Mark W. Hamblin, MD, PhD - Publications

Affiliations: 
Psychiatry University of Washington, Seattle, Seattle, WA 
Area:
serotonin receptors, stress, addiction

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Andrade R, Barnes NM, Baxter G, Bockaert J, Branchek T, Butler A, Cohen ML, Dumuis A, Eglen RM, Göthert M, Hamblin M, Hamon M, Hartig PR, Hen R, Hensler J, et al. 5-Hydroxytryptamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f1/2019.4  0.642
2006 Sjögren B, Hamblin MW, Svenningsson P. Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors. European Journal of Pharmacology. 552: 1-10. PMID 17064686 DOI: 10.1016/J.Ejphar.2006.08.069  0.524
2005 Kohen R, Kirov S, Navaja GP, Happe HK, Hamblin MW, Snoddy JR, Neumaier JF, Petty F. Gene expression profiling in the hippocampus of learned helpless and nonhelpless rats. The Pharmacogenomics Journal. 5: 278-91. PMID 16010284 DOI: 10.1038/Sj.Tpj.6500322  0.565
2005 Guthrie CR, Murray AT, Franklin AA, Hamblin MW. Differential agonist-mediated internalization of the human 5-hydroxytryptamine 7 receptor isoforms. The Journal of Pharmacology and Experimental Therapeutics. 313: 1003-10. PMID 15716386 DOI: 10.1124/Jpet.104.081919  0.519
2004 Béïque JC, Campbell B, Perring P, Hamblin MW, Walker P, Mladenovic L, Andrade R. Serotonergic regulation of membrane potential in developing rat prefrontal cortex: coordinated expression of 5-hydroxytryptamine (5-HT)1A, 5-HT2A, and 5-HT7 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4807-17. PMID 15152041 DOI: 10.1523/Jneurosci.5113-03.2004  0.463
2003 Kohen R, Neumaier JF, Hamblin MW, Edwards E. Congenitally learned helpless rats show abnormalities in intracellular signaling. Biological Psychiatry. 53: 520-9. PMID 12644357 DOI: 10.1016/S0006-3223(02)01503-2  0.592
2001 Kohen R, Fashingbauer LA, Heidmann DE, Guthrie CR, Hamblin MW. Cloning of the mouse 5-HT6 serotonin receptor and mutagenesis studies of the third cytoplasmic loop. Brain Research. Molecular Brain Research. 90: 110-7. PMID 11406289 DOI: 10.1016/S0169-328X(01)00090-0  0.524
2001 Masellis M, Basile VS, Meltzer HY, Lieberman JA, Sevy S, Goldman DA, Hamblin MW, Macciardi FM, Kennedy JL. Lack of association between the T-->C 267 serotonin 5-HT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia. Schizophrenia Research. 47: 49-58. PMID 11163544 DOI: 10.1016/S0920-9964(00)00016-5  0.458
2000 Neumaier JF, Sexton TJ, Hamblin MW, Beck SG. Corticosteroids regulate 5-HT(1A) but not 5-HT(1B) receptor mRNA in rat hippocampus. Brain Research. Molecular Brain Research. 82: 65-73. PMID 11042358 DOI: 10.1016/S0169-328X(00)00181-9  0.668
2000 Kohen R, Heidmann DE, Anthony J, White SS, Hamblin MW, Szot P. Changes in 5-HT(7) serotonin receptor mRNA expression with aging in rat brain. Brain Research. Molecular Brain Research. 79: 163-8. PMID 10925155 DOI: 10.1016/S0169-328X(00)00103-0  0.531
1998 Hamblin MW, Guthrie CR, Kohen R, Heidmann DE. Gs protein-coupled serotonin receptors: receptor isoforms and functional differences. Annals of the New York Academy of Sciences. 861: 31-7. PMID 9928236 DOI: 10.1111/J.1749-6632.1998.Tb10170.X  0.527
1998 Heidmann DE, Szot P, Kohen R, Hamblin MW. Function and distribution of three rat 5-hydroxytryptamine7 (5-HT7) receptor isoforms produced by alternative splicing. Neuropharmacology. 37: 1621-32. PMID 9886685 DOI: 10.1016/S0028-3908(98)00070-7  0.575
1998 Baker LP, Nielsen MD, Impey S, Metcalf MA, Poser SW, Chan G, Obrietan K, Hamblin MW, Storm DR. Stimulation of type 1 and type 8 Ca2+/calmodulin-sensitive adenylyl cyclases by the Gs-coupled 5-hydroxytryptamine subtype 5-HT7A receptor. The Journal of Biological Chemistry. 273: 17469-76. PMID 9651336 DOI: 10.1074/Jbc.273.28.17469  0.544
1998 Martin GR, Eglen RM, Hamblin MW, Hoyer D, Yocca F. The structure and signalling properties of 5-HT receptors: an endless diversity? Trends in Pharmacological Sciences. 19: 2-4. PMID 9509891 DOI: 10.1016/S0165-6147(97)01143-7  0.461
1998 Martin GR, Eglen RM, Hoyer D, Hamblin MW, Yocca F. Conference on Advances in Serotonin Receptor Research: Molecular Biology, Signal Transduction, and Therapeutics, San Francisco, California, October 8-10, 1997: Preface Annals of the New York Academy of Sciences. 861: XIII-XIV. DOI: 10.1111/J.1749-6632.1998.Tb10166.X  0.368
1997 Heidmann DE, Metcalf MA, Kohen R, Hamblin MW. Four 5-hydroxytryptamine7 (5-HT7) receptor isoforms in human and rat produced by alternative splicing: species differences due to altered intron-exon organization. Journal of Neurochemistry. 68: 1372-81. PMID 9084407 DOI: 10.1046/J.1471-4159.1997.68041372.X  0.526
1997 Neumaier JF, Petty F, Kramer GL, Szot P, Hamblin MW. Learned helplessness increases 5-hydroxytryptamine1B receptor mRNA levels in the rat dorsal raphe nucleus. Biological Psychiatry. 41: 668-74. PMID 9066990 DOI: 10.1016/S0006-3223(96)00114-X  0.666
1996 Neumaier JF, Root DC, Hamblin MW. Chronic fluoxetine reduces serotonin transporter mRNA and 5-HT1B mRNA in a sequential manner in the rat dorsal raphe nucleus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 515-22. PMID 8914125 DOI: 10.1016/S0893-133X(96)00095-4  0.66
1996 Neumaier JF, Szot P, Peskind ER, Dorsa DM, Hamblin MW. Serotonergic lesioning differentially affects presynaptic and postsynaptic 5-HT1B receptor mRNA levels in rat brain. Brain Research. 722: 50-8. PMID 8813349 DOI: 10.1016/0006-8993(96)00178-3  0.669
1996 Kohen R, Metcalf MA, Khan N, Druck T, Huebner K, Lachowicz JE, Meltzer HY, Sibley DR, Roth BL, Hamblin MW. Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. Journal of Neurochemistry. 66: 47-56. PMID 8522988 DOI: 10.1046/J.1471-4159.1996.66010047.X  0.532
1996 Roth B, Hamblin M, Sibley D, Meltzer H. Binding of atypical antipsychotic drugs to novel neurotransmitter receptors Schizophrenia Research. 18: 142. DOI: 10.1016/0920-9964(96)85467-3  0.346
1996 Neumaier J, Petty F, Szot P, Kramer J, Hamblin M. Rat dorsal raphe 5-HT1B receptor MRNA is differentially regulated by fluoxetine and learned helplessness Biological Psychiatry. 39: 533. DOI: 10.1016/0006-3223(96)84063-7  0.655
1995 Ward RP, Hamblin MW, Lachowicz JE, Hoffman BJ, Sibley DR, Dorsa DM. Localization of serotonin subtype 6 receptor messenger RNA in the rat brain by in situ hybridization histochemistry. Neuroscience. 64: 1105-11. PMID 7753378 DOI: 10.1016/0306-4522(94)00439-C  0.414
1995 Gelernter J, Rao PA, Pauls DL, Hamblin MW, Sibley DR, Kidd KK. Assignment of the 5HT7 receptor gene (HTR7) to chromosome 10q and exclusion of genetic linkage with Tourette syndrome. Genomics. 26: 207-9. PMID 7601444 DOI: 10.1016/0888-7543(95)80202-W  0.353
1993 Shen Y, Monsma FJ, Metcalf MA, Jose PA, Hamblin MW, Sibley DR. Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. The Journal of Biological Chemistry. 268: 18200-4. PMID 8394362  0.501
1993 Dobie DJ, Merchant KM, Hamblin MW, Vatassery GT, Dysken MW, Dorsa DM. Blunting of the neurotensin mRNA response to haloperidol in the striatum of aging rats: possible relationship to decline in dopamine D2 receptor expression. Brain Research. 616: 105-13. PMID 8358601 DOI: 10.1016/0006-8993(93)90198-V  0.433
1993 Monsma FJ, Shen Y, Ward RP, Hamblin MW, Sibley DR. Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Molecular Pharmacology. 43: 320-7. PMID 7680751  0.47
1992 Hamblin MW, McGuffin RW, Metcalf MA, Dorsa DM, Merchant KM. Distinct 5-HT(1B) and 5-HT(1D) serotonin receptors in rat: Structural and pharmacological comparison of the two cloned receptors. Molecular and Cellular Neurosciences. 3: 578-87. PMID 19912901 DOI: 10.1016/1044-7431(92)90070-I  0.547
1992 Metcalf MA, McGuffin RW, Hamblin MW. Conversion of the human 5-HT1D beta serotonin receptor to the rat 5-HT1B ligand-binding phenotype by Thr355Asn site directed mutagenesis. Biochemical Pharmacology. 44: 1917-20. PMID 1449511 DOI: 10.1016/0006-2952(92)90092-W  0.444
1992 Hamblin MW, Metcalf MA, McGuffin RW, Karpells S. Molecular cloning and functional characterization of a human 5-HT1B serotonin receptor: a homologue of the rat 5-HT1B receptor with 5-HT1D-like pharmacological specificity. Biochemical and Biophysical Research Communications. 184: 752-9. PMID 1315531 DOI: 10.1016/0006-291X(92)90654-4  0.443
1992 Hamblin MW, McGuffin RW, Metcalf MA, Dorsa DM, Merchant KM. Distinct 5-HT1B and 5-HT1D serotonin receptors in rat: Structural and pharmacological comparison of the two cloned receptors Molecular and Cellular Neuroscience. 3: 578-587. DOI: 10.1016/1044-7431(92)90070-I  0.389
1991 Roth BL, Hamblin MW, Ciaranello RD. Developmental regulation of 5-HT2 and 5-HT1c mRNA and receptor levels. Brain Research. Developmental Brain Research. 58: 51-8. PMID 2015654 DOI: 10.1016/0165-3806(91)90236-C  0.505
1991 Hamblin MW, Metcalf MA. Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor. Molecular Pharmacology. 40: 143-8. PMID 1652050  0.355
1990 Roth BL, Hamblin M, Ciaranello RD. Regulation of 5-HT2 and 5-HT1C serotonin receptor levels. Methodology and mechanisms. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 3: 427-33. PMID 2078277  0.475
1987 Hamblin MW, Adriaenssens PI, Ariani K, Cawthon RM, Stratford CA, Tan GL, Ciaranello RD. Ascorbic acid prevents nonreceptor "specific" binding of [3H]-5-hydroxytryptamine to bovine cerebral cortex membranes. The Journal of Pharmacology and Experimental Therapeutics. 240: 701-11. PMID 3559968  0.348
1983 Creese I, Sibley DR, Hamblin MW, Leff SE. The classification of dopamine receptors: relationship to radioligand binding. Annual Review of Neuroscience. 6: 43-71. PMID 6220666 DOI: 10.1146/Annurev.Ne.06.030183.000355  0.352
1981 Creese I, Sibley DR, Leff S, Hamblin M. Dopamine receptors: subtypes, localization and regulation. Federation Proceedings. 40: 147-52. PMID 7007083  0.31
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