Margaret A. Shupnik - Publications

University of Virginia, Charlottesville, VA 
Neuroscience Biology, Endocrinology Biology

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Modesitt SC, Hallowell PT, Slack-Davis JK, Michalek RD, Atkins KA, Kelley SL, Arapovic S, Shupnik MA, Hoehn K. Women at extreme risk for obesity-related carcinogenesis: Baseline endometrial pathology and impact of bariatric surgery on weight, metabolic profiles and quality of life. Gynecologic Oncology. PMID 26013696 DOI: 10.1016/j.ygyno.2015.05.015  1
2015 Bagchi D, Andrade J, Shupnik MA. A new role for wilms tumor protein 1: differential activities of + KTS and -KTS variants to regulate LHβ transcription. Plos One. 10: e0116825. PMID 25617744 DOI: 10.1371/journal.pone.0116825  1
2014 Young NA, Wu LC, Burd CJ, Friedman AK, Kaffenberger BH, Rajaram MV, Schlesinger LS, James H, Shupnik MA, Jarjour WN. Estrogen modulation of endosome-associated toll-like receptor 8: an IFNα-independent mechanism of sex-bias in systemic lupus erythematosus. Clinical Immunology (Orlando, Fla.). 151: 66-77. PMID 24525049 DOI: 10.1016/j.clim.2014.01.006  1
2009 Chu Z, Andrade J, Shupnik MA, Moenter SM. Differential regulation of gonadotropin-releasing hormone neuron activity and membrane properties by acutely applied estradiol: dependence on dose and estrogen receptor subtype. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5616-27. PMID 19403828 DOI: 10.1523/JNEUROSCI.0352-09.2009  1
2009 Walsh HE, Shupnik MA. Proteasome regulation of dynamic transcription factor occupancy on the GnRH-stimulated luteinizing hormone beta-subunit promoter. Molecular Endocrinology (Baltimore, Md.). 23: 237-50. PMID 19095772 DOI: 10.1210/me.2008-0098  1
2008 Fox EM, Bernaciak TM, Wen J, Weaver AM, Shupnik MA, Silva CM. Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 22: 1781-96. PMID 18550772 DOI: 10.1210/me.2007-0419  1
2008 Haisenleder DJ, Burger LL, Walsh HE, Stevens J, Aylor KW, Shupnik MA, Marshall JC. Pulsatile gonadotropin-releasing hormone stimulation of gonadotropin subunit transcription in rat pituitaries: evidence for the involvement of Jun N-terminal kinase but not p38. Endocrinology. 149: 139-45. PMID 17932215 DOI: 10.1210/en.2007-1113  1
2007 Kowase T, Walsh HE, Darling DS, Shupnik MA. Estrogen enhances gonadotropin-releasing hormone-stimulated transcription of the luteinizing hormone subunit promoters via altered expression of stimulatory and suppressive transcription factors. Endocrinology. 148: 6083-91. PMID 17823254 DOI: 10.1210/en.2007-0407  1
2007 Ferris HA, Walsh HE, Stevens J, Fallest PC, Shupnik MA. Luteinizing hormone beta promoter stimulation by adenylyl cyclase and cooperation with gonadotropin-releasing hormone 1 in transgenic mice and LBetaT2 Cells. Biology of Reproduction. 77: 1073-80. PMID 17699734 DOI: 10.1095/biolreprod.107.064139  1
2006 Riggins RB, Thomas KS, Ta HQ, Wen J, Davis RJ, Schuh NR, Donelan SS, Owen KA, Gibson MA, Shupnik MA, Silva CM, Parsons SJ, Clarke R, Bouton AH. Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b. Cancer Research. 66: 7007-15. PMID 16849545 DOI: 10.1158/0008-5472.CAN-05-3952  1
2006 Ferris HA, Shupnik MA. Mechanisms for pulsatile regulation of the gonadotropin subunit genes by GNRH1. Biology of Reproduction. 74: 993-8. PMID 16481592 DOI: 10.1095/biolreprod.105.049049  1
2006 Bryant WM, Gibson MA, Shupnik MA. Stimulation of the novel estrogen receptor-alpha intronic TERP-1 promoter by estrogens, androgen, pituitary adenylate cyclase-activating peptide, and forskolin, and autoregulation by TERP-1 protein. Endocrinology. 147: 543-51. PMID 16210360 DOI: 10.1210/en.2005-1053  1
2005 Boerner JL, Gibson MA, Fox EM, Posner ED, Parsons SJ, Silva CM, Shupnik MA. Estrogen negatively regulates epidermal growth factor (EGF)-mediated signal transducer and activator of transcription 5 signaling in human EGF family receptor-overexpressing breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 19: 2660-70. PMID 15976008 DOI: 10.1210/me.2004-0439  1
2005 Haisenleder DJ, Burger LL, Aylor KW, Dalkin AC, Walsh HE, Shupnik MA, Marshall JC. Testosterone stimulates follicle-stimulating hormone beta transcription via activation of extracellular signal-regulated kinase: evidence in rat pituitary cells. Biology of Reproduction. 72: 523-9. PMID 15509729 DOI: 10.1095/biolreprod.104.035196  1
2004 Tsai HW, Katzenellenbogen JA, Katzenellenbogen BS, Shupnik MA. Protein kinase A activation of estrogen receptor α transcription does not require proteasome activity and protects the receptor from ligand-mediated degradation Endocrinology. 145: 2730-2738. PMID 15033909 DOI: 10.1210/en.2003-1470  1
2004 Curtin D, Ferris HA, Häkli M, Gibson M, Jänne OA, Palvimo JJ, Shupnik MA. Small nuclear RING finger protein stimulates the rat luteinizing hormone-beta promoter by interacting with Sp1 and steroidogenic factor-1 and protects from androgen suppression. Molecular Endocrinology (Baltimore, Md.). 18: 1263-76. PMID 14988433 DOI: 10.1210/me.2003-0221  1
2003 Lin VY, Resnick EM, Shupnik MA. Truncated estrogen receptor product-1 stimulates estrogen receptor alpha transcriptional activity by titration of repressor proteins. The Journal of Biological Chemistry. 278: 38125-31. PMID 12878603 DOI: 10.1074/jbc.M303882200  1
2003 Haisenleder DJ, Ferris HA, Shupnik MA. The calcium component of gonadotropin-releasing hormone-stimulated luteinizing hormone subunit gene transcription is mediated by calcium/calmodulin-dependent protein kinase type II. Endocrinology. 144: 2409-16. PMID 12746302 DOI: 10.1210/en.2002-0013  1
2002 Schreihofer DA, Rowe DF, Rissman EF, Scordalakes EM, Gustafsson J JÃ…, Shupnik MA. Estrogen receptor-alpha (ERalpha), but not ERbeta, modulates estrogen stimulation of the ERalpha-truncated variant, TERP-1. Endocrinology. 143: 4196-202. PMID 12399412 DOI: 10.1210/en.2002-220353  1
2002 Rissman EF, Heck AL, Leonard JE, Shupnik MA, Gustafsson JA. Disruption of estrogen receptor beta gene impairs spatial learning in female mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 3996-4001. PMID 11891272 DOI: 10.1073/pnas.012032699  1
2001 Schreihofer DA, Resnick EM, Lin VY, Shupnik MA. Ligand-independent activation of pituitary ER: dependence on PKA-stimulated pathways. Endocrinology. 142: 3361-8. PMID 11459779 DOI: 10.1210/endo.142.8.8333  1
2000 Schreihofer DA, Stoler MH, Shupnik MA. Differential Expression and Regulation of Estrogen Receptors (ERs) in Rat Pituitary and Cell Lines: Estrogen Decreases ERα Protein and Estrogen Responsiveness. Endocrinology. 141: 2174-2184. PMID 28204412 DOI: 10.1210/endo.141.6.7505  0.8
2000 Resnick EM, Schreihofer DA, Periasamy A, Shupnik MA. Truncated estrogen receptor product-1 suppresses estrogen receptor transactivation by dimerization with estrogen receptors alpha and beta. The Journal of Biological Chemistry. 275: 7158-66. PMID 10702284 DOI: 10.1074/jbc.275.10.7158  1
1999 Schreihofer DA, Resnick EM, Soh AY, Shupnik MA. Transcriptional regulation by a naturally occurring truncated rat estrogen receptor (ER), truncated ER product-1 (TERP-1). Molecular Endocrinology (Baltimore, Md.). 13: 320-9. PMID 9973261 DOI: 10.1210/mend.13.2.0236  1
1997 Friend KE, Resnick EM, Ang LW, Shupnik MA. Specific modulation of estrogen receptor mRNA isoforms in rat pituitary throughout the estrous cycle and in response to steroid hormones Molecular and Cellular Endocrinology. 131: 147-155. PMID 9296373 DOI: 10.1016/S0303-7207(97)00098-1  1
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