Peter A. Jones, PhD - Publications

Affiliations: 
University of Southern California University of Southern California, Los Angeles, CA, United States 
Area:
DNA methylation, cancer, epigenetics

205 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Gillberg L, Ørskov AD, Nasif A, Ohtani H, Madaj Z, Hansen JW, Rapin N, Mogensen JB, Liu M, Dufva IH, Lykkesfeldt J, Hajkova P, Jones PA, Grønbæk K. Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes. Clinical Epigenetics. 11: 143. PMID 31623675 DOI: 10.1186/s13148-019-0739-5  0.6
2019 Jones PA, Ohtani H, Chakravarthy A, De Carvalho DD. Epigenetic therapy in immune-oncology. Nature Reviews. Cancer. PMID 30723290 DOI: 10.1038/s41568-019-0109-9  0.6
2018 Carpenter BL, Zhou W, Madaj Z, DeWitt AK, Ross JP, Grønbæk K, Liang G, Clark SJ, Molloy PL, Jones PA. Mother-child transmission of epigenetic information by tunable polymorphic imprinting. Proceedings of the National Academy of Sciences of the United States of America. PMID 30509985 DOI: 10.1073/pnas.1815005115  0.72
2018 Liu M, Thomas SL, DeWitt AK, Zhou W, Madaj ZB, Ohtani H, Baylin SB, Liang G, Jones PA. Dual inhibition of DNA and histone methyltransferases increases viral mimicry in ovarian cancer cells. Cancer Research. PMID 30185548 DOI: 10.1158/0008-5472.CAN-17-3953  0.72
2018 Ohtani H, Liu M, Zhou W, Liang G, Jones PA. Switching roles for DNA and histone methylation depend on evolutionary ages of human endogenous retroviruses. Genome Research. PMID 29970451 DOI: 10.1101/gr.234229.118  0.72
2018 Lay FD, Kelly TK, Jones PA. Nucleosome Occupancy and Methylome Sequencing (NOMe-seq). Methods in Molecular Biology (Clifton, N.J.). 1708: 267-284. PMID 29224149 DOI: 10.1007/978-1-4939-7481-8_14  0.64
2017 Choi SK, Pandiyan K, Eun JW, Yang X, Hong SH, Nam SW, Jones PA, Liang G, You JS. Epigenetic landscape change analysis during human EMT sheds light on a key EMT mediator TRIM29. Oncotarget. 8: 98322-98335. PMID 29228692 DOI: 10.18632/oncotarget.21681  0.72
2017 Gillberg L, Ørskov AD, Liu M, Harsløf LBS, Jones PA, Grønbæk K. Vitamin C - a new player in regulation of the cancer epigenome. Seminars in Cancer Biology. PMID 29102482 DOI: 10.1016/j.semcancer.2017.11.001  0.6
2017 Lakshminarasimhan R, Andreu-Vieyra C, Lawrenson K, Duymich CE, Gayther SA, Liang G, Jones PA. Down-regulation of ARID1A is sufficient to initiate neoplastic transformation along with epigenetic reprogramming in non-tumorigenic endometriotic cells. Cancer Letters. PMID 28483516 DOI: 10.1016/j.canlet.2017.04.040  0.72
2017 Vincent M, Mundbjerg K, Skou Pedersen J, Liang G, Jones PA, Ørntoft TF, Dalsgaard Sørensen K, Wiuf C. epiG: statistical inference and profiling of DNA methylation from whole-genome bisulfite sequencing data. Genome Biology. 18: 38. PMID 28222791 DOI: 10.1186/s13059-017-1168-4  0.72
2017 Azad NS, El-Khoueiry A, Yin J, Oberg AL, Flynn P, Adkins D, Sharma A, Weisenberger DJ, Brown T, Medvari P, Jones PA, Easwaran H, Kamel I, Bahary N, Kim G, et al. Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat; a phase 2 consortium/stand Up 2 cancer study. Oncotarget. PMID 28186961 DOI: 10.18632/oncotarget.15108  0.6
2017 Helbo AS, Lay FD, Jones PA, Liang G, Grønbæk K. Nucleosome Positioning and NDR Structure at RNA Polymerase III Promoters. Scientific Reports. 7: 41947. PMID 28176797 DOI: 10.1038/srep41947  0.72
2017 Mundbjerg K, Chopra S, Alemozaffar M, Duymich C, Lakshminarasimhan R, Nichols PW, Aron M, Siegmund KD, Ukimura O, Aron M, Stern M, Gill P, Carpten JD, Ørntoft TF, Sørensen KD, ... ... Jones PA, et al. Identifying aggressive prostate cancer foci using a DNA methylation classifier. Genome Biology. 18: 3. PMID 28081708 DOI: 10.1186/s13059-016-1129-3  0.72
2016 Connolly R, Li H, Jankowitz RC, Zhang Z, Rudek MA, Jeter SC, Slater S, Powers P, Wolff AC, Fetting JH, Brufsky AM, Piekarz R, Ahuja N, Laird PW, Shen H, ... ... Jones PA, et al. Combination Epigenetic Therapy in Advanced Breast Cancer with 5-Azacitidine and Entinostat: A Phase II National Cancer Institute/Stand Up to Cancer Study. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27979916 DOI: 10.1158/1078-0432.CCR-16-1729  0.6
2016 Liu M, Ohtani H, Zhou W, Ørskov AD, Charlet J, Zhang YW, Shen H, Baylin SB, Liang G, Grønbæk K, Jones PA. Vitamin C increases viral mimicry induced by 5-aza-2'-deoxycytidine. Proceedings of the National Academy of Sciences of the United States of America. PMID 27573823 DOI: 10.1073/pnas.1612262113  1
2016 Baylin SB, Jones PA. Epigenetic Determinants of Cancer. Cold Spring Harbor Perspectives in Biology. PMID 27194046 DOI: 10.1101/cshperspect.a019505  0.36
2016 Charlet J, Duymich CE, Lay FD, Mundbjerg K, Dalsgaard Sørensen K, Liang G, Jones PA. Bivalent Regions of Cytosine Methylation and H3K27 Acetylation Suggest an Active Role for DNA Methylation at Enhancers. Molecular Cell. 62: 422-31. PMID 27153539 DOI: 10.1016/j.molcel.2016.03.033  1
2016 Duymich CE, Charlet J, Yang X, Jones PA, Liang G. DNMT3B isoforms without catalytic activity stimulate gene body methylation as accessory proteins in somatic cells. Nature Communications. 7: 11453. PMID 27121154 DOI: 10.1038/ncomms11453  0.72
2016 Becket E, Chopra S, Duymich CE, Lin JJ, You JS, Pandiyan K, Nichols PW, Siegmund KD, Charlet J, Weisenberger DJ, Jones PA, Liang G. Identification of DNA methylation-independent epigenetic events underlying clear cell renal cell carcinoma. Cancer Research. PMID 26759245 DOI: 10.1158/0008-5472.CAN-15-2622  1
2016 Pandiyan K, Jones PA, Baylin SB. CHAPTER 10: Dosing - When less is more Rsc Drug Discovery Series. 2016: 249-266. DOI: 10.1039/9781782628484-00249  0.4
2015 Statham AL, Taberlay PC, Kelly TK, Jones PA, Clark SJ. Genome-wide nucleosome occupancy and DNA methylation profiling of four human cell lines. Genomics Data. 3: 94-6. PMID 26484155 DOI: 10.1016/j.gdata.2014.11.012  0.64
2015 Jones PA, Herrington LC, Graham-Smith P. Technique determinants of knee abduction moments during pivoting in female soccer players. Clinical Biomechanics (Bristol, Avon). PMID 26432414 DOI: 10.1016/j.clinbiomech.2015.09.012  0.6
2015 Comfort P, Jones PA, Smith LC, Herrington L. Joint Kinetics and Kinematics During Common Lower Limb Rehabilitation Exercises. Journal of Athletic Training. 50: 1011-8. PMID 26418958 DOI: 10.4085/1062-6050-50.9.05  0.6
2015 Roulois D, Loo Yau H, Singhania R, Wang Y, Danesh A, Shen SY, Han H, Liang G, Jones PA, Pugh TJ, O'Brien C, De Carvalho DD. DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts. Cell. 162: 961-73. PMID 26317465 DOI: 10.1016/j.cell.2015.07.056  1
2015 Barber OR, Thomas C, Jones PA, McMahon JJ, Comfort P. Reliability of the 505 Change of Direction Test in Netball Players. International Journal of Sports Physiology and Performance. PMID 26309330 DOI: 10.1123/ijspp.2015-0215  0.6
2015 Dos'Santos T, Jones PA, Kelly J, McMahon JJ, Comfort P, Thomas C. Effect of Sampling Frequency on Isometric Mid-Thigh Pull Kinetics. International Journal of Sports Physiology and Performance. PMID 26217049 DOI: 10.1123/ijspp.2015-0222  0.6
2015 Thomas C, Dos'Santos T, Jones PA, Comfort P. Reliability of the 30-15 Intermittent Fitness Test in Semi-Professional Soccer Players. International Journal of Sports Physiology and Performance. PMID 26181081 DOI: 10.1123/ijspp.2015-0056  0.6
2015 Fulkerson CM, Dhawan D, Jones DR, Marquez VE, Jones PA, Wang Z, Wu Q, Klaunig JE, Fourez LM, Bonney PL, Knapp DW. Pharmacokinetics and toxicity of the novel oral demethylating agent zebularine in laboratory and tumor bearing dogs. Veterinary and Comparative Oncology. PMID 26178438 DOI: 10.1111/vco.12159  0.44
2015 Jones PA, Herrington LC, Graham-Smith P. Technique determinants of knee joint loads during cutting in female soccer players. Human Movement Science. 42: 203-211. PMID 26057866 DOI: 10.1016/j.humov.2015.05.004  0.6
2015 Comfort P, Jones PA, Udall R. The effect of load and sex on kinematic and kinetic variables during the mid-thigh clean pull. Sports Biomechanics / International Society of Biomechanics in Sports. 1-18. PMID 25896197 DOI: 10.1080/14763141.2015.1025237  0.6
2015 Jones P. ACP journal club. Review: ≤ 7 and > 7 days of systemic corticosteroids do not differ for efficacy in COPD exacerbations. Annals of Internal Medicine. 162: JC7. PMID 25775350 DOI: 10.7326/ACPJC-2015-162-6-007  0.6
2015 Lay FD, Liu Y, Kelly TK, Witt H, Farnham PJ, Jones PA, Berman BP. The role of DNA methylation in directing the functional organization of the cancer epigenome. Genome Research. 25: 467-77. PMID 25747664 DOI: 10.1101/gr.183368.114  1
2015 Thomas C, Jones PA, Rothwell J, Chiang CY, Comfort P. An Investigation into the Relationship between Maximum Isometric Strength and Vertical Jump Performance. Journal of Strength and Conditioning Research / National Strength & Conditioning Association. PMID 25647649 DOI: 10.1519/JSC.0000000000000866  0.6
2015 Morgan MK, Jones PA, Sobus JR, Chuang JC, Wilson NK. Using urinary biomarkers to evaluate polycyclic aromatic hydrocarbon exposure in 126 preschool children in Ohio. International Journal of Environmental Health Research. 1-12. PMID 25614176 DOI: 10.1080/09603123.2014.1003039  0.6
2015 Sconce E, Jones P, Turner E, Comfort P, Graham-Smith P. The validity of the nordic hamstring lower for a field-based assessment of eccentric hamstring strength. Journal of Sport Rehabilitation. 24: 13-20. PMID 25606859 DOI: 10.1123/JSR.2013-0097  0.6
2015 Morgan M, Jones P, Sobus J. Short-term variability and predictors of urinary pentachlorophenol levels in Ohio preschool children. International Journal of Environmental Research and Public Health. 12: 800-15. PMID 25594782 DOI: 10.3390/ijerph120100800  0.6
2015 Thomas C, Jones PA, Comfort P. Reliability of the Dynamic Strength Index in Collegiate Athletes. International Journal of Sports Physiology and Performance. 10: 542-5. PMID 25393233 DOI: 10.1123/ijspp.2014-0255  0.6
2015 Comfort P, Jones PA, McMahon JJ, Newton R. Effect of knee and trunk angle on kinetic variables during the isometric midthigh pull: test-retest reliability. International Journal of Sports Physiology and Performance. 10: 58-63. PMID 24912198 DOI: 10.1123/ijspp.2014-0077  0.6
2015 Statham AL, Taberlay PC, Kelly TK, Jones PA, Clark SJ. Genome-wide nucleosome occupancy and DNA methylation profiling of four human cell lines Genomics Data. 3: 94-96. DOI: 10.1016/j.gdata.2014.11.012  1
2015 Shin HH, Jones P, Brook R, Bard R, Oliver K, Williams R. Associations between personal exposures to VOCs and alterations in cardiovascular physiology: Detroit Exposure and Aerosol Research Study (DEARS) Atmospheric Environment. 104: 246-255. DOI: 10.1016/j.atmosenv.2015.01.016  0.6
2015 Matthews MJ, Jones P, Cohen D, Matthews H. The assisted nordic hamstring curl Strength and Conditioning Journal. 37: 84-87.  0.6
2014 Yang X, Han H, De Carvalho DD, Lay FD, Jones PA, Liang G. Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell. 26: 577-90. PMID 25263941 DOI: 10.1016/j.ccr.2014.07.028  1
2014 Alenezi F, Herrington L, Jones P, Jones R. The reliability of biomechanical variables collected during single leg squat and landing tasks Journal of Electromyography and Kinesiology. 24: 718-721. PMID 25128206 DOI: 10.1016/j.jelekin.2014.07.007  0.6
2014 Jones PA, Herrington LC, Munro AG, Graham-Smith P. Is there a relationship between landing, cutting, and pivoting tasks in terms of the characteristics of dynamic valgus? The American Journal of Sports Medicine. 42: 2095-102. PMID 25005852 DOI: 10.1177/0363546514539446  0.6
2014 Taberlay PC, Statham AL, Kelly TK, Clark SJ, Jones PA. Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer. Genome Research. 24: 1421-32. PMID 24916973 DOI: 10.1101/gr.163485.113  1
2014 Bampouras TM, Marrin K, Sankey SP, Jones PA. Test-retest reliability and sensitivity of the Concept2 Dyno dynamometer: practical applications. Journal of Strength and Conditioning Research / National Strength & Conditioning Association. 28: 1381-5. PMID 24755869 DOI: 10.1519/JSC.0000000000000269  0.6
2014 Su SF, de Castro Abreu AL, Chihara Y, Tsai Y, Andreu-Vieyra C, Daneshmand S, Skinner EC, Jones PA, Siegmund KD, Liang G. A panel of three markers hyper- and hypomethylated in urine sediments accurately predicts bladder cancer recurrence. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 1978-89. PMID 24691641 DOI: 10.1158/1078-0432.CCR-13-2637  1
2014 Li H, Chiappinelli KB, Guzzetta AA, Easwaran H, Yen RW, Vatapalli R, Topper MJ, Luo J, Connolly RM, Azad NS, Stearns V, Pardoll DM, Davidson N, Jones PA, Slamon DJ, et al. Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers. Oncotarget. 5: 587-98. PMID 24583822  1
2014 Lay FD, Triche TJ, Tsai YC, Su SF, Martin SE, Daneshmand S, Skinner EC, Liang G, Chihara Y, Jones PA. Reprogramming of the human intestinal epigenome by surgical tissue transposition. Genome Research. 24: 545-53. PMID 24515120 DOI: 10.1101/gr.166439.113  1
2014 Jones PA. At the tipping point for epigenetic therapies in cancer. The Journal of Clinical Investigation. 124: 14-6. PMID 24382384 DOI: 10.1172/JCI74145  1
2014 Pedersen JS, Valen E, Velazquez AM, Parker BJ, Rasmussen M, Lindgreen S, Lilje B, Tobin DJ, Kelly TK, Vang S, Andersson R, Jones PA, Hoover CA, Tikhonov A, Prokhortchouk E, et al. Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome. Genome Research. 24: 454-66. PMID 24299735 DOI: 10.1101/gr.163592.113  1
2014 Jeong KW, Andreu-Vieyra C, You JS, Jones PA, Stallcup MR. Establishment of active chromatin structure at enhancer elements by mixed-lineage leukemia 1 to initiate estrogen-dependent gene expression. Nucleic Acids Research. 42: 2245-56. PMID 24288367 DOI: 10.1093/nar/gkt1236  1
2014 Stevens C, Williams R, Jones P. Progress on understanding spatial and temporal variability of PM(2.5) and its components in the Detroit Exposure and Aerosol Research Study (DEARS). Environmental Science. Processes & Impacts. 16: 94-105. PMID 24247528 DOI: 10.1039/c3em00364g  0.6
2014 Jones PA, Liang G. The human epigenome Epigenetic Epidemiology. 5-20. DOI: 10.1007/978-94-007-2495-2_2  1
2013 Wrangle J, Wang W, Koch A, Easwaran H, Mohammad HP, Vendetti F, Vancriekinge W, Demeyer T, Du Z, Parsana P, Rodgers K, Yen RW, Zahnow CA, Taube JM, Brahmer JR, ... ... Jones PA, et al. Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine. Oncotarget. 4: 2067-79. PMID 24162015  1
2013 Morgan MK, Jones PA. Dietary predictors of young children's exposure to current-use pesticides using urinary biomonitoring. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 62: 131-41. PMID 23973405 DOI: 10.1016/j.fct.2013.08.029  0.6
2013 Choi IS, Yu K, Kim J, De Guzman E, Weisenberger DJ, Oghamian S, Kim HJ, Lee KH, Carroll C, Trinh BN, Kim M, Houshdaran S, Laird PW, Jones PA, Warburton D, et al. Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model. Urology. 82: 253.e9-15. PMID 23806407 DOI: 10.1016/j.urology.2013.04.010  1
2013 Chihara Y, Kanai Y, Fujimoto H, Sugano K, Kawashima K, Liang G, Jones PA, Fujimoto K, Kuniyasu H, Hirao Y. Diagnostic markers of urothelial cancer based on DNA methylation analysis. Bmc Cancer. 13: 275. PMID 23735005 DOI: 10.1186/1471-2407-13-275  1
2013 You JS, De Carvalho DD, Dai C, Liu M, Pandiyan K, Zhou XJ, Liang G, Jones PA. SNF5 is an essential executor of epigenetic regulation during differentiation. Plos Genetics. 9: e1003459. PMID 23637628 DOI: 10.1371/journal.pgen.1003459  1
2013 Pandiyan K, You JS, Yang X, Dai C, Zhou XJ, Baylin SB, Jones PA, Liang G. Functional DNA demethylation is accompanied by chromatin accessibility. Nucleic Acids Research. 41: 3973-85. PMID 23408854 DOI: 10.1093/nar/gkt077  1
2013 Graham-Smith P, Jones PA, Comfort P, Munro AG. Assessment of knee flexor and extensor muscle balance International Journal of Athletic Therapy and Training. 18: 1-5.  0.6
2012 Beck S, Bernstein BE, Campbell RM, Costello JF, Dhanak D, Ecker JR, Greally JM, Issa JP, Laird PW, Polyak K, Tycko B, Jones PA. A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force. Cancer Research. 72: 6319-24. PMID 23188507 DOI: 10.1158/0008-5472.CAN-12-3658  1
2012 Kelly TK, Liu Y, Lay FD, Liang G, Berman BP, Jones PA. Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules. Genome Research. 22: 2497-506. PMID 22960375 DOI: 10.1101/gr.143008.112  1
2012 You JS, Jones PA. Cancer genetics and epigenetics: two sides of the same coin? Cancer Cell. 22: 9-20. PMID 22789535 DOI: 10.1016/j.ccr.2012.06.008  0.4
2012 De Carvalho DD, Sharma S, You JS, Su SF, Taberlay PC, Kelly TK, Yang X, Liang G, Jones PA. DNA methylation screening identifies driver epigenetic events of cancer cell survival. Cancer Cell. 21: 655-67. PMID 22624715 DOI: 10.1016/j.ccr.2012.03.045  1
2012 Comfort P, Udall R, Jones PA. The effect of loading on kinematic and kinetic variables during the midthigh clean pull. Journal of Strength and Conditioning Research / National Strength & Conditioning Association. 26: 1208-14. PMID 22516901 DOI: 10.1519/JSC.0b013e3182510827n  0.6
2012 Yang X, Noushmehr H, Han H, Andreu-Vieyra C, Liang G, Jones PA. Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions. Plos Genetics. 8: e1002604. PMID 22479200 DOI: 10.1371/journal.pgen.1002604  1
2012 Sharma S, Gerke DS, Han HF, Jeong S, Stallcup MR, Jones PA, Liang G. Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells. Epigenetics & Chromatin. 5: 3. PMID 22284370 DOI: 10.1186/1756-8935-5-3  1
2012 Treppendahl MB, Qiu X, Søgaard A, Yang X, Nandrup-Bus C, Hother C, Andersen MK, Kjeldsen L, MöllgÃ¥rd L, Möllgaard L, Hellström-Lindberg E, Jendholm J, Porse BT, Jones PA, Liang G, et al. Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML. Blood. 119: 206-16. PMID 22058117 DOI: 10.1182/blood-2011-06-362541  0.72
2012 Williams R, Jones P, Croghan C, Thornburg J, Rodes C. The influence of human and environmental exposure factors on personal NO 2 exposures Journal of Exposure Science and Environmental Epidemiology. 22: 109-115. PMID 21540887 DOI: 10.1038/jes.2011.20  0.6
2012 Williams R, Rappold AG, Case M, Schmitt M, Stone S, Jones P, Thornburg J, Devlin RB. Multi-pollutant exposures in an asthmatic cohort Atmospheric Environment. 61: 244-252. DOI: 10.1016/j.atmosenv.2012.07.049  0.6
2011 Taberlay PC, Kelly TK, Liu CC, You JS, De Carvalho DD, Miranda TB, Zhou XJ, Liang G, Jones PA. Polycomb-repressed genes have permissive enhancers that initiate reprogramming. Cell. 147: 1283-94. PMID 22153073 DOI: 10.1016/j.cell.2011.10.040  1
2011 Andreu-Vieyra C, Lai J, Berman BP, Frenkel B, Jia L, Jones PA, Coetzee GA. Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells. Molecular and Cellular Biology. 31: 4648-62. PMID 21969603 DOI: 10.1128/MCB.05934-11  1
2011 Baylin SB, Jones PA. A decade of exploring the cancer epigenome - biological and translational implications. Nature Reviews. Cancer. 11: 726-34. PMID 21941284 DOI: 10.1038/nrc3130  0.36
2011 You JS, Kelly TK, De Carvalho DD, Taberlay PC, Liang G, Jones PA. OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes. Proceedings of the National Academy of Sciences of the United States of America. 108: 14497-502. PMID 21844352 DOI: 10.1073/pnas.1111309108  1
2011 Han H, Cortez CC, Yang X, Nichols PW, Jones PA, Liang G. DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter. Human Molecular Genetics. 20: 4299-310. PMID 21835883 DOI: 10.1093/hmg/ddr356  1
2011 Morgan MK, Jones PA, Calafat AM, Ye X, Croghan CW, Chuang JC, Wilson NK, Clifton MS, Figueroa Z, Sheldon LS. Assessing the quantitative relationships between preschool children's exposures to bisphenol A by route and urinary biomonitoring. Environmental Science & Technology. 45: 5309-16. PMID 21612268 DOI: 10.1021/es200537u  0.6
2011 Molognoni F, Cruz AT, Meliso FM, Morais AS, Souza CF, Xander P, Bischof JM, Costa FF, Soares MB, Liang G, Jones PA, Jasiulionis MG. Epigenetic reprogramming as a key contributor to melanocyte malignant transformation. Epigenetics : Official Journal of the Dna Methylation Society. 6: 450-64. PMID 21343701 DOI: 10.4161/epi.6.4.14917  1
2011 Sharma S, De Carvalho DD, Jeong S, Jones PA, Liang G. Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance. Plos Genetics. 7: e1001286. PMID 21304883 DOI: 10.1371/journal.pgen.1001286  1
2011 Kelly TK, Jones PA. Role of nucleosomes in mitotic bookmarking. Cell Cycle (Georgetown, Tex.). 10: 370-1. PMID 21270523 DOI: 10.4161/cc.10.3.14734  1
2011 Taberlay PC, Jones PA. DNA methylation and cancer. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. ProgrèS Des Recherches Pharmaceutiques. 67: 1-23. PMID 21141722 DOI: 10.1007/978-3-7643-8989-5_1  1
2011 Morgan MK, Sheldon LS, Jones PA, Croghan CW, Chuang JC, Wilson NK. The reliability of using urinary biomarkers to estimate children's exposures to chlorpyrifos and diazinon. Journal of Exposure Science & Environmental Epidemiology. 21: 280-90. PMID 20502492 DOI: 10.1038/jes.2010.11  0.6
2010 Kelly TK, De Carvalho DD, Jones PA. Epigenetic modifications as therapeutic targets. Nature Biotechnology. 28: 1069-78. PMID 20944599 DOI: 10.1038/nbt.1678  1
2010 Qiu X, Hother C, Ralfkiær UM, Søgaard A, Lu Q, Workman CT, Liang G, Jones PA, Grønbæk K. Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome. Plos One. 5. PMID 20927380 DOI: 10.1371/journal.pone.0012994  1
2010 Kelly TK, Miranda TB, Liang G, Berman BP, Lin JC, Tanay A, Jones PA. H2A.Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes. Molecular Cell. 39: 901-11. PMID 20864037 DOI: 10.1016/j.molcel.2010.08.026  1
2010 Yang X, Lay F, Han H, Jones PA. Targeting DNA methylation for epigenetic therapy. Trends in Pharmacological Sciences. 31: 536-46. PMID 20846732 DOI: 10.1016/j.tips.2010.08.001  1
2010 Wolff EM, Chihara Y, Pan F, Weisenberger DJ, Siegmund KD, Sugano K, Kawashima K, Laird PW, Jones PA, Liang G. Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue. Cancer Research. 70: 8169-78. PMID 20841482 DOI: 10.1158/0008-5472.CAN-10-1335  1
2010 De Carvalho DD, You JS, Jones PA. DNA methylation and cellular reprogramming. Trends in Cell Biology. 20: 609-17. PMID 20810283 DOI: 10.1016/j.tcb.2010.08.003  0.4
2010 Jones PA, Bampouras TM. A comparison of isokinetic and functional methods of assessing bilateral strength imbalance. Journal of Strength and Conditioning Research / National Strength & Conditioning Association. 24: 1553-8. PMID 20508458 DOI: 10.1519/JSC.0b013e3181dc4392  0.6
2010 Chuang JC, Warner SL, Vollmer D, Vankayalapati H, Redkar S, Bearss DJ, Qiu X, Yoo CB, Jones PA. S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth. Molecular Cancer Therapeutics. 9: 1443-50. PMID 20442312 DOI: 10.1158/1535-7163.MCT-09-1048  1
2010 Wolff EM, Byun HM, Han HF, Sharma S, Nichols PW, Siegmund KD, Yang AS, Jones PA, Liang G. Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer. Plos Genetics. 6: e1000917. PMID 20421991 DOI: 10.1371/journal.pgen.1000917  1
2010 Miranda TB, Kelly TK, Bouazoune K, Jones PA. Methylation-sensitive single-molecule analysis of chromatin structure. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 21.17.1-16. PMID 20069538 DOI: 10.1002/0471142727.mb2117s89  1
2010 Thomas KW, Dosemeci M, Coble JB, Hoppin JA, Sheldon LS, Chapa G, Croghan CW, Jones PA, Knott CE, Lynch CF, Sandler DP, Blair AE, Alavanja MC. Assessment of a pesticide exposure intensity algorithm in the agricultural health study. Journal of Exposure Science & Environmental Epidemiology. 20: 559-69. PMID 19888312 DOI: 10.1038/jes.2009.54  0.6
2010 Sharma S, Kelly TK, Jones PA. Epigenetics in cancer. Carcinogenesis. 31: 27-36. PMID 19752007 DOI: 10.1093/carcin/bgp220  1
2009 Ricca TI, Liang G, Suenaga AP, Han SW, Jones PA, Jasiulionis MG. Tissue inhibitor of metalloproteinase 1 expression associated with gene demethylation confers anoikis resistance in early phases of melanocyte malignant transformation. Translational Oncology. 2: 329-40. PMID 19956395  0.72
2009 Jones PA, Liang G. Rethinking how DNA methylation patterns are maintained. Nature Reviews. Genetics. 10: 805-11. PMID 19789556 DOI: 10.1038/nrg2651  0.72
2009 Friedman JM, Jones PA. MicroRNAs: critical mediators of differentiation, development and disease. Swiss Medical Weekly. 139: 466-72. PMID 19705306  0.36
2009 Friedman JM, Jones PA, Liang G. The tumor suppressor microRNA-101 becomes an epigenetic player by targeting the polycomb group protein EZH2 in cancer. Cell Cycle (Georgetown, Tex.). 8: 2313-4. PMID 19625769  0.72
2009 Jeong S, Liang G, Sharma S, Lin JC, Choi SH, Han H, Yoo CB, Egger G, Yang AS, Jones PA. Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA. Molecular and Cellular Biology. 29: 5366-76. PMID 19620278 DOI: 10.1128/MCB.00484-09  1
2009 Stout DM, Bradham KD, Egeghy PP, Jones PA, Croghan CW, Ashley PA, Pinzer E, Friedman W, Brinkman MC, Nishioka MG, Cox DC. American Healthy Homes Survey: a national study of residential pesticides measured from floor wipes. Environmental Science & Technology. 43: 4294-300. PMID 19603637 DOI: 10.1021/es8030243  0.6
2009 Bouazoune K, Miranda TB, Jones PA, Kingston RE. Analysis of individual remodeled nucleosomes reveals decreased histone-DNA contacts created by hSWI/SNF. Nucleic Acids Research. 37: 5279-94. PMID 19567737 DOI: 10.1093/nar/gkp524  1
2009 Miranda TB, Cortez CC, Yoo CB, Liang G, Abe M, Kelly TK, Marquez VE, Jones PA. DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation. Molecular Cancer Therapeutics. 8: 1579-88. PMID 19509260 DOI: 10.1158/1535-7163.MCT-09-0013  1
2009 Friedman JM, Liang G, Liu CC, Wolff EM, Tsai YC, Ye W, Zhou X, Jones PA. The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2. Cancer Research. 69: 2623-9. PMID 19258506 DOI: 10.1158/0008-5472.CAN-08-3114  1
2009 Jones P, Bampouras TM, Marrin K. An investigation into the physical determinants of change of direction speed Journal of Sports Medicine and Physical Fitness. 49: 97-104. PMID 19188902  0.6
2009 Jones P. Old song; obama; human element [4] World Affairs. 171: 103. DOI: 10.3200/WAFS.171.4.102-104  0.6
2008 Yoo CB, Chuang JC, Byun HM, Egger G, Yang AS, Dubeau L, Long T, Laird PW, Marquez VE, Jones PA. Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice. Cancer Prevention Research (Philadelphia, Pa.). 1: 233-40. PMID 19138966 DOI: 10.1158/1940-6207.CAPR-07-0008  1
2008 Yoo CB, Valente R, Congiatu C, Gavazza F, Angel A, Siddiqui MA, Jones PA, McGuigan C, Marquez VE. Activation of p16 gene silenced by DNA methylation in cancer cells by phosphoramidate derivatives of 2'-deoxyzebularine. Journal of Medicinal Chemistry. 51: 7593-601. PMID 19006382 DOI: 10.1021/jm8005965  1
2008 Gal-Yam EN, Egger G, Iniguez L, Holster H, Einarsson S, Zhang X, Lin JC, Liang G, Jones PA, Tanay A. Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line. Proceedings of the National Academy of Sciences of the United States of America. 105: 12979-84. PMID 18753622 DOI: 10.1073/pnas.0806437105  1
2008 Cortez CC, Jones PA. Chromatin, cancer and drug therapies. Mutation Research. 647: 44-51. PMID 18691602 DOI: 10.1016/j.mrfmmm.2008.07.006  1
2008 Wolff EM, Liang G, Cortez CC, Tsai YC, Castelao JE, Cortessis VK, Tsao-Wei DD, Groshen S, Jones PA. RUNX3 methylation reveals that bladder tumors are older in patients with a history of smoking. Cancer Research. 68: 6208-14. PMID 18676844 DOI: 10.1158/0008-5472.CAN-07-6616  1
2008 Weisenberger DJ, Trinh BN, Campan M, Sharma S, Long TI, Ananthnarayan S, Liang G, Esteva FJ, Hortobagyi GN, McCormick F, Jones PA, Laird PW. DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight. Nucleic Acids Research. 36: 4689-98. PMID 18628296 DOI: 10.1093/nar/gkn455  1
2008 van Rietschoten JG, Gal-Yam EN, Jeong S, Cortez CC, Verweij CL, Jones PA. Epigenetic regulation and nucleosome positioning in the human TATA-less IL-1 alpha promoter. Genes and Immunity. 9: 582-90. PMID 18615092 DOI: 10.1038/gene.2008.53  1
2008 Morgan MK, Stout DM, Jones PA, Barr DB. An observational study of the potential for human exposures to pet-borne diazinon residues following lawn applications. Environmental Research. 107: 336-42. PMID 18448091 DOI: 10.1016/j.envres.2008.03.004  0.6
2008 Morgan MK, Sheldon LS, Thomas KW, Egeghy PP, Croghan CW, Jones PA, Chuang JC, Wilson NK. Adult and children's exposure to 2,4-D from multiple sources and pathways. Journal of Exposure Science & Environmental Epidemiology. 18: 486-94. PMID 18167507 DOI: 10.1038/sj.jes.7500641  0.6
2008 Gal-Yam EN, Saito Y, Egger G, Jones PA. Cancer epigenetics: modifications, screening, and therapy. Annual Review of Medicine. 59: 267-80. PMID 17937590 DOI: 10.1146/annurev.med.59.061606.095816  0.52
2007 George B, Datar RH, Wu L, Cai J, Patten N, Beil SJ, Groshen S, Stein J, Skinner D, Jones PA, Cote RJ. p53 gene and protein status: the role of p53 alterations in predicting outcome in patients with bladder cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 5352-8. PMID 18048815 DOI: 10.1200/JCO.2006.10.4125  0.44
2007 Lin JC, Jeong S, Liang G, Takai D, Fatemi M, Tsai YC, Egger G, Gal-Yam EN, Jones PA. Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island. Cancer Cell. 12: 432-44. PMID 17996647 DOI: 10.1016/j.ccr.2007.10.014  0.72
2007 Tulve NS, Jones PA, McCurdy T, Croghan CW. A pilot study using an accelerometer to evaluate a caregiver's interpretation of an infant or toddler's activity level as recorded in a time activity diary. Research Quarterly For Exercise and Sport. 78: 375-83. PMID 17941542 DOI: 10.1080/02701367.2007.10599435  0.6
2007 Miranda TB, Jones PA. DNA methylation: the nuts and bolts of repression. Journal of Cellular Physiology. 213: 384-90. PMID 17708532 DOI: 10.1002/jcp.21224  1
2007 Yoo CB, Jeong S, Egger G, Liang G, Phiasivongsa P, Tang C, Redkar S, Jones PA. Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides. Cancer Research. 67: 6400-8. PMID 17616700 DOI: 10.1158/0008-5472.CAN-07-0251  1
2007 Chuang JC, Jones PA. Epigenetics and microRNAs. Pediatric Research. 61: 24R-29R. PMID 17413852 DOI: 10.1203/pdr.0b013e3180457684  1
2007 Jones PA, Baylin SB. The epigenomics of cancer. Cell. 128: 683-92. PMID 17320506 DOI: 10.1016/j.cell.2007.01.029  0.36
2007 Morgan MK, Sheldon LS, Croghan CW, Jones PA, Chuang JC, Wilson NK. An observational study of 127 preschool children at their homes and daycare centers in Ohio: environmental pathways to cis- and trans-permethrin exposure. Environmental Research. 104: 266-74. PMID 17258193 DOI: 10.1016/j.envres.2006.11.011  0.6
2007 Egger G, Aparicio AM, Escobar SG, Jones PA. Inhibition of histone deacetylation does not block resilencing of p16 after 5-aza-2'-deoxycytidine treatment. Cancer Research. 67: 346-53. PMID 17210717 DOI: 10.1158/0008-5472.CAN-06-2845  1
2007 Jones P, Bampouras TM. Resistance training for distance running: A brief update Strength and Conditioning Journal. 29: 28-35.  0.6
2006 Tulve NS, Jones PA, Nishioka MG, Fortmann RC, Croghan CW, Zhou JY, Fraser A, Cavel C, Friedman W. Pesticide measurements from the first national environmental health survey of child care centers using a multi-residue GC/MS analysis method. Environmental Science & Technology. 40: 6269-74. PMID 17120552 DOI: 10.1021/es061021h  0.6
2006 Saito Y, Jones PA. Epigenetic activation of tumor suppressor microRNAs in human cancer cells. Cell Cycle (Georgetown, Tex.). 5: 2220-2. PMID 17012846  0.36
2006 Gal-Yam EN, Jeong S, Tanay A, Egger G, Lee AS, Jones PA. Constitutive nucleosome depletion and ordered factor assembly at the GRP78 promoter revealed by single molecule footprinting. Plos Genetics. 2: e160. PMID 17002502 DOI: 10.1371/journal.pgen.0020160  0.52
2006 Jia L, Shen HC, Wantroba M, Khalid O, Liang G, Wang Q, Gentzschein E, Pinski JK, Stanczyk FZ, Jones PA, Coetzee GA. Locus-wide chromatin remodeling and enhanced androgen receptor-mediated transcription in recurrent prostate tumor cells. Molecular and Cellular Biology. 26: 7331-41. PMID 16980632 DOI: 10.1128/MCB.00581-06  1
2006 Egger G, Jeong S, Escobar SG, Cortez CC, Li TW, Saito Y, Yoo CB, Jones PA, Liang G. Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival. Proceedings of the National Academy of Sciences of the United States of America. 103: 14080-5. PMID 16963560 DOI: 10.1073/pnas.0604602103  1
2006 van Rietschoten JG, Verzijlbergen KF, Gringhuis SI, van der Pouw Kraan TC, Bayley JP, Wierenga EA, Jones PA, Kooter JM, Verweij CL. Differentially methylated alleles in a distinct region of the human interleukin-1alpha promoter are associated with allele-specific expression of IL-1alpha in CD4+ T cells. Blood. 108: 2143-9. PMID 16788102 DOI: 10.1182/blood-2006-01-021147  0.4
2006 Saito Y, Liang G, Egger G, Friedman JM, Chuang JC, Coetzee GA, Jones PA. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell. 9: 435-43. PMID 16766263 DOI: 10.1016/j.ccr.2006.04.020  1
2006 Yoo CB, Jones PA. Epigenetic therapy of cancer: past, present and future. Nature Reviews. Drug Discovery. 5: 37-50. PMID 16485345 DOI: 10.1038/nrd1930  1
2006 Williams RW, Vette A, Whitaker DA, Croghan CW, Jones PA, Daughtrey EH, Oliver KD, Jacumin HH, Williams DD, Rodes CE, Thornburg JW, Herrington JS, Zhang L, Tong J, Zhang J. Use of passive samplers in the DEARS Air and Waste Management Association - Symposium On Air Quality Measurement: Methods and Technology 2006. 386-390.  0.6
2005 Wolff EM, Liang G, Jones PA. Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer. Nature Clinical Practice. Urology. 2: 502-10. PMID 16474624 DOI: 10.1038/ncpuro0318  1
2005 Marquez VE, Kelley JA, Agbaria R, Ben-Kasus T, Cheng JC, Yoo CB, Jones PA. Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. Annals of the New York Academy of Sciences. 1058: 246-54. PMID 16394141 DOI: 10.1196/annals.1359.037  1
2005 Fatemi M, Pao MM, Jeong S, Gal-Yam EN, Egger G, Weisenberger DJ, Jones PA. Footprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level. Nucleic Acids Research. 33: e176. PMID 16314307 DOI: 10.1093/nar/gni180  1
2005 Marquez VE, Barchi JJ, Kelley JA, Rao KV, Agbaria R, Ben-Kasus T, Cheng JC, Yoo CB, Jones PA. Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology. Nucleosides, Nucleotides & Nucleic Acids. 24: 305-18. PMID 16247946 DOI: 10.1081/NCN-200059765  1
2005 Friedrich MG, Chandrasoma S, Siegmund KD, Weisenberger DJ, Cheng JC, Toma MI, Huland H, Jones PA, Liang G. Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinoma. European Journal of Cancer (Oxford, England : 1990). 41: 2769-78. PMID 16242928 DOI: 10.1016/j.ejca.2005.07.019  1
2005 Chuang JC, Yoo CB, Kwan JM, Li TW, Liang G, Yang AS, Jones PA. Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine. Molecular Cancer Therapeutics. 4: 1515-20. PMID 16227400 DOI: 10.1158/1535-7163.MCT-05-0172  1
2005 Takai N, Kawamata N, Walsh CS, Gery S, Desmond JC, Whittaker S, Said JW, Popoviciu LM, Jones PA, Miyakawa I, Koeffler HP. Discovery of epigenetically masked tumor suppressor genes in endometrial cancer. Molecular Cancer Research : McR. 3: 261-9. PMID 15886297 DOI: 10.1158/1541-7786.MCR-04-0110  1
2005 Morgan MK, Sheldon LS, Croghan CW, Jones PA, Robertson GL, Chuang JC, Wilson NK, Lyu CW. Exposures of preschool children to chlorpyrifos and its degradation product 3,5,6-trichloro-2-pyridinol in their everyday environments. Journal of Exposure Analysis and Environmental Epidemiology. 15: 297-309. PMID 15367928 DOI: 10.1038/sj.jea.7500406  0.6
2004 Friedrich MG, Weisenberger DJ, Cheng JC, Chandrasoma S, Siegmund KD, Gonzalgo ML, Toma MI, Huland H, Yoo C, Tsai YC, Nichols PW, Bochner BH, Jones PA, Liang G. Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 7457-65. PMID 15569975 DOI: 10.1158/1078-0432.CCR-04-0930  1
2004 Yoo CB, Cheng JC, Jones PA. Zebularine: a new drug for epigenetic therapy. Biochemical Society Transactions. 32: 910-2. PMID 15506921 DOI: 10.1042/BST0320910  1
2004 Cheng JC, Yoo CB, Weisenberger DJ, Chuang J, Wozniak C, Liang G, Marquez VE, Greer S, Orntoft TF, Thykjaer T, Jones PA. Preferential response of cancer cells to zebularine. Cancer Cell. 6: 151-8. PMID 15324698 DOI: 10.1016/j.ccr.2004.06.023  1
2004 Widschwendter M, Siegmund KD, Müller HM, Fiegl H, Marth C, Müller-Holzner E, Jones PA, Laird PW. Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen. Cancer Research. 64: 3807-13. PMID 15172987 DOI: 10.1158/0008-5472.CAN-03-3852  1
2004 Egger G, Liang G, Aparicio A, Jones PA. Epigenetics in human disease and prospects for epigenetic therapy. Nature. 429: 457-63. PMID 15164071 DOI: 10.1038/nature02625  0.72
2004 Liang G, Lin JC, Wei V, Yoo C, Cheng JC, Nguyen CT, Weisenberger DJ, Egger G, Takai D, Gonzales FA, Jones PA. Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome. Proceedings of the National Academy of Sciences of the United States of America. 101: 7357-62. PMID 15123803 DOI: 10.1073/pnas.0401866101  1
2004 Weisenberger DJ, Velicescu M, Cheng JC, Gonzales FA, Liang G, Jones PA. Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation. Molecular Cancer Research : McR. 2: 62-72. PMID 14757847  1
2004 Cheng JC, Weisenberger DJ, Gonzales FA, Liang G, Xu GL, Hu YG, Marquez VE, Jones PA. Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells. Molecular and Cellular Biology. 24: 1270-8. PMID 14729971 DOI: 10.1128/MCB.24.3.1270-1278.2004  1
2003 Jones P, Lees A. A Biomechanical Analysis of the Acute Effects of Complex Training Using Lower Limb Exercises Journal of Strength and Conditioning Research. 17: 694-700. PMID 14636090 DOI: 10.1519/1533-4287(2003)017<0694:ABAOTA>2.0.CO;2  0.6
2003 Hsieh CL, Jones PA. Meddling with methylation. Nature Cell Biology. 5: 502-4. PMID 12776125 DOI: 10.1038/ncb0603-502  0.4
2003 Cheng JC, Matsen CB, Gonzales FA, Ye W, Greer S, Marquez VE, Jones PA, Selker EU. Inhibition of DNA methylation and reactivation of silenced genes by zebularine. Journal of the National Cancer Institute. 95: 399-409. PMID 12618505  1
2002 Nguyen CT, Weisenberger DJ, Velicescu M, Gonzales FA, Lin JC, Liang G, Jones PA. Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine. Cancer Research. 62: 6456-61. PMID 12438235  1
2002 Weisenberger DJ, Velicescu M, Preciado-Lopez MA, Gonzales FA, Tsai YC, Liang G, Jones PA. Identification and characterization of alternatively spliced variants of DNA methyltransferase 3a in mammalian cells. Gene. 298: 91-9. PMID 12406579 DOI: 10.1016/S0378-1119(02)00976-9  1
2002 Daskalakis M, Nguyen TT, Nguyen C, Guldberg P, Köhler G, Wijermans P, Jones PA, Lübbert M. Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment. Blood. 100: 2957-64. PMID 12351408 DOI: 10.1182/blood.V100.8.2957  0.32
2002 Liang G, Gonzalgo ML, Salem C, Jones PA. Identification of DNA methylation differences during tumorigenesis by methylation-sensitive arbitrarily primed polymerase chain reaction. Methods (San Diego, Calif.). 27: 150-5. PMID 12095274  0.72
2002 Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nature Reviews. Genetics. 3: 415-28. PMID 12042769 DOI: 10.1038/nrg816  0.36
2002 Velicescu M, Weisenberger DJ, Gonzales FA, Tsai YC, Nguyen CT, Jones PA. Cell division is required for de novo methylation of CpG islands in bladder cancer cells. Cancer Research. 62: 2378-84. PMID 11956100  1
2002 Liang G, Gonzales FA, Jones PA, Orntoft TF, Thykjaer T. Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine. Cancer Research. 62: 961-6. PMID 11861364  1
2002 Liang G, Chan MF, Tomigahara Y, Tsai YC, Gonzales FA, Li E, Laird PW, Jones PA. Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Molecular and Cellular Biology. 22: 480-91. PMID 11756544 DOI: 10.1128/MCB.22.2.480-491.2002  1
2001 Takai D, Gonzales FA, Tsai YC, Thayer MJ, Jones PA. Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer. Human Molecular Genetics. 10: 2619-26. PMID 11726548  1
2001 Nguyen CT, Gonzales FA, Jones PA. Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: correlation of accessibility, methylation, MeCP2 binding and acetylation. Nucleic Acids Research. 29: 4598-606. PMID 11713309  1
2001 Chan MF, van Amerongen R, Nijjar T, Cuppen E, Jones PA, Laird PW. Reduced rates of gene loss, gene silencing, and gene mutation in Dnmt1-deficient embryonic stem cells. Molecular and Cellular Biology. 21: 7587-600. PMID 11604495 DOI: 10.1128/MCB.21.22.7587-7600.2001  1
2001 Nguyen C, Liang G, Nguyen TT, Tsao-Wei D, Groshen S, Lübbert M, Zhou JH, Benedict WF, Jones PA. Susceptibility of nonpromoter CpG islands to de novo methylation in normal and neoplastic cells. Journal of the National Cancer Institute. 93: 1465-72. PMID 11584062  0.72
2001 Markl ID, Cheng J, Liang G, Shibata D, Laird PW, Jones PA. Global and gene-specific epigenetic patterns in human bladder cancer genomes are relatively stable in vivo and in vitro over time. Cancer Research. 61: 5875-84. PMID 11479229  1
2001 Xiong Z, Wu AH, Bender CM, Tsao JL, Blake C, Shibata D, Jones PA, Yu MC, Ross RK, Laird PW. Mismatch repair deficiency and CpG island hypermethylation in sporadic colon adenocarcinomas. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 10: 799-803. PMID 11440966  1
2001 Pao MM, Tsutsumi M, Liang G, Uzvolgyi E, Gonzales FA, Jones PA. The endothelin receptor B (EDNRB) promoter displays heterogeneous, site specific methylation patterns in normal and tumor cells. Human Molecular Genetics. 10: 903-10. PMID 11309363  1
2000 Liang G, Robertson KD, Talmadge C, Sumegi J, Jones PA. The gene for a novel transmembrane protein containing epidermal growth factor and follistatin domains is frequently hypermethylated in human tumor cells. Cancer Research. 60: 4907-12. PMID 10987305  0.72
2000 Tsao JL, Yatabe Y, Markl ID, Hajyan K, Jones PA, Shibata D. Bladder cancer genotype stability during clinical progression. Genes, Chromosomes & Cancer. 29: 26-32. PMID 10918390 DOI: 10.1002/1098-2264(2000)9999:9999<::AID-GCC1002>3.0.CO;2-X  1
2000 Salem CE, Markl ID, Bender CM, Gonzales FA, Jones PA, Liang G. PAX6 methylation and ectopic expression in human tumor cells. International Journal of Cancer. Journal International Du Cancer. 87: 179-85. PMID 10861471 DOI: 10.1002/1097-0215(20000715)87:2<179::AID-IJC4>3.0.CO;2-X  1
2000 Sarasua SM, Vogt RF, Henderson LO, Jones PA, Lybarger JA. Serum immunoglobulins and lymphocyte subset distributions in children and adults living in communities assessed for lead and cadmium exposure. Journal of Toxicology and Environmental Health. Part A. 60: 1-15. PMID 10832614  0.6
2000 Salem C, Liang G, Tsai YC, Coulter J, Knowles MA, Feng AC, Groshen S, Nichols PW, Jones PA. Progressive increases in de novo methylation of CpG islands in bladder cancer. Cancer Research. 60: 2473-6. PMID 10811126  0.72
2000 Chan MF, Liang G, Jones PA. Relationship between transcription and DNA methylation. Current Topics in Microbiology and Immunology. 249: 75-86. PMID 10802939  0.72
2000 Nguyen TT, Nguyen CT, Gonzales FA, Nichols PW, Yu MC, Jones PA. Analysis of cyclin-dependent kinase inhibitor expression and methylation patterns in human prostate cancers. The Prostate. 43: 233-42. PMID 10797499 DOI: 10.1002/(SICI)1097-0045(20000515)43:3<233::AID-PROS10>3.0.CO;2-S  1
2000 Nguyen TT, Mohrbacher AF, Tsai YC, Groffen J, Heisterkamp N, Nichols PW, Yu MC, Lübbert M, Jones PA. Quantitative measure of c-abl and p15 methylation in chronic myelogenous leukemia: biological implications. Blood. 95: 2990-2. PMID 10779450  0.6
2000 Robertson KD, Keyomarsi K, Gonzales FA, Velicescu M, Jones PA. Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells. Nucleic Acids Research. 28: 2108-13. PMID 10773079  1
2000 Pao MM, Liang G, Tsai YC, Xiong Z, Laird PW, Jones PA. DNA methylator and mismatch repair phenotypes are not mutually exclusive in colorectal cancer cell lines. Oncogene. 19: 943-52. PMID 10702803 DOI: 10.1038/sj.onc.1203414  1
2000 Robertson KD, Jones PA. DNA methylation: past, present and future directions. Carcinogenesis. 21: 461-7. PMID 10688866  0.32
2000 Lynch RA, Phillips ML, Jones P. Adverse impact on ponds of organic debris deposited by tornadoes Journal of Environmental Health. 63: 9-15.  0.6
1999 Bender CM, Gonzalgo ML, Gonzales FA, Nguyen CT, Robertson KD, Jones PA. Roles of cell division and gene transcription in the methylation of CpG islands. Molecular and Cellular Biology. 19: 6690-8. PMID 10490608  1
1999 Robertson KD, Jones PA. Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus. Oncogene. 18: 3810-20. PMID 10445844 DOI: 10.1038/sj.onc.1202737  0.32
1999 Lewin MD, Sarasua S, Jones PA. A multivariate linear regression model for predicting children's blood lead levels based on soil lead levels: A study at four superfund sites. Environmental Research. 81: 52-61. PMID 10361026 DOI: 10.1006/enrs.1998.3952  0.6
1999 Robertson KD, Uzvolgyi E, Liang G, Talmadge C, Sumegi J, Gonzales FA, Jones PA. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Research. 27: 2291-8. PMID 10325416 DOI: 10.1093/nar/27.11.2291  1
1999 Tsutsumi M, Liang G, Jones PA. Novel endothelin B receptor transcripts with the potential of generating a new receptor. Gene. 228: 43-9. PMID 10072757  0.72
1999 Jones PA, Laird PW. Cancer epigenetics comes of age. Nature Genetics. 21: 163-7. PMID 9988266 DOI: 10.1038/5947  1
1998 Tsutsumi M, Tsai YC, Gonzalgo ML, Nichols PW, Jones PA. Early acquisition of homozygous deletions of p16/p19 during squamous cell carcinogenesis and genetic mosaicism in bladder cancer. Oncogene. 17: 3021-7. PMID 9881704 DOI: 10.1038/sj.onc.1202228  0.6
1998 Markl ID, Jones PA. Presence and location of TP53 mutation determines pattern of CDKN2A/ARF pathway inactivation in bladder cancer. Cancer Research. 58: 5348-53. PMID 9850064  1
1998 Liang G, Salem CE, Yu MC, Nguyen HD, Gonzales FA, Nguyen TT, Nichols PW, Jones PA. DNA methylation differences associated with tumor tissues identified by genome scanning analysis. Genomics. 53: 260-8. PMID 9799591 DOI: 10.1006/geno.1998.5502  1
1998 Robertson KD, Jones PA. The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53. Molecular and Cellular Biology. 18: 6457-73. PMID 9774662  0.32
1998 Stein JP, Ginsberg DA, Grossfeld GD, Chatterjee SJ, Esrig D, Dickinson MG, Groshen S, Taylor CR, Jones PA, Skinner DG, Cote RJ. Effect of p21WAF1/CIP1 expression on tumor progression in bladder cancer. Journal of the National Cancer Institute. 90: 1072-9. PMID 9672255  0.44
1998 Gill PS, Tsai YC, Rao AP, Spruck CH, Zheng T, Harrington WA, Cheung T, Nathwani B, Jones PA. Evidence for multiclonality in multicentric Kaposi's sarcoma. Proceedings of the National Academy of Sciences of the United States of America. 95: 8257-61. PMID 9653174 DOI: 10.1073/pnas.95.14.8257  1
1998 Petrovich Z, Baert L, Boyd SD, Brady LW, D'Hallewin M, Heilmann HP, Jakse G, Jones PA, Van Der Meijden AP, Oyen RH, Van Poppel H, Rotman M, Sauer R, Shipley WU, Skinner EC. Management of carcinoma of the bladder. American Journal of Clinical Oncology. 21: 217-22. PMID 9626784 DOI: 10.1097/00000421-199806000-00001  1
1998 Jones PA, Gonzalgo ML, Tsutsumi M, Bender CM. DNA methylation in bladder cancer. European Urology. 33: 7-8. PMID 9615197  1
1998 Bender CM, Zingg JM, Jones PA. DNA methylation as a target for drug design. Pharmaceutical Research. 15: 175-87. PMID 9523301  0.48
1998 Gonzalgo ML, Hayashida T, Bender CM, Pao MM, Tsai YC, Gonzales FA, Nguyen HD, Nguyen TT, Jones PA. The role of DNA methylation in expression of the p19/p16 locus in human bladder cancer cell lines. Cancer Research. 58: 1245-52. PMID 9515812  1
1998 Bender CM, Pao MM, Jones PA. Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines. Cancer Research. 58: 95-101. PMID 9426064  1
1997 Robertson KD, Jones PA. Dynamic interrelationships between DNA replication, methylation, and repair. American Journal of Human Genetics. 61: 1220-4. PMID 9399916 DOI: 10.1086/301658  0.32
1997 Gonzalgo ML, Bender CM, You EH, Glendening JM, Flores JF, Walker GJ, Hayward NK, Jones PA, Fountain JW. Low frequency of p16/CDKN2A methylation in sporadic melanoma: comparative approaches for methylation analysis of primary tumors. Cancer Research. 57: 5336-47. PMID 9393758  0.48
1997 Kissil JL, Feinstein E, Cohen O, Jones PA, Tsai YC, Knowles MA, Eydmann ME, Kimchi A. DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene. Oncogene. 15: 403-7. PMID 9242376 DOI: 10.1038/sj.onc.1201172  1
1997 Van Tornout JM, Spruck CH, Shibata A, Schmutte C, Gonzalez-Zulueta M, Nichols PW, Chandrasoma PT, Yu MC, Jones PA. Presence of p53 mutations in primary nasopharyngeal carcinoma (NPC) in non-Asians of Los Angeles, California, a low-risk population for NPC. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 6: 493-7. PMID 9232335  0.6
1997 Gonzalgo ML, Liang G, Spruck CH, Zingg JM, Rideout WM, Jones PA. Identification and characterization of differentially methylated regions of genomic DNA by methylation-sensitive arbitrarily primed PCR. Cancer Research. 57: 594-9. PMID 9044832  1
1997 Cote RJ, Esrig D, Groshen S, Jones PA, Skinner DG. p53 and treatment of bladder cancer. Nature. 385: 123-5. PMID 8990112 DOI: 10.1038/385123b0  1
1996 Simoneau AR, Spruck CH, Gonzalez-Zulueta M, Gonzalgo ML, Chan MF, Tsai YC, Dean M, Steven K, Horn T, Jones PA. Evidence for two tumor suppressor loci associated with proximal chromosome 9p to q and distal chromosome 9q in bladder cancer and the initial screening for GAS1 and PTC mutations. Cancer Research. 56: 5039-43. PMID 8895761  0.72
1996 Zingg JM, Shen JC, Yang AS, Rapoport H, Jones PA. Methylation inhibitors can increase the rate of cytosine deamination by (cytosine-5)-DNA methyltransferase. Nucleic Acids Research. 24: 3267-75. PMID 8774911  1
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