Robert A. Mooney - Publications

Affiliations: 
University of Rochester, Rochester, NY 
Area:
Biochemistry, Pathology

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Farnsworth CW, Schott EM, Benvie A, Kates SL, Schwarz EM, Gill SR, Zuscik MJ, Mooney RA. Exacerbated Foot Infections in Obese/Diabetic Mice Are Associated with Impaired Germinal Center Reactions, Ig Class Switching, and Humoral Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 29858265 DOI: 10.4049/Jimmunol.1800253  0.367
2018 Schott EM, Farnsworth CW, Grier A, Lillis JA, Soniwala S, Dadourian GH, Bell RD, Doolittle ML, Villani DA, Awad H, Ketz JP, Kamal F, Ackert-Bicknell C, Ashton JM, Gill SR, ... Mooney RA, et al. Targeting the gut microbiome to treat the osteoarthritis of obesity. Jci Insight. 3. PMID 29669931 DOI: 10.1172/Jci.Insight.95997  0.324
2018 Schott E, Lillis J, Farnsworth C, Villani D, Ketz J, Ashton J, Gill S, Zuscik M, Mooney R. Early synovial B-cell infiltration as a candidate mechanism of pathogenesis in the OA of obesity Osteoarthritis and Cartilage. 26: S14. DOI: 10.1016/J.Joca.2018.02.045  0.302
2017 Farnsworth CW, Schott EM, Benvie AM, Zukoski J, Kates SL, Schwarz EM, Gill SR, Zuscik MJ, Mooney RA. Obesity/type 2 diabetes increases inflammation, periosteal reactive bone formation and osteolysis during Staphylococcus aureus implant-associated bone infection. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 29227579 DOI: 10.1002/Jor.23831  0.342
2017 Dar QA, Schott EM, Catheline SE, Maynard RD, Liu Z, Kamal F, Farnsworth CW, Ketz JP, Mooney RA, Hilton MJ, Jonason JH, Prawitt J, Zuscik MJ. Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis. Plos One. 12: e0174705. PMID 28384173 DOI: 10.1371/Journal.Pone.0174705  0.304
2017 Farnsworth CW, Schott EM, Jensen SE, Zukoski J, Benvie AM, Refaai MA, Kates SL, Schwarz EM, Zuscik MJ, Gill SR, Mooney RA. Adaptive upregulation of Clumping Factor A (ClfA) by S. aureus in the obese, type 2 diabetic host mediates increased virulence. Infection and Immunity. PMID 28320836 DOI: 10.1128/Iai.01005-16  0.351
2015 Hamada D, Maynard R, Schott E, Drinkwater CJ, Ketz JP, Kates SL, Jonason JH, Hilton MJ, Zuscik MJ, Mooney RA. Insulin Suppresses TNF-dependent Early Osteoarthritic Changes Associated with Obesity and Type 2 Diabetes. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26713606 DOI: 10.1002/Art.39561  0.489
2015 Farnsworth CW, Shehatou CT, Maynard R, Nishitani K, Kates SL, Zuscik MJ, Schwarz EM, Daiss JL, Mooney RA. A Humoral Immune Defect Distinguishes the Response to Staphylococcus aureus Infections in Mice with Obesity and Type 2 Diabetes from That in Mice with Type 1 Diabetes. Infection and Immunity. 83: 2264-74. PMID 25802056 DOI: 10.1128/Iai.03074-14  0.339
2015 Shu L, Beier E, Sheu T, Zhang H, Zuscik MJ, Puzas EJ, Boyce BF, Mooney RA, Xing L. High-fat diet causes bone loss in young mice by promoting osteoclastogenesis through alteration of the bone marrow environment. Calcified Tissue International. 96: 313-23. PMID 25673503 DOI: 10.1007/S00223-015-9954-Z  0.303
2014 David MA, Jones KH, Inzana JA, Zuscik MJ, Awad HA, Mooney RA. Tendon repair is compromised in a high fat diet-induced mouse model of obesity and type 2 diabetes. Plos One. 9: e91234. PMID 24658034 DOI: 10.1371/Journal.Pone.0091234  0.325
2014 Hamada D, Maynard R, Fransworth C, Kates S, Hilton M, Zuscik M, Mooney R. Insulin selectively suppresses TNFα/IL-1β-induced catabolic enzymes in Ostezoarthritic fibroblast-like synovziocytes Osteoarthritis and Cartilage. 22: S451-S452. DOI: 10.1016/J.Joca.2014.02.856  0.48
2014 Mooney R, Hamada D, Maynard R, Kates S, Zuscik M. TNFα is a critical mediator of synovial hyperplasia and osteophyte formation in high fat-fed mice Osteoarthritis and Cartilage. 22: S337. DOI: 10.1016/J.Joca.2014.02.624  0.343
2013 Inzana JA, Kung M, Shu L, Hamada D, Xing LP, Zuscik MJ, Awad HA, Mooney RA. Immature mice are more susceptible to the detrimental effects of high fat diet on cancellous bone in the distal femur. Bone. 57: 174-83. PMID 23954757 DOI: 10.1016/J.Bone.2013.08.003  0.328
2011 Mooney RA, Sampson ER, Lerea J, Rosier RN, Zuscik MJ. High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury. Arthritis Research & Therapy. 13: R198. PMID 22152451 DOI: 10.1186/Ar3529  0.308
2011 Clementi AH, Gaudy AM, Zimmers TA, Koniaris LG, Mooney RA. Deletion of interleukin-6 improves pyruvate tolerance without altering hepatic insulin signaling in the leptin receptor-deficient mouse. Metabolism: Clinical and Experimental. 60: 1610-9. PMID 21632071 DOI: 10.1016/J.Metabol.2011.04.004  0.747
2010 Gaudy AM, Clementi AH, Campbell JS, Smrcka AV, Mooney RA. Suppressor of cytokine signaling-3 is a glucagon-inducible inhibitor of PKA activity and gluconeogenic gene expression in hepatocytes. The Journal of Biological Chemistry. 285: 41356-65. PMID 20978125 DOI: 10.1074/Jbc.M110.159111  0.705
2010 Galloway CA, Ashton J, Sparks JD, Mooney RA, Smith HC. Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes. Biochimica Et Biophysica Acta. 1802: 976-85. PMID 20541607 DOI: 10.1016/J.Bbadis.2010.06.003  0.503
2009 Clementi AH, Gaudy AM, van Rooijen N, Pierce RH, Mooney RA. Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling. Biochimica Et Biophysica Acta. 1792: 1062-72. PMID 19699298 DOI: 10.1016/J.Bbadis.2009.08.007  0.749
2007 Mooney RA. Counterpoint: Interleukin-6 does not have a beneficial role in insulin sensitivity and glucose homeostasis. Journal of Applied Physiology (Bethesda, Md. : 1985). 102: 816-8; discussion 81. PMID 17284655 DOI: 10.1152/Japplphysiol.01208A.2006  0.491
2006 Chagnon MJ, Elchebly M, Uetani N, Dombrowski L, Cheng A, Mooney RA, Marette A, Tremblay ML. Altered glucose homeostasis in mice lacking the receptor protein tyrosine phosphatase sigma. Canadian Journal of Physiology and Pharmacology. 84: 755-63. PMID 16998539 DOI: 10.1139/y06-020  0.458
2005 Klover PJ, Clementi AH, Mooney RA. Interleukin-6 depletion selectively improves hepatic insulin action in obesity. Endocrinology. 146: 3417-27. PMID 15845623 DOI: 10.1210/En.2004-1468  0.792
2004 LeVea CM, Reeder JE, Mooney RA. EGF-dependent cell cycle progression is controlled by density-dependent regulation of Akt activation Experimental Cell Research. 297: 272-284. PMID 15194442 DOI: 10.1016/J.Yexcr.2004.03.026  0.329
2004 Klover PJ, Mooney RA. Hepatocytes: critical for glucose homeostasis. The International Journal of Biochemistry & Cell Biology. 36: 753-8. PMID 15061128 DOI: 10.1016/J.Biocel.2003.10.002  0.496
2003 Klover PJ, Zimmers TA, Koniaris LG, Mooney RA. Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice. Diabetes. 52: 2784-9. PMID 14578297 DOI: 10.2337/Diabetes.52.11.2784  0.623
2003 Mooney RA, LeVea CM. The leukocyte common antigen-related protein LAR: candidate PTP for inhibitory targeting. Current Topics in Medicinal Chemistry. 3: 809-19. PMID 12678846 DOI: 10.2174/1568026033452294  0.437
2003 Senn JJ, Klover PJ, Nowak IA, Zimmers TA, Koniaris LG, Furlanetto RW, Mooney RA. Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes. The Journal of Biological Chemistry. 278: 13740-6. PMID 12560330 DOI: 10.1074/Jbc.M210689200  0.827
2002 Senn JJ, Klover PJ, Nowak IA, Mooney RA. Interleukin-6 induces cellular insulin resistance in hepatocytes. Diabetes. 51: 3391-9. PMID 12453891 DOI: 10.2337/Diabetes.51.12.3391  0.814
2002 Symons JR, LeVea CM, Mooney RA. Expression of the leucocyte common antigen-related (LAR) tyrosine phosphatase is regulated by cell density through functional E-cadherin complexes. The Biochemical Journal. 365: 513-9. PMID 12095414 DOI: 10.1042/Bj20020381  0.332
2001 Mooney RA, Senn J, Cameron S, Inamdar N, Boivin LM, Shang Y, Furlanetto RW. Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor: A potential mechanism for cytokine-mediated insulin resistance Journal of Biological Chemistry. 276: 25889-25893. PMID 11342531 DOI: 10.1074/Jbc.M010579200  0.808
1999 Bleyle LA, Peng Y, Ellis C, Mooney RA. Dissociation of PTPase levels from their modulation of insulin receptor signal transduction Cellular Signalling. 11: 719-725. PMID 10574326 DOI: 10.1016/S0898-6568(99)00043-1  0.514
1997 Phung TL, Mooney RA, Kulas DT, Sparks CE, Sparks JD. Suppression of the protein tyrosine phosphatase LAR reduces apolipoprotein B secretion by McA-RH7777 rat hepatoma cells Biochemical and Biophysical Research Communications. 237: 367-371. PMID 9268718 DOI: 10.1006/Bbrc.1997.7142  0.408
1997 Mooney RA, Kulas DT, Bleyle LA, Novak JS. The protein tyrosine phosphatase LAR has a major impact on insulin receptor dephosphorylation Biochemical and Biophysical Research Communications. 235: 709-712. PMID 9207225 DOI: 10.1006/Bbrc.1997.6889  0.496
1996 Kulas DT, Freund GG, Mooney RA. The transmembrane protein-tyrosine phosphatase CD45 is associated with decreased insulin receptor signaling Journal of Biological Chemistry. 271: 755-760. PMID 8557683 DOI: 10.1074/Jbc.271.2.755  0.435
1996 Kulas DT, Goldstein BJ, Mooney RA. The transmembrane protein-tyrosine phosphatase LAR modulates signaling by multiple receptor tyrosine kinases Journal of Biological Chemistry. 271: 748-754. PMID 8557682 DOI: 10.1074/Jbc.271.2.748  0.467
1995 Kulas DT, Zhang WR, Goldstein BJ, Furlanetto RW, Mooney RA. Insulin receptor signaling is augmented by antisense inhibition of the protein tyrosine phosphatase LAR Journal of Biological Chemistry. 270: 2435-2438. PMID 7852302 DOI: 10.1074/Jbc.270.6.2435  0.522
1995 Freund GG, Wittig JG, Mooney RA. The PI3-Kinase Serine Kinase Phosphorylates Its p85 Subunit and IRS-1 in PI3-Kinase/IRS-1 Complexes Biochemical and Biophysical Research Communications. 206: 272-278. PMID 7818531 DOI: 10.1006/Bbrc.1995.1038  0.393
1994 Way BA, Mooney RA. Differential effects of phosphotyrosine phosphatase expression on hormone-dependent and independent pp60c-src activity. Molecular and Cellular Biochemistry. 139: 167-75. PMID 7532275 DOI: 10.1007/Bf01081740  0.368
1992 Mooney RA, Bordwell KL. Insulin stimulates the tyrosine phosphorylation of a 61-kilodalton protein in rat adipocytes Endocrinology. 130: 1533-1538. PMID 1371454 DOI: 10.1210/Endo.130.3.1371454  0.421
1991 Mooney RA, Bordwell KL. Counter-regulation by insulin and isoprenaline of a prominent fat-associated phosphoprotein doublet in rat adipocytes Biochemical Journal. 274: 433-438. PMID 1848760 DOI: 10.1042/Bj2740433  0.427
1989 Mooney RA, Green DA. Insulin receptor dephosphorylation in permeabilized adipocytes is inhibitable by manganese and independent of receptor kinase activity. Biochemical and Biophysical Research Communications. 162: 1200-6. PMID 2475105 DOI: 10.1016/0006-291X(89)90801-2  0.454
1989 Mooney RA, Bordwell KL, Luhowskyj S, Casnellie JE. The insulin-like effect of vanadate on lipolysis in rat adipocytes is not accompanied by an insulin-like effect on tyrosine phosphorylation Endocrinology. 124: 422-429. PMID 2462493 DOI: 10.1210/Endo-124-1-422  0.46
1986 Mooney RA, Swicegood CL, Marx RB. Coupling of adenylate cyclase to lipolysis in permeabilized adipocytes: Direct evidence that an antilipolytic effect of insulin is independent of adenylate cyclase Endocrinology. 119: 2240-2248. PMID 3095104 DOI: 10.1210/Endo-119-5-2240  0.399
1983 Mooney RA, Ebersohl RD, McDonald JM. Novel approach to the study of the regulation of hormone-sensitive lipase in rat adipocytes. Permeabilization of cells with digitonin European Journal of Biochemistry. 136: 603-608. PMID 6315436 DOI: 10.1111/J.1432-1033.1983.Tb07783.X  0.372
1982 Mooney RA, Lane MD. Control of ketogenesis and fatty-acid synthesis at the mitochondrial branch-point for acetyl-CoA in the chick liver cell: Effect of adenosine 3',5'-monophosphate European Journal of Biochemistry. 121: 281-287. PMID 6277621 DOI: 10.1111/J.1432-1033.1982.Tb05783.X  0.302
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