Mark W. Hamblin, MD, PhD - Publications

Affiliations: 
Psychiatry University of Washington, Seattle, Seattle, WA 
Area:
serotonin receptors, stress, addiction

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2006 Sjögren B, Hamblin MW, Svenningsson P. Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors. European Journal of Pharmacology. 552: 1-10. PMID 17064686 DOI: 10.1016/j.ejphar.2006.08.069  0.88
2005 Kohen R, Kirov S, Navaja GP, Happe HK, Hamblin MW, Snoddy JR, Neumaier JF, Petty F. Gene expression profiling in the hippocampus of learned helpless and nonhelpless rats. The Pharmacogenomics Journal. 5: 278-91. PMID 16010284 DOI: 10.1038/sj.tpj.6500322  0.88
2005 Guthrie CR, Murray AT, Franklin AA, Hamblin MW. Differential agonist-mediated internalization of the human 5-hydroxytryptamine 7 receptor isoforms. The Journal of Pharmacology and Experimental Therapeutics. 313: 1003-10. PMID 15716386 DOI: 10.1124/jpet.104.081919  0.88
2004 Béïque JC, Campbell B, Perring P, Hamblin MW, Walker P, Mladenovic L, Andrade R. Serotonergic regulation of membrane potential in developing rat prefrontal cortex: coordinated expression of 5-hydroxytryptamine (5-HT)1A, 5-HT2A, and 5-HT7 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4807-17. PMID 15152041 DOI: 10.1523/JNEUROSCI.5113-03.2004  0.88
2003 Kohen R, Neumaier JF, Hamblin MW, Edwards E. Congenitally learned helpless rats show abnormalities in intracellular signaling. Biological Psychiatry. 53: 520-9. PMID 12644357 DOI: 10.1016/S0006-3223(02)01503-2  0.88
2001 Kohen R, Fashingbauer LA, Heidmann DE, Guthrie CR, Hamblin MW. Cloning of the mouse 5-HT6 serotonin receptor and mutagenesis studies of the third cytoplasmic loop. Brain Research. Molecular Brain Research. 90: 110-7. PMID 11406289 DOI: 10.1016/S0169-328X(01)00090-0  0.88
2001 Masellis M, Basile VS, Meltzer HY, Lieberman JA, Sevy S, Goldman DA, Hamblin MW, Macciardi FM, Kennedy JL. Lack of association between the T-->C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia. Schizophrenia Research. 47: 49-58. PMID 11163544 DOI: 10.1016/S0920-9964(00)00016-5  0.88
2000 Neumaier JF, Sexton TJ, Hamblin MW, Beck SG. Corticosteroids regulate 5-HT(1A) but not 5-HT(1B) receptor mRNA in rat hippocampus. Brain Research. Molecular Brain Research. 82: 65-73. PMID 11042358 DOI: 10.1016/S0169-328X(00)00181-9  0.88
2000 Kohen R, Heidmann DE, Anthony J, White SS, Hamblin MW, Szot P. Changes in 5-HT(7) serotonin receptor mRNA expression with aging in rat brain. Brain Research. Molecular Brain Research. 79: 163-8. PMID 10925155 DOI: 10.1016/S0169-328X(00)00103-0  0.88
1998 Hamblin MW, Guthrie CR, Kohen R, Heidmann DE. Gs protein-coupled serotonin receptors: receptor isoforms and functional differences. Annals of the New York Academy of Sciences. 861: 31-7. PMID 9928236 DOI: 10.1111/j.1749-6632.1998.tb10170.x  0.88
1998 Heidmann DE, Szot P, Kohen R, Hamblin MW. Function and distribution of three rat 5-hydroxytryptamine7 (5-HT7) receptor isoforms produced by alternative splicing. Neuropharmacology. 37: 1621-32. PMID 9886685  0.88
1998 Baker LP, Nielsen MD, Impey S, Metcalf MA, Poser SW, Chan G, Obrietan K, Hamblin MW, Storm DR. Stimulation of type 1 and type 8 Ca2+/calmodulin-sensitive adenylyl cyclases by the Gs-coupled 5-hydroxytryptamine subtype 5-HT7A receptor. The Journal of Biological Chemistry. 273: 17469-76. PMID 9651336 DOI: 10.1074/jbc.273.28.17469  0.88
1998 Martin GR, Eglen RM, Hamblin MW, Hoyer D, Yocca F. The structure and signalling properties of 5-HT receptors: an endless diversity? Trends in Pharmacological Sciences. 19: 2-4. PMID 9509891 DOI: 10.1016/S0165-6147(97)01143-7  0.88
1998 Martin GR, Eglen RM, Hoyer D, Hamblin MW, Yocca F. Conference on Advances in Serotonin Receptor Research: Molecular Biology, Signal Transduction, and Therapeutics, San Francisco, California, October 8-10, 1997: Preface Annals of the New York Academy of Sciences. 861: XIII-XIV. DOI: 10.1111/j.1749-6632.1998.tb10166.x  0.88
1997 Heidmann DE, Metcalf MA, Kohen R, Hamblin MW. Four 5-hydroxytryptamine7 (5-HT7) receptor isoforms in human and rat produced by alternative splicing: species differences due to altered intron-exon organization. Journal of Neurochemistry. 68: 1372-81. PMID 9084407  0.88
1997 Neumaier JF, Petty F, Kramer GL, Szot P, Hamblin MW. Learned helplessness increases 5-hydroxytryptamine1B receptor mRNA levels in the rat dorsal raphe nucleus. Biological Psychiatry. 41: 668-74. PMID 9066990 DOI: 10.1016/S0006-3223(96)00114-X  0.88
1996 Neumaier JF, Root DC, Hamblin MW. Chronic fluoxetine reduces serotonin transporter mRNA and 5-HT1B mRNA in a sequential manner in the rat dorsal raphe nucleus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 515-22. PMID 8914125 DOI: 10.1016/S0893-133X(96)00095-4  0.88
1996 Neumaier JF, Szot P, Peskind ER, Dorsa DM, Hamblin MW. Serotonergic lesioning differentially affects presynaptic and postsynaptic 5-HT1B receptor mRNA levels in rat brain. Brain Research. 722: 50-8. PMID 8813349  0.88
1996 Kohen R, Metcalf MA, Khan N, Druck T, Huebner K, Lachowicz JE, Meltzer HY, Sibley DR, Roth BL, Hamblin MW. Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. Journal of Neurochemistry. 66: 47-56. PMID 8522988  0.88
1995 Ward RP, Hamblin MW, Lachowicz JE, Hoffman BJ, Sibley DR, Dorsa DM. Localization of serotonin subtype 6 receptor messenger RNA in the rat brain by in situ hybridization histochemistry. Neuroscience. 64: 1105-11. PMID 7753378 DOI: 10.1016/0306-4522(94)00439-C  0.88
1995 Gelernter J, Rao PA, Pauls DL, Hamblin MW, Sibley DR, Kidd KK. Assignment of the 5HT7 receptor gene (HTR7) to chromosome 10q and exclusion of genetic linkage with Tourette syndrome. Genomics. 26: 207-9. PMID 7601444 DOI: 10.1016/0888-7543(95)80202-W  0.88
1993 Shen Y, Monsma FJ, Metcalf MA, Jose PA, Hamblin MW, Sibley DR. Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. The Journal of Biological Chemistry. 268: 18200-4. PMID 8394362  0.88
1993 Dobie DJ, Merchant KM, Hamblin MW, Vatassery GT, Dysken MW, Dorsa DM. Blunting of the neurotensin mRNA response to haloperidol in the striatum of aging rats: possible relationship to decline in dopamine D2 receptor expression. Brain Research. 616: 105-13. PMID 8358601 DOI: 10.1016/0006-8993(93)90198-V  0.88
1993 Monsma FJ, Shen Y, Ward RP, Hamblin MW, Sibley DR. Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Molecular Pharmacology. 43: 320-7. PMID 7680751  0.88
1992 Metcalf MA, McGuffin RW, Hamblin MW. Conversion of the human 5-HT1D beta serotonin receptor to the rat 5-HT1B ligand-binding phenotype by Thr355Asn site directed mutagenesis. Biochemical Pharmacology. 44: 1917-20. PMID 1449511 DOI: 10.1016/0006-2952(92)90092-W  0.88
1992 Hamblin MW, Metcalf MA, McGuffin RW, Karpells S. Molecular cloning and functional characterization of a human 5-HT1B serotonin receptor: a homologue of the rat 5-HT1B receptor with 5-HT1D-like pharmacological specificity. Biochemical and Biophysical Research Communications. 184: 752-9. PMID 1315531 DOI: 10.1016/0006-291X(92)90654-4  0.88
1992 Hamblin MW, McGuffin RW, Metcalf MA, Dorsa DM, Merchant KM. Distinct 5-HT1B and 5-HT1D serotonin receptors in rat: Structural and pharmacological comparison of the two cloned receptors Molecular and Cellular Neuroscience. 3: 578-587. DOI: 10.1016/1044-7431(92)90070-I  0.88
1991 Roth BL, Hamblin MW, Ciaranello RD. Developmental regulation of 5-HT2 and 5-HT1c mRNA and receptor levels. Brain Research. Developmental Brain Research. 58: 51-8. PMID 2015654 DOI: 10.1016/0165-3806(91)90236-C  0.88
1991 Hamblin MW, Metcalf MA. Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor. Molecular Pharmacology. 40: 143-8. PMID 1652050  0.88
1989 Ariani K, Hamblin MW, Tan GL, Stratford CA, Ciaranello RD. G protein dependent alterations in [125I]iodocyanopindolol and +/- cyanopindolol binding at 5-HT1B binding sites in rat brain membranes. Neurochemical Research. 14: 835-43. PMID 2512511 DOI: 10.1007/BF00964812  0.88
1988 Stratford CA, Tan GL, Hamblin MW, Ciaranello RD. Differential inactivation and G protein reconstitution of subtypes of [3H]5-hydroxytryptamine binding sites in brain. Molecular Pharmacology. 34: 527-36. PMID 3139989  0.88
1987 Hamblin MW, Adriaenssens PI, Ariani K, Cawthon RM, Stratford CA, Tan GL, Ciaranello RD. Ascorbic acid prevents nonreceptor "specific" binding of [3H]-5-hydroxytryptamine to bovine cerebral cortex membranes. The Journal of Pharmacology and Experimental Therapeutics. 240: 701-11. PMID 3559968  0.88
1987 Hamblin MW, Ariani K, Adriaenssens PI, Ciaranello RD. [3H]dihydroergotamine as a high-affinity, slowly dissociating radioligand for 5-HT1B binding sites in rat brain membranes: evidence for guanine nucleotide regulation of agonist affinity states. The Journal of Pharmacology and Experimental Therapeutics. 243: 989-1001. PMID 2826763  0.88
1985 Leff SE, Hamblin MW, Creese I. Interactions of dopamine agonists with brain D1 receptors labeled by 3H-antagonists. Evidence for the presence of high and low affinity agonist-binding states. Molecular Pharmacology. 27: 171-83. PMID 3969066  0.88
1984 Hamblin MW, Leff SE, Creese I. Interactions of agonists with D-2 dopamine receptors: evidence for a single receptor population existing in multiple agonist affinity-states in rat striatal membranes. Biochemical Pharmacology. 33: 877-87. PMID 6712712 DOI: 10.1016/0006-2952(84)90441-6  0.88
1983 Creese I, Sibley DR, Hamblin MW, Leff SE. The classification of dopamine receptors: relationship to radioligand binding. Annual Review of Neuroscience. 6: 43-71. PMID 6220666 DOI: 10.1146/annurev.ne.06.030183.000355  0.88
1983 Hamblin MW, Creese I. Behavioral and radioligand binding evidence for irreversible dopamine receptor blockade by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline. Life Sciences. 32: 2247-55. PMID 6133202 DOI: 10.1016/0024-3205(83)90423-X  0.88
1983 Creese I, Morrow AL, Hamblin MW, Leff SE, Sibley DR. Radioligand binding studies of dopamine receptors in the central nervous system Advances in the Biosciences. 44: 1-50.  0.88
1982 Hamblin MW, Creese I. Heat treatment mimics guanosine-5'-triphosphate effects on dopaminergic 3H-ligand binding to bovine caudate membranes. Molecular Pharmacology. 21: 52-6. PMID 7132962  0.88
1982 Hamblin MW, Creese I. 3H-dopamine binding to rat striatal D-2 and D-3 sites: enhancement by magnesium and inhibition by guanine nucleotides and sodium. Life Sciences. 30: 1587-95. PMID 7078356 DOI: 10.1016/0024-3205(82)90248-X  0.88
1982 Creese I, Morrow AL, Leff SE, Sibley DR, Hamblin MW. Dopamine receptors in the central nervous system. International Review of Neurobiology. 23: 255-301. PMID 6749737  0.88
1982 Hamblin MW, Creese I. Phenoxybenzamine treatment differentiates dopaminergic 3H-ligand binding sites in bovine caudate membranes. Molecular Pharmacology. 21: 44-51. PMID 6127621  0.88
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