| Year |
Citation |
Score |
| 2023 |
Hu L, Liu M, Tang B, Li Q, Pan BS, Xu C, Lin HK. Posttranslational regulation of liver kinase B1 (LKB1) in human cancer. The Journal of Biological Chemistry. 104570. PMID 36870679 DOI: 10.1016/j.jbc.2023.104570 |
0.301 |
|
| 2023 |
Tsai PJ, Lai YH, Manne RK, Tsai YS, Sarbassov D, Lin HK. Correction: Akt: a key transducer in cancer. Journal of Biomedical Science. 30: 7. PMID 36698128 DOI: 10.1186/s12929-023-00900-y |
0.318 |
|
| 2022 |
Tsai PJ, Lai YH, Manne RK, Tsai YS, Sarbassov D, Lin HK. Akt: a key transducer in cancer. Journal of Biomedical Science. 29: 76. PMID 36180910 DOI: 10.1186/s12929-022-00860-9 |
0.325 |
|
| 2020 |
Hu YC, Yeh S, Yeh SD, Sampson ER, Huang J, Li P, Hsu CL, Ting HJ, Lin HK, Wang L, Kim E, Ni J, Chang C. Correction: Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer. The Journal of Biological Chemistry. 295: 17382. PMID 33453984 DOI: 10.1074/jbc.AAC120.016763 |
0.827 |
|
| 2020 |
Cai Z, Peng D, Lin HK. AMPK maintains TCA cycle through sequential phosphorylation of PDHA to promote tumor metastasis. Cell Stress. 4: 273-277. PMID 33336150 DOI: 10.15698/cst2020.12.238 |
0.308 |
|
| 2020 |
Hu YC, Yeh S, Yeh SD, Sampson ER, Huang J, Li P, Hsu CL, Ting HJ, Lin HK, Wang L, Kim E, Ni J, Chang C. Correction: Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer. The Journal of Biological Chemistry. 295: 17382. PMID 33310747 DOI: 10.1074/jbc.AAC120.016763 |
0.827 |
|
| 2020 |
Cai Z, Li CF, Han F, Liu C, Zhang A, Hsu CC, Peng D, Zhang X, Jin G, Rezaeian AH, Wang G, Zhang W, Pan BS, Wang CY, Wang YH, ... ... Lin HK, et al. Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis. Molecular Cell. PMID 33022274 DOI: 10.1016/j.molcel.2020.09.018 |
0.323 |
|
| 2020 |
Snider AJ, Seeds MC, Johnstone L, Snider JM, Hallmark B, Dutta R, Moraga Franco C, Parks JS, Bensen JT, Broeckling CD, Mohler JL, Smith GJ, Fontham ETH, Lin HK, Bresette W, et al. Identification of Plasma Glycosphingolipids as Potential Biomarkers for Prostate Cancer (PCa) Status. Biomolecules. 10. PMID 33007922 DOI: 10.3390/biom10101393 |
0.464 |
|
| 2020 |
Cai Z, Moten A, Peng D, Hsu CC, Pan BS, Kumar Manne R, Li HY, Lin HK. The Skp2 Pathway: A Critical Target for Cancer Therapy. Seminars in Cancer Biology. PMID 32014608 DOI: 10.1016/J.Semcancer.2020.01.013 |
0.409 |
|
| 2019 |
Ji Z, Zhao W, Lin HK, Zhou X. Systematically understanding the immunity leading to CRPC progression. Plos Computational Biology. 15: e1007344. PMID 31504033 DOI: 10.1371/Journal.Pcbi.1007344 |
0.448 |
|
| 2019 |
Wu X, Park M, Sarbassova DA, Ying H, Lee MG, Bhattacharya R, Ellis L, Peterson CB, Hung MC, Lin HK, Bersimbaev RI, Song MS, Sarbassov DD. A Chirality-Dependent Action of Vitamin C in Suppressing KRAS Mutant Tumor Growth by the Oxidative Combination: Rationale for Cancer Therapeutics. International Journal of Cancer. PMID 31472018 DOI: 10.1002/Ijc.32658 |
0.318 |
|
| 2019 |
Li Y, Huang JH, Wang JL, Song GT, Tang D, Yao F, Lin HK, Yan W, Li HY, Xu ZG, Chen ZZ. Diversity-Oriented Synthesis of Imidazo-Dipyridines with Anticancer Activity via Groebke-Blackburn-Bienaymé and TBAB-Mediated Cascade Reaction in One Pot. The Journal of Organic Chemistry. PMID 31357859 DOI: 10.1021/acs.joc.9b01385 |
0.321 |
|
| 2018 |
Han F, Li CF, Cai Z, Zhang X, Jin G, Zhang WN, Xu C, Wang CY, Morrow J, Zhang S, Xu D, Wang G, Lin HK. The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance. Nature Communications. 9: 4728. PMID 30413706 DOI: 10.1038/s41467-018-07188-9 |
0.301 |
|
| 2018 |
Liu C, Cai Z, Jin G, Peng D, Pan BS, Zhang X, Han F, Xu X, Lin HK. Abnormal gametogenesis induced by p53 deficiency promotes tumor progression and drug resistance. Cell Discovery. 4: 54. PMID 30302273 DOI: 10.1038/S41421-018-0054-X |
0.307 |
|
| 2018 |
Lee SW, Lin HK. A new mechanism for LKB1 activation. Molecular & Cellular Oncology. 5: e1035691. PMID 30250874 DOI: 10.1080/23723556.2015.1035691 |
0.366 |
|
| 2017 |
Ruan D, He J, Li CF, Lee HJ, Liu J, Lin HK, Chan CH. Skp2 deficiency restricts the progression and stem cell features of castration-resistant prostate cancer by destabilizing Twist. Oncogene. PMID 28346424 DOI: 10.1038/onc.2017.64 |
0.49 |
|
| 2016 |
Zhang X, Lin HK. NBR2-GLUT1 axis regulates cancer cell sensitivity to biguanides. Cell Cycle (Georgetown, Tex.). 0. PMID 27929708 DOI: 10.1080/15384101.2016.1263498 |
0.44 |
|
| 2016 |
Rezaeian AH, Li CF, Wu CY, Zhang X, Delacerda J, You MJ, Han F, Cai Z, Jeong YS, Jin G, Phan L, Chou PC, Lee MH, Hung MC, Sarbassov D, ... Lin HK, et al. A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis. Nature Cell Biology. PMID 27918549 DOI: 10.1038/ncb3445 |
0.336 |
|
| 2016 |
Bawa-Khalfe T, Yang FM, Ritho J, Lin HK, Cheng J, Yeh ET. SENP1 regulates PTEN stability to dictate prostate cancer development. Oncotarget. PMID 27852060 DOI: 10.18632/Oncotarget.13283 |
0.63 |
|
| 2016 |
Sharma S, Xing F, Liu Y, Wu K, Said N, Pochampally R, Shiozawa Y, Lin HK, Balaji KC, Watabe K. Secreted Protein Acidic and Rich in Cysteine (SPARC) Mediates Metastatic Dormancy of Prostate Cancer in the Bone. The Journal of Biological Chemistry. PMID 27422817 DOI: 10.1074/Jbc.M116.737379 |
0.517 |
|
| 2016 |
Li N, Dhar SS, Chen TY, Kan PY, Wei Y, Kim JH, Chan CH, Lin HK, Hung MC, Lee MG. JARID1D is a suppressor and prognostic marker of prostate cancer invasion and metastasis. Cancer Research. PMID 26747897 DOI: 10.1158/0008-5472.CAN-15-0906 |
0.51 |
|
| 2016 |
Chen YA, Lee K, Lin Y, Li C, Yen C, Lin H, Chen Y. Abstract 4418: Identification and characterization of patient-derived PREX2 mutation in HCC Cancer Research. 76: 4418-4418. DOI: 10.1158/1538-7445.Am2016-4418 |
0.326 |
|
| 2015 |
Tsai YT, Chuang MJ, Tang SH, Wu ST, Chen YC, Sun GH, Hsiao PW, Huang SM, Lee HJ, Yu CP, Ho JY, Lin HK, Chen MR, Lin CC, Chang SY, et al. Novel Cancer Therapeutics with Allosteric Modulation of The Mitochondrial C-Raf/DAPK Complex by Raf Inhibitor Combination Therapy. Cancer Research. PMID 26100670 DOI: 10.1158/0008-5472.Can-14-3264 |
0.353 |
|
| 2014 |
Chan CH, Jo U, Kohrman A, Rezaeian AH, Chou PC, Logothetis C, Lin HK. Posttranslational regulation of Akt in human cancer. Cell & Bioscience. 4: 59. PMID 25309720 DOI: 10.1186/2045-3701-4-59 |
0.452 |
|
| 2014 |
Wagner KW, Alam H, Dhar SS, Giri U, Li N, Wei Y, Cascone T, Giri D, Kim J, Ye Y, Multani A, Chan C, Erez B, Saigal B, Lin H, et al. Abstract 5146: The histone demethylase KDM2A is a new promoter of tumorigenesis, drug target and negative prognostic biomarker for non-small cell lung cancer Cancer Research. 74: 5146-5146. DOI: 10.1158/1538-7445.Am2014-5146 |
0.38 |
|
| 2013 |
Chan CH, Morrow JK, Li CF, Gao Y, Jin G, Moten A, Stagg LJ, Ladbury JE, Cai Z, Xu D, Logothetis CJ, Hung MC, Zhang S, Lin HK. Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression. Cell. 154: 556-68. PMID 23911321 DOI: 10.1016/j.cell.2013.06.048 |
0.361 |
|
| 2013 |
Yang WL, Jin G, Li CF, Jeong YS, Moten A, Xu D, Feng Z, Chen W, Cai Z, Darnay B, Gu W, Lin HK. Cycles of ubiquitination and deubiquitination critically regulate growth factor-mediated activation of Akt signaling. Science Signaling. 6: ra3. PMID 23300340 DOI: 10.1126/scisignal.2003197 |
0.32 |
|
| 2013 |
Wu J, Lee SW, Zhang X, Han F, Kwan SY, Yuan X, Yang WL, Jeong YS, Rezaeian AH, Gao Y, Zeng YX, Lin HK. Foxo3a transcription factor is a negative regulator of Skp2 and Skp2 SCF complex. Oncogene. 32: 78-85. PMID 22310285 DOI: 10.1038/Onc.2012.26 |
0.34 |
|
| 2012 |
Wei W, Lin HK. The key role of ubiquitination and sumoylation in signaling and cancer: a research topic. Frontiers in Oncology. 2: 187. PMID 23227454 DOI: 10.3389/Fonc.2012.00187 |
0.405 |
|
| 2012 |
Wang G, Gao Y, Li L, Jin G, Cai Z, Chao JI, Lin HK. K63-linked ubiquitination in kinase activation and cancer. Frontiers in Oncology. 2: 5. PMID 22649774 DOI: 10.3389/Fonc.2012.00005 |
0.344 |
|
| 2012 |
Chan CH, Li CF, Yang WL, Gao Y, Lee SW, Feng Z, Huang HY, Tsai KK, Flores LG, Shao Y, Hazle JD, Yu D, Wei W, Sarbassov D, Hung MC, ... ... Lin HK, et al. The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis. Cell. 149: 1098-111. PMID 22632973 DOI: 10.1016/J.Cell.2012.02.065 |
0.302 |
|
| 2012 |
Wang G, Chan CH, Gao Y, Lin HK. Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis. Chinese Journal of Cancer. 31: 169-77. PMID 22200179 DOI: 10.5732/Cjc.011.10319 |
0.315 |
|
| 2011 |
Samaniego F, Berkova Z, Wise JF, Kerros C, Hawke DH, Karp JE, Lin H, Molldrem JJ, Tao R. PML and PMLRARα Interact with Fas to Regulate Fas-Mediated Apoptosis In Vivo Blood. 118: 2451-2451. DOI: 10.1182/Blood.V118.21.2451.2451 |
0.395 |
|
| 2010 |
Yang W, Zhang X, Lin H. Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development. Oncogene. 29: 4493-4503. PMID 20531303 DOI: 10.1038/Onc.2010.190 |
0.426 |
|
| 2010 |
Chan CH, Lee SW, Wang J, Lin HK. Regulation of Skp2 expression and activity and its role in cancer progression. Thescientificworldjournal. 10: 1001-15. PMID 20526532 DOI: 10.1100/tsw.2010.89 |
0.364 |
|
| 2010 |
Yang WL, Wu CY, Wu J, Lin HK. Regulation of Akt signaling activation by ubiquitination. Cell Cycle (Georgetown, Tex.). 9: 487-97. PMID 20081374 |
0.327 |
|
| 2009 |
Chen Z, Carracedo A, Lin HK, Koutcher JA, Behrendt N, Egia A, Alimonti A, Carver BS, Gerald W, Teruya-Feldstein J, Loda M, Pandolfi PP. Differential p53-independent outcomes of p19(Arf) loss in oncogenesis. Science Signaling. 2: ra44. PMID 19690330 DOI: 10.1126/Scisignal.2000053 |
0.407 |
|
| 2008 |
Chang CC, Yeh MS, Lin HK, Cheng W. The effect of Vibrio alginolyticus infection on caspase-3 expression and activity in white shrimp Litopenaeus vannamei. Fish & Shellfish Immunology. 25: 672-8. PMID 18840531 DOI: 10.1016/j.fsi.2008.09.004 |
0.378 |
|
| 2007 |
Carver BS, Lin H, Chen Z, Trotman L, Scardino PT, Pandolfi PP. 663: XPD (ERCC-2) and Prostate Cancer: Susceptibility Depends on the Degree of DNA Damage and Transcriptional Interference Journal of Urology. 177: 222-223. DOI: 10.1016/S0022-5347(18)30903-0 |
0.543 |
|
| 2005 |
Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, Koutcher JA, Scher HI, Ludwig T, Gerald W, Cordon-Cardo C, Pandolfi PP. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature. 436: 725-30. PMID 16079851 DOI: 10.1038/Nature03918 |
0.535 |
|
| 2004 |
Lin HK, Hu YC, Lee DK, Chang C. Regulation of androgen receptor signaling by PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor through distinct mechanisms in prostate cancer cells. Molecular Endocrinology (Baltimore, Md.). 18: 2409-23. PMID 15205473 DOI: 10.1210/Me.2004-0117 |
0.834 |
|
| 2004 |
Wang L, Lin HK, Hu YC, Xie S, Yang L, Chang C. Suppression of androgen receptor-mediated transactivation and cell growth by the glycogen synthase kinase 3 beta in prostate cells. The Journal of Biological Chemistry. 279: 32444-52. PMID 15178691 DOI: 10.1074/Jbc.M313963200 |
0.82 |
|
| 2004 |
Kang HY, Cho CL, Huang KL, Wang JC, Hu YC, Lin HK, Chang C, Huang KE. Nongenomic androgen activation of phosphatidylinositol 3-kinase/Akt signaling pathway in MC3T3-E1 osteoblasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 19: 1181-90. PMID 15177002 DOI: 10.1359/Jbmr.040306 |
0.759 |
|
| 2004 |
Hu YC, Yeh S, Yeh SD, Sampson ER, Huang J, Li P, Hsu CL, Ting HJ, Lin HK, Wang L, Kim E, Ni J, Chang C. Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer. The Journal of Biological Chemistry. 279: 33438-46. PMID 15166229 DOI: 10.1074/Jbc.M401781200 |
0.842 |
|
| 2004 |
Xie S, Lin HK, Ni J, Yang L, Wang L, di Sant'Agnese PA, Chang C. Regulation of interleukin-6-mediated PI3K activation and neuroendocrine differentiation by androgen signaling in prostate cancer LNCaP cells. The Prostate. 60: 61-7. PMID 15129430 DOI: 10.1002/Pros.20048 |
0.826 |
|
| 2004 |
Lin H, Bergmann S, Pandolfi PP. Cytoplasmic PML Function in TGF-β Signaling. Blood. 104: 481-481. DOI: 10.1182/Blood.V104.11.481.481 |
0.308 |
|
| 2003 |
Altuwaijri S, Lin HK, Chuang KH, Lin WJ, Yeh S, Hanchett LA, Rahman MM, Kang HY, Tsai MY, Zhang Y, Yang L, Chang C. Interruption of nuclear factor kappaB signaling by the androgen receptor facilitates 12-O-tetradecanoylphorbolacetate-induced apoptosis in androgen-sensitive prostate cancer LNCaP cells. Cancer Research. 63: 7106-12. PMID 14612503 |
0.801 |
|
| 2003 |
Lin HK, Hu YC, Yang L, Altuwaijri S, Chen YT, Kang HY, Chang C. Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers. The Journal of Biological Chemistry. 278: 50902-7. PMID 14555644 DOI: 10.1074/Jbc.M300676200 |
0.855 |
|
| 2003 |
Yang L, Wang L, Lin HK, Kan PY, Xie S, Tsai MY, Wang PH, Chen YT, Chang C. Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells. Biochemical and Biophysical Research Communications. 305: 462-9. PMID 12763015 DOI: 10.1016/S0006-291X(03)00792-7 |
0.807 |
|
| 2003 |
Yang L, Lin HK, Altuwaijri S, Xie S, Wang L, Chang C. APPL suppresses androgen receptor transactivation via potentiating Akt activity. The Journal of Biological Chemistry. 278: 16820-7. PMID 12621049 DOI: 10.1074/Jbc.M213163200 |
0.803 |
|
| 2002 |
Lin HK, Wang L, Hu YC, Altuwaijri S, Chang C. Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase. The Embo Journal. 21: 4037-48. PMID 12145204 DOI: 10.1093/Emboj/Cdf406 |
0.823 |
|
| 2002 |
Lin HK, Altuwaijri S, Lin WJ, Kan PY, Collins LL, Chang C. Proteasome activity is required for androgen receptor transcriptional activity via regulation of androgen receptor nuclear translocation and interaction with coregulators in prostate cancer cells. The Journal of Biological Chemistry. 277: 36570-6. PMID 12119296 DOI: 10.1074/Jbc.M204751200 |
0.861 |
|
| 2001 |
Lin HK, Yeh S, Kang HY, Chang C. Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor. Proceedings of the National Academy of Sciences of the United States of America. 98: 7200-5. PMID 11404460 DOI: 10.1073/Pnas.121173298 |
0.663 |
|
| 2001 |
Kang HY, Lin HK, Hu YC, Yeh S, Huang KE, Chang C. From transforming growth factor-beta signaling to androgen action: identification of Smad3 as an androgen receptor coregulator in prostate cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 3018-23. PMID 11248024 DOI: 10.1073/Pnas.061305498 |
0.785 |
|
| 2000 |
Yeh S, Hu YC, Rahman M, Lin HK, Hsu CL, Ting HJ, Kang HY, Chang C. Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 11256-61. PMID 11016951 DOI: 10.1073/Pnas.190353897 |
0.826 |
|
| 1999 |
Yeh S, Kang HY, Miyamoto H, Nishimura K, Chang HC, Ting HJ, Rahman M, Lin HK, Fujimoto N, Hu YC, Mizokami A, Huang KE, Chang C. Differential induction of androgen receptor transactivation by different androgen receptor coactivators in human prostate cancer DU145 cells. Endocrine. 11: 195-202. PMID 10709768 DOI: 10.1385/Endo:11:2:195 |
0.841 |
|
| 1999 |
Yeh S, Chang HC, Miyamoto H, Takatera H, Rahman M, Kang HY, Thin TH, Lin HK, Chang C. Differential induction of the androgen receptor transcriptional activity by selective androgen receptor coactivators. The Keio Journal of Medicine. 48: 87-92. PMID 10405524 DOI: 10.2302/Kjm.48.87 |
0.806 |
|
| 1999 |
Yeh S, Lin HK, Kang HY, Thin TH, Lin MF, Chang C. From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 5458-63. PMID 10318905 DOI: 10.1073/Pnas.96.10.5458 |
0.716 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2014 |
Feng H, Lopez GY, Kim CK, Alvarez A, Duncan CG, Nishikawa R, Nagane M, Su AJ, Auron PE, Hedberg ML, Wang L, Raizer JJ, Kessler JA, Parsa AT, Gao WQ, ... ... Lin HK, et al. EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis. The Journal of Clinical Investigation. 124: 3741-56. PMID 25061874 DOI: 10.1172/Jci73093 |
0.298 |
|
| 2009 |
Lin HK, Wang G, Chen Z, Teruya-Feldstein J, Liu Y, Chan CH, Yang WL, Erdjument-Bromage H, Nakayama KI, Nimer S, Tempst P, Pandolfi PP. Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. Nature Cell Biology. 11: 420-32. PMID 19270694 DOI: 10.1038/Ncb1849 |
0.296 |
|
| 2022 |
Kant R, Manne RK, Anas M, Penugurti V, Chen T, Pan BS, Hsu CC, Lin HK. Deregulated transcription factors in cancer cell metabolisms and reprogramming. Seminars in Cancer Biology. 86: 1158-1174. PMID 36244530 DOI: 10.1016/j.semcancer.2022.10.001 |
0.295 |
|
| 2011 |
Jane ZY, Chang CC, Lin HK, Liu YC, Chen WL. The association between the exacerbation of irritable bowel syndrome and menstrual symptoms in young Taiwanese women. Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates. 34: 277-86. PMID 21814061 DOI: 10.1097/SGA.0b013e3182248708 |
0.294 |
|
| 2021 |
Hsu CC, Peng D, Cai Z, Lin HK. AMPK signaling and its targeting in cancer progression and treatment. Seminars in Cancer Biology. PMID 33862221 DOI: 10.1016/j.semcancer.2021.04.006 |
0.293 |
|
| 2019 |
Zhang W, Wang G, Xu ZG, Tu H, Hu F, Dai J, Chang Y, Chen Y, Lu Y, Zeng H, Cai Z, Han F, Xu C, Jin G, Sun L, ... ... Lin HK, et al. Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS. Cell. PMID 31155231 DOI: 10.1016/J.Cell.2019.05.003 |
0.291 |
|
| 2014 |
Lin WY, Chang CL, Fu LS, Lin CH, Lin HK. Systemic lupus erythematosus and thyroid disease: A 10-year study. Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi. PMID 24874431 DOI: 10.1016/j.jmii.2014.03.004 |
0.288 |
|
| 2011 |
Chan CH, Gao Y, Moten A, Lin HK. Novel ARF/p53-independent senescence pathways in cancer repression. Journal of Molecular Medicine (Berlin, Germany). 89: 857-67. PMID 21594579 DOI: 10.1007/s00109-011-0766-y |
0.287 |
|
| 2011 |
Hsieh TH, Chen PY, Huang FL, Wang JD, Wang LC, Lin HK, Lin HC, Hsieh HY, Yu MK, Chang CF, Chuang TY, Lee CY. Are empiric antibiotics for acute exudative tonsillitis needed in children? Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi. 44: 328-32. PMID 21524968 DOI: 10.1016/j.jmii.2010.08.009 |
0.283 |
|
| 2020 |
Lei J, Song GT, He LJ, Luo YF, Tang DY, Lin HK, Frett B, Li HY, Chen ZZ, Xu ZG. One-pot construction of functionalized aziridines and maleimides via a novel pseudo-Knoevenagel cascade reaction. Chemical Communications (Cambridge, England). PMID 31971170 DOI: 10.1039/C9Cc08220D |
0.281 |
|
| 2020 |
Kwan SY, Au-Yeung CL, Yeung TL, Rynne-Vidal A, Wong KK, Risinger JI, Lin HK, Schmandt RE, Yates MS, Mok SC, Lu KH. Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Promotes Uterine Serous Cancer Cell Proliferation and Cell Cycle Progression. Cancers. 12. PMID 31906456 DOI: 10.3390/cancers12010118 |
0.279 |
|
| 2010 |
Chan CH, Lee SW, Li CF, Wang J, Yang WL, Wu CY, Wu J, Nakayama KI, Kang HY, Huang HY, Hung MC, Pandolfi PP, Lin HK. Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis. Nature Cell Biology. 12: 457-67. PMID 20383141 DOI: 10.1038/Ncb2047 |
0.277 |
|
| 2014 |
Thirumurthi U, Shen J, Xia W, LaBaff AM, Wei Y, Li CW, Chang WC, Chen CH, Lin HK, Yu D, Hung MC. MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer. Science Signaling. 7: ra71. PMID 25074979 DOI: 10.1126/Scisignal.2005076 |
0.272 |
|
| 2012 |
Tsai WB, Aiba I, Long Y, Lin HK, Feun L, Savaraj N, Kuo MT. Activation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells. Cancer Research. 72: 2622-33. PMID 22461507 DOI: 10.1158/0008-5472.Can-11-3605 |
0.271 |
|
| 2018 |
He LJ, Yang DL, Li SQ, Zhang YJ, Tang Y, Lei J, Frett B, Lin HK, Li HY, Chen ZZ, Xu ZG. Facile construction of fused benzimidazole-isoquinolinones that induce cell-cycle arrest and apoptosis in colorectal cancer cells. Bioorganic & Medicinal Chemistry. PMID 29921474 DOI: 10.1016/j.bmc.2018.06.010 |
0.269 |
|
| 2015 |
Xu D, Li CF, Zhang X, Gong Z, Chan CH, Lee SW, Jin G, Rezaeian AH, Han F, Wang J, Yang WL, Feng ZZ, Chen W, Wu CY, Wang YJ, ... ... Lin HK, et al. Skp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis. Nature Communications. 6: 6641. PMID 25818643 DOI: 10.1038/ncomms7641 |
0.268 |
|
| 2020 |
Liu C, Ma Z, Cai Z, Zhang F, Liu C, Chen T, Peng D, Xu X, Lin HK. Identification of primordial germ cell-like cells as liver metastasis initiating cells in mouse tumour models. Cell Discovery. 6: 15. PMID 32218989 DOI: 10.1038/S41421-020-0145-3 |
0.267 |
|
| 2015 |
Lee SW, Li CF, Jin G, Cai Z, Han F, Chan CH, Yang WL, Li BK, Rezaeian AH, Li HY, Huang HY, Lin HK. Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress. Molecular Cell. 57: 1022-33. PMID 25728766 DOI: 10.1016/j.molcel.2015.01.015 |
0.264 |
|
| 2022 |
Yang DL, Zhang YJ, Lei J, Li SQ, He LJ, Tang DY, Xu C, Zhang LT, Wen J, Lin HK, Li HY, Chen ZZ, Xu ZG. Discovery of fused benzimidazole-imidazole autophagic flux inhibitors for treatment of triple-negative breast cancer. European Journal of Medicinal Chemistry. 240: 114565. PMID 35797901 DOI: 10.1016/j.ejmech.2022.114565 |
0.257 |
|
| 2009 |
Liu Y, Liu F, Zhao X, Sashida G, Deblasio A, Chen Z, Lin H, Di Giandomenico S, Elf S, Yang Y, Miyata Y, Huang G, Menendez S, Mellinghoff I, Pandolfi PP, et al. Akt-Mediated Phosphorylation of Bmi1 Regulates Its Chromatin Association and Growth Promoting Properties. Blood. 114: 3605-3605. DOI: 10.1182/Blood.V114.22.3605.3605 |
0.256 |
|
| 2005 |
Lin HK, Bergmann S, Pandolfi PP. Deregulated TGF-beta signaling in leukemogenesis. Oncogene. 24: 5693-700. PMID 16123802 DOI: 10.1038/Sj.Onc.1208923 |
0.251 |
|
| 2020 |
Wang G, Wang J, Chang A, Cheng D, Huang S, Wu D, Sirkisoon S, Yang S, Lin HK, Lo HW, Xiang R, Sun P. Her2 promotes early dissemination of breast cancer by suppressing the p38 pathway through Skp2-mediated proteasomal degradation of Tpl2. Oncogene. PMID 32989258 DOI: 10.1038/s41388-020-01481-y |
0.25 |
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| 2017 |
Wu CY, Cherng JY, Yang YH, Lin CL, Kuan FC, Lin YY, Lin YS, Shu LH, Cheng YC, Liu HT, Lu MC, Lung J, Chen PC, Lin HK, Lee KD, et al. Danshen improves survival of patients with advanced lung cancer and targeting the relationship between macrophages and lung cancer cells. Oncotarget. 8: 90925-90947. PMID 29207614 DOI: 10.18632/oncotarget.18767 |
0.249 |
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| 2017 |
Wu CY, Cherng JY, Yang YH, Lin CL, Kuan FC, Lin YY, Lin YS, Shu LH, Cheng YC, Liu HT, Lu MC, Lung J, Chen PC, Lin HK, Lee KD, et al. Danshen improves survival of patients with advanced lung cancer and targeting the relationship between macrophages and lung cancer cells. Oncotarget. PMID 28678759 DOI: 10.18632/oncotarget.18767 |
0.249 |
|
| 2015 |
Morrow JK, Lin HK, Sun SC, Zhang S. Targeting ubiquitination for cancer therapies. Future Medicinal Chemistry. PMID 26630263 DOI: 10.4155/fmc.15.148 |
0.245 |
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| 2022 |
Xu C, Jin G, Wu H, Cui W, Wang YH, Manne RK, Wang G, Zhang W, Zhang X, Han F, Cai Z, Pan BS, Hsu CC, Liu Y, Zhang A, ... ... Lin HK, et al. SIRPγ-expressing cancer stem-like cells promote immune escape of lung cancer via Hippo signaling. The Journal of Clinical Investigation. 132. PMID 35229723 DOI: 10.1172/JCI141797 |
0.245 |
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| 2015 |
Chen L, Du-Cuny L, Moses S, Dumas S, Song Z, Rezaeian AH, Lin HK, Meuillet EJ, Zhang S. Novel inhibitors induce large conformational changes of GAB1 pleckstrin homology domain and kill breast cancer cells. Plos Computational Biology. 11: e1004021. PMID 25569504 DOI: 10.1371/Journal.Pcbi.1004021 |
0.244 |
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| 2012 |
Liu Y, Liu F, Yu H, Zhao X, Sashida G, Deblasio A, Harr M, She QB, Chen Z, Lin HK, Di Giandomenico S, Elf SE, Yang Y, Miyata Y, Huang G, et al. Akt phosphorylates the transcriptional repressor Bmi1 to block its effects on the tumor-suppressing Ink4a-Arf locus Science Signaling. 5. PMID 23092893 DOI: 10.1126/Scisignal.2003199 |
0.243 |
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| 2023 |
Zhu GF, Xu YW, Li J, Niu HL, Ma WX, Xu J, Zhou PR, Liu X, Ye DL, Liu XR, Yan T, Zhai WK, Xu ZJ, Liu C, Wang L, ... ... Lin HK, et al. Retraction Note: Mir20a/106a-WTX axis regulates RhoGDIa/CDC42 signaling and colon cancer progression. Nature Communications. 14: 5772. PMID 37723148 DOI: 10.1038/s41467-023-41612-z |
0.242 |
|
| 2011 |
Tao RH, Berkova Z, Wise JF, Rezaeian AH, Daniluk U, Ao X, Hawke DH, Karp JE, Lin HK, Molldrem JJ, Samaniego F. PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo. Blood. 118: 3107-18. PMID 21803845 DOI: 10.1182/blood-2011-04-349670 |
0.241 |
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| 2009 |
Yang WL, Wang J, Chan CH, Lee SW, Campos AD, Lamothe B, Hur L, Grabiner BC, Lin X, Darnay BG, Lin HK. The E3 ligase TRAF6 regulates Akt ubiquitination and activation. Science (New York, N.Y.). 325: 1134-8. PMID 19713527 DOI: 10.1126/science.1175065 |
0.238 |
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| 2022 |
Xu C, Wu H, Liu Y, Li F, Manne RK, Lin HK. Protocol for detecting macrophage-mediated cancer cell phagocytosis in vitro and in vivo. Star Protocols. 4: 101940. PMID 36520628 DOI: 10.1016/j.xpro.2022.101940 |
0.234 |
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| 2014 |
Kim JH, Sharma A, Dhar SS, Lee SH, Gu B, Chan CH, Lin HK, Lee MG. UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells. Cancer Research. 74: 1705-17. PMID 24491801 DOI: 10.1158/0008-5472.Can-13-1896 |
0.231 |
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| 2021 |
Wang G, Wang J, Chang A, Cheng D, Huang S, Wu D, Sirkisoon S, Yang S, Lin HK, Lo HW, Xiang R, Sun P. Correction to: Her2 promotes early dissemination of breast cancer by suppressing the p38 pathway through Skp2-mediated proteasomal degradation of Tpl2. Oncogene. PMID 33568787 DOI: 10.1038/s41388-021-01652-5 |
0.23 |
|
| 2012 |
Chen D, Sun Y, Wei Y, Zhang P, Rezaeian AH, Teruya-Feldstein J, Gupta S, Liang H, Lin HK, Hung MC, Ma L. LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker. Nature Medicine. 18: 1511-7. PMID 23001183 DOI: 10.1038/Nm.2940 |
0.229 |
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| 2022 |
Agyemang K, Johansen AM, Barker GW, Pennison MJ, Sheffield K, Jimenez H, Blackman C, Sharma S, Fordjour PA, Singh R, Cook KL, Lin HK, Zhang W, Lo HW, Watabe K, et al. TGFBR1*6A as a modifier of breast cancer risk and progression: advances and future prospects. Npj Breast Cancer. 8: 84. PMID 35853889 DOI: 10.1038/s41523-022-00446-6 |
0.227 |
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| 2010 |
Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Chan CH, Yang WL, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP. Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. Nature. 464: 374-9. PMID 20237562 DOI: 10.1038/Nature08815 |
0.221 |
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| 2012 |
Lamothe B, Lai Y, Hur L, Orozco NM, Wang J, Campos AD, Xie M, Schneider MD, Lockworth CR, Jakacky J, Tran D, Ho M, Dawud S, Dong C, Lin HK, et al. Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice. Plos One. 7: e51228. PMID 23251462 DOI: 10.1371/journal.pone.0051228 |
0.209 |
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| 2021 |
Li W, Li F, Zhang X, Lin H, Xu C. Insights into the post-translational modification and its emerging role in shaping the tumor microenvironment. Signal Transduction and Targeted Therapy. 6: 422. PMID 34924561 DOI: 10.1038/s41392-021-00825-8 |
0.203 |
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| 2017 |
Geng Q, Liu J, Gong Z, Chen S, Chen S, Li X, Lu Y, Zhu X, Lin HK, Xu D. Phosphorylation by mTORC1 stablizes Skp2 and regulates its oncogenic function in gastric cancer. Molecular Cancer. 16: 83. PMID 28446188 DOI: 10.1186/s12943-017-0649-0 |
0.2 |
|
| 2004 |
Lin HK, Bergmann S, Pandolfi PP. Cytoplasmic PML function in TGF-beta signalling. Nature. 431: 205-11. PMID 15356634 DOI: 10.1038/nature02783 |
0.2 |
|
| 2011 |
Chen CH, Shaikenov T, Peterson TR, Aimbetov R, Bissenbaev AK, Lee SW, Wu J, Lin HK, Sarbassov dos D. ER stress inhibits mTORC2 and Akt signaling through GSK-3β-mediated phosphorylation of rictor. Science Signaling. 4: ra10. PMID 21343617 DOI: 10.1126/scisignal.2001731 |
0.199 |
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| 2022 |
Rimkus TK, Arrigo AB, Zhu D, Carpenter RL, Sirkisoon S, Doheny D, Regua AT, Wong GL, Manore S, Wagner C, Lin HK, Jin G, Ruiz J, Chan M, Debinski W, et al. NEDD4 degrades TUSC2 to promote glioblastoma progression. Cancer Letters. 531: 124-135. PMID 35167936 DOI: 10.1016/j.canlet.2022.01.029 |
0.198 |
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| 2019 |
Jimenez H, Wang M, Zimmerman JW, Pennison MJ, Sharma S, Surratt T, Xu ZX, Brezovich I, Absher D, Myers RM, DeYoung B, Caudell DL, Chen D, Lo HW, Lin HK, et al. Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Ca3.2 T-type voltage-gated calcium channels and Ca influx. Ebiomedicine. PMID 31160272 DOI: 10.1016/J.Ebiom.2019.05.034 |
0.198 |
|
| 2019 |
Wang G, Long J, Gao Y, Zhang W, Han F, Xu C, Sun L, Yang SC, Lan J, Hou Z, Cai Z, Jin G, Hsu CC, Wang YH, Hu J, ... ... Lin HK, et al. SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis. Nature Cell Biology. PMID 30692626 DOI: 10.1038/s41556-018-0266-1 |
0.197 |
|
| 2020 |
Lei J, Li Y, He L, Luo Y, Tang D, Yan W, Lin H, Li H, Chen Z, Xu Z. Expeditious access of chromone analogues via a Michael addition-driven multicomponent reaction Organic Chemistry Frontiers. 7: 987-992. DOI: 10.1039/D0Qo00145G |
0.195 |
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| 2010 |
Giorgi C, Ito K, Lin HK, Santangelo C, Wieckowski MR, Lebiedzinska M, Bononi A, Bonora M, Duszynski J, Bernardi R, Rizzuto R, Tacchetti C, Pinton P, Pandolfi PP. PML regulates apoptosis at endoplasmic reticulum by modulating calcium release. Science (New York, N.Y.). 330: 1247-51. PMID 21030605 DOI: 10.1126/Science.1189157 |
0.195 |
|
| 2013 |
Song S, Maru DM, Ajani JA, Chan CH, Honjo S, Lin HK, Correa A, Hofstetter WL, Davila M, Stroehlein J, Mishra L. Loss of TGF-β adaptor β2SP activates notch signaling and SOX9 expression in esophageal adenocarcinoma. Cancer Research. 73: 2159-69. PMID 23536563 DOI: 10.1158/0008-5472.CAN-12-1962 |
0.194 |
|
| 2015 |
Gong L, Govan JM, Evans EB, Dai H, Wang E, Lee SW, Lin HK, Lazar AJ, Mills GB, Lin SY. Nuclear PTEN Tumor-Suppressor Functions Through Maintaining Heterochromatin Structure. Cell Cycle (Georgetown, Tex.). 0. PMID 25946202 DOI: 10.1080/15384101.2015.1044174 |
0.194 |
|
| 2014 |
Chan CH, Morrow JK, Zhang S, Lin HK. Skp2: a dream target in the coming age of cancer therapy. Cell Cycle (Georgetown, Tex.). 13: 679-80. PMID 24526126 DOI: 10.4161/cc.27853 |
0.191 |
|
| 2013 |
Jin G, Wang YJ, Lin HK. Emerging Cellular Functions of Cytoplasmic PML. Frontiers in Oncology. 3: 147. PMID 23761861 DOI: 10.3389/fonc.2013.00147 |
0.19 |
|
| 2014 |
Gong Z, Yang J, Li J, Yang L, Le Y, Wang S, Lin HK. Novel insights into the role of microRNA in lung cancer resistance to treatment and targeted therapy. Current Cancer Drug Targets. 14: 241-58. PMID 24605945 |
0.188 |
|
| 2013 |
Wagner KW, Alam H, Dhar SS, Giri U, Li N, Wei Y, Giri D, Cascone T, Kim JH, Ye Y, Multani AS, Chan CH, Erez B, Saigal B, Chung J, ... Lin HK, et al. KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling. The Journal of Clinical Investigation. 123: 5231-46. PMID 24200691 DOI: 10.1172/Jci68642 |
0.187 |
|
| 2014 |
Wang J, Han F, Lee SW, Wu J, Chan CH, Zhang X, Gao Y, Su HK, Feng ZZ, Xu DZ, Lin HK. E3-ligase Skp2 regulates β-catenin expression and maintains hematopoietic stem cell homing. Biochemical and Biophysical Research Communications. 445: 566-71. PMID 24561244 DOI: 10.1016/j.bbrc.2014.02.042 |
0.186 |
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| 2015 |
Jin G, Lee SW, Zhang X, Cai Z, Gao Y, Chou PC, Rezaeian AH, Han F, Wang CY, Yao JC, Gong Z, Chan CH, Huang CY, Tsai FJ, Tsai CH, ... ... Lin HK, et al. Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1. Molecular Cell. 58: 989-1000. PMID 26051179 DOI: 10.1016/j.molcel.2015.05.010 |
0.182 |
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| 2016 |
Liu X, Xiao ZD, Han L, Zhang J, Lee SW, Wang W, Lee H, Zhuang L, Chen J, Lin HK, Wang J, Liang H, Gan B. LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress. Nature Cell Biology. PMID 26999735 DOI: 10.1038/Ncb3328 |
0.181 |
|
| 2013 |
Rezaeian AH, Gao Y, Lin HK. Cloning, expression, and functional analysis of genomic miRNA using retroviral system in cancer cells. Methods in Molecular Biology (Clifton, N.J.). 936: 157-72. PMID 23007507 DOI: 10.1007/978-1-62703-083-0_13 |
0.18 |
|
| 2015 |
Li J, Yang J, Zhou P, Le Y, Zhou C, Wang S, Xu D, Lin HK, Gong Z. Circular RNAs in cancer: novel insights into origins, properties, functions and implications. American Journal of Cancer Research. 5: 472-80. PMID 25973291 |
0.18 |
|
| 2021 |
Liu C, Moten A, Ma Z, Lin HK. The Foundational Framework of Tumors: Gametogenesis, p53, and Cancer. Seminars in Cancer Biology. PMID 33940178 DOI: 10.1016/j.semcancer.2021.04.018 |
0.18 |
|
| 2011 |
Wang J, Han F, Wu J, Lee SW, Chan CH, Wu CY, Yang WL, Gao Y, Zhang X, Jeong YS, Moten A, Samaniego F, Huang P, Liu Q, Zeng YX, ... Lin HK, et al. The role of Skp2 in hematopoietic stem cell quiescence, pool size, and self-renewal. Blood. 118: 5429-38. PMID 21931116 DOI: 10.1182/blood-2010-10-312785 |
0.18 |
|
| 2023 |
Leu SY, Tsang YL, Ho LC, Yang CC, Shao AN, Chang CY, Lin HK, Tsai PJ, Sung JM, Tsai YS. NLRP3 inflammasome activation, metabolic danger signals and protein binding partners. The Journal of Endocrinology. PMID 36799299 DOI: 10.1530/JOE-22-0184 |
0.177 |
|
| 2014 |
Jin G, Gao Y, Lin HK. Cytoplasmic PML: from molecular regulation to biological functions. Journal of Cellular Biochemistry. 115: 812-8. PMID 24288198 DOI: 10.1002/jcb.24727 |
0.171 |
|
| 2014 |
Gao Y, Moten A, Lin HK. Akt: a new activation mechanism. Cell Research. 24: 785-6. PMID 24797432 DOI: 10.1038/cr.2014.57 |
0.167 |
|
| 2017 |
Zhang X, Li B, Rezaeian AH, Xu X, Chou PC, Jin G, Han F, Pan BS, Wang CY, Long J, Zhang A, Huang CY, Tsai FJ, Tsai CH, Logothetis C, ... Lin HK, et al. H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis. Nature Communications. 8: 14799. PMID 28300060 DOI: 10.1038/ncomms14799 |
0.164 |
|
| 2013 |
Qiu Q, Zheng Z, Chang L, Zhao YS, Tan C, Dandekar A, Zhang Z, Lin Z, Gui M, Li X, Zhang T, Kong Q, Li H, Chen S, Chen A, ... ... Lin HK, et al. Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis. The Embo Journal. 32: 2477-90. PMID 23942232 DOI: 10.1038/Emboj.2013.183 |
0.161 |
|
| 2018 |
Jin G, Xu C, Zhang X, Long J, Rezaeian AH, Liu C, Furth ME, Kridel S, Pasche B, Bian XW, Lin HK. Atad3a suppresses Pink1-dependent mitophagy to maintain homeostasis of hematopoietic progenitor cells. Nature Immunology. 19: 29-40. PMID 29242539 DOI: 10.1038/S41590-017-0002-1 |
0.16 |
|
| 2015 |
Parameswaran B, Chiang HC, Lu Y, Coates J, Deng CX, Baer R, Lin HK, Li R, Paull TT, Hu Y. Damage-induced BRCA1 phosphorylation by Chk2 contributes to the timing of end resection. Cell Cycle (Georgetown, Tex.). 14: 437-48. PMID 25659039 DOI: 10.4161/15384101.2014.972901 |
0.16 |
|
| 2023 |
Meyers AK, Wang Z, Han W, Zhao Q, Zabalawi M, Duan L, Liu J, Zhang Q, Manne RK, Lorenzo F, Quinn MA, Song Q, Fan D, Lin HK, Furdui CM, et al. Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation. Cell Reports. 42: 111941. PMID 36640341 DOI: 10.1016/j.celrep.2022.111941 |
0.158 |
|
| 2019 |
Zhu GF, Xu YW, Li J, Niu HL, Ma WX, Xu J, Zhou PR, Liu X, Ye DL, Liu XR, Yan T, Zhai WK, Xu ZJ, Liu C, Wang L, ... ... Lin HK, et al. Mir20a/106a-WTX axis regulates RhoGDIa/CDC42 signaling and colon cancer progression. Nature Communications. 10: 112. PMID 30631060 DOI: 10.1038/s41467-018-07998-x |
0.157 |
|
| 2023 |
Liu Z, Villareal L, Goodla L, Kim H, Falcon DM, Haneef M, Martin DR, Zhang L, Lee HJ, Kremer D, Lyssiotis CA, Shah YM, Lin HC, Lin HK, Xue X. Iron promotes glycolysis to drive colon tumorigenesis. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 166846. PMID 37579983 DOI: 10.1016/j.bbadis.2023.166846 |
0.151 |
|
| 2015 |
Wu J, Huang YF, Zhou XK, Zhang W, Lian YF, Lv XB, Gao XR, Lin HK, Zeng YX, Huang JQ. Skp2 is required for Aurora B activation in cell mitosis and spindle checkpoint. Cell Cycle (Georgetown, Tex.). 14: 3877-84. PMID 26697838 DOI: 10.1080/15384101.2015.1120916 |
0.149 |
|
| 2017 |
Li CH, Yen CH, Chen YF, Lee KJ, Fang CC, Zhang X, Lai CC, Huang SF, Lin HK, Arthur Chen YM. Characterization of the GNMT-HectH9-PREX2 Tripartite Relationship in the Pathogenesis of Hepatocellular Carcinoma. International Journal of Cancer. PMID 28205209 DOI: 10.1002/ijc.30652 |
0.144 |
|
| 2016 |
Zhang X, Li CF, Zhang L, Wu CY, Han L, Jin G, Rezaeian AH, Han F, Liu C, Xu C, Xu X, Huang CY, Tsai FJ, Tsai CH, Watabe K, ... Lin HK, et al. TRAF6 Restricts p53 Mitochondrial Translocation, Apoptosis, and Tumor Suppression. Molecular Cell. PMID 27818144 DOI: 10.1016/J.Molcel.2016.10.002 |
0.141 |
|
| 2022 |
Fong LWR, Lee J, Lin HK, Ueno NT, Zhang S. A gene signature consisting of ubiquitin ligases and deubiquitinating enzymes of SKP2 is associated with clinical outcome in breast cancer. Scientific Reports. 12: 2478. PMID 35169199 DOI: 10.1038/s41598-022-06451-w |
0.14 |
|
| 2012 |
Chan CH, Li CF, Yang WL, Gao Y, Lee SW, Feng Z, Huang HY, Tsai KKC, Flores LG, Shao Y, Hazle JD, Yu D, Wei W, Sarbassov D, Hung MC, ... ... Lin HK, et al. The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis. Cell. 151: 913-914. PMID 30360292 DOI: 10.1016/J.Cell.2012.10.025 |
0.139 |
|
| 2006 |
Shen TH, Lin HK, Scaglioni PP, Yung TM, Pandolfi PP. The mechanisms of PML-nuclear body formation. Molecular Cell. 24: 331-9. PMID 17081985 DOI: 10.1016/J.Molcel.2006.09.013 |
0.132 |
|
| 2018 |
Xu ZG, Li SQ, Meng JP, Tang DY, He LJ, Lei J, Lin HK, Li HY, Chen ZZ. Functionalized Spiroindolines with Anticancer Activity through a Metal-Free Post-Ugi Diastereoselective One-Pot Cascade Reaction. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29676029 DOI: 10.1002/chem.201801081 |
0.129 |
|
| 2020 |
Liu C, Ma Z, Cai Z, Zhang F, Liu C, Chen T, Peng D, Xu X, Lin HK. Identification of primordial germ cell-like cells as liver metastasis initiating cells in mouse tumour models. Cell Discovery. 6: 15. PMID 33758163 DOI: 10.1038/s41421-020-0145-3 |
0.126 |
|
| 2023 |
Ho LC, Chen YH, Wu TY, Kao LZ, Hung SY, Liou HH, Chen PC, Tsai PJ, Lin HK, Lee YC, Wang HH, Tsai YS. Phosphate burden induces vascular calcification through a NLRP3-caspase-1-mediated pyroptotic pathway. Life Sciences. 332: 122123. PMID 37742736 DOI: 10.1016/j.lfs.2023.122123 |
0.126 |
|
| 2022 |
Ma Z, Zhang F, Xiong J, Zhang H, Lin HK, Liu C. Activation of embryonic/germ cell-like axis links poor outcomes of gliomas. Cancer Cell International. 22: 371. PMID 36435765 DOI: 10.1186/s12935-022-02792-8 |
0.123 |
|
| 2023 |
Chen T, Xu ZG, Luo J, Manne RK, Wang Z, Hsu CC, Pan BS, Cai Z, Tsai PJ, Tsai YS, Chen ZZ, Li HY, Lin HK. NSUN2 is a glucose sensor suppressing cGAS/STING to maintain tumorigenesis and immunotherapy resistance. Cell Metabolism. PMID 37586363 DOI: 10.1016/j.cmet.2023.07.009 |
0.118 |
|
| 2020 |
Rezaeian AH, Li CF, Wu CY, Zhang X, Delacerda J, You MJ, Han F, Cai Z, Jeong YS, Jin G, Phan L, Chou PC, Lee MH, Hung MC, Sarbassov D, ... Lin HK, et al. Author Correction: A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis. Nature Cell Biology. PMID 32504031 DOI: 10.1038/s41556-020-0538-4 |
0.111 |
|
| 2022 |
Chang YS, Hou SY, Yu SS, Tsai SY, Chen YY, Hsu LJ, Tsai PJ, Lin HK, Lin CH, Tsai YS. Postnatal Dexamethasone Therapy Impairs Brown Adipose Tissue Thermogenesis and Autophagy Flux in Neonatal Rat Pups. Theranostics. 12: 5803-5819. PMID 35966581 DOI: 10.7150/thno.70752 |
0.107 |
|
| 2022 |
Hsu CC, Xu ZG, Lei J, Chen ZZ, Li HY, Lin HK. Identification of myo-inositol-binding proteins by using the biotin pull-down strategy in cultured cells. Star Protocols. 3: 101385. PMID 35600928 DOI: 10.1016/j.xpro.2022.101385 |
0.099 |
|
| 2012 |
Wu J, Zhang X, Zhang L, Wu CY, Rezaeian AH, Chan CH, Li JM, Wang J, Gao Y, Han F, Jeong YS, Yuan X, Khanna KK, Jin J, Zeng YX, ... Lin HK, et al. Skp2 E3 ligase integrates ATM activation and homologous recombination repair by ubiquitinating NBS1. Molecular Cell. 46: 351-61. PMID 22464731 DOI: 10.1016/J.Molcel.2012.02.018 |
0.098 |
|
| 2011 |
Wu CY, Kang HY, Yang WL, Wu J, Jeong YS, Wang J, Chan CH, Lee SW, Zhang X, Lamothe B, Campos AD, Darnay BG, Lin HK. Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response. The Journal of Biological Chemistry. 286: 30806-15. PMID 21690091 DOI: 10.1074/jbc.M111.257469 |
0.098 |
|
| 2022 |
Yan W, Pan BS, Shao J, Lin HK, Li HY. Feasible Column Chromatography-Free, Multi-Gram Scale Synthetic Process of VH032 Amine, Which Could Enable Rapid PROTAC Library Construction. Acs Omega. 7: 26015-26020. PMID 35936457 DOI: 10.1021/acsomega.2c00245 |
0.097 |
|
| 2021 |
Hsu CC, Tsai YS, Lin HK. UHRF1: a novel metabolic guardian restricting AMPK activity. Cell Research. PMID 34907338 DOI: 10.1038/s41422-021-00589-4 |
0.088 |
|
| 2021 |
Wang G, Long J, Gao Y, Zhang W, Han F, Xu C, Sun L, Yang SC, Lan J, Hou Z, Cai Z, Jin G, Hsu CC, Wang YH, Hu J, ... ... Lin HK, et al. Author Correction: SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis. Nature Cell Biology. PMID 33927372 DOI: 10.1038/s41556-021-00686-x |
0.088 |
|
| 2021 |
Hsu CC, Zhang X, Wang G, Zhang W, Cai Z, Pan BS, Gu H, Xu C, Jin G, Xu X, Manne RK, Jin Y, Yan W, Shao J, Chen T, ... ... Lin HK, et al. Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK. Molecular Cell. 81: 3803-3819.e7. PMID 34547240 DOI: 10.1016/j.molcel.2021.08.025 |
0.08 |
|
| 2017 |
Rezaeian AH, Wang YH, Lin HK. DNA damage players are linked to HIF-1α/hypoxia signaling. Cell Cycle (Georgetown, Tex.). 0. PMID 28282267 DOI: 10.1080/15384101.2017.1302208 |
0.07 |
|
| 2020 |
Lei J, Song GT, He LJ, Luo YF, Tang DY, Lin HK, Frett B, Li HY, Chen ZZ, Xu ZG. Correction: One-pot construction of functionalized aziridines and maleimides via a novel pseudo-Knoevenagel cascade reaction. Chemical Communications (Cambridge, England). PMID 32031562 DOI: 10.1039/d0cc90063j |
0.07 |
|
| 2022 |
Li W, Li F, Zhang X, Lin HK, Xu C. Correction: Insights into the post-translational modification and its emerging role in shaping the tumor microenvironment. Signal Transduction and Targeted Therapy. 7: 31. PMID 35095101 DOI: 10.1038/s41392-022-00901-7 |
0.06 |
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| 2022 |
Lyu Q, Namjoshi SV, McTyre E, Topaloglu U, Barcus R, Chan MD, Cramer CK, Debinski W, Gurcan MN, Lesser GJ, Lin HK, Munden RF, Pasche BC, Sai KKS, Strowd RE, et al. A transformer-based deep-learning approach for classifying brain metastases into primary organ sites using clinical whole-brain MRI images. Patterns (New York, N.Y.). 3: 100613. PMID 36419451 DOI: 10.1016/j.patter.2022.100613 |
0.055 |
|
| 2024 |
Chen T, Lin HK. Protocol to analyze the role of various metabolites in impacting global RNA 5-methylcytosine levels in cultured cells by dot blot. Star Protocols. 5: 102815. PMID 38180832 DOI: 10.1016/j.xpro.2023.102815 |
0.054 |
|
| 2006 |
Shen TH, Lin HK, Scaglioni PP, Yung TM, Pandolfi PP. The Mechanisms of PML-Nuclear Body Formation. Molecular Cell. 24: 805. PMID 29654784 DOI: 10.1016/J.Molcel.2006.11.010 |
0.052 |
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