Michael Paul Murphy - Publications

Affiliations: 
University of Kentucky University of Kentucky, Lexington, KY 
Area:
Alzheimer's disease

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ryan DG, Yang M, Prag HA, Blanco GR, Nikitopoulou E, Segarra-Mondejar M, Powell CA, Young T, Burger N, Miljkovic JL, Minczuk M, Murphy MP, von Kriegsheim A, Frezza C. Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism. Elife. 10. PMID 34939929 DOI: 10.7554/eLife.72593  1
2021 Mills EL, Harmon C, Jedrychowski MP, Xiao H, Gruszczyk AV, Bradshaw GA, Tran N, Garrity R, Laznik-Bogoslavski D, Szpyt J, Prendeville H, Lynch L, Murphy MP, Gygi SP, Spiegelman BM, et al. Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation. Cell Metabolism. PMID 34861155 DOI: 10.1016/j.cmet.2021.11.003  1
2021 Lakshman R, Spiroski AM, McIver LB, Murphy MP, Giussani DA. Noninvasive Biomarkers for Cardiovascular Dysfunction Programmed in Male Offspring of Adverse Pregnancy. Hypertension (Dallas, Tex. : 1979). 78: 1818-1828. PMID 34757774 DOI: 10.1161/HYPERTENSIONAHA.121.17926  1
2021 Burger N, James AM, Mulvey JF, Hoogewijs K, Ding S, Fearnley IM, Loureiro-López M, Norman AAI, Arndt S, Mottahedin A, Sauchanka O, Hartley RC, Krieg T, Murphy MP. ND3 Cys39 in complex I is exposed during mitochondrial respiration. Cell Chemical Biology. PMID 34739852 DOI: 10.1016/j.chembiol.2021.10.010  1
2021 Murphy MP, Schneider AM, LeDuc RC, Killen CJ, Adams WH, Brown NM. A Multivariate Analysis to Predict Total Hip Arthroplasty Dislocation With Preoperative Diagnosis, Surgical Approach, Spinal Pathology, Cup Orientation, and Head Size. The Journal of Arthroplasty. PMID 34548193 DOI: 10.1016/j.arth.2021.08.031  1
2021 Khellaf A, Garcia NM, Tajsic T, Alam A, Stovell MG, Killen MJ, Howe DJ, Guilfoyle MR, Jalloh I, Timofeev I, Murphy MP, Carpenter TA, Menon DK, Ercole A, Hutchinson PJ, et al. Focally administered succinate improves cerebral metabolism in traumatic brain injury patients with mitochondrial dysfunction. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211042112. PMID 34494481 DOI: 10.1177/0271678X211042112  1
2021 Taylor DA, Chacon-Alberty L, Sampaio LC, Del Hierro MG, Perin EC, Mesquita FCP, Henry TD, Traverse JH, Pepine CJ, Hare JM, Murphy MP, Yang PC, March KL, Vojvodic RW, Ebert RF, et al. Recommendations for Nomenclature and Definition Of Cell Products Intended for Human Cardiovascular Use. Cardiovascular Research. PMID 34387303 DOI: 10.1093/cvr/cvab270  1
2021 Nuevo-Tapioles C, Santacatterina F, Sánchez-Garrido B, Arenas CN, Robledo-Bérgamo A, Martínez-Valero P, Cantarero L, Pardo B, Hoenicka J, Murphy MP, Satrústegui J, Palau F, Cuezva JM. Effective therapeutic strategies in a pre-clinical mouse model of Charcot-Marie-tooth disease. Human Molecular Genetics. PMID 34274972 DOI: 10.1093/hmg/ddab207  1
2021 Mattox TA, Psaltis C, Weihbrecht K, Robidoux J, Kilburg-Basnyat B, Murphy MP, Gowdy KM, Anderson EJ. Prohibitin-1 Is a Dynamically Regulated Blood Protein With Cardioprotective Effects in Sepsis. Journal of the American Heart Association. e019877. PMID 34219469 DOI: 10.1161/JAHA.120.019877  1
2021 Cairns AG, McQuaker SJ, Murphy MP, Hartley RC. Insights on Targeting Small Molecules to the Mitochondrial Matrix and the Preparation of MitoB and MitoP as Exomarkers of Mitochondrial Hydrogen Peroxide. Methods in Molecular Biology (Clifton, N.J.). 2275: 87-117. PMID 34118033 DOI: 10.1007/978-1-0716-1262-0_6  1
2021 Dolezalova N, Gruszczyk A, Barkan K, Gamble JA, Galvin S, Moreth T, O'Holleran K, Mahbubani KT, Higgins JA, Gribble FM, Reimann F, Surmacki J, Andrews S, Casey JJ, Pampaloni F, ... Murphy MP, et al. Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets. Scientific Reports. 11: 10418. PMID 34001961 DOI: 10.1038/s41598-021-89853-6  1
2021 Murphy MP, Killen CJ, Ralles SJ, Brown NM, Song AJ, Wu K. The area method for measuring acetabular cup anteversion: An accurate and autonomous solution. Journal of Clinical Orthopaedics and Trauma. 18: 61-65. PMID 33996450 DOI: 10.1016/j.jcot.2021.04.002  1
2021 Esparza-Moltó PB, Romero-Carramiñana I, Núñez de Arenas C, Pereira MP, Blanco N, Pardo B, Bates GR, Sánchez-Castillo C, Artuch R, Murphy MP, Esteban JA, Cuezva JM. Generation of mitochondrial reactive oxygen species is controlled by ATPase inhibitory factor 1 and regulates cognition. Plos Biology. 19: e3001252. PMID 33983919 DOI: 10.1371/journal.pbio.3001252  1
2021 Tan SM, Lindblom RSJ, Ziemann M, Laskowski A, Granata C, Snelson M, Thallas-Bonke V, El-Osta A, Baeza-Garza CD, Caldwell ST, Hartley RC, Krieg T, Cooper ME, Murphy MP, Coughlan MT. Targeting Methylglyoxal in Diabetic Kidney Disease Using the Mitochondria-Targeted Compound MitoGamide. Nutrients. 13. PMID 33922959 DOI: 10.3390/nu13051457  1
2021 Caldwell ST, O'Byrne SN, Wilson C, Cvetko F, Murphy MP, McCarron JG, Hartley RC. Photoactivated release of membrane impermeant sulfonates inside cells. Chemical Communications (Cambridge, England). 57: 3917-3920. PMID 33871501 DOI: 10.1039/d0cc07713e  1
2021 Bolli R, Mitrani RD, Hare JM, Pepine CJ, Perin EC, Willerson JT, Traverse JH, Henry TD, Yang PC, Murphy MP, March KL, Schulman IH, Ikram S, Lee DP, O'Brien C, et al. A Phase II Study of Autologous Mesenchymal Stromal Cells and c-kit Positive Cardiac Cells, Alone or in Combination, in Patients with Ischemic Heart Failure: The CCTRN CONCERT-HF Trial. European Journal of Heart Failure. PMID 33811444 DOI: 10.1002/ejhf.2178  1
2021 Spiroski AM, Niu Y, Nicholas LM, Austin-Williams S, Camm EJ, Sutherland MR, Ashmore TJ, Skeffington KL, Logan A, Ozanne SE, Murphy MP, Giussani DA. Mitochondria antioxidant protection against cardiovascular dysfunction programmed by early-onset gestational hypoxia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21446. PMID 33788974 DOI: 10.1096/fj.202002705R  1
2021 Vicente-Gutierrez C, Bonora N, Jimenez-Blasco D, Lopez-Fabuel I, Bates G, Murphy MP, Almeida A, Bolaños JP. Abrogating mitochondrial ROS in neurons or astrocytes reveals cell-specific impact on mouse behaviour. Redox Biology. 41: 101917. PMID 33711713 DOI: 10.1016/j.redox.2021.101917  1
2021 Haas J, Frese KS, Sedaghat-Hamedani F, Kayvanpour E, Tappu R, Nietsch R, Tugrul OF, Wisdom M, Dietrich C, Amr A, Weis T, Niederdränk T, Murphy MP, Krieg T, Dörr M, et al. Energy Metabolites as Biomarkers in Ischemic and Dilated Cardiomyopathy. International Journal of Molecular Sciences. 22. PMID 33670449 DOI: 10.3390/ijms22041999  1
2021 Saeb-Parsy K, Martin JL, Summers DM, Watson CJE, Krieg T, Murphy MP. Correction to: Mitochondria as Therapeutic Targets in Transplantation: (Trends in Molecular Medicine 27:2 p:185-198, 2021). Trends in Molecular Medicine. PMID 33653669 DOI: 10.1016/j.molmed.2021.02.001  1
2021 Gaddale Devanna KK, Gawel JM, Prime TA, Cvetko F, Benincá C, Caldwell ST, Negoda A, Harrison A, James AM, Pavlov EV, Murphy MP, Hartley RC. Tetra-arylborate lipophilic anions as targeting groups. Chemical Communications (Cambridge, England). PMID 33634803 DOI: 10.1039/d0cc07924c  1
2021 Sampaziotis F, Muraro D, Tysoe OC, Sawiak S, Beach TE, Godfrey EM, Upponi SS, Brevini T, Wesley BT, Garcia-Bernardo J, Mahbubani K, Canu G, Gieseck R, Berntsen NL, Mulcahy VL, ... Murphy MP, et al. Cholangiocyte organoids can repair bile ducts after transplantation in the human liver. Science (New York, N.Y.). 371: 839-846. PMID 33602855 DOI: 10.1126/science.aaz6964  1
2021 Murphy MP, Brown NM. CORR Synthesis: When Should the Orthopaedic Surgeon Use Artificial Intelligence, Machine Learning, and Deep Learning? Clinical Orthopaedics and Related Research. PMID 33595930 DOI: 10.1097/CORR.0000000000001679  1
2021 Yin Z, Burger N, Kula-Alwar D, Aksentijević D, Bridges HR, Prag HA, Grba DN, Viscomi C, James AM, Mottahedin A, Krieg T, Murphy MP, Hirst J. Structural basis for a complex I mutation that blocks pathological ROS production. Nature Communications. 12: 707. PMID 33514727 DOI: 10.1038/s41467-021-20942-w  1
2021 Ganguly E, Kirschenman R, Spaans F, Holody CD, Phillips TEJ, Case CP, Cooke CM, Murphy MP, Lemieux H, Davidge ST. Nanoparticle-encapsulated antioxidant improves placental mitochondrial function in a sexually dimorphic manner in a rat model of prenatal hypoxia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. e21338. PMID 33428278 DOI: 10.1096/fj.202002193R  0.01
2020 Bundgaard A, James AM, Harbour ME, Murphy MP, Fago A. Stable mitochondrial CICIII2 supercomplex interactions in reptiles compared to homeothermic vertebrates. The Journal of Experimental Biology. PMID 34005504 DOI: 10.1242/jeb.223776  1
2020 Cvetko F, Caldwell ST, Higgins M, Suzuki T, Yamamoto M, Prag HA, Hartley RC, Dinkova-Kostova AT, Murphy MP. Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production. The Journal of Biological Chemistry. 296: 100169. PMID 33461950 DOI: 10.1074/jbc.RA120.016551  1
2020 Bolli R, Perin EC, Willerson JT, Yang PC, Traverse JH, Henry TD, Pepine CJ, Mitrani RD, Hare JM, Murphy MP, March KL, Ikram S, Lee DP, O'Brien C, Durand JB, et al. Allogeneic Mesenchymal Cell Therapy in Anthracycline-Induced Cardiomyopathy Heart Failure Patients: The CCTRN SENECA Trial. Jacc. Cardiooncology. 2: 581-595. PMID 33403362 DOI: 10.1016/j.jaccao.2020.09.001  1
2020 Al-Zubaidi U, Adhikari D, Cinar O, Zhang QH, Yuen WS, Murphy MP, Rombauts L, Robker RL, Carroll J. Mitochondria-targeted therapeutics, MitoQ and BGP-15, reverse aging-associated meiotic spindle defects in mouse and human oocytes. Human Reproduction (Oxford, England). PMID 33367783 DOI: 10.1093/humrep/deaa300  0.01
2020 Deragon MA, McCaig WD, Patel PS, Haluska RJ, Hodges AL, Sosunov SA, Murphy MP, Ten VS, LaRocca TJ. Mitochondrial ROS prime the hyperglycemic shift from apoptosis to necroptosis. Cell Death Discovery. 6: 132. PMID 33298902 DOI: 10.1038/s41420-020-00370-3  1
2020 Cvetko F, Caldwell ST, Higgins M, Suzuki T, Yamamoto M, Prag HA, Hartley RC, Dinkova-Kostova A, Murphy MP. Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production. The Journal of Biological Chemistry. PMID 33298526 DOI: 10.1074/jbc.RA120.016551  1
2020 Bjedov I, Cochemé HM, Foley A, Wieser D, Woodling NS, Castillo-Quan JI, Norvaisas P, Lujan C, Regan J, Toivonen JM, Murphy MP, Thornton J, Kinghorn KJ, Neufeld TP, Cabreiro F, et al. Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila. Plos Genetics. 16: e1009083. PMID 33253201 DOI: 10.1371/journal.pgen.1009083  1
2020 Wallace SJ, Murphy MP, Schiffman CJ, Hopkinson WJ, Brown NM. Demographic data is more predictive of component size than digital radiographic templating in total knee arthroplasty. Knee Surgery & Related Research. 32: 63. PMID 33225974 DOI: 10.1186/s43019-020-00075-y  1
2020 James AM, Smith AC, Ding S, Houghton JW, Robinson AJ, Antrobus R, Fearnley IM, Murphy MP. Nucleotide-binding sites can enhance N-acylation of nearby protein lysine residues. Scientific Reports. 10: 20254. PMID 33219268 DOI: 10.1038/s41598-020-77261-1  1
2020 Timm KN, Perera C, Ball V, Henry JA, Miller JJ, Kerr M, West JA, Sharma E, Broxholme J, Logan A, Savic D, Dodd MS, Griffin JL, Murphy MP, Heather LC, et al. Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI. Communications Biology. 3: 692. PMID 33214680 DOI: 10.1038/s42003-020-01440-z  1
2020 Strong R, Miller RA, Bogue M, Fernandez E, Javors MA, Libert S, Marinez PA, Murphy MP, Musi N, Nelson JF, Petrascheck M, Reifsnyder P, Richardson A, Salmon AB, Macchiarini F, et al. Rapamycin-mediated mouse lifespan extension: Late-life dosage regimes with sex-specific effects. Aging Cell. e13269. PMID 33145977 DOI: 10.1111/acel.13269  0.01
2020 Dungan CM, Valentino TR, Vechetti Jr IJ, Zdunek CJ, Murphy MP, Lin AL, McCarthy J, Peterson CA. Exercise-mediated alteration of hippocampal Dicer mRNA and miRNAs is associated with lower BACE1 gene expression and Aβ in female 3xTg-AD mice. Journal of Neurophysiology. PMID 33052800 DOI: 10.1152/jn.00503.2020  0.01
2020 Pala L, Senn HM, Caldwell ST, Prime TA, Warrington S, Bright TP, Prag HA, Wilson C, Murphy MP, Hartley RC. Enhancing the Mitochondrial Uptake of Phosphonium Cations by Carboxylic Acid Incorporation. Frontiers in Chemistry. 8: 783. PMID 33033715 DOI: 10.3389/fchem.2020.00783  1
2020 Park M, Nishimura T, Baeza-Garza CD, Caldwell ST, Pun PBL, Prag HA, Young T, Sauchanka O, Logan A, Forkink M, Gruszczyk AV, Prime TA, Arndt S, Naudi A, Pamplona R, ... Murphy MP, et al. Confirmation of the Cardioprotective Effect of MitoGamide in the Diabetic Heart. Cardiovascular Drugs and Therapy. PMID 32979176 DOI: 10.1007/s10557-020-07086-7  1
2020 Saeb-Parsy K, Martin JL, Summers DM, Watson CJE, Krieg T, Murphy MP. Mitochondria as Therapeutic Targets in Transplantation. Trends in Molecular Medicine. PMID 32952044 DOI: 10.1016/j.molmed.2020.08.001  1
2020 Beach TE, Prag HA, Pala L, Logan A, Huang MM, Gruszczyk AV, Martin JL, Mahbubani K, Hamed MO, Hosgood SA, Nicholson ML, James AM, Hartley RC, Murphy MP, Saeb-Parsy K. Targeting succinate dehydrogenase with malonate ester prodrugs decreases renal ischemia reperfusion injury. Redox Biology. 36: 101640. PMID 32863205 DOI: 10.1016/j.redox.2020.101640  1
2020 Gao K, Cheng M, Zuo X, Lin J, Hoogewijs K, Murphy MP, Fu XD, Zhang X. Active RNA interference in mitochondria. Cell Research. PMID 32807841 DOI: 10.1038/S41422-020-00394-5  1
2020 Prag HA, Gruszczyk AV, Huang MM, Beach TE, Young T, Tronci L, Nikitopoulou E, Mulvey JF, Ascione R, Hadjihambi A, Shattock MJ, Pellerin L, Saeb-Parsy K, Frezza C, James AM, ... Murphy MP, et al. Mechanism of succinate efflux upon reperfusion of the ischemic heart. Cardiovascular Research. PMID 32766828 DOI: 10.1093/Cvr/Cvaa148  1
2020 Cunnane SC, Trushina E, Morland C, Prigione A, Casadesus G, Andrews ZB, Beal MF, Bergersen LH, Brinton RD, de la Monte S, Eckert A, Harvey J, Jeggo R, Jhamandas JH, Kann O, ... Murphy MP, et al. Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing. Nature Reviews. Drug Discovery. PMID 32709961 DOI: 10.1038/S41573-020-0072-X  1
2020 Prag HA, Kula-Alwar D, Pala L, Caldwell ST, Beach TE, James AM, Saeb-Parsy K, Krieg T, Hartley RC, Murphy MP. Selective Delivery of Dicarboxylates to Mitochondria by Conjugation to a Lipophilic Cation via a Cleavable Linker. Molecular Pharmaceutics. PMID 32692564 DOI: 10.1021/acs.molpharmaceut.0c00533  1
2020 Prag HA, Pala L, Kula-Alwar D, Mulvey JF, Luping D, Beach TE, Booty LM, Hall AR, Logan A, Sauchanka V, Caldwell ST, Robb EL, James AM, Xu Z, Saeb-Parsy K, ... Murphy MP, et al. Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo. Cardiovascular Drugs and Therapy. PMID 32648168 DOI: 10.1007/s10557-020-07033-6  1
2020 Momcilovic M, Shirihai O, Murphy MP, Koehler CM, Sadeghi S, Shackelford DB. Reply to: In vivo quantification of mitochondrial membrane potential. Nature. 583: E19-E20. PMID 32641810 DOI: 10.1038/S41586-020-2367-9  1
2020 Chowdhury AR, Zielonka J, Kalyanaraman B, Hartley RC, Murphy MP, Avadhani NG. Mitochondria-targeted paraquat and metformin mediate ROS production to induce multiple pathways of retrograde signaling: A dose-dependent phenomenon. Redox Biology. 36: 101606. PMID 32604037 DOI: 10.1016/J.Redox.2020.101606  1
2020 Greenway R, Barts N, Henpita C, Brown AP, Arias Rodriguez L, Rodríguez Peña CM, Arndt S, Lau GY, Murphy MP, Wu L, Lin D, Tobler M, Kelley JL, Shaw JH. Convergent evolution of conserved mitochondrial pathways underlies repeated adaptation to extreme environments. Proceedings of the National Academy of Sciences of the United States of America. PMID 32586956 DOI: 10.1073/Pnas.2004223117  1
2020 Rossman MJ, Gioscia-Ryan RA, Clayton ZS, Murphy MP, Seals DR. Targeting mitochondrial fitness as a strategy for healthy vascular aging. Clinical Science (London, England : 1979). 134: 1491-1519. PMID 32584404 DOI: 10.1042/Cs20190559  1
2020 Jing C, Castro-Dopico T, Richoz N, Tuong ZK, Ferdinand JR, Lok LSC, Loudon KW, Banham GD, Mathews RJ, Cader Z, Fitzpatrick S, Bashant KR, Kaplan MJ, Kaser A, Johnson RS, Murphy MP, et al. Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis. Proceedings of the National Academy of Sciences of the United States of America. PMID 32541026 DOI: 10.1073/Pnas.2000943117  1
2020 Teulings NEWD, Garrud TAC, Niu Y, Skeffington KL, Beck C, Itani N, Conlon FG, Botting KJ, Nicholas LM, Ashmore TJ, Blackmore HL, Tong W, Camm EJ, Derks JB, Logan A, Murphy MP, et al. Isolating adverse effects of glucocorticoids on the embryonic cardiovascular system. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32502311 DOI: 10.1096/Fj.202000697R  1
2020 Liao JL, Wang SK, Maijub JG, Gupta AK, Sawchuk AP, Motaganahalli RL, Murphy MP, Fajardo AC. Perioperative and Long-Term Results of Female Zenith Fenestrated Aortic Repair. Annals of Vascular Surgery. PMID 32479879 DOI: 10.1016/j.avsg.2020.05.036  1
2020 Olesen MA, Torres AK, Jara C, Murphy MP, Tapia-Rojas C. Premature synaptic mitochondrial dysfunction in the hippocampus during aging contributes to memory loss. Redox Biology. 34: 101558. PMID 32447261 DOI: 10.1016/j.redox.2020.101558  0.01
2020 Riordan F, Racine E, Phillip ET, Bradley C, Lorencatto F, Murphy M, Murphy A, Browne J, Smith SM, Kearney PM, McHugh SM. Development of an intervention to facilitate implementation and uptake of diabetic retinopathy screening. Implementation Science : Is. 15: 34. PMID 32429983 DOI: 10.1186/s13012-020-00982-4  1
2020 Riordan F, Racine E, Smith SM, Murphy A, Browne J, Kearney PM, Bradley C, James M, Murphy M, McHugh SM. Feasibility of an implementation intervention to increase attendance at diabetic retinopathy screening: protocol for a cluster randomised pilot trial. Pilot and Feasibility Studies. 6: 64. PMID 32426158 DOI: 10.1186/s40814-020-00608-y  1
2020 Murphy MP, O'Neill LAJ. How should we talk about metabolism? Nature Immunology. PMID 32409776 DOI: 10.1038/s41590-020-0691-8  1
2020 Cook M, Murphy M, Bulluss K, D'Souza W, Plummer C, Priest E, Williams C, Sharan A, Fisher R, Pincus S, Distad E, Anchordoquy T, Abrams D. Anti-seizure therapy with a long-term, implanted intra-cerebroventricular delivery system for drug-resistant epilepsy: A first-in-man study. Eclinicalmedicine. 22: 100326. PMID 32395709 DOI: 10.1016/J.Eclinm.2020.100326  0.01
2020 Bundgaard A, James AM, Harbour ME, Murphy MP, Fago A. Stable mitochondrial CICIII supercomplex interactions in reptiles compared to homeothermic vertebrates. The Journal of Experimental Biology. PMID 32393546 DOI: 10.1242/jeb.223776  1
2020 Fernández-Del-Río L, Kelly M, Contreras J, Bradley MC, James AM, Murphy MP, Payne GS, Clarke CF. Genes and lipids that impact uptake and assimilation of exogenous coenzyme Q in Saccharomyces cerevisiae. Free Radical Biology & Medicine. PMID 32387128 DOI: 10.1016/J.Freeradbiomed.2020.04.029  1
2020 Killen CJ, Murphy MP, Ralles SJ, Khayatzadeh S, Brown NM, Patwardhan AG, Havey RM, Wu K. Characterising acetabular component orientation with pelvic motion during total hip arthroplasty. Hip International : the Journal of Clinical and Experimental Research On Hip Pathology and Therapy. 1120700020925013. PMID 32375525 DOI: 10.1177/1120700020925013  1
2020 Jedrychowski MP, Lu GZ, Szpyt J, Mariotti M, Garrity R, Paulo JA, Schweppe DK, Laznik-Bogoslavski D, Kazak L, Murphy MP, Gladyshev VN, Gygi SP, Chouchani ET, Spiegelman BM. Facultative protein selenation regulates redox sensitivity, adipose tissue thermogenesis, and obesity. Proceedings of the National Academy of Sciences of the United States of America. PMID 32358195 DOI: 10.1073/Pnas.2001387117  1
2020 Fortner KA, Blanco LP, Buskiewicz I, Huang N, Gibson PC, Cook DL, Pedersen HL, Yuen PST, Murphy MP, Perl A, Kaplan MJ, Budd RC. Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL- mice. Lupus Science & Medicine. 7. PMID 32343673 DOI: 10.1136/lupus-2020-000387  1
2020 Philip J, Collins A, Panozzo S, Staker J, Murphy M. Mapping the nature of distress raised by patients with high-grade glioma and their family caregivers: a descriptive longitudinal study. Neuro-Oncology Practice. 7: 103-110. PMID 32257289 DOI: 10.1093/nop/npz032  0.01
2020 Murphy MP, King JR, Leckie KE. Deletion of Expression in Aortic Smooth Muscle Cells Ameliorates Aortic Dissection. Jacc. Basic to Translational Science. 5: 145-147. PMID 32142064 DOI: 10.1016/j.jacbts.2020.01.006  0.01
2020 Murphy M, Killen C, Lynch K, Cohen J, Summers H, Stover M, Lack W. Minimally Invasive Medial Plate Osteosynthesis of High Energy Pediatric Tibia Fractures. Journal of Orthopaedic Trauma. PMID 32097234 DOI: 10.1097/BOT.0000000000001751  0.01
2020 Tate M, Higgins GC, De Blasio MJ, Lindblom R, Prakoso D, Deo M, Kiriazis H, Park M, Baeza-Garza CD, Caldwell ST, Hartley RC, Krieg T, Murphy MP, Coughlan MT, Ritchie RH. Correction to: The Mitochondria-Targeted Methylglyoxal Sequestering Compound, MitoGamide, Is Cardioprotective in the Diabetic Heart. Cardiovascular Drugs and Therapy. PMID 32062792 DOI: 10.1007/s10557-019-06929-2  1
2020 Murphy MP, McEnery T, McQuillan K, McElvaney OF, McElvaney OJ, Landers S, Coleman O, Bussayajirapong A, Hawkins P, Henry M, Meleady P, Reeves EP, McElvaney NG. Alpha-1 antitrypsin therapy modulates the neutrophil membrane proteome and secretome. The European Respiratory Journal. PMID 32060059 DOI: 10.1183/13993003.01678-2019  0.01
2020 Szibor M, Schreckenberg R, Gizatullina Z, Dufour E, Wiesnet M, Dhandapani PK, Debska-Vielhaber G, Heidler J, Wittig I, Nyman TA, Gärtner U, Hall AR, Pell V, Viscomi C, Krieg T, Murphy MP, et al. Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia. Journal of Cellular and Molecular Medicine. PMID 32040259 DOI: 10.1111/jcmm.15043  1
2020 Coppa A, Guha S, Fourcade S, Janani Parameswaran, Ruiz M, Moser AB, Schlüter A, Murphy MP, Lizcano JM, Miranda-Vizuete A, Dalfó E, Pujol A. The peroxisomal fatty acid transporter ABCD1/PMP-4 is required in the C. elegans hypodermis for axonal maintenance: A worm model for adrenoleukodystrophy. Free Radical Biology & Medicine. PMID 32017990 DOI: 10.1016/j.freeradbiomed.2020.01.177  0.01
2020 Killen CJ, Murphy MP, Hopkinson WJ, Harrington MA, Adams WH, Rees HW. Minimum twelve-year follow-up of fixed- vs mobile-bearing total knee arthroplasty: Double blinded randomized trial. Journal of Clinical Orthopaedics and Trauma. 11: 154-159. PMID 32002005 DOI: 10.1016/j.jcot.2019.03.019  1
2019 Martin JL, Costa ASH, Gruszczyk AV, Beach TE, Allen FM, Prag HA, Hinchy EC, Mahbubani K, Hamed M, Tronci L, Nikitopoulou E, James AM, Krieg T, Robinson AJ, Huang MH, ... Murphy MP, et al. Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation. Nature Metabolism. 1: 966-974. PMID 32395697 DOI: 10.1038/s42255-019-0115-y  1
2019 Murphy MP, Wallace SJ, Brown NM. Prospective Comparison of Available Primary Total Knee Arthroplasty Sizing Equations. The Journal of Arthroplasty. PMID 31882347 DOI: 10.1016/j.arth.2019.11.041  1
2019 Burger N, Logan A, Prime TA, Mottahedin A, Caldwell ST, Krieg T, Hartley RC, James AM, Murphy MP. A sensitive mass spectrometric assay for mitochondrial CoQ pool redox state in vivo. Free Radical Biology & Medicine. PMID 31811922 DOI: 10.1016/j.freeradbiomed.2019.11.028  1
2019 Pinho BR, Duarte AI, Canas PM, Moreira PI, Murphy MP, Oliveira JA. The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice. Free Radical Biology & Medicine. PMID 31751762 DOI: 10.1016/j.freeradbiomed.2019.11.021  1
2019 Tate M, Higgins GC, De Blasio MJ, Lindblom R, Prakoso D, Deo M, Kiriazis H, Park M, Baeza-Garza CD, Caldwell ST, Hartley RC, Krieg T, Murphy MP, Coughlan MT, Ritchie RH. The Mitochondria-Targeted Methylglyoxal Sequestering Compound, MitoGamide, Is Cardioprotective in the Diabetic Heart. Cardiovascular Drugs and Therapy. PMID 31654171 DOI: 10.1007/s10557-019-06914-9  1
2019 Lau GY, Arndt S, Murphy MP, Richards JG. Species and tissue specific differences in ROS metabolism to hypoxia- and hyperoxia-recovery exposure in marine sculpins. The Journal of Experimental Biology. PMID 31628206 DOI: 10.1242/jeb.206896  1
2019 Murphy MP, Killen CJ, Ralles SJ, Brown NM, Hopkinson WJ, Wu K. A precise method for determining acetabular component anteversion after total hip arthroplasty. The Bone & Joint Journal. 101: 1042-1049. PMID 31474147 DOI: 10.1302/0301-620X.101B9.BJJ-2019-0085.R1  1
2019 Wang SK, Miladore JN, Drucker NA, Fajardo A, Lemmon GW, Dalsing MC, Murphy MP, Motaganahalli RL. Procedural Complexity of TransCarotid Artery Revascularization (TCAR) is not Increased in Irradiated and Reoperative Necks. Annals of Vascular Surgery. PMID 31394232 DOI: 10.1016/j.avsg.2019.05.063  1
2019 Murphy MP. Rerouting metabolism to activate macrophages. Nature Immunology. PMID 31384059 DOI: 10.1038/s41590-019-0455-5  0.01
2019 Lim PJ, Duarte TL, Arezes J, Garcia-Santos D, Hamdi A, Pasricha SR, Armitage AE, Mehta H, Wideman S, Santos AG, Santos-Gonçalves A, Morovat A, Hughes JR, Soilleux E, Wang CY, ... Murphy MP, et al. Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin. Nature Metabolism. 1: 519-531. PMID 31276102 DOI: 10.1038/s42255-019-0063-6  1
2019 Humpton TJ, Alagesan B, DeNicola GM, Lu D, Yordanov GN, Leonhardt CS, Yao MA, Alagesan P, Zaatari MN, Park Y, Skepper JN, Macleod KF, Perez-Mancera PA, Murphy MP, Evan GI, et al. Oncogenic Kras induces Nix-mediated mitophagy to promote pancreatic cancer. Cancer Discovery. PMID 31263025 DOI: 10.1158/2159-8290.Cd-18-1409  0.01
2019 Robb EL, Hall AR, Prime TA, Eaton S, Szibor M, Viscomi C, James AM, Murphy MP. Correction: Control of mitochondrial superoxide production by reverse electron transport at complex I. The Journal of Biological Chemistry. 294: 7966. PMID 31076523 DOI: 10.1074/jbc.AAC119.008929  1
2019 Lau GY, Barts N, Hartley RC, Tobler M, Richards JG, Murphy MP, Arndt S. Detection of changes in mitochondrial hydrogen sulfide in the fish model (Poeciliidae). Biology Open. 8. PMID 31072908 DOI: 10.1242/Bio.041467  1
2019 Zhang L, Fernandez-Kim SO, Beckett TL, Niedowicz DM, Kohler K, Dasuri K, Bruce-Keller AJ, Murphy MP, Keller JN. The db mutation improves memory in younger mice in a model of Alzheimer's disease. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 31034991 DOI: 10.1016/J.Bbadis.2019.04.013  1
2019 Ryan DG, Murphy MP, Frezza C, Prag HA, Chouchani ET, O'Neill LA, Mills EL. Coupling Krebs cycle metabolites to signalling in immunity and cancer. Nature Metabolism. 1: 16-33. PMID 31032474 DOI: 10.1038/s42255-018-0014-7  1
2019 Kohlhauer M, Pell VR, Burger N, Spiroski AM, Gruszczyk A, Mulvey JF, Mottahedin A, Costa ASH, Frezza C, Ghaleh B, Murphy MP, Tissier R, Krieg T. Correction to: Protection against cardiac ischemia-reperfusion injury by hypothermia and by inhibition of succinate accumulation and oxidation is additive. Basic Research in Cardiology. 114: 24. PMID 30968226 DOI: 10.1007/s00395-019-0731-4  1
2019 Kohlhauer M, Pell VR, Burger N, Spiroski AM, Gruszczyk A, Mulvey JF, Mottahedin A, Costa ASH, Frezza C, Ghaleh B, Murphy MP, Tissier R, Krieg T. Protection against cardiac ischemia-reperfusion injury by hypothermia and by inhibition of succinate accumulation and oxidation is additive. Basic Research in Cardiology. 114: 18. PMID 30877396 DOI: 10.1007/s00395-019-0727-0  1
2019 Murphy M, Öngür D. Decreased peak alpha frequency and impaired visual evoked potentials in first episode psychosis. Neuroimage. Clinical. 22: 101693. PMID 30825710 DOI: 10.1016/j.nicl.2019.101693  0.01
2019 Escribano-Lopez I, Bañuls C, Diaz-Morales N, Iannantuoni F, Rovira-Llopis S, Gomis R, Rocha M, Hernandez-Mijares A, Murphy MP, Victor VM. The Mitochondria-Targeted Antioxidant MitoQ Modulates Mitochondrial Function and Endoplasmic Reticulum Stress in Pancreatic β Cells Exposed to Hyperglycaemia. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 52: 186-197. PMID 30816667 DOI: 10.33594/000000013  1
2019 Bundgaard A, James AM, Gruszczyk AV, Martin J, Murphy MP, Fago A. Metabolic adaptations during extreme anoxia in the turtle heart and their implications for ischemia-reperfusion injury. Scientific Reports. 9: 2850. PMID 30808950 DOI: 10.1038/s41598-019-39836-5  1
2019 Antonucci S, Mulvey JF, Burger N, Di Sante M, Hall AR, Hinchy EC, Caldwell ST, Gruszczyk AV, Deshwal S, Hartley RC, Kaludercic N, Murphy MP, Di Lisa F, Krieg T. Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis. Free Radical Biology & Medicine. PMID 30731114 DOI: 10.1016/j.freeradbiomed.2019.01.034  1
2019 Gómez-Cabañas L, López-Cotarelo P, Criado-García O, Murphy MP, Boya P, Rodríguez-Fernández JL. Immunological Synapse Formation Induces Mitochondrial Clustering and Mitophagy in Dendritic Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 30718295 DOI: 10.4049/jimmunol.1800575  0.01
2019 Wang SK, Lemmon GW, Gupta AK, Dalsing MC, Sawchuk AP, Motaganahalli RL, Murphy MP, Fajardo A. Aggressive Surveillance is Needed to Detect Endoleaks and Junctional Separation Between Device Components after Zenith Fenestrated Aortic Reconstruction. Annals of Vascular Surgery. PMID 30684629 DOI: 10.1016/j.avsg.2018.09.038  1
2019 Galván-Peña S, Carroll RG, Newman C, Hinchy EC, Palsson-McDermott E, Robinson EK, Covarrubias S, Nadin A, James AM, Haneklaus M, Carpenter S, Kelly VP, Murphy MP, Modis LK, O'Neill LA. Malonylation of GAPDH is an inflammatory signal in macrophages. Nature Communications. 10: 338. PMID 30659183 DOI: 10.1038/S41467-018-08187-6  1
2019 van Golen RF, Reiniers MJ, Marsman G, Alles LK, van Rooyen DM, Petri B, Van der Mark VA, van Beek AA, Meijer B, Maas MA, Zeerleder S, Verheij J, Farrell GC, Luken BM, Teoh NC, ... Murphy MP, et al. The damage-associated molecular pattern HMGB1 is released early after clinical hepatic ischemia/reperfusion. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30658161 DOI: 10.1016/j.bbadis.2019.01.014  0.01
2018 Kays JK, Liang TW, Zimmers TA, Milgrom DP, Abduljabar H, Young A, Kim BJ, Bell TM, Fajardo A, Murphy MP, Koniaris LG. Sarcopenia is a Significant Predictor of Mortality After Abdominal Aortic Aneurysm Repair. Jcsm Clinical Reports. 3. PMID 30984911  1
2018 Booty LM, Gawel JM, Cvetko F, Caldwell ST, Hall AR, Mulvey JF, James AM, Hinchy EC, Prime TA, Arndt S, Beninca C, Bright TP, Clatworthy MR, Ferdinand JR, Prag HA, ... Murphy MP, et al. Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo. Cell Chemical Biology. PMID 30713096 DOI: 10.1016/j.chembiol.2018.12.002  1
2018 Wang SK, Lemmon GW, Gupta AK, Dalsing MC, Sawchuk AP, Motaganahalli RL, Murphy MP, Fajardo A. Fenestrated endovascular aneurysm repair-induced acute kidney injury does not result in chronic renal dysfunction. Journal of Vascular Surgery. PMID 30591295 DOI: 10.1016/j.jvs.2018.09.044  1
2018 Hancock M, Hafstad AD, Nabeebaccus AA, Catibog N, Logan A, Smyrnias I, Hansen SS, Lanner J, Schröder K, Murphy MP, Shah AM, Zhang M. Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. Elife. 7. PMID 30589411 DOI: 10.7554/eLife.41044  1
2018 Signes A, Cerutti R, Dickson AS, Benincá C, Hinchy EC, Ghezzi D, Carrozzo R, Bertini E, Murphy MP, Nathan JA, Viscomi C, Fernandez-Vizarra E, Zeviani M. APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS. Embo Molecular Medicine. PMID 30552096 DOI: 10.15252/emmm.201809582  1
2018 Kim YR, Baek JI, Kim SH, Kim MA, Lee B, Ryu N, Kim KH, Choi DG, Kim HM, Murphy MP, Macpherson G, Choo YS, Bok J, Lee KY, Park JW, et al. Therapeutic potential of the mitochondria-targeted antioxidant MitoQ in mitochondrial-ROS induced sensorineural hearing loss caused by Idh2 deficiency. Redox Biology. 20: 544-555. PMID 30508699 DOI: 10.1016/J.Redox.2018.11.013  1
2018 Murphy MP, Rammer JR, Vinehout KL, Caballero MR, Cornwell CM, Fritz JM, Harris GF. Inverse Kinematic Assessment of Rehabilitative Therapy in Children Using Orthotics. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2018: 2813-2816. PMID 30440986 DOI: 10.1109/EMBC.2018.8512863  0.01
2018 Murphy MP, Hartley RC. Mitochondria as a therapeutic target for common pathologies. Nature Reviews. Drug Discovery. PMID 30393373 DOI: 10.1038/nrd.2018.174  1
2018 Pinho BR, Reis SD, Hartley RC, Murphy MP, Oliveira JMA. Mitochondrial superoxide generation induces a parkinsonian phenotype in zebrafish and huntingtin aggregation in human cells. Free Radical Biology & Medicine. PMID 30389496 DOI: 10.1016/j.freeradbiomed.2018.10.446  1
2018 Wang SK, Fajardo A, Sawchuk AP, Lemmon GW, Dalsing MC, Gupta AK, Murphy MP, Motaganahalli RL. Outcomes associated with a transcarotid artery revascularization-centered protocol in high-risk carotid revascularizations using the ENROUTE neuroprotection system. Journal of Vascular Surgery. PMID 30301690 DOI: 10.1016/j.jvs.2018.06.222  1
2018 Nuzzo AM, Camm EJ, Sferruzzi-Perri AN, Ashmore TJ, Yung HW, Cindrova-Davies T, Spiroski AM, Sutherland MR, Logan A, Austin-Williams S, Burton GJ, Rolfo A, Todros T, Murphy MP, Giussani DA. Placental adaptation to early-onset hypoxic pregnancy and mitochondria-targeted antioxidant therapy in rat. The American Journal of Pathology. PMID 30248337 DOI: 10.1016/j.ajpath.2018.07.027  1
2018 Hinchy EC, Gruszczyk AV, Willows R, Navaratnam N, Hall AR, Bates G, Bright TP, Krieg T, Carling D, Murphy MP. Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly. The Journal of Biological Chemistry. PMID 30232152 DOI: 10.1074/Jbc.Ra118.002579  1
2018 Stovell MG, Mada MO, Carpenter TA, Yan JL, Guilfoyle MR, Jalloh I, Welsh KE, Helmy A, Howe DJ, Grice P, Mason A, Giorgi-Coll S, Gallagher CN, Murphy MP, Menon DK, et al. Phosphorus spectroscopy in acute TBI demonstrates metabolic changes that relate to outcome in the presence of normal structural MRI. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18799176. PMID 30226401 DOI: 10.1177/0271678X18799176  1
2018 Murphy MP. Metabolic control of ferroptosis in cancer. Nature Cell Biology. PMID 30224762 DOI: 10.1038/s41556-018-0209-x  0.01
2018 Ferguson DCJ, Smerdon GR, Harries LW, Dodd NJF, Murphy MP, Curnow A, Winyard PG. Altered cellular redox homeostasis and redox responses under standard oxygen cell culture conditions versus physioxia. Free Radical Biology & Medicine. PMID 30142453 DOI: 10.1016/j.freeradbiomed.2018.08.025  0.01
2018 James AM, Smith CL, Smith AC, Robinson AJ, Hoogewijs K, Murphy MP. The Causes and Consequences of Nonenzymatic Protein Acylation. Trends in Biochemical Sciences. PMID 30131192 DOI: 10.1016/j.tibs.2018.07.002  1
2018 Pell VR, Spiroski AM, Mulvey J, Burger N, Costa ASH, Logan A, Gruszczyk AV, Rosa T, James AM, Frezza C, Murphy MP, Krieg T. Ischemic preconditioning protects against cardiac ischemia reperfusion injury without affecting succinate accumulation or oxidation. Journal of Molecular and Cellular Cardiology. PMID 30118790 DOI: 10.1016/j.yjmcc.2018.08.010  1
2018 Murphy MP, O'Neill LAJ. Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers. Cell. 174: 780-784. PMID 30096309 DOI: 10.1016/j.cell.2018.07.030  1
2018 James AM, Smith AC, Smith CL, Robinson AJ, Murphy MP. Proximal Cysteines that Enhance Lysine N-Acetylation of Cytosolic Proteins in Mice Are Less Conserved in Longer-Living Species. Cell Reports. 24: 1445-1455. PMID 30089256 DOI: 10.1016/j.celrep.2018.07.007  1
2018 Murphy MP. Newly made mitochondrial DNA drives inflammation. Nature. 560: 176-177. PMID 30076376 DOI: 10.1038/d41586-018-05764-z  0.01
2018 Kim JH, Choi TG, Park S, Yun HR, Nguyen NNY, Jo YH, Jang M, Kim J, Kim J, Kang I, Ha J, Murphy MP, Tang DG, Kim SS. Mitochondrial ROS-derived PTEN oxidation activates PI3K pathway for mTOR-induced myogenic autophagy. Cell Death and Differentiation. PMID 30042494 DOI: 10.1038/S41418-018-0165-9  1
2018 Stovell MG, Mada MO, Helmy A, Carpenter TA, Thelin EP, Yan JL, Guilfoyle MR, Jalloh I, Howe DJ, Grice P, Mason A, Giorgi-Coll S, Gallagher CN, Murphy MP, Menon DK, et al. The effect of succinate on brain NADH/NAD redox state and high energy phosphate metabolism in acute traumatic brain injury. Scientific Reports. 8: 11140. PMID 30042490 DOI: 10.1038/S41598-018-29255-3  1
2018 Kim M, Stepanova A, Niatsetskaya Z, Sosunov S, Arndt S, Murphy MP, Galkin A, Ten VS. Attenuation of oxidative damage by targeting mitochondrial complex I in neonatal hypoxic-ischemic brain injury. Free Radical Biology & Medicine. 124: 517-524. PMID 30037775 DOI: 10.1016/J.Freeradbiomed.2018.06.040  1
2018 Mills EL, Pierce KA, Jedrychowski MP, Garrity R, Winther S, Vidoni S, Yoneshiro T, Spinelli JB, Lu GZ, Kazak L, Banks AS, Haigis MC, Kajimura S, Murphy MP, Gygi SP, et al. Accumulation of succinate controls activation of adipose tissue thermogenesis. Nature. PMID 30022159 DOI: 10.1038/S41586-018-0353-2  1
2018 Wiseman FK, Pulford LJ, Barkus C, Liao F, Portelius E, Webb R, Chávez-Gutiérrez L, Cleverley K, Noy S, Sheppard O, Collins T, Powell C, Sarell CJ, Rickman M, Choong X, ... Murphy MP, et al. Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP. Brain : a Journal of Neurology. PMID 29945247 DOI: 10.1093/Brain/Awy159  0.01
2018 Wang SK, Drucker NA, Dalsing MC, Sawchuk AP, Gupta AK, Motaganahalli RL, Murphy MP, Fajardo A. Adjunctive visceral artery chimney in patients undergoing Zenith Fenestrated aortic repair. Journal of Vascular Surgery. PMID 29929822 DOI: 10.1016/j.jvs.2018.03.421  1
2018 Wang SK, Green LA, Gutwein AR, Kenyon B, Motaganahalli RL, Fajardo A, Gupta AK, Murphy MP. Metformin does not reduce inflammation in diabetics with abdominal aortic aneurysm or at high risk of abdominal aortic aneurysm formation. Vascular. 1708538118777657. PMID 29871586 DOI: 10.1177/1708538118777657  1
2018 Martin JL, Gruszczyk AV, Beach TE, Murphy MP, Saeb-Parsy K. Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury. Pediatric Nephrology (Berlin, Germany). PMID 29860579 DOI: 10.1007/s00467-018-3984-5  1
2018 Xi Y, Feng D, Tao K, Wang R, Shi Y, Qin H, Murphy MP, Yang Q, Zhao G. MitoQ protects dopaminergic neurons in a 6-OHDA induced PD model by enhancing Mfn2-dependent mitochondrial fusion via activation of PGC-1α. Biochimica Et Biophysica Acta. PMID 29842922 DOI: 10.1016/j.bbadis.2018.05.018  1
2018 Wang SK, Drucker NA, Sawchuk AP, Lemmon GW, Dalsing MC, Motaganahalli RL, Murphy MP, Fajardo A. Use of the Zenith Fenestrated platform to rescue failing endovascular and open aortic reconstructions is safe and technically feasible. Journal of Vascular Surgery. PMID 29784569 DOI: 10.1016/j.jvs.2018.01.038  1
2018 Foote K, Reinhold J, Yu EPK, Figg NL, Finigan A, Murphy MP, Bennett MR. Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice. Aging Cell. e12773. PMID 29745022 DOI: 10.1111/acel.12773  1
2018 Robb EL, Hall AR, Prime TA, Eaton S, Szibor M, Viscomi C, James AM, Murphy MP. Control of mitochondrial superoxide production by reverse electron transport at complex I. The Journal of Biological Chemistry. PMID 29743240 DOI: 10.1074/jbc.RA118.003647  1
2018 Wang SK, Green LA, Gutwein AR, Drucker NA, Motaganahalli RL, Gupta AK, Fajardo A, Murphy MP. Description of human AAA by cytokine and immune cell aberrations compared to risk-factor matched controls. Surgery. PMID 29716755 DOI: 10.1016/j.surg.2018.03.002  1
2018 Ma D, Wang AC, Parikh I, Green SJ, Hoffman JD, Chlipala G, Murphy MP, Sokola BS, Bauer B, Hartz AMS, Lin AL. Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice. Scientific Reports. 8: 6670. PMID 29703936 DOI: 10.1038/S41598-018-25190-5  1
2018 Adelsperger AR, Phillips EH, Ibriga HS, Craig BA, Green LA, Murphy MP, Goergen CJ. Development and growth trends in angiotensin II-induced murine dissecting abdominal aortic aneurysms. Physiological Reports. 6: e13668. PMID 29696811 DOI: 10.14814/Phy2.13668  1
2018 Jalloh I, Helmy A, Howe D, Shannon RJ, Grice P, Mason A, Gallagher CN, Murphy M, Pickard J, Menon D, Carpenter TA, Hutchinson PJ, Carpenter K. A comparison of oxidative lactate metabolism in traumatically injured brain and control brain. Journal of Neurotrauma. PMID 29690859 DOI: 10.1089/Neu.2017.5459  1
2018 Rossman MJ, Santos-Parker JR, Steward CAC, Bispham NZ, Cuevas LM, Rosenberg HL, Woodward KA, Chonchol M, Gioscia-Ryan RA, Murphy MP, Seals DR. Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults. Hypertension (Dallas, Tex. : 1979). PMID 29661838 DOI: 10.1161/Hypertensionaha.117.10787  1
2018 Kohlhauer M, Dawkins S, Costa ASH, Lee R, Young T, Pell VR, Choudhury RP, Banning AP, Kharbanda RK, Saeb-Parsy K, Murphy MP, Frezza C, Krieg T, Channon KM. Metabolomic Profiling in Acute ST-Segment-Elevation Myocardial Infarction Identifies Succinate as an Early Marker of Human Ischemia-Reperfusion Injury. Journal of the American Heart Association. 7. PMID 29626151 DOI: 10.1161/JAHA.117.007546  1
2018 Fazakerley DJ, Minard AY, Krycer JR, Thomas KC, Stöckli J, Harney DJ, Burchfield JG, Maghzal GJ, Caldwell ST, Hartley RC, Stocker R, Murphy MP, James DE. Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation. The Journal of Biological Chemistry. PMID 29599292 DOI: 10.1074/jbc.RA117.001254  1
2018 Wang SK, Murphy MP. Immune Modulation as a Treatment for Abdominal Aortic Aneurysms. Circulation Research. 122: 925-927. PMID 29599276 DOI: 10.1161/CIRCRESAHA.118.312870  1
2018 Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, ... Murphy MP, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. PMID 29590092 DOI: 10.1038/nature25986  1
2018 Sidlauskaite E, Gibson JW, Megson IL, Whitfield PD, Tovmasyan A, Batinic-Haberle I, Murphy MP, Moult PR, Cobley JN. Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning. Redox Biology. 16: 344-351. PMID 29587245 DOI: 10.1016/j.redox.2018.03.012  0.01
2018 Chong KL, Chalmers BA, Cullen JK, Kaur A, Kolanowski JL, Morrow BJ, Fairfull-Smith KE, Lavin MJ, Barnett NL, New EJ, Murphy MP, Bottle SE. Pro-fluorescent mitochondria-targeted real-time responsive redox probes synthesised from carboxy isoindoline nitroxides: Sensitive probes of mitochondrial redox status in cells. Free Radical Biology & Medicine. PMID 29567391 DOI: 10.1016/J.Freeradbiomed.2018.03.008  0.01
2018 Wang SK, Green LA, Gutwein AR, Drucker NA, Babbey CM, Gupta AK, Fajardo A, Motaganahalli RL, Wilson MG, Murphy MP. Ethnic minorities with critical limb ischemia derive equal amputation risk reduction from autologous cell therapy compared with whites. Journal of Vascular Surgery. PMID 29503004 DOI: 10.1016/j.jvs.2017.11.088  1
2018 Bundgaard A, James AM, Joyce W, Murphy MP, Fago A. Suppression of reactive oxygen species generation in heart mitochondria from anoxic turtles: the role of complex I S-nitrosation. The Journal of Experimental Biology. PMID 29496783 DOI: 10.1242/jeb.174391  1
2018 Peruzzotti-Jametti L, Bernstock JD, Vicario N, Costa ASH, Kwok CK, Leonardi T, Booty LM, Bicci I, Balzarotti B, Volpe G, Mallucci G, Manferrari G, Donegà M, Iraci N, Braga A, ... Murphy MP, et al. Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation. Cell Stem Cell. PMID 29478844 DOI: 10.1016/J.Stem.2018.01.020  1
2018 Wang SK, Murphy MP, Gutwein AR, Drucker NA, Dalsing MC, Motaganahalli RL, Lemmon GW, Akingba AG. Perioperative Outcomes are Adversely Affected by Poor Pretransfer Adherence to Acute Limb Ischemia Practice Guidelines. Annals of Vascular Surgery. PMID 29477682 DOI: 10.1016/j.avsg.2017.11.050  1
2018 Deshwal S, Forkink M, Hu CH, Buonincontri G, Antonucci S, Di Sante M, Murphy MP, Paolocci N, Mochly-Rosen D, Krieg T, Di Lisa F, Kaludercic N. Monoamine oxidase-dependent endoplasmic reticulum-mitochondria dysfunction and mast cell degranulation lead to adverse cardiac remodeling in diabetes. Cell Death and Differentiation. PMID 29459772 DOI: 10.1038/S41418-018-0071-1  1
2018 Wilson RJ, Drake JC, Cui D, Lewellen BM, Fisher CC, Zhang M, Kashatus DF, Palmer LA, Murphy MP, Yan Z. Mitochondrial protein S-nitrosation protects against ischemia reperfusion-induced denervation at neuromuscular junction in skeletal muscle. Free Radical Biology & Medicine. PMID 29432799 DOI: 10.1016/j.freeradbiomed.2018.02.006  0.01
2018 Wang SK, Gutwein AR, Drucker NA, Murphy MP, Fajardo A, Dalsing MC, Motaganahalli RL, Lemmon GW. Cryopreserved Homografts in Infected Infrainguinal Fields are Associated with Frequent Reinterventions and Poor Amputation Free Survival. Annals of Vascular Surgery. PMID 29421428 DOI: 10.1016/j.avsg.2017.10.032  1
2018 Ribeiro Junior RF, Dabkowski ER, Shekar KC, O Connell KA, Hecker PA, Murphy MP. MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload. Free Radical Biology & Medicine. 117: 18-29. PMID 29421236 DOI: 10.1016/j.freeradbiomed.2018.01.012  0.01
2018 Pak O, Scheibe S, Esfandiary A, Gierhardt M, Sydykov A, Logan A, Fysikopoulos A, Veit F, Hecker M, Kroschel F, Quanz K, Erb A, Schäfer K, Fassbinder M, Alebrahimdehkordi N, ... Murphy MP, et al. Impact of the mitochondria-targeted antioxidant MitoQ on hypoxia-induced pulmonary hypertension. The European Respiratory Journal. PMID 29419444 DOI: 10.1183/13993003.01024-2017  1
2018 Wang SK, Green LA, Gutwein AR, Gupta AK, Babbey CM, Motaganahalli RL, Fajardo A, Murphy MP. Osteopontin may be a driver of abdominal aortic aneurysm formation. Journal of Vascular Surgery. PMID 29402664 DOI: 10.1016/j.jvs.2017.10.068  1
2018 Wang SK, Gutwein AR, Gupta AK, Lemmon GW, Sawchuk AP, Motaganahalli RL, Murphy MP, Fajardo A. Institutional experience with the Zenith Fenestrated aortic stent graft. Journal of Vascular Surgery. PMID 29395428 DOI: 10.1016/j.jvs.2017.11.063  1
2018 Wang SK, Green LA, Drucker NA, Motaganahalli RL, Fajardo A, Murphy MP. Rationale and design of the Clinical and Histologic Analysis of Mesenchymal Stromal Cells in AmPutations (CHAMP) trial investigating the therapeutic mechanism of mesenchymal stromal cells in the treatment of critical limb ischemia. Journal of Vascular Surgery. PMID 29395424 DOI: 10.1016/j.jvs.2017.09.057  1
2018 Secinaro MA, Fortner KA, Dienz O, Logan A, Murphy MP, Anathy V, Boyson JE, Budd RC. Glycolysis promotes caspase-3 activation in lipid rafts in T cells. Cell Death & Disease. 9: 62. PMID 29352186 DOI: 10.1038/s41419-017-0099-z  1
2018 Park M, Nishimura T, Naudi A, Young T, Pamplona R, Hartley R, Murphy M, Krieg T. MitoGamide ameliorates diabetic cardiomyopathy by scavenging mitochondrial dicarbonyls in type 1 diabetic Akita mice Journal of Molecular and Cellular Cardiology. 120: 27. DOI: 10.1016/J.Yjmcc.2018.05.086  0.01
2018 Sidlauskaite E, Megson IL, Whitfield PD, Batinic-Haberle I, Murphy MP, Cobley JN, Moult PR. ROS regulate developmental and pathological denervation in vivo Free Radical Biology and Medicine. 120: S30-S31. DOI: 10.1016/j.freeradbiomed.2018.04.106  0.01
2018 Murphy M. Exploring mitochondrial free radical production in health and disease Free Radical Biology and Medicine. 120: S2. DOI: 10.1016/J.Freeradbiomed.2018.04.013  0.01
2018 Pak O, Hüttemann M, Scheibe S, Gierhardt M, Sydykov A, Schäfer K, Ghofrani H, Schermuly R, Murphy M, Grossman L, Weissmann N, Sommer N. The role of Mitochondrial Superoxide Release in Acute and Chronic Hypoxia Sensing and Signaling of the Pulmonary vasculature Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1859: e90-e91. DOI: 10.1016/J.Bbabio.2018.09.268  0.01
2017 Wang SK, Gutwein AR, Casciani T, Murphy MP, Lemmon GW. Staged endovascular repair of an abdominal aortic aneurysm adjacent to a chronic high-flow iliocaval traumatic arteriovenous fistula. Journal of Vascular Surgery Cases and Innovative Techniques. 3: 247-250. PMID 29349437 DOI: 10.1016/j.jvscit.2017.10.004  1
2017 Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, ... ... Murphy MP, et al. Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases. Cell Death and Differentiation. PMID 29229998 DOI: 10.1038/S41418-017-0020-4  1
2017 Wang SK, Lemmon GW, Drucker NA, Motaganahalli RL, Dalsing MC, Gutwein AR, Gray BW, Murphy MP. Results of nonoperative management of acute limb ischemia in infants. Journal of Vascular Surgery. PMID 29224940 DOI: 10.1016/j.jvs.2017.09.036  1
2017 Wang SK, Xie J, Green LA, McCready RA, Motaganahalli RL, Fajardo A, Babbey CC, Murphy MP. TSG-6 is highly expressed in human abdominal aortic aneurysms. The Journal of Surgical Research. 220: 311-319. PMID 29180197 DOI: 10.1016/J.Jss.2017.06.078  1
2017 Ward MS, Flemming NB, Gallo LA, Fotheringham AK, McCarthy DA, Zhuang A, Tang PH, Borg DJ, Shaw H, Harvie B, Briskey DR, Roberts LA, Plan MR, Murphy MP, Hodson MP, et al. Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes. Scientific Reports. 7: 15190. PMID 29123192 DOI: 10.1038/s41598-017-15589-x  0.01
2017 Gioscia-Ryan RA, Battson ML, Cuevas LM, Eng JS, Murphy MP, Seals DR. Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00670.2017. PMID 29074712 DOI: 10.1152/Japplphysiol.00670.2017  1
2017 Frankenreiter S, Bednarczyk P, Kniess A, Bork N, Straubinger J, Koprowski P, Wrzosek A, Mohr E, Logan A, Murphy MP, Gawaz M, Krieg T, Szewczyk A, Nikolaev VO, Ruth P, et al. cGMP-Elevating Compounds and Ischemic Conditioning Provide Cardioprotection Against Ischemia and Reperfusion Injury via Cardiomyocyte-Specific BK Channels. Circulation. PMID 29051185 DOI: 10.1161/Circulationaha.117.028723  1
2017 Yu EPK, Reinhold J, Yu H, Starks L, Uryga AK, Foote K, Finigan A, Figg N, Pung YF, Logan A, Murphy MP, Bennett M. Mitochondrial Respiration Is Reduced in Atherosclerosis, Promoting Necrotic Core Formation and Reducing Relative Fibrous Cap Thickness. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28970293 DOI: 10.1161/ATVBAHA.117.310042  1
2017 Wang SK, Green LA, Gutwein AR, Drucker NA, Motaganahalli RL, Fajardo A, Babbey CC, Murphy MP. Rationale and Design of the ARREST Trial Investigating Mesenchymal Stem Cells in the Treatment of Small AAA. Annals of Vascular Surgery. PMID 28916304 DOI: 10.1016/j.avsg.2017.08.044  1
2017 Shchepinova MM, Cairns AG, Prime TA, Logan A, James AM, Hall AR, Vidoni S, Arndt S, Caldwell ST, Prag HA, Pell VR, Krieg T, Mulvey JF, Yadav P, Cobley JN, ... Murphy MP, et al. MitoNeoD: A Mitochondria-Targeted Superoxide Probe. Cell Chemical Biology. PMID 28890317 DOI: 10.1016/j.chembiol.2017.08.003  1
2017 Phillips TJ, Scott H, Menassa DA, Bignell AL, Sood A, Morton JS, Akagi T, Azuma K, Rogers MF, Gilmore CE, Inman GJ, Grant S, Chung Y, Aljunaidy MM, Cooke CL, ... ... Murphy MP, et al. Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development. Scientific Reports. 7: 9079. PMID 28831049 DOI: 10.1038/s41598-017-06300-1  1
2017 Rivera-Barahona A, Alonso-Barroso E, Pérez B, Murphy MP, Richard E, Desviat LR. Treatment with antioxidants ameliorates oxidative damage in a mouse model of propionic acidemia. Molecular Genetics and Metabolism. PMID 28774709 DOI: 10.1016/j.ymgme.2017.07.009  1
2017 Chouchani ET, James AM, Methner C, Pell VR, Prime TA, Erikson BK, Forkink M, Lau GY, Bright TP, Menger KE, Fearnley IM, Krieg T, Murphy MP. Identification and Quantification of Protein S-nitrosation by Nitrite in the Mouse Heart during Ischemia. The Journal of Biological Chemistry. PMID 28710281 DOI: 10.1074/jbc.M117.798744  1
2017 Green L, Ofstein RH, Rapp B, Saadatzadeh MR, Bhavsar JR, Fajardo A, Dalsing MC, Ingram DA, Murphy MP. Adult venous endothelium is a niche for highly proliferative and vasculogenic endothelial colony-forming cells. Journal of Vascular Surgery. PMID 28655551 DOI: 10.1016/j.jvs.2016.11.059  1
2017 Kazak L, Chouchani ET, Stavrovskaya IG, Lu GZ, Jedrychowski MP, Egan DF, Kumari M, Kong X, Erickson BK, Szpyt J, Rosen ED, Murphy MP, Kristal BS, Gygi SP, Spiegelman BM. UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630339 DOI: 10.1073/Pnas.1705406114  1
2017 Liu X, Murphy MP, Xing W, Wu H, Zhang R, Sun H. Mitochondria-targeted antioxidant MitoQ reduced renal damage caused by ischemia-reperfusion injury in rodent kidneys: Longitudinal observations of T2 -weighted imaging and dynamic contrast-enhanced MRI. Magnetic Resonance in Medicine. PMID 28608403 DOI: 10.1002/mrm.26772  0.01
2017 Sompol P, Furman JL, Pleiss MM, Kraner SD, Artiushin IA, Batten SR, Quintero JE, Simmerman LA, Beckett TL, Lovell MA, Murphy MP, Gerhardt GA, Norris CM. Calcineurin/NFAT signaling in activated astrocytes drives network hyperexcitability in Aβ-bearing mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28559377 DOI: 10.1523/Jneurosci.0877-17.2017  1
2017 Formentini L, Santacatterina F, Núñez de Arenas C, Stamatakis K, López-Martínez D, Logan A, Fresno M, Smits R, Murphy MP, Cuezva JM. Mitochondrial ROS Production Protects the Intestine from Inflammation through Functional M2 Macrophage Polarization. Cell Reports. 19: 1202-1213. PMID 28494869 DOI: 10.1016/j.celrep.2017.04.036  1
2017 Park SY, Kwon OS, Andtbacka RHI, Hyngstrom JR, Reese V, Murphy MP, Richardson RS. Age-related endothelial dysfunction in human skeletal muscle feed arteries: The role of free radicals derived from mitochondria in the vasculature. Acta Physiologica (Oxford, England). PMID 28493603 DOI: 10.1111/apha.12893  0.01
2017 Wang SK, Murphy MP. Getting A Leg Up on Cell Therapy for Critical Limb Ischemia. Circulation Research. 120: 1227-1228. PMID 28408447 DOI: 10.1161/CIRCRESAHA.117.310864  1
2017 Wang SK, Green LA, Motaganahalli RL, Wilson MG, Fajardo A, Murphy MP. Rationale and design of the MarrowStim PAD Kit for the Treatment of Critical Limb Ischemia in Subjects with Severe Peripheral Arterial Disease (MOBILE) trial investigating autologous bone marrow cell therapy for critical limb ischemia. Journal of Vascular Surgery. PMID 28390770 DOI: 10.1016/j.jvs.2017.01.054  1
2017 Logan A, Murphy MP. Using chemical biology to assess and modulate mitochondria: progress and challenges. Interface Focus. 7: 20160151. PMID 28382206 DOI: 10.1098/rsfs.2016.0151  1
2017 Hoogewijs K, James AM, Smith RA, Abendroth F, Gait MJ, Murphy MP, Lightowlers RN. ClickIn: a flexible protocol for quantifying mitochondrial uptake of nucleobase derivatives. Interface Focus. 7: 20160117. PMID 28382203 DOI: 10.1098/rsfs.2016.0117  1
2017 Vilaseca M, García-Calderó H, Lafoz E, Ruart M, López-Sanjurjo CI, Murphy MP, Deulofeu R, Bosch J, Hernández-Gea V, Gracia-Sancho J, García-Pagán JC. Mitochondria-targeted antioxidant mitoquinone deactivates human and rat HSC and reduces portal hypertension in cirrhotic rats. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 28371136 DOI: 10.1111/liv.13436  0.01
2017 van Leeuwen LA, Hinchy EC, Murphy MP, Robb EL, Cochemé HM. Click-PEGylation - a mobility shift approach to assess the redox state of cysteines in candidate proteins. Free Radical Biology & Medicine. PMID 28366801 DOI: 10.1016/j.freeradbiomed.2017.03.037  1
2017 Tsuchiya Y, Peak-Chew S, Newell C, Miller-Aidoo S, Mangal S, Zhyvoloup A, Baković J, Malanchuk O, Pereira G, Kotiadis V, Szabadkai G, Duchen M, Campbell M, Rodriguez Cuenca S, Vidal-Puig A, ... Murphy MP, et al. Protein CoAlation: A Redox-Regulated Protein Modification by Coenzyme Ain Mammalian Cells. The Biochemical Journal. PMID 28341808 DOI: 10.1042/BCJ20170129  1
2017 Arndt S, Baeza-Garza CD, Logan A, Rosa T, Wedmann R, Prime TA, Martin JL, Saeb-Parsy K, Krieg T, Filipovic MR, Hartley RC, Murphy MP. Assessment of H2S in vivo Using the Newly Developed Mitochondria-Targeted Mass Spectrometry Probe MitoA. The Journal of Biological Chemistry. PMID 28320864 DOI: 10.1074/jbc.M117.784678  1
2017 James AM, Hoogewijs K, Logan A, Hall AR, Ding S, Fearnley IM, Murphy MP. Non-enzymatic N-acetylation of Lysine Residues by AcetylCoA Often Occurs via a Proximal S-acetylated Thiol Intermediate Sensitive to Glyoxalase II. Cell Reports. 18: 2105-2112. PMID 28249157 DOI: 10.1016/j.celrep.2017.02.018  1
2017 Perin EC, Murphy MP, March KL, Bolli R, Loughran J, Yang PC, Leeper NJ, Dalman RL, Alexander JQ, Henry TD, Traverse JH, Pepine CJ, Anderson RD, Berceli S, Willerson JT, et al. Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN Patients with Intermittent Claudication Injected with ALDH Bright Cells (PACE) Trial. Circulation. PMID 28209728 DOI: 10.1161/Circulationaha.116.025707  1
2017 Yrineo AA, Adelsperger AR, Durkes AC, Distasi MR, Voytik-Harbin SL, Murphy MP, Goergen CJ. Murine ultrasound-guided transabdominal para-aortic injections of self-assembling type I collagen oligomers. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28126527 DOI: 10.1016/j.jconrel.2016.12.045  1
2017 Mulvey J, Logan A, Arndt S, Pell V, Caldwell S, Hartley R, Murphy M, Krieg T. 208 Cardioprotection by the mitochondria-targeted superoxide generator mitoparaquat in a murine model of acute myocardial ischaemia reperfusion injury Heart. 103: A138.3-A139. DOI: 10.1136/Heartjnl-2017-311726.206  0.01
2017 Reinhold J, Uryga AK, Murphy MP, Bennett MR. Mitochondrial function in human atherosclerotic plaques and effects of atherogenic lipids on vascular smooth muscle cells The Lancet. 389: S82. DOI: 10.1016/S0140-6736(17)30478-6  0.01
2017 Scheibe S, Pak O, Esfandiary A, Sydykov A, Murphy M, Weissmann N, Sommer N. The role of mitochondrial reactive oxygen species in the response of the pulmonary vasculature to hypoxia and right heart remodeling Free Radical Biology and Medicine. 108: S74. DOI: 10.1016/J.Freeradbiomed.2017.04.250  0.01
2016 Latorre-Pellicer A, Moreno-Loshuertos R, Lechuga-Vieco AV, Sánchez-Cabo F, Torroja C, Acín-Pérez R, Calvo E, Aix E, González-Guerra A, Logan A, Bernad-Miana ML, Romanos E, Cruz R, Cogliati S, Sobrino B, ... ... Murphy MP, et al. Corrigendum: Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing. Nature. PMID 27926738 DOI: 10.1038/nature20773  1
2016 Murphy MP. Understanding and preventing mitochondrial oxidative damage. Biochemical Society Transactions. 44: 1219-1226. PMID 27911703 DOI: 10.1042/BST20160108  0.01
2016 Buskiewicz IA, Montgomery T, Yasewicz EC, Huber SA, Murphy MP, Hartley RC, Kelly R, Crow MK, Perl A, Budd RC, Koenig A. Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus. Science Signaling. 9: ra115. PMID 27899525 DOI: 10.1126/scisignal.aaf1933  1
2016 Escribano-Lopez I, Diaz-Morales N, Rovira-Llopis S, de Marañon AM, Orden S, Alvarez A, Bañuls C, Rocha M, Murphy MP, Hernandez-Mijares A, Victor VM. The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients. Redox Biology. 10: 200-205. PMID 27810734 DOI: 10.1016/j.redox.2016.10.017  1
2016 Lopez-Fabuel I, Le Douce J, Logan A, James AM, Bonvento G, Murphy MP, Almeida A, Bolaños JP. Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799543 DOI: 10.1073/Pnas.1613701113  1
2016 Jalloh I, Helmy A, Howe DJ, Shannon RJ, Grice P, Mason A, Gallagher CN, Stovell MG, van der Heide S, Murphy MP, Pickard JD, Menon DK, Carpenter TA, Hutchinson PJ, Carpenter KL. Focally perfused succinate potentiates brain metabolism in head injury patients. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27798266 DOI: 10.1177/0271678X16672665  1
2016 Murphy MP. Mitochondrial Diseases: Shortcuts to Therapies and Therapeutic Shortcuts. Molecular Cell. 64: 5-6. PMID 27716487 DOI: 10.1016/j.molcel.2016.09.022  0.01
2016 Kim BJ, Valsangkar NP, Liang TW, Murphy MP, Zimmers TA, Bell TM, Davies MG, Koniaris LG. Impact of Integrated Vascular Fellowships on Academic Productivity within Vascular Surgery Divisions. Annals of Vascular Surgery. PMID 27671458 DOI: 10.1016/j.avsg.2016.06.031  1
2016 Mills EL, Kelly B, Logan A, Costa AS, Varma M, Bryant CE, Tourlomousis P, Däbritz JH, Gottlieb E, Latorre I, Corr SC, McManus G, Ryan D, Jacobs HT, Szibor M, ... Murphy MP, et al. Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages. Cell. PMID 27667687 DOI: 10.1016/j.cell.2016.08.064  1
2016 Golledge J, Norman PE, Murphy MP, Dalman RL. Challenges and opportunities in limiting abdominal aortic aneurysm growth. Journal of Vascular Surgery. PMID 27641464 DOI: 10.1016/j.jvs.2016.08.003  0.01
2016 Bolaños JP, Cadenas E, Duchen MR, Hampton MB, Mann GE, Murphy MP. Introduction to Special Issue on Mitochondrial Redox Signaling in Health and Disease. Free Radical Biology & Medicine. PMID 27502830 DOI: 10.1016/J.Freeradbiomed.2016.08.004  1
2016 Xie J, Jones TJ, Feng D, Cook TG, Jester AA, Yi R, Jawed YT, Babbey C, March KL, Murphy MP. Human Adipose-Derived Stem Cells Suppress Elastase-Induced Murine Abdominal Aortic Inflammation and Aneurysm Expansion Through Paracrine Factors. Cell Transplantation. PMID 27436185 DOI: 10.3727/096368916X692212  1
2016 Stucki DM, Ruegsegger C, Steiner S, Radecke J, Murphy MP, Zuber B, Saxena S. Mitochondrial impairments contribute to Spinocerebellar ataxia type 1 progression and can be ameliorated by the mitochondria-targeted antioxidant MitoQ. Free Radical Biology & Medicine. PMID 27394174 DOI: 10.1016/J.Freeradbiomed.2016.07.005  1
2016 Latorre-Pellicer A, Moreno-Loshuertos R, Lechuga-Vieco AV, Sánchez-Cabo F, Torroja C, Acín-Pérez R, Calvo E, Aix E, González-Guerra A, Logan A, Bernad-Miana ML, Romanos E, Cruz R, Cogliati S, Sobrino B, ... Murphy MP, et al. Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing. Nature. PMID 27383793 DOI: 10.1038/nature18618  1
2016 Stoyanovsky DA, Jiang J, Murphy MP, Epperly M, Zhang X, Li S, Greenberger J, Kagan V, Bayır H. Correction to "Design and Synthesis of a Mitochondria-Targeted Mimic of Glutathione Peroxidase, MitoEbselen-2, as a Radiation Mitigator". Acs Medicinal Chemistry Letters. 7: 653-654. PMID 27326344 DOI: 10.1021/Acsmedchemlett.6B00212  1
2016 Bhattacharjee A, Yang H, Duffy M, Robinson E, Conrad-Antoville A, Lu YW, Capps T, Braiterman LT, Wolfgang MJ, Murphy MP, Yi L, Kaler SG, Lutsenko S, Ralle M. Activity of Menkes Disease Protein ATP7A is Essential for Redox Balance in Mitochondria. The Journal of Biological Chemistry. PMID 27226607 DOI: 10.1074/Jbc.M116.727248  1
2016 Pell VR, Chouchani ET, Frezza C, Murphy MP, Krieg T. Succinate metabolism: a new therapeutic target for myocardial reperfusion injury. Cardiovascular Research. PMID 27194563 DOI: 10.1093/cvr/cvw100  1
2016 Rehman H, Liu Q, Krishnasamy Y, Shi Z, Ramshesh VK, Haque K, Schnellmann RG, Murphy MP, Lemasters JJ, Rockey DC, Zhong Z. The mitochondria-targeted antioxidant MitoQ attenuates liver fibrosis in mice. International Journal of Physiology, Pathophysiology and Pharmacology. 8: 14-27. PMID 27186319  0.01
2016 Rokitskaya TI, Murphy MP, Skulachev VP, Antonenko YN. Ubiquinol and plastoquinol triphenylphosphonium conjugates can carry electrons through phospholipid membranes. Bioelectrochemistry (Amsterdam, Netherlands). 111: 23-30. PMID 27182824 DOI: 10.1016/J.Bioelechem.2016.04.009  1
2016 Lovell MA, Lynn BC, Fister S, Bradley-Whitman M, Murphy MP, Beckett TL, Norris CM. A Novel Small Molecule Modulator of Amyloid Pathology. Journal of Alzheimer's Disease : Jad. PMID 27163808 DOI: 10.3233/Jad-151160  1
2016 Hoogeweijs K, James A, Smith R, Gait M, Lightowlers R, Murphy M. Assessing the Delivery of Molecules to the Mitochondrial Matrix Using Click Chemistry. Chembiochem : a European Journal of Chemical Biology. PMID 27124570 DOI: 10.1002/cbic.201600188  1
2016 Stromdahl EY, Nadolny RM, Gibbons JA, Auckland LD, Vince MA, Elkins CE, Murphy MP, Hickling GJ, Eshoo MW, Carolan HE, Crowder CD, Pilgard MA, Hamer SA. Erratum for Stromdahl et al., Borrelia burgdorferi Not Confirmed in Human-Biting Amblyomma americanum Ticks from the Southeastern United States. Journal of Clinical Microbiology. 54: 1406. PMID 27114565 DOI: 10.1128/Jcm.00527-16  1
2016 Gallego-Villar L, Rivera-Barahona A, Cuevas-Martín C, Guenzel A, Pérez B, Barry MA, Murphy MP, Logan A, Gonzalez-Quintana A, Martín MA, Medina S, Gil-Izquierdo A, Cuezva JM, Richard E, Desviat LR. In vivo evidence of mitochondrial dysfunction and altered redox homeostasis in a genetic mouse model of propionic acidemia: Implications for the pathophysiology of this disorder. Free Radical Biology & Medicine. 96: 1-12. PMID 27083476 DOI: 10.1016/J.Freeradbiomed.2016.04.007  1
2016 Green LA, Njoku V, Mund JA, Case J, Yoder MC, Murphy MP, Clauss M. Endogenous Transmembrane TNF-Alpha Protects Against Premature Senescence in Endothelial Colony Forming Cells. Circulation Research. PMID 27076598 DOI: 10.1161/Circresaha.116.308332  1
2016 Scialò F, Sriram A, Fernández-Ayala D, Gubina N, Lõhmus M, Nelson G, Logan A, Cooper HM, Navas P, Enríquez JA, Murphy MP, Sanz A. Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan. Cell Metabolism. 23: 725-34. PMID 27076081 DOI: 10.1016/j.cmet.2016.03.009  1
2016 Liang TW, Jester A, Motaganahalli RL, Wilson MG, G'Sell P, Akingba GA, Fajardo A, Murphy MP. Autologous bone marrow mononuclear cell therapy for critical limb ischemia is effective and durable. Journal of Vascular Surgery. PMID 27021379 DOI: 10.1016/j.jvs.2016.01.022  1
2016 Liou GY, Döppler H, DelGiorno KE, Zhang L, Leitges M, Crawford HC, Murphy MP, Storz P. Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions. Cell Reports. PMID 26947075 DOI: 10.1016/J.Celrep.2016.02.029  1
2016 Pell VR, Chouchani ET, Murphy MP, Brookes PS, Krieg T. Moving Forwards by Blocking Back-Flow: The Yin and Yang of MI Therapy. Circulation Research. 118: 898-906. PMID 26941425 DOI: 10.1161/Circresaha.115.306569  1
2016 Coudray C, Fouret G, Lambert K, Ferreri C, Rieusset J, Blachnio-Zabielska A, Lecomte J, Ebabe Elle R, Badia E, Murphy MP, Feillet-Coudray C. A mitochondrial-targeted ubiquinone modulates muscle lipid profile and improves mitochondrial respiration in obesogenic diet-fed rats. The British Journal of Nutrition. 1-12. PMID 26856891 DOI: 10.1017/S0007114515005528  1
2016 Chouchani ET, Pell VR, James AM, Work LM, Saeb-Parsy K, Frezza C, Krieg T, Murphy MP. A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury. Cell Metabolism. PMID 26777689 DOI: 10.1016/j.cmet.2015.12.009  1
2016 Smith MR, Vayalil PK, Zhou F, Benavides GA, Beggs RR, Golzarian H, Nijampatnam B, Oliver PG, Smith RA, Murphy MP, Velu SE, Landar A. Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels. Redox Biology. 8: 136-148. PMID 26774751 DOI: 10.1016/J.Redox.2016.01.002  1
2016 Murphy MP, Caraher E. Current and Emerging Therapies for the Treatment of Cystic Fibrosis or Mitigation of Its Symptoms. Drugs in R&D. PMID 26747453 DOI: 10.1007/s40268-015-0121-9  1
2016 Murphy MP. Irish civil society: rearranging the deckchairs on the Titanic? A case study of fighting Irish social security retrenchment Journal of Civil Society. 12: 17-32. DOI: 10.1080/17448689.2016.1117244  1
2016 Platt TL, Beckett TL, Kohler K, Niedowicz DM, Murphy MP. Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease Neuroscience. 315: 162-174. DOI: 10.1016/j.neuroscience.2015.12.011  1
2016 Scheibe S, Pak O, Murphy MP, Ghofrani HA, Seeger W, Grimminger F, Schermuly RT, Weissmann N, Sommer N. Mitochondria-targeted antioxidant MitoQ intercepts superoxide radical formation under acute hypoxia: Evaluation of the oxidative stress in murine pulmonary arterial smooth muscle cells by electron paramagnetic resonance spectroscopy Free Radical Biology and Medicine. 96: S50. DOI: 10.1016/j.freeradbiomed.2016.04.106  0.01
2016 Murphy MP, Corriveau RA, Wilcock DM. Vascular contributions to cognitive impairment and dementia (VCID) Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1862: 857-859. DOI: 10.1016/j.bbadis.2016.02.010  1
2015 Menger KE, James AM, Cochemé HM, Harbour ME, Chouchani ET, Ding S, Fearnley IM, Partridge L, Murphy MP. Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster. Cell Reports. 13: 1285. PMID 28873344 DOI: 10.1016/j.celrep.2015.10.048  1
2015 Logan A, Pell VR, Shaffer KJ, Evans C, Stanley NJ, Robb EL, Prime TA, Chouchani ET, Cochemé HM, Fearnley IM, Vidoni S, James AM, Porteous CM, Partridge L, Krieg T, ... ... Murphy MP, et al. Assessing the Mitochondrial Membrane Potential in Cells and In Vivo using Targeted Click Chemistry and Mass Spectrometry. Cell Metabolism. PMID 26712463 DOI: 10.1016/j.cmet.2015.11.014  1
2015 Santini E, Turner KL, Ramaraj AB, Murphy MP, Klann E, Kaphzan H. Mitochondrial Superoxide Contributes to Hippocampal Synaptic Dysfunction and Memory Deficits in Angelman Syndrome Model Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 16213-16220. PMID 26658871 DOI: 10.1523/Jneurosci.2246-15.2015  1
2015 Woodell-May JE, Tan ML, King WJ, Swift MJ, Welch ZR, Murphy MP, McKale JM. Characterization of the Cellular Output of a Point-of-Care Device and the Implications for Addressing Critical Limb Ischemia. Bioresearch Open Access. 4: 417-424. PMID 26634187 DOI: 10.1089/biores.2015.0006  0.01
2015 Nussbaumer M, Asara JM, Teplytska L, Murphy MP, Logan A, Turck CW, Filiou MD. Selective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26567514 DOI: 10.1038/npp.2015.341  1
2015 Jameson VJ, Cochemé HM, Logan A, Hanton LR, Smith RA, Murphy MP. Synthesis of triphenylphosphonium vitamin E derivatives as mitochondria-targeted antioxidants. Tetrahedron. 71: 8444-8453. PMID 26549895 DOI: 10.1016/j.tet.2015.09.014  1
2015 Robb EL, Gawel JM, Aksentijević D, Cochemé HM, Stewart TS, Shchepinova MM, Qiang H, Prime TA, Bright TP, James AM, Shattock MJ, Senn HM, Hartley RC, Murphy MP. Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat. Free Radical Biology & Medicine. 89: 883-894. PMID 26454075 DOI: 10.1016/j.freeradbiomed.2015.08.021  1
2015 Hirschey MD, DeBerardinis RJ, Diehl AM, Drew JE, Frezza C, Green MF, Jones LW, Ko YH, Le A, Lea MA, Locasale JW, Longo VD, Lyssiotis CA, McDonnell E, Mehrmohamadi M, ... Murphy MP, et al. Dysregulated metabolism contributes to oncogenesis. Seminars in Cancer Biology. PMID 26454069 DOI: 10.1016/j.semcancer.2015.10.002  1
2015 Finichiu PG, Larsen DS, Evans C, Larsen L, Bright TP, Robb EL, Trnka J, Prime TA, James AM, Smith RA, Murphy MP. A mitochondria-targeted derivative of ascorbate: MitoC. Free Radical Biology & Medicine. 89: 668-678. PMID 26453920 DOI: 10.1016/j.freeradbiomed.2015.07.160  1
2015 Murphy MP, Staffileno BA, Carlson E. Collaboration Among DNP- and PhD-Prepared Nurses: Opportunity to Drive Positive Change. Journal of Professional Nursing : Official Journal of the American Association of Colleges of Nursing. 31: 388-94. PMID 26428343 DOI: 10.1016/J.Profnurs.2015.03.001  1
2015 Murphy MP, Caraher E. Residence in biofilms allows Burkholderia cepacia complex (Bcc) bacteria to evade the antimicrobial activities of neutrophil-like dHL60 cells. Pathogens and Disease. 73: ftv069. PMID 26371179 DOI: 10.1093/femspd/ftv069  1
2015 Murphy MP. Redox Modulation by Reversal of the Mitochondrial Nicotinamide Nucleotide Transhydrogenase. Cell Metabolism. 22: 363-5. PMID 26331603 DOI: 10.1016/j.cmet.2015.08.012  1
2015 Willems PH, Rossignol R, Dieteren CE, Murphy MP, Koopman WJ. Redox Homeostasis and Mitochondrial Dynamics. Cell Metabolism. 22: 207-18. PMID 26166745 DOI: 10.1016/j.cmet.2015.06.006  1
2015 Kelly B, Tannahill GM, Murphy MP, O'Neill LA. Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages. The Journal of Biological Chemistry. 290: 20348-59. PMID 26152715 DOI: 10.1074/jbc.M115.662114  1
2015 Dare AJ, Logan A, Prime TA, Rogatti S, Goddard M, Bolton EM, Bradley JA, Pettigrew GJ, Murphy MP, Saeb-Parsy K. The mitochondria-targeted anti-oxidant MitoQ decreases ischemia-reperfusion injury in a murine syngeneic heart transplant model. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. PMID 26140808 DOI: 10.1016/j.healun.2015.05.007  1
2015 Chang TW, Gracon AS, Murphy MP, Wilkes DS. Exploring autoimmunity in the pathogenesis of abdominal aortic aneurysms. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00273.2015. PMID 26116712 DOI: 10.1152/Ajpheart.00273.2015  1
2015 Wilcock DM, Hurban J, Helman AM, Sudduth TL, McCarty KL, Beckett TL, Ferrell JC, Murphy MP, Abner EL, Schmitt FA, Head E. Down syndrome individuals with Alzheimer's disease have a distinct neuroinflammatory phenotype compared to sporadic Alzheimer's disease. Neurobiology of Aging. 36: 2468-74. PMID 26103884 DOI: 10.1016/J.Neurobiolaging.2015.05.016  1
2015 Menger KE, James AM, Cochemé HM, Harbour ME, Chouchani ET, Ding S, Fearnley IM, Partridge L, Murphy MP. Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster. Cell Reports. 11: 1856-65. PMID 26095360 DOI: 10.1016/j.celrep.2015.05.033  1
2015 Fouret G, Tolika E, Lecomte J, Bonafos B, Aoun M, Murphy MP, Ferreri C, Chatgilialoglu C, Dubreucq E, Coudray C, Feillet-Coudray C. The mitochondrial-targeted antioxidant, MitoQ, increases liver mitochondrial cardiolipin content in obesogenic diet-fed rats. Biochimica Et Biophysica Acta. 1847: 1025-35. PMID 26028302 DOI: 10.1016/J.Bbabio.2015.05.019  1
2015 Hämäläinen RH, Ahlqvist KJ, Ellonen P, Lepistö M, Logan A, Otonkoski T, Murphy MP, Suomalainen A. mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling. Cell Reports. 11: 1614-24. PMID 26027936 DOI: 10.1016/j.celrep.2015.05.009  1
2015 Cunniff B, Newick K, Nelson KJ, Wozniak AN, Beuschel S, Leavitt B, Bhave A, Butnor K, Koenig A, Chouchani ET, James AM, Haynes AC, Lowther WT, Murphy MP, Shukla A, et al. Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma. Plos One. 10: e0127310. PMID 26011724 DOI: 10.1371/Journal.Pone.0127310  1
2015 Dare AJ, Bolton EA, Pettigrew GJ, Bradley JA, Saeb-Parsy K, Murphy MP. Protection against renal ischemia-reperfusion injury in vivo by the mitochondria targeted antioxidant MitoQ. Redox Biology. 5: 163-168. PMID 25965144 DOI: 10.1016/j.redox.2015.04.008  1
2015 Murphy MP, Caraher E. Mcl-1 is vital for neutrophil survival. Immunologic Research. 62: 225-33. PMID 25929430 DOI: 10.1007/s12026-015-8655-z  1
2015 Huang W, Cash N, Wen L, Szatmary P, Mukherjee R, Armstrong J, Chvanov M, Tepikin AV, Murphy MP, Sutton R, Criddle DN. Effects of the mitochondria-targeted antioxidant mitoquinone in murine acute pancreatitis. Mediators of Inflammation. 2015: 901780. PMID 25878403 DOI: 10.1155/2015/901780  1
2015 Wiegman CH, Michaeloudes C, Haji G, Narang P, Clarke CJ, Russell KE, Bao W, Pavlidis S, Barnes PJ, Kanerva J, Bittner A, Rao N, Murphy MP, Kirkham PA, Chung KF, et al. Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease. The Journal of Allergy and Clinical Immunology. PMID 25828268 DOI: 10.1016/j.jaci.2015.01.046  1
2015 Stromdahl EY, Nadolny RM, Gibbons JA, Auckland LD, Vince MA, Elkins CE, Murphy MP, Hickling GJ, Eshoo MW, Carolan HE, Crowder CD, Pilgard MA, Hamer SA. Borrelia burgdorferi not confirmed in human-biting Amblyomma americanum ticks from the southeastern United States. Journal of Clinical Microbiology. 53: 1697-704. PMID 25788545 DOI: 10.1128/Jcm.03454-14  1
2015 Vayalil PK, Oh JY, Zhou F, Diers AR, Smith MR, Golzarian H, Oliver PG, Smith RA, Murphy MP, Velu SE, Landar A. A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms. Plos One. 10: e0120460. PMID 25785718 DOI: 10.1371/Journal.Pone.0120460  1
2015 Murphy MP, Coke L, Staffileno BA, Robinson JD, Tillotson R. Improving cardiovascular health of underserved populations in the community with Life's Simple 7. Journal of the American Association of Nurse Practitioners. PMID 25776437 DOI: 10.1002/2327-6924.12231  1
2015 Powell RD, Swet JH, Kennedy KL, Huynh TT, Murphy MP, Mckillop IH, Evans SL. MitoQ modulates oxidative stress and decreases inflammation following hemorrhage. The Journal of Trauma and Acute Care Surgery. 78: 573-9. PMID 25710429 DOI: 10.1097/Ta.0000000000000533  1
2015 Galarreta CI, Forbes MS, Thornhill BA, Antignac C, Gubler MC, Nevo N, Murphy MP, Chevalier RL. The swan-neck lesion: proximal tubular adaptation to oxidative stress in nephropathic cystinosis. American Journal of Physiology. Renal Physiology. 308: F1155-66. PMID 25694483 DOI: 10.1152/ajprenal.00591.2014  1
2015 Ameri K, Jahangiri A, Rajah AM, Tormos KV, Nagarajan R, Pekmezci M, Nguyen V, Wheeler ML, Murphy MP, Sanders TA, Jeffrey SS, Yeghiazarians Y, Rinaudo PF, Costello JF, Aghi MK, et al. HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth. Cell Reports. PMID 25683712 DOI: 10.1016/J.Celrep.2015.01.020  1
2015 Tramutola A, Triplett JC, Di Domenico F, Niedowicz DM, Murphy MP, Coccia R, Perluigi M, Butterfield DA. Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD. Journal of Neurochemistry. 133: 739-49. PMID 25645581 DOI: 10.1111/Jnc.13037  1
2015 Booty LM, King MS, Thangaratnarajah C, Majd H, James AM, Kunji ER, Murphy MP. The mitochondrial dicarboxylate and 2-oxoglutarate carriers do not transport glutathione. Febs Letters. 589: 621-8. PMID 25637873 DOI: 10.1016/j.febslet.2015.01.027  1
2015 Sethi M, Joshi SS, Webb RL, Beckett TL, Donohue KD, Murphy MP, O'Hara BF, Duncan MJ. Increased fragmentation of sleep-wake cycles in the 5XFAD mouse model of Alzheimer's disease. Neuroscience. 290: 80-9. PMID 25637807 DOI: 10.1016/J.Neuroscience.2015.01.035  1
2015 Teixeira J, Soares P, Benfeito S, Murphy MP, Oliveira PJ, Borges F. Bridging the gap between nature and antioxidant setbacks: delivering caffeic acid to mitochondria. Methods in Molecular Biology (Clifton, N.J.). 1265: 73-83. PMID 25634268 DOI: 10.1007/978-1-4939-2288-8_6  1
2015 Cairns AG, McQuaker SJ, Murphy MP, Hartley RC. Targeting mitochondria with small molecules: the preparation of MitoB and MitoP as exomarkers of mitochondrial hydrogen peroxide. Methods in Molecular Biology (Clifton, N.J.). 1265: 25-50. PMID 25634265 DOI: 10.1007/978-1-4939-2288-8_3  1
2015 Yancey DM, Guichard JL, Ahmed MI, Zhou L, Murphy MP, Johnson MS, Benavides GA, Collawn J, Darley-Usmar V, Dell'Italia LJ. Cardiomyocyte mitochondrial oxidative stress and cytoskeletal breakdown in the heart with a primary volume overload. American Journal of Physiology. Heart and Circulatory Physiology. 308: H651-63. PMID 25599572 DOI: 10.1152/Ajpheart.00638.2014  1
2015 Jalloh I, Carpenter KL, Grice P, Howe DJ, Mason A, Gallagher CN, Helmy A, Murphy MP, Menon DK, Carpenter TA, Pickard JD, Hutchinson PJ. Glycolysis and the pentose phosphate pathway after human traumatic brain injury: microdialysis studies using 1,2-(13)C2 glucose. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 111-20. PMID 25335801 DOI: 10.1038/Jcbfm.2014.177  1
2015 Murphy MP. Gendering the narrative of the Irish crisis Irish Political Studies. 30: 220-237. DOI: 10.1080/07907184.2015.1022866  1
2015 Cannon B, Murphy MP. Where are the pots and pans? Collective responses in Ireland to neoliberalization in a time of crisis: Learning from latin America Irish Political Studies. 30: 1-19. DOI: 10.1080/07907184.2014.942292  1
2015 Kelly B, Tannahill GM, Murphy MP, O'Neill LAJ. Metformin inhibits the production of reactive oxygen species from NADH: Ubiquinone oxidoreductase to limit induction of interleukin-1β (IL-1β) and boosts interleukin-10 (IL-10) in lipopolysaccharide (LPS)-activated macrophages Journal of Biological Chemistry. 290: 20348-20359. DOI: 10.1074/jbc.M115.662114  1
2015 Nussbaumer M, Asara J, Teplytska L, Murphy M, Landgraf R, Turck C, Filiou M. Mitochondria as pharmacological targets for anxiolytic treatment Pharmacopsychiatry. 48. DOI: 10.1055/s-0035-1557981  0.01
2015 Murphy MP, Staffileno BA, Carlson E. Collaboration Among DNP and PhD-Prepared Nurses: Opportunity to Drive Positive Change Journal of Professional Nursing. DOI: 10.1016/j.profnurs.2015.03.001  1
2015 Arndt S, Baeza-Garza CD, Logan A, Rosa T, Krieg T, Hartley RC, Murphy MP. Determination of the endogenous hydrogen sulphide concentration in vivo using the mitochondria-targeted mass spectrometry probe MitoA Nitric Oxide. 47: S16. DOI: 10.1016/j.niox.2015.02.038  0.01
2015 Stoyanovsky D, Jiang J, Murphy M, Epperly M, Li S, Greenberger J, Kagan V, Bayir H. Mitigation of Irradiation Damage In Vitro and In Vivo by Mitochondrial Targeted Glutathione Peroxidase 4 Mimic Mito-Ebselen International Journal of Radiation Oncology*Biology*Physics. 93: E541. DOI: 10.1016/J.Ijrobp.2015.07.1933  0.01
2015 Ryan Smith M, Vayalil PK, Zhou F, Benavides GA, Beggs R, Golzarian H, Nijampatnam B, Oliver PG, Smith RAJ, Murphy MP, Velu SE, Landar A. Mitochondrial Protein Thiols Control Metabolism by Modulating Activity and Levels of Key Metabolic Enzymes Free Radical Biology and Medicine. 87: S152. DOI: 10.1016/J.Freeradbiomed.2015.10.394  0.01
2015 Murphy M. Regulation of Mitochondrial reactive Oxygen species by Succinate Free Radical Biology and Medicine. 87: S7. DOI: 10.1016/J.Freeradbiomed.2015.10.011  0.01
2015 Helman AM, Murphy MP. Vascular cognitive impairment: Modeling a critical neurologic disease in vitro and in vivo Biochimica Et Biophysica Acta - Molecular Basis of Disease. DOI: 10.1016/j.bbadis.2015.12.009  1
2015 Haarmann J, Murphy MP, Peters CS, Staecker PC. Homotopy Equivalence in Finite Digital Images Journal of Mathematical Imaging and Vision. 53: 288-302. DOI: 10.1007/s10851-015-0578-8  1
2014 Stoyanovsky DA, Jiang J, Murphy MP, Epperly M, Zhang X, Li S, Greenberger J, Kagan V, Bay?r H. Design and Synthesis of a Mitochondria-Targeted Mimic of Glutathione Peroxidase, MitoEbselen-2, as a Radiation Mitigator. Acs Medicinal Chemistry Letters. 5: 1304-1307. PMID 25530831 DOI: 10.1021/Ml5003635  1
2014 Chouchani ET, Pell VR, Gaude E, Aksentijević D, Sundier SY, Robb EL, Logan A, Nadtochiy SM, Ord EN, Smith AC, Eyassu F, Shirley R, Hu CH, Dare AJ, James AM, ... ... Murphy MP, et al. Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Nature. 515: 431-5. PMID 25383517 DOI: 10.1038/Nature13909  1
2014 Schwarzländer M, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ, Fricker MD, Gems D, Halestrap AP, Halliwell B, Jakob U, ... ... Murphy MP, et al. The 'mitoflash' probe cpYFP does not respond to superoxide. Nature. 514: E12-4. PMID 25341790 DOI: 10.1038/Nature13858  1
2014 Prasain N, Lee MR, Vemula S, Meador JL, Yoshimoto M, Ferkowicz MJ, Fett A, Gupta M, Rapp BM, Saadatzadeh MR, Ginsberg M, Elemento O, Lee Y, Voytik-Harbin SL, Chung HM, ... ... Murphy MP, et al. Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells. Nature Biotechnology. 32: 1151-7. PMID 25306246 DOI: 10.1038/Nbt.3048  1
2014 McManus MJ, Murphy MP, Franklin JL. Mitochondria-derived reactive oxygen species mediate caspase-dependent and -independent neuronal deaths. Molecular and Cellular Neurosciences. 63: 13-23. PMID 25239010 DOI: 10.1016/j.mcn.2014.09.002  1
2014 Dunn EA, Roxburgh M, Larsen L, Smith RA, McLellan AD, Heikal A, Murphy MP, Cook GM. Incorporation of triphenylphosphonium functionality improves the inhibitory properties of phenothiazine derivatives in Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry. 22: 5320-8. PMID 25150092 DOI: 10.1016/j.bmc.2014.07.050  1
2014 Saez-Atienzar S, Bonet-Ponce L, Blesa JR, Romero FJ, Murphy MP, Jordan J, Galindo MF. The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells: involvement of Drp-1-mediated mitochondrial fission and mitochondrial-derived ROS signaling. Cell Death & Disease. 5: e1368. PMID 25118928 DOI: 10.1038/cddis.2014.320  1
2014 Feillet-Coudray C, Fouret G, Ebabe Elle R, Rieusset J, Bonafos B, Chabi B, Crouzier D, Zarkovic K, Zarkovic N, Ramos J, Badia E, Murphy MP, Cristol JP, Coudray C. The mitochondrial-targeted antioxidant MitoQ ameliorates metabolic syndrome features in obesogenic diet-fed rats better than Apocynin or Allopurinol. Free Radical Research. 48: 1232-46. PMID 25066801 DOI: 10.3109/10715762.2014.945079  1
2014 Wang A, Keita Ã…V, Phan V, McKay CM, Schoultz I, Lee J, Murphy MP, Fernando M, Ronaghan N, Balce D, Yates R, Dicay M, Beck PL, MacNaughton WK, Söderholm JD, et al. Targeting mitochondria-derived reactive oxygen species to reduce epithelial barrier dysfunction and colitis. The American Journal of Pathology. 184: 2516-27. PMID 25034594 DOI: 10.1016/J.Ajpath.2014.05.019  1
2014 Holler CJ, Davis PR, Beckett TL, Platt TL, Webb RL, Head E, Murphy MP. Bridging integrator 1 (BIN1) protein expression increases in the Alzheimer's disease brain and correlates with neurofibrillary tangle pathology. Journal of Alzheimer's Disease : Jad. 42: 1221-7. PMID 25024306 DOI: 10.3233/Jad-132450  1
2014 Martin SB, Dowling AL, Lianekhammy J, Lott IT, Doran E, Murphy MP, Beckett TL, Schmitt FA, Head E. Synaptophysin and synaptojanin-1 in Down syndrome are differentially affected by Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 42: 767-75. PMID 24927707 DOI: 10.3233/Jad-140795  1
2014 Niedowicz DM, Reeves VL, Platt TL, Kohler K, Beckett TL, Powell DK, Lee TL, Sexton TR, Song ES, Brewer LD, Latimer CS, Kraner SD, Larson KL, Ozcan S, Norris CM, ... ... Murphy MP, et al. Obesity and diabetes cause cognitive dysfunction in the absence of accelerated β-amyloid deposition in a novel murine model of mixed or vascular dementia. Acta Neuropathologica Communications. 2: 64. PMID 24916066 DOI: 10.1186/2051-5960-2-64  1
2014 Methner C, Chouchani ET, Buonincontri G, Pell VR, Sawiak SJ, Murphy MP, Krieg T. Mitochondria selective S-nitrosation by mitochondria-targeted S-nitrosothiol protects against post-infarct heart failure in mouse hearts. European Journal of Heart Failure. 16: 712-7. PMID 24891297 DOI: 10.1002/ejhf.100  1
2014 Swartwout K, Murphy MP, Dreher MC, Behal R, Haines A, Ryan M, Ryan N, Saba M. Advanced practice nursing students in the patient-centered medical home: preparing for a new reality. Journal of Professional Nursing : Official Journal of the American Association of Colleges of Nursing. 30: 139-48. PMID 24720942 DOI: 10.1016/J.Profnurs.2013.07.004  1
2014 Chouchani ET, Methner C, Buonincontri G, Hu CH, Logan A, Sawiak SJ, Murphy MP, Krieg T. Complex I deficiency due to selective loss of Ndufs4 in the mouse heart results in severe hypertrophic cardiomyopathy. Plos One. 9: e94157. PMID 24705922 DOI: 10.1371/journal.pone.0094157  1
2014 Binagwaho A, Farmer PE, Nsanzimana S, Karema C, Gasana M, de Dieu Ngirabega J, Ngabo F, Wagner CM, Nutt CT, Nyatanyi T, Gatera M, Kayiteshonga Y, Mugeni C, Mugwaneza P, Shema J, ... ... Murphy MP, et al. Rwanda 20 years on: investing in life. Lancet. 384: 371-5. PMID 24703831 DOI: 10.1016/S0140-6736(14)60574-2  1
2014 Cairns AG, Senn HM, Murphy MP, Hartley RC. Expanding the palette of phenanthridinium cations. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 3742-51. PMID 24677631 DOI: 10.1002/chem.201304241  1
2014 Gioscia-Ryan RA, LaRocca TJ, Sindler AL, Zigler MC, Murphy MP, Seals DR. Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice. The Journal of Physiology. 592: 2549-61. PMID 24665093 DOI: 10.1113/Jphysiol.2013.268680  1
2014 Yu E, Calvert PA, Mercer JR, Harrison J, Baker L, Figg NL, Kumar S, Wang JJ, Hurst LA, Obaid DR, Logan A, West NE, Clarke MC, Vidal-Puig A, Murphy MP, et al. Response to letter regarding article, "Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans". Circulation. 129: e408. PMID 24664223 DOI: 10.1161/CIRCULATIONAHA.113.008032  1
2014 Logan A, Shabalina IG, Prime TA, Rogatti S, Kalinovich AV, Hartley RC, Budd RC, Cannon B, Murphy MP. In vivo levels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice. Aging Cell. 13: 765-8. PMID 24621297 DOI: 10.1111/Acel.12212  1
2014 Miquel E, Cassina A, Martínez-Palma L, Souza JM, Bolatto C, Rodríguez-Bottero S, Logan A, Smith RA, Murphy MP, Barbeito L, Radi R, Cassina P. Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis. Free Radical Biology & Medicine. 70: 204-13. PMID 24582549 DOI: 10.1016/j.freeradbiomed.2014.02.019  1
2014 Carpenter KL, Jalloh I, Gallagher CN, Grice P, Howe DJ, Mason A, Timofeev I, Helmy A, Murphy MP, Menon DK, Kirkpatrick PJ, Carpenter TA, Sutherland GR, Pickard JD, Hutchinson PJ. (13)C-labelled microdialysis studies of cerebral metabolism in TBI patients. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 57: 87-97. PMID 24361470 DOI: 10.1016/J.Ejps.2013.12.012  1
2014 van der Burgh R, Nijhuis L, Pervolaraki K, Compeer EB, Jongeneel LH, van Gijn M, Coffer PJ, Murphy MP, Mastroberardino PG, Frenkel J, Boes M. Defects in mitochondrial clearance predispose human monocytes to interleukin-1β hypersecretion. The Journal of Biological Chemistry. 289: 5000-12. PMID 24356959 DOI: 10.1074/Jbc.M113.536920  1
2014 Farr SA, Ripley JL, Sultana R, Zhang Z, Niehoff ML, Platt TL, Murphy MP, Morley JE, Kumar V, Butterfield DA. Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease. Free Radical Biology & Medicine. 67: 387-95. PMID 24355211 DOI: 10.1016/J.Freeradbiomed.2013.11.014  1
2014 Pun PB, Logan A, Darley-Usmar V, Chacko B, Johnson MS, Huang GW, Rogatti S, Prime TA, Methner C, Krieg T, Fearnley IM, Larsen L, Larsen DS, Menger KE, Collins Y, ... ... Murphy MP, et al. A mitochondria-targeted mass spectrometry probe to detect glyoxals: implications for diabetes. Free Radical Biology & Medicine. 67: 437-50. PMID 24316194 DOI: 10.1016/J.Freeradbiomed.2013.11.025  1
2014 McLachlan J, Beattie E, Murphy MP, Koh-Tan CH, Olson E, Beattie W, Dominiczak AF, Nicklin SA, Graham D. Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function. Journal of Hypertension. 32: 555-64. PMID 24309493 DOI: 10.1097/HJH.0000000000000054  1
2014 Rogers C, Davis B, Neufer PD, Murphy MP, Anderson EJ, Robidoux J. A transient increase in lipid peroxidation primes preadipocytes for delayed mitochondrial inner membrane permeabilization and ATP depletion during prolonged exposure to fatty acids. Free Radical Biology & Medicine. 67: 330-41. PMID 24269897 DOI: 10.1016/J.Freeradbiomed.2013.11.012  1
2014 Zhao Y, Gillen JR, Harris DA, Kron IL, Murphy MP, Lau CL. Treatment with placenta-derived mesenchymal stem cells mitigates development of bronchiolitis obliterans in a murine model. The Journal of Thoracic and Cardiovascular Surgery. 147: 1668-1677.e5. PMID 24199758 DOI: 10.1016/j.jtcvs.2013.09.041  1
2014 Murphy MP, Miller JM, Siomos MZ, Braun L, Hinch B, Swartwout K. Integrating gerontological content across advanced practice registered nurse programs. Journal of the American Association of Nurse Practitioners. 26: 77-84. PMID 24170309 DOI: 10.1002/2327-6924.12074  1
2014 Bradley-Whitman MA, Timmons MD, Beckett TL, Murphy MP, Lynn BC, Lovell MA. Nucleic acid oxidation: an early feature of Alzheimer's disease. Journal of Neurochemistry. 128: 294-304. PMID 24032632 DOI: 10.1111/Jnc.12444  1
2014 Logan A, Cochemé HM, Li Pun PB, Apostolova N, Smith RA, Larsen L, Larsen DS, James AM, Fearnley IM, Rogatti S, Prime TA, Finichiu PG, Dare A, Chouchani ET, Pell VR, ... ... Murphy MP, et al. Using exomarkers to assess mitochondrial reactive species in vivo. Biochimica Et Biophysica Acta. 1840: 923-30. PMID 23726990 DOI: 10.1016/j.bbagen.2013.05.026  1
2014 Murphy MP, Carmine H, Kolakowsky-Hayner S. Modifiable and nonmodifiable risk factors for falls after traumatic brain injury: an exploratory investigation with implications for medication use. Rehabilitation Nursing : the Official Journal of the Association of Rehabilitation Nurses. 39: 113-22. PMID 23720011 DOI: 10.1002/rnj.89  1
2014 Murphy MP. Antioxidants as therapies: can we improve on nature? Free Radical Biology & Medicine. 66: 20-3. PMID 23603661 DOI: 10.1016/j.freeradbiomed.2013.04.010  1
2014 Mallon D, Brais R, Dare A, Murphy M, Bradley J, Pettigrew G, Saeb-Parsy K. Are We Discarding Transplantable Pancreases? Correlation Between Donor Demographics, Surgical Assessment and Histopathology. Transplantation. 98: 852. DOI: 10.1097/00007890-201407151-02907  0.01
2014 Chouchani E, Pell V, Gaude E, Aksentijevic D, Shattock M, Davidson S, Duchen M, Frezza C, Krieg T, Murphy M. P439Comparative metabolomics identifies conserved metabolic pathways that control mitochondrial ROS production during ischaemia reperfusion injury Cardiovascular Research. 103: S81.1-S81. DOI: 10.1093/Cvr/Cvu091.118  0.01
2014 Murphy MP. Ireland: Celtic Tiger in Austerity-Explaining Irish Path Dependency Journal of Contemporary European Studies. 22: 132-142. DOI: 10.1080/14782804.2014.902367  1
2014 Bardakjian HH, McReynolds MR, Murphy MP. Additional design considerations for special applications of steel pipe Pipelines 2014: From Underground to the Forefront of Innovation and Sustainability - Proceedings of the Pipelines 2014 Conference. 650-661. DOI: 10.1061/9780784413692.060  1
2014 Mueller RI, Murphy MP, Hall SC. Discussion of "pipe efficiency analysis at a water utility" by Amarjit Singh and Stacy Adachi Journal of Pipeline Systems Engineering and Practice. 5. DOI: 10.1061/(ASCE)PS.1949-1204.0000097  1
2014 Yu E, Calvert P, Mercer J, Harrison J, Baker L, Figg N, Kumar S, Wang J, Hurst L, Obaid D, Logan A, West N, Clarke M, Vidal-Puig A, Murphy M, et al. Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species and correlates with higher risk plaques in humans Atherosclerosis. 232: e3. DOI: 10.1016/j.atherosclerosis.2013.11.005  0.01
2013 Li L, Brichard L, Larsen L, Menon DK, Smith RA, Murphy MP, Aigbirhio FI. Radiosynthesis of 11-[(18) F]fluoroundecyltriphenylphosphonium (MitoF) as a potential mitochondria-specific positron emission tomography radiotracer. Journal of Labelled Compounds & Radiopharmaceuticals. 56: 717-21. PMID 24339010 DOI: 10.1002/Jlcr.3109  1
2013 Pearce LR, Atanassova N, Banton MC, Bottomley B, van der Klaauw AA, Revelli JP, Hendricks A, Keogh JM, Henning E, Doree D, Jeter-Jones S, Garg S, Bochukova EG, Bounds R, Ashford S, ... ... Murphy MP, et al. KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation. Cell. 155: 765-77. PMID 24209692 DOI: 10.1016/J.Cell.2013.09.058  1
2013 Davies AL, Desai RA, Bloomfield PS, McIntosh PR, Chapple KJ, Linington C, Fairless R, Diem R, Kasti M, Murphy MP, Smith KJ. Neurological deficits caused by tissue hypoxia in neuroinflammatory disease. Annals of Neurology. 74: 815-25. PMID 24038279 DOI: 10.1002/Ana.24006  1
2013 Hardas SS, Sultana R, Clark AM, Beckett TL, Szweda LI, Murphy MP, Butterfield DA. Oxidative modification of lipoic acid by HNE in Alzheimer disease brain. Redox Biology. 1: 80-5. PMID 24024140 DOI: 10.1016/J.Redox.2013.01.002  0.56
2013 Murphy MP. Mitochondrial dysfunction indirectly elevates ROS production by the endoplasmic reticulum. Cell Metabolism. 18: 145-6. PMID 23931748 DOI: 10.1016/j.cmet.2013.07.006  1
2013 Dashdorj A, Jyothi KR, Lim S, Jo A, Nguyen MN, Ha J, Yoon KS, Kim HJ, Park JH, Murphy MP, Kim SS. Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines. Bmc Medicine. 11: 178. PMID 23915129 DOI: 10.1186/1741-7015-11-178  1
2013 Akingba AG, Robinson EA, Jester AL, Rapp BM, Tsai A, Motaganahalli RL, Dalsing MC, Murphy MP. Management of vascular trauma from dog bites. Journal of Vascular Surgery. 58: 1346-52. PMID 23891489 DOI: 10.1016/j.jvs.2013.05.101  1
2013 Yu E, Calvert PA, Mercer JR, Harrison J, Baker L, Figg NL, Kumar S, Wang JC, Hurst LA, Obaid DR, Logan A, West NE, Clarke MC, Vidal-Puig A, Murphy MP, et al. Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans. Circulation. 128: 702-12. PMID 23841983 DOI: 10.1161/CIRCULATIONAHA.113.002271  1
2013 Murphy MP. Special issue: animal models of disease. Biochimica Et Biophysica Acta. 1832: 1361. PMID 23722202 DOI: 10.1016/j.bbadis.2013.05.024  1
2013 Chouchani ET, Methner C, Nadtochiy SM, Logan A, Pell VR, Ding S, James AM, Cochemé HM, Reinhold J, Lilley KS, Partridge L, Fearnley IM, Robinson AJ, Hartley RC, Smith RA, ... ... Murphy MP, et al. Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I. Nature Medicine. 19: 753-9. PMID 23708290 DOI: 10.1038/Nm.3212  1
2013 Reily C, Mitchell T, Chacko BK, Benavides G, Murphy MP, Darley-Usmar V. Mitochondrially targeted compounds and their impact on cellular bioenergetics. Redox Biology. 1: 86-93. PMID 23667828 DOI: 10.1016/J.Redox.2012.11.009  1
2013 Kling DE, Tsvang I, Murphy MP, Newburg DS. Group B Streptococcus induces a caspase-dependent apoptosis in fetal rat lung interstitium. Microbial Pathogenesis. 61: 1-10. PMID 23624260 DOI: 10.1016/j.micpath.2013.04.008  1
2013 Platt TL, Reeves VL, Murphy MP. Transgenic models of Alzheimer's disease: better utilization of existing models through viral transgenesis. Biochimica Et Biophysica Acta. 1832: 1437-48. PMID 23619198 DOI: 10.1016/J.Bbadis.2013.04.017  1
2013 Sikora A, Zielonka J, Adamus J, Debski D, Dybala-Defratyka A, Michalowski B, Joseph J, Hartley RC, Murphy MP, Kalyanaraman B. Reaction between peroxynitrite and triphenylphosphonium-substituted arylboronic acid isomers: identification of diagnostic marker products and biological implications. Chemical Research in Toxicology. 26: 856-67. PMID 23611338 DOI: 10.1021/Tx300499C  1
2013 Di Domenico F, Coccia R, Cocciolo A, Murphy MP, Cenini G, Head E, Butterfield DA, Giorgi A, Schinina ME, Mancuso C, Cini C, Perluigi M. Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain. Biochimica Et Biophysica Acta. 1832: 1249-59. PMID 23603808 DOI: 10.1016/J.Bbadis.2013.04.013  1
2013 Hare JM, Bolli R, Cooke JP, Gordon DJ, Henry TD, Perin EC, March KL, Murphy MP, Pepine CJ, Simari RD, Skarlatos SI, Traverse JH, Willerson JT, Szady AD, Taylor DA, et al. Phase II clinical research design in cardiology: learning the right lessons too well: observations and recommendations from the Cardiovascular Cell Therapy Research Network (CCTRN). Circulation. 127: 1630-5. PMID 23588961 DOI: 10.1161/Circulationaha.112.000779  1
2013 Mourtada R, Fonseca SB, Wisnovsky SP, Pereira MP, Wang X, Hurren R, Parfitt J, Larsen L, Smith RA, Murphy MP, Schimmer AD, Kelley SO. Re-directing an alkylating agent to mitochondria alters drug target and cell death mechanism. Plos One. 8: e60253. PMID 23585833 DOI: 10.1371/Journal.Pone.0060253  1
2013 Amtul Z, Park JW, Murphy MP, Siddiqui RA, Choudhary MI. Dietary lipids and Alzheimer's disease. Current Alzheimer Research. 10: 542-8. PMID 23566347 DOI: 10.2174/1567205011310050010  1
2013 Porteous CM, Menon DK, Aigbirhio FI, Smith RA, Murphy MP. P-glycoprotein (Mdr1a/1b) and breast cancer resistance protein (Bcrp) decrease the uptake of hydrophobic alkyl triphenylphosphonium cations by the brain. Biochimica Et Biophysica Acta. 1830: 3458-65. PMID 23454352 DOI: 10.1016/J.Bbagen.2013.02.005  1
2013 Murphy MP, Siegel RM. Mitochondrial ROS fire up T cell activation. Immunity. 38: 201-2. PMID 23438817 DOI: 10.1016/j.immuni.2013.02.005  1
2013 Methner C, Lukowski R, Grube K, Loga F, Smith RA, Murphy MP, Hofmann F, Krieg T. Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G. Basic Research in Cardiology. 108: 337. PMID 23423145 DOI: 10.1007/s00395-013-0337-1  1
2013 Beckett TL, Studzinski CM, Keller JN, Paul Murphy M, Niedowicz DM. A ketogenic diet improves motor performance but does not affect β-amyloid levels in a mouse model of Alzheimer's disease. Brain Research. 1505: 61-7. PMID 23415649 DOI: 10.1016/J.Brainres.2013.01.046  0.36
2013 Lowes DA, Webster NR, Murphy MP, Galley HF. Antioxidants that protect mitochondria reduce interleukin-6 and oxidative stress, improve mitochondrial function, and reduce biochemical markers of organ dysfunction in a rat model of acute sepsis. British Journal of Anaesthesia. 110: 472-80. PMID 23381720 DOI: 10.1093/bja/aes577  1
2013 Mugoni V, Postel R, Catanzaro V, De Luca E, Turco E, Digilio G, Silengo L, Murphy MP, Medana C, Stainier DY, Bakkers J, Santoro MM. Ubiad1 is an antioxidant enzyme that regulates eNOS activity by CoQ10 synthesis. Cell. 152: 504-18. PMID 23374346 DOI: 10.1016/j.cell.2013.01.013  1
2013 Harris JM, Esain V, Frechette GM, Harris LJ, Cox AG, Cortes M, Garnaas MK, Carroll KJ, Cutting CC, Khan T, Elks PM, Renshaw SA, Dickinson BC, Chang CJ, Murphy MP, et al. Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo. Blood. 121: 2483-93. PMID 23341543 DOI: 10.1182/Blood-2012-12-471201  1
2013 Zhang L, Dasuri K, Fernandez-Kim SO, Bruce-Keller AJ, Freeman LR, Pepping JK, Beckett TL, Murphy MP, Keller JN. Prolonged diet induced obesity has minimal effects towards brain pathology in mouse model of cerebral amyloid angiopathy: implications for studying obesity-brain interactions in mice. Biochimica Et Biophysica Acta. 1832: 1456-62. PMID 23313575 DOI: 10.1016/J.Bbadis.2013.01.002  1
2013 Niedowicz DM, Studzinski CM, Weidner AM, Platt TL, Kingry KN, Beckett TL, Bruce-Keller AJ, Keller JN, Murphy MP. Leptin regulates amyloid β production via the γ-secretase complex. Biochimica Et Biophysica Acta. 1832: 439-44. PMID 23274884 DOI: 10.1016/J.Bbadis.2012.12.009  1
2013 Finichiu PG, James AM, Larsen L, Smith RA, Murphy MP. Mitochondrial accumulation of a lipophilic cation conjugated to an ionisable group depends on membrane potential, pH gradient and pK(a): implications for the design of mitochondrial probes and therapies. Journal of Bioenergetics and Biomembranes. 45: 165-73. PMID 23180142 DOI: 10.1007/s10863-012-9493-5  1
2013 Pop V, Sorensen DW, Kamper JE, Ajao DO, Murphy MP, Head E, Hartman RE, Badaut J. Early brain injury alters the blood-brain barrier phenotype in parallel with β-amyloid and cognitive changes in adulthood. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 205-14. PMID 23149553 DOI: 10.1038/Jcbfm.2012.154  0.36
2013 Mackenzie RM, Salt IP, Miller WH, Logan A, Ibrahim HA, Degasperi A, Dymott JA, Hamilton CA, Murphy MP, Delles C, Dominiczak AF. Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes. Clinical Science (London, England : 1979). 124: 403-11. PMID 23057846 DOI: 10.1042/CS20120239  1
2013 Solesio ME, Prime TA, Logan A, Murphy MP, Del Mar Arroyo-Jimenez M, Jordán J, Galindo MF. The mitochondria-targeted anti-oxidant MitoQ reduces aspects of mitochondrial fission in the 6-OHDA cell model of Parkinson's disease. Biochimica Et Biophysica Acta. 1832: 174-82. PMID 22846607 DOI: 10.1016/j.bbadis.2012.07.009  1
2013 Holler CJ, Murphy MP. BACE1: Expression, regulation, and therapeutic potential of the major Alzheimer's disease beta-Secretase Current Enzyme Inhibition. 9: 3-14. DOI: 10.2174/1573408011309010003  1
2013 Abe Y, Stephens B, Murphy MP, Rizzi AA. Dynamic whole-body robotic manipulation Proceedings of Spie - the International Society For Optical Engineering. 8741. DOI: 10.1117/12.2016000  1
2013 Cunniff B, Nelson KJ, Newick K, Todd Lowther W, Chouchani ET, James AM, Murphy MP, Heintz NH. The Anti-Cancer Agent Thiostrepton Inactivates Peroxiredoxin 3 through Adduction of Specific Cysteine Residues Free Radical Biology and Medicine. 65: S17. DOI: 10.1016/J.Freeradbiomed.2013.10.420  0.01
2013 Foster J, Kealy J, Cherubini T, Businger S, Lu Z, Murphy M. The utility of atmospheric analyses for the mitigation of artifacts in InSAR Journal of Geophysical Research: Solid Earth. 118: 748-758. DOI: 10.1002/Jgrb.50093  1
2012 Rapp BM, Saadatzedeh MR, Ofstein RH, Bhavsar JR, Tempel ZS, Moreno O, Morone P, Booth DA, Traktuev DO, Dalsing MC, Ingram DA, Yoder MC, March KL, Murphy MP. Resident Endothelial Progenitor Cells From Human Placenta Have Greater Vasculogenic Potential Than Circulating Endothelial Progenitor Cells From Umbilical Cord Blood. Cell Medicine. 2: 85-96. PMID 27004134 DOI: 10.3727/215517911X617888  1
2012 Pelletier M, Lepow TS, Billingham LK, Murphy MP, Siegel RM. New tricks from an old dog: mitochondrial redox signaling in cellular inflammation. Seminars in Immunology. 24: 384-92. PMID 23391428 DOI: 10.1016/j.smim.2013.01.002  1
2012 Mizer JC, Ichim TE, Alexandrescu DT, Dasanu CA, Ramos F, Turner A, Woods EJ, Bogin V, Murphy MP, Koos D, Patel AN. Exogenous endothelial cells as accelerators of hematopoietic reconstitution. Journal of Translational Medicine. 10: 231. PMID 23171397 DOI: 10.1186/1479-5876-10-231  1
2012 Furman JL, Sama DM, Gant JC, Beckett TL, Murphy MP, Bachstetter AD, Van Eldik LJ, Norris CM. Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16129-40. PMID 23152597 DOI: 10.1523/Jneurosci.2323-12.2012  1
2012 Niedowicz DM, Beckett TL, Matveev S, Weidner AM, Baig I, Kryscio RJ, Mendiondo MS, LeVine H, Keller JN, Murphy MP. Pittsburgh compound B and the postmortem diagnosis of Alzheimer disease. Annals of Neurology. 72: 564-70. PMID 23109151 DOI: 10.1002/Ana.23633  1
2012 Kelso GF, Maroz A, Cochemé HM, Logan A, Prime TA, Peskin AV, Winterbourn CC, James AM, Ross MF, Brooker S, Porteous CM, Anderson RF, Murphy MP, Smith RA. A mitochondria-targeted macrocyclic Mn(II) superoxide dismutase mimetic. Chemistry & Biology. 19: 1237-46. PMID 23102218 DOI: 10.1016/j.chembiol.2012.08.005  1
2012 Murphy MP. Modulating mitochondrial intracellular location as a redox signal. Science Signaling. 5: pe39. PMID 22990116 DOI: 10.1126/scisignal.2003386  1
2012 Sharma AK, Lu G, Jester A, Johnston WF, Zhao Y, Hajzus VA, Saadatzadeh MR, Su G, Bhamidipati CM, Mehta GS, Kron IL, Laubach VE, Murphy MP, Ailawadi G, Upchurch GR. Experimental abdominal aortic aneurysm formation is mediated by IL-17 and attenuated by mesenchymal stem cell treatment. Circulation. 126: S38-45. PMID 22965992 DOI: 10.1161/Circulationaha.111.083451  1
2012 Jayaraman A, Carroll JC, Morgan TE, Lin S, Zhao L, Arimoto JM, Murphy MP, Beckett TL, Finch CE, Brinton RD, Pike CJ. 17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain. Endocrinology. 153: 5467-79. PMID 22962256 DOI: 10.1210/En.2012-1464  1
2012 Gala SG, Goodman JR, Murphy MP, Balsam MJ. Use of animals by NATO countries in military medical training exercises: an international survey. Military Medicine. 177: 907-10. PMID 22934368  0.01
2012 Schwarzländer M, Murphy MP, Duchen MR, Logan DC, Fricker MD, Halestrap AP, Müller FL, Rizzuto R, Dick TP, Meyer AJ, Sweetlove LJ. Mitochondrial 'flashes': a radical concept repHined. Trends in Cell Biology. 22: 503-8. PMID 22917552 DOI: 10.1016/J.Tcb.2012.07.007  1
2012 Hurd TR, Collins Y, Abakumova I, Chouchani ET, Baranowski B, Fearnley IM, Prime TA, Murphy MP, James AM. Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species. The Journal of Biological Chemistry. 287: 35153-60. PMID 22910903 DOI: 10.1074/jbc.M112.400002  1
2012 Head E, Murphey HL, Dowling AL, McCarty KL, Bethel SR, Nitz JA, Pleiss M, Vanrooyen J, Grossheim M, Smiley JR, Murphy MP, Beckett TL, Pagani D, Bresch F, Hendrix C. A combination cocktail improves spatial attention in a canine model of human aging and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 32: 1029-42. PMID 22886019 DOI: 10.3233/JAD-2012-120937  1
2012 James AM, Collins Y, Logan A, Murphy MP. Mitochondrial oxidative stress and the metabolic syndrome. Trends in Endocrinology and Metabolism: Tem. 23: 429-34. PMID 22831852 DOI: 10.1016/j.tem.2012.06.008  1
2012 Motaganahalli R, Martin A, Feliciano B, Murphy MP, Slaven J, Dalsing MC. Estimating the risk of solid organ malignancy in patients undergoing routine computed tomography scans after endovascular aneurysm repair. Journal of Vascular Surgery. 56: 929-37. PMID 22784414 DOI: 10.1016/j.jvs.2012.02.061  1
2012 Pun PB, Murphy MP. Pathological significance of mitochondrial glycation. International Journal of Cell Biology. 2012: 843505. PMID 22778743 DOI: 10.1155/2012/843505  1
2012 Beckett TL, Webb RL, Niedowicz DM, Holler CJ, Matveev S, Baig I, LeVine H, Keller JN, Murphy MP. Postmortem Pittsburgh Compound B (PiB) binding increases with Alzheimer's disease progression. Journal of Alzheimer's Disease : Jad. 32: 127-38. PMID 22766739 DOI: 10.3233/Jad-2012-120655  1
2012 von Montfort C, Matias N, Fernandez A, Fucho R, Conde de la Rosa L, Martinez-Chantar ML, Mato JM, Machida K, Tsukamoto H, Murphy MP, Mansouri A, Kaplowitz N, Garcia-Ruiz C, Fernandez-Checa JC. Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis. Journal of Hepatology. 57: 852-9. PMID 22687340 DOI: 10.1016/J.Jhep.2012.05.024  1
2012 Prime TA, Forkink M, Logan A, Finichiu PG, McLachlan J, Li Pun PB, Koopman WJ, Larsen L, Latter MJ, Smith RA, Murphy MP. A ratiometric fluorescent probe for assessing mitochondrial phospholipid peroxidation within living cells. Free Radical Biology & Medicine. 53: 544-53. PMID 22659314 DOI: 10.1016/j.freeradbiomed.2012.05.033  1
2012 Murphy MP. Progress report: why we still don't have a reliable gold standard for in vitro diagnostic genetic testing. Mlo: Medical Laboratory Observer. 44: 36, 38. PMID 22649968  1
2012 Duncan MJ, Smith JT, Franklin KM, Beckett TL, Murphy MP, St Clair DK, Donohue KD, Striz M, O'Hara BF. Effects of aging and genotype on circadian rhythms, sleep, and clock gene expression in APPxPS1 knock-in mice, a model for Alzheimer's disease. Experimental Neurology. 236: 249-58. PMID 22634208 DOI: 10.1016/J.Expneurol.2012.05.011  1
2012 Tarallo V, Hirano Y, Gelfand BD, Dridi S, Kerur N, Kim Y, Cho WG, Kaneko H, Fowler BJ, Bogdanovich S, Albuquerque RJ, Hauswirth WW, Chiodo VA, Kugel JF, Goodrich JA, ... ... Murphy MP, et al. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell. 149: 847-59. PMID 22541070 DOI: 10.1016/J.Cell.2012.03.036  1
2012 Murphy MP, Carmine H. Long-term health implications of individuals with TBI: a rehabilitation perspective. Neurorehabilitation. 31: 85-94. PMID 22523016 DOI: 10.3233/NRE-2012-0777  1
2012 Smith RA, Hartley RC, Cochemé HM, Murphy MP. Mitochondrial pharmacology. Trends in Pharmacological Sciences. 33: 341-52. PMID 22521106 DOI: 10.1016/j.tips.2012.03.010  1
2012 Cochemé HM, Logan A, Prime TA, Abakumova I, Quin C, McQuaker SJ, Patel JV, Fearnley IM, James AM, Porteous CM, Smith RA, Hartley RC, Partridge L, Murphy MP. Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila. Nature Protocols. 7: 946-58. PMID 22517261 DOI: 10.1038/nprot.2012.035  1
2012 Searcy JL, Phelps JT, Pancani T, Kadish I, Popovic J, Anderson KL, Beckett TL, Murphy MP, Chen KC, Blalock EM, Landfield PW, Porter NM, Thibault O. Long-term pioglitazone treatment improves learning and attenuates pathological markers in a mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 30: 943-61. PMID 22495349 DOI: 10.3233/Jad-2012-111661  1
2012 Webb RL, Murphy MP. β-Secretases, Alzheimer's Disease, and Down Syndrome. Current Gerontology and Geriatrics Research. 2012: 362839. PMID 22481915 DOI: 10.1155/2012/362839  1
2012 Collins Y, Chouchani ET, James AM, Menger KE, Cochemé HM, Murphy MP. Mitochondrial redox signalling at a glance. Journal of Cell Science. 125: 801-6. PMID 22448036 DOI: 10.1242/jcs.098475  1
2012 Rodriguez JP, Murphy MP, Hong S, Madrigal M, March KL, Minev B, Harman RJ, Chen CS, Timmons RB, Marleau AM, Riordan NH. Autologous stromal vascular fraction therapy for rheumatoid arthritis: rationale and clinical safety. International Archives of Medicine. 5: 5. PMID 22313603 DOI: 10.1186/1755-7682-5-5  1
2012 Teixeira J, Soares P, Benfeito S, Gaspar A, Garrido J, Murphy MP, Borges F. Rational discovery and development of a mitochondria-targeted antioxidant based on cinnamic acid scaffold. Free Radical Research. 46: 600-11. PMID 22292941 DOI: 10.3109/10715762.2012.662593  1
2012 Chalmers S, Caldwell ST, Quin C, Prime TA, James AM, Cairns AG, Murphy MP, McCarron JG, Hartley RC. Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore. Journal of the American Chemical Society. 134: 758-61. PMID 22239373 DOI: 10.1021/Ja2077922  1
2012 Mercer JR, Yu E, Figg N, Cheng KK, Prime TA, Griffin JL, Masoodi M, Vidal-Puig A, Murphy MP, Bennett MR. The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice. Free Radical Biology & Medicine. 52: 841-9. PMID 22210379 DOI: 10.1016/j.freeradbiomed.2011.11.026  1
2012 Eicher V, Murphy MP, Murphy TF, Malec JF. Progress assessed with the Mayo-Portland Adaptability Inventory in 604 participants in 4 types of post-inpatient rehabilitation brain injury programs. Archives of Physical Medicine and Rehabilitation. 93: 100-7. PMID 22200388 DOI: 10.1016/j.apmr.2011.06.038  1
2012 Davidson SM, Yellon DM, Murphy MP, Duchen MR. Slow calcium waves and redox changes precede mitochondrial permeability transition pore opening in the intact heart during hypoxia and reoxygenation. Cardiovascular Research. 93: 445-53. PMID 22198507 DOI: 10.1093/cvr/cvr349  1
2012 Pung YF, Rocic P, Murphy MP, Smith RA, Hafemeister J, Ohanyan V, Guarini G, Yin L, Chilian WM. Resolution of mitochondrial oxidative stress rescues coronary collateral growth in Zucker obese fatty rats. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 325-34. PMID 22155454 DOI: 10.1161/Atvbaha.111.241802  1
2012 Matos JM, Fajardo A, Dalsing MC, Motaganahalli R, Akingba GA, Murphy MP. Evidence for nonoperative management of acute limb ischemia in infants. Journal of Vascular Surgery. 55: 1156-9; discussion 1. PMID 22133454 DOI: 10.1016/j.jvs.2011.09.092  1
2012 Holler CJ, Webb RL, Laux AL, Beckett TL, Niedowicz DM, Ahmed RR, Liu Y, Simmons CR, Dowling AL, Spinelli A, Khurgel M, Estus S, Head E, Hersh LB, Murphy MP. BACE2 expression increases in human neurodegenerative disease. The American Journal of Pathology. 180: 337-50. PMID 22074738 DOI: 10.1016/J.Ajpath.2011.09.034  1
2012 Cenini G, Dowling AL, Beckett TL, Barone E, Mancuso C, Murphy MP, Levine H, Lott IT, Schmitt FA, Butterfield DA, Head E. Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome. Biochimica Et Biophysica Acta. 1822: 130-8. PMID 22009041 DOI: 10.1016/J.Bbadis.2011.10.001  1
2012 Barone E, Mancuso C, Di Domenico F, Sultana R, Murphy MP, Head E, Butterfield DA. Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease. Journal of Neurochemistry. 120: 135-46. PMID 22004509 DOI: 10.1111/J.1471-4159.2011.07538.X  1
2012 Murphy MP. Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles for glutathionylation and other thiol modifications. Antioxidants & Redox Signaling. 16: 476-95. PMID 21954972 DOI: 10.1089/ars.2011.4289  1
2012 Butterfield DA, Barone E, Di Domenico F, Cenini G, Sultana R, Murphy MP, Mancuso C, Head E. Atorvastatin treatment in a dog preclinical model of Alzheimer's disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 981-7. PMID 21767440 DOI: 10.1017/S1461145711001118  1
2012 Pop V, Head E, Berchtold NC, Glabe CG, Studzinski CM, Weidner AM, Murphy MP, Cotman CW. Aβ aggregation profiles and shifts in APP processing favor amyloidogenesis in canines. Neurobiology of Aging. 33: 108-20. PMID 20434811 DOI: 10.1016/J.Neurobiolaging.2010.02.008  1
2012 Murphy MP, Stephens B, Abe Y, Rizzi AA. High degree-of-freedom dynamic manipulation Proceedings of Spie - the International Society For Optical Engineering. 8387. DOI: 10.1117/12.919939  1
2012 Casner SM, Murphy MP, Neville EC, Neville MR. Pilots as Weather Briefers: The Direct Use of Aviation Weather Products by General Aviation Pilots International Journal of Aviation Psychology. 22: 367-381. DOI: 10.1080/10508414.2012.718241  1
2012 Zarghamee MS, Roy C, Murphy MP. Finite element analysis of combined-load performance of pressurecast™ steel pipe Pipelines 2012: Innovations in Design, Construction, Operations, and Maintenance - Doing More With Less - Proceedings of the Pipelines 2012 Conference. 996-1014. DOI: 10.1061/9780784412480.093  1
2012 Motaganahalli RL, Martin A, Slaven J, Murphy MP, Dalsing MC. Reply Journal of Vascular Surgery. 56: 1829. DOI: 10.1016/j.jvs.2012.08.096  1
2012 Oh JY, Ricart KC, Zhou F, Wall SB, Kumar PV, Westbrook DG, Moore R, Murphy M, Ballinger SW, Barnes S, Landar A. Inhibition of Cellular Metabolism by a Mitochondrially-Targeted Electrophile via Modification of Krebs Cycle Proteins in Vascular Endothelial Cells Free Radical Biology and Medicine. 53: S171. DOI: 10.1016/J.Freeradbiomed.2012.10.471  0.01
2012 Cauwels⁎ A, Vandendriessche B, Rogge E, Murphy M, Brouckaert P. New insights in the contribution and origin of reactive oxygen species in inflammation-induced mitochondrial damage, cell death, cardiovascular failure and shock Free Radical Biology and Medicine. 53: S113-S114. DOI: 10.1016/J.Freeradbiomed.2012.08.238  0.01
2012 Mitchell T, Rotaru D, Saba H, Smith RA, Murphy MP, Mac-Millan-Crow LA. Correction to "The mitochondria-targeted antioxidant mitoquinone protects against cold storage injury of renal tubular cells and rat kidneys" (J Pharmacol Exp Ther (2011) 336, (682-692)) Journal of Pharmacology and Experimental Therapeutics. 342: 596.  1
2011 Lim S, Rashid MA, Jang M, Kim Y, Won H, Lee J, Woo JT, Kim YS, Murphy MP, Ali L, Ha J, Kim SS. Mitochondria-targeted antioxidants protect pancreatic β-cells against oxidative stress and improve insulin secretion in glucotoxicity and glucolipotoxicity. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 28: 873-86. PMID 22178940 DOI: 10.1159/000335802  1
2011 McManus MJ, Murphy MP, Franklin JL. The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15703-15. PMID 22049413 DOI: 10.1523/JNEUROSCI.0552-11.2011  1
2011 Weidner AM, Bradley MA, Beckett TL, Niedowicz DM, Dowling AL, Matveev SV, LeVine H, Lovell MA, Murphy MP. RNA oxidation adducts 8-OHG and 8-OHA change with Aβ42 levels in late-stage Alzheimer's disease. Plos One. 6: e24930. PMID 21949792 DOI: 10.1371/Journal.Pone.0024930  1
2011 Bruce-Keller AJ, Gupta S, Knight AG, Beckett TL, McMullen JM, Davis PR, Murphy MP, Van Eldik LJ, St Clair D, Keller JN. Cognitive impairment in humanized APP×PS1 mice is linked to Aβ(1-42) and NOX activation. Neurobiology of Disease. 44: 317-26. PMID 21798347 DOI: 10.1016/J.Nbd.2011.07.012  1
2011 Martin SB, Cenini G, Barone E, Dowling AL, Mancuso C, Butterfield DA, Murphy MP, Head E. Coenzyme Q10 and cognition in atorvastatin treated dogs. Neuroscience Letters. 501: 92-5. PMID 21763754 DOI: 10.1016/J.Neulet.2011.06.054  1
2011 Lagoe RJ, Johnson PE, Murphy MP. Inpatient hospital complications and lengths of stay: a short report. Bmc Research Notes. 4: 135. PMID 21545741 DOI: 10.1186/1756-0500-4-135  1
2011 Chacko BK, Srivastava A, Johnson MS, Benavides GA, Chang MJ, Ye Y, Jhala N, Murphy MP, Kalyanaraman B, Darley-Usmar VM. Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis. Hepatology (Baltimore, Md.). 54: 153-63. PMID 21520201 DOI: 10.1002/Hep.24377  1
2011 Murphy MP, Lawson JH, Rapp BM, Dalsing MC, Klein J, Wilson MG, Hutchins GD, March KL. Autologous bone marrow mononuclear cell therapy is safe and promotes amputation-free survival in patients with critical limb ischemia. Journal of Vascular Surgery. 53: 1565-74.e1. PMID 21514773 DOI: 10.1016/J.Jvs.2011.01.074  1
2011 Weidner AM, Housley M, Murphy MP, Levine H. Purified high molecular weight synthetic Aβ(1-42) and biological Aβ oligomers are equipotent in rapidly inducing MTT formazan exocytosis. Neuroscience Letters. 497: 1-5. PMID 21504780 DOI: 10.1016/J.Neulet.2011.03.082  1
2011 Ma T, Hoeffer CA, Wong H, Massaad CA, Zhou P, Iadecola C, Murphy MP, Pautler RG, Klann E. Amyloid β-induced impairments in hippocampal synaptic plasticity are rescued by decreasing mitochondrial superoxide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 5589-95. PMID 21490199 DOI: 10.1523/Jneurosci.6566-10.2011  1
2011 Murphy MP, Holmgren A, Larsson NG, Halliwell B, Chang CJ, Kalyanaraman B, Rhee SG, Thornalley PJ, Partridge L, Gems D, Nyström T, Belousov V, Schumacker PT, Winterbourn CC. Unraveling the biological roles of reactive oxygen species. Cell Metabolism. 13: 361-6. PMID 21459321 DOI: 10.1016/J.Cmet.2011.03.010  1
2011 Lee S, Tak E, Lee J, Rashid MA, Murphy MP, Ha J, Kim SS. Mitochondrial H2O2 generated from electron transport chain complex I stimulates muscle differentiation. Cell Research. 21: 817-34. PMID 21445095 DOI: 10.1038/cr.2011.55  1
2011 Smith RA, Hartley RC, Murphy MP. Mitochondria-targeted small molecule therapeutics and probes. Antioxidants & Redox Signaling. 15: 3021-38. PMID 21395490 DOI: 10.1089/ars.2011.3969  1
2011 Cochemé HM, Quin C, McQuaker SJ, Cabreiro F, Logan A, Prime TA, Abakumova I, Patel JV, Fearnley IM, James AM, Porteous CM, Smith RA, Saeed S, Carré JE, Singer M, ... ... Murphy MP, et al. Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix. Cell Metabolism. 13: 340-50. PMID 21356523 DOI: 10.1016/j.cmet.2011.02.003  1
2011 Smith RA, Murphy MP. Mitochondria-targeted antioxidants as therapies. Discovery Medicine. 11: 106-14. PMID 21356165  1
2011 Barone E, Cenini G, Di Domenico F, Martin S, Sultana R, Mancuso C, Murphy MP, Head E, Butterfield DA. Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 63: 172-80. PMID 21193043 DOI: 10.1016/J.Phrs.2010.12.007  1
2011 Mitchell T, Rotaru D, Saba H, Smith RA, Murphy MP, MacMillan-Crow LA. The mitochondria-targeted antioxidant mitoquinone protects against cold storage injury of renal tubular cells and rat kidneys. The Journal of Pharmacology and Experimental Therapeutics. 336: 682-92. PMID 21159749 DOI: 10.1124/Jpet.110.176743  1
2011 Chouchani ET, James AM, Fearnley IM, Lilley KS, Murphy MP. Proteomic approaches to the characterization of protein thiol modification. Current Opinion in Chemical Biology. 15: 120-8. PMID 21130020 DOI: 10.1016/j.cbpa.2010.11.003  1
2011 Vlachantoni D, Bramall AN, Murphy MP, Taylor RW, Shu X, Tulloch B, Van Veen T, Turnbull DM, McInnes RR, Wright AF. Evidence of severe mitochondrial oxidative stress and a protective effect of low oxygen in mouse models of inherited photoreceptor degeneration. Human Molecular Genetics. 20: 322-35. PMID 21051333 DOI: 10.1093/Hmg/Ddq467  1
2011 Marthandan S, Murphy MP, Billett E, Barnett Y. An investigation of the effects of MitoQ on human peripheral mononuclear cells. Free Radical Research. 45: 351-8. PMID 21047171 DOI: 10.3109/10715762.2010.532497  1
2011 Methner C, Lukowski R, Hofmann F, Murphy M, Krieg T. Characterization of mice with a deletion of protein kinase G type I in cardiomyocytes and the effect on cardioprotection through either postconditioning or mitochondria-targeted S-nitrosothiol Bmc Pharmacology. 11. DOI: 10.1186/1471-2210-11-S1-O15  0.01
2011 Sikora AB, Zielonka J, Adamus J, Debski D, Joseph J, Murphy MP, Kalyanaraman B. Different Reaction Profiles of Mitochondria-Targeted Arylboronic Acid Isomers With Peroxynitrite Free Radical Biology and Medicine. 51: S149-S150. DOI: 10.1016/J.Freeradbiomed.2011.10.259  0.01
2011 Murphy MP, Head E. Impact of Aging on Brain Structure and Function in Rodents and Canines Fundamental Neuropathology For Pathologists and Toxicologists: Principles and Techniques. 125-138. DOI: 10.1002/9780470939956.ch8  1
2010 Ichim TE, Solano F, Lara F, Paris E, Ugalde F, Rodriguez JP, Minev B, Bogin V, Ramos F, Woods EJ, Murphy MP, Patel AN, Harman RJ, Riordan NH. Feasibility of combination allogeneic stem cell therapy for spinal cord injury: a case report. International Archives of Medicine. 3: 30. PMID 21070647 DOI: 10.1186/1755-7682-3-30  1
2010 Zhou A, Carrell RW, Murphy MP, Wei Z, Yan Y, Stanley PL, Stein PE, Broughton Pipkin F, Read RJ. A redox switch in angiotensinogen modulates angiotensin release. Nature. 468: 108-11. PMID 20927107 DOI: 10.1038/Nature09505  1
2010 Ebenezer PJ, Weidner AM, LeVine H, Markesbery WR, Murphy MP, Zhang L, Dasuri K, Fernandez-Kim SO, Bruce-Keller AJ, Gavilán E, Keller JN. Neuron specific toxicity of oligomeric amyloid-β: role for JUN-kinase and oxidative stress. Journal of Alzheimer's Disease : Jad. 22: 839-48. PMID 20858948 DOI: 10.3233/Jad-2010-101161  1
2010 Murphy MP, Morales J, Beckett TL, Astarita G, Piomelli D, Weidner A, Studzinski CM, Dowling AL, Wang X, Levine H, Kryscio RJ, Lin Y, Barrett E, Head E. Changes in cognition and amyloid-β processing with long term cholesterol reduction using atorvastatin in aged dogs. Journal of Alzheimer's Disease : Jad. 22: 135-50. PMID 20847439 DOI: 10.3233/Jad-2010-100639  1
2010 Requejo R, Chouchani ET, James AM, Prime TA, Lilley KS, Fearnley IM, Murphy MP. Quantification and identification of mitochondrial proteins containing vicinal dithiols. Archives of Biochemistry and Biophysics. 504: 228-35. PMID 20836988 DOI: 10.1016/j.abb.2010.09.003  1
2010 Chacko BK, Reily C, Srivastava A, Johnson MS, Ye Y, Ulasova E, Agarwal A, Zinn KR, Murphy MP, Kalyanaraman B, Darley-Usmar V. Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ. The Biochemical Journal. 432: 9-19. PMID 20825366 DOI: 10.1042/Bj20100308  1
2010 Estes ML, Mund JA, Mead LE, Prater DN, Cai S, Wang H, Pollok KE, Murphy MP, An CS, Srour EF, Ingram DA, Case J. Application of polychromatic flow cytometry to identify novel subsets of circulating cells with angiogenic potential. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 831-9. PMID 20803735 DOI: 10.1002/Cyto.A.20921  1
2010 Mercer JR, Cheng KK, Figg N, Gorenne I, Mahmoudi M, Griffin J, Vidal-Puig A, Logan A, Murphy MP, Bennett M. DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome. Circulation Research. 107: 1021-31. PMID 20705925 DOI: 10.1161/CIRCRESAHA.110.218966  1
2010 Pop V, Head E, Hill MA, Gillen D, Berchtold NC, Muggenburg BA, Milgram NW, Murphy MP, Cotman CW. Synergistic effects of long-term antioxidant diet and behavioral enrichment on beta-amyloid load and non-amyloidogenic processing in aged canines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9831-9. PMID 20660265 DOI: 10.1523/Jneurosci.6194-09.2010  1
2010 Ichim TE, Zhong Z, Mikirova NA, Jackson JA, Hunninghake R, Mansilla E, Marín G, Núñez L, Patel AN, Angle N, Murphy MP, Dasanu CA, Alexandrescu DT, Bogin V, Riordan NH. Circulating endothelial progenitor cells and erectile dysfunction: possibility of nutritional intervention? Panminerva Medica. 52: 75-80. PMID 20657539  1
2010 Smith RA, Murphy MP. Animal and human studies with the mitochondria-targeted antioxidant MitoQ. Annals of the New York Academy of Sciences. 1201: 96-103. PMID 20649545 DOI: 10.1111/j.1749-6632.2010.05627.x  1
2010 Porteous CM, Logan A, Evans C, Ledgerwood EC, Menon DK, Aigbirhio F, Smith RA, Murphy MP. Rapid uptake of lipophilic triphenylphosphonium cations by mitochondria in vivo following intravenous injection: implications for mitochondria-specific therapies and probes. Biochimica Et Biophysica Acta. 1800: 1009-17. PMID 20621583 DOI: 10.1016/J.Bbagen.2010.06.001  1
2010 Niedowicz DM, Beckett TL, Holler CJ, Weidner AM, Murphy MP. APP(DeltaNL695) expression in murine tissue downregulates CNBP expression. Neuroscience Letters. 482: 57-61. PMID 20621159 DOI: 10.1016/J.Neulet.2010.07.006  1
2010 Requejo R, Chouchani ET, Hurd TR, Menger KE, Hampton MB, Murphy MP. Measuring mitochondrial protein thiol redox state. Methods in Enzymology. 474: 123-47. PMID 20609908 DOI: 10.1016/S0076-6879(10)74008-8  1
2010 Snow BJ, Rolfe FL, Lockhart MM, Frampton CM, O'Sullivan JD, Fung V, Smith RA, Murphy MP, Taylor KM. A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 25: 1670-4. PMID 20568096 DOI: 10.1002/mds.23148  1
2010 Underwood BR, Imarisio S, Fleming A, Rose C, Krishna G, Heard P, Quick M, Korolchuk VI, Renna M, Sarkar S, García-Arencibia M, O'Kane CJ, Murphy MP, Rubinsztein DC. Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease. Human Molecular Genetics. 19: 3413-29. PMID 20566712 DOI: 10.1093/Hmg/Ddq253  1
2010 Liu Y, Studzinski C, Beckett T, Murphy MP, Klein RL, Hersh LB. Circulating neprilysin clears brain amyloid. Molecular and Cellular Neurosciences. 45: 101-7. PMID 20558294 DOI: 10.1016/J.Mcn.2010.05.014  1
2010 Chouchani ET, Hurd TR, Nadtochiy SM, Brookes PS, Fearnley IM, Lilley KS, Smith RA, Murphy MP. Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial function by reversible S-nitrosation. The Biochemical Journal. 430: 49-59. PMID 20533907 DOI: 10.1042/Bj20100633  1
2010 Beckett TL, Niedowicz DM, Studzinski CM, Weidner AM, Webb RL, Holler CJ, Ahmed RR, LeVine H, Murphy MP. Effects of nonsteroidal anti-inflammatory drugs on amyloid-beta pathology in mouse skeletal muscle. Neurobiology of Disease. 39: 449-56. PMID 20493261 DOI: 10.1016/J.Nbd.2010.05.018  1
2010 Gane EJ, Weilert F, Orr DW, Keogh GF, Gibson M, Lockhart MM, Frampton CM, Taylor KM, Smith RA, Murphy MP. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients. Liver International : Official Journal of the International Association For the Study of the Liver. 30: 1019-26. PMID 20492507 DOI: 10.1111/j.1478-3231.2010.02250.x  1
2010 Manczak M, Mao P, Calkins MJ, Cornea A, Reddy AP, Murphy MP, Szeto HH, Park B, Reddy PH. Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons. Journal of Alzheimer's Disease : Jad. 20: S609-31. PMID 20463406 DOI: 10.3233/JAD-2010-100564  1
2010 Bijangi-Vishehsaraei K, Saadatzadeh MR, Huang S, Murphy MP, Safa AR. 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide (CMH) targets mRNA of the c-FLIP variants and induces apoptosis in MCF-7 human breast cancer cells. Molecular and Cellular Biochemistry. 342: 133-42. PMID 20446019 DOI: 10.1007/s11010-010-0477-7  1
2010 Aluise CD, Robinson RA, Beckett TL, Murphy MP, Cai J, Pierce WM, Markesbery WR, Butterfield DA. Preclinical Alzheimer disease: brain oxidative stress, Abeta peptide and proteomics. Neurobiology of Disease. 39: 221-8. PMID 20399861 DOI: 10.1016/J.Nbd.2010.04.011  1
2010 Ichim TE, Solano F, Lara F, Rodriguez JP, Cristea O, Minev B, Ramos F, Woods EJ, Murphy MP, Alexandrescu DT, Patel AN, Riordan NH. Combination stem cell therapy for heart failure. International Archives of Medicine. 3: 5. PMID 20398245 DOI: 10.1186/1755-7682-3-5  1
2010 Mikirova NA, Jackson JA, Hunninghake R, Kenyon J, Chan KW, Swindlehurst CA, Minev B, Patel AN, Murphy MP, Smith L, Ramos F, Ichim TE, Riordan NH. Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects. Journal of Translational Medicine. 8: 34. PMID 20377846 DOI: 10.1186/1479-5876-8-34  1
2010 Murphy MP. Opportunities for grace. Medical Economics. 87: 47-8, 50. PMID 20377071  1
2010 James AM, Cochemé HM, Murai M, Miyoshi H, Murphy MP. Complementation of coenzyme Q-deficient yeast by coenzyme Q analogues requires the isoprenoid side chain. The Febs Journal. 277: 2067-82. PMID 20345901 DOI: 10.1111/j.1742-4658.2010.07622.x  1
2010 Cochemé HM, Murphy MP. Can antioxidants be effective therapeutics? Current Opinion in Investigational Drugs (London, England : 2000). 11: 426-31. PMID 20336590  1
2010 Webb RL, Findlay KA, Green MA, Beckett TL, Murphy MP. Efficient activation of reconstructed rat embryos by cyclin-dependent kinase inhibitors. Plos One. 5: e9799. PMID 20333307 DOI: 10.1371/journal.pone.0009799  1
2010 Head E, Pop V, Sarsoza F, Kayed R, Beckett TL, Studzinski CM, Tomic JL, Glabe CG, Murphy MP. Amyloid-beta peptide and oligomers in the brain and cerebrospinal fluid of aged canines. Journal of Alzheimer's Disease : Jad. 20: 637-46. PMID 20164551 DOI: 10.3233/Jad-2010-1397  1
2010 Requejo R, Hurd TR, Costa NJ, Murphy MP. Cysteine residues exposed on protein surfaces are the dominant intramitochondrial thiol and may protect against oxidative damage. The Febs Journal. 277: 1465-80. PMID 20148960 DOI: 10.1111/j.1742-4658.2010.07576.x  1
2010 Ziegler MA, Distasi MR, Bills RG, Miller SJ, Alloosh M, Murphy MP, Akingba AG, Sturek M, Dalsing MC, Unthank JL. Marvels, mysteries, and misconceptions of vascular compensation to peripheral artery occlusion. Microcirculation (New York, N.Y. : 1994). 17: 3-20. PMID 20141596 DOI: 10.1111/J.1549-8719.2010.00008.X  1
2010 Minczuk M, Kolasinska-Zwierz P, Murphy MP, Papworth MA. Construction and testing of engineered zinc-finger proteins for sequence-specific modification of mtDNA. Nature Protocols. 5: 342-56. PMID 20134433 DOI: 10.1038/Nprot.2009.245  1
2010 Bader Lange ML, St Clair D, Markesbery WR, Studzinski CM, Murphy MP, Butterfield DA. Age-related loss of phospholipid asymmetry in APP(NLh)/APP(NLh) x PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice: relevance to Alzheimer disease. Neurobiology of Disease. 38: 104-15. PMID 20083199 DOI: 10.1016/J.Nbd.2010.01.004  1
2010 Murphy MP, LeVine H. Alzheimer's disease and the amyloid-beta peptide. Journal of Alzheimer's Disease : Jad. 19: 311-23. PMID 20061647 DOI: 10.3233/JAD-2010-1221  1
2010 Ahmed RR, Holler CJ, Webb RL, Li F, Beckett TL, Murphy MP. BACE1 and BACE2 enzymatic activities in Alzheimer's disease. Journal of Neurochemistry. 112: 1045-53. PMID 19968762 DOI: 10.1111/J.1471-4159.2009.06528.X  1
2010 Ichim TE, Alexandrescu DT, Solano F, Lara F, Campion Rde N, Paris E, Woods EJ, Murphy MP, Dasanu CA, Patel AN, Marleau AM, Leal A, Riordan NH. Mesenchymal stem cells as anti-inflammatories: implications for treatment of Duchenne muscular dystrophy. Cellular Immunology. 260: 75-82. PMID 19917503 DOI: 10.1016/j.cellimm.2009.10.006  1
2010 Rodriguez-Cuenca S, Cochemé HM, Logan A, Abakumova I, Prime TA, Rose C, Vidal-Puig A, Smith AC, Rubinsztein DC, Fearnley IM, Jones BA, Pope S, Heales SJ, Lam BY, Neogi SG, ... ... Murphy MP, et al. Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice. Free Radical Biology & Medicine. 48: 161-72. PMID 19854266 DOI: 10.1016/j.freeradbiomed.2009.10.039  1
2010 Mackenzie RM, Hamilton CA, Miller WH, Salt IP, Murphy MP, Delles C, Dominiczak AF. 022 MitoQ10 decreases AMPK activation in endothelial cells from patients with coronary artery disease and diabetes Heart. 96: A15.1-A15. DOI: 10.1136/hrt.2010.195941.22  0.01
2010 McLachlan J, Hamilton CA, Beattie E, Murphy MP, Dominiczak AF, Nicklin SA, Graham D. 021 Therapeutic effects of MitoQ10 on hypertension and cardiac hypertrophy Heart. 96: A14.2-A15. DOI: 10.1136/hrt.2010.195941.21  0.01
2010 Salton JR, Buerger S, Marron L, Feddema J, Fischer G, Little C, Spletzer B, Xavier P, Rizzi AA, Murphy MP, Giarratana J, Malchano MD, Weagle CA. Urban Hopper Proceedings of Spie - the International Society For Optical Engineering. 7692. DOI: 10.1117/12.855599  1
2010 McLachlan J, Hamilton C, Beattie E, Murphy M, Dominiczak A, Nicklin S, Graham D. SYNERGISTIC EFFECTS OF A NOVEL MITOCHONDRIAL-ANTIOXIDANT MITOQ10 AND THE ANGIOTENSIN RECEPTOR BLOCKER LOSARTAN ON CARDIOVASCULAR FUNCTION: 2B.03 Journal of Hypertension. 28: e18. DOI: 10.1097/01.Hjh.0000378273.80521.9C  0.01
2010 Vayalil PK, Diers AR, Zhou F, Murphy MP, Landar A. Role of Krebs Cycle Enzymes in Mediating Changes in Cancer Cell Metabolism Following Mitochondrial Thiol Modification by (4iodobutyl) Triphenylphosphonium Free Radical Biology and Medicine. 49: S173. DOI: 10.1016/J.Freeradbiomed.2010.10.493  0.01
2010 Zhou F, Ricart KC, Vayalil PK, Wall SB, Johnson MS, Murphy MP, Landar A. A Protective Role for Indirect Protein Thiol Modification in Response to 15-deoxy -Δ12,14-Prostaglandin J2 in Endothelial Cells Free Radical Biology and Medicine. 49: S167-S168. DOI: 10.1016/J.Freeradbiomed.2010.10.474  0.01
2010 Eriksen JL, Murphy MP, Head E. Pharmacological Models for Preclinical Testing: From Mouse to Dog to Nonhuman Primates Bace: Lead Target For Orchestrated Therapy of Alzheimer's Disease. 159-175. DOI: 10.1002/9780470594087.ch7  1
2009 Murphy MP, Kim S, Sitti M. Enhanced adhesion by gecko-inspired hierarchical fibrillar adhesives. Acs Applied Materials & Interfaces. 1: 849-55. PMID 20356011 DOI: 10.1021/Am8002439  1
2009 Zuccarello DJ, Murphy MP, Meyer RF, Winslow PA. A comprehensive approach for the determination of extractable and leachable metals in pharmaceutical products by inductively-coupled plasma. Pda Journal of Pharmaceutical Science and Technology / Pda. 63: 339-52. PMID 20088247  1
2009 Mikirova NA, Jackson JA, Hunninghake R, Kenyon J, Chan KW, Swindlehurst CA, Minev B, Patel AN, Murphy MP, Smith L, Alexandrescu DT, Ichim TE, Riordan NH. Circulating endothelial progenitor cells: a new approach to anti-aging medicine? Journal of Translational Medicine. 7: 106. PMID 20003528 DOI: 10.1186/1479-5876-7-106  1
2009 Quin C, Trnka J, Hay A, Murphy MP, Hartley RC. Synthesis of a mitochondria-targeted spin trap using a novel Parham-type cyclization. Tetrahedron. 65: 8154-8160. PMID 19888470 DOI: 10.1016/j.tet.2009.07.081  1
2009 Abdul HM, Sama MA, Furman JL, Mathis DM, Beckett TL, Weidner AM, Patel ES, Baig I, Murphy MP, LeVine H, Kraner SD, Norris CM. Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12957-69. PMID 19828810 DOI: 10.1523/Jneurosci.1064-09.2009  1
2009 Murphy MP. Mitochondria--a neglected drug target. Current Opinion in Investigational Drugs (London, England : 2000). 10: 1022-4. PMID 19777389  1
2009 Supinski GS, Murphy MP, Callahan LA. MitoQ administration prevents endotoxin-induced cardiac dysfunction. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 297: R1095-102. PMID 19657095 DOI: 10.1152/ajpregu.90902.2008  1
2009 Graham D, Huynh NN, Hamilton CA, Beattie E, Smith RA, Cochemé HM, Murphy MP, Dominiczak AF. Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy. Hypertension. 54: 322-8. PMID 19581509 DOI: 10.1161/HYPERTENSIONAHA.109.130351  1
2009 Prime TA, Blaikie FH, Evans C, Nadtochiy SM, James AM, Dahm CC, Vitturi DA, Patel RP, Hiley CR, Abakumova I, Requejo R, Chouchani ET, Hurd TR, Garvey JF, Taylor CT, ... ... Murphy MP, et al. A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury. Proceedings of the National Academy of Sciences of the United States of America. 106: 10764-9. PMID 19528654 DOI: 10.1073/Pnas.0903250106  1
2009 Walters GD, Berry DT, Lanyon RI, Murphy MP. Are exaggerated health complaints continuous or categorical? A taxometric analysis of the Health Problem Overstatement Scale. Psychological Assessment. 21: 219-26. PMID 19485676 DOI: 10.1037/a0015306  1
2009 Wright AF, Murphy MP, Turnbull DM. Do organellar genomes function as long-term redox damage sensors? Trends in Genetics : Tig. 25: 253-61. PMID 19481287 DOI: 10.1016/J.Tig.2009.04.006  1
2009 Liu Y, Studzinski C, Beckett T, Guan H, Hersh MA, Murphy MP, Klein R, Hersh LB. Expression of neprilysin in skeletal muscle reduces amyloid burden in a transgenic mouse model of Alzheimer disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1381-6. PMID 19471248 DOI: 10.1038/Mt.2009.115  1
2009 Jaeger LB, Dohgu S, Hwang MC, Farr SA, Murphy MP, Fleegal-DeMotta MA, Lynch JL, Robinson SM, Niehoff ML, Johnson SN, Kumar VB, Banks WA. Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition. Journal of Alzheimer's Disease : Jad. 17: 553-70. PMID 19433890 DOI: 10.3233/JAD-2009-1074  1
2009 Riordan NH, Ichim TE, Min WP, Wang H, Solano F, Lara F, Alfaro M, Rodriguez JP, Harman RJ, Patel AN, Murphy MP, Lee RR, Minev B. Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis. Journal of Translational Medicine. 7: 29. PMID 19393041 DOI: 10.1186/1479-5876-7-29  1
2009 Lemmon GW, Murphy MP. Dialysis access steal syndromes. Perspectives in Vascular Surgery and Endovascular Therapy. 21: 36-9. PMID 19380391 DOI: 10.1177/1531003509333230  1
2009 Shafique S, Murphy MP, Sawchuk AP, Cikrit D, Dalsing MC. Femoral arterial access management for endovascular aortic aneurysm repair: evolution and outcome. Perspectives in Vascular Surgery and Endovascular Therapy. 21: 29-33. PMID 19364727 DOI: 10.1177/1531003509333580  1
2009 Cochemé HM, Murphy MP. Chapter 22 The uptake and interactions of the redox cycler paraquat with mitochondria. Methods in Enzymology. 456: 395-417. PMID 19348901 DOI: 10.1016/S0076-6879(08)04422-4  1
2009 Hurd TR, James AM, Lilley KS, Murphy MP. Chapter 19 Measuring redox changes to mitochondrial protein thiols with redox difference gel electrophoresis (redox-DIGE). Methods in Enzymology. 456: 343-61. PMID 19348898 DOI: 10.1016/S0076-6879(08)04419-4  1
2009 Zhang Y, Ingram DA, Murphy MP, Saadatzadeh MR, Mead LE, Prater DN, Rehman J. Release of proinflammatory mediators and expression of proinflammatory adhesion molecules by endothelial progenitor cells. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1675-82. PMID 19252096 DOI: 10.1152/Ajpheart.00665.2008  1
2009 Lowes DA, Wallace C, Murphy MP, Webster NR, Galley HF. The mitochondria targeted antioxidant MitoQ protects against fluoroquinolone-induced oxidative stress and mitochondrial membrane damage in human Achilles tendon cells. Free Radical Research. 43: 323-8. PMID 19235604 DOI: 10.1080/10715760902736275  1
2009 Zhong Z, Patel AN, Ichim TE, Riordan NH, Wang H, Min WP, Woods EJ, Reid M, Mansilla E, Marin GH, Drago H, Murphy MP, Minev B. Feasibility investigation of allogeneic endometrial regenerative cells. Journal of Translational Medicine. 7: 15. PMID 19232091 DOI: 10.1186/1479-5876-7-15  1
2009 Eitel JA, Bijangi-Vishehsaraei K, Saadatzadeh MR, Bhavsar JR, Murphy MP, Pollok KE, Mayo LD. PTEN and p53 are required for hypoxia induced expression of maspin in glioblastoma cells. Cell Cycle (Georgetown, Tex.). 8: 896-901. PMID 19221500 DOI: 10.4161/Cc.8.6.7899  1
2009 Han X, Meng X, Yin Z, Rogers A, Zhong J, Rillema P, Jackson JA, Ichim TE, Minev B, Carrier E, Patel AN, Murphy MP, Min WP, Riordan NH. Inhibition of intracranial glioma growth by endometrial regenerative cells. Cell Cycle (Georgetown, Tex.). 8: 606-10. PMID 19197154 DOI: 10.4161/cc.8.4.7731  1
2009 Ricart KC, Bolisetty S, Johnson MS, Perez J, Agarwal A, Murphy MP, Landar A. The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. The Biochemical Journal. 419: 427-36. PMID 19161347 DOI: 10.1042/Bj20081350  1
2009 Distasi MR, Case J, Ziegler MA, Dinauer MC, Yoder MC, Haneline LS, Dalsing MC, Miller SJ, Labarrere CA, Murphy MP, Ingram DA, Unthank JL. Suppressed hindlimb perfusion in Rac2-/- and Nox2-/- mice does not result from impaired collateral growth. American Journal of Physiology. Heart and Circulatory Physiology. 296: H877-86. PMID 19151256 DOI: 10.1152/Ajpheart.00772.2008  1
2009 Murphy MP, Aksak B, Sitti M. Gecko-inspired directional and controllable adhesion. Small (Weinheim An Der Bergstrasse, Germany). 5: 170-5. PMID 19115348 DOI: 10.1002/Smll.200801161  1
2009 Murphy MP. How mitochondria produce reactive oxygen species. The Biochemical Journal. 417: 1-13. PMID 19061483 DOI: 10.1042/BJ20081386  1
2009 Trnka J, Blaikie FH, Logan A, Smith RA, Murphy MP. Antioxidant properties of MitoTEMPOL and its hydroxylamine. Free Radical Research. 43: 4-12. PMID 19058062 DOI: 10.1080/10715760802582183  1
2009 Studzinski CM, Li F, Bruce-Keller AJ, Fernandez-Kim SO, Zhang L, Weidner AM, Markesbery WR, Murphy MP, Keller JN. Effects of short-term Western diet on cerebral oxidative stress and diabetes related factors in APP x PS1 knock-in mice. Journal of Neurochemistry. 108: 860-6. PMID 19046405 DOI: 10.1111/J.1471-4159.2008.05798.X  1
2009 Guan H, Liu Y, Daily A, Police S, Kim MH, Oddo S, LaFerla FM, Pauly JR, Murphy MP, Hersh LB. Peripherally expressed neprilysin reduces brain amyloid burden: a novel approach for treating Alzheimer's disease. Journal of Neuroscience Research. 87: 1462-73. PMID 19021293 DOI: 10.1002/Jnr.21944  1
2009 Maroz A, Anderson RF, Smith RA, Murphy MP. Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: implications for in vivo antioxidant activity. Free Radical Biology & Medicine. 46: 105-9. PMID 18977291 DOI: 10.1016/j.freeradbiomed.2008.09.033  1
2008 Smith RA, Adlam VJ, Blaikie FH, Manas AR, Porteous CM, James AM, Ross MF, Logan A, Cochemé HM, Trnka J, Prime TA, Abakumova I, Jones BA, Filipovska A, Murphy MP. Mitochondria-targeted antioxidants in the treatment of disease. Annals of the New York Academy of Sciences. 1147: 105-11. PMID 19076435 DOI: 10.1196/annals.1427.003  1
2008 Hobbs CE, Murphy MP, Smith RA, Oorschot DE. Neonatal rat hypoxia-ischemia: Effect of the anti-oxidant mitoquinol, and S-PBN. Pediatrics International : Official Journal of the Japan Pediatric Society. 50: 481-8. PMID 18937752 DOI: 10.1111/j.1442-200X.2008.02705.x  1
2008 Lowes DA, Thottakam BM, Webster NR, Murphy MP, Galley HF. The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide-peptidoglycan model of sepsis. Free Radical Biology & Medicine. 45: 1559-65. PMID 18845241 DOI: 10.1016/j.freeradbiomed.2008.09.003  1
2008 Murphy MP, Wang H, Patel AN, Kambhampati S, Angle N, Chan K, Marleau AM, Pyszniak A, Carrier E, Ichim TE, Riordan NH. Allogeneic endometrial regenerative cells: an "Off the shelf solution" for critical limb ischemia? Journal of Translational Medicine. 6: 45. PMID 18713449 DOI: 10.1186/1479-5876-6-45  1
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