| Year |
Citation |
Score |
| 2022 |
Kalmode HP, Podsiadly I, Kabra A, Boulton A, Reddy P, Gao Y, Li C, Bushweller JH. Small-Molecule Inhibitors of the MLL1 CXXC Domain, an Epigenetic Reader of DNA Methylation. Acs Medicinal Chemistry Letters. 13: 1363-1369. PMID 35978680 DOI: 10.1021/acsmedchemlett.2c00198 |
0.433 |
|
| 2022 |
Kim KB, Kabra A, Kim DW, Xue Y, Huang Y, Hou PC, Zhou Y, Miranda LJ, Park JI, Shi X, Bender TP, Bushweller JH, Park KS. KIX domain determines a selective tumor-promoting role for EP300 and its vulnerability in small cell lung cancer. Science Advances. 8: eabl4618. PMID 35171684 DOI: 10.1126/sciadv.abl4618 |
0.637 |
|
| 2021 |
Kabra A, Bushweller J. The intrinsically disordered proteins MLLT3 (AF9) and MLLT1 (ENL) - multimodal transcriptional switches with roles in normal hematopoiesis, MLL fusion leukemia, and kidney cancer. Journal of Molecular Biology. 167117. PMID 34174329 DOI: 10.1016/j.jmb.2021.167117 |
0.383 |
|
| 2020 |
Schmidt CR, Achille NJ, Kuntimaddi A, Boulton AM, Leach BI, Zhang S, Zeleznik-Le NJ, Bushweller JH. BCOR Binding to MLL-AF9 Is Essential for Leukemia via Altered EYA1, SIX, and MYC Activity. Blood Cancer Discovery. 1: 162-177. PMID 32954361 DOI: 10.1158/2643-3230.BCD-20-0036 |
0.759 |
|
| 2019 |
Deltcheva E, Wray J, James C, Boiers C, Chettri JB, Richardson S, Illendula A, Bushweller J, Nimmo R, Enver T. EXPLOITING CBF DEPENDENCY IN B-ACUTE LYMPHOBLASTIC LEUKAEMIA AS A NOVEL THERAPEUTIC APPROACH Experimental Hematology. 76: S63. DOI: 10.1016/J.Exphem.2019.06.348 |
0.323 |
|
| 2018 |
Zhou Y, Bushweller JH. Solution structure and elevator mechanism of the membrane electron transporter CcdA. Nature Structural & Molecular Biology. PMID 29379172 DOI: 10.1038/S41594-018-0022-Z |
0.515 |
|
| 2018 |
Schmidt C, Kuntimaddi A, Leach B, Bushweller J. Solution NMR structure of BCoR in complex with AF9 (BCoR-AF9) Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb6B7G/Pdb |
0.699 |
|
| 2018 |
Bushweller JH, Schmidt C, Achille N, Kuntimaddi A, Boulton A, Leach B, Zhang S, Zeleznik-Le NJ. Direct Binding of BCOR, but Not CBX8, to MLL-AF9 Is Essential for MLL-AF9 Leukemia Via Regulation of the EYA1/SIX1 Gene Network Blood. 132: 1316-1316. DOI: 10.1182/Blood-2018-99-111388 |
0.759 |
|
| 2017 |
Oo ZM, Illendula A, Grembecka J, Schmidt C, Zhou Y, Esain V, Kwan W, Frost I, North TE, Rajewski RA, Speck NA, Bushweller JH. A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cells. Leukemia & Lymphoma. 1-13. PMID 29249175 DOI: 10.1080/10428194.2017.1410882 |
0.622 |
|
| 2017 |
Illendula A, Gilmour J, Grembecka J, Tirumala VSS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, ... ... Bushweller JH, et al. Corrigendum to: "Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers" [EBioMedicine 8 (2016) 117-131]. Ebiomedicine. PMID 29104075 DOI: 10.1016/J.Ebiom.2017.10.029 |
0.57 |
|
| 2017 |
Tahirov TH, Bushweller J. Structure and Biophysics of CBFβ/RUNX and Its Translocation Products. Advances in Experimental Medicine and Biology. 962: 21-31. PMID 28299648 DOI: 10.1007/978-981-10-3233-2_2 |
0.482 |
|
| 2016 |
Illendula A, Gilmour J, Grembecka J, Tirumala VS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, ... ... Bushweller JH, et al. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. Ebiomedicine. 8: 117-131. PMID 27428424 DOI: 10.1016/J.Ebiom.2016.04.032 |
0.63 |
|
| 2016 |
Bushweller J. Abstract SY15-03: Drugging “undruggable” transcription factor drivers in cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Sy15-03 |
0.357 |
|
| 2016 |
Illendula A, Gilmour J, Grembecka J, Tirumala VSS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, ... ... Bushweller JH, et al. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers Ebiomedicine. DOI: 10.1016/j.ebiom.2016.04.032 |
0.63 |
|
| 2015 |
Xiao S, Brannon MK, Zhao X, Fread KI, Ellena JF, Bushweller JH, Finkielstein CV, Armstrong GS, Capelluto DG. Tom1 Modulates Binding of Tollip to Phosphatidylinositol 3-Phosphate via a Coupled Folding and Binding Mechanism. Structure (London, England : 1993). PMID 26320582 DOI: 10.1016/J.Str.2015.07.017 |
0.37 |
|
| 2015 |
Illendula A, Pulikkan JA, Zong H, Grembecka J, Xue L, Sen S, Zhou Y, Boulton A, Kuntimaddi A, Gao Y, Rajewski RA, Guzman ML, Castilla LH, Bushweller JH. Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice. Science (New York, N.Y.). 347: 779-84. PMID 25678665 DOI: 10.1126/Science.Aaa0314 |
0.621 |
|
| 2015 |
Xiao S, Brannon MK, Armstrong GS, Fread K, Ellena J, Bushweller JH, Finkielstein CV, Capelluto DG. Tom1 Modulates the Endosomal Function of Tollip via a Folding-Upon-Binding Mechanism Biophysical Journal. 108: 343a. DOI: 10.1016/J.Bpj.2014.11.1880 |
0.393 |
|
| 2015 |
Bushweller J, Kuntimaddi A, Thorpe J, Achille N, Lokken A, Singh R, Adli M, Zeleznik-Le N. Intrinsic Disorder, Epigenetics, and Leukemia - the MLL-AF9 SAGA Biophysical Journal. 108: 5a. DOI: 10.1016/J.Bpj.2014.11.045 |
0.502 |
|
| 2014 |
Lokken AA, Achille NJ, Chang MJ, Lin JJ, Kuntimaddi A, Leach BI, Malik B, Nesbit JB, Zhang S, Bushweller JH, Zeleznik-Le NJ, Hemenway CS. Importance of a specific amino acid pairing for murine MLL leukemias driven by MLLT1/3 or AFF1/4. Leukemia Research. 38: 1309-15. PMID 25282333 DOI: 10.1016/J.Leukres.2014.08.010 |
0.722 |
|
| 2014 |
Arora A, Abildgaard F, Bushweller J, Cierpicki T, Liang B, Tamm L. Chemical shifts and structural constraints of outer membrane protein A Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr19940 |
0.301 |
|
| 2013 |
Risner LE, Kuntimaddi A, Lokken AA, Achille NJ, Birch NW, Schoenfelt K, Bushweller JH, Zeleznik-Le NJ. Functional specificity of CpG DNA-binding CXXC domains in mixed lineage leukemia. The Journal of Biological Chemistry. 288: 29901-10. PMID 23990460 DOI: 10.1074/Jbc.M113.474858 |
0.418 |
|
| 2013 |
Regan MC, Horanyi PS, Pryor EE, Sarver JL, Cafiso DS, Bushweller JH. Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited. Proceedings of the National Academy of Sciences of the United States of America. 110: 13374-9. PMID 23898196 DOI: 10.1073/Pnas.1301726110 |
0.32 |
|
| 2013 |
Leach BI, Kuntimaddi A, Schmidt CR, Cierpicki T, Johnson SA, Bushweller JH. Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Structure (London, England : 1993). 21: 176-83. PMID 23260655 DOI: 10.1016/J.Str.2012.11.011 |
0.755 |
|
| 2013 |
Leach B, Lumba B, Chang M, Cierpicki T, Johnson S, Hemenway C, Bushweller J. Solution structure of the AF4-AF9 complex Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Lm0/Pdb |
0.697 |
|
| 2013 |
Kuntimaddi A, Lokken A, Zhang S, Thorpe J, Leach B, Lumba B, Hemenway CS, Adli M, Zeleznik-Le NJ, Bushweller JH. Structural and Functional Studies Of The Intrinsically Disordered Protein AF9 In MLL-AF9 Leukemia Blood. 122: 3762-3762. DOI: 10.1182/Blood.V122.21.3762.3762 |
0.767 |
|
| 2012 |
Bushweller JH, Illendula A, Pulikkan JA, Grembecka J, Bradley P, Zhou Y, Xue L, Gao Y, Castilla LH. A Small Molecule Inhibitor of the CBFβ-SMMHC/RUNX Interaction Attenuates Inv(16) Leukemia in Vivo Blood. 120: 286-286. DOI: 10.1182/Blood.V120.21.286.286 |
0.579 |
|
| 2011 |
Chen H, Ji F, Olman V, Mobley CK, Liu Y, Zhou Y, Bushweller JH, Prestegard JH, Xu Y. Optimal mutation sites for PRE data collection and membrane protein structure prediction. Structure (London, England : 1993). 19: 484-95. PMID 21481772 DOI: 10.1016/J.Str.2011.02.002 |
0.69 |
|
| 2011 |
Bushweller JH, Leach B, Chang M, Lumba B, Cierpicki T, Zeleznik-Le NJ, Hemenway CS. The Role of the Intrinsically Disordered and Multifunctional AF9 C-Terminal Domain in MLL-AF9 Leukemia, Blood. 118: 3464-3464. DOI: 10.1182/Blood.V118.21.3464.3464 |
0.749 |
|
| 2010 |
Früh V, Zhou Y, Chen D, Loch C, Ab E, Grinkova YN, Verheij H, Sligar SG, Bushweller JH, Siegal G. Application of fragment-based drug discovery to membrane proteins: identification of ligands of the integral membrane enzyme DsbB. Chemistry & Biology. 17: 881-91. PMID 20797617 DOI: 10.1016/J.Chembiol.2010.06.011 |
0.544 |
|
| 2010 |
Corpora T, Roudaia L, Oo ZM, Chen W, Manuylova E, Cai X, Chen MJ, Cierpicki T, Speck NA, Bushweller JH. Structure of the AML1-ETO NHR3-PKA(RIIα) complex and its contribution to AML1-ETO activity. Journal of Molecular Biology. 402: 560-77. PMID 20708017 DOI: 10.1016/J.Jmb.2010.08.007 |
0.808 |
|
| 2010 |
Park S, Osmers U, Raman G, Schwantes RH, Diaz MO, Bushweller JH. The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression . Biochemistry. 49: 6576-86. PMID 20677832 DOI: 10.1021/Bi1009387 |
0.373 |
|
| 2010 |
Kamikubo Y, Zhao L, Wunderlich M, Corpora T, Hyde RK, Paul TA, Kundu M, Garrett L, Compton S, Huang G, Wolff L, Ito Y, Bushweller J, Mulloy JC, Liu PP. Accelerated leukemogenesis by truncated CBF beta-SMMHC defective in high-affinity binding with RUNX1. Cancer Cell. 17: 455-68. PMID 20478528 DOI: 10.1016/J.Ccr.2010.03.022 |
0.794 |
|
| 2010 |
Cierpicki T, Risner LE, Grembecka J, Lukasik SM, Popovic R, Omonkowska M, Shultis DD, Zeleznik-Le NJ, Bushweller JH. Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia. Nature Structural & Molecular Biology. 17: 62-8. PMID 20010842 DOI: 10.1038/Nsmb.1714 |
0.808 |
|
| 2010 |
Park S, Bushweller J. Solution structure of the RRM domain of CYP33 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Kyx/Pdb |
0.361 |
|
| 2010 |
Risner LE, Kuntimaddi A, Bushweller JH, Zeleznik-Le NJ. DNMT1 Cxxc Domain Can Functionally Substitute In An MLL Fusion Protein Blood. 116: 4193-4193. DOI: 10.1182/Blood.V116.21.4193.4193 |
0.454 |
|
| 2009 |
Park S, Chen W, Cierpicki T, Tonelli M, Cai X, Speck NA, Bushweller JH. Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity. Blood. 113: 3558-67. PMID 19204326 DOI: 10.1182/Blood-2008-06-161307 |
0.376 |
|
| 2009 |
Roudaia L, Cheney MD, Manuylova E, Chen W, Morrow M, Park S, Lee CT, Kaur P, Williams O, Bushweller JH, Speck NA. CBFbeta is critical for AML1-ETO and TEL-AML1 activity. Blood. 113: 3070-9. PMID 19179469 DOI: 10.1182/Blood-2008-03-147207 |
0.4 |
|
| 2009 |
Risner L, Cierpicki T, Grembecka J, Lukasik SM, Popovic R, Shultis DS, Zeleznik-Le NJ, Bushweller JH. Structural Basis for MLL Cxxc Domain Protection against CpG DNA Methylation and the Essential Role of This Function in MLL-AF9 Leukemia. Blood. 114: 763-763. DOI: 10.1182/Blood.V114.22.763.763 |
0.798 |
|
| 2008 |
Zhou Y, Cierpicki T, Jimenez RH, Lukasik SM, Ellena JF, Cafiso DS, Kadokura H, Beckwith J, Bushweller JH. NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. Molecular Cell. 31: 896-908. PMID 18922471 DOI: 10.1016/J.Molcel.2008.08.028 |
0.768 |
|
| 2007 |
Gorczynski MJ, Grembecka J, Zhou Y, Kong Y, Roudaia L, Douvas MG, Newman M, Bielnicka I, Baber G, Corpora T, Shi J, Sridharan M, Lilien R, Donald BR, Speck NA, ... ... Bushweller JH, et al. Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbeta. Chemistry & Biology. 14: 1186-97. PMID 17961830 DOI: 10.1016/J.Chembiol.2007.09.006 |
0.799 |
|
| 2007 |
Liu Y, Chen W, Gaudet J, Cheney MD, Roudaia L, Cierpicki T, Klet RC, Hartman K, Laue TM, Speck NA, Bushweller JH. Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity. Cancer Cell. 11: 483-97. PMID 17560331 DOI: 10.1016/J.Ccr.2007.04.010 |
0.632 |
|
| 2007 |
Matheny CJ, Speck ME, Cushing PR, Zhou Y, Corpora T, Regan M, Newman M, Roudaia L, Speck CL, Gu TL, Griffey SM, Bushweller JH, Speck NA. Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles. The Embo Journal. 26: 1163-75. PMID 17290219 DOI: 10.1038/Sj.Emboj.7601568 |
0.788 |
|
| 2007 |
Douvas MG, Roudaiya L, Grembecka J, Speck N, Bushweller J. Development of Allosteric Inhibitors of the Interaction of AML1 and CBFβ for the Treatment of Leukemia. Blood. 110: 653-653. DOI: 10.1182/Blood.V110.11.653.653 |
0.311 |
|
| 2007 |
Grembecka JE, Graf K, Kong Y, Douvas M, Cierpicki T, Illendula A, Baber G, Bielnicka I, Roudaia L, Speck NA, Brown ML, Bushweller JH. Development of Small Molecule Inhibitors of the AML1-ETO and CBFβ-SMMHC Oncoproteins. Blood. 110: 1591-1591. DOI: 10.1182/Blood.V110.11.1591.1591 |
0.348 |
|
| 2007 |
Bushweller JH, Zhou Y, Cierpicki T. Solution NMR structure and dynamics of the integral membrane enzyme DsbB ‐ insights into periplasmic disulfide bond formation The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A148-B |
0.506 |
|
| 2006 |
Li Z, Lukasik SM, Liu Y, Grembecka J, Bielnicka I, Bushweller JH, Speck NA. A mutation in the S-switch region of the Runt domain alters the dynamics of an allosteric network responsible for CBFbeta regulation. Journal of Molecular Biology. 364: 1073-83. PMID 17059830 DOI: 10.1016/J.Jmb.2006.10.002 |
0.83 |
|
| 2006 |
Cierpicki T, Kim MH, Cooper DR, Derewenda U, Bushweller JH, Derewenda ZS. The DC-module of doublecortin: dynamics, domain boundaries, and functional implications. Proteins. 64: 874-82. PMID 16835924 DOI: 10.1002/prot.21068 |
0.335 |
|
| 2006 |
Liu Y, Cheney MD, Gaudet JJ, Chruszcz M, Lukasik SM, Sugiyama D, Lary J, Cole J, Dauter Z, Minor W, Speck NA, Bushweller JH. The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity. Cancer Cell. 9: 249-60. PMID 16616331 DOI: 10.1016/J.Ccr.2006.03.012 |
0.801 |
|
| 2006 |
Grembecka J, Cierpicki T, Devedjiev Y, Derewenda U, Kang BS, Bushweller JH, Derewenda ZS. The binding of the PDZ tandem of syntenin to target proteins. Biochemistry. 45: 3674-83. PMID 16533050 DOI: 10.1021/bi052225y |
0.383 |
|
| 2006 |
Lukasik SM, Cierpicki T, Borloz M, Grembecka J, Everett A, Bushweller JH. High resolution structure of the HDGF PWWP domain: a potential DNA binding domain. Protein Science : a Publication of the Protein Society. 15: 314-23. PMID 16384999 DOI: 10.1110/Ps.051751706 |
0.806 |
|
| 2005 |
Brautigan DL, Brown M, Grindrod S, Chinigo G, Kruszewski A, Lukasik SM, Bushweller JH, Horal M, Keller S, Tamura S, Heimark DB, Price J, Larner AN, Larner J. Allosteric activation of protein phosphatase 2C by D-chiro-inositol-galactosamine, a putative mediator mimetic of insulin action. Biochemistry. 44: 11067-73. PMID 16101290 DOI: 10.1021/Bi0508845 |
0.738 |
|
| 2005 |
Bushweller JH, Gorczynski MJ, Grembecka J, Newman M, Corpora T, Zhou Y, Kong Y, Jeon J, Liu PP, Brown ML. Development of Small Molecule Inhibitors of the CBFβ-SMMHC Oncoprotein. Blood. 106: 3359-3359. DOI: 10.1182/Blood.V106.11.3359.3359 |
0.805 |
|
| 2005 |
Cheney MD, Liu Y, Gaudet JJ, Chruszcz M, Lukasik SM, Sugiyama D, Lary J, Cole J, Dauter Z, Minor W, Speck NA, Bushweller JH. Structural and Functional Characterization of the NHR2 and Runt Domains of AML1/ETO. Blood. 106: 2854-2854. DOI: 10.1182/Blood.V106.11.2854.2854 |
0.83 |
|
| 2005 |
Bushweller JH, Lukasik SM, Speck NA. The CBFb-SMMHC Oncoprotein Inhibits Binding of the Runx1 Runt Domain to DNA. Blood. 106: 2709-2709. DOI: 10.1182/Blood.V106.11.2709.2709 |
0.821 |
|
| 2004 |
Yan J, Liu Y, Lukasik SM, Speck NA, Bushweller JH. CBFbeta allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium. Nature Structural & Molecular Biology. 11: 901-6. PMID 15322525 DOI: 10.1038/Nsmb819 |
0.814 |
|
| 2004 |
Matheny CJ, Corpora T, Speck ME, Gu T, Bushweller JH, Speck NA. Biochemical and In Vivo Characterization of Amino Acid Substitutions in the Runx1 (AML1) Runt Domain Found in FPD/AML, AML M0, and Cleidocranial Dysplasia (CCD) Patients. Blood. 104: 464-464. DOI: 10.1182/Blood.V104.11.464.464 |
0.82 |
|
| 2003 |
Everett AD, Bushweller J. Hepatoma derived growth factor is a nuclear targeted mitogen. Current Drug Targets. 4: 367-71. PMID 12816346 DOI: 10.2174/1389450033490975 |
0.305 |
|
| 2003 |
Zhang L, Li Z, Yan J, Pradhan P, Corpora T, Cheney MD, Bravo J, Warren AJ, Bushweller JH, Speck NA. Mutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunit. The Journal of Biological Chemistry. 278: 33097-104. PMID 12807883 DOI: 10.1074/Jbc.M303972200 |
0.818 |
|
| 2003 |
Li Z, Yan J, Matheny CJ, Corpora T, Bravo J, Warren AJ, Bushweller JH, Speck NA. Energetic contribution of residues in the Runx1 Runt domain to DNA binding. The Journal of Biological Chemistry. 278: 33088-96. PMID 12807882 DOI: 10.1074/Jbc.M303973200 |
0.826 |
|
| 2003 |
Zhang L, Lukasik SM, Speck NA, Bushweller JH. Structural and functional characterization of Runx1, CBF beta, and CBF beta-SMMHC. Blood Cells, Molecules & Diseases. 30: 147-56. PMID 12732176 DOI: 10.1016/S1079-9796(03)00022-6 |
0.796 |
|
| 2003 |
Kim MH, Cierpicki T, Derewenda U, Krowarsch D, Feng Y, Devedjiev Y, Dauter Z, Walsh CA, Otlewski J, Bushweller JH, Derewenda ZS. The DCX-domain tandems of doublecortin and doublecortin-like kinase. Nature Structural Biology. 10: 324-33. PMID 12692530 DOI: 10.1038/nsb918 |
0.389 |
|
| 2002 |
Lukasik SM, Zhang L, Corpora T, Tomanicek S, Li Y, Kundu M, Hartman K, Liu PP, Laue TM, Biltonen RL, Speck NA, Bushweller JH. Altered affinity of CBF beta-SMMHC for Runx1 explains its role in leukemogenesis. Nature Structural Biology. 9: 674-9. PMID 12172539 DOI: 10.1038/Nsb831 |
0.792 |
|
| 2002 |
Yan J, Corpora T, Pradhan P, Bushweller JH. MQ-hCN-based pulse sequences for the measurement of 13C1'-1H1', 13C1'-15N, 1H1'-15N, 13C1'-13C2', 1H1'-13C2',13C6/8-1H6/8, 13C6/8-15N, 1H6/8-15N, 13C6-13C5, 1H6-13C5 dipolar couplings in 13C, 15N-labeled DNA (and RNA). Journal of Biomolecular Nmr. 22: 9-20. PMID 11885985 DOI: 10.1023/A:1013876105589 |
0.747 |
|
| 2001 |
Bushweller JH. CBF--a biophysical perspective. Seminars in Cell & Developmental Biology. 11: 377-82. PMID 11105902 DOI: 10.1006/scdb.2000.0182 |
0.444 |
|
| 2000 |
Tang YY, Shi J, Zhang L, Davis A, Bravo J, Warren AJ, Speck NA, Bushweller JH. Energetic and functional contribution of residues in the core binding factor beta (CBFbeta ) subunit to heterodimerization with CBFalpha. The Journal of Biological Chemistry. 275: 39579-88. PMID 10984496 DOI: 10.1074/Jbc.M007350200 |
0.433 |
|
| 2000 |
Tang YY, Crute BE, Kelley JJ, Huang X, Yan J, Shi J, Hartman KL, Laue TM, Speck NA, Bushweller JH. Biophysical characterization of interactions between the core binding factor alpha and beta subunits and DNA. Febs Letters. 470: 167-72. PMID 10734228 DOI: 10.1016/S0014-5793(00)01312-0 |
0.372 |
|
| 1999 |
Berardi MJ, Sun C, Zehr M, Abildgaard F, Peng J, Speck NA, Bushweller JH. The Ig fold of the core binding factor α Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains Structure. 7: 1247-1256. PMID 10545320 DOI: 10.1016/S0969-2126(00)80058-1 |
0.408 |
|
| 1999 |
Huang X, Peng JW, Speck NA, Bushweller JH. Solution structure of core binding factor beta and map of the CBF alpha binding site. Nature Structural Biology. 6: 624-7. PMID 10404216 DOI: 10.1038/10670 |
0.335 |
|
| 1998 |
Huang X, Crute BE, Sun C, Tang YY, Kelley JJ, Lewis AF, Hartman KL, Laue TM, Speck NA, Bushweller JH. Overexpression, purification, and biophysical characterization of the heterodimerization domain of the core-binding factor beta subunit. The Journal of Biological Chemistry. 273: 2480-7. PMID 9442100 DOI: 10.1074/Jbc.273.4.2480 |
0.368 |
|
| 1998 |
Huang X, Speck N, Bushweller J. Complete Heteronuclear NMR Resonance Assignments, Secondary Structure, and Mapping of Core Binding Factor a Binding Site for Core Binding Factor b (1-141) Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr4092 |
0.388 |
|
| 1997 |
Wang Q, Stacy T, Miller JD, Lewis AF, Gu TL, Huang X, Bushweller JH, Bories JC, Alt FW, Ryan G, Liu PP, Wynshaw-Boris A, Binder M, Marín-Padilla M, Sharpe AH, et al. The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo. Cell. 87: 697-708. PMID 8929538 DOI: 10.1016/S0092-8674(00)81389-6 |
0.358 |
|
| 1996 |
Crute BE, Lewis AF, Wu Z, Bushweller JH, Speck NA. Biochemical and biophysical properties of the core-binding factor alpha2 (AML1) DNA-binding domain. The Journal of Biological Chemistry. 271: 26251-60. PMID 8824275 DOI: 10.1074/Jbc.271.42.26251 |
0.433 |
|
| 1994 |
Bushweller JH, Holmgren A, Wüthrich K. Biosynthetic 15N and 13C isotope labelling of glutathione in the mixed disulfide with Escherichia coli glutaredoxin documented by sequence-specific NMR assignments. European Journal of Biochemistry. 218: 327-34. PMID 8269921 DOI: 10.1111/J.1432-1033.1993.Tb18381.X |
0.354 |
|
| 1994 |
Bushweller JH, Billeter M, Holmgren A, Wüthrich K. The nuclear magnetic resonance solution structure of the mixed disulfide between Escherichia coli glutaredoxin(C14S) and glutathione. Journal of Molecular Biology. 235: 1585-97. PMID 8107093 DOI: 10.1006/Jmbi.1994.1108 |
0.438 |
|
| 1994 |
Szyperski T, Wider G, Bushweller JH, Wuethrich K. Reduced dimensionality in triple-resonance NMR experiments. [Erratum to document cited in CA119(18):194184g] Journal of the American Chemical Society. 116: 1601-1601. DOI: 10.1021/Ja00083A069 |
0.409 |
|
| 1993 |
Szyperski T, Wider G, Bushweller JH, Wüthrich K. 3D 13C-15N-heteronuclear two-spin coherence spectroscopy for polypeptide backbone assignments in 13C-15N-double-labeled proteins. Journal of Biomolecular Nmr. 3: 127-32. PMID 8448432 DOI: 10.1007/Bf00242481 |
0.559 |
|
| 1993 |
Xia TH, Bushweller JH, Sodano P, Billeter M, Björnberg O, Holmgren A, Wüthrich K. NMR structure of oxidized Escherichia coli glutaredoxin: comparison with reduced E. coli glutaredoxin and functionally related proteins. Protein Science : a Publication of the Protein Society. 1: 310-21. PMID 1304339 DOI: 10.1002/Pro.5560010302 |
0.422 |
|
| 1993 |
Szyperski T, Wider G, Bushweller JH, Wuethrich K. Reduced dimensionality in triple-resonance NMR experiments Journal of the American Chemical Society. 115: 9307-9308. DOI: 10.1021/Ja00073A064 |
0.422 |
|
| 1992 |
Bushweller JH, Aslund F, Wüthrich K, Holmgren A. Structural and functional characterization of the mutant Escherichia coli glutaredoxin (C14----S) and its mixed disulfide with glutathione. Biochemistry. 31: 9288-93. PMID 1390715 DOI: 10.1021/bi00153a023 |
0.444 |
|
| 1991 |
Sodano P, Xia TH, Bushweller JH, Björnberg O, Holmgren A, Billeter M, Wüthrich K. Sequence-specific 1H n.m.r. assignments and determination of the three-dimensional structure of reduced Escherichia coli glutaredoxin. Journal of Molecular Biology. 221: 1311-24. PMID 1942053 DOI: 10.1016/0022-2836(91)90935-Y |
0.437 |
|
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