Edward Bertram - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Neuroscience Biology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bertram EH. The case against secondary epileptogenesis. Epilepsy Research. 107179. PMID 37336709 DOI: 10.1016/j.eplepsyres.2023.107179  0.326
2021 Wang Y, Anzivino MJ, Zhang Y, Bertram EH, Woznak J, Klibanov AL, Dumont E, Wintermark M, Lee KS. Noninvasive disconnection of targeted neuronal circuitry sparing axons of passage and nonneuronal cells. Journal of Neurosurgery. 1-11. PMID 34798617 DOI: 10.3171/2021.7.JNS21123  0.301
2021 Zhang Y, Buckmaster PS, Qiu L, Wang J, Keunen O, Ghobadi SN, Huang A, Hou Q, Li N, Narang S, Habte FG, Bertram EH, Lee KS, Wintermark M. Non-invasive, neurotoxic surgery reduces seizures in a rat model of temporal lobe epilepsy. Experimental Neurology. 113761. PMID 33991523 DOI: 10.1016/j.expneurol.2021.113761  0.385
2020 Mathern GW, Bertram EH. Recurrent limbic seizures do not cause hippocampal neuronal loss: A prolonged laboratory study. Neurobiology of Disease. 105183. PMID 33207277 DOI: 10.1016/j.nbd.2020.105183  0.513
2020 Benbadis SR, Beniczky S, Bertram E, MacIver S, Moshé SL. The role of EEG in patients with suspected epilepsy. Epileptic Disorders : International Epilepsy Journal With Videotape. 22: 143-155. PMID 32364504 DOI: 10.1684/Epd.2020.1151  0.423
2020 Zhang Y, Zhou H, Qu H, Liao C, Jiang H, Huang S, Ghobadi SN, Telichko A, Li N, Habte FG, Doyle T, Woznak JP, Bertram EH, Lee KS, Wintermark M. Effects of Non-invasive, Targeted, Neuronal Lesions on Seizures in a Mouse Model of Temporal Lobe Epilepsy. Ultrasound in Medicine & Biology. PMID 32081583 DOI: 10.1016/J.Ultrasmedbio.2020.01.008  0.516
2019 Nigam A, Hargus NJ, Barker BS, Ottolini M, Hounshell JA, Bertram EH, Perez-Reyes E, Patel MK. Inhibition of T-Type calcium channels in mEC layer II stellate neurons reduces neuronal hyperexcitability associated with epilepsy. Epilepsy Research. 154: 132-138. PMID 31132598 DOI: 10.1016/J.Eplepsyres.2019.05.006  0.763
2017 Tansel Kendirli M, Bertram EH. Genetic resistance to kindling associated with alterations in circuit function. Neurobiology of Disease. PMID 28602856 DOI: 10.1016/j.nbd.2017.06.002  0.32
2014 Bertram EH. Extratemporal lobe circuits in temporal lobe epilepsy. Epilepsy & Behavior : E&B. 38: 13-8. PMID 25238899 DOI: 10.1016/j.yebeh.2014.07.012  0.324
2014 Bertram EH. Electrophysiology in epilepsy surgery: Roles and limitations. Annals of Indian Academy of Neurology. 17: S40-4. PMID 24791088 DOI: 10.4103/0972-2327.128649  0.324
2013 Hargus NJ, Nigam A, Bertram EH, Patel MK. Evidence for a role of Nav1.6 in facilitating increases in neuronal hyperexcitability during epileptogenesis. Journal of Neurophysiology. 110: 1144-57. PMID 23741036 DOI: 10.1152/Jn.00383.2013  0.778
2013 Bertram EH. Neuronal circuits in epilepsy: do they matter? Experimental Neurology. 244: 67-74. PMID 22342991 DOI: 10.1016/j.expneurol.2012.01.028  0.443
2012 Hargus NJ, Jennings C, Perez-Reyes E, Bertram EH, Patel MK. Enhanced actions of adenosine in medial entorhinal cortex layer II stellate neurons in temporal lobe epilepsy are mediated via A(1)-receptor activation. Epilepsia. 53: 168-76. PMID 22126400 DOI: 10.1111/J.1528-1167.2011.03337.X  0.766
2011 Sloan DM, Zhang D, Bertram EH. Excitatory amplification through divergent-convergent circuits: the role of the midline thalamus in limbic seizures. Neurobiology of Disease. 43: 435-45. PMID 21554957 DOI: 10.1016/j.nbd.2011.04.017  0.314
2011 Sloan DM, Zhang D, Bertram EH. Increased GABAergic inhibition in the midline thalamus affects signaling and seizure spread in the hippocampus-prefrontal cortex pathway. Epilepsia. 52: 523-30. PMID 21204829 DOI: 10.1111/j.1528-1167.2010.02919.x  0.355
2011 Hargus NJ, Merrick EC, Nigam A, Kalmar CL, Baheti AR, Bertram EH, Patel MK. Temporal lobe epilepsy induces intrinsic alterations in Na channel gating in layer II medial entorhinal cortex neurons. Neurobiology of Disease. 41: 361-76. PMID 20946956 DOI: 10.1016/J.Nbd.2010.10.004  0.776
2010 Dudek FE, Bertram EH. Counterpoint to "what is an epileptic seizure?" by D'Ambrosio and Miller. Epilepsy Currents / American Epilepsy Society. 10: 91-4. PMID 20697504 DOI: 10.1111/j.1535-7511.2010.01368.x  0.349
2010 de Haan GJ, van der Geest P, Doelman G, Bertram E, Edelbroek P. A comparison of midazolam nasal spray and diazepam rectal solution for the residential treatment of seizure exacerbations. Epilepsia. 51: 478-82. PMID 19817813 DOI: 10.1111/J.1528-1167.2009.02333.X  0.383
2009 Hargus NJ, Bertram EH, Patel MK. Adenosine A1 receptors presynaptically modulate excitatory synaptic input onto subiculum neurons. Brain Research. 1280: 60-8. PMID 19450566 DOI: 10.1016/J.Brainres.2009.05.027  0.735
2009 Rajasekaran K, Sun C, Bertram EH. Altered pharmacology and GABA-A receptor subunit expression in dorsal midline thalamic neurons in limbic epilepsy. Neurobiology of Disease. 33: 119-32. PMID 18992345 DOI: 10.1016/J.Nbd.2008.09.023  0.526
2009 Jones PJ, Merrick EC, Batts TW, Hargus NJ, Wang Y, Stables JP, Bertram EH, Brown ML, Patel MK. Modulation of sodium channel inactivation gating by a novel lactam: implications for seizure suppression in chronic limbic epilepsy. The Journal of Pharmacology and Experimental Therapeutics. 328: 201-12. PMID 18952887 DOI: 10.1124/Jpet.108.144709  0.76
2009 Bertram EH. Temporal lobe epilepsy: where do the seizures really begin? Epilepsy & Behavior : E&B. 14: 32-7. PMID 18848643 DOI: 10.1016/j.yebeh.2008.09.017  0.361
2008 Dudek FE, Bertram EH. In search of a new and improved target for antiepileptic drugs: sialic acid? Epilepsy Currents / American Epilepsy Society. 8: 79-80. PMID 18488062 DOI: 10.1111/j.1535-7511.2008.00245.x  0.497
2008 Lehrmann E, Guidetti P, Löve A, Williamson J, Bertram EH, Schwarcz R. Glial activation precedes seizures and hippocampal neurodegeneration in measles virus-infected mice. Epilepsia. 49: 13-23. PMID 18226168 DOI: 10.1111/j.1528-1167.2008.01489.x  0.474
2008 Bertram EH, Zhang D, Williamson JM. Multiple roles of midline dorsal thalamic nuclei in induction and spread of limbic seizures. Epilepsia. 49: 256-68. PMID 18028408 DOI: 10.1111/j.1528-1167.2007.01408.x  0.339
2007 Rajasekaran K, Kapur J, Bertram EH. Alterations in GABA(A) receptor mediated inhibition in adjacent dorsal midline thalamic nuclei in a rat model of chronic limbic epilepsy. Journal of Neurophysiology. 98: 2501-8. PMID 17855591 DOI: 10.1152/Jn.00139.2007  0.437
2007 Bertram E. The relevance of kindling for human epilepsy. Epilepsia. 48: 65-74. PMID 17571354 DOI: 10.1111/J.1528-1167.2007.01068.X  0.451
2007 Sun C, Mtchedlishvili Z, Bertram EH, Erisir A, Kapur J. Selective loss of dentate hilar interneurons contributes to reduced synaptic inhibition of granule cells in an electrical stimulation-based animal model of temporal lobe epilepsy. The Journal of Comparative Neurology. 500: 876-93. PMID 17177260 DOI: 10.1002/Cne.21207  0.375
2006 Quigg M, Kiely JM, Johnson ML, Straume M, Bertram EH, Evans WS. Interictal and postictal circadian and ultradian luteinizing hormone secretion in men with temporal lobe epilepsy. Epilepsia. 47: 1452-9. PMID 16981860 DOI: 10.1111/j.1528-1167.2006.00617.x  0.318
2006 Vartanian MG, Radulovic LL, Kinsora JJ, Serpa KA, Vergnes M, Bertram E, Taylor CP. Activity profile of pregabalin in rodent models of epilepsy and ataxia. Epilepsy Research. 68: 189-205. PMID 16337109 DOI: 10.1016/J.Eplepsyres.2005.11.001  0.473
2005 Zhang DX, Williamson JM, Wu HQ, Schwarcz R, Bertram EH. In situ-produced 7-chlorokynurenate has different effects on evoked responses in rats with limbic epilepsy in comparison to naive controls. Epilepsia. 46: 1708-15. PMID 16302850 DOI: 10.1111/j.1528-1167.2005.00281.x  0.398
2005 Wu HQ, Rassoulpour A, Goodman JH, Scharfman HE, Bertram EH, Schwarcz R. Kynurenate and 7-chlorokynurenate formation in chronically epileptic rats. Epilepsia. 46: 1010-6. PMID 16026552 DOI: 10.1111/j.1528-1167.2005.67404.x  0.383
2004 Schmidt D, Bertram E, Ryvlin P, Lüders HO. The impact of temporal lobe surgery on cure and mortality of drug-resistant epilepsy: summary of a workshop. Epilepsy Research. 56: 83-4. PMID 14642991 DOI: 10.1016/J.Eplepsyres.2003.10.005  0.399
2003 Bertram EH. Why does surgery fail to cure limbic epilepsy? Seizure functional anatomy may hold the answer. Epilepsy Research. 56: 93-9. PMID 14642993  0.332
2002 Quigg M, Kiely JM, Shneker B, Veldhuis JD, Bertram EH. Interictal and postictal alterations of pulsatile secretions of luteinizing hormone in temporal lobe epilepsy in men. Annals of Neurology. 51: 559-66. PMID 12112101 DOI: 10.1002/ana.10188  0.328
2001 Bertram EH, Mangan PS, Zhang D, Scott CA, Williamson JM. The midline thalamus: alterations and a potential role in limbic epilepsy. Epilepsia. 42: 967-78. PMID 11554881 DOI: 10.1046/j.1528-1157.2001.042008967.x  0.352
2001 Chen ZF, Kamiryo T, Henson SL, Yamamoto H, Bertram EH, Schottler F, Patel F, Steiner L, Prasad D, Kassell NF, Shareghis S, Lee KS. Anticonvulsant effects of gamma surgery in a model of chronic spontaneous limbic epilepsy in rats. Journal of Neurosurgery. 94: 270-80. PMID 11213965 DOI: 10.3171/jns.2001.94.2.0270  0.442
2000 Borris DJ, Bertram EH, Kapur J. Ketamine controls prolonged status epilepticus. Epilepsy Research. 42: 117-22. PMID 11074184 DOI: 10.1016/S0920-1211(00)00175-3  0.321
2000 Mangan PS, Scott CA, Williamson JM, Bertram EH. Aberrant neuronal physiology in the basal nucleus of the amygdala in a model of chronic limbic epilepsy. Neuroscience. 101: 377-91. PMID 11074161 DOI: 10.1016/S0306-4522(00)00358-4  0.583
2000 Bertram EH, Scott C. The pathological substrate of limbic epilepsy: neuronal loss in the medial dorsal thalamic nucleus as the consistent change. Epilepsia. S3-8. PMID 10999511 DOI: 10.1111/j.1528-1157.2000.tb01548.x  0.409
2000 Quigg M, Clayburn H, Straume M, Menaker M, Bertram EH. Effects of circadian regulation and rest-activity state on spontaneous seizures in a rat model of limbic epilepsy. Epilepsia. 41: 502-9. PMID 10802754 DOI: 10.1111/J.1528-1157.2000.Tb00202.X  0.34
2000 Chen ZF, Schottler F, Bertram E, Gall CM, Anzivino MJ, Lee KS. Distribution and initiation of seizure activity in a rat brain with subcortical band heterotopia. Epilepsia. 41: 493-501. PMID 10802753 DOI: 10.1111/J.1528-1157.2000.Tb00201.X  0.59
1999 Quigg M, Clayburn H, Straume M, Menaker M, Bertram EH. Hypothalamic neuronal loss and altered circadian rhythm of temperature in a rat model of mesial temporal lobe epilepsy. Epilepsia. 40: 1688-96. PMID 10612331 DOI: 10.1111/J.1528-1157.1999.Tb01585.X  0.43
1998 Bertram EH, Zhang DX, Mangan P, Fountain N, Rempe D. Functional anatomy of limbic epilepsy: a proposal for central synchronization of a diffusely hyperexcitable network. Epilepsy Research. 32: 194-205. PMID 9761320 DOI: 10.1016/S0920-1211(98)00051-5  0.393
1998 Mathern GW, Pretorius JK, Leite JP, Kornblum HI, Mendoza D, Lozada A, Bertram EH. Hippocampal AMPA and NMDA mRNA levels and subunit immunoreactivity in human temporal lobe epilepsy patients and a rodent model of chronic mesial limbic epilepsy. Epilepsy Research. 32: 154-71. PMID 9761317 DOI: 10.1016/S0920-1211(98)00048-5  0.419
1998 Mangan PS, Bertram EH. Ontogeny of altered synaptic function in a rat model of chronic temporal lobe epilepsy. Brain Research. 799: 183-96. PMID 9675275 DOI: 10.1016/S0006-8993(98)00411-9  0.455
1998 Fountain NB, Bear J, Bertram EH, Lothman EW. Responses of deep entorhinal cortex are epileptiform in an electrogenic rat model of chronic temporal lobe epilepsy. Journal of Neurophysiology. 80: 230-40. PMID 9658044  0.486
1997 Bertram EH, Williamson JM, Cornett JF, Spradlin S, Chen ZF. Design and construction of a long-term continuous video-EEG monitoring unit for simultaneous recording of multiple small animals. Brain Research. Brain Research Protocols. 2: 85-97. PMID 9438076 DOI: 10.1016/S1385-299X(97)00033-0  0.352
1997 Rempe DA, Bertram EH, Williamson JM, Lothman EW. Interneurons in area CA1 stratum radiatum and stratum oriens remain functionally connected to excitatory synaptic input in chronically epileptic animals. Journal of Neurophysiology. 78: 1504-15. PMID 9310439  0.394
1997 Mangan PS, Bertram EH. Shortened-duration GABA(A) receptor-mediated synaptic potentials underlie enhanced CA1 excitability in a chronic model of temporal lobe epilepsy. Neuroscience. 80: 1101-11. PMID 9284063 DOI: 10.1016/S0306-4522(97)00148-6  0.366
1997 Mathern GW, Bertram EH, Babb TL, Pretorius JK, Kuhlman PA, Spradlin S, Mendoza D. In contrast to kindled seizures, the frequency of spontaneous epilepsy in the limbic status model correlates with greater aberrant fascia dentata excitatory and inhibitory axon sprouting, and increased staining for N-methyl-D-aspartate, AMPA and GABA(A) receptors. Neuroscience. 77: 1003-19. PMID 9130782 DOI: 10.1016/S0306-4522(96)00516-7  0.499
1997 Bertram EH. Functional anatomy of spontaneous seizures in a rat model of limbic epilepsy. Epilepsia. 38: 95-105. PMID 9024190 DOI: 10.1111/j.1528-1157.1997.tb01083.x  0.357
1997 Lee KS, Schottler F, Collins JL, Lanzino G, Couture D, Rao A, Hiramatsu K, Goto Y, Hong S, Caner H, Yamamoto H, Chen Z, Bertram E, Berr S, Omary R, et al. A Genetic Animal Model of Human Neocortical Heterotopia Associated with Seizures The Journal of Neuroscience. 17: 6236-6242. DOI: 10.1523/Jneurosci.17-16-06236.1997  0.495
1994 Bertram EH, Cornett JF. The evolution of a rat model of chronic spontaneous limbic seizures. Brain Research. 661: 157-62. PMID 7834366 DOI: 10.1016/0006-8993(94)91192-4  0.36
1993 Bertram EH, Cornett J. The ontogeny of seizures in a rat model of limbic epilepsy: evidence for a kindling process in the development of chronic spontaneous seizures. Brain Research. 625: 295-300. PMID 8275310 DOI: 10.1016/0006-8993(93)91071-Y  0.347
1993 Du F, Williamson J, Bertram E, Lothman E, Okuno E, Schwarcz R. Kynurenine pathway enzymes in a rat model of chronic epilepsy: immunohistochemical study of activated glial cells. Neuroscience. 55: 975-89. PMID 8232907 DOI: 10.1016/0306-4522(93)90312-4  0.436
1991 Lothman EW, Bertram EH, Stringer JL. Functional anatomy of hippocampal seizures. Progress in Neurobiology. 37: 1-82. PMID 1947175 DOI: 10.1016/0301-0082(91)90011-O  0.342
1990 Lothman EW, Bertram EH, Kapur J, Stringer JL. Recurrent spontaneous hippocampal seizures in the rat as a chronic sequela to limbic status epilepticus. Epilepsy Research. 6: 110-8. PMID 2387285 DOI: 10.1016/0920-1211(90)90085-A  0.386
1990 Bertram EH, Lothman EW, Lenn NJ. The hippocampus in experimental chronic epilepsy: a morphometric analysis. Annals of Neurology. 27: 43-8. PMID 2301927 DOI: 10.1002/ana.410270108  0.494
1990 Bertram EH, Lothman EW. NMDA receptor antagonists and limbic status epilepticus: a comparison with standard anticonvulsants. Epilepsy Research. 5: 177-84. PMID 2166658 DOI: 10.1016/0920-1211(90)90036-U  0.309
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