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Christopher James Donnelly, Ph.D. - Publications

Affiliations: 
Neurology Johns Hopkins University School of Medicine, Baltimore, MD, United States 
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16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Otte CG, Fortuna TR, Mann JR, Gleixner AM, Ramesh N, Pyles NJ, Pandey UB, Donnelly CJ. Optogenetic TDP-43 nucleation induces persistent insoluble species and progressive motor dysfunction in vivo. Neurobiology of Disease. 105078. PMID 32927062 DOI: 10.1016/J.Nbd.2020.105078  0.32
2020 Ortega JA, Daley EL, Kour S, Samani M, Tellez L, Smith HS, Hall EA, Esengul YT, Tsai YH, Gendron TF, Donnelly CJ, Siddique T, Savas JN, Pandey UB, Kiskinis E. Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity. Neuron. PMID 32059759 DOI: 10.1016/J.Neuron.2020.01.020  0.386
2019 Casci I, Krishnamurthy K, Kour S, Tripathy V, Ramesh N, Anderson EN, Marrone L, Grant RA, Oliver S, Gochenaur L, Patel K, Sterneckert J, Gleixner AM, Donnelly CJ, Ruepp MD, et al. Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization. Nature Communications. 10: 5583. PMID 31811140 DOI: 10.1038/S41467-019-13383-Z  0.354
2019 Mann JR, Gleixner AM, Mauna JC, Gomes E, DeChellis-Marks MR, Needham PG, Copley KE, Hurtle B, Portz B, Pyles NJ, Guo L, Calder CB, Wills ZP, Pandey UB, Kofler JK, ... ... Donnelly CJ, et al. RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43. Neuron. PMID 30826182 DOI: 10.1016/J.Neuron.2019.01.048  0.302
2015 Zhang K, Donnelly CJ, Haeusler AR, Grima JC, Machamer JB, Steinwald P, Daley EL, Miller SJ, Cunningham KM, Vidensky S, Gupta S, Thomas MA, Hong I, Chiu SL, Huganir RL, et al. The C9orf72 repeat expansion disrupts nucleocytoplasmic transport. Nature. 525: 56-61. PMID 26308891 DOI: 10.1038/Nature14973  0.362
2014 Donnelly CJ, Grima JC, Sattler R. Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets? Neurodegenerative Disease Management. 4: 417-37. PMID 25531686 DOI: 10.2217/Nmt.14.36  0.328
2014 Haeusler AR, Donnelly CJ, Periz G, Simko EA, Shaw PG, Kim MS, Maragakis NJ, Troncoso JC, Pandey A, Sattler R, Rothstein JD, Wang J. C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Nature. 507: 195-200. PMID 24598541 DOI: 10.1038/Nature13124  0.303
2013 Donnelly CJ, Zhang PW, Pham JT, Haeusler AR, Heusler AR, Mistry NA, Vidensky S, Daley EL, Poth EM, Hoover B, Fines DM, Maragakis N, Tienari PJ, Petrucelli L, Traynor BJ, et al. RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention. Neuron. 80: 415-28. PMID 24139042 DOI: 10.1016/J.Neuron.2013.10.015  0.329
2013 Yoo S, Kim HH, Kim P, Donnelly CJ, Kalinski AL, Vuppalanchi D, Park M, Lee SJ, Merianda TT, Perrone-Bizzozero NI, Twiss JL. A HuD-ZBP1 ribonucleoprotein complex localizes GAP-43 mRNA into axons through its 3' untranslated region AU-rich regulatory element. Journal of Neurochemistry. 126: 792-804. PMID 23586486 DOI: 10.1111/Jnc.12266  0.737
2013 Donnelly CJ, Park M, Spillane M, Yoo S, Pacheco A, Gomes C, Vuppalanchi D, McDonald M, Kim HH, Kim HK, Merianda TT, Gallo G, Twiss JL. Axonally synthesized β-actin and GAP-43 proteins support distinct modes of axonal growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3311-22. PMID 23426659 DOI: 10.1523/Jneurosci.1722-12.2013  0.699
2012 Spillane M, Ketschek A, Donnelly CJ, Pacheco A, Twiss JL, Gallo G. Nerve growth factor-induced formation of axonal filopodia and collateral branches involves the intra-axonal synthesis of regulators of the actin-nucleating Arp2/3 complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17671-89. PMID 23223289 DOI: 10.1523/Jneurosci.1079-12.2012  0.715
2012 Vuppalanchi D, Merianda TT, Donnelly C, Pacheco A, Williams G, Yoo S, Ratan RR, Willis DE, Twiss JL. Lysophosphatidic acid differentially regulates axonal mRNA translation through 5'UTR elements. Molecular and Cellular Neurosciences. 50: 136-46. PMID 22522146 DOI: 10.1016/J.Mcn.2012.04.001  0.725
2011 Willis DE, Xu M, Donnelly CJ, Tep C, Kendall M, Erenstheyn M, English AW, Schanen NC, Kirn-Safran CB, Yoon SO, Bassell GJ, Twiss JL. Axonal Localization of transgene mRNA in mature PNS and CNS neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14481-7. PMID 21994364 DOI: 10.1523/JNEUROSCI.2950-11.2011  0.729
2011 Donnelly CJ, Willis DE, Xu M, Tep C, Jiang C, Yoo S, Schanen NC, Kirn-Safran CB, van Minnen J, English A, Yoon SO, Bassell GJ, Twiss JL. Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity. The Embo Journal. 30: 4665-77. PMID 21964071 DOI: 10.1038/Emboj.2011.347  0.739
2010 Li S, Overman JJ, Katsman D, Kozlov SV, Donnelly CJ, Twiss JL, Giger RJ, Coppola G, Geschwind DH, Carmichael ST. An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke. Nature Neuroscience. 13: 1496-504. PMID 21057507 DOI: 10.1038/Nn.2674  0.63
2010 Donnelly CJ, Fainzilber M, Twiss JL. Subcellular communication through RNA transport and localized protein synthesis. Traffic (Copenhagen, Denmark). 11: 1498-505. PMID 21040295 DOI: 10.1111/J.1600-0854.2010.01118.X  0.656
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