646 DOI: 10.1016/0306-4522(95)00281-M  1
1995 Hosford DA, Simonato M, Cao Z, Garcia-Cairasco N, Silver JM, Butler L, Shin C, McNamara JO. Differences in the anatomic distribution of immediate-early gene expression in amygdala and angular bundle kindling development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 2513-23. PMID 7891185  0.68
1994 Shin C, McNamara JO. Mechanism of epilepsy. Annual Review of Medicine. 45: 379-89. PMID 8198389 DOI: 10.1146/annurev.med.45.1.379  0.4
1994 Rogers SW, Andrews PI, Gahring LC, Whisenand T, Cauley K, Crain B, Hughes TE, Heinemann SF, McNamara JO. Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis. Science (New York, N.Y.). 265: 648-51. PMID 8036512  0.48
1994 Kraus JE, Yeh GC, Bonhaus DW, Nadler JV, McNamara JO. Kindling induces the long-lasting expression of a novel population of NMDA receptors in hippocampal region CA3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 4196-205. PMID 8027771  0.4
1993 Eubanks JH, Puranam RS, Kleckner NW, Bettler B, Heinemann SF, McNamara JO. The gene encoding the glutamate receptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 90: 178-82. PMID 8419920  0.52
1993 McNamara JO, Fridovich I. Human genetics. Did radicals strike Lou Gehrig? Nature. 362: 20-1. PMID 8383294 DOI: 10.1038/362020a0  0.36
1993 Labiner DM, Butler LS, Cao Z, Hosford DA, Shin C, McNamara JO. Induction of c-fos mRNA by kindled seizures: complex relationship with neuronal burst firing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 744-51. PMID 8381172  0.4
1993 Shafqat S, Tamarappoo BK, Kilberg MS, Puranam RS, McNamara JO, Guadaño-Ferraz A, Fremeau RT. Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters. The Journal of Biological Chemistry. 268: 15351-5. PMID 8340364  0.52
1993 Puranam RS, Eubanks JH, Heinemann SF, McNamara JO. Chromosomal localization of gene for human glutamate receptor subunit-7. Somatic Cell and Molecular Genetics. 19: 581-8. PMID 8128318 DOI: 10.1007/BF01233385  0.52
1992 Bonhaus DW, McNamara JO. Uncompetitive antagonist binding: a biochemical index of activation of the NMDA receptor-coupled ion channel. Epilepsy Research. Supplement. 8: 181-8. PMID 1384539  0.4
1992 McNamara JO, Eubanks JH, McPherson JD, Wasmuth JJ, Evans GA, Heinemann SF. Chromosomal localization of human glutamate receptor genes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 2555-62. PMID 1319477  0.4
1991 Silver JM, Shin C, McNamara JO. Antiepileptogenic effects of conventional anticonvulsants in the kindling model of epilespy. Annals of Neurology. 29: 356-63. PMID 1929206 DOI: 10.1002/ana.410290404  0.4
1991 Bonhaus DW, Russell RD, McNamara JO. Activation of substantia nigra pars reticulata neurons: role in the initiation and behavioral expression of kindled seizures. Brain Research. 545: 41-8. PMID 1860059 DOI: 10.1016/0006-8993(91)91267-5  0.4
1991 Hosford DA, Crain BJ, Cao Z, Bonhaus DW, Friedman AH, Okazaki MM, Nadler JV, McNamara JO. Increased AMPA-sensitive quisqualate receptor binding and reduced NMDA receptor binding in epileptic human hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 428-34. PMID 1846907  0.4
1991 Simonato M, Hosford DA, Labiner DM, Shin C, Mansbach HH, McNamara JO. Differential expression of immediate early genes in the hippocampus in the kindling model of epilepsy. Brain Research. Molecular Brain Research. 11: 115-24. PMID 1661808 DOI: 10.1016/0169-328X(91)90113-C  0.4
1990 Bonhaus DW, Perry WB, McNamara JO. Decreased density, but not number, of N-methyl-D-aspartate, glycine and phencyclidine binding sites in hippocampus of senescent rats. Brain Research. 532: 82-6. PMID 2178039 DOI: 10.1016/0006-8993(90)91745-3  0.4
1990 Dingledine R, McBain CJ, McNamara JO. Excitatory amino acid receptors in epilepsy. Trends in Pharmacological Sciences. 11: 334-8. PMID 2168104 DOI: 10.1016/0165-6147(90)90238-4  1
1990 McNamara JO, Yeh G, Bonhaus DW, Okazaki M, Nadler JV. NMDA receptor plasticity in the kindling model. Advances in Experimental Medicine and Biology. 268: 451-9. PMID 2150158  0.4
1990 Shin C, McNamara JO, Morgan JI, Curran T, Cohen DR. Induction of c-fos mRNA expression by afterdischarge in the hippocampus of naive and kindled rats. Journal of Neurochemistry. 55: 1050-5. PMID 2117045  0.4
1990 Yeh GC, Bonhaus DW, McNamara JO. Evidence that zinc inhibits N-methyl-D-aspartate receptor-gated ion channel activation by noncompetitive antagonism of glycine binding. Molecular Pharmacology. 38: 14-9. PMID 1695316  0.4
1990 Hosford DA, Bonhaus DW, McNamara JO. A radiohistochemical measure of [3H]TCP binding to the activated NMDA-receptor-gated ion channel in rat brain. Brain Research. 516: 192-200. PMID 1694710 DOI: 10.1016/0006-8993(90)90918-2  0.4
1990 Morrisett RA, Chow CC, Sakaguchi T, Shin C, McNamara JO. Inhibition of muscarinic-coupled phosphoinositide hydrolysis by N-methyl-D-aspartate is dependent on depolarization via channel activation. Journal of Neurochemistry. 54: 1517-25. PMID 1691275  0.4
1989 McNamara JO, Rigsbee LC, Butler LS, Shin C. Intravenous phenytoin is an effective anticonvulsant in the kindling model. Annals of Neurology. 26: 675-8. PMID 2817842 DOI: 10.1002/ana.410260514  0.4
1989 Traynelis SF, Dingledine R, McNamara JO, Butler L, Rigsbee L. Effect of kindling on potassium-induced electrographic seizures in vitro. Neuroscience Letters. 105: 326-32. PMID 2594218 DOI: 10.1016/0304-3940(89)90642-3  1
1989 Bonhaus DW, McNamara JO. TCP binding: a tool for studying NMDA receptor-mediated neurotransmission in kindling. Neuroscience and Biobehavioral Reviews. 13: 261-7. PMID 2558331 DOI: 10.1016/S0149-7634(89)80060-0  0.4
1989 Yeh GC, Bonhaus DW, Nadler JV, McNamara JO. N-methyl-D-aspartate receptor plasticity in kindling: quantitative and qualitative alterations in the N-methyl-D-aspartate receptor-channel complex. Proceedings of the National Academy of Sciences of the United States of America. 86: 8157-60. PMID 2479019  0.4
1989 Bonhaus DW, Yeh GC, Skaryak L, McNamara JO. Glycine regulation of the N-methyl-D-aspartate receptor-gated ion channel in hippocampal membranes. Molecular Pharmacology. 36: 273-9. PMID 2475759  0.4
1989 McNamara JO, Bonhaus DW, Nadler JV. Novel approach to studying N-methyl-D-aspartate receptor function in the kindling model of epilepsy Drug Development Research. 17: 321-330.  0.4
1988 McNamara JO, Russell RD, Rigsbee L, Bonhaus DW. Anticonvulsant and antiepileptogenic actions of MK-801 in the kindling and electroshock models. Neuropharmacology. 27: 563-8. PMID 2843782 DOI: 10.1016/0028-3908(88)90176-1  0.68
1988 Bonhaus DW, McNamara JO. N-methyl-D-aspartate receptor regulation of uncompetitive antagonist binding in rat brain membranes: kinetic analysis. Molecular Pharmacology. 34: 250-5. PMID 2843744  0.4
1988 Bonhaus DW, McNamara JO. Anticonvulsant action of intranigral gamma-vinyl-GABA: role of nonadrenergic neurotransmission. Brain Research. 438: 391-4. PMID 2830944 DOI: 10.1016/0006-8993(88)91370-4  0.4
1988 Hosford DA, Bonhaus DW, McNamara JO. Radiohistochemical demonstration of NMDA/glycine-channel activation in rat hippocampus. European Journal of Pharmacology. 151: 501-3. PMID 2463927 DOI: 10.1016/0014-2999(88)90552-3  0.4
1987 Bonhaus DW, McNamara JO. Activity of locus coeruleus neurons in amygdala kindled rats: role in the suppression of afterdischarge. Brain Research. 407: 102-9. PMID 3580845 DOI: 10.1016/0006-8993(87)91223-6  0.4
1987 King PH, Shin C, Mansbach HH, Chen LS, McNamara JO. Microinjection of a benzodiazepine into substantia nigra elevates kindled seizure threshold. Brain Research. 423: 261-8. PMID 3315121 DOI: 10.1016/0006-8993(87)90848-1  0.4
1987 Shin C, Silver JM, Bonhaus DW, McNamara JO. The role of substantia nigra in the development of kindling: pharmacologic and lesion studies. Brain Research. 412: 311-7. PMID 3300851 DOI: 10.1016/0006-8993(87)91138-3  0.4
1987 Shin C, Scialabba FA, McNamara JO. Stimulation of substantia nigra pars reticulata enhances dentate granule cell excitability. Brain Research. 411: 21-7. PMID 3300844 DOI: 10.1016/0006-8993(87)90677-9  0.4
1987 Crain BJ, Chang KJ, McNamara JO. An in vitro autoradiographic analysis of mu and delta opioid binding in the hippocampal formation of kindled rats. Brain Research. 412: 343-51. PMID 3038268 DOI: 10.1016/0006-8993(87)91141-3  0.4
1987 Platt K, Butler LS, Bonhaus DW, McNamara JO. Evidence implicating alpha-2 adrenergic receptors in the anticonvulsant action of intranigral muscimol. The Journal of Pharmacology and Experimental Therapeutics. 241: 751-4. PMID 3037068  0.4
1987 Gellman RL, Kallianos JA, McNamara JO. Alpha-2 receptors mediate an endogenous noradrenergic suppression of kindling development. The Journal of Pharmacology and Experimental Therapeutics. 241: 891-8. PMID 2885413  0.4
1987 Bonhaus DW, Rigsbee LC, McNamara JO. Intranigral dynorphin-1-13 suppresses kindled seizures by a naloxone-insensitive mechanism. Brain Research. 405: 358-63. PMID 2882815 DOI: 10.1016/0006-8993(87)90306-4  0.4
1987 Bonhaus DW, Burge BC, McNamara JO. Biochemical evidence that glycine allosterically regulates an NMDA receptor-coupled ion channel. European Journal of Pharmacology. 142: 489-90. PMID 2448149 DOI: 10.1016/0014-2999(87)90096-3  0.4
1986 Frush DP, Giacchino JL, McNamara JO. Evidence implicating dentate granule cells in development of entorhinal kindling. Experimental Neurology. 92: 92-101. PMID 3956661 DOI: 10.1016/0014-4886(86)90127-5  0.6
1986 Frush DP, McNamara JO. Evidence implicating dentate granule cells in wet dog shakes produced by kindling stimulations of entorhinal cortex. Experimental Neurology. 92: 102-13. PMID 3956642 DOI: 10.1016/0014-4886(86)90128-7  0.44
1986 Bonhaus DW, Walters JR, McNamara JO. Activation of substantia nigra neurons: role in the propagation of seizures in kindled rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 3024-30. PMID 3760946  0.4
1986 McNamara JO, Bonhaus DW, Shin C. Role of the substantia nigra in the kindling model of limbic epilepsy. Advances in Experimental Medicine and Biology. 203: 139-46. PMID 3538808  0.4
1986 Silver JM, Bonhaus DW, McNamara JO. Method of lesioning brainstem determines seizure probability. Journal of Neuroscience Methods. 17: 303-10. PMID 3537541 DOI: 10.1016/0165-0270(86)90131-7  0.4
1986 Somjen GG, Aitken PG, Giacchino JL, McNamara JO. Interstitial ion concentrations and paroxysmal discharges in hippocampal formation and spinal cord. Advances in Neurology. 44: 663-80. PMID 3518351  0.6
1986 Shin C, Rigsbee LC, McNamara JO. Anti-seizure and anti-epileptogenic effect of gamma-vinyl gamma-aminobutyric acid in amygdaloid kindling. Brain Research. 398: 370-4. PMID 3026570 DOI: 10.1016/0006-8993(86)91498-8  0.4
1986 Crain BJ, Chang KJ, McNamara JO. Quantitative autoradiographic analysis of mu and delta opioid binding sites in the rat hippocampal formation. The Journal of Comparative Neurology. 246: 170-80. PMID 3007584 DOI: 10.1002/cne.902460203  0.4
1986 Fanelli RJ, McNamara JO. Effects of age on kindling and kindled seizure-induced increase of benzodiazepine receptor binding. Brain Research. 362: 17-22. PMID 3002549 DOI: 10.1016/0006-8993(86)91393-4  0.64
1986 Iadarola MJ, Shin C, McNamara JO, Yang HY. Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling. Brain Research. 365: 185-91. PMID 2868784 DOI: 10.1016/0006-8993(86)90738-9  0.4
1985 Somjen GG, Aitken PG, Giacchino JL, McNamara JO. Sustained potential shifts and paroxysmal discharges in hippocampal formation. Journal of Neurophysiology. 53: 1079-97. PMID 3998793  0.6
1985 Savage DD, Rigsbee LC, McNamara JO. Knife cuts of entorhinal cortex: effects on development of amygdaloid kindling and seizure-induced decrease of muscarinic cholinergic receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 408-13. PMID 3973674  0.48
1985 McNamara JO, Bonhaus DW, Shin C, Crain BJ, Gellman RL, Giacchino JL. The kindling model of epilepsy: a critical review. Crc Critical Reviews in Clinical Neurobiology. 1: 341-91. PMID 3915977  0.6
1985 King GL, Dingledine R, Giacchino JL, McNamara JO. Abnormal neuronal excitability in hippocampal slices from kindled rats. Journal of Neurophysiology. 54: 1295-304. PMID 3001236  1
1985 Shin C, Pedersen HB, McNamara JO. gamma-Aminobutyric acid and benzodiazepine receptors in the kindling model of epilepsy: a quantitative radiohistochemical study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 2696-701. PMID 2995608  0.4
1985 Crain BJ, Valdes F, Chang KJ, McNamara JO. Autoradiographic localization of benzomorphan binding sites in rat brain. European Journal of Pharmacology. 113: 179-86. PMID 2995063 DOI: 10.1016/0014-2999(85)90734-4  0.4
1985 Iadarola MJ, Fanelli RJ, McNamara JO, Wilson WA. Comparison of the effects of diphenylbarbituric acid, phenobarbital, pentobarbital and secobarbital on GABA-mediated inhibition and benzodiazepine binding. The Journal of Pharmacology and Experimental Therapeutics. 232: 127-33. PMID 2981311  0.64
1984 Giacchino JL, Somjen GG, Frush DP, McNamara JO. Lateral entorhinal cortical kindling can be established without potentiation of the entorhinal-granule cell synapse. Experimental Neurology. 86: 483-92. PMID 6499989 DOI: 10.1016/0014-4886(84)90083-9  0.6
1984 McNamara JO, Galloway MT, Rigsbee LC, Shin C. Evidence implicating substantia nigra in regulation of kindled seizure threshold. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 2410-7. PMID 6481454  0.4
1984 Savage DD, Werling LL, Nadler JV, McNamara JO. Selective and reversible increase in the number of quisqualate-sensitive glutamate binding sites on hippocampal synaptic membranes after angular bundle kindling. Brain Research. 307: 332-5. PMID 6147176 DOI: 10.1016/0006-8993(84)90488-8  0.48
1984 Savage DD, Nadler JV, McNamara JO. Reduced kainic acid binding in rat hippocampal formation after limbic kindling. Brain Research. 323: 128-31. PMID 6098330 DOI: 10.1016/0006-8993(84)90274-9  0.48
1983 Savage DD, Dasheiff RM, McNamara JO. Kindled seizure-induced reduction of muscarinic cholinergic receptors in rat hippocampal formation: evidence for localization to dentate granule cells. The Journal of Comparative Neurology. 221: 106-12. PMID 6643742 DOI: 10.1002/cne.902210109  1
1983 Kraus VM, Dasheiff RM, Fanelli RJ, McNamara JO. Benzodiazepine receptor declines in hippocampal formation following limbic seizures. Brain Research. 277: 305-9. PMID 6315144 DOI: 10.1016/0006-8993(83)90938-1  1
1983 Fanelli RJ, McNamara JO. Kindled seizures result in decreased responsiveness of benzodiazepine receptors to gamma-aminobutyric acid (GABA). The Journal of Pharmacology and Experimental Therapeutics. 226: 147-50. PMID 6306222  0.64
1982 Dasheiff RM, Savage DD, McNamara JO. Seizures down-regulate muscarinic cholinergic receptors in hippocampal formation. Brain Research. 235: 327-34. PMID 7188331 DOI: 10.1016/0006-8993(82)91011-3  1
1982 Savage DD, McNamara JO. Kindled seizures selectively reduce a subpopulation of [3H]quinuclidinyl benzilate binding sites in rat dentate gyrus. The Journal of Pharmacology and Experimental Therapeutics. 222: 670-3. PMID 7108770  0.48
1982 Dasheiff RM, McNamara JO. Intradentate colchicine retards the development of amygdala kindling. Annals of Neurology. 11: 347-52. PMID 7103415 DOI: 10.1002/ana.410110405  1
1982 Dasheiff RM, McNamara JO. Electrolytic entorhinal lesions cause seizures. Brain Research. 231: 444-50. PMID 7055687 DOI: 10.1016/0006-8993(82)90381-X  1
1982 Valdes F, Dasheiff RM, Birmingham F, Crutcher KA, McNamara JO. Benzodiazepine receptor increases after repeated seizures: evidence for localization to dentate granule cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 193-7. PMID 6275387  1
1982 Savage DD, Werling LL, Nadler JV, McNamara JO. Selective increase in L-[3H]glutamate binding to a quisqualate-sensitive site on hippocampal synaptic membranes after angular bundle kindling. European Journal of Pharmacology. 85: 255-6. PMID 6129988 DOI: 10.1016/0014-2999(82)90479-4  0.48
1981 Dasheiff RM, Byrne MC, Patrone V, McNamara JO. Biochemical evidence of decreased muscarinic cholinergic neuronal communication following amygdala-kindled seizures. Brain Research. 206: 233-8. PMID 7470892 DOI: 10.1016/0006-8993(81)90123-2  1
1981 Valdes F, Fanelli RJ, McNamara JO. Barbiturate and GABA receptors coupled to benzodiazepine receptors in rat hippocampal formation: a radiohistochemical study. Life Sciences. 29: 1895-900. PMID 6273678 DOI: 10.1016/0024-3205(81)90521-X  0.64
1980 Dasheiff RM, McNamara JO. Evidence for an agonist independent down regulation of hippocampal muscarinic receptors in kindling. Brain Research. 195: 345-53. PMID 7397505 DOI: 10.1016/0006-8993(80)90070-0  1
1980 Byrne MC, Gottlieb R, McNamara JO. Amygdala kindling induces muscarinic cholinergic receptor declines in a highly specific distribution within the limbic system. Experimental Neurology. 69: 85-98. PMID 7389852 DOI: 10.1016/0014-4886(80)90145-4  0.48
1980 McNamara JO, Peper AM, Patrone V. Repeated seizures induce long-term increase in hippocampal benzodiazepine receptors. Proceedings of the National Academy of Sciences of the United States of America. 77: 3029-32. PMID 6930682  0.48
1980 McNamara JO, Byrne MC, Dasheiff RM, Fitz JG. The kindling model of epilepsy: a review. Progress in Neurobiology. 15: 139-59. PMID 6109361 DOI: 10.1016/0301-0082(80)90006-4  1
1977 McNamara JO, Appel SH. Biochemical approaches to dementia. Contemporary Neurology Series. 15: 155-68. PMID 144584  0.96
1977 McNamara JO, Appel SH. Myelin basic protein phosphatase activity in rat brain. Journal of Neurochemistry. 29: 27-35. PMID 69679  0.96
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