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James McCluskey, Ph.D. - Publications

Affiliations: 
2008 University of South Florida, Tampa, FL, United States 
Area:
Toxicology, Occupational Health and Safety, Environmental Sciences, Public Health
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244 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 McWilliam HEG, Mak JYW, Awad W, Zorkau M, Cruz-Gomez S, Lim HJ, Yan Y, Wormald S, Dagley LF, Eckle SBG, Corbett AJ, Liu H, Li S, Reddiex SJJ, Mintern JD, ... ... McCluskey J, et al. Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens. Proceedings of the National Academy of Sciences of the United States of America. PMID 32958637 DOI: 10.1073/Pnas.2011260117  0.352
2020 Awad W, Meermeier EW, Sandoval-Romero ML, Le Nours J, Worley AH, Null MD, Liu L, McCluskey J, Fairlie DP, Lewinsohn DM, Rossjohn J. Atypical TRAV1-2- T cell receptor recognition of the antigen-presenting molecule MR1. The Journal of Biological Chemistry. PMID 32817339 DOI: 10.1074/Jbc.Ra120.015292  0.369
2020 Toubal A, Kiaf B, Beaudoin L, Cagninacci L, Rhimi M, Fruchet B, da Silva J, Corbett AJ, Simoni Y, Lantz O, Rossjohn J, McCluskey J, Lesnik P, Maguin E, Lehuen A. Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity. Nature Communications. 11: 3755. PMID 32709874 DOI: 10.1038/S41467-020-17307-0  0.301
2020 Howson LJ, Awad W, von Borstel A, Lim HJ, McWilliam HEG, Sandoval-Romero ML, Majumdar S, Hamzeh AR, Andrews TD, McDermott DH, Murphy PM, Le Nours J, Mak JYW, Liu L, Fairlie DP, ... McCluskey J, et al. Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in . Science Immunology. 5. PMID 32709702 DOI: 10.1126/Sciimmunol.Abc9492  0.363
2020 Suliman S, Gela A, Mendelsohn SC, Iwany SK, Tamara KL, Mabwe S, Bilek N, Darboe F, Fisher M, Corbett AJ, Kjer-Nielsen L, Eckle SBG, Huang CC, Zhang Z, Lewinsohn DM, ... McCluskey J, et al. Peripheral blood mucosal-associated invariant T (MAIT) cells in tuberculosis patients and healthy Mycobacterium tuberculosis-exposed controls. The Journal of Infectious Diseases. PMID 32267943 DOI: 10.1093/Infdis/Jiaa173  0.366
2020 de Lima Moreira M, Souter MNT, Chen Z, Loh L, McCluskey J, Pellicci DG, Eckle SBG. Hypersensitivities following allergen antigen recognition by unconventional T cells. Allergy. PMID 32181878 DOI: 10.1111/All.14279  0.407
2020 McSharry BP, Samer C, McWilliam HEG, Ashley CL, Yee MB, Steain M, Liu L, Fairlie DP, Kinchington PR, McCluskey J, Abendroth A, Villadangos JA, Rossjohn J, Slobedman B. Virus-Mediated Suppression of the Antigen Presentation Molecule MR1. Cell Reports. 30: 2948-2962.e4. PMID 32130899 DOI: 10.1016/J.Celrep.2020.02.017  0.32
2020 Awad W, Ler GJM, Xu W, Keller AN, Mak JYW, Lim XY, Liu L, Eckle SBG, Le Nours J, McCluskey J, Corbett AJ, Fairlie DP, Rossjohn J. The molecular basis underpinning the potency and specificity of MAIT cell antigens. Nature Immunology. PMID 32123373 DOI: 10.1038/S41590-020-0616-6  0.389
2020 Loh L, Gherardin NA, Sant S, Grzelak L, Crawford JC, Bird NL, Koay HF, van de Sandt CE, Moreira ML, Lappas M, Allen EK, Crowe J, Loudovaris T, Flanagan KL, Quinn KM, ... ... McCluskey J, et al. Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRαβ Clonotypes with Potent Antimicrobial Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 31988181 DOI: 10.4049/Jimmunol.1900774  0.324
2020 Crowther MD, Dolton G, Legut M, Caillaud ME, Lloyd A, Attaf M, Galloway SAE, Rius C, Farrell CP, Szomolay B, Ager A, Parker AL, Fuller A, Donia M, McCluskey J, et al. Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nature Immunology. PMID 31959982 DOI: 10.1038/S41590-019-0578-8  0.379
2019 Petersen J, Ciacchi L, Tran MT, Loh KL, Kooy-Winkelaar Y, Croft NP, Hardy MY, Chen Z, McCluskey J, Anderson RP, Purcell AW, Tye-Din JA, Koning F, Reid HH, Rossjohn J. T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease. Nature Structural & Molecular Biology. PMID 31873306 DOI: 10.1038/S41594-019-0353-4  0.421
2019 Le Nours J, Gherardin NA, Ramarathinam SH, Awad W, Wiede F, Gully BS, Khandokar Y, Praveena T, Wubben JM, Sandow JJ, Webb AI, von Borstel A, Rice MT, Redmond SJ, Seneviratna R, ... McCluskey J, et al. A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1. Science (New York, N.Y.). 366: 1522-1527. PMID 31857486 DOI: 10.1126/Science.Aav3900  0.398
2019 Souter MNT, Loh L, Li S, Meehan BS, Gherardin NA, Godfrey DI, Rossjohn J, Fairlie DP, Kedzierska K, Pellicci DG, Chen Z, Kjer-Nielsen L, Corbett AJ, McCluskey J, Eckle SBG. Characterization of Human Mucosal-associated Invariant T (MAIT) Cells. Current Protocols in Immunology. 127: e90. PMID 31763790 DOI: 10.1002/Cpim.90  0.393
2019 Chen Z, Wang H, D'Souza C, Koay HF, Meehan B, Zhao Z, Pediongco T, Shi M, Zhu T, Wang B, Kjer-Nielsen L, Eckle SBG, Rossjohn J, Fairlie DP, Godfrey DI, ... ... McCluskey J, et al. Characterization and Purification of Mouse Mucosal-Associated Invariant T (MAIT) Cells. Current Protocols in Immunology. 127: e89. PMID 31763782 DOI: 10.1002/Cpim.89  0.353
2019 Koay HF, Su S, Amann-Zalcenstein D, Daley SR, Comerford I, Miosge L, Whyte CE, Konstantinov IE, d'Udekem Y, Baldwin T, Hickey PF, Berzins SP, Mak JYW, Sontani Y, Roots CM, ... ... McCluskey J, et al. A divergent transcriptional landscape underpins the development and functional branching of MAIT cells. Science Immunology. 4. PMID 31757835 DOI: 10.1126/Sciimmunol.Aay6039  0.321
2019 Wang H, Kjer-Nielsen L, Shi M, D'Souza C, Pediongco TJ, Cao H, Kostenko L, Lim XY, Eckle SBG, Meehan BS, Zhu T, Wang B, Zhao Z, Mak JYW, Fairlie DP, ... ... McCluskey J, et al. IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection. Science Immunology. 4. PMID 31732518 DOI: 10.1126/Sciimmunol.Aaw0402  0.343
2019 Hinks TSC, Marchi E, Jabeen M, Olshansky M, Kurioka A, Pediongco TJ, Meehan BS, Kostenko L, Turner SJ, Corbett AJ, Chen Z, Klenerman P, McCluskey J. Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality. Cell Reports. 28: 3249-3262.e5. PMID 31533045 DOI: 10.1016/J.Celrep.2019.07.039  0.357
2019 Chan J, Soraya GV, Craig L, Uddin SM, Todaro M, Huynh DH, Abeyrathne CD, Kostenko L, McCluskey J, Skafidas E, Kwan P. Rapid Detection of HLA-B*57:01-Expressing Cells Using a Label-Free Interdigitated Electrode Biosensor Platform for Prevention of Abacavir Hypersensitivity in HIV Treatment. Sensors (Basel, Switzerland). 19. PMID 31416185 DOI: 10.3390/S19163543  0.327
2019 Godfrey DI, Koay HF, McCluskey J, Gherardin NA. The biology and functional importance of MAIT cells. Nature Immunology. 20: 1110-1128. PMID 31406380 DOI: 10.1038/S41590-019-0444-8  0.413
2019 Koay HF, Gherardin NA, Xu C, Seneviratna R, Zhao Z, Chen Z, Fairlie DP, McCluskey J, Pellicci DG, Uldrich AP, Godfrey DI. Diverse MR1-restricted T cells in mice and humans. Nature Communications. 10: 2243. PMID 31113973 DOI: 10.1038/S41467-019-10198-W  0.403
2019 Neier SC, Ferrer A, Wilton KM, Smith SEP, Kelcher AMH, Pavelko KD, Canfield JM, Davis TR, Stiles RJ, Chen Z, McCluskey J, Burrows SR, Rossjohn J, Hebrink DM, Carmona EM, et al. The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network. Science Immunology. 4. PMID 30770409 DOI: 10.1126/Sciimmunol.Aal2201  0.31
2019 Pulster EL, Johnson G, Hollander D, McCluskey J, Harbison R. Levels and Sources of Atmospheric Polycyclic Aromatic Hydrocarbons Surrounding an Oil Refinery in Curaçao Journal of Environmental Protection. 10: 431-453. DOI: 10.4236/Jep.2019.103025  0.712
2019 Pulster EL, Johnson G, McCluskey J, Harbison RD. Public health risk analysis for ambient polycyclic aromatic hydrocarbon exposure surrounding a petrochemical complex in Curaçao Human and Ecological Risk Assessment: An International Journal. 26: 2173-2188. DOI: 10.1080/10807039.2019.1660140  0.726
2018 Illing PT, Pymm P, Croft NP, Hilton HG, Jojic V, Han AS, Mendoza JL, Mifsud NA, Dudek NL, McCluskey J, Parham P, Rossjohn J, Vivian JP, Purcell AW. HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nature Communications. 9: 4693. PMID 30410026 DOI: 10.1038/S41467-018-07109-W  0.351
2018 Gherardin NA, McCluskey J, Rossjohn J, Godfrey DI. The Diverse Family of MR1-Restricted T Cells. Journal of Immunology (Baltimore, Md. : 1950). 201: 2862-2871. PMID 30397170 DOI: 10.4049/Jimmunol.1801091  0.359
2018 Wang H, D'Souza C, Lim XY, Kostenko L, Pediongco TJ, Eckle SBG, Meehan BS, Shi M, Wang N, Li S, Liu L, Mak JYW, Fairlie DP, Iwakura Y, Gunnersen JM, ... ... McCluskey J, et al. MAIT cells protect against pulmonary Legionella longbeachae infection. Nature Communications. 9: 3350. PMID 30135490 DOI: 10.1038/S41467-018-05202-8  0.332
2018 Kjer-Nielsen L, Corbett AJ, Chen Z, Liu L, Mak JYW, Godfrey DI, Rossjohn J, Fairlie DP, McCluskey J, Eckle SBG. An overview on the identification of MAIT cell antigens. Immunology and Cell Biology. PMID 29656544 DOI: 10.1111/Imcb.12057  0.394
2018 Varelias A, Bunting MD, Ormerod KL, Koyama M, Olver SD, Straube J, Kuns RD, Robb RJ, Henden AS, Cooper L, Lachner N, Gartlan KH, Lantz O, Kjer-Nielsen L, Mak JY, ... ... McCluskey J, et al. Recipient mucosal-associated invariant T cells control GVHD within the colon. The Journal of Clinical Investigation. PMID 29629900 DOI: 10.1172/Jci91646  0.328
2018 Coyle JP, Rinaldi RJ, Johnson GT, Bourgeois MM, McCluskey JD, Harbison RD. Reduced oxygen tension culturing conditionally alters toxicogenic response of differentiated H9c2 cardiomyoblasts to acrolein. Toxicology Mechanisms and Methods. 1-39. PMID 29564938 DOI: 10.1080/15376516.2018.1455785  0.699
2018 Chan KF, Gully BS, Gras S, Beringer DX, Kjer-Nielsen L, Cebon J, McCluskey J, Chen W, Rossjohn J. Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide. Nature Communications. 9: 1026. PMID 29531227 DOI: 10.1038/S41467-018-03321-W  0.404
2018 Gherardin NA, Loh L, Admojo L, Davenport AJ, Richardson K, Rogers A, Darcy PK, Jenkins MR, Prince HM, Harrison SJ, Quach H, Fairlie DP, Kedzierska K, McCluskey J, Uldrich AP, et al. Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma. Scientific Reports. 8: 4159. PMID 29515123 DOI: 10.1038/S41598-018-22130-1  0.366
2018 Gherardin NA, Souter MNT, Koay HF, Mangas KM, Seemann T, Stinear TP, Eckle SBG, Berzins SP, d'Udekem Y, Konstantinov IE, Fairlie DP, Ritchie DS, Neeson PJ, Pellicci DG, Uldrich AP, ... McCluskey J, et al. Human blood MAIT cell subsets defined using MR1 tetramers. Immunology and Cell Biology. PMID 29437263 DOI: 10.1111/Imcb.12021  0.365
2018 Awad W, Le Nours J, Kjer-Nielsen L, McCluskey J, Rossjohn J. Mucosal-Associated Invariant T cell receptor recognition of small molecules presented by MR1. Immunology and Cell Biology. PMID 29393543 DOI: 10.1111/Imcb.12017  0.381
2018 D'Souza C, Pediongco T, Wang H, Scheerlinck JY, Kostenko L, Esterbauer R, Stent AW, Eckle SBG, Meehan BS, Strugnell RA, Cao H, Liu L, Mak JYW, Lovrecz G, Lu L, ... ... McCluskey J, et al. Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 29378910 DOI: 10.4049/Jimmunol.1701512  0.303
2018 Pulster EL, Johnson G, Hollander D, McCluskey J, Harbison R. Exposure Assessment of Ambient Sulfur Dioxide Downwind of an Oil Refinery in Curaçao Journal of Environmental Protection. 9: 194-210. DOI: 10.4236/Jep.2018.93014  0.728
2018 Pulster EL, Johnson G, Hollander D, McCluskey J, Harbison R. Assessment of Inhalable Particulate Matter Associated with a Refinery in Curaçao Journal of Environmental Protection. 9: 1113-1128. DOI: 10.4236/Jep.2018.910069  0.724
2018 Hinks T, Wilgenburg Bv, Loh L, Chen Z, Pediongco T, Wang H, Shi M, Zhao Z, Koutsakos M, Nussing S, Sant S, Wang Z, D’Souza C, Almeida C, Reading P, ... ... Mccluskey J, et al. Mait Cells Contribute To A Protective Antiviral Innate Response To Influenza Infection European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Pa5459  0.318
2017 Rouxel O, Da Silva J, Beaudoin L, Nel I, Tard C, Cagninacci L, Kiaf B, Oshima M, Diedisheim M, Salou M, Corbett A, Rossjohn J, McCluskey J, Scharfmann R, Battaglia M, et al. Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes. Nature Immunology. PMID 28991267 DOI: 10.1038/Ni.3854  0.345
2017 Coyle JP, Rinaldi RJ, Johnson GT, Bourgeois MM, McCluskey J, Harbison RD. Acrolein measurement and degradation in Dulbecco's Modified Eagle Medium: An examination of in-vitro exposure metrics. Toxicology Mechanisms and Methods. 1-21. PMID 28826359 DOI: 10.1080/15376516.2017.1370755  0.725
2017 McCluskey J, Kanaan C, Diviney M. Nomenclature and Serology of HLA Class I and Class II Alleles. Current Protocols in Immunology. 118: A.1S.1-A.1S.6. PMID 28762487 DOI: 10.1002/Cpim.32  0.359
2017 Illing PT, Purcell AW, McCluskey J. The role of HLA genes in pharmacogenomics: unravelling HLA associated adverse drug reactions. Immunogenetics. PMID 28695285 DOI: 10.1007/S00251-017-1007-5  0.34
2017 Shaler CR, Choi J, Rudak PT, Memarnejadian A, Szabo PA, Tun-Abraham ME, Rossjohn J, Corbett AJ, McCluskey J, McCormick JK, Lantz O, Hernandez-Alejandro R, Haeryfar SMM. MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression. Plos Biology. 15: e2001930. PMID 28632753 DOI: 10.1371/Journal.Pbio.2001930  0.38
2017 Keller AN, Corbett AJ, Wubben JM, McCluskey J, Rossjohn J. MAIT cells and MR1-antigen recognition. Current Opinion in Immunology. 46: 66-74. PMID 28494326 DOI: 10.1016/J.Coi.2017.04.002  0.403
2017 Mak JY, Xu W, Reid RC, Corbett AJ, Meehan BS, Wang H, Chen Z, Rossjohn J, McCluskey J, Liu L, Fairlie DP. Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells. Nature Communications. 8: 14599. PMID 28272391 DOI: 10.1038/Ncomms14599  0.398
2017 Keller AN, Eckle SB, Xu W, Liu L, Hughes VA, Mak JY, Meehan BS, Pediongco T, Birkinshaw RW, Chen Z, Wang H, D'Souza C, Kjer-Nielsen L, Gherardin NA, Godfrey DI, ... ... McCluskey J, et al. Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. Nature Immunology. PMID 28166217 DOI: 10.1038/Ni.3679  0.336
2017 Desai U, Johnson GT, McCluskey JD, Harbison RD. Evaluation of Spirometry for Medical Clearance in Occupations Requiring Respirator Usage Occupational Diseases and Environmental Medicine. 5: 67-77. DOI: 10.4236/odem.2017.53007  0.685
2016 Koay HF, Gherardin NA, Enders A, Loh L, Mackay LK, Almeida CF, Russ BE, Nold-Petry CA, Nold MF, Bedoui S, Chen Z, Corbett AJ, Eckle SB, Meehan B, d'Udekem Y, ... ... McCluskey J, et al. A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage. Nature Immunology. PMID 27668799 DOI: 10.1038/Ni.3565  0.349
2016 Loh L, Wang Z, Sant S, Koutsakos M, Jegaskanda S, Corbett AJ, Liu L, Fairlie DP, Crowe J, Rossjohn J, Xu J, Doherty PC, McCluskey J, Kedzierska K. Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27543331 DOI: 10.1073/Pnas.1610750113  0.329
2016 Meermeier EW, Laugel BF, Sewell AK, Corbett AJ, Rossjohn J, McCluskey J, Harriff MJ, Franks T, Gold MC, Lewinsohn DM. Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens. Nature Communications. 7: 12506. PMID 27527800 DOI: 10.1038/Ncomms12506  0.392
2016 Chen Z, Wang H, D'Souza C, Sun S, Kostenko L, Eckle SB, Meehan BS, Jackson DC, Strugnell RA, Cao H, Wang N, Fairlie DP, Liu L, Godfrey DI, Rossjohn J, ... McCluskey J, et al. Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals. Mucosal Immunology. PMID 27143301 DOI: 10.1038/Mi.2016.39  0.336
2016 White J, Wrzesinski C, Green M, Johnson GT, McCluskey JD, Abritis A, Harbison RD. A novel method for deriving thresholds of toxicological concern for vaccine constituents. Toxicology Mechanisms and Methods. 1-6. PMID 27098016 DOI: 10.3109/15376516.2016.1170250  0.706
2016 Rodríguez-Rodríguez N, Apostolidis SA, Fitzgerald L, Meehan BS, Corbett AJ, Martín-Villa JM, McCluskey J, Tsokos GC, Crispín JC. Pro-inflammatory self-reactive T cells are found within murine TCR-αβ(+) CD4(-) CD8(-) PD-1(+) cells. European Journal of Immunology. PMID 27060346 DOI: 10.1002/Eji.201546056  0.338
2016 McWilliam HE, Eckle SB, Theodossis A, Liu L, Chen Z, Wubben JM, Fairlie DP, Strugnell RA, Mintern JD, McCluskey J, Rossjohn J, Villadangos JA. The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1. Nature Immunology. PMID 27043408 DOI: 10.1038/Ni.3416  0.35
2016 Godfrey DI, Uldrich AP, McCluskey J, Rossjohn J, Moody DB. Corrigendum: The burgeoning family of unconventional T cells. Nature Immunology. 17: 469. PMID 27002846 DOI: 10.1038/Ni0416-469A  0.302
2016 Vinton C, Wu F, Rossjohn J, Matsuda K, McCluskey J, Hirsch V, Price DA, Brenchley JM. MAIT cells are systemically depleted in SIV-infected rhesus macaques. Journal of Virology. PMID 26912615 DOI: 10.1128/Jvi.02876-15  0.322
2016 Gherardin NA, Keller AN, Woolley RE, Le Nours J, Ritchie DS, Neeson PJ, Birkinshaw RW, Eckle SB, Waddington JN, Liu L, Fairlie DP, Uldrich AP, Pellicci DG, McCluskey J, Godfrey DI, et al. Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition. Immunity. 44: 32-45. PMID 26795251 DOI: 10.1016/J.Immuni.2015.12.005  0.386
2016 Godfrey DI, Uldrich AP, McCluskey J, Rossjohn J, Moody DB. Corrigendum: The burgeoning family of unconventional T cells. Nature Immunology. 17: 214. PMID 26784266 DOI: 10.1038/Ni0216-214A  0.306
2016 White J, Wrzesinski C, Green M, Johnson GT, McCluskey JD, Abritis A, Harbison RD. A novel method for deriving thresholds of toxicological concern for vaccine constituents Toxicology Mechanisms and Methods. 1-6. DOI: 10.3109/15376516.2016.1170250  0.706
2016 Godfrey D, Koay HF, Gherardin N, Enders A, Loh L, Chen Z, Corbett A, Eckle S, Meehan B, d'Udekem Y, Konstantinov I, Lappas M, Liu L, Goodnow C, Fairlie D, ... ... McCluskey J, et al. Thymic precursors to the mucosal-associated invariant T cell lineage European Journal of Immunology. 46: 256-257. DOI: 10.1002/Eji.201670015  0.341
2015 Godfrey DI, Uldrich AP, McCluskey J, Rossjohn J, Moody DB. The burgeoning family of unconventional T cells. Nature Immunology. 16: 1114-23. PMID 26482978 DOI: 10.1038/Ni.3298  0.399
2015 Eckle SB, Corbett AJ, Keller A, Chen Z, Godfrey DI, Liu L, Mak JY, Fairlie DP, Rossjohn J, McCluskey J. Recognition of Vitamin B precursors and byproducts by Mucosal Associated Invariant T cells. The Journal of Biological Chemistry. PMID 26468291 DOI: 10.1074/Jbc.R115.685990  0.397
2015 Beringer DX, Kleijwegt FS, Wiede F, van der Slik AR, Loh KL, Petersen J, Dudek NL, Duinkerken G, Laban S, Joosten A, Vivian JP, Chen Z, Uldrich AP, Godfrey DI, McCluskey J, et al. T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex. Nature Immunology. PMID 26437244 DOI: 10.1038/Ni.3271  0.393
2015 Okada S, Markle JG, Deenick EK, Mele F, Averbuch D, Lagos M, Alzahrani M, Al-Muhsen S, Halwani R, Ma CS, Wong N, Soudais C, Henderson LA, Marzouqa H, Shamma J, ... ... McCluskey J, et al. IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations. Science (New York, N.Y.). 349: 606-13. PMID 26160376 DOI: 10.1126/Science.Aaa4282  0.303
2015 Rahimpour A, Koay HF, Enders A, Clanchy R, Eckle SB, Meehan B, Chen Z, Whittle B, Liu L, Fairlie DP, Goodnow CC, McCluskey J, Rossjohn J, Uldrich AP, Pellicci DG, et al. Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers. The Journal of Experimental Medicine. 212: 1095-108. PMID 26101265 DOI: 10.1084/Jem.20142110  0.332
2015 Sakala IG, Kjer-Nielsen L, Eickhoff CS, Wang X, Blazevic A, Liu L, Fairlie DP, Rossjohn J, McCluskey J, Fremont DH, Hansen TH, Hoft DF. Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites. Journal of Immunology (Baltimore, Md. : 1950). 195: 587-601. PMID 26063000 DOI: 10.4049/Jimmunol.1402545  0.349
2015 Wilson RP, Ives ML, Rao G, Lau A, Payne K, Kobayashi M, Arkwright PD, Peake J, Wong M, Adelstein S, Smart JM, French MA, Fulcher DA, Picard C, Bustamante J, ... ... McCluskey J, et al. STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function. The Journal of Experimental Medicine. 212: 855-64. PMID 25941256 DOI: 10.1084/Jem.20141992  0.338
2015 McWilliam HE, Birkinshaw RW, Villadangos JA, McCluskey J, Rossjohn J. MR1 presentation of vitamin B-based metabolite ligands. Current Opinion in Immunology. 34: 28-34. PMID 25603223 DOI: 10.1016/J.Coi.2014.12.004  0.356
2015 Miles JJ, McCluskey J, Rossjohn J, Gras S. Understanding the complexity and malleability of T-cell recognition. Immunology and Cell Biology. 93: 433-41. PMID 25582337 DOI: 10.1038/Icb.2014.112  0.392
2015 Rossjohn J, Gras S, Miles JJ, Turner SJ, Godfrey DI, McCluskey J. T cell antigen receptor recognition of antigen-presenting molecules. Annual Review of Immunology. 33: 169-200. PMID 25493333 DOI: 10.1146/Annurev-Immunol-032414-112334  0.411
2015 Gras S, Chabrol E, Eckle SBG, Boer Rd, McCluskey J, Rossjohn J, Heemskerk MHM. The molecular bases of δβ T-cell mediated antigen recognition Acta Crystallographica Section A. 71. DOI: 10.1107/S2053273315096394  0.369
2014 Pellicci DG, Uldrich AP, Le Nours J, Ross F, Chabrol E, Eckle SB, de Boer R, Lim RT, McPherson K, Besra G, Howell AR, Moretta L, McCluskey J, Heemskerk MH, Gras S, et al. The molecular bases of δ/αβ T cell-mediated antigen recognition. The Journal of Experimental Medicine. 211: 2599-615. PMID 25452463 DOI: 10.1084/Jem.20141764  0.384
2014 Nivarthi UK, Gras S, Kjer-Nielsen L, Berry R, Lucet IS, Miles JJ, Tracy SL, Purcell AW, Bowden DS, Hellard M, Rossjohn J, McCluskey J, Bharadwaj M. An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant. Journal of Immunology (Baltimore, Md. : 1950). 193: 5402-13. PMID 25355921 DOI: 10.4049/Jimmunol.1401357  0.319
2014 McCluskey JD, Harbison SC, Johnson GT, Xu P, Morris S, Wolfson J, Harbison RD. Occupational health surveillance: Pulmonary function testing in emergency responders. Journal of Emergencies, Trauma, and Shock. 7: 180-5. PMID 25114428 DOI: 10.4103/0974-2700.136861  0.713
2014 Eckle SB, Birkinshaw RW, Kostenko L, Corbett AJ, McWilliam HE, Reantragoon R, Chen Z, Gherardin NA, Beddoe T, Liu L, Patel O, Meehan B, Fairlie DP, Villadangos JA, Godfrey DI, ... ... McCluskey J, et al. A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells. The Journal of Experimental Medicine. 211: 1585-600. PMID 25049336 DOI: 10.1084/Jem.20140484  0.374
2014 McCluskey J, Bourgeois M, Harbison R. Tulipalin A induced phytotoxicity. International Journal of Critical Illness and Injury Science. 4: 181-3. PMID 25024947 DOI: 10.4103/2229-5151.134187  0.549
2014 Liu YC, Chen Z, Neller MA, Miles JJ, Purcell AW, McCluskey J, Burrows SR, Rossjohn J, Gras S. A molecular basis for the interplay between T cells, viral mutants, and human leukocyte antigen micropolymorphism. The Journal of Biological Chemistry. 289: 16688-98. PMID 24759101 DOI: 10.1074/Jbc.M114.563502  0.395
2014 Corbett AJ, Eckle SB, Birkinshaw RW, Liu L, Patel O, Mahony J, Chen Z, Reantragoon R, Meehan B, Cao H, Williamson NA, Strugnell RA, Van Sinderen D, Mak JY, Fairlie DP, ... McCluskey J, et al. T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature. 509: 361-5. PMID 24695216 DOI: 10.1038/Nature13160  0.388
2014 Birkinshaw RW, Kjer-Nielsen L, Eckle SB, McCluskey J, Rossjohn J. MAITs, MR1 and vitamin B metabolites. Current Opinion in Immunology. 26: 7-13. PMID 24556396 DOI: 10.1016/J.Coi.2013.09.007  0.412
2014 Lichtenfels M, Farrell J, Ogese MO, Bell CC, Eckle S, McCluskey J, Park BK, Alfirevic A, Naisbitt DJ, Pirmohamed M. HLA restriction of carbamazepine-specific T-Cell clones from an HLA-A*31:01-positive hypersensitive patient. Chemical Research in Toxicology. 27: 175-7. PMID 24476427 DOI: 10.1021/Tx400460W  0.392
2014 Bhati M, Cole DK, McCluskey J, Sewell AK, Rossjohn J. The versatility of the αβ T-cell antigen receptor. Protein Science : a Publication of the Protein Society. 23: 260-72. PMID 24375592 DOI: 10.1002/Pro.2412  0.403
2014 Johnson GT, Morris S, McCluskey JD, Xu P, Harbison RD. Pesticide Biomonitoring in Florida Agricultural Workers Occupational Diseases and Environmental Medicine. 2: 30-38. DOI: 10.4236/odem.2014.22004  0.693
2014 Pellicci DG, Uldrich AP, Nours JL, Ross F, Chabrol E, Eckle SBG, Boer Rd, Lim RT, McPherson K, Besra G, Howell AR, Moretta L, McCluskey J, Heemskerk MHM, Gras S, et al. The molecular bases of delta/alpha beta T cell-mediated antigen recognition Journal of Experimental Medicine. 211: 2599-2615. DOI: 10.2210/Pdb4Wnq/Pdb  0.307
2014 Illing P, Mifsud N, Croft N, Dudek N, McCluskey J, Purcell A. Using mass spectrometry to monitor drug induced changes in antigen presentation by the human leukocyte antigen Clinical and Translational Allergy. 4: 43. DOI: 10.1186/2045-7022-4-S3-P43  0.403
2014 Lichtenfels M, Farrell J, Ogese M, Bell C, Eckle S, McCluskey J, Park K, Alfirevic A, Naisbitt D, Pirmohamed M. Abs No: HLA-A*31:01 positive hypersensitive patient Clinical and Translational Allergy. 4: 117. DOI: 10.1186/2045-7022-4-S3-P117  0.372
2013 Scally SW, Petersen J, Law SC, Dudek NL, Nel HJ, Loh KL, Wijeyewickrema LC, Eckle SB, van Heemst J, Pike RN, McCluskey J, Toes RE, La Gruta NL, Purcell AW, Reid HH, et al. A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. The Journal of Experimental Medicine. 210: 2569-82. PMID 24190431 DOI: 10.1084/Jem.20131241  0.365
2013 Reantragoon R, Corbett AJ, Sakala IG, Gherardin NA, Furness JB, Chen Z, Eckle SB, Uldrich AP, Birkinshaw RW, Patel O, Kostenko L, Meehan B, Kedzierska K, Liu L, Fairlie DP, ... ... McCluskey J, et al. Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. The Journal of Experimental Medicine. 210: 2305-20. PMID 24101382 DOI: 10.1084/Jem.20130958  0.346
2013 Eckle SB, Turner SJ, Rossjohn J, McCluskey J. Predisposed αβ T cell antigen receptor recognition of MHC and MHC-I like molecules? Current Opinion in Immunology. 25: 653-9. PMID 23993410 DOI: 10.1016/J.Coi.2013.07.010  0.387
2013 Patel O, Kjer-Nielsen L, Le Nours J, Eckle SB, Birkinshaw R, Beddoe T, Corbett AJ, Liu L, Miles JJ, Meehan B, Reantragoon R, Sandoval-Romero ML, Sullivan LC, Brooks AG, Chen Z, ... ... McCluskey J, et al. Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nature Communications. 4: 2142. PMID 23846752 DOI: 10.1038/Ncomms3142  0.363
2013 Rist MJ, Theodossis A, Croft NP, Neller MA, Welland A, Chen Z, Sullivan LC, Burrows JM, Miles JJ, Brennan RM, Gras S, Khanna R, Brooks AG, McCluskey J, Purcell AW, et al. HLA peptide length preferences control CD8+ T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 191: 561-71. PMID 23749632 DOI: 10.4049/Jimmunol.1300292  0.347
2013 Liu YC, Miles JJ, Neller MA, Gostick E, Price DA, Purcell AW, McCluskey J, Burrows SR, Rossjohn J, Gras S. Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule. The Journal of Biological Chemistry. 288: 15442-54. PMID 23569211 DOI: 10.1074/Jbc.M112.447185  0.387
2013 Illing PT, Vivian JP, Purcell AW, Rossjohn J, McCluskey J. Human leukocyte antigen-associated drug hypersensitivity. Current Opinion in Immunology. 25: 81-9. PMID 23141566 DOI: 10.1016/J.Coi.2012.10.002  0.324
2012 Broughton SE, Petersen J, Theodossis A, Scally SW, Loh KL, Thompson A, van Bergen J, Kooy-Winkelaar Y, Henderson KN, Beddoe T, Tye-Din JA, Mannering SI, Purcell AW, McCluskey J, Anderson RP, et al. Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease. Immunity. 37: 611-21. PMID 23063329 DOI: 10.1016/J.Immuni.2012.07.013  0.389
2012 Kjer-Nielsen L, Patel O, Corbett AJ, Le Nours J, Meehan B, Liu L, Bhati M, Chen Z, Kostenko L, Reantragoon R, Williamson NA, Purcell AW, Dudek NL, McConville MJ, O'Hair RA, ... McCluskey J, et al. MR1 presents microbial vitamin B metabolites to MAIT cells. Nature. 491: 717-23. PMID 23051753 DOI: 10.1038/Nature11605  0.387
2012 Gras S, Burrows SR, Turner SJ, Sewell AK, McCluskey J, Rossjohn J. A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned. Immunological Reviews. 250: 61-81. PMID 23046123 DOI: 10.1111/J.1600-065X.2012.01159.X  0.416
2012 Illing PT, Vivian JP, Dudek NL, Kostenko L, Chen Z, Bharadwaj M, Miles JJ, Kjer-Nielsen L, Gras S, Williamson NA, Burrows SR, Purcell AW, Rossjohn J, McCluskey J. Immune self-reactivity triggered by drug-modified HLA-peptide repertoire. Nature. 486: 554-8. PMID 22722860 DOI: 10.1038/Nature11147  0.379
2012 Bharadwaj M, Mifsud NA, McCluskey J. Detection and characterisation of alloreactive T cells. Methods in Molecular Biology (Clifton, N.J.). 882: 309-37. PMID 22665242 DOI: 10.1007/978-1-61779-842-9_18  0.327
2012 Reantragoon R, Kjer-Nielsen L, Patel O, Chen Z, Illing PT, Bhati M, Kostenko L, Bharadwaj M, Meehan B, Hansen TH, Godfrey DI, Rossjohn J, McCluskey J. Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor. The Journal of Experimental Medicine. 209: 761-74. PMID 22412157 DOI: 10.1084/Jem.20112095  0.369
2012 Liu YC, Chen Z, Burrows SR, Purcell AW, McCluskey J, Rossjohn J, Gras S. The energetic basis underpinning T-cell receptor recognition of a super-bulged peptide bound to a major histocompatibility complex class I molecule. The Journal of Biological Chemistry. 287: 12267-76. PMID 22343629 DOI: 10.1074/Jbc.M112.344689  0.378
2012 Brennan RM, Petersen J, Neller MA, Miles JJ, Burrows JM, Smith C, McCluskey J, Khanna R, Rossjohn J, Burrows SR. The impact of a large and frequent deletion in the human TCR β locus on antiviral immunity. Journal of Immunology (Baltimore, Md. : 1950). 188: 2742-8. PMID 22323539 DOI: 10.4049/Jimmunol.1102675  0.395
2012 Radcliff FJ, Loh JM, Ha B, Schuhbauer D, McCluskey J, Fraser JD. Antigen targeting to major histocompatibility complex class II with streptococcal mitogenic exotoxin Z-2 M1, a superantigen-based vaccine carrier. Clinical and Vaccine Immunology : Cvi. 19: 574-86. PMID 22301693 DOI: 10.1128/Cvi.05446-11  0.376
2012 Gras S, Wilmann PG, Chen Z, Halim H, Liu YC, Kjer-Nielsen L, Purcell AW, Burrows SR, McCluskey J, Rossjohn J. A structural basis for varied αβ TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule. Journal of Immunology (Baltimore, Md. : 1950). 188: 311-21. PMID 22140258 DOI: 10.4049/Jimmunol.1102686  0.386
2012 Bharadwaj M, Illing P, Theodossis A, Purcell AW, Rossjohn J, McCluskey J. Drug hypersensitivity and human leukocyte antigens of the major histocompatibility complex. Annual Review of Pharmacology and Toxicology. 52: 401-31. PMID 22017685 DOI: 10.1146/Annurev-Pharmtox-010611-134701  0.355
2012 McCluskey J, Bourgeois M, Harbison R. A Case of Mistaken Identity - Ocular Histoplasmosis in Florida Journal of Clinical Toxicology. 2013: 0-0. DOI: 10.4172/2161-0495.S5-007  0.529
2012 Reantragoon R, Kjer-Nielsen L, Patel O, Illing P, Godfrey D, Rossjohn J, McCluskey J. A structural basis for selection of the mucosal associated invariant T cell receptor in MR1-restricted antigen recognition Molecular Immunology. 51: 25. DOI: 10.1016/J.Molimm.2012.02.066  0.362
2012 Illing P, Vivian J, Dudek N, Kostenko L, Chen Z, Bharadwaj M, Kjer-Nielsen L, Purcell A, Rossjohn J, McCluskey J. Immune self-reactivity triggered by drug-modified human leukocyte antigen-peptide presentation Molecular Immunology. 51: 19. DOI: 10.1016/J.Molimm.2012.02.048  0.301
2011 McCluskey JD, Sava D, Harbison SC, Muro-Cacho CA, Giffe JT, Ping X, Harbison RD. Hepatoprotective effects of select water-soluble PARP inhibitors in a carbon tetrachloride model. International Journal of Critical Illness and Injury Science. 1: 97-103. PMID 22229131 DOI: 10.4103/2229-5151.84788  0.463
2011 Patel O, Pellicci DG, Uldrich AP, Sullivan LC, Bhati M, McKnight M, Richardson SK, Howell AR, Mallevaey T, Zhang J, Bedel R, Besra GS, Brooks AG, Kjer-Nielsen L, McCluskey J, et al. Vβ2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen. Proceedings of the National Academy of Sciences of the United States of America. 108: 19007-12. PMID 22065767 DOI: 10.1073/Pnas.1109066108  0.351
2011 Pellicci DG, Clarke AJ, Patel O, Mallevaey T, Beddoe T, Le Nours J, Uldrich AP, McCluskey J, Besra GS, Porcelli SA, Gapin L, Godfrey DI, Rossjohn J. Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors. Nature Immunology. 12: 827-33. PMID 21804559 DOI: 10.1038/Ni.2076  0.332
2011 Uldrich AP, Patel O, Cameron G, Pellicci DG, Day EB, Sullivan LC, Kyparissoudis K, Kjer-Nielsen L, Vivian JP, Cao B, Brooks AG, Williams SJ, Illarionov P, Besra GS, Turner SJ, ... McCluskey J, et al. A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties. Nature Immunology. 12: 616-23. PMID 21666690 DOI: 10.1038/Ni.2051  0.409
2011 Kostenko L, Kjer-Nielsen L, Nicholson I, Hudson F, Lucas A, Foley B, Chen K, Lynch K, Nguyen J, Wu AHB, Tait BD, Holdsworth R, Mallal S, Rossjohn J, Bharadwaj M, ... McCluskey J, et al. Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity Tissue Antigens. 78: 11-20. PMID 21501118 DOI: 10.1111/J.1399-0039.2011.01649.X  0.318
2011 Mallevaey T, Clarke AJ, Scott-Browne JP, Young MH, Roisman LC, Pellicci DG, Patel O, Vivian JP, Matsuda JL, McCluskey J, Godfrey DI, Marrack P, Rossjohn J, Gapin L. A molecular basis for NKT cell recognition of CD1d-self-antigen. Immunity. 34: 315-26. PMID 21376640 DOI: 10.1016/J.Immuni.2011.01.013  0.328
2011 Wun KS, Cameron G, Patel O, Pang SS, Pellicci DG, Sullivan LC, Keshipeddy S, Young MH, Uldrich AP, Thakur MS, Richardson SK, Howell AR, Illarionov PA, Brooks AG, Besra GS, ... McCluskey J, et al. A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells. Immunity. 34: 327-39. PMID 21376639 DOI: 10.1016/J.Immuni.2011.02.001  0.381
2011 Berry R, Chen Z, McCluskey J, Rossjohn J. Insight into the basis of autonomous immunoreceptor activation. Trends in Immunology. 32: 165-70. PMID 21354859 DOI: 10.1016/J.It.2011.01.007  0.36
2011 Gras S, Kjer-Nielsen L, Chen Z, Rossjohn J, McCluskey J. The structural bases of direct T-cell allorecognition: implications for T-cell-mediated transplant rejection. Immunology and Cell Biology. 89: 388-95. PMID 21301478 DOI: 10.1038/Icb.2010.150  0.395
2011 D'Orsogna LJ, Roelen DL, van der Meer-Prins EM, van der Pol P, Franke-van Dijk ME, Eikmans M, Anholts J, Rossjohn J, McCluskey J, Mulder A, van Kooten C, Doxiadis II, Claas FH. Tissue specificity of cross-reactive allogeneic responses by EBV EBNA3A-specific memory T cells. Transplantation. 91: 494-500. PMID 21242884 DOI: 10.1097/Tp.0B013E318207944C  0.4
2011 Bade-Döding C, Theodossis A, Gras S, Kjer-Nielsen L, Eiz-Vesper B, Seltsam A, Huyton T, Rossjohn J, McCluskey J, Blasczyk R. The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family. Haematologica. 96: 110-8. PMID 20934997 DOI: 10.3324/Haematol.2010.030924  0.391
2011 Mccluskey J. Update on T-cell immunity: Implications for tumor immunology Asia-Pacific Journal of Clinical Oncology. 7: 3-8. DOI: 10.1111/J.1743-7563.2011.01381.X  0.348
2011 Eckle S, Gras S, Kjer-Nielsen L, Smith C, Khanna R, Rossjohn J, McCluskey J. MHC class I and class II reactivity mediated by a single T cell receptor Acta Crystallographica Section A. 67: 544-544. DOI: 10.1107/S0108767311086260  0.346
2010 Pang SS, Berry R, Chen Z, Kjer-Nielsen L, Perugini MA, King GF, Wang C, Chew SH, La Gruta NL, Williams NK, Beddoe T, Tiganis T, Cowieson NP, Godfrey DI, Purcell AW, ... ... McCluskey J, et al. The structural basis for autonomous dimerization of the pre-T-cell antigen receptor. Nature. 467: 844-8. PMID 20944746 DOI: 10.1038/nature09448  0.35
2010 Tye-Din JA, Stewart JA, Dromey JA, Beissbarth T, van Heel DA, Tatham A, Henderson K, Mannering SI, Gianfrani C, Jewell DP, Hill AV, McCluskey J, Rossjohn J, Anderson RP. Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease. Science Translational Medicine. 2: 41ra51. PMID 20650871 DOI: 10.1126/Scitranslmed.3001012  0.397
2010 Godfrey DI, Rossjohn J, McCluskey J. Fighting infection with your MAITs. Nature Immunology. 11: 693-5. PMID 20644577 DOI: 10.1038/Ni0810-693  0.38
2010 Gras S, Chen Z, Miles JJ, Liu YC, Bell MJ, Sullivan LC, Kjer-Nielsen L, Brennan RM, Burrows JM, Neller MA, Khanna R, Purcell AW, Brooks AG, McCluskey J, Rossjohn J, et al. Allelic polymorphism in the T cell receptor and its impact on immune responses. The Journal of Experimental Medicine. 207: 1555-67. PMID 20566715 DOI: 10.1084/Jem.20100603  0.393
2010 Burrows SR, Chen Z, Archbold JK, Tynan FE, Beddoe T, Kjer-Nielsen L, Miles JJ, Khanna R, Moss DJ, Liu YC, Gras S, Kostenko L, Brennan RM, Clements CS, Brooks AG, ... McCluskey J, et al. Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability. Proceedings of the National Academy of Sciences of the United States of America. 107: 10608-13. PMID 20483993 DOI: 10.1073/Pnas.1004926107  0.392
2010 Theodossis A, Guillonneau C, Welland A, Ely LK, Clements CS, Williamson NA, Webb AI, Wilce JA, Mulder RJ, Dunstone MA, Doherty PC, McCluskey J, Purcell AW, Turner SJ, Rossjohn J. Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition. Proceedings of the National Academy of Sciences of the United States of America. 107: 5534-9. PMID 20212169 DOI: 10.1073/Pnas.1000032107  0.344
2010 Crane JS, McCluskey JD, Johnson GT, Harbison RD. Assessment of community healthcare providers ability and willingness to respond to emergencies resulting from bioterrorist attacks. Journal of Emergencies, Trauma, and Shock. 3: 13-20. PMID 20165716 DOI: 10.4103/0974-2700.55808  0.698
2010 Walpole NG, Kjer-Nielsen L, Kostenko L, McCluskey J, Brooks AG, Rossjohn J, Clements CS. The structure and stability of the monomorphic HLA-G are influenced by the nature of the bound peptide. Journal of Molecular Biology. 397: 467-80. PMID 20122941 DOI: 10.1016/J.Jmb.2010.01.052  0.339
2010 Keech CL, Pang KC, McCluskey J, Chen W. Direct antigen presentation by DC shapes the functional CD8(+) T-cell repertoire against the nuclear self-antigen La-SSB. European Journal of Immunology. 40: 330-8. PMID 19950171 DOI: 10.1002/Eji.200939522  0.375
2010 Godfrey DI, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Rossjohn J. Antigen recognition by CD1d-restricted NKT T cell receptors. Seminars in Immunology. 22: 61-7. PMID 19945889 DOI: 10.1016/J.Smim.2009.10.004  0.411
2010 Gras S, Chen Z, Miles JJ, Liu YC, Kjer-Nielsen L, McCluskey J, Burrows SR, Rossjohn J. Structural investigation of T cell tolerance Acta Crystallographica Section A. 66: 33-33. DOI: 10.1107/S0108767310099265  0.329
2009 Macdonald WA, Chen Z, Gras S, Archbold JK, Tynan FE, Clements CS, Bharadwaj M, Kjer-Nielsen L, Saunders PM, Wilce MC, Crawford F, Stadinsky B, Jackson D, Brooks AG, Purcell AW, ... McCluskey J, et al. T cell allorecognition via molecular mimicry. Immunity. 31: 897-908. PMID 20064448 DOI: 10.1016/J.Immuni.2009.09.025  0.392
2009 Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, et al. Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. The Embo Journal. 28: 3781. PMID 19953109 DOI: 10.1038/Emboj.2009.348  0.319
2009 Johnson GT, Harbison SC, McCluskey JD, Harbison RD. Characterization of cancer risk from airborne benzene exposure. Regulatory Toxicology and Pharmacology : Rtp. 55: 361-6. PMID 19703507 DOI: 10.1016/J.Yrtph.2009.08.008  0.71
2009 de Kauwe AL, Chen Z, Anderson RP, Keech CL, Price JD, Wijburg O, Jackson DC, Ladhams J, Allison J, McCluskey J. Resistance to celiac disease in humanized HLA-DR3-DQ2-transgenic mice expressing specific anti-gliadin CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 7440-50. PMID 19494267 DOI: 10.4049/Jimmunol.0900233  0.369
2009 Beddoe T, Chen Z, Clements CS, Ely LK, Bushell SR, Vivian JP, Kjer-Nielsen L, Pang SS, Dunstone MA, Liu YC, Macdonald WA, Perugini MA, Wilce MC, Burrows SR, Purcell AW, ... McCluskey J, et al. Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor. Immunity. 30: 777-88. PMID 19464197 DOI: 10.1016/J.Immuni.2009.03.018  0.392
2009 Bharadwaj M, Thammanichanond D, Aitken CK, Moneer S, Drummer HE, Tracy S, Holdsworth R, Bowden S, Jackson D, Hellard M, Torresi J, McCluskey J. TCD8 response in diverse outcomes of recurrent exposure to hepatitis C virus. Immunology and Cell Biology. 87: 464-72. PMID 19434069 DOI: 10.1038/Icb.2009.24  0.305
2009 Gras S, Burrows SR, Kjer-Nielsen L, Clements CS, Liu YC, Sullivan LC, Bell MJ, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. The shaping of T cell receptor recognition by self-tolerance. Immunity. 30: 193-203. PMID 19167249 DOI: 10.1016/J.Immuni.2008.11.011  0.357
2009 Bell MJ, Burrows JM, Brennan R, Miles JJ, Tellam J, McCluskey J, Rossjohn J, Khanna R, Burrows SR. The peptide length specificity of some HLA class I alleles is very broad and includes peptides of up to 25 amino acids in length. Molecular Immunology. 46: 1911-7. PMID 19157553 DOI: 10.1016/J.Molimm.2008.12.003  0.375
2009 Archbold JK, Macdonald WA, Gras S, Ely LK, Miles JJ, Bell MJ, Brennan RM, Beddoe T, Wilce MC, Clements CS, Purcell AW, McCluskey J, Burrows SR, Rossjohn J. Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition. The Journal of Experimental Medicine. 206: 209-19. PMID 19139173 DOI: 10.1084/Jem.20082136  0.398
2009 Keech CL, Dromey J, Chen Z, Anderson RP, McCluskey J. 355 Immune Tolerance Induced By Peptide Immunotherapy in An HLA Dq2-Dependent Mouse Model of Gluten Immunity Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60258-4  0.378
2008 Scharf JE, Johnson GT, Harbison SC, McCluskey JD, Harbison RD. Dermal absorption of a dilute aqueous solution of malathion. Journal of Emergencies, Trauma, and Shock. 1: 70-3. PMID 19561983 DOI: 10.4103/0974-2700.43182  0.705
2008 Ely LK, Burrows SR, Purcell AW, Rossjohn J, McCluskey J. T-cells behaving badly: structural insights into alloreactivity and autoimmunity. Current Opinion in Immunology. 20: 575-80. PMID 18678247 DOI: 10.1016/J.Coi.2008.07.006  0.381
2008 Chessman D, Kostenko L, Lethborg T, Purcell AW, Williamson NA, Chen Z, Kjer-Nielsen L, Mifsud NA, Tait BD, Holdsworth R, Almeida CA, Nolan D, Macdonald WA, Archbold JK, Kellerher AD, ... ... McCluskey J, et al. Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity. Immunity. 28: 822-32. PMID 18549801 DOI: 10.1016/J.Immuni.2008.04.020  0.375
2008 Archbold JK, Macdonald WA, Burrows SR, Rossjohn J, McCluskey J. T-cell allorecognition: a case of mistaken identity or déjà vu? Trends in Immunology. 29: 220-6. PMID 18378495 DOI: 10.1016/J.It.2008.02.005  0.385
2008 Godfrey DI, Rossjohn J, McCluskey J. The fidelity, occasional promiscuity, and versatility of T cell receptor recognition. Immunity. 28: 304-14. PMID 18342005 DOI: 10.1016/J.Immuni.2008.02.004  0.391
2008 Wynn KK, Fulton Z, Cooper L, Silins SL, Gras S, Archbold JK, Tynan FE, Miles JJ, McCluskey J, Burrows SR, Rossjohn J, Khanna R. Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection. Blood. 111: 4283-92. PMID 18270323 DOI: 10.1182/Blood-2007-11-122622  0.422
2008 Unanue ER, McCluskey J. Dressing for the occasion: APCs make antigens presentable. Current Opinion in Immunology. 20: 49-51. PMID 18249104 DOI: 10.1016/J.Coi.2007.12.003  0.31
2008 Gras S, Kjer-Nielsen L, Burrows SR, McCluskey J, Rossjohn J. T-cell receptor bias and immunity. Current Opinion in Immunology. 20: 119-25. PMID 18207719 DOI: 10.1016/J.Coi.2007.12.001  0.386
2008 Mifsud NA, Purcell AW, Chen W, Holdsworth R, Tait BD, McCluskey J. Immunodominance hierarchies and gender bias in direct T(CD8)-cell alloreactivity. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 8: 121-32. PMID 18093278 DOI: 10.1111/J.1600-6143.2007.02044.X  0.393
2008 Archbold JK, Ely LK, Kjer-Nielsen L, Burrows SR, Rossjohn J, McCluskey J, Macdonald WA. T cell allorecognition and MHC restriction--A case of Jekyll and Hyde? Molecular Immunology. 45: 583-98. PMID 17869342 DOI: 10.1016/J.Molimm.2006.05.018  0.386
2008 Garlepp MJ, Chen W, Tabarias H, Baines M, Brooks A, McCLUSKEY J. Antigen processing and presentation by a murine myoblast cell line Clinical and Experimental Immunology. 102: 614-619. PMID 8536381 DOI: 10.1111/J.1365-2249.1995.Tb03861.X  0.344
2008 Rischmueller M, McNeilage LJ, McCluskey J, Gordon T. Human autoantibodies directed against the RNA recognition motif of La (SS-B) bind to a conformational epitope present on the intact La (SS-B)/Ro (SS-A) ribonucleoprotein particle Clinical and Experimental Immunology. 101: 39-44. PMID 7542577 DOI: 10.1111/J.1365-2249.1995.Tb02274.X  0.312
2008 Gras S, Kjer-Nielsen L, Clements CS, Burrows SR, McCluskey J, Rossjohn J. Structure of the subdominant TCR in complex with HLA-B8FLRGRAYGL Acta Crystallographica Section A. 64: 316-316. DOI: 10.1107/S0108767308089903  0.301
2008 Chessman D, Kostenko L, Lethborg T, Purcell AW, Williamson NA, Chen Z, Kjer-Nielsen L, Mifsud NA, Tait BD, Holdsworth R, Almeida CA, Nolan D, Macdonald WA, Archbold JK, Kellerher AD, ... ... McCluskey J, et al. Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity (DOI: 10.1016/j.immuni.2008.04.020) Immunity. 29. DOI: 10.1016/J.Immuni.2008.06.002  0.352
2007 Henderson KN, Reid HH, Borg NA, Broughton SE, Huyton T, Anderson RP, McCluskey J, Rossjohn J. The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 1021-5. PMID 18084083 DOI: 10.1107/S1744309107051408  0.362
2007 Dudek NL, Maier S, Chen ZJ, Mudd PA, Mannering SI, Jackson DC, Zeng W, Keech CL, Hamlin K, Pan ZJ, Davis-Schwarz K, Workman-Azbill J, Bachmann M, McCluskey J, Farris AD. T cell epitopes of the La/SSB autoantigen in humanized transgenic mice expressing the HLA class II haplotype DRB1*0301/DQB1*0201. Arthritis and Rheumatism. 56: 3387-98. PMID 17907193 DOI: 10.1002/Art.22870  0.415
2007 Henderson KN, Tye-Din JA, Reid HH, Chen Z, Borg NA, Beissbarth T, Tatham A, Mannering SI, Purcell AW, Dudek NL, van Heel DA, McCluskey J, Rossjohn J, Anderson RP. A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease. Immunity. 27: 23-34. PMID 17629515 DOI: 10.1016/J.Immuni.2007.05.015  0.344
2007 Borg N, Wun KS, Kjer-Nielsen L, Wilce MCJ, Pellicci DG, Koh R, Besra GS, Bharadwaj M, Godfrey DI, McCluskey J, Rossjohn J. CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor Nature. 448: 44-49. PMID 17581592 DOI: 10.1038/Nature05907  0.403
2007 Martin AM, Almeida CA, Cameron P, Purcell AW, Nolan D, James I, McCluskey J, Phillips E, Landay A, Mallal S. Immune responses to abacavir in antigen-presenting cells from hypersensitive patients. Aids (London, England). 21: 1233-44. PMID 17545699 DOI: 10.1097/Qad.0B013E3280119579  0.355
2007 Rossjohn J, McCluskey J. How a Home-Grown T Cell Receptor Interacts with a Foreign Landscape Cell. 129: 19-20. PMID 17418777 DOI: 10.1016/J.Cell.2007.03.018  0.354
2007 Clements CS, Kjer-Nielsen L, McCluskey J, Rossjohn J. Structural studies on HLA-G: implications for ligand and receptor binding. Human Immunology. 68: 220-226. PMID 17400055 DOI: 10.1016/J.Humimm.2006.09.003  0.328
2007 Burrows JM, Wynn KK, Tynan FE, Archbold J, Miles JJ, Bell MJ, Brennan RM, Walker S, McCluskey J, Rossjohn J, Khanna R, Burrows SR. The impact of HLA-B micropolymorphism outside primary peptide anchor pockets on the CTL response to CMV. European Journal of Immunology. 37: 946-53. PMID 17357107 DOI: 10.1002/Eji.200636588  0.372
2007 Tynan FE, Reid HH, Kjer-Nielsen L, Miles JJ, Wilce MC, Kostenko L, Borg NA, Williamson NA, Beddoe T, Purcell AW, Burrows SR, McCluskey J, Rossjohn J. A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule. Nature Immunology. 8: 268-76. PMID 17259989 DOI: 10.1038/Ni1432  0.407
2006 Turner SJ, Doherty PC, McCluskey J, Rossjohn J. Structural determinants of T-cell receptor bias in immunity. Nature Reviews. Immunology. 6: 883-94. PMID 17110956 DOI: 10.1038/Nri1977  0.375
2006 Miles JJ, Borg NA, Brennan RM, Tynan FE, Kjer-Nielsen L, Silins SL, Bell MJ, Burrows JM, McCluskey J, Rossjohn J, Burrows SR. TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope. Journal of Immunology (Baltimore, Md. : 1950). 177: 6804-14. PMID 17082594 DOI: 10.4049/Jimmunol.177.10.6804  0.364
2006 Clements CS, Dunstone MA, Macdonald WA, McCluskey J, Rossjohn J. Specificity on a knife-edge: the αβ T cell receptor Current Opinion in Structural Biology. 16: 787-795. PMID 17011774 DOI: 10.1016/J.Sbi.2006.09.004  0.381
2006 Archbold JK, Macdonald WA, Miles JJ, Brennan RM, Kjer-Nielsen L, McCluskey J, Burrows SR, Rossjohn J. Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry. The Journal of Biological Chemistry. 281: 34324-32. PMID 16963442 DOI: 10.1074/Jbc.M606755200  0.408
2006 Chen Z, de Kauwe AL, Keech C, Wijburg O, Simpfendorfer K, Alexander WS, McCluskey J. Humanized transgenic mice expressing HLA DR4-DQ3 haplotype: reconstitution of phenotype and HLA-restricted T-cell responses. Tissue Antigens. 68: 210-9. PMID 16948641 DOI: 10.1111/J.1399-0039.2006.00656.X  0.389
2006 Chen W, McCluskey J. Immunodominance and Immunodomination: Critical Factors in Developing Effective CD8+ T-Cell-Based Cancer Vaccines Advances in Cancer Research. 95: 203-247. PMID 16860659 DOI: 10.1016/S0065-230X(06)95006-4  0.358
2006 Sullivan LC, Hoare HL, McCluskey J, Rossjohn J, Brooks AG. A structural perspective on MHC class Ib molecules in adaptive immunity Trends in Immunology. 27: 413-420. PMID 16860610 DOI: 10.1016/J.It.2006.07.006  0.332
2006 Ely LK, Beddoe T, Clements CS, Matthews JM, Purcell AW, Kjer-Nielsen L, McCluskey J, Rossjohn J. Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction. Proceedings of the National Academy of Sciences of the United States of America. 103: 6641-6. PMID 16617112 DOI: 10.1073/Pnas.0600743103  0.351
2006 Clements CS, Kjer-Nielsen L, Kostenko L, McCluskey J, Rossjohn J. The production, purification and crystallization of a soluble form of the nonclassical MHC HLA-G: the essential role of cobalt Acta Crystallographica Section F-Structural Biology and Crystallization Communications. 62: 70-73. PMID 16511266 DOI: 10.1107/S1744309105041473  0.317
2006 Kjer-Nielsen L, Borg NA, Pellicci DG, Beddoe TC, Kostenko L, Clements CS, Williamson NA, Smyth MJ, Besra GS, Reid HH, Bharadwaj M, Godfrey DI, Rossjohn J, McCluskey J. A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition Journal of Experimental Medicine. 203: 661-673. PMID 16505140 DOI: 10.1084/Jem.20051777  0.38
2006 Hoare HL, Sullivan LC, Pietra G, Clements CS, Lee EJ, Ely LK, Beddoe TC, Falco M, Kjer-Nielsen L, Reid HH, McCluskey J, Moretta L, Rossjohn J, Brooks AG. Structural basis for a major histocompatibility complex class Ib–restricted T cell response Nature Immunology. 7: 256-264. PMID 16474394 DOI: 10.1038/Ni1312  0.366
2006 Pan ZJ, Davis K, Maier S, Bachmann MP, Kim-Howard XR, Keech C, Gordon TP, McCluskey J, Farris AD. Neo-epitopes are required for immunogenicity of the La/SS-B nuclear antigen in the context of late apoptotic cells. Clinical and Experimental Immunology. 143: 237-48. PMID 16412047 DOI: 10.1111/J.1365-2249.2005.03001.X  0.381
2006 Burrows SR, Rossjohn J, McCluskey J. Have we cut ourselves too short in mapping CTL epitopes Trends in Immunology. 27: 11-16. PMID 16297661 DOI: 10.1016/J.It.2005.11.001  0.333
2005 Tynan FE, Elhassen D, Purcell AW, Burrows JM, Borg NA, Miles JJ, Williamson NA, Green KJ, Tellam J, Kjer-Nielsen L, McCluskey J, Rossjohn J, Burrows SR. The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation. The Journal of Experimental Medicine. 202: 1249-60. PMID 16275762 DOI: 10.1084/Jem.20050864  0.403
2005 Tynan FE, Burrows SR, Buckle AM, Clements CS, Borg NA, Miles JJ, Beddoe T, Whisstock JC, Wilce MC, Silins SL, Burrows JM, Kjer-Nielsen L, Kostenko L, Purcell AW, McCluskey J, et al. T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide. Nature Immunology. 6: 1114-22. PMID 16186824 DOI: 10.1038/Ni1257  0.382
2005 Miles JJ, Elhassen D, Borg NA, Silins SL, Tynan FE, Burrows JM, Purcell AW, Kjer-Nielsen L, Rossjohn J, Burrows SR, McCluskey J. CTL recognition of a bulged viral peptide involves biased TCR selection. Journal of Immunology (Baltimore, Md. : 1950). 175: 3826-34. PMID 16148129 DOI: 10.4049/Jimmunol.175.6.3826  0.35
2005 Webb AI, Dunstone MA, Williamson NA, Price JD, de Kauwe A, Chen W, Oakley A, Perlmutter P, McCluskey J, Aguilar MI, Rossjohn J, Purcell AW. T cell determinants incorporating beta-amino acid residues are protease resistant and remain immunogenic in vivo. Journal of Immunology (Baltimore, Md. : 1950). 175: 3810-8. PMID 16148127 DOI: 10.4049/Jimmunol.175.6.3810  0.319
2005 Ely LK, Kjer-Nielsen L, McCluskey J, Rossjohn J. Structural Studies on the αβ T‐cell Receptor Iubmb Life. 57: 575-582. PMID 16118115 DOI: 10.1080/15216540500215556  0.383
2005 Godfrey DI, McCluskey J, Rossjohn J. CD1d antigen presentation: treats for NKT cells Nature Immunology. 6: 754-756. PMID 16034430 DOI: 10.1038/Ni0805-754  0.313
2005 Sesma L, Galocha B, Vázquez M, Purcell AW, Marcilla M, McCluskey J, López de Castro JA. Qualitative and quantitative differences in peptides bound to HLA-B27 in the presence of mouse versus human tapasin define a role for tapasin as a size-dependent peptide editor. Journal of Immunology (Baltimore, Md. : 1950). 174: 7833-44. PMID 15944288 DOI: 10.4049/Jimmunol.174.12.7833  0.329
2005 Stratov I, Dale CJ, Chea S, McCluskey J, Kent SJ. Induction of T-cell immunity to antiretroviral drug-resistant human immunodeficiency virus type 1. Journal of Virology. 79: 7728-37. PMID 15919925 DOI: 10.1128/Jvi.79.12.7728-7737.2005  0.321
2005 Tynan FE, Borg NA, Miles JJ, Beddoe T, El-Hassen D, Silins SL, van Zuylen WJ, Purcell AW, Kjer-Nielsen L, McCluskey J, Burrows SR, Rossjohn J. High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance. The Journal of Biological Chemistry. 280: 23900-9. PMID 15849183 DOI: 10.1074/Jbc.M503060200  0.423
2005 Ely LK, Green KJ, Beddoe T, Clements CS, Miles JJ, Bottomley SP, Zernich D, Kjer-Nielsen L, Purcell AW, McCluskey J, Rossjohn J, Burrows SR. Antagonism of antiviral and allogeneic activity of a human public CTL clonotype by a single altered peptide ligand: implications for allograft rejection. Journal of Immunology (Baltimore, Md. : 1950). 174: 5593-601. PMID 15843558 DOI: 10.4049/Jimmunol.174.9.5593  0.392
2005 Turner SJ, Kedzierska K, Komodromou H, La Gruta NL, Dunstone MA, Webb AI, Webby R, Walden H, Xie W, McCluskey J, Purcell AW, Rossjohn J, Doherty PC. Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations. Nature Immunology. 6: 382-9. PMID 15735650 DOI: 10.1038/Ni1175  0.359
2005 Clements CS, Kjer-Nielsen L, Kostenko L, Hoare HL, Dunstone MA, Moses E, Freed K, Brooks AG, Rossjohn J, McCluskey J. Crystal structure of HLA-G: a nonclassical MHC class I molecule expressed at the fetal-maternal interface. Proceedings of the National Academy of Sciences of the United States of America. 102: 3360-5. PMID 15718280 DOI: 10.1073/Pnas.0409676102  0.348
2005 Borg NA, Ely LK, Beddoe T, Macdonald WA, Reid HH, Clements CS, Purcell AW, Kjer-Nielsen L, Miles JJ, Burrows SR, McCluskey J, Rossjohn J. The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition. Nature Immunology. 6: 171-80. PMID 15640805 DOI: 10.1038/Ni1155  0.368
2004 McCluskey J, Rossjohn J, Purcell AW. TAP genes and immunity. Current Opinion in Immunology. 16: 651-9. PMID 15342013 DOI: 10.1016/J.Coi.2004.07.016  0.331
2004 Dunstone MA, Kjer-Nielsen L, Kostenko L, Purcell AW, Brooks AG, Rossjohn J, McCluskey J. The production and purification of the human T-cell receptors, the CD3epsilongamma and CD3epsilondelta heterodimers: complex formation and crystallization with OKT3, a therapeutic monoclonal antibody. Acta Crystallographica. Section D, Biological Crystallography. 60: 1425-8. PMID 15272166 DOI: 10.1107/S0907444904012041  0.314
2004 Zernich D, Purcell AW, Macdonald WA, Kjer-Nielsen L, Ely LK, Laham N, Crockford T, Mifsud NA, Bharadwaj M, Chang L, Tait BD, Holdsworth R, Brooks AG, Bottomley SP, Beddoe T, ... ... McCluskey J, et al. Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion. The Journal of Experimental Medicine. 200: 13-24. PMID 15226359 DOI: 10.1084/Jem.20031680  0.351
2004 Webb AI, Borg NA, Dunstone MA, Kjer-Nielsen L, Beddoe T, McCluskey J, Carbone FR, Bottomley SP, Aguilar MI, Purcell AW, Rossjohn J. The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance. Journal of Immunology (Baltimore, Md. : 1950). 173: 402-9. PMID 15210799 DOI: 10.4049/Jimmunol.173.1.402  0.36
2004 Chen Q, Jackson H, Parente P, Luke T, Rizkalla M, Tai TY, Zhu HC, Mifsud NA, Dimopoulos N, Masterman KA, Hopkins W, Goldie H, Maraskovsky E, Green S, Miloradovic L, ... McCluskey J, et al. Immunodominant CD4+ responses identified in a patient vaccinated with full-length NY-ESO-1 formulated with ISCOMATRIX adjuvant. Proceedings of the National Academy of Sciences of the United States of America. 101: 9363-8. PMID 15197261 DOI: 10.1073/Pnas.0403271101  0.355
2004 Kjer-Nielsen L, Dunstone MA, Kostenko L, Ely LK, Beddoe T, Mifsud NA, Purcell AW, Brooks AG, McCluskey J, Rossjohn J. Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3. Proceedings of the National Academy of Sciences of the United States of America. 101: 7675-80. PMID 15136729 DOI: 10.1073/Pnas.0402295101  0.373
2004 Martin AM, Nolan D, Gaudieri S, Almeida CA, Nolan R, James I, Carvalho F, Phillips E, Christiansen FT, Purcell AW, McCluskey J, Mallal S. Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proceedings of the National Academy of Sciences of the United States of America. 101: 4180-5. PMID 15024131 DOI: 10.1073/Pnas.0307067101  0.344
2004 Webb AI, Dunstone MA, Chen W, Aguilar MI, Chen Q, Jackson H, Chang L, Kjer-Nielsen L, Beddoe T, McCluskey J, Rossjohn J, Purcell AW. Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue. The Journal of Biological Chemistry. 279: 23438-46. PMID 15004033 DOI: 10.1074/Jbc.M314066200  0.346
2003 McCluskey J, Kanaan C, Diviney M. Nomenclature and serology of HLA class I and class II alleles. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Appendix 1S. PMID 18432895 DOI: 10.1002/0471142735.Ima01S52  0.364
2003 Aplin BD, Keech CL, de Kauwe AL, Gordon TP, Cavill D, McCluskey J. Tolerance through indifference: autoreactive B cells to the nuclear antigen La show no evidence of tolerance in a transgenic model. Journal of Immunology (Baltimore, Md. : 1950). 171: 5890-900. PMID 14634099 DOI: 10.4049/Jimmunol.171.11.5890  0.36
2003 Chang L, Kjer-Nielsen L, Flynn S, Brooks AG, Mannering SI, Honeyman MC, Harrison LC, McCluskey J, Purcell AW. Novel strategy for identification of candidate cytotoxic T-cell epitopes from human preproinsulin. Tissue Antigens. 62: 408-17. PMID 14617048 DOI: 10.1034/J.1399-0039.2003.00122.X  0.365
2003 Macdonald WA, Purcell AW, Mifsud NA, Ely LK, Williams DS, Chang L, Gorman JJ, Clements CS, Kjer-Nielsen L, Koelle DM, Burrows SR, Tait BD, Holdsworth R, Brooks AG, Lovrecz GO, ... ... McCluskey J, et al. A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition. The Journal of Experimental Medicine. 198: 679-91. PMID 12939341 DOI: 10.1084/Jem.20030066  0.353
2003 Mannering SI, Purcell AW, Honeyman MC, McCluskey J, Harrison LC. Human T-cells recognise N-terminally Fmoc-modified peptide. Vaccine. 21: 3638-46. PMID 12922093 DOI: 10.1016/S0264-410X(03)00402-X  0.345
2003 Kjer-Nielsen L, Clements CS, Purcell AW, Brooks AG, Whisstock JC, Burrows SR, McCluskey J, Rossjohn J. A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity. Immunity. 18: 53-64. PMID 12530975 DOI: 10.1016/S1074-7613(02)00513-7  0.373
2002 Clements CS, Kjer-Nielsen L, MacDonald WA, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state. Acta Crystallographica. Section D, Biological Crystallography. 58: 2131-4. PMID 12454477 DOI: 10.1107/S0907444902015482  0.389
2002 Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance. Structure (London, England : 1993). 10: 1521-32. PMID 12429093 DOI: 10.1016/S0969-2126(02)00878-X  0.393
2002 Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, Fontes MR, McCluskey J, Rossjohn J. The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization. Journal of Immunology (Baltimore, Md. : 1950). 169: 5153-60. PMID 12391232 DOI: 10.4049/Jimmunol.169.9.5153  0.366
2002 Macdonald W, Williams DS, Clements CS, Gorman JJ, Kjer-Nielsen L, Brooks AG, McCluskey J, Rossjohn J, Purcell AW. Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex. Febs Letters. 527: 27-32. PMID 12220628 DOI: 10.1016/S0014-5793(02)03149-6  0.344
2002 Gordon TP, Kinoshita G, Cavill D, Keech C, Farris A, Kaufman K, McCluskey J, Purcell A. Restricted specificity of intermolecular spreading to endogenous La (SS-B) and 60 kDa Ro (SS-A) in experimental autoimmunity. Scandinavian Journal of Immunology. 56: 168-73. PMID 12121436 DOI: 10.1046/J.1365-3083.2002.01115.X  0.318
2002 Williams AP, Peh CA, Purcell AW, McCluskey J, Elliott T. Optimization of the MHC class I peptide cargo is dependent on tapasin. Immunity. 16: 509-20. PMID 11970875 DOI: 10.1016/S1074-7613(02)00304-7  0.309
2002 Chen Z, Dudek N, Wijburg O, Strugnell R, Brown L, Deliyannis G, Jackson D, Koentgen F, Gordon T, McCluskey J. A 320-Kilobase Artificial Chromosome Encoding the Human HLA DR3-DQ2 MHC Haplotype Confers HLA Restriction in Transgenic Mice Journal of Immunology. 168: 3050-3056. PMID 11884478 DOI: 10.4049/Jimmunol.168.6.3050  0.391
2001 Keech CL, Farris AD, Beroukas D, Gordon TP, McCluskey J. Cognate T cell help is sufficient to trigger anti-nuclear autoantibodies in naive mice. Journal of Immunology (Baltimore, Md. : 1950). 166: 5826-34. PMID 11313427 DOI: 10.4049/Jimmunol.166.9.5826  0.363
2001 Purcell AW, Gorman JJ, Garcia-Peydró M, Paradela A, Burrows SR, Talbo GH, Laham N, Peh CA, Reynolds EC, López De Castro JA, McCluskey J. Quantitative and qualitative influences of tapasin on the class I peptide repertoire. Journal of Immunology (Baltimore, Md. : 1950). 166: 1016-27. PMID 11145681 DOI: 10.4049/Jimmunol.166.2.1016  0.346
2001 Harbison RD, McCluskey J. Evaluating occupational claims of chemical-induced injury Chemical Health and Safety. 8: 6-9. DOI: 10.1016/S1074-9098(01)00211-8  0.515
2000 Farris AD, Keech CL, Gordon TP, McCluskey J. Epitope mimics and determinant spreading: pathways to autoimmunity. Cellular and Molecular Life Sciences : Cmls. 57: 569-78. PMID 11130457 DOI: 10.1007/Pl00000719  0.307
2000 Barnden MJ, Purcell AW, Gorman JJ, McCluskey J. Tapasin-mediated retention and optimization of peptide ligands during the assembly of class I molecules. Journal of Immunology (Baltimore, Md. : 1950). 165: 322-30. PMID 10861068 DOI: 10.4049/Jimmunol.165.1.322  0.334
2000 McColl GJ, Diviney MB, Holdsworth RF, McNair PD, Carnie J, Hart W, McCluskey J. HLA-B27 expression and reactive arthritis susceptibility in two patient cohorts infected with Salmonella typhimurium Australian and New Zealand Journal of Medicine. 30: 28-32. PMID 10800874 DOI: 10.1111/J.1445-5994.2000.Tb01050.X  0.303
2000 Purcell AW, Kelly AJ, Peh CA, Dudek NL, McCluskey J. Endogenous and exogenous factors contributing to the surface expression of HLA B27 on mutant APC. Human Immunology. 61: 120-30. PMID 10717804 DOI: 10.1016/S0198-8859(99)00139-1  0.343
2000 Peh CA, Laham N, Burrows SR, Zhu Y, McCluskey J. Distinct Functions of Tapasin Revealed by Polymorphism in MHC Class I Peptide Loading Journal of Immunology. 164: 292-299. PMID 10605023 DOI: 10.4049/Jimmunol.164.1.292  0.348
1998 McCluskey J, Farris AD, Keech CL, Purcell AW, Rischmueller M, Kinoshita G, Reynolds P, Gordon TP. Determinant spreading: lessons from animal models and human disease. Immunological Reviews. 164: 209-29. PMID 9795778 DOI: 10.1111/J.1600-065X.1998.Tb01222.X  0.354
1998 Peh CA, Burrows SR, Barnden M, Khanna R, Cresswell P, Moss DJ, McCluskey J. HLA-B27-restricted antigen presentation in the absence of tapasin reveals polymorphism in mechanisms of HLA class I peptide loading. Immunity. 8: 531-42. PMID 9620674 DOI: 10.1016/S1074-7613(00)80558-0  0.358
1998 Rischmueller M, Lester S, Chen Z, Champion G, Van Den Berg R, Beer R, Coates T, McCluskey J, Gordon T. HLA class II phenotype controls diversification of the autoantibody response in primary Sjögren's syndrome (pSS). Clinical and Experimental Immunology. 111: 365-71. PMID 9486405 DOI: 10.1046/J.1365-2249.1998.00504.X  0.351
1997 Burrows SR, Silins SL, Khanna R, Burrows JM, Rischmueller M, McCluskey J, Moss DJ. Cross‐reactive memory T cells for Epstein‐Barr virus augment the alloresponse to common human leukocyte antigens: degenerate recognition of major histocompatibility complex‐bound peptide by T cells and its role in alloreactivity European Journal of Immunology. 27: 1726-1736. PMID 9247584 DOI: 10.1002/Eji.1830270720  0.412
1997 Weenink S, Averdunk H, Boston T, Boswarva V, Guery J, Adorini L, Mellins E, McCluskey J, Gautam AM. Impaired antigen presentation by murine I-Ad class II MHC molecules expressed in normal and HLA-DM-defective human B cell lines. International Immunology. 9: 889-896. PMID 9199972 DOI: 10.1093/Intimm/9.6.889  0.391
1997 Burrows SR, Silins SL, Cross SM, Peh CA, Rischmueller M, Burrows JM, Elliott SL, McCluskey J. Human leukocyte antigen phenotype imposes complex constraints on the antigen-specific cytotoxic T lymphocyte repertoire. European Journal of Immunology. 27: 178-82. PMID 9022015 DOI: 10.1002/Eji.1830270126  0.394
1996 Reynolds P, Gordon TP, Purcell AW, Jackson DC, McCluskey J. Hierarchical self-tolerance to T cell determinants within the ubiquitous nuclear self-antigen La (SS-B) permits induction of systemic autoimmunity in normal mice. The Journal of Experimental Medicine. 184: 1857-70. PMID 8920873 DOI: 10.1084/Jem.184.5.1857  0.376
1996 Lienert K, Russ G, Lester S, Bennett G, Gao X, McCluskey J. Stable inheritance of an HLA-"blank" phenotype associated with a structural mutation in the HLA-A*0301 gene. Tissue Antigens. 48: 187-191. PMID 8896177 DOI: 10.1111/J.1399-0039.1996.Tb02627.X  0.328
1995 Keech CL, Gordon TP, McCluskey J. Cytoplasmic accumulation of the 52 kDa Ro/SS-A nuclear autoantigen in transfected cell lines. Journal of Autoimmunity. 8: 699-712. PMID 8579725 DOI: 10.1006/Jaut.1995.0052  0.308
1995 Chen W, McCluskey J. Electroporation of antigen-presenting cells for T-cell recognition and cytotoxic T-lymphocyte priming Methods in Molecular Biology (Clifton, N.J.). 48: 73-81. PMID 8528410 DOI: 10.1385/0-89603-304-X:73  0.371
1995 Lienert K, McCluskey J, Bennett G, Fowler C, Russ G. HLA class I variation in Australian Aborigines: characterization of allele B*1521 Tissue Antigens. 45: 12-17. PMID 7725306 DOI: 10.1111/J.1399-0039.1995.Tb02409.X  0.309
1995 Wade WF, Dickman DK, Peterson D, McCluskey J, Khrebtukova I. Class II cytoplasmic and transmembrane domains are not required for class II-mediated B cell spreading. Immunology Letters. 44: 67-74. PMID 7721346 DOI: 10.1016/0165-2478(94)00178-T  0.318
1994 Weisan C, Fecondo J, McCluskey J. The structural influence of individual residues located within peptide antigen depends upon their sequence context Molecular Immunology. 31: 1069-1075. PMID 7935498 DOI: 10.1016/0161-5890(94)90102-3  0.319
1994 Gordon T, Topfer F, Keech C, Reynolds P, Chen W, Rischmueller M, McCluskey J. How Does Autoimmunity to La and Ro Initiate and Spread Autoimmunity. 18: 87-92. PMID 7742478 DOI: 10.3109/08916939409007981  0.366
1994 Chen W, Khilko S, Fecondo J, Margulies DH, McCluskey J. Determinant selection of major histocompatibility complex class I-restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues. Journal of Experimental Medicine. 180: 1471-1483. PMID 7523572 DOI: 10.1084/Jem.180.4.1471  0.339
1994 Kanost D, McCluskey J. Anergic B cells constitutively present self antigen: Enhanced immunoglobulin receptor-mediated presentation of antigenic determinants by B cells is hierarchical European Journal of Immunology. 24: 1186-1193. PMID 7514133 DOI: 10.1002/Eji.1830240527  0.336
1993 Chen W, Mccluskey J, Rodda S, Carbone FR. Changes at peptide residues buried in the major histocompatibility complex (MHC) class I binding cleft influence T cell recognition: a possible role for indirect conformational alterations in the MHC class I or bound peptide in determining T cell recognition. Journal of Experimental Medicine. 177: 869-873. PMID 8436915 DOI: 10.1084/Jem.177.3.869  0.379
1993 Kanost D, Basten A, McCluskey J. Threshold detection of self-antigen/MHC class II complexes formed in vivo: constitutive presentation of an immunodominant epitope of hen egg lysozyme (HEL) in HEL-transgenic mice. International Immunology. 5: 893-902. PMID 8398984 DOI: 10.1093/Intimm/5.8.893  0.348
1993 Keech CL, Gordon TP, Reynolds P, McCluskey J. Expression and functional conservation of the human La (SS-B) nuclear autoantigen in murine cell lines. Journal of Autoimmunity. 6: 543-55. PMID 8240660 DOI: 10.1006/Jaut.1993.1045  0.318
1993 Weng YM, McNeilage J, Topfer F, McCluskey J, Gordon T. Identification of a human-specific epitope in a conserved region of the La/SS-B autoantigen. Journal of Clinical Investigation. 92: 1104-1108. PMID 7688758 DOI: 10.1172/Jci116617  0.302
1993 Chen W, Carbone FR, McCluskey J. Electroporation and commercial liposomes efficiently deliver soluble protein into the MHC class I presentation pathway: Priming in vitro and in vivo for class I-restricted recognition of soluble antigen Journal of Immunological Methods. 160: 49-57. PMID 7680698 DOI: 10.1016/0022-1759(93)90007-T  0.401
1992 Blok R, Margulies DH, Pease L, Ribaudo RK, Schneck JP, Mccluskey J. CD8 expression alters the fine specificity of an alloreactive MHC class I-specific T hybridoma International Immunology. 4: 455-466. PMID 1591216 DOI: 10.1093/Intimm/4.4.455  0.331
1991 Dietzsch E, Hong J, Leslie DE, Martin L, Rolland J, Benson E, Toh BH, McCluskey J. T cell receptor and immunoglobulin gene rearrangement analysis as a laboratory aid in the diagnosis of human malignant lymphoproliferative diseases Australian and New Zealand Journal of Medicine. 21: 307-313. PMID 1953508 DOI: 10.1111/J.1445-5994.1991.Tb04695.X  0.322
1991 Brooks A, Hartley S, Kjer-Nielsen L, Perera J, Goodnow CC, Basten A, McCluskey J. Class II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozyme. Proceedings of the National Academy of Sciences of the United States of America. 88: 3290-4. PMID 1707537 DOI: 10.1073/Pnas.88.8.3290  0.37
1990 McCluskey J, Kjer-Nielsen L, Blok R. Structure function analysis of in vitro mutated CD4 and major histocompatibility complex class II gene products. Journal of Autoimmunity. 3: 91-96. PMID 2340062 DOI: 10.1016/S0896-8411(09)90016-6  0.317
1985 Golding H, McCluskey J, Munitz TI, Germain RN, Margulies DH, Singer A. T-cell recognition of a chimaeric class II/class I MHC molecule and the role of L3T4. Nature. 317: 425-7. PMID 3930971 DOI: 10.1038/317425A0  0.384
1985 McCluskey J, Germain RN, Margulies DH. Cell surface expression of an in vitro recombinant class II/class I major histocompatibility complex gene product. Cell. 40: 247-57. PMID 2578320 DOI: 10.1016/0092-8674(85)90139-4  0.305
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