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Robert L. Macdonald - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
GABA, epilepsy
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Year Citation  Score
2023 Hernandez CC, Hu N, Shen W, Macdonald RL. Epileptic Encephalopathy Structural Variants Share Common Gating and Trafficking Defects. Biomolecules. 13. PMID 38136660 DOI: 10.3390/biom13121790  0.416
2023 Hernandez CC, Shen Y, Hu N, Shen W, Narayanan V, Ramsey K, He W, Zou L, Macdonald RL. Variants Associated with Febrile Seizures. Biomolecules. 13. PMID 36979350 DOI: 10.3390/biom13030414  0.358
2022 Catron MA, Howe RK, Besing GK, St John EK, Potesta CV, Gallagher MJ, Macdonald RL, Zhou C. Sleep slow-wave oscillations trigger seizures in a genetic epilepsy model of Dravet syndrome. Brain Communications. 5: fcac332. PMID 36632186 DOI: 10.1093/braincomms/fcac332  0.693
2022 Qu S, Jackson LG, Zhou C, Shen D, Shen W, Nwosu G, Howe R, Caltron M, Flamm C, Biven M, Kang JQ, Macdonald RL. Heterozygous GABA receptor β3 subunit N110D knock-in mice have epileptic spasms. Epilepsia. PMID 36495145 DOI: 10.1111/epi.17470  0.755
2021 Qu S, Zhou C, Howe R, Shen W, Huang X, Catron M, Hu N, Macdonald RL. The K328M substitution in the human GABA receptor gamma2 subunit causes GEFS+ and premature sudden death in knock-in mice. Neurobiology of Disease. 105296. PMID 33582225 DOI: 10.1016/j.nbd.2021.105296  0.791
2020 Shen D, Chen J, Liu D, Shen M, Wang X, Wu Y, Ke S, Macdonald RL, Zhang Q. The F343L allele causes spontaneous seizures in a novel transgenic zebrafish model that can be treated with suberanilohydroxamic acid (SAHA). Annals of Translational Medicine. 8: 1560. PMID 33437759 DOI: 10.21037/atm-20-3745  0.38
2020 Shen W, Poliquin S, Macdonald RL, Dong M, Kang JQ. Endoplasmic reticulum stress increases inflammatory cytokines in an epilepsy mouse model Gabrg2 knockin: A link between genetic and acquired epilepsy? Epilepsia. PMID 32944937 DOI: 10.1111/epi.16670  0.386
2020 Zhang CQ, Catron MA, Ding L, Hanna CM, Gallagher MJ, Macdonald RL, Zhou C. Impaired State-Dependent Potentiation of GABAergic Synaptic Currents Triggers Seizures in a Genetic Generalized Epilepsy Model. Cerebral Cortex (New York, N.Y. : 1991). PMID 32930324 DOI: 10.1093/Cercor/Bhaa256  0.739
2020 Qu S, Catron M, Zhou C, Janve V, Shen W, Howe RK, Macdonald RL. GABA receptor β3 subunit mutation D120N causes Lennox-Gastaut syndrome in knock-in mice. Brain Communications. 2: fcaa028. PMID 32467926 DOI: 10.1093/braincomms/fcaa028  0.751
2019 Shi YW, Zhang Q, Cai K, Poliquin S, Shen W, Winters N, Yi YH, Wang J, Hu N, Macdonald RL, Liao WP, Kang JQ. Synaptic clustering differences due to different GABRB3 mutations cause variable epilepsy syndromes. Brain : a Journal of Neurology. PMID 31435640 DOI: 10.1093/brain/awz250  0.46
2019 Zhang CQ, McMahon B, Dong H, Warner T, Shen W, Gallagher M, Macdonald RL, Kang JQ. Molecular basis for and chemogenetic modulation of comorbidities in GABRG2-deficient epilepsies. Epilepsia. PMID 31087664 DOI: 10.1111/Epi.15160  0.431
2019 Hernandez CC, XiangWei W, Hu N, Shen D, Shen W, Lagrange AH, Zhang Y, Dai L, Ding C, Sun Z, Hu J, Zhu H, Jiang Y, Macdonald RL. Altered inhibitory synapses in de novo GABRA5 and GABRA1 mutations associated with early onset epileptic encephalopathies. Brain : a Journal of Neurology. PMID 31056671 DOI: 10.1093/Brain/Awz123  0.451
2019 Hernandez CC, Macdonald RL. A Structural Look at GABA Receptor Mutations Linked to Epilepsy Syndromes. Brain Research. PMID 30851244 DOI: 10.1016/J.Brainres.2019.03.004  0.488
2018 Lagrange AH, Hu N, Macdonald RL. GABA beyond the synapse-defining the subtype-specific pharmacodynamics of nonsynaptic GABA receptors. The Journal of Physiology. PMID 30019335 DOI: 10.1113/JP276187  0.461
2018 Wang CH, Hernandez CC, Wu J, Zhou N, Hsu HY, Shen ML, Wang YC, Macdonald RL, Wu DC. A missense mutation A384P associated with human hyperekplexia reveals a desensitization site of glycine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29440552 DOI: 10.1523/Jneurosci.0674-16.2018  0.468
2017 Hernandez CC, Zhang Y, Hu N, Shen D, Shen W, Liu X, Kong W, Jiang Y, Macdonald RL. GABA A Receptor Coupling Junction and Pore GABRB3 Mutations are Linked to Early-Onset Epileptic Encephalopathy. Scientific Reports. 7: 15903. PMID 29162865 DOI: 10.1038/S41598-017-16010-3  0.472
2017 Huang X, Zhou C, Tian M, Kang JQ, Shen W, Verdier K, Pimenta A, MacDonald RL. Overexpressing wild-type γ2 subunits rescued the seizure phenotype in Gabrg2(+/Q390X) Dravet syndrome mice. Epilepsia. PMID 28586508 DOI: 10.1111/Epi.13810  0.806
2017 Hernandez CC, Kong W, Hu N, Zhang Y, Shen W, Jackson L, Liu X, Jiang Y, Macdonald RL. Altered Channel Conductance States and Gating of GABAA Receptors by a Pore Mutation Linked to Dravet Syndrome. Eneuro. 4. PMID 28197552 DOI: 10.1523/ENEURO.0251-16.2017  0.426
2016 Hernandez CC, Klassen TL, Jackson LG, Gurba K, Hu N, Noebels JL, Macdonald RL. Correction: Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population. Plos One. 11: e0167264. PMID 27870904 DOI: 10.1371/journal.pone.0167264  0.777
2016 Shen D, Hernandez CC, Shen W, Hu N, Poduri A, Shiedley B, Rotenberg A, Datta AN, Leiz S, Patzer S, Boor R, Ramsey K, Goldberg E, Helbig I, Ortiz-Gonzalez XR, ... ... Macdonald RL, et al. De novo GABRG2 mutations associated with epileptic encephalopathies. Brain : a Journal of Neurology. PMID 27864268 DOI: 10.1093/Brain/Aww272  0.488
2016 Ishii A, Kang JQ, Schornak CC, Hernandez CC, Shen W, Watkins JC, Macdonald RL, Hirose S. A de novo missense mutation of GABRB2 causes early myoclonic encephalopathy. Journal of Medical Genetics. PMID 27789573 DOI: 10.1136/Jmedgenet-2016-104083  0.325
2016 Wang J, Shen D, Xia G, Shen W, Macdonald RL, Xu D, Kang JQ. Differential protein structural disturbances and suppression of assembly partners produced by nonsense GABRG2 epilepsy mutations: implications for disease phenotypic heterogeneity. Scientific Reports. 6: 35294. PMID 27762395 DOI: 10.1038/srep35294  0.46
2016 Hernandez CC, Klassen TL, Jackson LG, Gurba K, Hu N, Noebels JL, Macdonald RL. Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population. Plos One. 11: e0162883. PMID 27622563 DOI: 10.1371/Journal.Pone.0162883  0.816
2016 Botzolakis EJ, Gurba KN, Lagrange AH, Feng HJ, Stanic AK, Hu N, Macdonald RL. Comparison of GABA-A Receptor αβγ and αβδ Expression Using Flow Cytometry and Electrophysiology: Evidence for Alternate Subunit Stoichiometries and Arrangements. The Journal of Biological Chemistry. PMID 27493204 DOI: 10.1074/Jbc.M115.698860  0.795
2016 Kang JQ, Macdonald RL. Molecular Pathogenic Basis for GABRG2 Mutations Associated With a Spectrum of Epilepsy Syndromes, From Generalized Absence Epilepsy to Dravet Syndrome. Jama Neurology. PMID 27367160 DOI: 10.1001/jamaneurol.2016.0449  0.382
2016 Warner TA, Shen W, Huang X, Liu Z, Macdonald RL, Kang JQ. DIfferential molecular and behavioral alterations in mouse models of GABRG2 haploinsufficiency versus dominant negative mutations associated with human epilepsy. Human Molecular Genetics. PMID 27340224 DOI: 10.1093/Hmg/Ddw168  0.546
2016 Janve VS, Hernandez CC, Verdier KM, Hu N, Macdonald RL. Epileptic encephalopathy de novo GABRB mutations impair GABAA receptor function. Annals of Neurology. PMID 26950270 DOI: 10.1002/Ana.24631  0.433
2015 Kang JQ, Shen W, Zhou C, Xu D, Macdonald RL. The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration. Nature Neuroscience. 18: 988-96. PMID 26005849 DOI: 10.1038/Nn.4024  0.777
2014 Todd E, Gurba KN, Botzolakis EJ, Stanic AK, Macdonald RL. GABAA receptor biogenesis is impaired by the γ2 subunit febrile seizure-associated mutation, GABRG2(R177G). Neurobiology of Disease. 69: 215-24. PMID 24874541 DOI: 10.1016/j.nbd.2014.05.013  0.825
2014 Huang X, Hernandez CC, Hu N, Macdonald RL. Three epilepsy-associated GABRG2 missense mutations at the γ+/β- interface disrupt GABAA receptor assembly and trafficking by similar mechanisms but to different extents. Neurobiology of Disease. 68: 167-79. PMID 24798517 DOI: 10.1016/J.Nbd.2014.04.015  0.609
2014 Johnston AJ, Kang JQ, Shen W, Pickrell WO, Cushion TD, Davies JS, Baer K, Mullins JG, Hammond CL, Chung SK, Thomas RH, White C, Smith PE, Macdonald RL, Rees MI. A novel GABRG2 mutation, p.R136*, in a family with GEFS+ and extended phenotypes. Neurobiology of Disease. 64: 131-41. PMID 24407264 DOI: 10.1016/J.Nbd.2013.12.013  0.408
2014 Lo WY, Lagrange AH, Hernandez CC, Gurba KN, Macdonald RL. Co-expression of γ2 subunits hinders processing of N-linked glycans attached to the N104 glycosylation sites of GABAA receptor β2 subunits. Neurochemical Research. 39: 1088-103. PMID 24213971 DOI: 10.1007/S11064-013-1187-9  0.821
2013 Kang JQ, Shen W, Macdonald RL. Trafficking-deficient mutant GABRG2 subunit amount may modify epilepsy phenotype. Annals of Neurology. 74: 547-59. PMID 23720301 DOI: 10.1002/ana.23947  0.432
2013 Tian M, Mei D, Freri E, Hernandez CC, Granata T, Shen W, Macdonald RL, Guerrini R. Impaired surface αβγ GABA(A) receptor expression in familial epilepsy due to a GABRG2 frameshift mutation. Neurobiology of Disease. 50: 135-41. PMID 23069679 DOI: 10.1016/J.Nbd.2012.10.008  0.708
2013 Hernandez CC, Gurba KN, Hu N, Macdonald RL. GAbAA Receptor Subunit Rare Variants Identified in Patients with Idiopathic Generalized Epilepsy Alter Receptor Gating and Assembly Biophysical Journal. 104: 275a. DOI: 10.1016/J.Bpj.2012.11.1541  0.825
2012 Macdonald RL, Kang JQ. mRNA surveillance and endoplasmic reticulum quality control processes alter biogenesis of mutant GABAA receptor subunits associated with genetic epilepsies. Epilepsia. 53: 59-70. PMID 23216579 DOI: 10.1111/epi.12035  0.525
2012 Porter RJ, Dhir A, Macdonald RL, Rogawski MA. Mechanisms of action of antiseizure drugs. Handbook of Clinical Neurology. 108: 663-81. PMID 22939059 DOI: 10.1016/B978-0-444-52899-5.00021-6  0.369
2012 Huang X, Tian M, Hernandez CC, Hu N, Macdonald RL. The GABRG2 nonsense mutation, Q40X, associated with Dravet syndrome activated NMD and generated a truncated subunit that was partially rescued by aminoglycoside-induced stop codon read-through. Neurobiology of Disease. 48: 115-23. PMID 22750526 DOI: 10.1016/J.Nbd.2012.06.013  0.753
2012 Wu X, Wu Z, Ning G, Guo Y, Ali R, Macdonald RL, De Blas AL, Luscher B, Chen G. γ-Aminobutyric acid type A (GABAA) receptor α subunits play a direct role in synaptic versus extrasynaptic targeting. The Journal of Biological Chemistry. 287: 27417-30. PMID 22711532 DOI: 10.1074/Jbc.M112.360461  0.482
2012 Tian M, Macdonald RL. The intronic GABRG2 mutation, IVS6+2T->G, associated with childhood absence epilepsy altered subunit mRNA intron splicing, activated nonsense-mediated decay, and produced a stable truncated γ2 subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5937-52. PMID 22539854 DOI: 10.1523/JNEUROSCI.5332-11.2012  0.669
2012 Gurba KN, Hernandez CC, Hu N, Macdonald RL. GABRB3 mutation, G32R, associated with childhood absence epilepsy alters α1β3γ2L γ-aminobutyric acid type A (GABAA) receptor expression and channel gating. The Journal of Biological Chemistry. 287: 12083-97. PMID 22303015 DOI: 10.1074/Jbc.M111.332528  0.84
2012 Hernandez CC, Gurba KN, Hu N, Macdonald RL. Mapping GABAA Receptor Single Nucleotide Polymorphisms (SNPs) Linked to Epilepsy: Insights into the Receptor Gating and Assembly Biophysical Journal. 102: 111a. DOI: 10.1016/J.Bpj.2011.11.624  0.818
2011 Hernandez CC, Gurba KN, Hu N, Macdonald RL. The GABRA6 mutation, R46W, associated with childhood absence epilepsy, alters 6β22 and 6β2 GABA(A) receptor channel gating and expression. The Journal of Physiology. 589: 5857-78. PMID 21930603 DOI: 10.1113/Jphysiol.2011.218883  0.845
2011 Botzolakis EJ, Zhao J, Gurba KN, Macdonald RL, Hedera P. The effect of HSP-causing mutations in SPG3A and NIPA1 on the assembly, trafficking, and interaction between atlastin-1 and NIPA1. Molecular and Cellular Neurosciences. 46: 122-35. PMID 20816793 DOI: 10.1016/j.mcn.2010.08.012  0.771
2011 Delahanty RJ, Kang JQ, Brune CW, Kistner EO, Courchesne E, Cox NJ, Cook EH, Macdonald RL, Sutcliffe JS. Maternal transmission of a rare GABRB3 signal peptide variant is associated with autism. Molecular Psychiatry. 16: 86-96. PMID 19935738 DOI: 10.1038/Mp.2009.118  0.388
2011 Hernandez CC, Gurba KN, Hu N, Macdonald RL. A novel Polymorphism Linked to Epilepsy Encoding a Missense Mutation in the Pre-M1 Region of a6 Subunits Alters the Gating, but not Trafficking, of GABAa Receptors Biophysical Journal. 100: 271a-272a. DOI: 10.1016/J.Bpj.2010.12.1692  0.835
2010 Kang JQ, Shen W, Lee M, Gallagher MJ, Macdonald RL. Slow degradation and aggregation in vitro of mutant GABAA receptor gamma2(Q351X) subunits associated with epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13895-905. PMID 20943930 DOI: 10.1523/JNEUROSCI.2320-10.2010  0.439
2010 Lo WY, Lagrange AH, Hernandez CC, Harrison R, Dell A, Haslam SM, Sheehan JH, Macdonald RL. Glycosylation of {beta}2 subunits regulates GABAA receptor biogenesis and channel gating. The Journal of Biological Chemistry. 285: 31348-61. PMID 20639197 DOI: 10.1074/Jbc.M110.151449  0.497
2010 Ding L, Feng HJ, Macdonald RL, Botzolakis EJ, Hu N, Gallagher MJ. GABA(A) receptor alpha1 subunit mutation A322D associated with autosomal dominant juvenile myoclonic epilepsy reduces the expression and alters the composition of wild type GABA(A) receptors. The Journal of Biological Chemistry. 285: 26390-405. PMID 20551311 DOI: 10.1074/Jbc.M110.142299  0.808
2010 Feng HJ, Macdonald RL. Barbiturates require the N terminus and first transmembrane domain of the delta subunit for enhancement of alpha1beta3delta GABAA receptor currents. The Journal of Biological Chemistry. 285: 23614-21. PMID 20525684 DOI: 10.1074/Jbc.M110.122564  0.505
2010 Macdonald RL, Kang JQ, Gallagher MJ. Mutations in GABAA receptor subunits associated with genetic epilepsies. The Journal of Physiology. 588: 1861-9. PMID 20308251 DOI: 10.1113/jphysiol.2010.186999  0.439
2010 Tang X, Hernandez CC, Macdonald RL. Modulation of spontaneous and GABA-evoked tonic alpha4beta3delta and alpha4beta3gamma2L GABAA receptor currents by protein kinase A. Journal of Neurophysiology. 103: 1007-19. PMID 19939957 DOI: 10.1152/Jn.00801.2009  0.594
2010 MacDonald RL, Kang JQ, Gallagher MJ. Genetic epilepsies and GABAA receptor mutations Epilepsia. 51: 64. DOI: 10.1111/j.1528-1167.2010.02850.x  0.519
2010 Macdonald RL, Botzolakis EJ. GABAA receptor channels Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. 257-282. DOI: 10.1016/B978-0-12-374373-2.00014-5  0.769
2009 Belelli D, Harrison NL, Maguire J, Macdonald RL, Walker MC, Cope DW. Extrasynaptic GABAA receptors: form, pharmacology, and function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12757-63. PMID 19828786 DOI: 10.1523/Jneurosci.3340-09.2009  0.489
2009 Kang JQ, Macdonald RL. Making sense of nonsense GABA(A) receptor mutations associated with genetic epilepsies. Trends in Molecular Medicine. 15: 430-8. PMID 19717338 DOI: 10.1016/j.molmed.2009.07.003  0.511
2009 Bianchi MT, Botzolakis EJ, Lagrange AH, Macdonald RL. Benzodiazepine modulation of GABA(A) receptor opening frequency depends on activation context: a patch clamp and simulation study. Epilepsy Research. 85: 212-20. PMID 19447010 DOI: 10.1016/j.eplepsyres.2009.03.007  0.83
2009 Lewis AS, Schwartz E, Chan CS, Noam Y, Shin M, Wadman WJ, Surmeier DJ, Baram TZ, Macdonald RL, Chetkovich DM. Alternatively spliced isoforms of TRIP8b differentially control h channel trafficking and function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6250-65. PMID 19439603 DOI: 10.1523/Jneurosci.0856-09.2009  0.331
2009 Macdonald RL, Kang JQ. Molecular pathology of genetic epilepsies associated with GABAA receptor subunit mutations. Epilepsy Currents / American Epilepsy Society. 9: 18-23. PMID 19396344 DOI: 10.1111/j.1535-7511.2008.01278.x  0.468
2009 Kang JQ, Shen W, Macdonald RL. The GABRG2 mutation, Q351X, associated with generalized epilepsy with febrile seizures plus, has both loss of function and dominant-negative suppression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2845-56. PMID 19261880 DOI: 10.1523/JNEUROSCI.4772-08.2009  0.463
2009 Kang JQ, Shen W, Macdonald RL. Two molecular pathways (NMD and ERAD) contribute to a genetic epilepsy associated with the GABA(A) receptor GABRA1 PTC mutation, 975delC, S326fs328X. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2833-44. PMID 19261879 DOI: 10.1523/JNEUROSCI.4512-08.2009  0.457
2009 Botzolakis EJ, Maheshwari A, Feng HJ, Lagrange AH, Shaver JH, Kassebaum NJ, Venkataraman R, Baudenbacher F, Macdonald RL. Achieving synaptically relevant pulses of neurotransmitter using PDMS microfluidics. Journal of Neuroscience Methods. 177: 294-302. PMID 19013195 DOI: 10.1016/j.jneumeth.2008.10.014  0.784
2009 Feng HJ, Botzolakis EJ, Macdonald RL. Context-dependent modulation of alphabetagamma and alphabetadelta GABA A receptors by penicillin: implications for phasic and tonic inhibition. Neuropharmacology. 56: 161-73. PMID 18775733 DOI: 10.1016/J.Neuropharm.2008.08.010  0.826
2008 Zhao J, Matthies DS, Botzolakis EJ, Macdonald RL, Blakely RD, Hedera P. Hereditary spastic paraplegia-associated mutations in the NIPA1 gene and its Caenorhabditis elegans homolog trigger neural degeneration in vitro and in vivo through a gain-of-function mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13938-51. PMID 19091982 DOI: 10.1523/JNEUROSCI.4668-08.2008  0.769
2008 Lo WY, Botzolakis EJ, Tang X, Macdonald RL. A conserved Cys-loop receptor aspartate residue in the M3-M4 cytoplasmic loop is required for GABAA receptor assembly. The Journal of Biological Chemistry. 283: 29740-52. PMID 18723504 DOI: 10.1074/Jbc.M802856200  0.815
2008 Rula EY, Lagrange AH, Jacobs MM, Hu N, Macdonald RL, Emeson RB. Developmental modulation of GABA(A) receptor function by RNA editing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6196-201. PMID 18550761 DOI: 10.1523/Jneurosci.0443-08.2008  0.482
2008 Tanaka M, Olsen RW, Medina MT, Schwartz E, Alonso ME, Duron RM, Castro-Ortega R, Martinez-Juarez IE, Pascual-Castroviejo I, Machado-Salas J, Silva R, Bailey JN, Bai D, Ochoa A, Jara-Prado A, ... ... Macdonald RL, et al. Hyperglycosylation and reduced GABA currents of mutated GABRB3 polypeptide in remitting childhood absence epilepsy. American Journal of Human Genetics. 82: 1249-61. PMID 18514161 DOI: 10.1016/j.ajhg.2008.04.020  0.446
2008 Feng HJ, Mathews GC, Kao C, Macdonald RL. Alterations of GABA A-receptor function and allosteric modulation during development of status epilepticus. Journal of Neurophysiology. 99: 1285-93. PMID 18216225 DOI: 10.1152/Jn.01180.2007  0.431
2007 Bianchi MT, Botzolakis EJ, Haas KF, Fisher JL, Macdonald RL. Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABAA receptor desensitization and deactivation. The Journal of Physiology. 584: 769-87. PMID 17884921 DOI: 10.1113/jphysiol.2007.142364  0.819
2007 Gallagher MJ, Ding L, Maheshwari A, Macdonald RL. The GABAA receptor alpha1 subunit epilepsy mutation A322D inhibits transmembrane helix formation and causes proteasomal degradation. Proceedings of the National Academy of Sciences of the United States of America. 104: 12999-3004. PMID 17670950 DOI: 10.1073/pnas.0700163104  0.357
2007 Lagrange AH, Botzolakis EJ, Macdonald RL. Enhanced macroscopic desensitization shapes the response of alpha4 subtype-containing GABAA receptors to synaptic and extrasynaptic GABA. The Journal of Physiology. 578: 655-76. PMID 17124266 DOI: 10.1113/jphysiol.2006.122135  0.826
2006 Macdonald RL, Kang JQ, Gallagher MJ, Feng HJ. GABA(A) receptor mutations associated with generalized epilepsies. Advances in Pharmacology (San Diego, Calif.). 54: 147-69. PMID 17175814 DOI: 10.1016/S1054-3589(06)54007-4  0.548
2006 Audenaert D, Schwartz E, Claeys KG, Claes L, Deprez L, Suls A, Van Dyck T, Lagae L, Van Broeckhoven C, Macdonald RL, De Jonghe P. A novel GABRG2 mutation associated with febrile seizures. Neurology. 67: 687-90. PMID 16924025 DOI: 10.1212/01.wnl.0000230145.73496.a2  0.437
2006 Kang JQ, Shen W, Macdonald RL. Why does fever trigger febrile seizures? GABAA receptor gamma2 subunit mutations associated with idiopathic generalized epilepsies have temperature-dependent trafficking deficiencies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2590-7. PMID 16510738 DOI: 10.1523/JNEUROSCI.4243-05.2006  0.457
2006 Feng HJ, Kang JQ, Song L, Dibbens L, Mulley J, Macdonald RL. Delta subunit susceptibility variants E177A and R220H associated with complex epilepsy alter channel gating and surface expression of alpha4beta2delta GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1499-506. PMID 16452673 DOI: 10.1523/Jneurosci.2913-05.2006  0.475
2005 Jones-Davis DM, Song L, Gallagher MJ, Macdonald RL. Structural determinants of benzodiazepine allosteric regulation of GABA(A) receptor currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8056-65. PMID 16135763 DOI: 10.1523/JNEUROSCI.0348-05.2005  0.808
2005 Gallagher MJ, Shen W, Song L, Macdonald RL. Endoplasmic reticulum retention and associated degradation of a GABAA receptor epilepsy mutation that inserts an aspartate in the M3 transmembrane segment of the alpha1 subunit. The Journal of Biological Chemistry. 280: 37995-8004. PMID 16123039 DOI: 10.1074/jbc.M508305200  0.354
2005 Rogawski MA, Macdonald RL, Pedley TA. Larry S. Benardo, MD, PhD 1956–2004 Epilepsy Currents. 5: 159-159. DOI: 10.1111/j.1535-7597.2005.20050704.x  0.345
2005 Macdonald RL, Bianchi MT, Feng H. Corrigendum to “Mutations linked to generalized epilepsy in humans reduce GABAA receptor current” [Exp. Neurol. 184 (2003) S58–S67] Experimental Neurology. 191: 223. DOI: 10.1016/J.Expneurol.2004.08.029  0.626
2004 Karadsheh MS, Shah MS, Tang X, Macdonald RL, Stitzel JA. Functional characterization of mouse alpha4beta2 nicotinic acetylcholine receptors stably expressed in HEK293T cells. Journal of Neurochemistry. 91: 1138-50. PMID 15569257 DOI: 10.1111/J.1471-4159.2004.02801.X  0.505
2004 Kang JQ, Kang J, Macdonald RL. The GABAA receptor gamma2 subunit R43Q mutation linked to childhood absence epilepsy and febrile seizures causes retention of alpha1beta2gamma2S receptors in the endoplasmic reticulum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8672-7. PMID 15470132 DOI: 10.1523/JNEUROSCI.2717-04.2004  0.526
2004 Macdonald RL, Gallagher MJ, Feng HJ, Kang J. GABA(A) receptor epilepsy mutations. Biochemical Pharmacology. 68: 1497-506. PMID 15451392 DOI: 10.1016/J.Bcp.2004.07.029  0.512
2004 Feng HJ, Macdonald RL. Multiple actions of propofol on alphabetagamma and alphabetadelta GABAA receptors. Molecular Pharmacology. 66: 1517-24. PMID 15331770 DOI: 10.1124/Mol.104.003426  0.488
2004 Feng HJ, Bianchi MT, Macdonald RL. Pentobarbital differentially modulates alpha1beta3delta and alpha1beta3gamma2L GABAA receptor currents. Molecular Pharmacology. 66: 988-1003. PMID 15247320 DOI: 10.1124/Mol.104.002543  0.704
2004 Gallagher MJ, Song L, Arain F, Macdonald RL. The juvenile myoclonic epilepsy GABA(A) receptor alpha1 subunit mutation A322D produces asymmetrical, subunit position-dependent reduction of heterozygous receptor currents and alpha1 subunit protein expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5570-8. PMID 15201329 DOI: 10.1523/JNEUROSCI.1301-04.2004  0.388
2004 Feng HJ, Macdonald RL. Proton modulation of alpha 1 beta 3 delta GABAA receptor channel gating and desensitization. Journal of Neurophysiology. 92: 1577-85. PMID 15152020 DOI: 10.1152/Jn.00285.2004  0.505
2004 Dibbens LM, Feng HJ, Richards MC, Harkin LA, Hodgson BL, Scott D, Jenkins M, Petrou S, Sutherland GR, Scheffer IE, Berkovic SF, Macdonald RL, Mulley JC. GABRD encoding a protein for extra- or peri-synaptic GABAA receptors is a susceptibility locus for generalized epilepsies. Human Molecular Genetics. 13: 1315-9. PMID 15115768 DOI: 10.1093/Hmg/Ddh146  0.504
2003 Hinkle DJ, Macdonald RL. Beta subunit phosphorylation selectively increases fast desensitization and prolongs deactivation of alpha1beta1gamma2L and alpha1beta3gamma2L GABA(A) receptor currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11698-710. PMID 14684872  0.815
2003 Bianchi MT, Macdonald RL. Neurosteroids shift partial agonist activation of GABA(A) receptor channels from low- to high-efficacy gating patterns. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10934-43. PMID 14645489 DOI: 10.1523/Jneurosci.23-34-10934.2003  0.692
2003 Macdonald RL, Bianchi MT, Bianch MT, Feng H. Mutations linked to generalized epilepsy in humans reduce GABA(A) receptor current. Experimental Neurology. 184: S58-67. PMID 14597328 DOI: 10.1016/J.Expneurol.2003.08.011  0.713
2003 Kim H, Macdonald RL. An N-terminal histidine is the primary determinant of alpha subunit-dependent Cu2+ sensitivity of alphabeta3gamma2L GABA(A) receptors. Molecular Pharmacology. 64: 1145-52. PMID 14573764 DOI: 10.1124/mol.64.5.1145  0.35
2003 Hinkle DJ, Bianchi MT, Macdonald RL. Modifications of a commercial perfusion system for use in ultrafast solution exchange during patch clamp recording. Biotechniques. 35: 472-4, 476. PMID 14513550  0.758
2003 Kim H, Flanagin BA, Qin C, Macdonald RL, Stitzel JA. The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity alpha 4 beta 2 nAChRs. Neuropharmacology. 45: 345-54. PMID 12871652 DOI: 10.1016/S0028-3908(03)00167-9  0.398
2003 Jones-Davis DM, Macdonald RL. GABA(A) receptor function and pharmacology in epilepsy and status epilepticus. Current Opinion in Pharmacology. 3: 12-8. PMID 12550736 DOI: 10.1016/S1471-4892(02)00015-2  0.828
2003 Hinkle DJ, Macdonald RL. β Subunit Phosphorylation Selectively Increases Fast Desensitization and Prolongs Deactivation of α1β1γ2L and α1β3γ2L GABAAReceptor Currents The Journal of Neuroscience. 23: 11698-11710. DOI: 10.1523/JNEUROSCI.23-37-11698.2003  0.81
2002 Chen C, Bharucha V, Chen Y, Westenbroek RE, Brown A, Malhotra JD, Jones D, Avery C, Gillespie PJ, Kazen-Gillespie KA, Kazarinova-Noyes K, Shrager P, Saunders TL, Macdonald RL, Ransom BR, et al. Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits. Proceedings of the National Academy of Sciences of the United States of America. 99: 17072-7. PMID 12481039 DOI: 10.1073/Pnas.212638099  0.363
2002 Bianchi MT, Haas KF, Macdonald RL. Alpha1 and alpha6 subunits specify distinct desensitization, deactivation and neurosteroid modulation of GABA(A) receptors containing the delta subunit. Neuropharmacology. 43: 492-502. PMID 12367596 DOI: 10.1016/S0028-3908(02)00163-6  0.71
2002 Bianchi MT, Macdonald RL. Slow phases of GABA(A) receptor desensitization: structural determinants and possible relevance for synaptic function. The Journal of Physiology. 544: 3-18. PMID 12356876 DOI: 10.1113/jphysiol.2002.020255  0.694
2002 Jones DM, Esmaeil N, Maren S, Macdonald RL. Characterization of pharmacoresistance to benzodiazepines in the rat Li-pilocarpine model of status epilepticus. Epilepsy Research. 50: 301-12. PMID 12200221 DOI: 10.1016/S0920-1211(02)00085-2  0.36
2002 Buhr A, Bianchi MT, Baur R, Courtet P, Pignay V, Boulenger JP, Gallati S, Hinkle DJ, Macdonald RL, Sigel E. Functional characterization of the new human GABA(A) receptor mutation beta3(R192H). Human Genetics. 111: 154-60. PMID 12189488 DOI: 10.1007/s00439-002-0766-7  0.824
2002 Bianchi MT, Song L, Zhang H, Macdonald RL. Two different mechanisms of disinhibition produced by GABAA receptor mutations linked to epilepsy in humans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5321-7. PMID 12097483 DOI: 10.1523/Jneurosci.22-13-05321.2002  0.719
2002 Greenfield LJ, Zaman SH, Sutherland ML, Lummis SC, Niemeyer MI, Barnard EA, Macdonald RL. Mutation of the GABAA receptor M1 transmembrane proline increases GABA affinity and reduces barbiturate enhancement. Neuropharmacology. 42: 502-21. PMID 11955521 DOI: 10.1016/S0028-3908(01)00196-4  0.467
2002 Wohlfarth KM, Bianchi MT, Macdonald RL. Enhanced neurosteroid potentiation of ternary GABA(A) receptors containing the delta subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1541-9. PMID 11880484 DOI: 10.1523/Jneurosci.22-05-01541.2002  0.706
2002 Wohlfarth KM, Bianchi MT, Macdonald RL. Enhanced Neurosteroid Potentiation of Ternary GABAAReceptors Containing the δ Subunit The Journal of Neuroscience. 22: 1541-1549. DOI: 10.1523/JNEUROSCI.22-05-01541.2002  0.579
2001 Macdonald RL. GABAA Receptor Defects Can Cause Epilepsy. Epilepsy Currents / American Epilepsy Society. 1: 74. PMID 15309196 DOI: 10.1046/j.1535-7597.2001.00018.x  0.389
2001 Bianchi MT, Macdonald RL. Agonist Trapping by GABAA Receptor Channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9083-91. PMID 11717341 DOI: 10.1523/Jneurosci.21-23-09083.2001  0.69
2001 Bianchi MT, Macdonald RL. Mutation of the 9' leucine in the GABA(A) receptor gamma2L subunit produces an apparent decrease in desensitization by stabilizing open states without altering desensitized states. Neuropharmacology. 41: 737-44. PMID 11640928 DOI: 10.1016/S0028-3908(01)00132-0  0.676
2001 Nagaya N, Macdonald RL. Two gamma2L subunit domains confer low Zn2+ sensitivity to ternary GABA(A) receptors. The Journal of Physiology. 532: 17-30. PMID 11283222 DOI: 10.1111/J.1469-7793.2001.0017G.X  0.613
2001 Bianchi MT, Haas KF, Macdonald RL. Structural determinants of fast desensitization and desensitization-deactivation coupling in GABAa receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1127-36. PMID 11160383 DOI: 10.1523/Jneurosci.21-04-01127.2001  0.749
2000 Neelands TR, King AP, Macdonald RL. Functional expression of L-, N-, P/Q-, and R-type calcium channels in the human NT2-N cell line. Journal of Neurophysiology. 84: 2933-44. PMID 11110822 DOI: 10.1152/Jn.2000.84.6.2933  0.361
2000 Fisher JL, Hinkle DJ, Macdonald RL. Loreclezole inhibition of recombinant alpha1beta1gamma2L GABA(A) receptor single channel currents. Neuropharmacology. 39: 235-45. PMID 10670419 DOI: 10.1016/S0028-3908(99)00108-2  0.832
1999 Burgard EC, Haas KF, Macdonald RL. Channel properties determine the transient activation kinetics of recombinant GABA(A) receptors. Brain Research. Molecular Brain Research. 73: 28-36. PMID 10581395 DOI: 10.1016/S0169-328X(99)00230-2  0.626
1999 MacDonald RL, Kapur J. Pharmacological properties of recombinant and hippocampal dentate granule cell GABAA receptors. Advances in Neurology. 79: 979-90. PMID 10514880  0.555
1999 Neelands TR, Macdonald RL. Incorporation of the π subunit into functional γ-aminobutyric acid(A) receptors Molecular Pharmacology. 56: 598-610. PMID 10462548 DOI: 10.1124/MOL.56.3.598  0.496
1999 Neelands TR, Zhang J, Macdonald RL. GABA(A) receptors expressed in undifferentiated human teratocarcinoma NT2 cells differ from those expressed by differentiated NT2-N cells Journal of Neuroscience. 19: 7057-7065. PMID 10436060 DOI: 10.1523/Jneurosci.19-16-07057.1999  0.495
1999 Macdonald RL, Kapur J. Acute cellular alterations in the hippocampus after status epilepticus. Epilepsia. 40: S9-20; discussion S2. PMID 10421557 DOI: 10.1111/J.1528-1157.1999.Tb00873.X  0.643
1999 Kapur J, Haas KF, Macdonald RL. Physiological properties of GABAA receptors from acutely dissociated rat dentate granule cells. Journal of Neurophysiology. 81: 2464-71. PMID 10322081 DOI: 10.1152/Jn.1999.81.5.2464  0.737
1999 Tietz EI, Kapur J, Macdonald RL. Functional GABAA receptor heterogeneity of acutely dissociated hippocampal CA1 pyramidal cells. Journal of Neurophysiology. 81: 1575-86. PMID 10200193 DOI: 10.1152/Jn.1999.81.4.1575  0.646
1999 Kapur J, Macdonald RL. Postnatal development of hippocampal dentate granule cell gamma-aminobutyric acidA receptor pharmacological properties. Molecular Pharmacology. 55: 444-52. PMID 10051527  0.576
1999 Neelands TR, Fisher JL, Bianchi M, Macdonald RL. Spontaneous and gamma-aminobutyric acid (GABA)-activated GABA(A) receptor channels formed by epsilon subunit-containing isoforms. Molecular Pharmacology. 55: 168-78. PMID 9882711 DOI: 10.1124/Mol.55.1.168  0.761
1999 Haas KF, Macdonald RL. GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts. The Journal of Physiology. 514: 27-45. PMID 9831714 DOI: 10.1111/J.1469-7793.1999.027Af.X  0.589
1999 Coulter DA, Sloviter RS, Macdonald RL. Panel discussion: Discussion and questions from the audience Epilepsia. 40: S40-S41. DOI: 10.1111/j.1528-1157.1999.tb00877.x  0.475
1999 Macdonald RL. Introduction and symposium overview Epilepsia. 40: S1-S2. DOI: 10.1111/J.1528-1157.1999.Tb00871.X  0.322
1999 Haas KF, Macdonald RL. GABA(A) receptor subunit γ2 and δ subtypes confer unique kinetic properties on recombinant GABA(A) receptor currents in mouse fibroblasts Journal of Physiology. 514: 27-45. DOI: 10.1111/j.1469-7793.1999.027af.x  0.606
1998 Fisher JL, Macdonald RL. The role of an alpha subtype M2-M3 His in regulating inhibition of GABAA receptor current by zinc and other divalent cations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2944-53. PMID 9526011 DOI: 10.1523/Jneurosci.18-08-02944.1998  0.59
1998 Neelands TR, Greenfield LJ, Zhang J, Turner RS, Macdonald RL. GABAAReceptor Pharmacology and Subtype mRNA Expression in Human Neuronal NT2-N Cells The Journal of Neuroscience. 18: 4993-5007. DOI: 10.1523/JNEUROSCI.18-13-04993.1998  0.432
1997 Fisher JL, Macdonald RL. Functional properties of recombinant GABA(A) receptors composed of single or multiple beta subunit subtypes. Neuropharmacology. 36: 1601-10. PMID 9517431 DOI: 10.1016/S0028-3908(97)00133-0  0.607
1997 Fisher JL, Macdonald RL. Single channel properties of recombinant GABAA receptors containing gamma 2 or delta subtypes expressed with alpha 1 and beta 3 subtypes in mouse L929 cells. The Journal of Physiology. 505: 283-97. PMID 9423172 DOI: 10.1111/j.1469-7793.1997.283bb.x  0.558
1997 Fisher JL, Zhang J, Macdonald RL. The role of alpha1 and alpha6 subtype amino-terminal domains in allosteric regulation of gamma-aminobutyric acida receptors. Molecular Pharmacology. 52: 714-24. PMID 9380035 DOI: 10.1124/MOL.52.4.714  0.598
1997 Kapur J, Macdonald RL. Rapid seizure-induced reduction of benzodiazepine and Zn2+ sensitivity of hippocampal dentate granule cell GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7532-40. PMID 9295398 DOI: 10.1523/Jneurosci.17-19-07532.1997  0.612
1997 Saxena NC, Neelands TR, MacDonald RL. Contrasting actions of lanthanum on different recombinant gamma-aminobutyric acid receptor isoforms expressed in L929 fibroblasts. Molecular Pharmacology. 51: 328-35. PMID 9203639 DOI: 10.1124/MOL.51.2.328  0.469
1997 Macdonald RL, Greenfield LJ. Mechanisms of action of new antiepileptic drugs. Current Opinion in Neurology. 10: 121-8. PMID 9147003 DOI: 10.1097/00019052-199704000-00009  0.377
1997 Greenfield LJ, Sun F, Neelands TR, Burgard EC, Donnelly JL, MacDonald RL. Expression of functional GABAA receptors in transfected L929 cells isolated by immunomagnetic bead separation. Neuropharmacology. 36: 63-73. PMID 9144642 DOI: 10.1016/S0028-3908(96)00150-5  0.399
1997 Wiley JW, Moises HC, Gross RA, MacDonald RL. Dynorphin A-mediated reduction in multiple calcium currents involves a G(o) alpha-subtype G protein in rat primary afferent neurons. Journal of Neurophysiology. 77: 1338-48. PMID 9084601 DOI: 10.1152/Jn.1997.77.3.1338  0.48
1997 Donnelly JL, MacDonald RL. Loreclezole enhances apparent desensitization of recombinant GABAA receptor currents. Neuropharmacology. 35: 1233-41. PMID 9014138 DOI: 10.1016/S0028-3908(96)00053-6  0.478
1996 Kapur J, Macdonald RL. Cyclic AMP-dependent protein kinase enhances hippocampal dentate granule cell GABAA receptor currents. Journal of Neurophysiology. 76: 2626-34. PMID 8899633 DOI: 10.1152/Jn.1996.76.4.2626  0.63
1996 Kapur J, Macdonald RL. Pharmacological properties of gamma-aminobutyric acidA receptors from acutely dissociated rat dentate granule cells. Molecular Pharmacology. 50: 458-66. PMID 8794882  0.588
1996 Macdonald RL, Kelly KM. Antiepileptic drug mechanisms of action. Epilepsia. S2-12. PMID 8784210 DOI: 10.1111/j.1528-1157.1995.tb05996.x  0.469
1996 Greenfield LJ, Macdonald RL. Whole-cell and single-channel alpha1 beta1 gamma2S GABAA receptor currents elicited by a "multipuffer" drug application device. Pflugers Archiv : European Journal of Physiology. 432: 1080-90. PMID 8781204 DOI: 10.1007/s004240050238  0.394
1995 Macdonald RL. Ethanol, gamma-aminobutyrate type A receptors, and protein kinase C phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 92: 3633-5. PMID 7731956 DOI: 10.1073/PNAS.92.9.3633  0.316
1995 Rock DM, Macdonald RL. Polyamine regulation of N-methyl-D-aspartate receptor channels Annual Review of Pharmacology and Toxicology. 35: 463-482. PMID 7598503 DOI: 10.1146/ANNUREV.PA.35.040195.002335  0.395
1995 Hall K, Browning M, Dudek E, Macdonald R. Enhancement of high threshold calcium currents in rat primary afferent neurons by constitutively active protein kinase C The Journal of Neuroscience. 15: 6069-6076. DOI: 10.1523/JNEUROSCI.15-09-06069.1995  0.349
1994 Lin YF, Browning MD, Dudek EM, Macdonald RL. Protein kinase C enhances recombinant bovine alpha 1 beta 1 gamma 2L GABAA receptor whole-cell currents expressed in L929 fibroblasts. Neuron. 13: 1421-31. PMID 7993633 DOI: 10.1016/0896-6273(94)90427-8  0.479
1994 Macdonald RL, Olsen RW. GABAA receptor channels. Annual Review of Neuroscience. 17: 569-602. PMID 7516126 DOI: 10.1146/ANNUREV.NE.17.030194.003033  0.506
1994 Rogers CJ, Twyman RE, Macdonald RL. Benzodiazepine and beta-carboline regulation of single GABAA receptor channels of mouse spinal neurones in culture. The Journal of Physiology. 475: 69-82. PMID 7514665 DOI: 10.1113/jphysiol.1994.sp020050  0.487
1994 Macdonald RL, Kelly KM. Mechanisms of action of currently prescribed and newly developed antiepileptic drugs Epilepsia. 35. PMID 7513639 DOI: 10.1111/j.1528-1157.1994.tb05955.x  0.429
1994 Saxena N, Macdonald R. Assembly of GABAA receptor subunits: role of the delta subunit The Journal of Neuroscience. 14: 7077-7086. DOI: 10.1523/JNEUROSCI.14-11-07077.1994  0.432
1994 Moises H, Rusin K, Macdonald R. Mu- and kappa-opioid receptors selectively reduce the same transient components of high-threshold calcium current in rat dorsal root ganglion sensory neurons The Journal of Neuroscience. 14: 5903-5916. DOI: 10.1523/JNEUROSCI.14-10-05903.1994  0.365
1994 Moises H, Rusin K, Macdonald R. mu-Opioid receptor-mediated reduction of neuronal calcium current occurs via a G(o)-type GTP-binding protein The Journal of Neuroscience. 14: 3842-3851. DOI: 10.1523/JNEUROSCI.14-06-03842.1994  0.368
1993 Wiley JW, Gross RA, MacDonald RL. Agonists for neuropeptide Y receptor subtypes NPY-1 and NPY-2 have opposite actions on rat nodose neuron calcium currents. Journal of Neurophysiology. 70: 324-30. PMID 8395583 DOI: 10.1152/Jn.1993.70.1.324  0.506
1993 Macdonald RL, Kelly KM. Antiepileptic drug mechanisms of action Epilepsia. 34. PMID 7687957 DOI: 10.1111/j.1528-1157.1993.tb05918.x  0.313
1993 Angelotti TP, Uhler MD, Macdonald RL. Assembly of GABAA receptor subunits: Analysis of transient single-cell expression utilizing a fluorescent substrate/marker gene technique Journal of Neuroscience. 13: 1418-1428. PMID 7681869 DOI: 10.1523/Jneurosci.13-04-01418.1993  0.449
1993 Rock DM, Kelly KM, Macdonald RL. Gabapentin actions on ligand- and voltage-gated responses in cultured rodent neurons Epilepsy Research. 16: 89-98. PMID 7505742 DOI: 10.1016/0920-1211(93)90023-Z  0.457
1993 Twyman RE, Macdonald RL. Neurosteroid regulation of GABAA receptor single-channel kinetic properties of mouse spinal cord neurons in culture. The Journal of Physiology. 456: 215-45. PMID 1338096 DOI: 10.1113/jphysiol.1992.sp019334  0.506
1993 Angelotti TP, Tan F, Chahine KG, Macdonald RL. Molecular and electrophysiological characterization of a allelic variant of the rat alpha 6 GABAA receptor subunit. Brain Research. Molecular Brain Research. 16: 173-8. PMID 1281255 DOI: 10.1016/0169-328X(92)90209-T  0.415
1993 Angelotti T, Macdonald R. Assembly of GABAA receptor subunits: alpha 1 beta 1 and alpha 1 beta 1 gamma 2S subunits produce unique ion channels with dissimilar single- channel properties The Journal of Neuroscience. 13: 1429-1440. DOI: 10.1523/JNEUROSCI.13-04-01429.1993  0.379
1993 Macdonald RL, Angelotti TP. Native and Recombinant GABAA Receptor Channels Cellular Physiology and Biochemistry. 3: 352-373. DOI: 10.1159/000154698  0.383
1992 Twyman RE, Macdonald RL. Kinetic properties of the glycine receptor main- and sub-conductance states of mouse spinal cord neurones in culture. The Journal of Physiology. 435: 303-31. PMID 1722820 DOI: 10.1113/jphysiol.1991.sp018512  0.31
1992 Wiley JW, Gross RA, MacDonald RL. The peptide CGRP increases a high-threshold Ca2+ current in rat nodose neurones via a pertussis toxin-sensitive pathway. The Journal of Physiology. 455: 367-81. PMID 1336552 DOI: 10.1113/Jphysiol.1992.Sp019306  0.471
1992 Twyman RE, Green RM, MacDonald RL. Kinetics of open channel block by penicillin of single GABAA receptor channels from mouse spinal cord neurones in culture. The Journal of Physiology. 445: 97-127. PMID 1323672 DOI: 10.1113/jphysiol.1992.sp018914  0.481
1992 Rock DM, Macdonald RL. The polyamine diaminodecane (DA-10) produces a voltage-dependent flickery block of single NMDA receptor channels Neuroscience Letters. 144: 111-115. PMID 1279482 DOI: 10.1016/0304-3940(92)90728-P  0.377
1991 De Deyn PP, Macdonald RL. Guanidino compounds that are increased in cerebrospinal fluid and brain of uremic patients inhibit GABA and glycine responses on mouse neurons in cell culture. Annals of Neurology. 28: 627-33. PMID 2135950 DOI: 10.1002/ANA.410280505  0.405
1991 Kelly KM, Gross RA, Macdonald RL. Tetrahydroaminoacridine (THA) reduces voltage-dependent calcium currents in rat sensory neurons. Neuroscience Letters. 132: 247-50. PMID 1784428 DOI: 10.1016/0304-3940(91)90312-H  0.469
1991 De Deyn PP, Marescau B, Macdonald RL. Guanidino compounds that are increased in hyperargininemia inhibit GABA and glycine responses on mouse neurons in cell culture Epilepsy Research. 8: 134-141. PMID 1712285 DOI: 10.1016/0920-1211(91)90081-P  0.409
1991 Rock DM, McLean MJ, Macdonald RL, Catterall WA, Taylor CP. Ralitoline (CI-946) and CI-953 block sustained repetitive sodium action potentials in cultured mouse spinal cord neurons and displace batrachotoxinin A 20-alpha-benzoate binding in vitro. Epilepsy Research. 8: 197-203. PMID 1651226 DOI: 10.1016/0920-1211(91)90064-M  0.361
1991 Macdonald RL, Twyman RE. Biophysical properties and regulation of GABAA receptor channels Seminars in Neuroscience. 3: 219-230. DOI: 10.1016/1044-5765(91)90019-K  0.426
1990 MacDonald RL, Rogers CJ, Twyman RE. Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in culture. The Journal of Physiology. 417: 483-500. PMID 2482885 DOI: 10.1113/jphysiol.1989.sp017814  0.45
1990 Wiley JW, Gross RA, Lu YX, Macdonald RL. Neuropeptide Y reduces calcium current and inhibits acetylcholine release in nodose neurons via a pertussis toxin-sensitive mechanism. Journal of Neurophysiology. 63: 1499-507. PMID 2358888 DOI: 10.1152/Jn.1990.63.6.1499  0.494
1990 Gross RA, Uhler MD, Macdonald RL. The cyclic AMP-dependent protein kinase catalytic subunit selectively enhances calcium currents in rat nodose neurones. The Journal of Physiology. 429: 483-96. PMID 2177506 DOI: 10.1113/Jphysiol.1990.Sp018268  0.489
1990 Porter NM, Twyman RE, Uhler MD, Macdonald RL. Cyclic AMP-dependent protein kinase decreases GABAA receptor current in mouse spinal neurons Neuron. 5: 789-796. PMID 2176510 DOI: 10.1016/0896-6273(90)90338-G  0.461
1990 Kelly KM, Gross RA, Macdonald RL. Valproic acid selectively reduces the low-threshold (T) calcium current in rat nodose neurons. Neuroscience Letters. 116: 233-8. PMID 2175404 DOI: 10.1016/0304-3940(90)90416-7  0.477
1990 Moss SJ, Smart TG, Porter NM, Nayeem N, Devine J, Stephenson FA, Macdonald RL, Barnard EA. Cloned GABA receptors are maintained in a stable cell line: allosteric and channel properties. European Journal of Pharmacology. 189: 77-88. PMID 2171964 DOI: 10.1016/0922-4106(90)90232-M  0.517
1990 Twyman RE, Rogers CJ, Macdonald RL. Intraburst kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture. The Journal of Physiology. 423: 193-220. PMID 2167362 DOI: 10.1113/jphysiol.1990.sp018018  0.428
1990 Gross RA, Wiley JW, Ryan-Jastrow T, Macdonald RL. Regulation by GTP and its stable thiol derivatives of calcium current components in rat nodose ganglion neurons. Molecular Pharmacology. 37: 546-53. PMID 2157961  0.425
1990 Gross RA, Moises HC, Uhler MD, Macdonald RL. Dynorphin A and cAMP-dependent protein kinase independently regulate neuronal calcium currents. Proceedings of the National Academy of Sciences of the United States of America. 87: 7025-9. PMID 1976250 DOI: 10.1073/Pnas.87.18.7025  0.489
1990 Gross RA, Uhler MD, Macdonald RL. The reduction of neuronal calcium currents by ATP-gamma-S is mediated by a G protein and occurs independently of cyclic AMP-dependent protein kinase. Brain Research. 535: 214-20. PMID 1963568 DOI: 10.1016/0006-8993(90)91603-E  0.5
1990 Wiley J, Gross R, Macdonald R. Calcitonin gene-related peptide (CGRP) and protein kinase a (PKA) increase the N-type calcium current in rat vagal sensory (Nodose) neurons Gastroenterology. 99: 1236. DOI: 10.1016/0016-5085(90)90803-9  0.342
1989 Deyn PPD, Macdonald RL. Effects of antiepileptic drugs on GABA responses and on reduction of GABA responses by PTZ and DMCM on mouse neurons in cell culture. Epilepsia. 30: 17-25. PMID 2912714 DOI: 10.1111/J.1528-1157.1989.Tb05275.X  0.388
1989 Gross RA, MacDonald RL. Activators of protein kinase C selectively enhance inactivation of a calcium current component of cultured sensory neurons in a pertussis toxin-sensitive manner. Journal of Neurophysiology. 61: 1259-69. PMID 2746325 DOI: 10.1152/Jn.1989.61.6.1259  0.481
1989 Gross RA, Macdonald RL, Ryan-Jastrow T. 2-Chloroadenosine reduces the N calcium current of cultured mouse sensory neurones in a pertussis toxin-sensitive manner. The Journal of Physiology. 411: 585-95. PMID 2614735 DOI: 10.1113/Jphysiol.1989.Sp017592  0.477
1989 Rock DM, Macdonald RL, Taylor CP. Blockade of sustained repetitive action potentials in cultured spinal cord neurons by zonisamide (AD 810, CI 912), a novel anticonvulsant. Epilepsy Research. 3: 138-43. PMID 2565229 DOI: 10.1016/0920-1211(89)90041-7  0.392
1989 Macdonald RL. Antiepileptic drug actions. Epilepsia. S19-28; discussion S. PMID 2550216 DOI: 10.1111/j.1528-1157.1989.tb05810.x  0.475
1989 Gross RA, Macdonald RL. Cyclic AMP selectively reduces the N-type calcium current component of mouse sensory neurons in culture by enhancing inactivation. Journal of Neurophysiology. 61: 97-105. PMID 2537387 DOI: 10.1152/Jn.1989.61.1.97  0.467
1989 Macdonald RL, Rogers CJ, Twyman RE. Kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture. The Journal of Physiology. 410: 479-99. PMID 2477526 DOI: 10.1113/jphysiol.1989.sp017545  0.413
1989 Twyman RE, Rogers CJ, Macdonald RL. Differential regulation of gamma-aminobutyric acid receptor channels by diazepam and phenobarbital. Annals of Neurology. 25: 213-20. PMID 2471436 DOI: 10.1002/ANA.410250302  0.505
1989 Twyman RE, Rogers CJ, Macdonald RL. Pentobarbital and picrotoxin have reciprocal actions on single GABAA receptor channels. Neuroscience Letters. 96: 89-95. PMID 2467232 DOI: 10.1016/0304-3940(89)90248-6  0.501
1988 De Deyn PP, Marescau B, Macdonald RL. Effects of α-keto-δ-guanidinovaleric acid on inhibitory amino acid responses on mouse neurons in cell culture Brain Research. 449: 54-60. PMID 3395858 DOI: 10.1016/0006-8993(88)91023-2  0.41
1988 Macdonald RL. Anticonvulsant drug actions on neurons in cell culture Journal of Neural Transmission. 72: 173-183. PMID 3047314 DOI: 10.1007/Bf01243417  0.355
1988 Deyn PPD, Macdonald RL. Effects of non-sedative anxiolytic drugs on responses to GABA and on diazepam-induced enhancement of these responses on mouse neurones in cell culture. British Journal of Pharmacology. 95: 109-120. PMID 2905900 DOI: 10.1111/J.1476-5381.1988.Tb16554.X  0.444
1988 Gross RA, Macdonald RL. Differential actions of pentobarbitone on calcium current components of mouse sensory neurones in culture. The Journal of Physiology. 405: 187-203. PMID 2855640 DOI: 10.1113/Jphysiol.1988.Sp017328  0.478
1988 Gross RA, Macdonald RL. Reduction of the same calcium current component by A and C kinases: differential pertussis toxin sensitivity. Neuroscience Letters. 88: 50-6. PMID 2456492 DOI: 10.1016/0304-3940(88)90314-X  0.452
1988 Gross RA, Macdonald RL. Barbiturates and nifedipine have different and selective effects on calcium currents of mouse DRG neurons in culture: a possible basis for differing clinical actions. The 1987 S. Weir Mitchell award. Neurology. 38: 443-51. PMID 2450304 DOI: 10.1212/Wnl.38.3.443  0.48
1987 Werz MA, Macdonald RL. Dual actions of phorbol esters to decrease calcium and potassium conductances of mouse neurons. Neuroscience Letters. 78: 101-6. PMID 2441331 DOI: 10.1016/0304-3940(87)90569-6  0.322
1987 Gross RA, Macdonald RL. Dynorphin A selectively reduces a large transient (N-type) calcium current of mouse dorsal root ganglion neurons in cell culture. Proceedings of the National Academy of Sciences of the United States of America. 84: 5469-73. PMID 2440050 DOI: 10.1073/Pnas.84.15.5469  0.493
1987 Grega DS, Werz MA, Macdonald RL. Forskolin and phorbol esters reduce the same potassium conductance of mouse neurons in culture. Science (New York, N.Y.). 235: 345-8. PMID 2432663 DOI: 10.1126/SCIENCE.2432663  0.327
1987 Macdonald RL, Werz MA. Dynorphin A decreases voltage-dependent calcium conductance of mouse dorsal root ganglion neurones. The Journal of Physiology. 377: 237-49. PMID 2432242 DOI: 10.1113/jphysiol.1986.sp016184  0.35
1987 Werz M, Macdonald R. Phorbol esters: voltage-dependent effects on calcium-dependent action potentials of mouse central and peripheral neurons in cell culture The Journal of Neuroscience. 7: 1639-1647. DOI: 10.1523/JNEUROSCI.07-06-01639.1987  0.347
1987 Grega D, Macdonald R. Activators of adenylate cyclase and cyclic AMP prolong calcium- dependent action potentials of mouse sensory neurons in culture by reducing a voltage-dependent potassium conductance The Journal of Neuroscience. 7: 700-707. DOI: 10.1523/JNEUROSCI.07-03-00700.1987  0.323
1986 Macdonald RL, Weddle MG, Gross RA. Benzodiazepine, beta-carboline, and barbiturate actions on GABA responses. Advances in Biochemical Psychopharmacology. 41: 67-78. PMID 2874695  0.437
1986 MacDonald RL, Skerritt JH, Werz MA. Adenosine agonists reduce voltage-dependent calcium conductance of mouse sensory neurones in cell culture. The Journal of Physiology. 370: 75-90. PMID 2420981 DOI: 10.1113/jphysiol.1986.sp015923  0.372
1985 Werz MA, Macdonald RL. Dynorphin reduces voltage-dependent calcium conductance of mouse dorsal root ganglion neurons. Neuropeptides. 5: 253-6. PMID 6152324 DOI: 10.1016/0143-4179(84)90075-1  0.365
1985 Skerritt JH, Johnston GA, Chow SC, MacDonald RL, Prager RH, Ward AD. Differential modulation of gamma-aminobutyric acid receptors by caprolactam derivatives with central nervous system depressant or convulsant activity. Brain Research. 331: 225-33. PMID 2985202 DOI: 10.1016/0006-8993(85)91548-3  0.426
1984 Skerritt JH, Macdonald RL. Diazepam enhances the action but not the binding of the GABA analog, THIP. Brain Research. 297: 181-6. PMID 6722533 DOI: 10.1016/0006-8993(84)90557-2  0.415
1984 Skerritt JH, Werz MA, McLean MJ, Macdonald RL. Diazepam and its anomalous p-chloro-derivative Ro 5-4864: comparative effects on mouse neurons in cell culture. Brain Research. 310: 99-105. PMID 6478244 DOI: 10.1016/0006-8993(84)90013-1  0.332
1984 Werz MA, MacDonald RL. Opioid peptides selective for mu- and delta-opiate receptors reduce calcium-dependent action potential duration by increasing potassium conductance. Neuroscience Letters. 42: 173-8. PMID 6320066 DOI: 10.1016/0304-3940(83)90402-0  0.348
1984 Werz MA, Macdonald RL. Dynorphin reduces calcium-dependent action potential duration by decreasing voltage-dependent calcium conductance. Neuroscience Letters. 46: 185-90. PMID 6146120 DOI: 10.1016/0304-3940(84)90439-7  0.378
1984 Skerritt JH, Macdonald RL. Benzodiazepine Ro 15-1788: electrophysiological evidence for partial agonist activity. Neuroscience Letters. 43: 321-6. PMID 6143288 DOI: 10.1016/0304-3940(83)90208-2  0.434
1984 Skerritt JH, Macdonald RL. Benzodiazepine receptor ligand actions on GABA responses. Beta-carbolines, purines. European Journal of Pharmacology. 101: 135-41. PMID 6086358 DOI: 10.1016/0014-2999(84)90039-6  0.427
1984 Skerritt JH, Macdonald RL. Benzodiazepine receptor ligand actions on GABA responses. Benzodiazepines, CL 218872, zopiclone. European Journal of Pharmacology. 101: 127-34. PMID 6086357 DOI: 10.1016/0014-2999(84)90038-4  0.442
1984 Macdonald RL, Skerritt JH, McLean MJ. Anticonvulsant drug actions on GABA responses and sustained repetitive firing of neurons in cell culture Neuropharmacology. 23: 843-844. DOI: 10.1016/0028-3908(84)90275-2  0.44
1983 Nelson PG, Marshall KC, Pun RY, Christian CN, Sheriff WH, Macdonald RL, Neale EA. Synaptic interactions between mammalian central neurons in cell culture. II. Quantal Analysis of EPSPs. Journal of Neurophysiology. 49: 1442-58. PMID 6875632 DOI: 10.1152/Jn.1983.49.6.1442  0.515
1983 Macdonald RL, Pun RY, Neale EA, Nelson PG. Synaptic interactions between mammalian central neurons in cell culture. I. Reversal potential for excitatory postsynaptic potentials. Journal of Neurophysiology. 49: 1428-41. PMID 6875631 DOI: 10.1152/Jn.1983.49.6.1428  0.54
1983 Nowak LM, Macdonald RL. Muscarine-sensitive voltage-dependent potassium current in cultured murine spinal cord neurons. Neuroscience Letters. 35: 85-91. PMID 6843894 DOI: 10.1016/0304-3940(83)90531-1  0.717
1983 Nowak LM, Macdonald RL. Ionic mechanism of muscarinic cholinergic depolarization of mouse spinal cord neurons in cell culture. Journal of Neurophysiology. 49: 792-803. PMID 6834099 DOI: 10.1152/Jn.1983.49.3.792  0.752
1983 Bergey GK, MacDonald RL, Habig WH, Hardegree MC, Nelson PG. Tetanus toxin: convulsant action on mouse spinal cord neurons in culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 2310-23. PMID 6631482 DOI: 10.1523/Jneurosci.03-11-02310.1983  0.579
1983 Neale EA, Nelson PG, Macdonald RL, Christian CN, Bowers LM. Synaptic interactions between mammalian central neurons in cell culture. III. Morphophysiological correlates of quantal synaptic transmission. Journal of Neurophysiology. 49: 1459-68. PMID 6308178  0.461
1982 Neale EA, Moonen G, Macdonald RL, Nelson PG. Cerebellar macroneurons in microexplant cell culture: ultrastructural morphology. Neuroscience. 7: 1879-90. PMID 7133404 DOI: 10.1016/0306-4522(82)90004-5  0.527
1982 Werz MA, Macdonald RL. Opioid peptides decrease calcium-dependent action potential duration of mouse dorsal root ganglion neurons in cell culture. Brain Research. 239: 315-21. PMID 7093688 DOI: 10.1016/0006-8993(82)90859-9  0.351
1982 Werz MA, Macdonald RL. Opiate alkaloids antagonize postsynaptic glycine and GABA responses: correlation with convulsant action. Brain Research. 236: 107-19. PMID 7066678 DOI: 10.1016/0006-8993(82)90038-5  0.403
1982 Heyer EJ, Nowak LM, Macdonald RL. Membrane depolarization and prolongation of calcium-dependent action potentials of mouse neurons in cell culture by two convulsants: bicuculline and penicillin. Brain Research. 232: 41-56. PMID 7055710 DOI: 10.1016/0006-8993(82)90609-6  0.725
1982 Moonen G, Neale EA, Macdonald RL, Gibbs W, Nelson PG. Cerebellar macroneurons in microexplant cell culture. Methodology, basic electrophysiology, and morphology after horseradish peroxidase injection. Brain Research. 281: 59-73. PMID 6291726 DOI: 10.1016/0165-3806(82)90113-4  0.537
1982 Werz MA, Macdonald RL. Heterogeneous sensitivity of cultured dorsal root ganglion neurones to opioid peptides selective for mu- and delta-opiate receptors. Nature. 299: 730-3. PMID 6289131 DOI: 10.1038/299730A0  0.41
1982 Nowak LM, Young AB, Macdonald RL. GABA and bicuculline actions on mouse spinal cord and cortical neurons in cell culture. Brain Research. 244: 155-64. PMID 6288177 DOI: 10.1016/0006-8993(82)90913-1  0.761
1982 Frere RC, Macdonald RL, Young AB. GABA binding and bicuculline in spinal cord and cortical membranes from adult rat and from mouse neurons in cell culture. Brain Research. 244: 145-53. PMID 6288176 DOI: 10.1016/0006-8993(82)90912-X  0.367
1982 Heyer EJ, Macdonald RL. Barbiturate reduction of calcium-dependent action potentials: correlation with anesthetic action. Brain Research. 236: 157-71. PMID 6279233 DOI: 10.1016/0006-8993(82)90042-7  0.371
1982 Nowak LM, Macdonald RL. Substance P: ionic basis for depolarizing responses of mouse spinal cord neurons in cell culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 2: 1119-28. PMID 6180151 DOI: 10.1523/Jneurosci.02-08-01119.1982  0.703
1982 Macdonald RL, Moonen G, Neale EA, Nelson PG. Cerebellar macroneurons in microexplant cell culture. Postsynaptic amino acid pharmacology. Brain Research. 281: 75-88. PMID 6128065 DOI: 10.1016/0165-3806(82)90114-6  0.589
1981 Heyer EJ, MacDonald RL, Bergey GK, Nelson PG. Calcium-dependent action potentials in mouse spinal cord neurons in cell culture. Brain Research. 220: 408-15. PMID 7284766 DOI: 10.1016/0006-8993(81)91234-8  0.534
1981 Heyer EJ, Nowak LM, Macdonald RL. Bicuculline: a convulsant with synaptic and nonsynaptic actions. Neurology. 31: 1381-90. PMID 7198187 DOI: 10.1212/Wnl.31.11.1381  0.732
1981 Macdonald RL, Young AB. Pharmacology of GABA-mediated inhibition of spinal cord neurons in vivo and in primary dissociated cell culture. Molecular and Cellular Biochemistry. 38: 147-62. PMID 6270545 DOI: 10.1007/BF00235693  0.446
1981 Schulz DW, Macdonald RL. Barbiturate enhancement of GABA-mediated inhibition and activation of chloride ion conductance: correlation with anticonvulsant and anesthetic actions. Brain Research. 209: 177-88. PMID 6260300 DOI: 10.1016/0006-8993(81)91179-3  0.451
1981 Nowak LM, MacDonald RL. Substance P decreases a potassium conductance of spinal cord neurons in cell culture. Brain Research. 214: 416-23. PMID 6165445 DOI: 10.1016/0006-8993(81)91205-1  0.694
1981 Macdonald RL, Nowak LM. Substance P and somatostatin actions on spinal cord neurons in primary dissociated cell culture. Advances in Biochemical Psychopharmacology. 28: 159-73. PMID 6163331  0.679
1980 Neale EA, MacDonald RL, Nelson PG. An inhibitory spinal cord neuron. Jama. 244: 2555. PMID 7431596 DOI: 10.1001/jama.1980.03310220053031  0.501
1980 Macdonald RL, Nowak LM. Somatostatin actions in primary dissociated cell cultures of mammalian spinal cord neurons. International Journal of Neurology. 14: 221-32. PMID 6152909  0.662
1979 MacDonald RL, Barker JL. Enhancement of GABA-mediated postsynaptic inhibition in cultured mammalian spinal cord neurons: a common mode of anticonvulsant action. Brain Research. 167: 323-36. PMID 445132 DOI: 10.1016/0006-8993(79)90826-6  0.434
1979 Macdonald RL, Bergey GK. Valproic acid augments GABA-mediated postsynaptic inhibition in cultured mammalian neurons. Brain Research. 170: 558-62. PMID 380778 DOI: 10.1016/0006-8993(79)90975-2  0.392
1979 Macdonald RL, Barker JL. Anticonvulsant and anesthetic barbiturates: different postsynaptic actions in cultured mammalian neurons. Neurology. 29: 432-47. PMID 220560 DOI: 10.1212/WNL.29.4.432  0.45
1978 Nelson PG, Neale EA, Macdonald RL. Formation and modification of synapses in central nervous system cell cultures. Federation Proceedings. 37: 2010-5. PMID 565301  0.427
1978 Macdonald RL, Barker JL. Specific antagonism of GABA-mediated postsynaptic inhibition in cultured mammalian spinal cord neurons: a common mode of convulsant action. Neurology. 28: 325-30. PMID 565020 DOI: 10.1212/WNL.28.4.325  0.41
1978 Macdonald R, Barker JL. Benzodiazepines specifically modulate GABA-mediated postsynaptic inhibition in cultured mammalian neurones. Nature. 271: 563-4. PMID 563985 DOI: 10.1038/271563A0  0.477
1978 Neale EA, Macdonald RL, Nelson PG. Intracellular horseradish peroxidase injection for correlation of light and electron microscopic anatomy with synaptic physiology of cultured mouse spinal cord neurons. Brain Research. 152: 265-82. PMID 209872 DOI: 10.1016/0006-8993(78)90255-X  0.532
1978 Macdonald RL, Barker JL. Different actions of anticonvulsant and anesthetic barbiturates revealed by use of cultured mammalian neurons. Science (New York, N.Y.). 200: 775-7. PMID 205953 DOI: 10.1126/SCIENCE.205953  0.431
1978 Macdonald RL, Nelson PG. Specific-opiate-induced depression of transmitter release from dorsal root ganglion cells in culture. Science (New York, N.Y.). 199: 1449-51. PMID 204015 DOI: 10.1126/Science.204015  0.519
1977 Macdonald RL, Barker JL. Pentylenetetrazol and penicillin are selective antagonists of GABA-mediated post-synaptic inhibition in cultured mammalian neurones. Nature. 267: 720-1. PMID 195224 DOI: 10.1038/267720A0  0.415
1976 Cohen DH, MacDonald RL. Involvement of the avian hypothalamus in defensively conditioned heart rate change. The Journal of Comparative Neurology. 167: 465-80. PMID 1270630 DOI: 10.1002/Cne.901670405  0.392
1973 Macdonald RL, Cohen DH. Heart rate and blood pressure responses to electrical stimulation of the central nervous system in the pigeon (Columba livia). The Journal of Comparative Neurology. 150: 109-36. PMID 4579121 DOI: 10.1002/Cne.901500202  0.401
1971 Cohen DH, Macdonald RL. Some variables affecting orienting and conditioned heart-rate responses in the pigeon. Journal of Comparative and Physiological Psychology. 74: 123-33. PMID 5163697 DOI: 10.1037/H0030326  0.37
1970 Macdonald RL, Cohen DH. Cells of origin of sympathetic pre- and postganglionic cardioacceleratory fibers in the pigeon. The Journal of Comparative Neurology. 140: 343-58. PMID 5476888 DOI: 10.1002/Cne.901400307  0.396
1970 Cohen DH, Schnall AM, Macdonald RL, Pitts LH. Medullary cells of origin of vagal cardioinhibitory fibers in the pigeon. I. Anatomical studies of peripheral vagus nerve and the dorsal motor nucleus. The Journal of Comparative Neurology. 140: 299-320. PMID 5476886 DOI: 10.1002/Cne.901400305  0.397
Low-probability matches (unlikely to be authored by this person)
2004 Najm I, Ying Z, Babb T, Crino PB, Macdonald R, Mathern GW, Spreafico R. Mechanisms of epileptogenicity in cortical dysplasias. Neurology. 62: S9-13. PMID 15037672 DOI: 10.1212/01.Wnl.0000114506.49267.Bb  0.297
1982 Heyer EJ, Macdonald RL. Calcium- and sodium-dependent action potentials of mouse spinal cord and dorsal root ganglion neurons in cell culture. Journal of Neurophysiology. 47: 641-55. PMID 7069458 DOI: 10.1152/JN.1982.47.4.641  0.296
2001 Kelly KM, Kume A, Albin RL, Macdonald RL. Autoradiography of L-type and N-type calcium channels in aged rat hippocampus, entorhinal cortex, and neocortex. Neurobiology of Aging. 22: 17-23. PMID 11164272 DOI: 10.1016/S0197-4580(00)00178-0  0.295
1983 Macdonald RL, McLean MJ. Cellular bases of barbiturate and phenytoin anticonvulsant drug action. Epilepsia. S7-18. PMID 7140671 DOI: 10.1111/j.1528-1157.1982.tb06093.x  0.294
2017 Warner TA, Liu Z, Macdonald RL, Kang JQ. Heat induced temperature dysregulation and seizures in Dravet Syndrome/GEFS+ Gabrg2(+/Q390X) mice. Epilepsy Research. 134: 1-8. PMID 28505490 DOI: 10.1016/J.Eplepsyres.2017.04.020  0.292
2021 Hernandez CC, Tian X, Hu N, Shen W, Catron MA, Yang Y, Chen J, Jiang Y, Zhang Y, Macdonald RL. Dravet syndrome-associated mutations in , and define the genetic landscape of defects of GABA receptors. Brain Communications. 3: fcab033. PMID 34095830 DOI: 10.1093/braincomms/fcab033  0.289
2016 Delahanty RJ, Zhang Y, Bichell TJ, Shen W, Verdier K, Macdonald RL, Xu L, Boyd K, Williams J, Kang JQ. Beyond Epilepsy and Autism: Disruption of GABRB3 Causes Ocular Hypopigmentation. Cell Reports. 17: 3115-3124. PMID 28009282 DOI: 10.1016/J.Celrep.2016.11.067  0.283
1978 Barker JL, Neale JH, Smith TG, Macdonald RL. Opiate peptide modulation of amino acid responses suggests novel form of neuronal communication. Science (New York, N.Y.). 199: 1451-3. PMID 204016 DOI: 10.1126/SCIENCE.204016  0.283
2006 Macdonald RL, Kang JQ, Gallagher MJ, Feng HJ. GABAA Receptor Mutations Associated with Generalized Epilepsies1 Advances in Pharmacology. 54: 147-169. DOI: 10.1016/S1054-3589(06)54007-4  0.281
2010 Feng HJ, Kao C, Gallagher MJ, Jansen ED, Mahadevan-Jansen A, Konrad PE, Macdonald RL. Alteration of GABAergic neurotransmission by pulsed infrared laser stimulation. Journal of Neuroscience Methods. 192: 110-4. PMID 20654645 DOI: 10.1016/J.Jneumeth.2010.07.014  0.28
1999 Lowenstein DH, Bleck T, Macdonald RL. It's time to revise the definition of status epilepticus. Epilepsia. 40: 120-2. PMID 9924914 DOI: 10.1111/j.1528-1157.1999.tb02000.x  0.275
2014 Macdonald RL, Gallagher MJ. Properties and Regulation of GABAA and Glycine Receptor Channels Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00031-3  0.269
2018 Bailey DM, Catron MA, Kovtun O, Macdonald RL, Zhang Q, Rosenthal SJ. Single Quantum Dot Tracking Reveals Serotonin Transporter Diffusion Dynamics are Correlated with Cholesterol-Sensitive Threonine 276 Phosphorylation Status in Primary Midbrain Neurons. Acs Chemical Neuroscience. PMID 29787674 DOI: 10.1021/Acschemneuro.8B00214  0.243
1995 Pennell PB, Ogaily MS, Macdonald RL. Aplastic anemia in a patient receiving felbamate for complex partial seizures. Neurology. 45: 456-60. PMID 7898696 DOI: 10.1212/WNL.45.3.456  0.237
2018 Lin H, Hu N, Zhang Y, Wang Y, Macdonald RL. Whole exome sequencing reveals novel NOV and DCAF13 variants in a Chinese pedigree with familial cortical myoclonic tremor with epilepsy. Neuroscience Letters. PMID 30003937 DOI: 10.1016/j.neulet.2018.07.014  0.235
1990 Kanaan N, Kadish A, Jenkins J, Childs K, MacDonald R. Automated detection and analysis of monophasic action potentials in vivo Journal of Electrocardiology. 22: 127. PMID 2614291 DOI: 10.1016/S0022-0736(07)80111-7  0.235
1975 MacDonald RL, Hsu D, Mann JE, Sperelakis N. An analysis of the problem of K-+ accumulation in the intercalated disk clefts of cardiac muscle. Journal of Theoretical Biology. 51: 455-73. PMID 1142797 DOI: 10.1016/0022-5193(75)90074-0  0.234
2006 Leppik I, Löscher W, Macdonald R, Schmidt D. New Co-Editors-in-Chief for Epilepsy Research Epilepsy Research. 70: 1. DOI: 10.1016/j.eplepsyres.2006.05.007  0.226
1985 Macdonald R, McLean M. Anticonvulsant drug mechanisms of action Electroencephalography and Clinical Neurophysiology. 61: S16-S17. DOI: 10.1016/0013-4694(85)90099-9  0.222
1992 MacDonald RL, Twyman RE. Kinetic properties and regulation of GABAA receptor channels. Ion Channels. 3: 315-43. PMID 1384760 DOI: 10.1007/978-1-4615-3328-3_10  0.214
1975 Sperelakis N, Macdonald RL. Ratio of transverse to longitudinal resistivities of isolated cardiac muscle fiber bundles. Journal of Electrocardiology. 7: 301-14. PMID 4462694 DOI: 10.1016/S0022-0736(74)80061-0  0.208
1999 King AP, Hall KE, Macdonald RL. kappa- and mu-Opioid inhibition of N-type calcium currents is attenuated by 4beta-phorbol 12-myristate 13-acetate and protein kinase C in rat dorsal root ganglion neurons. The Journal of Pharmacology and Experimental Therapeutics. 289: 312-20. PMID 10087019  0.202
1974 Macdonald RL, Mann JE, Sperelakis N. Derivation of general equations describing tracer diffusion in any two-compartment tissue with application to ionic diffusion in cylindrical muscle bundles. Journal of Theoretical Biology. 45: 107-30. PMID 4836883 DOI: 10.1016/0022-5193(74)90046-0  0.202
2007 Xie A, Aihara Y, Bouryi VA, Nikitina E, Jahromi BS, Zhang ZD, Takahashi M, Macdonald RL. Novel mechanism of endothelin-1-induced vasospasm after subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 1692-701. PMID 17392694 DOI: 10.1038/Sj.Jcbfm.9600471  0.188
1999 Bleck TP, Jensen FE, Mizrahi EM, Macdonald RL. Panel discussion: Discussion and questions from the audience Epilepsia. 40: S64-S66. DOI: 10.1111/j.1528-1157.1999.tb00881.x  0.182
1993 Eismann E, Bönigk W, Kaupp B, Macdonald RL, Angelotti TP, Paulmichl M, Gschwentner M, Wöll E, Schmarda A, Ritter M, Kanin G, Ellemunter H, Waitz W, Deetjen P, Carroll TP, et al. Subject Index, Vol. 3, 1993 Cellular Physiology and Biochemistry. 3: 401-402. DOI: 10.1159/000154702  0.179
2016 Janve VS, Hernandez CC, Verdier KM, Hu N, Macdonald RL. Reply. Annals of Neurology. PMID 27270493 DOI: 10.1002/Ana.24701  0.161
2007 Nikitina E, Zhang ZD, Kawashima A, Jahromi BS, Bouryi VA, Takahashi M, Xie A, Macdonald RL. Voltage-dependent calcium channels of dog basilar artery. The Journal of Physiology. 580: 523-41. PMID 17185332 DOI: 10.1113/Jphysiol.2006.126128  0.161
1993 Eismann E, Bönigk W, Kaupp B, Macdonald RL, Angelotti TP, Paulmichl M, Gschwentner M, Wöll E, Schmarda A, Ritter M, Kanin G, Ellemunter H, Waitz W, Deetjen P, Carroll TP, et al. Contents, Vol. 3, 1993 Cellular Physiology and Biochemistry. 3. DOI: 10.1159/000154687  0.16
2008 Jahromi BS, Aihara Y, Ai J, Zhang ZD, Nikitina E, Macdonald RL. Voltage-gated K+ channel dysfunction in myocytes from a dog model of subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 797-811. PMID 17987046 DOI: 10.1038/Sj.Jcbfm.9600577  0.155
2006 MacDonald RL, Kakarieka A, Mayer SA, Pasqualin A, Ruefenacht D, Schmiedek P, Kassell NF. Prevention of Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage with Clazosentan, an Endothelin Receptor Antagonist 801. Neurosurgery. 59: 453. PMID 28180682 DOI: 10.1227/01.NEU.0000309851.15854.A6  0.154
2010 Nikitina E, Kawashima A, Takahashi M, Zhang ZD, Shang X, Ai J, Macdonald RL. Alteration in voltage-dependent calcium channels in dog basilar artery after subarachnoid hemorrhage. Laboratory investigation. Journal of Neurosurgery. 113: 870-80. PMID 20225918 DOI: 10.3171/2010.2.JNS091038  0.151
2022 Mukherjee S, Cassini TA, Hu N, Yang T, Li B, Shen W, Moth CW, Rinker DC, Sheehan JH, Cogan JD, Newman JH, Hamid R, Macdonald RL, Roden DM, Meiler J, et al. Personalized structural biology reveals the molecular mechanisms underlying heterogeneous epileptic phenotypes caused by KCNC2 variants. Hgg Advances. 3: 100131. PMID 36035247 DOI: 10.1016/j.xhgg.2022.100131  0.151
2004 Aihara Y, Jahromi BS, Yassari R, Nikitina E, Agbaje-Williams M, Macdonald RL. Molecular profile of vascular ion channels after experimental subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 75-83. PMID 14688619 DOI: 10.1097/01.Wcb.0000095803.98378.D8  0.148
2008 Jahromi BS, Aihara Y, Ai J, Zhang ZD, Weyer G, Nikitina E, Yassari R, Houamed KM, Macdonald RL. Preserved BK channel function in vasospastic myocytes from a dog model of subarachnoid hemorrhage. Journal of Vascular Research. 45: 402-15. PMID 18401179 DOI: 10.1159/000124864  0.144
2008 Jahromi BS, Aihara Y, Ai J, Zhang ZD, Weyer G, Nikitina E, Yassari R, Houamed KM, Macdonald RL. Temporal profile of potassium channel dysfunction in cerebrovascular smooth muscle after experimental subarachnoid haemorrhage. Neuroscience Letters. 440: 81-6. PMID 18547725 DOI: 10.1016/J.Neulet.2008.05.015  0.14
2002 Macdonald RL, Zhang ZD, Ono S, Komuro T. Up-regulation of parathyroid hormone receptor in cerebral arteries after subarachnoid hemorrhage in monkeys. Neurosurgery. 50: 1083-91; discussion . PMID 11950412 DOI: 10.1097/00006123-200205000-00025  0.138
2014 Bell JD, Thomas TC, Lass E, Ai J, Wan H, Lifshitz J, Baker AJ, Macdonald RL. Platelet-mediated changes to neuronal glutamate receptor expression at sites of microthrombosis following experimental subarachnoid hemorrhage. Journal of Neurosurgery. 121: 1424-31. PMID 24745710 DOI: 10.3171/2014.3.Jns132130  0.132
2006 Weyer GW, Jahromi BS, Aihara Y, Agbaje-Williams M, Nikitina E, Zhang ZD, Macdonald RL. Expression and function of inwardly rectifying potassium channels after experimental subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 382-91. PMID 16079788 DOI: 10.1038/Sj.Jcbfm.9600193  0.124
2012 Zoerle T, Ilodigwe DC, Wan H, Lakovic K, Sabri M, Ai J, Macdonald RL. Pharmacologic reduction of angiographic vasospasm in experimental subarachnoid hemorrhage: systematic review and meta-analysis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 1645-58. PMID 22534672 DOI: 10.1038/jcbfm.2012.57  0.121
2004 Takahashi M, Macdonald RL. Vascular aspects of neuroprotection. Neurological Research. 26: 862-9. PMID 15727270 DOI: 10.1179/016164104X3815  0.119
2019 Carlson AP, Hänggi D, Macdonald RL, Shuttleworth CW. Nimodipine Reappraised: An Old Drug With a Future. Current Neuropharmacology. PMID 31560289 DOI: 10.2174/1570159X17666190927113021  0.117
2006 MacDonald RL. Evidence-based treatment of subarachnoid hemorrhage: current status and future possibilities. Clinical Neurosurgery. 53: 257-66. PMID 17380760  0.112
2014 Eisa-Beygi S, Wen XY, Macdonald RL. A call for rigorous study of statins in resolution of cerebral cavernous malformation pathology. Stroke; a Journal of Cerebral Circulation. 45: 1859-61. PMID 24803598 DOI: 10.1161/Strokeaha.114.005132  0.111
2005 Alexander JJ, Jacob A, Bao L, Macdonald RL, Quigg RJ. Complement-dependent apoptosis and inflammatory gene changes in murine lupus cerebritis. Journal of Immunology (Baltimore, Md. : 1950). 175: 8312-9. PMID 16339572 DOI: 10.4049/jimmunol.175.12.8312  0.103
2014 Macdonald RL, Gallagher MJ. The Genetic Epilepsies Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease: Fifth Edition. 973-998. DOI: 10.1016/B978-0-12-410529-4.00084-X  0.103
2008 Macdonald RL. Clazosentan: an endothelin receptor antagonist for treatment of vasospasm after subarachnoid hemorrhage. Expert Opinion On Investigational Drugs. 17: 1761-7. PMID 18922111 DOI: 10.1517/13543784.17.11.1761  0.101
2013 Ibrahim GM, Fallah A, Macdonald RL. Clinical, laboratory, and radiographic predictors of the occurrence of seizures following aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery. 119: 347-52. PMID 23581590 DOI: 10.3171/2013.3.JNS122097  0.101
2013 Sabri M, Ai J, Lakovic K, Macdonald RL. Mechanisms of microthrombosis and microcirculatory constriction after experimental subarachnoid hemorrhage. Acta Neurochirurgica. Supplement. 115: 185-92. PMID 22890667 DOI: 10.1007/978-3-7091-1192-5_35  0.1
2008 Sabri M, Kawashima A, Ai J, Macdonald RL. Neuronal and astrocytic apoptosis after subarachnoid hemorrhage: a possible cause for poor prognosis. Brain Research. 1238: 163-71. PMID 18786513 DOI: 10.1016/j.brainres.2008.08.031  0.097
2014 Macdonald RL. Seizures after craniectomy: an under-recognised complication? Journal of Neurology, Neurosurgery, and Psychiatry. 85: 714. PMID 23962620 DOI: 10.1136/jnnp-2013-306102  0.097
2015 Yagi K, Lidington D, Wan H, Fares JC, Meissner A, Sumiyoshi M, Ai J, Foltz WD, Nedospasov SA, Offermanns S, Nagahiro S, Macdonald RL, Bolz SS. Therapeutically Targeting Tumor Necrosis Factor-α/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage. Stroke; a Journal of Cerebral Circulation. 46: 2260-70. PMID 26138121 DOI: 10.1161/Strokeaha.114.006365  0.097
2010 Tariq A, Ai J, Chen G, Sabri M, Jeon H, Shang X, Macdonald RL. Loss of long-term potentiation in the hippocampus after experimental subarachnoid hemorrhage in rats. Neuroscience. 165: 418-26. PMID 19854243 DOI: 10.1016/j.neuroscience.2009.10.040  0.097
2014 Han SM, Wan H, Kudo G, Foltz WD, Vines DC, Green DE, Zoerle T, Tariq A, Brathwaite S, D'Abbondanza J, Ai J, Macdonald RL. Molecular alterations in the hippocampus after experimental subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 108-17. PMID 24064494 DOI: 10.1038/Jcbfm.2013.170  0.096
2010 Jeon H, Ai J, Sabri M, Tariq A, Macdonald RL. Learning deficits after experimental subarachnoid hemorrhage in rats. Neuroscience. 169: 1805-14. PMID 20600651 DOI: 10.1016/j.neuroscience.2010.06.039  0.089
2001 Komuro T, Borsody MK, Ono S, Marton LS, Weir BK, Zhang ZD, Paik E, Macdonald RL. The vasorelaxation of cerebral arteries by carbon monoxide. Experimental Biology and Medicine (Maywood, N.J.). 226: 860-5. PMID 11568310 DOI: 10.1177/153537020122600909  0.088
2014 Brathwaite S, Macdonald RL. Current management of delayed cerebral ischemia: update from results of recent clinical trials. Translational Stroke Research. 5: 207-26. PMID 24338266 DOI: 10.1007/s12975-013-0316-8  0.085
2014 Macdonald RL. Delayed neurological deterioration after subarachnoid haemorrhage. Nature Reviews. Neurology. 10: 44-58. PMID 24323051 DOI: 10.1038/nrneurol.2013.246  0.085
2011 Sabri M, Ai J, Macdonald RL. Dissociation of vasospasm and secondary effects of experimental subarachnoid hemorrhage by clazosentan. Stroke; a Journal of Cerebral Circulation. 42: 1454-60. PMID 21454820 DOI: 10.1161/STROKEAHA.110.604728  0.084
2011 Sabri M, Ai J, Marsden PA, Macdonald RL. Simvastatin re-couples dysfunctional endothelial nitric oxide synthase in experimental subarachnoid hemorrhage. Plos One. 6: e17062. PMID 21373645 DOI: 10.1371/journal.pone.0017062  0.084
2011 Macdonald RL, Higashida RT, Keller E, Mayer SA, Molyneux A, Raabe A, Vajkoczy P, Wanke I, Bach D, Frey A, Marr A, Roux S, Kassell N. Clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid haemorrhage undergoing surgical clipping: a randomised, double-blind, placebo-controlled phase 3 trial (CONSCIOUS-2). The Lancet. Neurology. 10: 618-25. PMID 21640651 DOI: 10.1016/S1474-4422(11)70108-9  0.082
2008 Aihara Y, Jahromi BS, Yassari R, Takahashi M, Macdonald RL. Induction of housekeeping gene expression after subarachnoid hemorrhage in dogs. Journal of Neuroscience Methods. 172: 1-7. PMID 18490059 DOI: 10.1016/J.Jneumeth.2008.03.020  0.082
2012 Sabri M, Ai J, Lakovic K, D'abbondanza J, Ilodigwe D, Macdonald RL. Mechanisms of microthrombi formation after experimental subarachnoid hemorrhage. Neuroscience. 224: 26-37. PMID 22902542 DOI: 10.1016/j.neuroscience.2012.08.002  0.082
2006 Weyer GW, Nolan CP, Macdonald RL. Evidence-based cerebral vasospasm management. Neurosurgical Focus. 21: E8. PMID 17029347 DOI: 10.3171/FOC.2006.21.3.8  0.08
2011 Chen G, Tariq A, Ai J, Sabri M, Jeon HJ, Tang EJ, Lakovic K, Wan H, Macdonald RL. Different effects of clazosentan on consequences of subarachnoid hemorrhage in rats. Brain Research. 1392: 132-9. PMID 21466789 DOI: 10.1016/j.brainres.2011.03.068  0.079
2004 Yassari R, Sayama T, Jahromi BS, Aihara Y, Stoodley M, Macdonald RL. Angiographic, hemodynamic and histological characterization of an arteriovenous fistula in rats. Acta Neurochirurgica. 146: 495-504. PMID 15118887 DOI: 10.1007/S00701-004-0248-X  0.078
2001 Jahromi BS, Komuro T, Macdonald RL, Marton LS, Weir BK. Phosphatidylcholine peroxidized by hemoglobin increases intracellular calcium in dog basilar artery smooth muscle cells. Acta Neurochirurgica. Supplement. 77: 45-7. PMID 11563307 DOI: 10.1007/978-3-7091-6232-3_11  0.078
2009 Sabri M, Jeon H, Ai J, Tariq A, Shang X, Chen G, Macdonald RL. Anterior circulation mouse model of subarachnoid hemorrhage. Brain Research. 1295: 179-85. PMID 19686712 DOI: 10.1016/j.brainres.2009.08.021  0.076
2014 Eisa-Beygi S, Ekker M, Moon TW, Macdonald RL, Wen XY. Developmental processes regulated by the 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway: highlights from animal studies. Reproductive Toxicology (Elmsford, N.Y.). 46: 115-20. PMID 24732207 DOI: 10.1016/J.Reprotox.2014.04.001  0.074
2011 Tang J, Ai J, Macdonald RL. Developing a model of chronic subdural hematoma. Acta Neurochirurgica. Supplement. 111: 25-9. PMID 21725727 DOI: 10.1007/978-3-7091-0693-8_5  0.074
2008 Macdonald RL, Kassell NF, Mayer S, Ruefenacht D, Schmiedek P, Weidauer S, Frey A, Roux S, Pasqualin A. Clazosentan to overcome neurological ischemia and infarction occurring after subarachnoid hemorrhage (CONSCIOUS-1): randomized, double-blind, placebo-controlled phase 2 dose-finding trial. Stroke; a Journal of Cerebral Circulation. 39: 3015-21. PMID 18688013 DOI: 10.1161/STROKEAHA.108.519942  0.074
2007 Macdonald RL, Pluta RM, Zhang JH. Cerebral vasospasm after subarachnoid hemorrhage: the emerging revolution. Nature Clinical Practice. Neurology. 3: 256-63. PMID 17479073 DOI: 10.1038/ncpneuro0490  0.073
2001 Macdonald RL, Weir BK, Marton LS, Zhang ZD, Sajdak M, Johns LM, Kowalczuk A, Borsody M. Role of adenosine 5'-triphosphate in vasospasm after subarachnoid hemorrhage: human investigations. Neurosurgery. 48: 854-62; discussion 8. PMID 11322446 DOI: 10.1097/00006123-200104000-00033  0.072
2011 Sabri M, Ai J, Macdonald RL. Nitric oxide related pathophysiological changes following subarachnoid haemorrhage. Acta Neurochirurgica. Supplement. 110: 105-9. PMID 21116924 DOI: 10.1007/978-3-7091-0353-1_19  0.067
2002 Macdonald RL, Zhang ZD, Curry D, Elas M, Aihara Y, Halpern H, Jahromi BS, Johns L. Intracisternal sodium nitroprusside fails to prevent vasospasm in nonhuman primates. Neurosurgery. 51: 761-8; discussion 76. PMID 12188956 DOI: 10.1097/00006123-200209000-00027  0.067
2006 Macdonald RL, Zhang ZD, Takahashi M, Nikitina E, Young J, Xie A, Larkin L. Calcium sensitivity of vasospastic basilar artery after experimental subarachnoid hemorrhage. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2329-36. PMID 16399868 DOI: 10.1152/ajpheart.00911.2005  0.067
2014 Eisa-Beygi S, Macdonald RL, Wen XY. Regulatory pathways affecting vascular stabilization via VE-cadherin dynamics: insights from zebrafish (Danio rerio). Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 1430-3. PMID 25027310 DOI: 10.1038/Jcbfm.2014.128  0.066
2014 Tso MK, Macdonald RL. Subarachnoid hemorrhage: a review of experimental studies on the microcirculation and the neurovascular unit. Translational Stroke Research. 5: 174-89. PMID 24510780 DOI: 10.1007/s12975-014-0323-4  0.065
2015 Maher M, Churchill NW, de Oliveira Manoel AL, Graham SJ, Macdonald RL, Schweizer TA. Altered Resting-State Connectivity within Executive Networks after Aneurysmal Subarachnoid Hemorrhage. Plos One. 10: e0130483. PMID 26172281 DOI: 10.1371/Journal.Pone.0130483  0.063
2014 Congleton J, Shen M, MacDonald R, Malavasi F, Yen A. Phosphorylation of c-Cbl and p85 PI3K driven by all-trans retinoic acid and CD38 depends on Lyn kinase activity. Cellular Signalling. 26: 1589-97. PMID 24686085 DOI: 10.1016/J.Cellsig.2014.03.021  0.063
2001 Lin G, Macdonald RL, Marton LS, Kowalczuk A, Solenski NJ, Weir BK. Hemoglobin increases endothelin-1 in endothelial cells by decreasing nitric oxide. Biochemical and Biophysical Research Communications. 280: 824-30. PMID 11162595 DOI: 10.1006/bbrc.2000.4167  0.061
2009 Jeon H, Ai J, Sabri M, Tariq A, Shang X, Chen G, Macdonald RL. Neurological and neurobehavioral assessment of experimental subarachnoid hemorrhage. Bmc Neuroscience. 10: 103. PMID 19706182 DOI: 10.1186/1471-2202-10-103  0.06
1997 Macdonald RL, Weir B, Zhang J, Marton LS, Sajdak M, Johns LM. Adenosine triphosphate and hemoglobin in vasospastic monkeys. Neurosurgical Focus. 3: e3. PMID 15104409 DOI: 10.3171/FOC.1997.3.4.6  0.06
2015 Martinez JL, Macdonald RL. Surgical Strategies for Acutely Ruptured Arteriovenous Malformations. Frontiers of Neurology and Neuroscience. 37: 166-81. PMID 26587641 DOI: 10.1159/000437121  0.059
2013 Macdonald RL, Higashida RT, Keller E, Mayer SA, Molyneux A, Raabe A, Vajkoczy P, Wanke I, Bach D, Frey A, Marr A, Roux S, Kassell N. Randomised trial of clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid hemorrhage undergoing surgical clipping (CONSCIOUS-2). Acta Neurochirurgica. Supplement. 115: 27-31. PMID 22890639 DOI: 10.1007/978-3-7091-1192-5_7  0.058
2012 Macdonald RL. Endothelin antagonists in subarachnoid hemorrhage: what next? Critical Care (London, England). 16: 171. PMID 23146320 DOI: 10.1186/cc11822  0.058
2015 D'Abbondanza JA, Ai J, Lass E, Wan H, Brathwaite S, Tso MK, Lee C, Marsden PA, Macdonald RL. Robust effects of genetic background on responses to subarachnoid hemorrhage in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661216 DOI: 10.1177/0271678X15612489  0.057
2013 Zoerle T, Ilodigwe D, Wan H, Lakovic K, Sabri M, Ai J, Macdonald RL. Pharmacologic reduction of angiographic vasospasm in experimental subarachnoid hemorrhage: systematic review. Acta Neurochirurgica. Supplement. 115: 247-51. PMID 22890676 DOI: 10.1007/978-3-7091-1192-5_44  0.057
2010 Macdonald RL, Higashida RT, Keller E, Mayer SA, Molyneux A, Raabe A, Vajkoczy P, Wanke I, Frey A, Marr A, Roux S, Kassell NF. Preventing vasospasm improves outcome after aneurysmal subarachnoid hemorrhage: rationale and design of CONSCIOUS-2 and CONSCIOUS-3 trials. Neurocritical Care. 13: 416-24. PMID 20838933 DOI: 10.1007/s12028-010-9433-3  0.057
2015 Hemphill JC, Greenberg SM, Anderson CS, Becker K, Bendok BR, Cushman M, Fung GL, Goldstein JN, Macdonald RL, Mitchell PH, Scott PA, Selim MH, Woo D. Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke; a Journal of Cerebral Circulation. 46: 2032-60. PMID 26022637 DOI: 10.1161/STR.0000000000000069  0.057
2013 Witiw CD, Citow JS, Ginsberg HJ, Spears J, Perrin RG, Cusimano MD, Macdonald RL. A novel device to simplify intraoperative radiographic visualization of the cervical spine by producing transient caudal shoulder displacement: a 2-center case series of 80 patients. Journal of Neurosurgery. Spine. 19: 697-700. PMID 24093467 DOI: 10.3171/2013.9.SPINE11998  0.056
2001 Ono S, Komuro T, Macdonald RL. Adenovirus-mediated heme oxygenase-1 gene transfection prevents hemoglobin-induced contraction of rat basilar artery. Acta Neurochirurgica. Supplement. 77: 93-6. PMID 11563317 DOI: 10.1007/978-3-7091-6232-3_20  0.055
2014 Shrimp JH, Hu J, Dong M, Wang BS, MacDonald R, Jiang H, Hao Q, Yen A, Lin H. Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe. Journal of the American Chemical Society. 136: 5656-63. PMID 24660829 DOI: 10.1021/Ja411046J  0.054
2013 Summerfield TC, Crawford TS, Young RD, Chua JP, Macdonald RL, Sherman LA, Eaton-Rye JJ. Environmental pH affects photoautotrophic growth of Synechocystis sp. PCC 6803 strains carrying mutations in the lumenal proteins of PSII. Plant & Cell Physiology. 54: 859-74. PMID 23444302 DOI: 10.1093/Pcp/Pct036  0.053
2014 MacDonald RL, Chen HYH, Palik BP, Prepas EE. Influence of harvesting on understory vegetation along a boreal riparian-upland gradient Forest Ecology and Management. 312: 138-147. DOI: 10.1016/J.Foreco.2013.10.011  0.053
2012 Strong AJ, Macdonald RL. Cortical spreading ischemia in the absence of proximal vasospasm after aneurysmal subarachnoid hemorrhage: evidence for a dual mechanism of delayed cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 201-2. PMID 22146191 DOI: 10.1038/jcbfm.2011.170  0.052
2014 Macdonald RL. Vasospasm: My first 25 years—what worked? what didn't? what next? Acta Neurochirurgica, Supplementum. 120: 1-10. PMID 25366591 DOI: 10.1007/978-3-319-04981-6_1  0.052
2005 Yarnitsky D, Lorian A, Shalev A, Zhang ZD, Takahashi M, Agbaje-Williams M, Macdonald RL. Reversal of cerebral vasospasm by sphenopalatine ganglion stimulation in a dog model of subarachnoid hemorrhage. Surgical Neurology. 64: 5-11; discussion 11. PMID 15993169 DOI: 10.1016/j.surneu.2004.09.029  0.051
2014 Etminan N, Beseoglu K, Barrow DL, Bederson J, Brown RD, Connolly ES, Derdeyn CP, Hänggi D, Hasan D, Juvela S, Kasuya H, Kirkpatrick PJ, Knuckey N, Koivisto T, Lanzino G, ... ... Macdonald RL, et al. Multidisciplinary consensus on assessment of unruptured intracranial aneurysms: proposal of an international research group. Stroke; a Journal of Cerebral Circulation. 45: 1523-30. PMID 24668202 DOI: 10.1161/Strokeaha.114.004519  0.051
2006 Zhang ZD, Macdonald RL. Contribution of the remodeling response to cerebral vasospasm. Neurological Research. 28: 713-20. PMID 17164034 DOI: 10.1179/016164106X151990  0.051
2013 Jaja BN, Saposnik G, Nisenbaum R, Schweizer TA, Reddy D, Thorpe KE, Macdonald RL. Effect of socioeconomic status on inpatient mortality and use of postacute care after subarachnoid hemorrhage. Stroke; a Journal of Cerebral Circulation. 44: 2842-7. PMID 23899917 DOI: 10.1161/Strokeaha.113.001368  0.049
2001 Citow JS, Rini B, Wollmann R, Macdonald RL. Isolated, primary extranodal Hodgkin's disease of the spine: case report. Neurosurgery. 49: 453-6; discussion 45. PMID 11504124 DOI: 10.1097/00006123-200108000-00037  0.048
2012 MacDonald RL. Reversal of transcranial Doppler vasospasm with sildenafil Surgical Neurology International. 3. DOI: 10.4103/2152-7806.92164  0.048
2003 Aihara Y, Jahromi BS, Yassari R, Sayama T, Macdonald RL. Effects of a nitric oxide donor on and correlation of changes in cyclic nucleotide levels with experimental vasospasm. Neurosurgery. 52: 661-7; discussion 66. PMID 12590692 DOI: 10.1227/01.Neu.0000048188.88980.86  0.048
2022 Lincoln JD, MacDonald RL, Little B, Syme A, Thomas CG. Comparison of anatomically informed class solution template trajectories with patient-specific trajectories for stereotactic radiosurgery and radiotherapy. Journal of Applied Clinical Medical Physics. e13765. PMID 36052983 DOI: 10.1002/acm2.13765  0.048
2012 Ibrahim GM, Macdonald RL. Electrocardiographic changes predict angiographic vasospasm after aneurysmal subarachnoid hemorrhage. Stroke; a Journal of Cerebral Circulation. 43: 2102-7. PMID 22678087 DOI: 10.1161/STROKEAHA.112.658153  0.047
2013 Sabri M, Ai J, Lass E, D'abbondanza J, Macdonald RL. Genetic elimination of eNOS reduces secondary complications of experimental subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1008-14. PMID 23549379 DOI: 10.1038/jcbfm.2013.49  0.047
2021 Falisse JB, Macdonald R, Molony T, Nugent P. Why have so many African leaders died of COVID-19? Bmj Global Health. 6. PMID 34001520 DOI: 10.1136/bmjgh-2021-005587  0.047
2015 Macdonald RL. Subarachnoid Hemorrhage and Loss of Consciousness. Jama Neurology. 1-2. PMID 26551437 DOI: 10.1001/jamaneurol.2015.3485  0.046
2014 de Oliveira Manoel AL, Mansur A, Murphy A, Turkel-Parrella D, Macdonald M, Macdonald RL, Montanera W, Marotta TR, Bharatha A, Effendi K, Schweizer TA. Aneurysmal subarachnoid haemorrhage from a neuroimaging perspective. Critical Care (London, England). 18: 557. PMID 25673429 DOI: 10.1186/S13054-014-0557-2  0.046
2013 Fukuda H, Munoz D, Macdonald RL. Spontaneous thalamic hemorrhage from a lateral posterior choroidal artery aneurysm. World Neurosurgery. 80: 900.e1-6. PMID 23396071 DOI: 10.1016/J.Wneu.2013.02.006  0.046
2014 Ibrahim GM, Morgan BR, Macdonald RL. Patient phenotypes associated with outcomes after aneurysmal subarachnoid hemorrhage: a principal component analysis. Stroke; a Journal of Cerebral Circulation. 45: 670-6. PMID 24425125 DOI: 10.1161/STROKEAHA.113.003078  0.046
2006 Nolan CP, Macdonald RL. Can angiographic vasospasm be used as a surrogate marker in evaluating therapeutic interventions for cerebral vasospasm? Neurosurgical Focus. 21: E1. PMID 17029333 DOI: 10.3171/FOC.2006.21.3.1  0.046
2013 Sheldon S, Macdonald RL, Cusimano M, Spears J, Schweizer TA. Long-term consequences of subarachnoid hemorrhage: examining working memory. Journal of the Neurological Sciences. 332: 145-7. PMID 23871092 DOI: 10.1016/J.Jns.2013.06.021  0.045
2015 Guha D, Coyne S, Macdonald RL. Timing of the resumption of antithrombotic agents following surgical evacuation of chronic subdural hematomas: a retrospective cohort study. Journal of Neurosurgery. 1-10. PMID 26361283 DOI: 10.3171/2015.2.JNS141889  0.045
2013 Tso MK, Macdonald RL. Acute microvascular changes after subarachnoid hemorrhage and transient global cerebral ischemia. Stroke Research and Treatment. 2013: 425281. PMID 23589781 DOI: 10.1155/2013/425281  0.044
2002 Ono S, Komuro T, Macdonald RL. Heme oxygenase-1 gene therapy for prevention of vasospasm in rats. Journal of Neurosurgery. 96: 1094-102. PMID 12066912 DOI: 10.3171/jns.2002.96.6.1094  0.044
2010 Macdonald RL. Concerns regarding the recent report of simvastatin inhibition of microthrombosis after subarachnoid hemorrhage in rats. Annals of Clinical and Laboratory Science. 40: 182-3; author reply . PMID 20421632  0.044
2014 Macdonald RL. Reversing rat poison-is faster better? World Neurosurgery. 81: 43-5. PMID 23500125 DOI: 10.1016/j.wneu.2013.03.013  0.043
2015 Ibrahim GM, Macdonald RL. The network topology of aneurysmal subarachnoid haemorrhage. Journal of Neurology, Neurosurgery, and Psychiatry. 86: 895-901. PMID 25280913 DOI: 10.1136/jnnp-2014-308992  0.043
2013 Rotondo F, Kovacs K, Macdonald RL, Prud'homme GJ, Latta E, Munoz D. Non-small cell bronchial carcinoma metastasizing into a prolactin-producing pituitary adenoma. International Journal of Surgical Pathology. 21: 68-71. PMID 22689615 DOI: 10.1177/1066896912449478  0.043
2012 Hill MD, Martin RH, Mikulis D, Wong JH, Silver FL, Terbrugge KG, Milot G, Clark WM, Macdonald RL, Kelly ME, Boulton M, Fleetwood I, McDougall C, Gunnarsson T, Chow M, et al. Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial. The Lancet. Neurology. 11: 942-50. PMID 23051991 DOI: 10.1016/S1474-4422(12)70225-9  0.042
2012 Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke; a Journal of Cerebral Circulation. 43: 683-90. PMID 22267829 DOI: 10.1161/Strokeaha.111.633958  0.042
2014 Jaja BN, Attalla D, Macdonald RL, Schweizer TA, Cusimano MD, Etminan N, Hanggi D, Hasan D, Johnston SC, Le Roux P, Lo B, Louffat-Olivares A, Mayer S, Molyneux A, Noble A, et al. The Subarachnoid Hemorrhage International Trialists (SAHIT) Repository: advancing clinical research in subarachnoid hemorrhage. Neurocritical Care. 21: 551-9. PMID 24865271 DOI: 10.1007/S12028-014-9990-Y  0.042
2012 Macdonald RL, Leung M, Tice T. Intracranial drug delivery for subarachnoid hemorrhage. Therapeutic Delivery. 3: 91-103. PMID 22833935 DOI: 10.4155/tde.11.124  0.041
2007 Hansen-Schwartz J, Vajkoczy P, Macdonald RL, Pluta RM, Zhang JH. Cerebral vasospasm: looking beyond vasoconstriction. Trends in Pharmacological Sciences. 28: 252-6. PMID 17466386 DOI: 10.1016/j.tips.2007.04.002  0.041
2014 Wan H, AlHarbi BM, Macdonald RL. Mechanisms, treatment and prevention of cellular injury and death from delayed events after aneurysmal subarachnoid hemorrhage. Expert Opinion On Pharmacotherapy. 15: 231-43. PMID 24283706 DOI: 10.1517/14656566.2014.865724  0.041
2013 Jaja BN, Cusimano MD, Etminan N, Hanggi D, Hasan D, Ilodigwe D, Lantigua H, Le Roux P, Lo B, Louffat-Olivares A, Mayer S, Molyneux A, Quinn A, Schweizer TA, Schenk T, ... ... Macdonald RL, et al. Clinical prediction models for aneurysmal subarachnoid hemorrhage: a systematic review. Neurocritical Care. 18: 143-53. PMID 23138544 DOI: 10.1007/S12028-012-9792-Z  0.041
2018 Macdonald RL. Management of Intracranial Hemorrhage in the Anticoagulated Patient. Neurosurgery Clinics of North America. 29: 605-613. PMID 30223973 DOI: 10.1016/j.nec.2018.06.013  0.041
2014 Kapadia A, Schweizer TA, Spears J, Cusimano M, Macdonald RL. Nonaneurysmal perimesencephalic subarachnoid hemorrhage: diagnosis, pathophysiology, clinical characteristics, and long-term outcome. World Neurosurgery. 82: 1131-43. PMID 25003696 DOI: 10.1016/J.Wneu.2014.07.006  0.041
2010 Sabri M, Macdonald RL. Statins: a potential therapeutic addition to treatment for aneurysmal subarachnoid hemorrhage? World Neurosurgery. 73: 646-53. PMID 20934152 DOI: 10.1016/j.wneu.2010.03.032  0.04
2013 Tam AK, Kapadia A, Ilodigwe D, Li Z, Schweizer TA, Macdonald RL. Impact of global cerebral atrophy on clinical outcome after subarachnoid hemorrhage. Journal of Neurosurgery. 119: 198-206. PMID 23662822 DOI: 10.3171/2013.3.Jns121950  0.04
2008 Pearl JD, Macdonald RL. Vasospasm after aneurysmal subarachnoid hemorrhage: need for further study. Acta Neurochirurgica. Supplement. 105: 207-10. PMID 19066110 DOI: 10.1007/978-3-211-09469-3_39  0.04
1970 Sperelakis N, Mayer G, Macdonald R. Velocity of propagation in vertebrate cardiac muscles as functions of tonicity and [K+]. The American Journal of Physiology. 219: 952-63. PMID 5459497 DOI: 10.1152/AJPLEGACY.1970.219.4.952  0.04
2011 George SJ, Wan S, Hu J, MacDonald R, Johnson JL, Baker AH. Sustained reduction of vein graft neointima formation by ex vivo TIMP-3 gene therapy. Circulation. 124: S135-42. PMID 21911803 DOI: 10.1161/CIRCULATIONAHA.110.012732  0.04
2013 Witiw CD, Ibrahim GM, Fallah A, Macdonald RL. Early predictors of prolonged stay in a critical care unit following aneurysmal subarachnoid hemorrhage. Neurocritical Care. 18: 291-7. PMID 23371849 DOI: 10.1007/s12028-013-9815-4  0.039
2007 Grosenick D, Kummrow A, Macdonald R, Schlag PM, Rinneberg H. Evaluation of higher-order time-domain perturbation theory of photon diffusion on breast-equivalent phantoms and optical mammograms. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 76: 061908. PMID 18233870 DOI: 10.1103/PHYSREVE.76.061908  0.039
2012 Cook DJ, Kan S, Ai J, Kasuya H, Macdonald RL. Cisternal sustained release dihydropyridines for subarachnoid hemorrhage. Current Neurovascular Research. 9: 139-48. PMID 22475399 DOI: 10.2174/156720212800410894  0.039
2021 Wulczyn E, Steiner DF, Moran M, Plass M, Reihs R, Tan F, Flament-Auvigne I, Brown T, Regitnig P, Chen PC, Hegde N, Sadhwani A, MacDonald R, Ayalew B, Corrado GS, et al. Interpretable survival prediction for colorectal cancer using deep learning. Npj Digital Medicine. 4: 71. PMID 33875798 DOI: 10.1038/s41746-021-00427-2  0.039
2001 Macdonald RL. Pathophysiology and molecular genetics of vasospasm. Acta Neurochirurgica. Supplement. 77: 7-11. PMID 11563312 DOI: 10.1007/978-3-7091-6232-3_2  0.039
2011 Crowley RW, Medel R, Dumont AS, Ilodigwe D, Kassell NF, Mayer SA, Ruefenacht D, Schmiedek P, Weidauer S, Pasqualin A, Macdonald RL. Angiographic vasospasm is strongly correlated with cerebral infarction after subarachnoid hemorrhage. Stroke; a Journal of Cerebral Circulation. 42: 919-23. PMID 21350201 DOI: 10.1161/STROKEAHA.110.597005  0.039
2014 Etminan N, Buchholz BA, Dreier R, Bruckner P, Torner JC, Steiger HJ, Hänggi D, Macdonald RL. Cerebral aneurysms: formation, progression, and developmental chronology. Translational Stroke Research. 5: 167-73. PMID 24323717 DOI: 10.1007/S12975-013-0294-X  0.039
2011 Vergouwen MD, Ilodigwe D, Macdonald RL. Cerebral infarction after subarachnoid hemorrhage contributes to poor outcome by vasospasm-dependent and -independent effects. Stroke; a Journal of Cerebral Circulation. 42: 924-9. PMID 21311062 DOI: 10.1161/STROKEAHA.110.597914  0.038
2008 Neuhaus F, Widom J, MacDonald R, Jardetzky T, Radhakrishnan I. Program review: Challenges and opportunities for training the next generation of biophysicists: Perspectives of the directors of the Molecular Biophysics Training Program at Northwestern University Biopolymers. 89: 253-255. PMID 18293401 DOI: 10.1002/Bip.20929  0.038
2012 Macdonald RL, Higashida RT, Keller E, Mayer SA, Molyneux A, Raabe A, Vajkoczy P, Wanke I, Bach D, Frey A, Nowbakht P, Roux S, Kassell N. Randomized trial of clazosentan in patients with aneurysmal subarachnoid hemorrhage undergoing endovascular coiling. Stroke; a Journal of Cerebral Circulation. 43: 1463-9. PMID 22403047 DOI: 10.1161/STROKEAHA.111.648980  0.038
2015 Tso MK, Ibrahim GM, Macdonald RL. Predictors of Shunt-Dependent Hydrocephalus Following Aneurysmal Subarachnoid Hemorrhage. World Neurosurgery. PMID 26428322 DOI: 10.1016/j.wneu.2015.09.056  0.038
2012 Ibrahim GM, Weidauer S, Vatter H, Raabe A, Macdonald RL. Attributing hypodensities on CT to angiographic vasospasm is not sensitive and unreliable. Stroke; a Journal of Cerebral Circulation. 43: 109-12. PMID 21998061 DOI: 10.1161/STROKEAHA.111.632745  0.037
2023 Maroufi SF, Farahbakhsh F, Macdonald RL, Khoshnevisan A. Risk factors for recurrence of chronic subdural hematoma after surgical evacuation: a systematic review and meta-analysis. Neurosurgical Review. 46: 270. PMID 37843688 DOI: 10.1007/s10143-023-02175-1  0.037
2015 Attia MS, Lass E, Macdonald RL. Nitric oxide synthases: Three pieces to the puzzle? Acta Neurochirurgica, Supplementum. 120: 131-135. PMID 25366612 DOI: 10.1007/978-3-319-04981-6_22  0.037
2015 Jaja BN, Lingsma H, Schweizer TA, Thorpe KE, Steyerberg EW, Macdonald RL. Prognostic value of premorbid hypertension and neurological status in aneurysmal subarachnoid hemorrhage: pooled analyses of individual patient data in the SAHIT repository. Journal of Neurosurgery. 122: 644-52. PMID 25554825 DOI: 10.3171/2014.10.Jns132694  0.037
2013 Jaja BN, Saposnik G, Nisenbaum R, Lo BW, Schweizer TA, Thorpe KE, Macdonald RL. Racial/ethnic differences in inpatient mortality and use of institutional postacute care following subarachnoid hemorrhage. Journal of Neurosurgery. 119: 1627-32. PMID 24015781 DOI: 10.3171/2013.7.Jns13544  0.037
2014 Kassardjian CD, Macdonald RL, Munoz DG. Hemangioblastomas in the elderly: epidemiology and clinical characteristics. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 21: 1205-8. PMID 24629394 DOI: 10.1016/J.Jocn.2013.10.023  0.036
2019 Nagpal K, Foote D, Liu Y, Chen PC, Wulczyn E, Tan F, Olson N, Smith JL, Mohtashamian A, Wren JH, Corrado GS, MacDonald R, Peng LH, Amin MB, Evans AJ, et al. Development and validation of a deep learning algorithm for improving Gleason scoring of prostate cancer. Npj Digital Medicine. 2: 48. PMID 31304394 DOI: 10.1038/S41746-019-0112-2  0.036
2015 Macdonald RL, Chen HYH, Bartels SF, Palik BJ, Prepas EE. Compositional stability of boreal understorey vegetation after overstorey harvesting across a riparian ecotone Journal of Vegetation Science. 26: 733-741. DOI: 10.1111/Jvs.12272  0.036
2012 Schweizer TA, Al-Khindi T, Macdonald RL. Mini-Mental State Examination versus Montreal Cognitive Assessment: rapid assessment tools for cognitive and functional outcome after aneurysmal subarachnoid hemorrhage. Journal of the Neurological Sciences. 316: 137-40. PMID 22280947 DOI: 10.1016/J.Jns.2012.01.003  0.036
2015 Hänggi D, Etminan N, Macdonald RL, Steiger HJ, Mayer SA, Aldrich F, Diringer MN, Hoh BL, Mocco J, Strange P, Faleck HJ, Miller M. NEWTON: Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage. Neurocritical Care. PMID 25678453 DOI: 10.1007/s12028-015-0112-2  0.036
2013 Alahmadi H, Cusimano MD, Woo K, Mohammed AA, Goguen J, Smyth HS, Macdonald RL, Muller PJ, Horvath E, Kovacs K. Impact of technique on cushing disease outcome using strict remission criteria. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 40: 334-41. PMID 23603168 DOI: 10.1017/S031716710001427X  0.036
2014 Reddy D, Fallah A, Petropoulos JA, Farrokhyar F, Macdonald RL, Jichici D. Prophylactic magnesium sulfate for aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis. Neurocritical Care. 21: 356-64. PMID 24619389 DOI: 10.1007/s12028-014-9964-0  0.036
2011 Vergouwen MD, Etminan N, Ilodigwe D, Macdonald RL. Lower incidence of cerebral infarction correlates with improved functional outcome after aneurysmal subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1545-53. PMID 21505477 DOI: 10.1038/jcbfm.2011.56  0.036
2007 Macdonald RL. Lumbar drainage after subarachnoid hemorrhage: does it reduce vasospasm and delayed hydrocephalus? Neurocritical Care. 7: 1-2. PMID 17657651 DOI: 10.1007/s12028-007-0046-4  0.036
2010 Morgenstern LB, Hemphill JC, Anderson C, Becker K, Broderick JP, Connolly ES, Greenberg SM, Huang JN, MacDonald RL, Messé SR, Mitchell PH, Selim M, Tamargo RJ. Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke; a Journal of Cerebral Circulation. 41: 2108-29. PMID 20651276 DOI: 10.1161/Str.0B013E3181Ec611B  0.035
2004 Macdonald RL, Curry DJ, Aihara Y, Zhang ZD, Jahromi BS, Yassari R. Magnesium and experimental vasospasm. Journal of Neurosurgery. 100: 106-10. PMID 14743919 DOI: 10.3171/Jns.2004.100.1.0106  0.035
2002 Hamilton A, Rabbat M, Jain P, Belkind N, Huang SL, Nagaraj A, Klegerman M, Macdonald R, McPherson DD. A physiologic flow chamber model to define intravascular ultrasound enhancement of fibrin using echogenic liposomes. Investigative Radiology. 37: 215-21. PMID 11923644  0.035
2007 Toth G, Rubeiz H, Macdonald RL. Polytetrafluoroethylene-induced granuloma and brainstem cyst after microvascular decompression for trigeminal neuralgia: case report. Neurosurgery. 61: E875-7; discussion E. PMID 17986923 DOI: 10.1227/01.NEU.0000298919.62742.EB  0.035
2012 Macdonald RL, Hunsche E, Schüler R, Wlodarczyk J, Mayer SA. Quality of life and healthcare resource use associated with angiographic vasospasm after aneurysmal subarachnoid hemorrhage. Stroke; a Journal of Cerebral Circulation. 43: 1082-8. PMID 22328549 DOI: 10.1161/STROKEAHA.111.634071  0.035
2015 Etminan N, Macdonald RL, Davis C, Burton K, Steiger HJ, Hänggi D. Intrathecal application of the nimodipine slow-release microparticle system eg-1962 for prevention of delayed cerebral ischemia and improvement of outcome after aneurysmal subarachnoid hemorrhage. Acta Neurochirurgica. Supplement. 120: 281-6. PMID 25366637 DOI: 10.1007/978-3-319-04981-6_47  0.035
2004 Reilly C, Amidei C, Tolentino J, Jahromi BS, Macdonald RL. Clot volume and clearance rate as independent predictors of vasospasm after aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery. 101: 255-61. PMID 15309916 DOI: 10.3171/Jns.2004.101.2.0255  0.035
2013 Mathieu E, Gupta N, Macdonald RL, Ai J, Yücel YH. In vivo imaging of lymphatic drainage of cerebrospinal fluid in mouse. Fluids and Barriers of the Cns. 10: 35. PMID 24360130 DOI: 10.1186/2045-8118-10-35  0.034
2018 Steiner DF, MacDonald R, Liu Y, Truszkowski P, Hipp JD, Gammage C, Thng F, Peng L, Stumpe MC. Impact of Deep Learning Assistance on the Histopathologic Review of Lymph Nodes for Metastatic Breast Cancer. The American Journal of Surgical Pathology. PMID 30312179 DOI: 10.1097/Pas.0000000000001151  0.034
2013 Macdonald RL, Cusimano MD, Etminan N, Hanggi D, Hasan D, Ilodigwe D, Jaja B, Lantigua H, Le Roux P, Lo B, Louffat-Olivares A, Mayer S, Molyneux A, Quinn A, Schweizer TA, et al. Subarachnoid Hemorrhage International Trialists data repository (SAHIT). World Neurosurgery. 79: 418-22. PMID 23295631 DOI: 10.1016/J.Wneu.2013.01.006  0.033
2013 Ibrahim GM, Macdonald RL. The effects of fluid balance and colloid administration on outcomes in patients with aneurysmal subarachnoid hemorrhage: a propensity score-matched analysis. Neurocritical Care. 19: 140-9. PMID 23715669 DOI: 10.1007/s12028-013-9860-z  0.033
2001 Zhang ZD, Yamini B, Komuro T, Ono S, Johns L, Marton LS, Weir B, Macdonald RL. Vasospasm in monkeys resolves because of loss of and encasement of subarachnoid blood clot. Stroke; a Journal of Cerebral Circulation. 32: 1868-74. PMID 11486119 DOI: 10.1161/01.Str.32.8.1868  0.033
2015 Etminan N, Brown RD, Beseoglu K, Juvela S, Raymond J, Morita A, Torner JC, Derdeyn CP, Raabe A, Mocco J, Korja M, Abdulazim A, Amin-Hanjani S, Al-Shahi Salman R, Barrow DL, ... ... Macdonald RL, et al. The unruptured intracranial aneurysm treatment score: A multidisciplinary consensus. Neurology. PMID 26276380 DOI: 10.1212/Wnl.0000000000001891  0.033
2013 Sabri M, Lass E, Macdonald RL. Early brain injury: a common mechanism in subarachnoid hemorrhage and global cerebral ischemia. Stroke Research and Treatment. 2013: 394036. PMID 23533958 DOI: 10.1155/2013/394036  0.033
2011 Takahashi M, Zhang ZD, Macdonald RL. Sphenopalatine ganglion stimulation for vasospasm after experimental subarachnoid hemorrhage. Journal of Neurosurgery. 114: 1104-9. PMID 20597600 DOI: 10.3171/2010.6.JNS091525  0.032
2014 Al-Khindi T, Macdonald RL, Schweizer TA. Decision-making deficits persist after aneurysmal subarachnoid hemorrhage. Neuropsychology. 28: 68-74. PMID 24040927 DOI: 10.1037/Neu0000003  0.032
2012 Kapadia AN, Naik NP, MacDonald RL, Schweizer TA. Cognitive and mood profile of sturge-weber syndrome affecting the thalamus Canadian Journal of Neurological Sciences. 39: 402-404. PMID 22666901 DOI: 10.1017/S031716710002223X  0.032
2014 Etminan N, Dreier R, Buchholz BA, Beseoglu K, Bruckner P, Matzenauer C, Torner JC, Brown RD, Steiger HJ, Hänggi D, Macdonald RL. Age of collagen in intracranial saccular aneurysms. Stroke; a Journal of Cerebral Circulation. 45: 1757-63. PMID 24781080 DOI: 10.1161/Strokeaha.114.005461  0.031
2007 Young JB, Jahromi BS, Zhang ZD, Macdonald RL. A novel device for in vitro isometric tension recordings of cylindrical artery segments. Medical Engineering & Physics. 29: 169-74. PMID 16529973 DOI: 10.1016/J.Medengphy.2006.02.003  0.031
2005 Rosen DS, Macdonald RL. Subarachnoid hemorrhage grading scales: a systematic review. Neurocritical Care. 2: 110-8. PMID 16159052 DOI: 10.1385/NCC:2:2:110  0.031
2013 Macdonald RL. Whether subarachnoid hemorrhage depends on the weather? World Neurosurgery. 79: 64-5. PMID 23103265 DOI: 10.1016/j.wneu.2012.10.028  0.031
2016 de Oliveira Manoel AL, Goffi A, Marotta TR, Schweizer TA, Abrahamson S, Macdonald RL. The critical care management of poor-grade subarachnoid haemorrhage. Critical Care (London, England). 20: 21. PMID 26801901 DOI: 10.1186/S13054-016-1193-9  0.031
2014 Guha D, Ibrahim GM, Kertzer JD, Macdonald RL. National socioeconomic indicators are associated with outcomes after aneurysmal subarachnoid hemorrhage: a hierarchical mixed-effects analysis. Journal of Neurosurgery. 121: 1039-47. PMID 25127417 DOI: 10.3171/2014.7.JNS132141  0.03
2011 Macdonald RL. Optimal antiepileptic drug use for patients with subarachnoid hemorrhage. World Neurosurgery. 75: 211-3. PMID 21492716 DOI: 10.1016/j.wneu.2010.10.050  0.03
2014 Lakovic K, Ai J, D'Abbondanza J, Tariq A, Sabri M, Alarfaj AK, Vasdev P, Macdonald RL. Bilirubin and its oxidation products damage brain white matter. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 1837-47. PMID 25160671 DOI: 10.1038/jcbfm.2014.154  0.03
2013 Macdonald RL. History and definition of delayed cerebral ischemia. Acta Neurochirurgica. Supplement. 115: 3-7. PMID 22890634 DOI: 10.1007/978-3-7091-1192-5_2  0.03
2010 Al-Khindi T, Macdonald RL, Schweizer TA. Cognitive and functional outcome after aneurysmal subarachnoid hemorrhage. Stroke; a Journal of Cerebral Circulation. 41: e519-36. PMID 20595669 DOI: 10.1161/Strokeaha.110.581975  0.03
2023 Picetti E, Bouzat P, Bader MK, Citerio G, Helbok R, Horn J, Macdonald RL, McCredie V, Meyfroidt G, Righy C, Robba C, Sharma D, Smith WS, Suarez JI, Udy A, et al. A Survey on Monitoring and Management of Cerebral Vasospasm and Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: The Mantra Study. Journal of Neurosurgical Anesthesiology. PMID 37254166 DOI: 10.1097/ANA.0000000000000923  0.03
2019 Chen PC, Gadepalli K, MacDonald R, Liu Y, Kadowaki S, Nagpal K, Kohlberger T, Dean J, Corrado GS, Hipp JD, Mermel CH, Stumpe MC. An augmented reality microscope with real-time artificial intelligence integration for cancer diagnosis. Nature Medicine. PMID 31406351 DOI: 10.1038/S41591-019-0539-7  0.03
2011 Zhang XW, Maunder GH, Giessmann S, MacDonald R, Ferguson MJ, Bond AH, Rogers RD, Sella A, Takats J. Stable heteroleptic complexes of divalent lanthanides with bulky pyrazolylborate ligands--iodides, hydrocarbyls and triethylborohydrides. Dalton Transactions (Cambridge, England : 2003). 40: 195-210. PMID 21072414 DOI: 10.1039/C0Dt00162G  0.029
2010 Schweizer TA, Macdonald RL. Brain hemorrhage: assessing outcome after subarachnoid hemorrhage. Nature Reviews. Neurology. 6: 427-8. PMID 20689567 DOI: 10.1038/Nrneurol.2010.94  0.029
2012 Hasan D, Hashimoto T, Kung D, Macdonald RL, Winn HR, Heistad D. Upregulation of cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase-1 (mPGES-1) in wall of ruptured human cerebral aneurysms: preliminary results. Stroke; a Journal of Cerebral Circulation. 43: 1964-7. PMID 22588264 DOI: 10.1161/Strokeaha.112.655829  0.029
2004 Macdonald RL, Marton LS, Andrus PK, Hall ED, Johns L, Sajdak M. Time course of production of hydroxyl free radical after subarachnoid hemorrhage in dogs. Life Sciences. 75: 979-89. PMID 15193958 DOI: 10.1016/J.Lfs.2004.02.010  0.029
2022 Rautalin I, Juvela S, Martini ML, Macdonald RL, Korja M. Risk Factors for Delayed Cerebral Ischemia in Good-Grade Patients With Aneurysmal Subarachnoid Hemorrhage. Journal of the American Heart Association. e027453. PMID 36444866 DOI: 10.1161/JAHA.122.027453  0.029
2010 Vergouwen MD, Vermeulen M, van Gijn J, Rinkel GJ, Wijdicks EF, Muizelaar JP, Mendelow AD, Juvela S, Yonas H, Terbrugge KG, Macdonald RL, Diringer MN, Broderick JP, Dreier JP, Roos YB. Definition of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage as an outcome event in clinical trials and observational studies: proposal of a multidisciplinary research group. Stroke; a Journal of Cerebral Circulation. 41: 2391-5. PMID 20798370 DOI: 10.1161/Strokeaha.110.589275  0.028
2012 MacDonald RL, Burke JM, Chen HYH, Prepas EE. Relationship between aboveground biomass and percent cover of ground vegetation in Canadian Boreal Plain riparian forests Forest Science. 58: 47-53. DOI: 10.5849/Forsci.10-129  0.028
2012 Sheldon S, Macdonald RL, Schweizer TA. Free recall memory performance after aneurysmal subarachnoid hemorrhage. Journal of the International Neuropsychological Society : Jins. 18: 334-42. PMID 22325677 DOI: 10.1017/S1355617711001780  0.028
2013 Tam AK, Ilodigwe D, Li Z, Schweizer TA, Macdonald RL. Global cerebral atrophy after subarachnoid hemorrhage: a possible marker of acute brain injury and assessment of its impact on outcome. Acta Neurochirurgica. Supplement. 115: 17-21. PMID 22890637 DOI: 10.1007/978-3-7091-1192-5_5  0.028
2002 Hamilton A, Huang SL, Warnick D, Stein A, Rabbat M, Madhav T, Kane B, Nagaraj A, Klegerman M, MacDonald R, McPherson D. Left ventricular thrombus enhancement after intravenous injection of echogenic immunoliposomes: studies in a new experimental model. Circulation. 105: 2772-8. PMID 12057993 DOI: 10.1161/01.CIR.0000017500.61563.80  0.028
2014 Germans MR, Macdonald RL. Is a sylvian fissure hematoma caused by leaking vessels? World Neurosurgery. 82: e689-91. PMID 24076213 DOI: 10.1016/j.wneu.2013.09.047  0.028
2003 Macdonald RL, Amidei C, Baron J, Weir B, Brown F, Erickson RK, Hekmatpanah J, Frim D. Randomized, pilot study of intermittent pneumatic compression devices plus dalteparin versus intermittent pneumatic compression devices plus heparin for prevention of venous thromboembolism in patients undergoing craniotomy. Surgical Neurology. 59: 363-72; discussion 3. PMID 12765806 DOI: 10.1016/S0090-3019(03)00111-3  0.028
2009 Pluta RM, Hansen-Schwartz J, Dreier J, Vajkoczy P, Macdonald RL, Nishizawa S, Kasuya H, Wellman G, Keller E, Zauner A, Dorsch N, Clark J, Ono S, Kiris T, Leroux P, et al. Cerebral vasospasm following subarachnoid hemorrhage: time for a new world of thought. Neurological Research. 31: 151-8. PMID 19298755 DOI: 10.1179/174313209X393564  0.027
2013 Ilodigwe D, Murray GD, Kassell NF, Torner J, Kerr RS, Molyneux AJ, Macdonald RL. Sliding dichotomy compared with fixed dichotomization of ordinal outcome scales in subarachnoid hemorrhage trials. Journal of Neurosurgery. 118: 3-12. PMID 23039145 DOI: 10.3171/2012.9.Jns111383  0.027
2007 Aust T, Herod J, Macdonald R, Gazvani R. Infertility after fertility-preserving surgery for cervical carcinoma: the next challenge for reproductive medicine? Human Fertility (Cambridge, England). 10: 21-4. PMID 17454205 DOI: 10.1080/14647270600905342  0.026
2009 Jang YG, Ilodigwe D, Macdonald RL. Metaanalysis of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage. Neurocritical Care. 10: 141-7. PMID 18810661 DOI: 10.1007/s12028-008-9147-y  0.026
2012 Fine B, Singh N, Aviv R, Macdonald RL. Decisions: does a patient with a thunderclap headache need a lumbar puncture? Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 184: 555-6. PMID 22392938 DOI: 10.1503/cmaj.110517  0.026
2015 Murphy A, de Oliveira Manoel AL, Burgers K, Kouzmina E, Lee T, Macdonald RL, Bharatha A. Early CT perfusion changes and blood-brain barrier permeability after aneurysmal subarachnoid hemorrhage. Neuroradiology. PMID 25868518 DOI: 10.1007/s00234-015-1529-1  0.025
2015 Bonares MJ, Egeto P, de Oliveira Manoel AL, Vesely KA, Macdonald RL, Schweizer TA. Unruptured intracranial aneurysm treatment effects on cognitive function: a meta-analysis. Journal of Neurosurgery. 1-7. PMID 26381251 DOI: 10.3171/2014.12.Jns141625  0.025
2007 Rosengart AJ, Huo JD, Tolentino J, Novakovic RL, Frank JI, Goldenberg FD, Macdonald RL. Outcome in patients with subarachnoid hemorrhage treated with antiepileptic drugs. Journal of Neurosurgery. 107: 253-60. PMID 17695377 DOI: 10.3171/JNS-07/08/0253  0.025
2014 Macdonald RL. Occlusion of the M2: confusion about reperfusion. Journal of Neurosurgery. 121: 1351-2. PMID 25259567 DOI: 10.3171/2013.12.JNS132245  0.025
2005 Lo SE, Rosengart AJ, Novakovic RL, Kang UJ, Shah DN, Khan MA, Dalvi A, Goldenberg FD, Macdonald RL, Frank JI. Identification and treatment of cervical and oromandibular dystonia in acutely brain-injured patients. Neurocritical Care. 3: 139-45. PMID 16174883 DOI: 10.1385/Ncc:3:2:139  0.025
2022 Davies J, Spencer A, Macdonald S, Dobson L, Haydock E, Burton H, Angelopoulos G, Martin-Hirsch P, Wood N, Thangavelu A, Hutson R, Munot S, Flynn M, Smith M, Decruze B, ... ... Macdonald R, et al. Cervical cancer and COVID: an assessment of the initial effect of the pandemic and subsequent projection of impact for women in England: A cohort study. Bjog : An International Journal of Obstetrics and Gynaecology. PMID 35015334 DOI: 10.1111/1471-0528.17098  0.024
2015 Ayling OG, Ibrahim GM, Macdonald RL. Response. J Neurosurg. 123: 619-20. PMID 26668966  0.024
2015 Ayling OG, Ibrahim GM, Macdonald RL. Response. Journal of Neurosurgery. 123: 619-20. PMID 26561672  0.024
2013 Macdonald RL. Cavernous malformation. Journal of Neurosurgery. 118: 47-8; discussion 48-. PMID 23039147 DOI: 10.3171/2012.4.JNS12592  0.024
2011 Etminan N, Vergouwen MD, Ilodigwe D, Macdonald RL. Effect of pharmaceutical treatment on vasospasm, delayed cerebral ischemia, and clinical outcome in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1443-51. PMID 21285966 DOI: 10.1038/jcbfm.2011.7  0.024
2007 Macdonald R, Kirwan J, Roberts S, Gray D, Allsopp L, Green J. Ovarian cancer and ascites: A questionnaire on current management in the United kingdom. Journal of Palliative Medicine. 9: 1264-70. PMID 17187534 DOI: 10.1089/jpm.2006.9.1264  0.024
2005 Rosen D, Novakovic R, Goldenberg FD, Huo D, Baldwin ME, Frank JI, Rosengart AJ, Macdonald RL. Racial differences in demographics, acute complications, and outcomes in patients with subarachnoid hemorrhage: a large patient series. Journal of Neurosurgery. 103: 18-24. PMID 16121968 DOI: 10.3171/Jns.2005.103.1.0018  0.024
2013 Etminan N, Vergouwen MD, Macdonald RL. Angiographic vasospasm versus cerebral infarction as outcome measures after aneurysmal subarachnoid hemorrhage. Acta Neurochirurgica. Supplement. 115: 33-40. PMID 22890640 DOI: 10.1007/978-3-7091-1192-5_8  0.023
2006 Das S, Bendok BR, Novakovic RL, Parkinson RJ, Rosengart AJ, Macdonald RL, Frank JI. Return of vision after transarterial coiling of a carotid cavernous sinus fistula: case report. Surgical Neurology. 66: 82-5; discussion 85. PMID 16793452 DOI: 10.1016/j.surneu.2005.10.008  0.023
2014 Tso M, Macdonald RL. Lateral canthotomy: part of a neurosurgeon's toolkit? World Neurosurgery. 82: e189-90. PMID 24103550 DOI: 10.1016/j.wneu.2013.10.004  0.023
2006 Frontera JA, Claassen J, Schmidt JM, Wartenberg KE, Temes R, Connolly ES, MacDonald RL, Mayer SA. Prediction of symptomatic vasospasm after subarachnoid hemorrhage: the modified fisher scale. Neurosurgery. 59: 21-7; discussion 21-. PMID 16823296 DOI: 10.1227/01.Neu.0000218821.34014.1B  0.023
2011 Ibrahim GM, Weidauer S, Macdonald RL. Interobserver variability in the interpretation of computed tomography following aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery. 115: 1191-6. PMID 21819195 DOI: 10.3171/2011.7.JNS11725  0.023
2015 Lo BW, Fukuda H, Nishimura Y, Macdonald RL, Farrokhyar F, Thabane L, Levine MA. Pathophysiologic mechanisms of brain-body associations in ruptured brain aneurysms: A systematic review. Surgical Neurology International. 6: 136. PMID 26322246 DOI: 10.4103/2152-7806.162677  0.023
2012 Macdonald RL. Ischemia. Journal of Neurosurgery. 116: 643-6; discussion 64. PMID 22098197 DOI: 10.3171/2011.8.JNS111226  0.022
2013 Sehba FA, Pluta RM, Macdonald RL. Brain injury after transient global cerebral ischemia and subarachnoid hemorrhage. Stroke Research and Treatment. 2013: 827154. PMID 24327930 DOI: 10.1155/2013/827154  0.022
2013 Macdonald RL, Jaja B, Cusimano MD, Etminan N, Hanggi D, Hasan D, Ilodigwe D, Lantigua H, Le Roux P, Lo B, Louffat-Olivares A, Mayer S, Molyneux A, Quinn A, Schweizer TA, et al. SAHIT Investigators--on the outcome of some subarachnoid hemorrhage clinical trials. Translational Stroke Research. 4: 286-96. PMID 24323299 DOI: 10.1007/S12975-012-0242-1  0.022
2004 Baldwin ME, Macdonald RL, Huo D, Novakovic RL, Novakovia RL, Goldenberg FD, Frank JI, Rosengart AJ. Early vasospasm on admission angiography in patients with aneurysmal subarachnoid hemorrhage is a predictor for in-hospital complications and poor outcome. Stroke; a Journal of Cerebral Circulation. 35: 2506-11. PMID 15472099 DOI: 10.1161/01.Str.0000144654.79393.Cf  0.022
2015 Jaja BN, Lingsma H, Steyerberg EW, Schweizer TA, Thorpe KE, Macdonald RL. Neuroimaging characteristics of ruptured aneurysm as predictors of outcome after aneurysmal subarachnoid hemorrhage: pooled analyses of the SAHIT cohort. Journal of Neurosurgery. 1-9. PMID 26495952 DOI: 10.3171/2015.4.Jns142753  0.021
2012 Ibrahim GM, Vachhrajani S, Ilodigwe D, Kassell NF, Mayer SA, Ruefenacht D, Schmiedek P, Weidauer S, Pasqualin A, Macdonald RL. Method of aneurysm treatment does not affect clot clearance after aneurysmal subarachnoid hemorrhage. Neurosurgery. 70: 102-9; discussion 10. PMID 21788917 DOI: 10.1227/NEU.0b013e31822e5a8e  0.021
2012 MacDonald R, Shildrick T. Youth and wellbeing: experiencing bereavement and ill health in marginalised young people's transitions. Sociology of Health & Illness. 35: 147-61. PMID 22742572 DOI: 10.1111/j.1467-9566.2012.01488.x  0.021
2014 Bonares MJ, de Oliveira Manoel AL, Macdonald RL, Schweizer TA. Behavioral profile of unruptured intracranial aneurysms: a systematic review. Annals of Clinical and Translational Neurology. 1: 220-32. PMID 25356400 DOI: 10.1002/Acn3.41  0.021
2005 Schomas DA, Roeske JC, MacDonald RL, Sweeney PJ, Mehta N, Mundt AJ. Predictors of tumor control in patients treated with linac-based stereotactic radiosurgery for metastatic disease to the brain. American Journal of Clinical Oncology. 28: 180-7. PMID 15803014 DOI: 10.1097/01.coc.0000143017.69880.04  0.021
2003 Macdonald RL, Rosengart A, Huo D, Karrison T. Factors associated with the development of vasospasm after planned surgical treatment of aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery. 99: 644-52. PMID 14567598 DOI: 10.3171/Jns.2003.99.4.0644  0.021
2013 Saleem MA, Macdonald RL. Cerebral aneurysm presenting with aseptic meningitis: a case report. Journal of Medical Case Reports. 7: 244. PMID 24139091 DOI: 10.1186/1752-1947-7-244  0.02
2014 Fukuda H, Iwasaki K, Murao K, Yamagata S, Lo BW, Macdonald RL. Risk factors and consequences of unexpected trapping for ruptured anterior communicating artery aneurysms. Surgical Neurology International. 5: 106. PMID 25101201 DOI: 10.4103/2152-7806.136701  0.02
2014 Ladowski D, Qian W, Kapadia AN, Macdonald RL, Schweizer TA. Effect of aneurysmal subarachnoid hemorrhage on word generation. Behavioural Neurology. 2014: 610868. PMID 24803729 DOI: 10.1155/2014/610868  0.02
2015 MacDonald RL, Thomas CG. Dynamic trajectory-based couch motion for improvement of radiation therapy trajectories in cranial SRT. Medical Physics. 42: 2317-25. PMID 25979026 DOI: 10.1118/1.4917165  0.02
1999 Lowenstein DH, Macdonald RL. Panel discussion: Discussion and questions from the audience Epilepsia. 40: S21-S22.  0.02
2004 Rosen DS, Macdonald RL. Grading of subarachnoid hemorrhage: modification of the world World Federation of Neurosurgical Societies scale on the basis of data for a large series of patients. Neurosurgery. 54: 566-75; discussion 5. PMID 15028129 DOI: 10.1227/01.Neu.0000108862.32404.A5  0.019
2010 Decruze SB, Macdonald R, Smith G, Herod JJ. Paracentesis in ovarian cancer: a study of the physiology during free drainage of ascites. Journal of Palliative Medicine. 13: 251-4. PMID 19929225 DOI: 10.1089/jpm.2009.0158  0.019
2001 Macdonald RL, Ono S, Johns L, Marton LS, Weir B, Zhang ZD, Yamini B, Komuro T, Ahmed I, Stoodley M. Molecular weight interactions in experimental vasospasm. Acta Neurochirurgica. Supplement. 77: 115-7. PMID 11563267 DOI: 10.1007/978-3-7091-6232-3_25  0.019
2023 Robar JL, Cherpak A, MacDonald RL, Yashayaeva A, McAloney D, McMaster N, Zhan K, Cwajna S, Patil N, Dahn H. Novel Technology Allowing Cone Beam Computed Tomography in 6 Seconds: A Patient Study of Comparative Image Quality. Practical Radiation Oncology. PMID 37939844 DOI: 10.1016/j.prro.2023.10.014  0.019
2000 Foroohar M, Macdonald RL, Roth S, Stoodley M, Weir B. Intraoperative variables and early outcome after aneurysm surgery. Surgical Neurology. 54: 304-15. PMID 11136985 DOI: 10.1016/S0090-3019(00)00294-9  0.019
2007 Fergusen S, Macdonald RL. Predictors of cerebral infarction in patients with aneurysmal subarachnoid hemorrhage. Neurosurgery. 60: 658-67; discussion 6. PMID 17415202 DOI: 10.1227/01.NEU.0000255396.23280.31  0.019
2001 Zhang ZD, Marton LS, Ono S, Komuro T, Weir B, Macdonald RL. Complimentary deoxyribonucleic acid array analysis of cerebral arteries after experimental subarachnoid hemorrhage. Acta Neurochirurgica. Supplement. 77: 17-9. PMID 11563279 DOI: 10.1007/978-3-7091-6232-3_4  0.019
2001 Zhang ZD, Yamini B, Komuro T, Ono S, Johns L, Marton LS, Weir B, Macdonald RL. Delayed clot removal and experimental vasospasm. Acta Neurochirurgica. Supplement. 77: 33-5. PMID 11563304 DOI: 10.1007/978-3-7091-6232-3_8  0.019
2010 Tam AK, Ilodigwe D, Mocco J, Mayer S, Kassell N, Ruefenacht D, Schmiedek P, Weidauer S, Pasqualin A, Macdonald RL. Impact of systemic inflammatory response syndrome on vasospasm, cerebral infarction, and outcome after subarachnoid hemorrhage: exploratory analysis of CONSCIOUS-1 database. Neurocritical Care. 13: 182-9. PMID 20593247 DOI: 10.1007/s12028-010-9402-x  0.018
2003 Torres IJ, Mundt AJ, Sweeney PJ, Llanes-Macy S, Dunaway L, Castillo M, Macdonald RL. A longitudinal neuropsychological study of partial brain radiation in adults with brain tumors. Neurology. 60: 1113-8. PMID 12682316  0.018
2013 Lo BW, Macdonald RL, Baker A, Levine MA. Clinical outcome prediction in aneurysmal subarachnoid hemorrhage using Bayesian neural networks with fuzzy logic inferences. Computational and Mathematical Methods in Medicine. 2013: 904860. PMID 23690884 DOI: 10.1155/2013/904860  0.017
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