Kuo-Pao Lai, Ph.D. - Publications

Affiliations: 
2010 University of Rochester, Rochester, NY 
Area:
Endocrinology Biology, Human Development, Molecular Biology

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Huang CK, Luo J, Lai KP, Wang R, Pang H, Chang E, Yan C, Sparks J, Lee SO, Cho J, Chang C. Androgen Receptor Promotes Abdominal Aortic Aneurysm Development via Modulating Inflammatory Interleukin-1α and Transforming Growth Factor-β1 Expression. Hypertension. PMID 26324502 DOI: 10.1161/HYPERTENSIONAHA.115.05654  0.4
2014 Shang Z, Niu Y, Cai Q, Chen J, Tian J, Yeh S, Lai KP, Chang C. Human kallikrein 2 (KLK2) promotes prostate cancer cell growth via function as a modulator to promote the ARA70-enhanced androgen receptor transactivation. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 35: 1881-90. PMID 24122203 DOI: 10.1007/s13277-013-1253-6  0.76
2013 Lai KP, Huang CK, Fang LY, Izumi K, Lo CW, Wood R, Kindblom J, Yeh S, Chang C. Targeting stromal androgen receptor suppresses prolactin-driven benign prostatic hyperplasia (BPH). Molecular Endocrinology (Baltimore, Md.). 27: 1617-31. PMID 23893956 DOI: 10.1210/me.2013-1207  0.4
2013 Fang LY, Izumi K, Lai KP, Liang L, Li L, Miyamoto H, Lin WJ, Chang C. Infiltrating macrophages promote prostate tumorigenesis via modulating androgen receptor-mediated CCL4-STAT3 signaling. Cancer Research. 73: 5633-46. PMID 23878190 DOI: 10.1158/0008-5472.CAN-12-3228  0.76
2013 Huang CK, Lai KP, Luo J, Tsai MY, Kang HY, Chen Y, Lee SO, Chang C. Loss of androgen receptor promotes adipogenesis but suppresses osteogenesis in bone marrow stromal cells. Stem Cell Research. 11: 938-50. PMID 23859805 DOI: 10.1016/j.scr.2013.06.001  0.76
2013 Izumi K, Mizokami A, Lin WJ, Lai KP, Chang C. Androgen receptor roles in the development of benign prostate hyperplasia. The American Journal of Pathology. 182: 1942-9. PMID 23570837 DOI: 10.1016/j.ajpath.2013.02.028  0.76
2013 Lai KP, Lai JJ, Chang P, Altuwaijri S, Hsu JW, Chuang KH, Shyr CR, Yeh S, Chang C. Targeting thymic epithelia AR enhances T-cell reconstitution and bone marrow transplant grafting efficacy. Molecular Endocrinology (Baltimore, Md.). 27: 25-37. PMID 23250486 DOI: 10.1210/me.2012-1244  0.76
2013 Lai KP, Huang CK, Chang YJ, Chung CY, Yamashita S, Li L, Lee SO, Yeh S, Chang C. New therapeutic approach to suppress castration-resistant prostate cancer using ASC-J9 via targeting androgen receptor in selective prostate cells. The American Journal of Pathology. 182: 460-73. PMID 23219429 DOI: 10.1016/j.ajpath.2012.10.029  0.76
2013 Huang CK, Lee SO, Lai KP, Ma WL, Lin TH, Tsai MY, Luo J, Chang C. Targeting androgen receptor in bone marrow mesenchymal stem cells leads to better transplantation therapy efficacy in liver cirrhosis. Hepatology (Baltimore, Md.). 57: 1550-63. PMID 23150236 DOI: 10.1002/hep.26135  0.4
2013 Lee SO, Ma Z, Yeh CR, Luo J, Lin TH, Lai KP, Yamashita S, Liang L, Tian J, Li L, Jiang Q, Huang CK, Niu Y, Yeh S, Chang C. New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells. Journal of Molecular Cell Biology. 5: 14-26. PMID 22831834 DOI: 10.1093/jmcb/mjs042  0.76
2012 Lai JJ, Lai KP, Zeng W, Chuang KH, Altuwaijri S, Chang C. Androgen receptor influences on body defense system via modulation of innate and adaptive immune systems: lessons from conditional AR knockout mice. The American Journal of Pathology. 181: 1504-12. PMID 22959669 DOI: 10.1016/j.ajpath.2012.07.008  0.76
2012 Lai JJ, Chang P, Lai KP, Chen L, Chang C. The role of androgen and androgen receptor in skin-related disorders. Archives of Dermatological Research. 304: 499-510. PMID 22829074 DOI: 10.1007/s00403-012-1265-x  0.76
2012 Lai KP, Yamashita S, Huang CK, Yeh S, Chang C. Loss of stromal androgen receptor leads to suppressed prostate tumourigenesis via modulation of pro-inflammatory cytokines/chemokines. Embo Molecular Medicine. 4: 791-807. PMID 22745041 DOI: 10.1002/emmm.201101140  0.76
2012 Wang X, Lin WJ, Izumi K, Jiang Q, Lai KP, Xu D, Fang LY, Lu T, Li L, Xia S, Chang C. Increased infiltrated macrophages in benign prostatic hyperplasia (BPH): role of stromal androgen receptor in macrophage-induced prostate stromal cell proliferation. The Journal of Biological Chemistry. 287: 18376-85. PMID 22474290 DOI: 10.1074/jbc.M112.355164  0.76
2012 Lee SO, Tian J, Huang CK, Ma Z, Lai KP, Hsiao H, Jiang M, Yeh S, Chang C. Suppressor role of androgen receptor in proliferation of prostate basal epithelial and progenitor cells. The Journal of Endocrinology. 213: 173-82. PMID 22393245 DOI: 10.1530/JOE-11-0474  0.76
2012 Yamashita S, Lai KP, Chuang KL, Xu D, Miyamoto H, Tochigi T, Pang ST, Li L, Arai Y, Kung HJ, Yeh S, Chang C. ASC-J9 suppresses castration-resistant prostate cancer growth through degradation of full-length and splice variant androgen receptors. Neoplasia (New York, N.Y.). 14: 74-83. PMID 22355276  0.76
2012 Lai KP, Yamashita S, Vitkus S, Shyr CR, Yeh S, Chang C. Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptor. Molecular Endocrinology (Baltimore, Md.). 26: 52-66. PMID 22135068 DOI: 10.1210/me.2011-1189  0.76
2011 Yu S, Zhang C, Lin CC, Niu Y, Lai KP, Chang HC, Yeh SD, Chang C, Yeh S. Altered prostate epithelial development and IGF-1 signal in mice lacking the androgen receptor in stromal smooth muscle cells. The Prostate. 71: 517-24. PMID 20945497 DOI: 10.1002/pros.21264  0.76
2009 Lai JJ, Lai KP, Chuang KH, Chang P, Yu IC, Lin WJ, Chang C. Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-alpha expression. The Journal of Clinical Investigation. 119: 3739-51. PMID 19907077 DOI: 10.1172/JCI39335  0.76
2009 Chuang KH, Altuwaijri S, Li G, Lai JJ, Chu CY, Lai KP, Lin HY, Hsu JW, Keng P, Wu MC, Chang C. Neutropenia with impaired host defense against microbial infection in mice lacking androgen receptor. The Journal of Experimental Medicine. 206: 1181-99. PMID 19414555 DOI: 10.1084/jem.20082521  0.76
2009 Altuwaijri S, Chuang KH, Lai KP, Lai JJ, Lin HY, Young FM, Bottaro A, Tsai MY, Zeng WP, Chang HC, Yeh S, Chang C. Susceptibility to autoimmunity and B cell resistance to apoptosis in mice lacking androgen receptor in B cells. Molecular Endocrinology (Baltimore, Md.). 23: 444-53. PMID 19164450 DOI: 10.1210/me.2008-0106  0.76
2009 Yu SQ, Lai KP, Xia SJ, Chang HC, Chang C, Yeh S. The diverse and contrasting effects of using human prostate cancer cell lines to study androgen receptor roles in prostate cancer. Asian Journal of Andrology. 11: 39-48. PMID 19098932 DOI: 10.1038/aja.2008.44  0.76
2008 Niu Y, Altuwaijri S, Lai KP, Wu CT, Ricke WA, Messing EM, Yao J, Yeh S, Chang C. Androgen receptor is a tumor suppressor and proliferator in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 105: 12182-7. PMID 18723679 DOI: 10.1073/pnas.0804700105  0.4
2008 Niu Y, Altuwaijri S, Yeh S, Lai KP, Yu S, Chuang KH, Huang SP, Lardy H, Chang C. Targeting the stromal androgen receptor in primary prostate tumors at earlier stages Proceedings of the National Academy of Sciences of the United States of America. 105: 12188-12193. PMID 18723670 DOI: 10.1073/pnas.0804701105  0.4
2005 Su JL, Lai KP, Chen CA, Yang CY, Chen PS, Chang CC, Chou CH, Hu CL, Kuo ML, Hsieh CY, Wei LH. A novel peptide specifically binding to interleukin-6 receptor (gp80) inhibits angiogenesis and tumor growth. Cancer Research. 65: 4827-35. PMID 15930303 DOI: 10.1158/0008-5472.CAN-05-0188  0.76
2005 Wei LH, Lai KP, Chen CA, Cheng CH, Huang YJ, Chou CH, Kuo ML, Hsieh CY. Arsenic trioxide prevents radiation-enhanced tumor invasiveness and inhibits matrix metalloproteinase-9 through downregulation of nuclear factor kappaB. Oncogene. 24: 390-8. PMID 15531921 DOI: 10.1038/sj.onc.1208192  0.36
2005 Chou CH, Wei LH, Kuo ML, Huang YJ, Lai KP, Chen CA, Hsieh CY. Up-regulation of interleukin-6 in human ovarian cancer cell via a Gi/PI3K-Akt/NF-kappaB pathway by lysophosphatidic acid, an ovarian cancer-activating factor. Carcinogenesis. 26: 45-52. PMID 15471896 DOI: 10.1093/carcin/bgh301  0.36
2004 Hsieh CY, Chen CA, Chou CH, Lai KP, Jeng YM, Kuo ML, Wei LH. Overexpression of Her-2/NEU in epithelial ovarian carcinoma induces vascular endothelial growth factor C by activating NF-kappa B: implications for malignant ascites formation and tumor lymphangiogenesis. Journal of Biomedical Science. 11: 249-59. PMID 14966375 DOI: 10.1159/000076037  0.36
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