Baljit S. Khakh - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
General Biophysics, Neurobiology Biology, Cell Biology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Chai H, Diaz-Castro B, Shigetomi E, Monte E, Octeau JC, Yu X, Cohn W, Rajendran PS, Vondriska TM, Whitelegge JP, Coppola G, Khakh BS. Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence. Neuron. PMID 28712653 DOI: 10.1016/j.neuron.2017.06.029  0.6
2016 Xu J, Bernstein AM, Wong A, Lu XH, Khoja S, Yang XW, Davies DL, Micevych P, Sofroniew MV, Khakh BS. P2X4 Receptor Reporter Mice: Sparse Brain Expression and Feeding-Related Presynaptic Facilitation in the Arcuate Nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8902-20. PMID 27559172 DOI: 10.1523/JNEUROSCI.1496-16.2016  0.36
2016 Anderson MA, Burda JE, Ren Y, Ao Y, O'Shea TM, Kawaguchi R, Coppola G, Khakh BS, Deming TJ, Sofroniew MV. Astrocyte scar formation aids central nervous system axon regeneration. Nature. PMID 27027288 DOI: 10.1038/nature17623  0.36
2016 Jiang R, Diaz-Castro B, Looger LL, Khakh BS. Dysfunctional Calcium and Glutamate Signaling in Striatal Astrocytes from Huntington's Disease Model Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3453-70. PMID 27013675 DOI: 10.1523/JNEUROSCI.3693-15.2016  0.36
2016 Akassoglou K, Agalliu D, Chang CJ, Davalos D, Grutzendler J, Hillman EM, Khakh BS, Kleinfeld D, McGavern DB, Nelson SJ, Zlokovic BV. Neurovascular and Immuno-Imaging: From Mechanisms to Therapies. Proceedings of the Inaugural Symposium. Frontiers in Neuroscience. 10: 46. PMID 26941593 DOI: 10.3389/fnins.2016.00046  0.36
2016 Shigetomi E, Patel S, Khakh BS. Probing the Complexities of Astrocyte Calcium Signaling. Trends in Cell Biology. 26: 300-12. PMID 26896246 DOI: 10.1016/j.tcb.2016.01.003  0.6
2015 Olsen ML, Khakh BS, Skatchkov SN, Zhou M, Lee CJ, Rouach N. New Insights on Astrocyte Ion Channels: Critical for Homeostasis and Neuron-Glia Signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13827-35. PMID 26468182 DOI: 10.1523/JNEUROSCI.2603-15.2015  0.36
2015 Khakh BS, Sofroniew MV. Diversity of astrocyte functions and phenotypes in neural circuits. Nature Neuroscience. 18: 942-52. PMID 26108722 DOI: 10.1038/nn.4043  0.36
2015 Srinivasan R, Huang BS, Venugopal S, Johnston AD, Chai H, Zeng H, Golshani P, Khakh BS. Ca(2+) signaling in astrocytes from Ip3r2(-/-) mice in brain slices and during startle responses in vivo. Nature Neuroscience. 18: 708-17. PMID 25894291 DOI: 10.1038/nn.4001  0.36
2015 Khakh BS, McCarthy KD. Astrocyte calcium signaling: from observations to functions and the challenges therein. Cold Spring Harbor Perspectives in Biology. 7: a020404. PMID 25605709 DOI: 10.1101/cshperspect.a020404  0.36
2014 Jiang R, Haustein MD, Sofroniew MV, Khakh BS. Imaging intracellular Ca²⁺ signals in striatal astrocytes from adult mice using genetically-encoded calcium indicators. Journal of Visualized Experiments : Jove. e51972. PMID 25490346 DOI: 10.3791/51972  0.36
2014 Burnstock G, Nistri A, Khakh BS, Giniatullin R. ATP-gated P2X receptors in health and disease. Frontiers in Cellular Neuroscience. 8: 204. PMID 25104924 DOI: 10.3389/fncel.2014.00204  0.36
2014 Xu J, Chai H, Ehinger K, Egan TM, Srinivasan R, Frick M, Khakh BS. Imaging P2X4 receptor subcellular distribution, trafficking, and regulation using P2X4-pHluorin. The Journal of General Physiology. 144: 81-104. PMID 24935743 DOI: 10.1085/jgp.201411169  0.36
2014 Khakh BS, Sofroniew MV. Astrocytes and Huntington's disease. Acs Chemical Neuroscience. 5: 494-6. PMID 24842291 DOI: 10.1021/cn500100r  0.36
2014 Haustein MD, Kracun S, Lu XH, Shih T, Jackson-Weaver O, Tong X, Xu J, Yang XW, O'Dell TJ, Marvin JS, Ellisman MH, Bushong EA, Looger LL, Khakh BS. Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway. Neuron. 82: 413-29. PMID 24742463 DOI: 10.1016/j.neuron.2014.02.041  0.36
2014 Gray EE, Guglietta R, Khakh BS, O'Dell TJ. Inhibitory interactions between phosphorylation sites in the C terminus of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor GluA1 subunits. The Journal of Biological Chemistry. 289: 14600-11. PMID 24706758 DOI: 10.1074/jbc.M114.553537  0.36
2014 Tong X, Ao Y, Faas GC, Nwaobi SE, Xu J, Haustein MD, Anderson MA, Mody I, Olsen ML, Sofroniew MV, Khakh BS. Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice. Nature Neuroscience. 17: 694-703. PMID 24686787 DOI: 10.1038/nn.3691  0.36
2014 Zhang S, Anderson MA, Ao Y, Khakh BS, Fan J, Deming TJ, Sofroniew MV. Tunable diblock copolypeptide hydrogel depots for local delivery of hydrophobic molecules in healthy and injured central nervous system. Biomaterials. 35: 1989-2000. PMID 24314556 DOI: 10.1016/j.biomaterials.2013.11.005  0.36
2013 Shigetomi E, Jackson-Weaver O, Huckstepp RT, O'Dell TJ, Khakh BS. TRPA1 channels are regulators of astrocyte basal calcium levels and long-term potentiation via constitutive D-serine release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10143-53. PMID 23761909 DOI: 10.1523/JNEUROSCI.5779-12.2013  0.36
2013 Housley GD, Morton-Jones R, Vlajkovic SM, Telang RS, Paramananthasivam V, Tadros SF, Wong AC, Froud KE, Cederholm JM, Sivakumaran Y, Snguanwongchai P, Khakh BS, Cockayne DA, Thorne PR, Ryan AF. ATP-gated ion channels mediate adaptation to elevated sound levels. Proceedings of the National Academy of Sciences of the United States of America. 110: 7494-9. PMID 23592720 DOI: 10.1073/pnas.1222295110  0.36
2013 Shigetomi E, Bushong EA, Haustein MD, Tong X, Jackson-Weaver O, Kracun S, Xu J, Sofroniew MV, Ellisman MH, Khakh BS. Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses. The Journal of General Physiology. 141: 633-47. PMID 23589582 DOI: 10.1085/jgp.201210949  0.36
2013 Tong X, Shigetomi E, Looger LL, Khakh BS. Genetically encoded calcium indicators and astrocyte calcium microdomains. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 19: 274-91. PMID 23264008 DOI: 10.1177/1073858412468794  0.36
2012 Hamby ME, Coppola G, Ao Y, Geschwind DH, Khakh BS, Sofroniew MV. Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14489-510. PMID 23077035 DOI: 10.1523/JNEUROSCI.1256-12.2012  0.36
2012 Khakh BS, North RA. Neuromodulation by extracellular ATP and P2X receptors in the CNS. Neuron. 76: 51-69. PMID 23040806 DOI: 10.1016/j.neuron.2012.09.024  0.36
2012 Akerboom J, Chen TW, Wardill TJ, Tian L, Marvin JS, Mutlu S, Calderón NC, Esposti F, Borghuis BG, Sun XR, Gordus A, Orger MB, Portugues R, Engert F, Macklin JJ, ... ... Khakh BS, et al. Optimization of a GCaMP calcium indicator for neural activity imaging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13819-40. PMID 23035093 DOI: 10.1523/JNEUROSCI.2601-12.2012  0.36
2012 Shigetomi E, Tong X, Kwan KY, Corey DP, Khakh BS. TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3. Nature Neuroscience. 15: 70-80. PMID 22158513 DOI: 10.1038/nn.3000  0.36
2011 Richler E, Shigetomi E, Khakh BS. Neuronal P2X2 receptors are mobile ATP sensors that explore the plasma membrane when activated. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16716-30. PMID 22090499 DOI: 10.1523/JNEUROSCI.3362-11.2011  0.6
2011 Samways DS, Khakh BS, Dutertre S, Egan TM. Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors). Proceedings of the National Academy of Sciences of the United States of America. 108: 13800-5. PMID 21808018 DOI: 10.1073/pnas.1017550108  0.36
2011 Reeves AM, Shigetomi E, Khakh BS. Bulk loading of calcium indicator dyes to study astrocyte physiology: key limitations and improvements using morphological maps. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9353-8. PMID 21697385 DOI: 10.1523/JNEUROSCI.0127-11.2011  0.6
2010 Shigetomi E, Kracun S, Khakh BS. Monitoring astrocyte calcium microdomains with improved membrane targeted GCaMP reporters. Neuron Glia Biology. 6: 183-91. PMID 21205365 DOI: 10.1017/S1740925X10000219  0.6
2010 Shigetomi E, Kracun S, Sofroniew MV, Khakh BS. A genetically targeted optical sensor to monitor calcium signals in astrocyte processes. Nature Neuroscience. 13: 759-66. PMID 20495558 DOI: 10.1038/nn.2557  0.36
2010 Toulme E, Garcia A, Samways D, Egan TM, Carson MJ, Khakh BS. P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin. The Journal of General Physiology. 135: 333-53. PMID 20231374 DOI: 10.1085/jgp.200910336  0.36
2009 Khakh BS, Burnstock G. The double life of ATP. Scientific American. 301: 84-90, 92. PMID 20058644 DOI: 10.1038/scientificamerican1209-84  0.36
2009 Singh H, Warburton S, Vondriska TM, Khakh BS. Proteomics to identify proteins interacting with P2X2 ligand-gated cation channels. Journal of Visualized Experiments : Jove. PMID 19455095 DOI: 10.3791/1178  0.36
2009 Shigetomi E, Khakh BS. Measuring near plasma membrane and global intracellular calcium dynamics in astrocytes. Journal of Visualized Experiments : Jove. PMID 19396060 DOI: 10.3791/1142  0.6
2008 Chaumont S, Compan V, Toulme E, Richler E, Housley GD, Rassendren F, Khakh BS. Regulation of P2X2 receptors by the neuronal calcium sensor VILIP1. Science Signaling. 1: ra8. PMID 18922787 DOI: 10.1126/scisignal.1162329  0.36
2008 Samways DS, Khakh BS, Egan TM. Tunable calcium current through TRPV1 receptor channels. The Journal of Biological Chemistry. 283: 31274-8. PMID 18775990 DOI: 10.1074/jbc.C800131200  0.36
2008 Chaumont S, Khakh BS. Patch-clamp coordinated spectroscopy shows P2X2 receptor permeability dynamics require cytosolic domain rearrangements but not Panx-1 channels. Proceedings of the National Academy of Sciences of the United States of America. 105: 12063-8. PMID 18689682 DOI: 10.1073/pnas.0803008105  0.36
2008 Young MT, Fisher JA, Fountain SJ, Ford RC, North RA, Khakh BS. Molecular shape, architecture, and size of P2X4 receptors determined using fluorescence resonance energy transfer and electron microscopy. The Journal of Biological Chemistry. 283: 26241-51. PMID 18635539 DOI: 10.1074/jbc.M804458200  0.36
2008 Shigetomi E, Bowser DN, Sofroniew MV, Khakh BS. Two forms of astrocyte calcium excitability have distinct effects on NMDA receptor-mediated slow inward currents in pyramidal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6659-63. PMID 18579739 DOI: 10.1523/JNEUROSCI.1717-08.2008  0.36
2008 Richler E, Chaumont S, Shigetomi E, Sagasti A, Khakh BS. Tracking transmitter-gated P2X cation channel activation in vitro and in vivo. Nature Methods. 5: 87-93. PMID 18084300 DOI: 10.1038/nmeth1144  0.36
2005 Khakh BS, Fisher JA, Nashmi R, Bowser DN, Lester HA. An angstrom scale interaction between plasma membrane ATP-gated P2X2 and alpha4beta2 nicotinic channels measured with fluorescence resonance energy transfer and total internal reflection fluorescence microscopy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6911-20. PMID 16033901 DOI: 10.1523/JNEUROSCI.0561-05.2005  0.36
2005 Khakh BS, Egan TM. Contribution of transmembrane regions to ATP-gated P2X2 channel permeability dynamics. The Journal of Biological Chemistry. 280: 6118-29. PMID 15556949 DOI: 10.1074/jbc.M411324200  0.36
2004 Fisher JA, Girdler G, Khakh BS. Time-resolved measurement of state-specific P2X2 ion channel cytosolic gating motions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10475-87. PMID 15548662 DOI: 10.1523/JNEUROSCI.3250-04.2004  0.36
2004 Egan TM, Khakh BS. Contribution of calcium ions to P2X channel responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3413-20. PMID 15056721 DOI: 10.1523/JNEUROSCI.5429-03.2004  0.36
2004 Girdler G, Khakh BS. ATP-gated P2X channels. Current Biology : Cb. 14: R6. PMID 14711422  0.36
2002 Eickhorst AN, Berson A, Cockayne D, Lester HA, Khakh BS. Control of P2X(2) channel permeability by the cytosolic domain. The Journal of General Physiology. 120: 119-31. PMID 12149275 DOI: 10.1085/jgp.20028535  0.36
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