Erwin G. Van Meir - Publications

Affiliations: 
Emory University, Atlanta, GA 
Area:
Neuroscience Biology, Cell Biology, Molecular Biology

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhang H, Zhu D, Zhang Z, Kaluz S, Yu B, Devi NS, Olson JJ, Van Meir EG. EZH2 targeting reduces medulloblastoma growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathway. Oncogene. PMID 31582835 DOI: 10.1038/s41388-019-1036-7  0.305
2018 Zhu D, Osuka S, Zhang Z, Reichert ZR, Yang L, Kanemura Y, Jiang Y, You S, Zhang H, Devi NS, Bhattacharya D, Takano S, Gillespie GY, Macdonald T, Tan C, ... ... Van Meir EG, et al. BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation. Cancer Cell. 33: 1004-1016.e5. PMID 29894688 DOI: 10.1016/J.Ccell.2018.05.006  0.315
2016 Bolyard CM, Meisen WH, Banasavadi-Siddegowda Y, Hardcastle J, Yoo JY, Wohleb ES, Wojton J, Yu JG, Dubin S, Khosla M, Xu B, Smith JG, Alvarez-Breckenridge C, Pow-Anpongkul P, Pichiorri F, ... ... Van Meir EG, et al. BAI1 Orchestrates Macrophage Inflammatory Response to HSV Infection- implications for Oncolytic Viral Therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27852701 DOI: 10.1158/1078-0432.Ccr-16-1818  0.626
2016 Aust G, Zhu D, Van Meir EG, Xu L. Adhesion GPCRs in Tumorigenesis. Handbook of Experimental Pharmacology. 234: 369-396. PMID 27832497 DOI: 10.1007/978-3-319-41523-9_17  0.324
2014 Wojton J, Meisen WH, Jacob NK, Thorne AH, Hardcastle J, Denton N, Chu Z, Dmitrieva N, Marsh R, Van Meir EG, Kwon CH, Chakravarti A, Qi X, Kaur B. SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma. Oncotarget. 5: 9703-9. PMID 25210852 DOI: 10.18632/Oncotarget.2232  0.697
2014 Zerrouqi A, Pyrzynska B, Brat DJ, Van Meir EG. P14ARF suppresses tumor-induced thrombosis by regulating the tissue factor pathway. Cancer Research. 74: 1371-8. PMID 24398474 DOI: 10.1158/0008-5472.Can-13-1951  0.316
2014 Van Meir EG, Lee S, Khwaja FW, Zerrouqi A, Zhang Z, Olson JJ, Kaluzova M, Hadjipanayis CG, Devi NS. A NOVEL P53 BYSTANDER EFFECT INDUCES GLIOBLASTOMA CELL DEATH THROUGH A GLYCOSYLATION-DEPENDENT MECHANISM Neuro-Oncology. 16: iii19-iii19. DOI: 10.1093/Neuonc/Nou206.70  0.767
2013 Stephenson JR, Paavola KJ, Schaefer SA, Kaur B, Van Meir EG, Hall RA. Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density. The Journal of Biological Chemistry. 288: 22248-56. PMID 23782696 DOI: 10.1074/Jbc.M113.489757  0.453
2012 Yin S, Kaluz S, Devi NS, Jabbar AA, de Noronha RG, Mun J, Zhang Z, Boreddy PR, Wang W, Wang Z, Abbruscato T, Chen Z, Olson JJ, Zhang R, Goodman MM, ... ... Van Meir EG, et al. Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 6623-33. PMID 22923450 DOI: 10.1158/1078-0432.Ccr-12-0861  0.343
2012 Zerrouqi A, Pyrzynska B, Febbraio M, Brat DJ, Van Meir EG. P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3. The Journal of Clinical Investigation. 122: 1283-95. PMID 22378045 DOI: 10.1172/Jci38596  0.355
2012 Yang FH, Zhang B, Zhou DJ, Bie L, Tom MW, Drummond DC, Nicolaides T, Mueller S, Banerjee A, Park JW, Prados MD, James DC, Gupta N, Hashizume R, Strohbehn GW, ... ... Van Meir EG, et al. LAB-EXPERIMENTAL (PRE-CLINICAL) THERAPEUTICS AND PHARMACOLOGY Neuro-Oncology. 14: vi25-vi37. DOI: 10.1093/Neuonc/Nos222  0.702
2012 Kijima N, Hosen N, Kagawa N, Hashimoto N, Chiba Y, Kinoshita M, Sugiyama H, Yoshimine T, Kim YZ, Kim KH, Lee EH, Hu B, Sim H, Mohan N, Agudelo-Garcia P, ... ... Van Meir EG, ... ... Van Meir EG, et al. LAB-CELL BIOLOGY AND SIGNALING Neuro-Oncology. 14: vi7-vi20. DOI: 10.1093/Neuonc/Nos220  0.699
2011 Mooring SR, Jin H, Devi NS, Jabbar AA, Kaluz S, Liu Y, Van Meir EG, Wang B. Design and synthesis of novel small-molecule inhibitors of the hypoxia inducible factor pathway. Journal of Medicinal Chemistry. 54: 8471-89. PMID 22032632 DOI: 10.1021/Jm201018G  0.303
2011 Zhu D, Hunter SB, Vertino PM, Van Meir EG. Overexpression of MBD2 in glioblastoma maintains epigenetic silencing and inhibits the antiangiogenic function of the tumor suppressor gene BAI1. Cancer Research. 71: 5859-70. PMID 21724586 DOI: 10.1158/0008-5472.Can-11-1157  0.33
2011 Cork SM, Van Meir EG. Emerging roles for the BAI1 protein family in the regulation of phagocytosis, synaptogenesis, neurovasculature, and tumor development. Journal of Molecular Medicine (Berlin, Germany). 89: 743-52. PMID 21509575 DOI: 10.1007/S00109-011-0759-X  0.765
2010 Klenotic PA, Huang P, Palomo J, Kaur B, Van Meir EG, Vogelbaum MA, Febbraio M, Gladson CL, Silverstein RL. Histidine-rich glycoprotein modulates the anti-angiogenic effects of vasculostatin. The American Journal of Pathology. 176: 2039-50. PMID 20167858 DOI: 10.2353/Ajpath.2010.090782  0.565
2009 Hadjipanayis CG, Van Meir EG. Brain cancer propagating cells: biology, genetics and targeted therapies. Trends in Molecular Medicine. 15: 519-30. PMID 19889578 DOI: 10.1016/J.Molmed.2009.09.003  0.317
2009 Kaur B, Cork SM, Sandberg EM, Devi NS, Zhang Z, Klenotic PA, Febbraio M, Shim H, Mao H, Tucker-Burden C, Silverstein RL, Brat DJ, Olson JJ, Van Meir EG. Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism. Cancer Research. 69: 1212-20. PMID 19176395 DOI: 10.1158/0008-5472.Can-08-1166  0.765
2007 Khwaja FW, Reed MS, Olson JJ, Schmotzer BJ, Gillespie GY, Guha A, Groves MD, Kesari S, Pohl J, Van Meir EG. Proteomic identification of biomarkers in the cerebrospinal fluid (CSF) of astrocytoma patients. Journal of Proteome Research. 6: 559-70. PMID 17269713 DOI: 10.1021/Pr060240Z  0.743
2006 Belozerov VE, Van Meir EG. Inhibitors of hypoxia-inducible factor-1 signaling. Current Opinion in Investigational Drugs (London, England : 2000). 7: 1067-76. PMID 17209524  0.316
2006 Kang SH, Cho HT, Devi S, Zhang Z, Escuin D, Liang Z, Mao H, Brat DJ, Olson JJ, Simons JW, Lavallee TM, Giannakakou P, Van Meir EG, Shim H. Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model. Cancer Research. 66: 11991-7. PMID 17178898 DOI: 10.1158/0008-5472.Can-06-1320  0.323
2006 Khwaja FW, Duke-Cohan JS, Brat DJ, Van Meir EG. Attractin is elevated in the cerebrospinal fluid of patients with malignant astrocytoma and mediates glioma cell migration. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6331-6. PMID 17085642 DOI: 10.1158/1078-0432.Ccr-06-1296  0.725
2006 Khwaja FW, Nolen JD, Mendrinos SE, Lewis MM, Olson JJ, Pohl J, Van Meir EG, Ritchie JC, Brat DJ. Proteomic analysis of cerebrospinal fluid discriminates malignant and nonmalignant disease of the central nervous system and identifies specific protein markers. Proteomics. 6: 6277-87. PMID 17078017 DOI: 10.1002/Pmic.200600135  0.712
2006 Khwaja FW, Svoboda P, Reed M, Pohl J, Pyrzynska B, Van Meir EG. Proteomic identification of the wt-p53-regulated tumor cell secretome. Oncogene. 25: 7650-61. PMID 17043663 DOI: 10.1038/Sj.Onc.1209969  0.755
2006 Rong Y, Durden DL, Van Meir EG, Brat DJ. 'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis. Journal of Neuropathology and Experimental Neurology. 65: 529-39. PMID 16783163 DOI: 10.1097/00005072-200606000-00001  0.339
2005 Belozerov VE, Van Meir EG. Hypoxia inducible factor-1: a novel target for cancer therapy. Anti-Cancer Drugs. 16: 901-9. PMID 16162966  0.312
2005 Kaur B, Khwaja FW, Severson EA, Matheny SL, Brat DJ, Van Meir EG. Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis. Neuro-Oncology. 7: 134-53. PMID 15831232 DOI: 10.1215/S1152851704001115  0.764
2005 Kaur B, Brat DJ, Devi NS, Van Meir EG. Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor. Oncogene. 24: 3632-42. PMID 15782143 DOI: 10.1038/Sj.Onc.1208317  0.567
2005 Tan C, de Noronha RG, Roecker AJ, Pyrzynska B, Khwaja F, Zhang Z, Zhang H, Teng Q, Nicholson AC, Giannakakou P, Zhou W, Olson JJ, Pereira MM, Nicolaou KC, Van Meir EG. Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway. Cancer Research. 65: 605-12. PMID 15695405  0.743
2004 Kaur B, Tan C, Brat DJ, Post DE, Van Meir EG. Genetic and hypoxic regulation of angiogenesis in gliomas. Journal of Neuro-Oncology. 70: 229-43. PMID 15674480 DOI: 10.1007/S11060-004-2752-5  0.526
2004 Post DE, Devi NS, Li Z, Brat DJ, Kaur B, Nicholson A, Olson JJ, Zhang Z, Van Meir EG. Cancer therapy with a replicating oncolytic adenovirus targeting the hypoxic microenvironment of tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8603-12. PMID 15623644 DOI: 10.1158/1078-0432.Ccr-04-1432  0.556
2004 Yang L, Cao Z, Li F, Post DE, Van Meir EG, Zhong H, Wood WC. Tumor-specific gene expression using the survivin promoter is further increased by hypoxia. Gene Therapy. 11: 1215-23. PMID 15141159 DOI: 10.1038/sj.gt.3302280  0.337
2004 Van Meir EG, Bellail A, Phuphanich S. Emerging molecular therapies for brain tumors. Seminars in Oncology. 31: 38-46. PMID 15124133  0.317
2004 Brat DJ, Van Meir EG. Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 397-405. PMID 14990981 DOI: 10.1038/Labinvest.3700070  0.306
2004 Brat DJ, Castellano-Sanchez AA, Hunter SB, Pecot M, Cohen C, Hammond EH, Devi SN, Kaur B, Van Meir EG. Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population. Cancer Research. 64: 920-7. PMID 14871821 DOI: 10.1158/0008-5472.Can-03-2073  0.539
2003 Song JH, Song DK, Pyrzynska B, Petruk KC, Van Meir EG, Hao C. TRAIL triggers apoptosis in human malignant glioma cells through extrinsic and intrinsic pathways. Brain Pathology (Zurich, Switzerland). 13: 539-53. PMID 14655759 DOI: 10.1111/J.1750-3639.2003.Tb00484.X  0.312
2003 Post DE, Van Meir EG. A novel hypoxia-inducible factor (HIF) activated oncolytic adenovirus for cancer therapy. Oncogene. 22: 2065-72. PMID 12687009 DOI: 10.1038/sj.onc.1206464  0.306
2003 Kaur B, Brat DJ, Calkins CC, Van Meir EG. Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression. The American Journal of Pathology. 162: 19-27. PMID 12507886 DOI: 10.1016/S0002-9440(10)63794-7  0.514
2003 Brat DJ, Kaur B, Van Meir EG. Genetic modulation of hypoxia induced gene expression and angiogenesis: relevance to brain tumors. Frontiers in Bioscience : a Journal and Virtual Library. 8: d100-16. PMID 12456339  0.527
2002 Albertoni M, Shaw PH, Nozaki M, Godard S, Tenan M, Hamou MF, Fairlie DW, Breit SN, Paralkar VM, de Tribolet N, Van Meir EG, Hegi ME. Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1. Oncogene. 21: 4212-9. PMID 12082608 DOI: 10.1038/sj.onc.1205610  0.332
2002 Fulci G, Ishii N, Maurici D, Gernert KM, Hainaut P, Kaur B, Van Meir EG. Initiation of human astrocytoma by clonal evolution of cells with progressive loss of p53 functions in a patient with a 283H TP53 germ-line mutation: evidence for a precursor lesion. Cancer Research. 62: 2897-905. PMID 12019170  0.441
2002 Mabjeesh NJ, Post DE, Willard MT, Kaur B, Van Meir EG, Simons JW, Zhong H. Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells. Cancer Research. 62: 2478-82. PMID 11980636  0.458
2002 Brat DJ, Castellano-Sanchez A, Kaur B, Van Meir EG. Genetic and biologic progression in astrocytomas and their relation to angiogenic dysregulation. Advances in Anatomic Pathology. 9: 24-36. PMID 11756757 DOI: 10.1097/00125480-200201000-00004  0.472
1996 Van Meir EG. Cytokines and tumors of the central nervous system. Glia. 15: 264-88. PMID 8586463 DOI: 10.1002/glia.440150308  0.349
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