William C. Wetsel, Ph.D. - Publications

Neurobiology Duke University, Durham, NC 
Behavioral neuroscience

188 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Martini ML, Ray C, Yu X, Liu J, Pogorelov VM, Wetsel WC, Huang XP, McCorvy JD, Caron MG, Jin J. Addition to "Designing Functionally Selective Noncatechol Dopamine D Receptor Agonists with Potent In Vivo Antiparkinsonian Activity". Acs Chemical Neuroscience. PMID 33830725 DOI: 10.1021/acschemneuro.1c00186  0.88
2020 Monroe TO, Garrett ME, Kousi M, Rodriguiz RM, Moon S, Bai Y, Brodar SC, Soldano KL, Savage J, Hansen TF, Muzny DM, Gibbs RA, Barak L, Sullivan PF, Ashley-Koch AE, ... ... Wetsel WC, et al. PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia. Nature Communications. 11: 5903. PMID 33214552 DOI: 10.1038/s41467-020-19637-5  0.68
2020 Yu S, Galeffi F, Rodriguiz RM, Wang Z, Shen Y, Lyu J, Li R, Bernstock JD, Johnson KR, Liu S, Sheng H, Turner DA, Wetsel WC, Paschen W, Yang W. Small ubiquitin-like modifier 2 (SUMO2) is critical for memory processes in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32910521 DOI: 10.1096/Fj.202000850Rr  0.68
2020 Slosky LM, Bai Y, Toth K, Ray C, Rochelle LK, Badea A, Chandrasekhar R, Pogorelov VM, Abraham DM, Atluri N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney P, Yuan H, ... ... Wetsel WC, et al. β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors. Cell. PMID 32470395 DOI: 10.1016/J.Cell.2020.04.053  0.88
2020 Wang P, Velagapudi R, Kong C, Rodriguiz RM, Wetsel WC, Yang T, Berger M, Gelbard HA, Colton CA, Terrando N. Neurovascular and immune mechanisms that regulate postoperative delirium superimposed on dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32291962 DOI: 10.1002/Alz.12064  0.68
2019 Velagapudi R, Subramaniyan S, Xiong C, Porkka F, Rodriguiz RM, Wetsel WC, Terrando N. Orthopedic Surgery Triggers Attention Deficits in a Delirium-Like Mouse Model. Frontiers in Immunology. 10: 2675. PMID 31911786 DOI: 10.3389/Fimmu.2019.02675  0.68
2019 Miller-Rhodes P, Kong C, Baht GS, Saminathan P, Rodriguiz RM, Wetsel WC, Gelbard HA, Terrando N. The broad spectrum mixed-lineage kinase 3 inhibitor URMC-099 prevents acute microgliosis and cognitive decline in a mouse model of perioperative neurocognitive disorders. Journal of Neuroinflammation. 16: 193. PMID 31660984 DOI: 10.1186/S12974-019-1582-5  0.68
2019 Martini ML, Ray C, Yu X, Liu J, Pogorelov V, Wetsel WC, Huang XP, McCorvy J, Caron MG, Jin J. Designing Functionally Selective Non-Catechol Dopamine D1 Receptor Agonists with Potent In Vivo Antiparkinsonian Activity. Acs Chemical Neuroscience. PMID 31387346 DOI: 10.1021/Acschemneuro.9B00410  0.88
2019 Pogorelov VM, Kao HT, Augustine GJ, Wetsel WC. Postsynaptic Mechanisms Render Syn I/II/III Mice Highly Responsive to Psychostimulants. The International Journal of Neuropsychopharmacology. PMID 31188434 DOI: 10.1093/Ijnp/Pyz019  0.56
2019 Shen Y, McCorvy JD, Martini ML, Rodriguiz RM, Pogorelov VM, Ward KM, Wetsel WC, Liu J, Roth BL, Jin J. D2 Dopamine Receptor G protein-biased Partial Agonists Based on Cariprazine. Journal of Medicinal Chemistry. PMID 30964661 DOI: 10.1021/Acs.Jmedchem.9B00508  0.68
2019 McGaughey KD, Yilmaz-Swenson T, Elsayed NM, Cruz DA, Rodriguiz RM, Kritzer MD, Peterchev AV, Roach J, Wetsel WC, Williamson DE. Relative abundance of Akkermansia spp. and other bacterial phylotypes correlates with anxiety- and depressive-like behavior following social defeat in mice. Scientific Reports. 9: 3281. PMID 30824791 DOI: 10.1038/S41598-019-40140-5  0.68
2018 Arbogast T, Razaz P, Ellegood J, McKinstry S, Erdin S, Currall B, Aneichyk T, Lerch JP, Qiu LR, Rodriguiz RM, Mark Henkelman R, Talkowski ME, Wetsel WC, Golzio C, Katsanis N. Kctd13-deficient mice display short-term memory impairment and sex-dependent genetic interactions. Human Molecular Genetics. PMID 30590535 DOI: 10.1093/Hmg/Ddy436  0.68
2018 Huffman WJ, Subramaniyan S, Rodriguiz RM, Wetsel WC, Grill WM, Terrando N. Modulation of neuroinflammation and memory dysfunction using percutaneous vagus nerve stimulation in mice. Brain Stimulation. PMID 30337243 DOI: 10.1016/J.Brs.2018.10.005  0.68
2018 Bey AL, Wang X, Yan H, Kim N, Passman RL, Yang Y, Cao X, Towers AJ, Hulbert SW, Duffney LJ, Gaidis E, Rodriguiz RM, Wetsel WC, Yin HH, Jiang YH. Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors. Translational Psychiatry. 8: 94. PMID 29700290 DOI: 10.1038/S41398-018-0142-6  0.68
2018 Martyn AC, Toth K, Schmalzigaug R, Hedrick NG, Rodriguiz RM, Yasuda R, Wetsel WC, Premont RT. GIT1 regulates synaptic structural plasticity underlying learning. Plos One. 13: e0194350. PMID 29554125 DOI: 10.1371/Journal.Pone.0194350  0.68
2017 Pappas AL, Bey AL, Wang X, Rossi M, Kim YH, Yan H, Porkka F, Duffney LJ, Phillips SM, Cao X, Ding JD, Rodriguiz RM, Yin HH, Weinberg RJ, Ji RR, ... Wetsel WC, et al. Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers. Jci Insight. 2. PMID 29046483 DOI: 10.1172/Jci.Insight.92052  0.68
2017 Butler RK, Ehling S, Barbar M, Thomas J, Hughes MA, Smith CE, Pogorelov VM, Aryal DK, Wetsel WC, Lascelles BDX. Distinct neuronal populations in the basolateral and central amygdala are activated with acute pain, conditioned fear, and fear-conditioned analgesia. Neuroscience Letters. PMID 28916300 DOI: 10.1016/J.Neulet.2017.09.025  0.72
2017 Berezniuk I, Rodriguiz RM, Zee ML, Marcus DJ, Pintar J, Morgan DJ, Wetsel WC, Fricker LD. ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine. Journal of Neurochemistry. PMID 28881029 DOI: 10.1111/Jnc.14209  0.68
2017 Wang X, Gallegos DA, Pogorelov VM, O'Hare JK, Calakos N, Wetsel WC, West AE. Parvalbumin Interneurons of the Mouse Nucleus Accumbens are Required for Amphetamine-Induced Locomotor Sensitization and Conditioned Place Preference. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28840858 DOI: 10.1038/Npp.2017.178  0.72
2017 Pogorelov VM, Rodriguiz RM, Cheng J, Huang M, Schmerberg CM, Meltzer HY, Roth BL, Kozikowski AP, Wetsel WC. 5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28294132 DOI: 10.1038/Npp.2017.52  0.68
2017 Cho KI, Yoon D, Qiu S, Danziger Z, Grill WM, Wetsel WC, Ferreira PA. Loss of Ranbp2 in motor neurons causes the disruption of nucleocytoplasmic and chemokine signaling and proteostasis of hnRNPH3 and Mmp28, and the development of amyotrophic lateral sclerosis (ALS)-like syndromes. Disease Models & Mechanisms. PMID 28100513 DOI: 10.1242/Dmm.027730  0.32
2016 Urs NM, Gee SM, Pack TF, McCorvy JD, Evron T, Snyder JC, Yang X, Rodriguiz RM, Borrelli E, Wetsel WC, Jin J, Roth BL, O'Donnell P, Caron MG. Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911814 DOI: 10.1073/Pnas.1614347113  0.88
2016 Ade KK, Wan Y, Hamann HC, O'Hare JK, Guo W, Quian A, Kumar S, Bhagat S, Rodriguiz RM, Wetsel WC, Conn PJ, Dzirasa K, Huber KM, Calakos N. Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice. Biological Psychiatry. PMID 27436084 DOI: 10.1016/J.Biopsych.2016.04.023  0.68
2016 Weitzel DH, Tovmasyan A, Ashcraft KA, Boico A, Birer SR, Roy Choudhury K, Herndon J, Rodriguiz RM, Wetsel WC, Peters KB, Spasojevic I, Batinic-Haberle I, Dewhirst MW. Neurobehavioral radiation mitigation to standard brain cancer therapy regimens by Mn(III) n-butoxyethylpyridylporphyrin-based redox modifier. Environmental and Molecular Mutagenesis. PMID 27224425 DOI: 10.1002/Em.22021  0.68
2016 Bhagat SL, Qiu S, Caffall ZF, Wan Y, Pan Y, Rodriquiz RM, Wetsel WC, Badea A, Hochgeschwender U, Calakos N. Mouse model of rare TOR1A variant found in sporadic focal dystonia impairs domains affected in DYT1 dystonia patients and animal models. Neurobiology of Disease. PMID 27168150 DOI: 10.1016/J.Nbd.2016.05.003  0.68
2016 Wang X, Bey AL, Katz BM, Badea A, Kim N, David LK, Duffney LJ, Kumar S, Mague SD, Hulbert SW, Dutta N, Hayrapetyan V, Yu C, Gaidis E, Zhao S, ... ... Wetsel WC, et al. Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism. Nature Communications. 7: 11459. PMID 27161151 DOI: 10.1038/Ncomms11459  0.68
2016 Barak LS, Bai Y, Peterson S, Evron T, Urs N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Chung TD, Rodriguiz RM, Wetsel WC, Thomas JB, Hanson GR, Pinkerton AB, et al. ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse. Acs Chemical Biology. PMID 27119457 DOI: 10.1021/Acschembio.6B00291  0.88
2016 Nagy E, Rodriguiz RM, Wetsel WC, MacIver NJ, Hale LP. Reproduction and Growth in a Murine Model of Early Life-Onset Inflammatory Bowel Disease. Plos One. 11: e0152764. PMID 27045690 DOI: 10.1371/Journal.Pone.0152764  0.68
2016 Farrell MS, McCorvy JD, Huang XP, Urban DJ, White KL, Giguere PM, Doak AK, Bernstein AI, Stout KA, Park SM, Rodriguiz RM, Gray BW, Hyatt WS, Norwood AP, Webster KA, ... ... Wetsel WC, et al. In Vitro and In Vivo Characterization of the Alkaloid Nuciferine. Plos One. 11: e0150602. PMID 26963248 DOI: 10.1371/Journal.Pone.0150602  0.68
2016 Matak P, Matak A, Moustafa S, Aryal DK, Benner EJ, Wetsel W, Andrews NC. Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929359 DOI: 10.1073/Pnas.1519473113  0.72
2016 Bao X, Chandramohan V, Reynolds RP, Norton JN, Wetsel WC, Rodriguiz RM, Aryal DK, McLendon RE, Levin ED, Petry NA, Zalutsky MR, Burnett BK, Kuan CT, Pastan IH, Bigner DD. Preclinical toxicity evaluation of a novel immunotoxin, D2C7-(scdsFv)-PE38KDEL, administered via intracerebral convection-enhanced delivery in rats. Investigational New Drugs. PMID 26728879 DOI: 10.1007/S10637-015-0318-3  0.72
2016 Wetsel W, Caron MG, Jin J, Park SM, Pogorelov VM, Rodriguiz RM, Schmerberg CM. PM435. Targeting Functional Selectivity of the Dopamine D2 Receptor for Treatment of Schizophrenia-like Behaviors The International Journal of Neuropsychopharmacology. 19: 58-58. DOI: 10.1093/Ijnp/Pyw041.435  0.88
2015 Klein RC, Acheson SK, Qadri LH, Dawson AA, Rodriguiz RM, Wetsel WC, Moore SD, Laskowitz DT, Dawson HN. Opposing effects of traumatic brain injury on excitatory synaptic function in the lateral amygdala in the absence and presence of preinjury stress. Journal of Neuroscience Research. PMID 26707710 DOI: 10.1002/Jnr.23702  0.68
2015 Cheng J, Giguère PM, Schmerberg CM, Pogorelov VM, Rodriguiz RM, Huang XP, Zhu H, McCorvy JD, Wetsel WC, Roth BL, Kozikowski AP. Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models. Journal of Medicinal Chemistry. PMID 26704965 DOI: 10.1021/Acs.Jmedchem.5B01153  0.68
2015 Scott JW, Park E, Rodriguiz RM, Oakhill JS, Issa SM, O'Brien MT, Dite TA, Langendorf CG, Wetsel WC, Means AR, Kemp BE. Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder. Scientific Reports. 5: 14436. PMID 26395653 DOI: 10.1038/Srep14436  1
2015 Urban DJ, Zhu H, Marcinkiewcz CA, Michaelides M, Oshibuchi H, Rhea D, Aryal DK, Farrell MS, Lowery-Gionta E, Olsen RH, Wetsel WC, Kash TL, Hurd YL, Tecott LH, Roth BL. Elucidation of the Behavioral Program and Neuronal Network Encoded by Dorsal Raphe Serotonergic Neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26383016 DOI: 10.1038/Npp.2015.293  0.72
2015 Park SM, Chen M, Schmerberg CM, Dulman RS, Rodriguiz RM, Caron MG, Jin J, Wetsel WC. Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-like Behavior in Hypoglutamatergic Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26129680 DOI: 10.1038/Npp.2015.196  1
2015 Kim IH, Rossi MA, Aryal DK, Racz B, Kim N, Uezu A, Wang F, Wetsel WC, Weinberg RJ, Yin H, Soderling SH. Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine. Nature Neuroscience. 18: 883-91. PMID 25938885 DOI: 10.1038/Nn.4015  1
2015 Cheng J, Giguère PM, Onajole OK, Lv W, Gaisin A, Gunosewoyo H, Schmerberg CM, Pogorelov VM, Rodriguiz RM, Vistoli G, Wetsel WC, Roth BL, Kozikowski AP. Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents. Journal of Medicinal Chemistry. 58: 1992-2002. PMID 25633969 DOI: 10.1021/Jm5019274  1
2015 Sachs BD, Rodriguiz RM, Tran HL, Iyer A, Wetsel WC, Caron MG. Serotonin deficiency alters susceptibility to the long-term consequences of adverse early life experience. Psychoneuroendocrinology. 53: 69-81. PMID 25602134 DOI: 10.1016/J.Psyneuen.2014.12.019  1
2015 Hunanyan AS, Fainberg NA, Linabarger M, Arehart E, Leonard AS, Adil SM, Helseth AR, Swearingen AK, Forbes SL, Rodriguiz RM, Rhodes T, Yao X, Kibbi N, Hochman DW, Wetsel WC, et al. Knock-in mouse model of alternating hemiplegia of childhood: behavioral and electrophysiologic characterization. Epilepsia. 56: 82-93. PMID 25523819 DOI: 10.1111/Epi.12878  1
2015 Cheng Y, Rodriguiz RM, Murthy SR, Senatorov V, Thouennon E, Cawley NX, Aryal DK, Ahn S, Lecka-Czernik B, Wetsel WC, Loh YP. Neurotrophic factor-α1 prevents stress-induced depression through enhancement of neurogenesis and is activated by rosiglitazone. Molecular Psychiatry. 20: 744-54. PMID 25330741 DOI: 10.1038/Mp.2014.136  1
2015 Weitzel DH, Tovmasyan A, Ashcraft KA, Rajic Z, Weitner T, Liu C, Li W, Buckley AF, Prasad MR, Young KH, Rodriguiz RM, Wetsel WC, Peters KB, Spasojevic I, Herndon JE, et al. Radioprotection of the brain white matter by Mn(III) n-Butoxyethylpyridylporphyrin-based superoxide dismutase mimic MnTnBuOE-2-PyP5+. Molecular Cancer Therapeutics. 14: 70-9. PMID 25319393 DOI: 10.1158/1535-7163.Mct-14-0343  1
2014 Wu CL, Jain D, McNeill JN, Little D, Anderson JA, Huebner JL, Kraus VB, Rodriguiz RM, Wetsel WC, Guilak F. Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury. Annals of the Rheumatic Diseases. PMID 25015373 DOI: 10.1136/Annrheumdis-2014-205601  1
2014 Wang L, Rodriguiz RM, Wetsel WC, Sheng H, Zhao S, Liu X, Paschen W, Yang W. Neuron-specific Sumo1-3 knockdown in mice impairs episodic and fear memories. Journal of Psychiatry & Neuroscience : Jpn. 39: 259-66. PMID 24690371 DOI: 10.1503/Jpn.130148  1
2014 Deng JV, Wan Y, Wang X, Cohen S, Wetsel WC, Greenberg ME, Kenny PJ, Calakos N, West AE. MeCP2 phosphorylation limits psychostimulant-induced behavioral and neuronal plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4519-27. PMID 24671997 DOI: 10.1523/Jneurosci.2821-13.2014  1
2014 Gaier ED, Rodriguiz RM, Zhou J, Ralle M, Wetsel WC, Eipper BA, Mains RE. In vivo and in vitro analyses of amygdalar function reveal a role for copper. Journal of Neurophysiology. 111: 1927-39. PMID 24554785 DOI: 10.1152/Jn.00631.2013  1
2013 Ruzzo EK, Capo-Chichi JM, Ben-Zeev B, Chitayat D, Mao H, Pappas AL, Hitomi Y, Lu YF, Yao X, Hamdan FF, Pelak K, Reznik-Wolf H, Bar-Joseph I, Oz-Levi D, Lev D, ... ... Wetsel WC, et al. Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy. Neuron. 80: 429-41. PMID 24139043 DOI: 10.1016/J.Neuron.2013.08.013  1
2013 Wetsel WC, Rodriguiz RM, Guillemot J, Rousselet E, Essalmani R, Kim IH, Bryant JC, Marcinkiewicz J, Desjardins R, Day R, Constam DB, Prat A, Seidah NG. Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 17362-7. PMID 24101515 DOI: 10.1073/Pnas.1314698110  1
2013 Gomes I, Aryal DK, Wardman JH, Gupta A, Gagnidze K, Rodriguiz RM, Kumar S, Wetsel WC, Pintar JE, Fricker LD, Devi LA. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proceedings of the National Academy of Sciences of the United States of America. 110: 16211-6. PMID 24043826 DOI: 10.1073/Pnas.1312938110  1
2013 Gaier ED, Miller MB, Ralle M, Aryal D, Wetsel WC, Mains RE, Eipper BA. Peptidylglycine α-amidating monooxygenase heterozygosity alters brain copper handling with region specificity. Journal of Neurochemistry. 127: 605-19. PMID 24032518 DOI: 10.1111/Jnc.12438  1
2013 Liu G, Gu B, He XP, Joshi RB, Wackerle HD, Rodriguiz RM, Wetsel WC, McNamara JO. Transient inhibition of TrkB kinase after status epilepticus prevents development of temporal lobe epilepsy. Neuron. 79: 31-8. PMID 23790754 DOI: 10.1016/J.Neuron.2013.04.027  1
2013 Sachs BD, Rodriguiz RM, Siesser WB, Kenan A, Royer EL, Jacobsen JP, Wetsel WC, Caron MG. The effects of brain serotonin deficiency on behavioural disinhibition and anxiety-like behaviour following mild early life stress. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 2081-94. PMID 23672796 DOI: 10.1017/S1461145713000321  1
2013 Kim IH, Racz B, Wang H, Burianek L, Weinberg R, Yasuda R, Wetsel WC, Soderling SH. Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6081-92. PMID 23554489 DOI: 10.1523/Jneurosci.0035-13.2013  1
2013 Rodriguiz RM, Wilkins JJ, Creson TK, Biswas R, Berezniuk I, Fricker AD, Fricker LD, Wetsel WC. Emergence of anxiety-like behaviours in depressive-like Cpe(fat/fat) mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1623-34. PMID 23442571 DOI: 10.1017/S1461145713000059  1
2013 Sassano MF, Allen JA, Jin J, Setola V, Wetsel WC, Caron MG, Roth BL. D2 Functionally Selective Ligands: Novel Therapeutics? Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 105. DOI: 10.1016/B978-0-12-800044-1.00091-X  1
2013 Wetsel WC, Moy SS, Jiang YH. Mouse Behavioral Models for Autism Spectrum Disorders The Neuroscience of Autism Spectrum Disorders. 363-378. DOI: 10.1016/B978-0-12-391924-3.00026-0  1
2012 Wong P, Chang CC, Marx CE, Caron MG, Wetsel WC, Zhang X. Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice. Plos One. 7: e51455. PMID 23240026 DOI: 10.1371/Journal.Pone.0051455  1
2012 Besnard J, Ruda GF, Setola V, Abecassis K, Rodriguiz RM, Huang XP, Norval S, Sassano MF, Shin AI, Webster LA, Simeons FR, Stojanovski L, Prat A, Seidah NG, Constam DB, ... ... Wetsel WC, et al. Automated design of ligands to polypharmacological profiles. Nature. 492: 215-20. PMID 23235874 DOI: 10.1038/Nature11691  1
2012 Por ED, Bierbower SM, Berg KA, Gomez R, Akopian AN, Wetsel WC, Jeske NA. β-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel. The Journal of Biological Chemistry. 287: 37552-63. PMID 22952227 DOI: 10.1074/Jbc.M112.391847  1
2012 Chen X, Sassano MF, Zheng L, Setola V, Chen M, Bai X, Frye SV, Wetsel WC, Roth BL, Jin J. Structure-functional selectivity relationship studies of β-arrestin-biased dopamine Dâ‚‚ receptor agonists. Journal of Medicinal Chemistry. 55: 7141-53. PMID 22845053 DOI: 10.1021/Jm300603Y  1
2012 Cawley NX, Wetsel WC, Murthy SR, Park JJ, Pacak K, Loh YP. New roles of carboxypeptidase E in endocrine and neural function and cancer. Endocrine Reviews. 33: 216-53. PMID 22402194 DOI: 10.1210/Er.2011-1039  1
2012 Lee TH, Szabo ST, Fowler JC, Mannelli P, Mangum OB, Beyer WF, Patkar A, Wetsel WC. Pharmacologically-mediated reactivation and reconsolidation blockade of the psychostimulant-abuse circuit: a novel treatment strategy. Drug and Alcohol Dependence. 124: 11-8. PMID 22356892 DOI: 10.1016/J.Drugalcdep.2012.01.021  1
2012 Fukada M, Hanai A, Nakayama A, Suzuki T, Miyata N, Rodriguiz RM, Wetsel WC, Yao TP, Kawaguchi Y. Loss of deacetylation activity of Hdac6 affects emotional behavior in mice. Plos One. 7: e30924. PMID 22328923 DOI: 10.1371/Journal.Pone.0030924  1
2012 Hutchinson AN, Deng JV, Aryal DK, Wetsel WC, West AE. Differential regulation of MeCP2 phosphorylation in the CNS by dopamine and serotonin. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 321-37. PMID 21956448 DOI: 10.1038/Npp.2011.190  1
2011 Daigle TL, Wetsel WC, Caron MG. Opposite function of dopamine D1 and N-methyl-D-aspartate receptors in striatal cannabinoid-mediated signaling. The European Journal of Neuroscience. 34: 1378-89. PMID 22034973 DOI: 10.1111/J.1460-9568.2011.07874.X  1
2011 Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, et al. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proceedings of the National Academy of Sciences of the United States of America. 108: 18488-93. PMID 22025698 DOI: 10.1073/Pnas.1104807108  1
2011 Cohen S, Gabel HW, Hemberg M, Hutchinson AN, Sadacca LA, Ebert DH, Harmin DA, Greenberg RS, Verdine VK, Zhou Z, Wetsel WC, West AE, Greenberg ME. Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function. Neuron. 72: 72-85. PMID 21982370 DOI: 10.1016/J.Neuron.2011.08.022  1
2011 Miller LK, Hou X, Rodriguiz RM, Gagnidze K, Sweedler JV, Wetsel WC, Devi LA. Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord. Journal of Neurochemistry. 119: 1074-85. PMID 21972895 DOI: 10.1111/J.1471-4159.2011.07513.X  0.68
2011 Porton B, Wetsel WC, Kao HT. Synapsin III: role in neuronal plasticity and disease. Seminars in Cell & Developmental Biology. 22: 416-24. PMID 21827867 DOI: 10.1016/J.Semcdb.2011.07.007  1
2011 Rodriguiz RM, Colvin JS, Wetsel WC. Neurophenotyping genetically modified mice for social behavior. Methods in Molecular Biology (Clifton, N.J.). 768: 343-63. PMID 21805253 DOI: 10.1007/978-1-61779-204-5_19  1
2011 Wetsel WC. Sensing hot and cold with TRP channels. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 27: 388-98. PMID 21591901 DOI: 10.3109/02656736.2011.554337  1
2011 Wetsel WC. Hyperthermic effects on behavior. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 27: 353-73. PMID 21591899 DOI: 10.3109/02656736.2010.550905  1
2011 Bhatia KS, Szabo ST, Fowler JC, Wetsel WC, Lee TH. Reversal of long-term methamphetamine sensitization by combination of pergolide with ondansetron or ketanserin, but not mirtazapine. Behavioural Brain Research. 223: 227-32. PMID 21571009 DOI: 10.1016/J.Bbr.2011.04.045  1
2011 Wang X, McCoy PA, Rodriguiz RM, Pan Y, Je HS, Roberts AC, Kim CJ, Berrios J, Colvin JS, Bousquet-Moore D, Lorenzo I, Wu G, Weinberg RJ, Ehlers MD, Philpot BD, ... ... Wetsel WC, et al. Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3. Human Molecular Genetics. 20: 3093-108. PMID 21558424 DOI: 10.1093/Hmg/Ddr212  1
2011 Carlson BR, Lloyd KE, Kruszewski A, Kim IH, Rodriguiz RM, Heindel C, Faytell M, Dudek SM, Wetsel WC, Soderling SH. WRP/srGAP3 facilitates the initiation of spine development by an inverse F-BAR domain, and its loss impairs long-term memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2447-60. PMID 21325512 DOI: 10.1523/Jneurosci.4433-10.2011  1
2010 Gaier ED, Rodriguiz RM, Ma XM, Sivaramakrishnan S, Bousquet-Moore D, Wetsel WC, Eipper BA, Mains RE. Haploinsufficiency in peptidylglycine alpha-amidating monooxygenase leads to altered synaptic transmission in the amygdala and impaired emotional responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13656-69. PMID 20943906 DOI: 10.1523/Jneurosci.2200-10.2010  1
2010 Deng JV, Rodriguiz RM, Hutchinson AN, Kim IH, Wetsel WC, West AE. MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants. Nature Neuroscience. 13: 1128-36. PMID 20711186 DOI: 10.1038/Nn.2614  1
2010 Kile BM, Guillot TS, Venton BJ, Wetsel WC, Augustine GJ, Wightman RM. Synapsins differentially control dopamine and serotonin release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9762-70. PMID 20660258 DOI: 10.1523/Jneurosci.2071-09.2010  1
2010 Griffin TM, Fermor B, Huebner JL, Kraus VB, Rodriguiz RM, Wetsel WC, Cao L, Setton LA, Guilak F. Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice. Arthritis Research & Therapy. 12: R130. PMID 20604941 DOI: 10.1186/Ar3068  1
2010 McDowell KA, Hutchinson AN, Wong-Goodrich SJ, Presby MM, Su D, Rodriguiz RM, Law KC, Williams CL, Wetsel WC, West AE. Reduced cortical BDNF expression and aberrant memory in Carf knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7453-65. PMID 20519520 DOI: 10.1523/Jneurosci.3997-09.2010  1
2010 Crooks KR, Kleven DT, Rodriguiz RM, Wetsel WC, McNamara JO. TrkB signaling is required for behavioral sensitization and conditioned place preference induced by a single injection of cocaine. Neuropharmacology. 58: 1067-77. PMID 20176040 DOI: 10.1016/J.Neuropharm.2010.01.014  1
2010 Porton B, Rodriguiz RM, Phillips LE, Gilbert JW, Feng J, Greengard P, Kao HT, Wetsel WC. Mice lacking synapsin III show abnormalities in explicit memory and conditioned fear. Genes, Brain, and Behavior. 9: 257-68. PMID 20050925 DOI: 10.1111/J.1601-183X.2009.00555.X  1
2010 Bousquet-Moore D, Prohaska JR, Nillni EA, Czyzyk T, Wetsel WC, Mains RE, Eipper BA. Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. Neurobiology of Disease. 37: 130-40. PMID 19815072 DOI: 10.1016/J.Nbd.2009.09.016  1
2010 Chen Q, Zhu X, Zhang Y, Wetsel WC, Lee TH, Zhang X. Integrin-linked kinase is involved in cocaine sensitization by regulating PSD-95 and synapsin I expression and GluR1 Ser845 phosphorylation. Journal of Molecular Neuroscience : Mn. 40: 284-94. PMID 19629758 DOI: 10.1007/S12031-009-9218-3  1
2009 Allen KD, Griffin TM, Rodriguiz RM, Wetsel WC, Kraus VB, Huebner JL, Boyd LM, Setton LA. Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen. Arthritis and Rheumatism. 60: 2684-93. PMID 19714629 DOI: 10.1002/Art.24783  1
2009 Roberts AC, Díez-García J, Rodriguiz RM, López IP, Luján R, Martínez-Turrillas R, Picó E, Henson MA, Bernardo DR, Jarrett TM, Clendeninn DJ, López-Mascaraque L, Feng G, Lo DC, Wesseling JF, ... Wetsel WC, et al. Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation. Neuron. 63: 342-56. PMID 19679074 DOI: 10.1016/J.Neuron.2009.06.016  1
2009 Yuan L, Seo JS, Kang NS, Keinan S, Steele SE, Michelotti GA, Wetsel WC, Beratan DN, Gong YD, Lee TH, Hong J. Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse. Molecular Biosystems. 5: 927-30. PMID 19668856 DOI: 10.1039/B903036K  1
2009 Yan F, Bikbulatov RV, Mocanu V, Dicheva N, Parker CE, Wetsel WC, Mosier PD, Westkaemper RB, Allen JA, Zjawiony JK, Roth BL. Structure-based design, synthesis, and biochemical and pharmacological characterization of novel salvinorin A analogues as active state probes of the kappa-opioid receptor. Biochemistry. 48: 6898-908. PMID 19555087 DOI: 10.1021/Bi900605N  1
2009 Nehrenberg DL, Rodriguiz RM, Cyr M, Zhang X, Lauder JM, Gariépy JL, Wetsel WC. An anxiety-like phenotype in mice selectively bred for aggression. Behavioural Brain Research. 201: 179-91. PMID 19428632 DOI: 10.1016/J.Bbr.2009.02.010  1
2009 Schmalzigaug R, Rodriguiz RM, Bonner PE, Davidson CE, Wetsel WC, Premont RT. Impaired fear response in mice lacking GIT1. Neuroscience Letters. 458: 79-83. PMID 19383529 DOI: 10.1016/J.Neulet.2009.04.037  1
2009 Schmalzigaug R, Rodriguiz RM, Phillips LE, Davidson CE, Wetsel WC, Premont RT. Anxiety-like behaviors in mice lacking GIT2. Neuroscience Letters. 451: 156-61. PMID 19114090 DOI: 10.1016/J.Neulet.2008.12.034  1
2009 Liu Y, Sun QA, Chen Q, Lee TH, Huang Y, Wetsel WC, Michelotti GA, Sullenger BA, Zhang X. Targeting inhibition of GluR1 Ser845 phosphorylation with an RNA aptamer that blocks AMPA receptor trafficking. Journal of Neurochemistry. 108: 147-57. PMID 19046328 DOI: 10.1111/J.1471-4159.2008.05748.X  1
2008 Rodriguiz RM, Gadnidze K, Ragnauth A, Dorr N, Yanagisawa M, Wetsel WC, Devi LA. Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory. Genes, Brain, and Behavior. 7: 418-26. PMID 21450041 DOI: 10.1111/J.1601-183X.2007.00365.X  1
2008 Chen Q, Xiong X, Lee TH, Liu Y, Wetsel WC, Zhang X. Neural plasticity and addiction: integrin-linked kinase and cocaine behavioral sensitization. Journal of Neurochemistry. 107: 679-89. PMID 18702665 DOI: 10.1111/J.1471-4159.2008.05619.X  1
2008 Ream MA, Chandra R, Peavey M, Ray AM, Roffler-Tarlov S, Kim HG, Wetsel WC, Rockman HA, Chikaraishi DM. High oxygen prevents fetal lethality due to lack of catecholamines. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R942-53. PMID 18635452 DOI: 10.1152/Ajpregu.00860.2007  1
2008 Taylor GA, Rodriguiz RM, Greene RI, Daniell X, Henry SC, Crooks KR, Kotloski R, Tessarollo L, Phillips LE, Wetsel WC. Behavioral characterization of P311 knockout mice. Genes, Brain, and Behavior. 7: 786-95. PMID 18616608 DOI: 10.1111/J.1601-183X.2008.00420.X  1
2008 Chen Q, Xiong X, Lee TH, Liu Y, Sun QA, Wetsel W, Zhang X. Adeno-associated virus-mediated ILK gene silencing in the rat NAc core. Journal of Neuroscience Methods. 173: 208-14. PMID 18602949 DOI: 10.1016/J.Jneumeth.2008.06.004  1
2008 Woronowicz A, Koshimizu H, Chang SY, Cawley NX, Hill JM, Rodriguiz RM, Abebe D, Dorfman C, Senatorov V, Zhou A, Xiong ZG, Wetsel WC, Loh YP. Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits. Hippocampus. 18: 1051-63. PMID 18570185 DOI: 10.1002/Hipo.20462  1
2008 Beaulieu JM, Zhang X, Rodriguiz RM, Sotnikova TD, Cools MJ, Wetsel WC, Gainetdinov RR, Caron MG. Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency. Proceedings of the National Academy of Sciences of the United States of America. 105: 1333-8. PMID 18212115 DOI: 10.1073/Pnas.0711496105  1
2008 Beaulieu JM, Marion S, Rodriguiz RM, Medvedev IO, Sotnikova TD, Ghisi V, Wetsel WC, Lefkowitz RJ, Gainetdinov RR, Caron MG. A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell. 132: 125-36. PMID 18191226 DOI: 10.1016/J.Cell.2007.11.041  1
2008 Jensen NH, Rodriguiz RM, Caron MG, Wetsel WC, Rothman RB, Roth BL. N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2303-12. PMID 18059438 DOI: 10.1038/Sj.Npp.1301646  1
2008 Beaulieu JM, Zhang X, Rodriguiz RM, Sotnikova TD, Wetsel WC, Gainetdinov RR, Caron MG. Reply to Belmaker et al.: GSK3β haploinsufficiency results in lithium-like effects in the forced-swim test Proceedings of the National Academy of Sciences of the United States of America. 105: E24. DOI: 10.1073/Pnas.0803026105  1
2007 Fukui M, Rodriguiz RM, Zhou J, Jiang SX, Phillips LE, Caron MG, Wetsel WC. Vmat2 heterozygous mutant mice display a depressive-like phenotype. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10520-9. PMID 17898223 DOI: 10.1523/Jneurosci.4388-06.2007  1
2007 Welch JM, Lu J, Rodriguiz RM, Trotta NC, Peca J, Ding JD, Feliciano C, Chen M, Adams JP, Luo J, Dudek SM, Weinberg RJ, Calakos N, Wetsel WC, Feng G. Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice. Nature. 448: 894-900. PMID 17713528 DOI: 10.1038/Nature06104  1
2007 Porton B, Wetsel WC. Reduction of synapsin III in the prefrontal cortex of individuals with schizophrenia. Schizophrenia Research. 94: 366-70. PMID 17540541 DOI: 10.1016/J.Schres.2007.04.016  1
2007 Chen Q, Lee TH, Wetsel WC, Sun QA, Liu Y, Davidson C, Xiong X, Ellinwood EH, Zhang X. Reversal of cocaine sensitization-induced behavioral sensitization normalizes GAD67 and GABAA receptor alpha2 subunit expression, and PKC zeta activity. Biochemical and Biophysical Research Communications. 356: 733-8. PMID 17382295 DOI: 10.1016/J.Bbrc.2007.03.041  1
2007 Badea A, Nicholls PJ, Johnson GA, Wetsel WC. Neuroanatomical phenotypes in the reeler mouse. Neuroimage. 34: 1363-74. PMID 17185001 DOI: 10.1016/J.Neuroimage.2006.09.053  1
2007 Zhang X, Lee TH, Davidson C, Lazarus C, Wetsel WC, Ellinwood EH. Reversal of cocaine-induced behavioral sensitization and associated phosphorylation of the NR2B and GluR1 subunits of the NMDA and AMPA receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 377-87. PMID 16794574 DOI: 10.1038/Sj.Npp.1301101  1
2006 Zhang X, Lee TH, Xiong X, Chen Q, Davidson C, Wetsel WC, Ellinwood EH. Methamphetamine induces long-term changes in GABAA receptor alpha2 subunit and GAD67 expression. Biochemical and Biophysical Research Communications. 351: 300-5. PMID 17056007 DOI: 10.1016/J.Bbrc.2006.10.046  1
2006 Prado VF, Martins-Silva C, de Castro BM, Lima RF, Barros DM, Amaral E, Ramsey AJ, Sotnikova TD, Ramirez MR, Kim HG, Rossato JI, Koenen J, Quan H, Cota VR, Moraes MF, ... ... Wetsel WC, et al. Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition. Neuron. 51: 601-12. PMID 16950158 DOI: 10.1016/J.Neuron.2006.08.005  1
2006 Venton BJ, Seipel AT, Phillips PE, Wetsel WC, Gitler D, Greengard P, Augustine GJ, Wightman RM. Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3206-9. PMID 16554471 DOI: 10.1523/Jneurosci.4901-04.2006  1
2006 Zhang X, Mi J, Wetsel WC, Davidson C, Xiong X, Chen Q, Ellinwood EH, Lee TH. PI3 kinase is involved in cocaine behavioral sensitization and its reversal with brain area specificity. Biochemical and Biophysical Research Communications. 340: 1144-50. PMID 16414349 DOI: 10.1016/J.Bbrc.2005.12.114  1
2005 Sotnikova TD, Beaulieu JM, Barak LS, Wetsel WC, Caron MG, Gainetdinov RR. Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. Plos Biology. 3: e271. PMID 16050778 DOI: 10.1371/Journal.Pbio.0030271  1
2005 Gammon CM, Freeman GM, Xie W, Xie W, Petersen SL, Wetsel WC. Regulation of gonadotropin-releasing hormone secretion by cannabinoids. Endocrinology. 146: 4491-9. PMID 16020480 DOI: 10.1210/En.2004-1672  1
2005 Pillai-Nair N, Panicker AK, Rodriguiz RM, Gilmore KL, Demyanenko GP, Huang JZ, Wetsel WC, Maness PF. Neural cell adhesion molecule-secreting transgenic mice display abnormalities in GABAergic interneurons and alterations in behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4659-71. PMID 15872114 DOI: 10.1523/Jneurosci.0565-05.2005  1
2005 Jacobsen JP, Rodriguiz RM, Mørk A, Wetsel WC. Monoaminergic dysregulation in glutathione-deficient mice: possible relevance to schizophrenia? Neuroscience. 132: 1055-72. PMID 15857710 DOI: 10.1016/J.Neuroscience.2005.01.059  1
2005 Pogorelov VM, Rodriguiz RM, Insco ML, Caron MG, Wetsel WC. Novelty seeking and stereotypic activation of behavior in mice with disruption of the Dat1 gene. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1818-31. PMID 15856082 DOI: 10.1038/Sj.Npp.1300724  1
2004 Gitler D, Takagishi Y, Feng J, Ren Y, Rodriguiz RM, Wetsel WC, Greengard P, Augustine GJ. Different presynaptic roles of synapsins at excitatory and inhibitory synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11368-80. PMID 15601943 DOI: 10.1523/Jneurosci.3795-04.2004  1
2004 Grove M, Demyanenko G, Echarri A, Zipfel PA, Quiroz ME, Rodriguiz RM, Playford M, Martensen SA, Robinson MR, Wetsel WC, Maness PF, Pendergast AM. ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. Molecular and Cellular Biology. 24: 10905-22. PMID 15572692 DOI: 10.1128/Mcb.24.24.10905-10922.2004  1
2004 Cawley NX, Zhou J, Hill JM, Abebe D, Romboz S, Yanik T, Rodriguiz RM, Wetsel WC, Loh YP. The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits. Endocrinology. 145: 5807-19. PMID 15358678 DOI: 10.1210/En.2004-0847  1
2004 Quan H, Athirakul K, Wetsel WC, Torres GE, Stevens R, Chen YT, Coffman TM, Caron MG. Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2. Molecular and Cellular Biology. 24: 4166-73. PMID 15121838 DOI: 10.1128/Mcb.24.10.4166-4173.2004  1
2004 Longo M, Brama M, Marino M, Bernardini S, Korach KS, Wetsel WC, Scandurra R, Faraggiana T, Spera G, Baron R, Teti A, Migliaccio S. Interaction of estrogen receptor alpha with protein kinase C alpha and c-Src in osteoblasts during differentiation. Bone. 34: 100-11. PMID 14751567 DOI: 10.1016/J.Bone.2003.09.007  1
2004 Srinivasan S, Bunch DO, Feng Y, Rodriguiz RM, Li M, Ravenell RL, Luo GX, Arimura A, Fricker LD, Eddy EM, Wetsel WC. Deficits in reproduction and pro-gonadotropin-releasing hormone processing in male Cpefat mice. Endocrinology. 145: 2023-34. PMID 14715715 DOI: 10.1210/En.2003-1442  1
2004 Rodriguiz RM, Chu R, Caron MG, Wetsel WC. Aberrant responses in social interaction of dopamine transporter knockout mice. Behavioural Brain Research. 148: 185-98. PMID 14684259 DOI: 10.1016/S0166-4328(03)00187-6  1
2003 Trinh JV, Nehrenberg DL, Jacobsen JP, Caron MG, Wetsel WC. Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice. Neuroscience. 118: 297-310. PMID 12699766 DOI: 10.1016/S0306-4522(03)00165-9  1
2002 Wetsel WC, Srinivasan S. Pro-GnRH processing. Progress in Brain Research. 141: 221-41. PMID 12512470 DOI: 10.1016/S0079-6123(02)41096-5  1
2002 Nillni EA, Xie W, Mulcahy L, Sanchez VC, Wetsel WC. Deficiencies in pro-thyrotropin-releasing hormone processing and abnormalities in thermoregulation in Cpefat/fat mice. The Journal of Biological Chemistry. 277: 48587-95. PMID 12270926 DOI: 10.1074/Jbc.M206702200  1
2002 Haller J, Bakos N, Rodriguiz RM, Caron MG, Wetsel WC, Liposits Z. Behavioral responses to social stress in noradrenaline transporter knockout mice: effects on social behavior and depression. Brain Research Bulletin. 58: 279-84. PMID 12128153 DOI: 10.1016/S0361-9230(02)00789-X  1
2001 Kreda SM, Sumner M, Fillo S, Ribeiro CM, Luo GX, Xie W, Daniel KW, Shears S, Collins S, Wetsel WC. alpha(1)-adrenergic receptors mediate LH-releasing hormone secretion through phospholipases C and A(2) in immortalized hypothalamic neurons. Endocrinology. 142: 4839-51. PMID 11606452 DOI: 10.1210/Endo.142.11.8506  1
2000 Ribar TJ, Rodriguiz RM, Khiroug L, Wetsel WC, Augustine GJ, Means AR. Cerebellar defects in Ca2+/calmodulin kinase IV-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC107. PMID 11069976 DOI: 10.1523/Jneurosci.20-22-J0004.2000  1
2000 Jeohn GH, Wilson B, Wetsel WC, Hong JS. The indolocarbazole Gö6976 protects neurons from lipopolysaccharide/interferon-gamma-induced cytotoxicity in murine neuron/glia co-cultures. Brain Research. Molecular Brain Research. 79: 32-44. PMID 10925141 DOI: 10.1016/S0169-328X(00)00082-6  1
2000 Jeohn GH, Chang RC, Kim WG, Wilson B, Mohney RP, Wetsel WC, Hong JS. Post-transcriptional inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase by Gö6976 in murine microglia. Brain Research. Molecular Brain Research. 79: 18-31. PMID 10925140 DOI: 10.1016/S0169-328X(00)00081-4  1
2000 Xu F, Gainetdinov RR, Wetsel WC, Jones SR, Bohn LM, Miller GW, Wang YM, Caron MG. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. Nature Neuroscience. 3: 465-71. PMID 10769386 DOI: 10.1038/74839  1
2000 Sarkis EH, Gainetdinov RR, Wetsel WC, Caron MG. 'Model' behavior [4] (multiple letters) Science. 287: 2160-2162. PMID 10744536  1
1999 Davis BJ, Lennard DE, Lee CA, Tiano HF, Morham SG, Wetsel WC, Langenbach R. Anovulation in cyclooxygenase-2-deficient mice is restored by prostaglandin E2 and interleukin-1beta. Endocrinology. 140: 2685-95. PMID 10342859 DOI: 10.1210/Endo.140.6.6715  1
1999 Isaac RE, Michaud A, Keen JN, Williams TA, Coates D, Wetsel WC, Corvol P. Hydrolysis by somatic angiotensin-I converting enzyme of basic dipeptides from a cholecystokinin/gastrin and a LH-RH peptide extended at the C-terminus with gly-Arg/Lys-arg, but not from diarginyl insulin. European Journal of Biochemistry / Febs. 262: 569-74. PMID 10336644 DOI: 10.1046/J.1432-1327.1999.00419.X  1
1999 Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG. Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science (New York, N.Y.). 283: 397-401. PMID 9888856 DOI: 10.1126/Science.283.5400.397  1
1998 Migliaccio S, Washburn TF, Fillo S, Rivera H, Teti A, Korach KS, Wetsel WC. Modulation of estrogen receptor levels in mouse uterus by protein kinase C isoenzymes. Endocrinology. 139: 4598-606. PMID 9794471 DOI: 10.1210/Endo.139.11.6300  1
1998 Lindzey J, Wetsel WC, Couse JF, Stoker T, Cooper R, Korach KS. Effects of castration and chronic steroid treatments on hypothalamic gonadotropin-releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-alpha knockout mice. Endocrinology. 139: 4092-101. PMID 9751487 DOI: 10.1210/Endo.139.10.6253  1
1998 Migliaccio S, Bernardini S, Wetsel WC, Korach KS, Faraggiana T, Teti A. Protein kinase C modulates estrogen receptors in differentiated osteoblastic cells in vitro. Steroids. 63: 352-4. PMID 9618801 DOI: 10.1016/S0039-128X(98)00040-3  1
1997 Colombo PJ, Wetsel WC, Gallagher M. Spatial memory is related to hippocampal subcellular concentrations of calcium-dependent protein kinase C isoforms in young and aged rats. Proceedings of the National Academy of Sciences of the United States of America. 94: 14195-9. PMID 9391176 DOI: 10.1073/Pnas.94.25.14195  1
1997 Caron KM, Soo SC, Wetsel WC, Stocco DM, Clark BJ, Parker KL. Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia. Proceedings of the National Academy of Sciences of the United States of America. 94: 11540-5. PMID 9326645 DOI: 10.1073/Pnas.94.21.11540  1
1997 Bossé R, Fumagalli F, Jaber M, Giros B, Gainetdinov RR, Wetsel WC, Missale C, Caron MG. Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. Neuron. 19: 127-38. PMID 9247269 DOI: 10.1016/S0896-6273(00)80353-0  1
1997 Ma YJ, Berg-von der Emde K, Rage F, Wetsel WC, Ojeda SR. Hypothalamic astrocytes respond to transforming growth factor-alpha with the secretion of neuroactive substances that stimulate the release of luteinizing hormone-releasing hormone. Endocrinology. 138: 19-25. PMID 8977380 DOI: 10.1210/endo.138.1.4863  1
1996 Zappelli F, Willems D, Osada S, Ohno S, Wetsel WC, Molinaro M, Cossu G, Bouché M. The inhibition of differentiation caused by TGFbeta in fetal myoblasts is dependent upon selective expression of PKCtheta: a possible molecular basis for myoblast diversification during limb histogenesis. Developmental Biology. 180: 156-64. PMID 8948582 DOI: 10.1006/Dbio.1996.0292  1
1996 Pascale A, Fortino I, Govoni S, Trabucchi M, Wetsel WC, Battaini F. Functional impairment in protein kinase C by RACK1 (receptor for activated C kinase 1) deficiency in aged rat brain cortex. Journal of Neurochemistry. 67: 2471-7. PMID 8931480 DOI: 10.1046/J.1471-4159.1996.67062471.X  1
1996 Pascale A, Fortino I, Govoni S, Trabucchi M, Wetsel WC, Battaini F. Differential isoform-specific regulation of calcium-independent protein kinase C in rat cerebral cortex. Neuroscience Letters. 214: 99-102. PMID 8878093 DOI: 10.1016/0304-3940(96)12901-3  1
1996 Wetsel WC, Hill DF, Ojeda SR. Basic fibroblast growth factor regulates the conversion of pro-luteinizing hormone-releasing hormone (Pro-LHRH) to LHRH in immortalized hypothalamic neurons. Endocrinology. 137: 2606-16. PMID 8641215 DOI: 10.1210/Endo.137.6.8641215  1
1996 Voigt P, Ma YJ, Gonzalez D, Fahrenbach WH, Wetsel WC, Berg-von der Emde K, Hill DF, Taylor KG, Costa ME, Seidah NG, Ojeda SR. Neural and glial-mediated effects of growth factors acting via tyrosine kinase receptors on luteinizing hormone-releasing hormone neurons. Endocrinology. 137: 2593-605. PMID 8641214 DOI: 10.1210/Endo.137.6.8641214  1
1996 Belsham DD, Wetsel WC, Mellon PL. NMDA and nitric oxide act through the cGMP signal transduction pathway to repress hypothalamic gonadotropin-releasing hormone gene expression. The Embo Journal. 15: 538-47. PMID 8599937 DOI: 10.1002/J.1460-2075.1996.Tb00386.X  1
1995 Bergamaschi S, Binetti G, Govoni S, Wetsel WC, Battaini F, Trabucchi M, Bianchetti A, Racchi M. Defective phorbol ester-stimulated secretion of beta-amyloid precursor protein from Alzheimer's disease fibroblasts. Neuroscience Letters. 201: 1-5. PMID 8830300 DOI: 10.1016/0304-3940(95)12168-4  1
1995 Wetsel WC, Liposits Z, Seidah NG, Collins S. Expression of candidate pro-GnRH processing enzymes in rat hypothalamus and an immortalized hypothalamic neuronal cell line. Neuroendocrinology. 62: 166-77. PMID 8584116 DOI: 10.1159/000127001  1
1995 Olson BR, Scott DC, Wetsel WC, Elliot SJ, Tomic M, Stojilkovic S, Nieman LK, Wray S. Effects of insulin-like growth factors I and II and insulin on the immortalized hypothalamic GTI-7 cell line. Neuroendocrinology. 62: 155-65. PMID 8584115 DOI: 10.1159/000127000  1
1995 Battaini F, Elkabes S, Bergamaschi S, Ladisa V, Lucchi L, De Graan PN, Schuurman T, Wetsel WC, Trabucchi M, Govoni S. Protein kinase C activity, translocation, and conventional isoforms in aging rat brain. Neurobiology of Aging. 16: 137-48. PMID 7777132 DOI: 10.1016/0197-4580(94)00154-5  1
1995 Wetsel WC. Immortalized hypothalamic luteinizing hormone-releasing hormone (LHRH) neurons: a new tool for dissecting the molecular and cellular basis of LHRH physiology. Cellular and Molecular Neurobiology. 15: 43-78. PMID 7648609 DOI: 10.1007/Bf02069558  1
1995 Bouché M, Zappelli F, Polimeni M, Adamo S, Wetsel WC, Senni MI, Molinaro M. Rapid activation and down-regulation of protein kinase C alpha in 12-O-Tetradecanoylphorbol-13-acetate-induced differentiation of human rhabdomyosarcoma cells. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 6: 845-52. PMID 7547506  1
1994 Battaini F, Garbillo G, Bergamaschi S, Parenti M, Wetsel WC, Govoni S, Trabucchi M. Regulation of protein kinase C in NG108-15 cell differentiation. Biochemical and Biophysical Research Communications. 201: 135-42. PMID 8198566 DOI: 10.1006/Bbrc.1994.1679  1
1994 Ghalayini AJ, Koutz CA, Wetsel WC, Hannun YA, Anderson RE. Immunolocalization of PKC zeta in rat photoreceptor inner segments. Current Eye Research. 13: 145-50. PMID 8194361 DOI: 10.3109/02713689409042409  1
1994 Battaini F, Pascale A, Lucchi L, Racchi M, Bergamaschi S, Parenti M, Wetsel WC, Govoni S, Trabucchi M. Expression and regulation of calcium-independent protein kinase C in NG 108-15 cell differentiation. Biochemical and Biophysical Research Communications. 203: 1423-31. PMID 7945290 DOI: 10.1006/Bbrc.1994.2344  1
1994 Racchi M, Bergamaschi S, Govoni S, Wetsel WC, Bianchetti A, Binetti G, Battaini F, Trabucchi M. Characterization and distribution of protein kinase C isoforms in human skin fibroblasts. Archives of Biochemistry and Biophysics. 314: 107-11. PMID 7944381 DOI: 10.1006/Abbi.1994.1417  1
1993 Wetsel WC, Eraly SA, Whyte DB, Mellon PL. Regulation of gonadotropin-releasing hormone by protein kinase-A and -C in immortalized hypothalamic neurons. Endocrinology. 132: 2360-70. PMID 8504741 DOI: 10.1210/Endo.132.6.8504741  1
1993 Khan WA, Blobe G, Halpern A, Taylor W, Wetsel WC, Burns D, Loomis C, Hannun YA. Selective regulation of protein kinase C isoenzymes by oleic acid in human platelets. The Journal of Biological Chemistry. 268: 5063-8. PMID 8444883  1
1993 Favit A, Wetsel WC, Negro-Vilar A. Differential expression of gamma-aminobutyric acid receptors in immortalized luteinizing hormone-releasing hormone neurons. Endocrinology. 133: 1983-9. PMID 8404645 DOI: 10.1210/Endo.133.5.8404645  1
1993 Merchenthaler I, Liposits Z, Reid JJ, Wetsel WC. Light and electron microscopic immunocytochemical localization of PKC delta immunoreactivity in the rat central nervous system. The Journal of Comparative Neurology. 336: 378-99. PMID 8263228 DOI: 10.1002/Cne.903360306  1
1993 Migliaccio S, Wetsel WC, Fox WM, Washburn TF, Korach KS. Endogenous protein kinase-C activation in osteoblast-like cells modulates responsiveness to estrogen and estrogen receptor levels. Molecular Endocrinology (Baltimore, Md.). 7: 1133-43. PMID 8247015 DOI: 10.1210/Mend.7.9.8247015  1
1993 Blobe GC, Sachs CW, Khan WA, Fabbro D, Stabel S, Wetsel WC, Obeid LM, Fine RL, Hannun YA. Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKC alpha. The Journal of Biological Chemistry. 268: 658-64. PMID 8093247  1
1992 Wetsel WC, Valença MM, Merchenthaler I, Liposits Z, López FJ, Weiner RI, Mellon PL, Negro-Vilar A. Intrinsic pulsatile secretory activity of immortalized luteinizing hormone-releasing hormone-secreting neurons. Proceedings of the National Academy of Sciences of the United States of America. 89: 4149-53. PMID 1570341 DOI: 10.1073/Pnas.89.9.4149  1
1992 Wetsel WC, Khan WA, Merchenthaler I, Rivera H, Halpern AE, Phung HM, Negro-Vilar A, Hannun YA. Tissue and cellular distribution of the extended family of protein kinase C isoenzymes. The Journal of Cell Biology. 117: 121-33. PMID 1556149 DOI: 10.1083/Jcb.117.1.121  1
1992 Alessenko A, Khan WA, Wetsel WC, Hannun YA. Selective changes in protein kinase C isoenzymes in rat liver nuclei during liver regeneration. Biochemical and Biophysical Research Communications. 182: 1333-9. PMID 1540177 DOI: 10.1016/0006-291X(92)91879-U  1
1992 Mellon PL, Wetsel WC, Windle JJ, Valença MM, Goldsmith PC, Whyte DB, Eraly SA, Negro-Vilar A, Weiner RI. Immortalized hypothalamic gonadotropin-releasing hormone neurons. Ciba Foundation Symposium. 168: 104-17; discussion 1. PMID 1330456  1
1991 Liposits Z, Merchenthaler I, Wetsel WC, Reid JJ, Mellon PL, Weiner RI, Negro-Vilar A. Morphological characterization of immortalized hypothalamic neurons synthesizing luteinizing hormone-releasing hormone. Endocrinology. 129: 1575-83. PMID 1874189 DOI: 10.1210/Endo-129-3-1575  1
1991 Wetsel WC, Mellon PL, Weiner RI, Negro-Vilar A. Metabolism of pro-luteinizing hormone-releasing hormone in immortalized hypothalamic neurons. Endocrinology. 129: 1584-95. PMID 1714837 DOI: 10.1210/Endo-129-3-1584  1
1989 Wetsel WC, Negro-Vilar A. Testosterone selectively influences protein kinase-C-coupled secretion of proluteinizing hormone-releasing hormone-derived peptides. Endocrinology. 125: 538-47. PMID 2661212 DOI: 10.1210/Endo-125-1-538  1
1988 Valenca MM, Wetsel WC, Culler MD, Negro-Vilar A. Differential secretion of proLHRH fragments in response to [K+], prostaglandin E2 and C kinase activation. Molecular and Cellular Endocrinology. 55: 95-100. PMID 3282935 DOI: 10.1016/0303-7207(88)90095-0  1
1988 Wetsel WC, Culler MD, Johnston CA, Negro-Vilar A. Processing of the luteinizing hormone-releasing hormone precursor in the preoptic area and hypothalamus of the rat. Molecular Endocrinology (Baltimore, Md.). 2: 22-31. PMID 3041260 DOI: 10.1210/Mend-2-1-22  1
1987 Culler MC, Wetsel WC, Valenca MM, Johnston CA, Masotto C, Sar M, Negro-Vilar A. Orchidectomy induces temporal and regional changes in the synthesis and processing of the LHRH prohormone in the rat brain. Advances in Experimental Medicine and Biology. 219: 623-8. PMID 3324686 DOI: 10.1007/978-1-4684-5395-9_32  1
1987 Wetsel WC, Fernstrom JD. In vivo biosynthesis of arginine vasopressin and oxytocin in hypothalami from intact and hypophysectomized rats. Endocrinology. 120: 2562-8. PMID 2883002 DOI: 10.1210/Endo-120-6-2562  1
1986 Wetsel WC, Fernstrom JD. Effect of hypophysectomy on somatostatin-14 and somatostatin-28 biosynthesis in the rat hypothalamus. Brain Research. 370: 315-20. PMID 2871892 DOI: 10.1016/0006-8993(86)90486-5  1
1984 Wetsel WC, Rogers AE, Rutledge A, Leavitt WW. Absence of an effect of dietary corn oil content on plasma prolactin, progesterone, and 17 beta-estradiol in female Sprague-Dawley rats. Cancer Research. 44: 1420-5. PMID 6423274  1
1984 Wetsel WC, Rogers AE. Hepatic prolactin binding in female Sprague-Dawley rats fed a diet high in corn oil. Journal of the National Cancer Institute. 73: 531-6. PMID 6087010 DOI: 10.1093/Jnci/73.2.531  1
1984 Wetsel WC, Rogers AE. Hepatic prolactin binding in female rats fed control or high corn oil diets Federation Proceedings. 43: no. 2379.  1
1981 Wetsel WC, Rogers AE, Newberne PM. Dietary fat and DMBA mammary carcinogenesis in rats. Cancer Detection and Prevention. 4: 535-43. PMID 6819892  1
1981 Rogers AE, Wetsel WC. Mammary carcinogenesis in rats fed different amounts and types of fat. Cancer Research. 41: 3735-7. PMID 6790168  1
1980 Wetsel WC, Rogers AE. Effect of dietary fat on mammary carcinogenesis and serum prolactin in rats Federation Proceedings. 39: 3248.  1
1978 Treichler FR, Wetsel WC. Pressure influences on air-licking behavior of rats Physiological Psychology. 6: 399-402. DOI: 10.3758/Bf03326747  1
1977 Treichler FR, Wetsel WC, Lesner SA. Some characteristics of concurrent discrimination and retention by monkeys Learning and Motivation. 8: 213-228. DOI: 10.1016/0023-9690(77)90006-6  1
1976 Wetsel WC, Riccio DC, Hinderliter CF. Effects of artificial rewarming upon hypothermia-induced retrograde amnesia Physiological Psychology. 4: 201-206. DOI: 10.3758/Bf03326580  1
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