Jose D. Vela - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
Area:
pain, adrenergics

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Romero L, Merlos M, Vela JM. Antinociception by Sigma-1 Receptor Antagonists: Central and Peripheral Effects Advances in Pharmacology. DOI: 10.1016/bs.apha.2015.11.003  0.72
2015 Díaz JL, Christmann U, Fernández A, Torrens A, Port A, Pascual R, Álvarez I, Burgueño J, Monroy X, Montero A, Balada A, Vela JM, Almansa C. Synthesis and structure-activity relationship study of a new series of selective σ(1) receptor ligands for the treatment of pain: 4-aminotriazoles. Journal of Medicinal Chemistry. 58: 2441-51. PMID 25658964 DOI: 10.1021/jm501920g  0.72
2015 Rodríguez-Muñoz M, Sánchez-Blázquez P, Herrero-Labrador R, Martínez-Murillo R, Merlos M, Vela JM, Garzón J. The σ1 receptor engages the redox-regulated HINT1 protein to bring opioid analgesia under NMDA receptor negative control. Antioxidants & Redox Signaling. 22: 799-818. PMID 25557043 DOI: 10.1089/ars.2014.5993  0.72
2015 Mazo I, Roza C, Zamanillo D, Merlos M, Vela JM, Lopez-Garcia JA. Effects of centrally acting analgesics on spinal segmental reflexes and wind-up. European Journal of Pain (London, England). 19: 1012-20. PMID 25469831 DOI: 10.1002/Ejp.629  0.72
2015 Vela JM, Merlos M, Almansa C. Investigational sigma-1 receptor antagonists for the treatment of pain Expert Opinion On Investigational Drugs. 24: 883-896. DOI: 10.1517/13543784.2015.1048334  0.72
2014 Almansa C, Vela JM. Selective sigma-1 receptor antagonists for the treatment of pain. Future Medicinal Chemistry. 6: 1179-99. PMID 25078137 DOI: 10.4155/fmc.14.54  0.72
2014 Gris G, Merlos M, Vela JM, Zamanillo D, Portillo-Salido E. S1RA, a selective sigma-1 receptor antagonist, inhibits inflammatory pain in the carrageenan and complete Freund's adjuvant models in mice. Behavioural Pharmacology. 25: 226-35. PMID 24776490 DOI: 10.1097/FBP.0000000000000038  0.72
2014 Nieto FR, Cendán CM, Cañizares FJ, Cubero MA, Vela JM, Fernández-Segura E, Baeyens JM. Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensory-nerve mitochondrial abnormalities and neuropathic pain in mice. Molecular Pain. 10: 11. PMID 24517272 DOI: 10.1186/1744-8069-10-11  0.72
2014 Vidal-Torres A, Fernández-Pastor B, Carceller A, Vela JM, Merlos M, Zamanillo D. Effects of the selective sigma-1 receptor antagonist S1RA on formalin-induced pain behavior and neurotransmitter release in the spinal cord in rats. Journal of Neurochemistry. 129: 484-94. PMID 24384038 DOI: 10.1111/jnc.12648  0.72
2014 Gómez-Soler M, Fernández-Dueñas V, Portillo-Salido E, Pérez P, Zamanillo D, Vela JM, Burgueño J, Ciruela F. Predicting the antinociceptive efficacy of σ(1) receptor ligands by a novel receptor fluorescence resonance energy transfer (FRET) based biosensor. Journal of Medicinal Chemistry. 57: 238-42. PMID 24354313 DOI: 10.1021/Jm401529T  0.72
2014 Romero L, Vela JM. Alternative Models in Drug Discovery and Development Part II: In Vivo Nonmammalian and Exploratory/Experimental Human Models In Vivo Models For Drug Discovery. 59-90. DOI: 10.1002/9783527679348.ch03  0.72
2014 Romero L, Vela JM. Alternative Models in Drug Discovery and Development Part I: In Silico and In Vitro Models In Vivo Models For Drug Discovery. 27-58. DOI: 10.1002/9783527679348.ch02  0.72
2014 Vela JM, Maldonado R, Hamon M. The 3Ns of Preclinical Animal Models in Biomedical Research In Vivo Models For Drug Discovery. 1-26. DOI: 10.1002/9783527679348.ch01  0.72
2014 Vela JM, Maldonado R, Hamon M. In Vivo Models for Drug Discovery In Vivo Models For Drug Discovery. 1-561. DOI: 10.1002/9783527679348  0.72
2013 Vidal-Torres A, de la Puente B, Rocasalbas M, Touriño C, Bura SA, Fernández-Pastor B, Romero L, Codony X, Zamanillo D, Buschmann H, Merlos M, Baeyens JM, Maldonado R, Vela JM. Sigma-1 receptor antagonism as opioid adjuvant strategy: enhancement of opioid antinociception without increasing adverse effects. European Journal of Pharmacology. 711: 63-72. PMID 23632394 DOI: 10.1016/j.ejphar.2013.04.018  0.72
2013 Díaz JL, Christmann U, Fernández A, Luengo M, Bordas M, Enrech R, Carro M, Pascual R, Burgueño J, Merlos M, Benet-Buchholz J, Cerón-Bertran J, Ramírez J, Reinoso RF, Fernández de Henestrosa AR, ... Vela JM, et al. Synthesis and biological evaluation of a new series of hexahydro-2H-pyrano[3,2-c]quinolines as novel selective σ1 receptor ligands. Journal of Medicinal Chemistry. 56: 3656-65. PMID 23560650 DOI: 10.1021/jm400181k  0.72
2013 Zamanillo D, Romero L, Merlos M, Vela JM. Sigma 1 receptor: a new therapeutic target for pain. European Journal of Pharmacology. 716: 78-93. PMID 23500210 DOI: 10.1016/j.ejphar.2013.01.068  0.72
2013 Iñiguez MA, Punzón C, Nieto R, Burgueño J, Vela JM, Fresno M. Inhibitory effects of sigma-2 receptor agonists on T lymphocyte activation. Frontiers in Pharmacology. 4: 23. PMID 23494519 DOI: 10.3389/fphar.2013.00023  0.72
2013 Bura AS, Guegan T, Zamanillo D, Vela JM, Maldonado R. Operant self-administration of a sigma ligand improves nociceptive and emotional manifestations of neuropathic pain. European Journal of Pain (London, England). 17: 832-43. PMID 23172791 DOI: 10.1002/j.1532-2149.2012.00251.x  0.72
2012 Nieto FR, Cendán CM, Sánchez-Fernández C, Cobos EJ, Entrena JM, Tejada MA, Zamanillo D, Vela JM, Baeyens JM. Role of sigma-1 receptors in paclitaxel-induced neuropathic pain in mice. The Journal of Pain : Official Journal of the American Pain Society. 13: 1107-21. PMID 23063344 DOI: 10.1016/j.jpain.2012.08.006  0.72
2012 Vidal-Torres A, Carceller A, Zamanillo D, Merlos M, Vela JM, Fernández-Pastor B. Evaluation of formalin-induced pain behavior and glutamate release in the spinal dorsal horn using in vivo microdialysis in conscious rats. Journal of Pharmacological Sciences. 120: 129-32. PMID 22986364 DOI: DN/JST.JSTAGE/jphs/12105SC  0.72
2012 Viguier F, Michot B, Kayser V, Bernard JF, Vela JM, Hamon M, Bourgoin S. GABA, but not opioids, mediates the anti-hyperalgesic effects of 5-HT7 receptor activation in rats suffering from neuropathic pain. Neuropharmacology. 63: 1093-106. PMID 22820553 DOI: 10.1016/j.neuropharm.2012.07.023  0.72
2012 Díaz JL, Cuberes R, Berrocal J, Contijoch M, Christmann U, Fernández A, Port A, Holenz J, Buschmann H, Laggner C, Serafini MT, Burgueño J, Zamanillo D, Merlos M, Vela JM, et al. Synthesis and biological evaluation of the 1-arylpyrazole class of σ(1) receptor antagonists: identification of 4-{2-[5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl}morpholine (S1RA, E-52862). Journal of Medicinal Chemistry. 55: 8211-24. PMID 22784008 DOI: 10.1021/jm3007323  0.72
2012 Brenchat A, Rocasalbas M, Zamanillo D, Hamon M, Vela JM, Romero L. Assessment of 5-HT(7) Receptor Agonists Selectivity Using Nociceptive and Thermoregulation Tests in Knockout versus Wild-Type Mice. Advances in Pharmacological Sciences. 2012: 312041. PMID 22761612 DOI: 10.1155/2012/312041  0.72
2012 Brenchat A, Zamanillo D, Hamon M, Romero L, Vela JM. Role of peripheral versus spinal 5-HT(7) receptors in the modulation of pain undersensitizing conditions. European Journal of Pain (London, England). 16: 72-81. PMID 21843960 DOI: 10.1016/j.ejpain.2011.07.004  0.72
2010 Brenchat A, Nadal X, Romero L, Ovalle S, Muro A, Sánchez-Arroyos R, Portillo-Salido E, Pujol M, Montero A, Codony X, Burgueño J, Zamanillo D, Hamon M, Maldonado R, Vela JM. Pharmacological activation of 5-HT7 receptors reduces nerve injury-induced mechanical and thermal hypersensitivity. Pain. 149: 483-94. PMID 20399562 DOI: 10.1016/j.pain.2010.03.007  0.72
2010 Varin T, Gutiérrez-de-Terán H, Castro M, Brea J, Fabis F, Dauphin F, Aqvist J, Lepailleur A, Perez P, Burgueño J, Vela JM, Loza MI, Rodrigo J. Phe369(7.38) at human 5-HT(7) receptors confers interspecies selectivity to antagonists and partial agonists. British Journal of Pharmacology. 159: 1069-81. PMID 19922537 DOI: 10.1111/J.1476-5381.2009.00481.X  0.72
2010 Kayser V, Viguier F, Ioannidi M, Bernard JF, Latrémolière A, Michot B, Vela JM, Buschmann H, Hamon M, Bourgoin S. Differential anti-neuropathic pain effects of tetrodotoxin in sciatic nerve- versus infraorbital nerve-ligated rats--behavioral, pharmacological and immunohistochemical investigations. Neuropharmacology. 58: 474-87. PMID 19747496 DOI: 10.1016/j.neuropharm.2009.09.003  0.72
2009 Brenchat A, Romero L, García M, Pujol M, Burgueño J, Torrens A, Hamon M, Baeyens JM, Buschmann H, Zamanillo D, Vela JM. 5-HT7 receptor activation inhibits mechanical hypersensitivity secondary to capsaicin sensitization in mice. Pain. 141: 239-47. PMID 19118950 DOI: 10.1016/j.pain.2008.11.009  0.72
2008 Patwardhan AM, Vela J, Farugia J, Vela K, Hargreaves KM. Trigeminal nociceptors express prostaglandin receptors. Journal of Dental Research. 87: 262-6. PMID 18296611 DOI: 10.1177/154405910808700306  0.72
2006 Paz Gavilán M, Vela J, Castaño A, Ramos B, del Río JC, Vitorica J, Ruano D. Cellular environment facilitates protein accumulation in aged rat hippocampus. Neurobiology of Aging. 27: 973-82. PMID 15964666 DOI: 10.1016/j.neurobiolaging.2005.05.010  0.72
2004 Ramos B, Lopez-Tellez JF, Vela J, Baglietto-Vargas D, del Rio JC, Ruano D, Gutierrez A, Vitorica J. Expression of alpha 5 GABAA receptor subunit in developing rat hippocampus. Brain Research. Developmental Brain Research. 151: 87-98. PMID 15246695 DOI: 10.1016/j.devbrainres.2004.04.003  0.72
2004 Palacios G, Muro A, Verdú E, Pumarola M, Vela JM. Immunohistochemical localization of the sigma1 receptor in Schwann cells of rat sciatic nerve. Brain Research. 1007: 65-70. PMID 15064136 DOI: 10.1016/j.brainres.2004.02.013  0.72
2004 Lopez-Tellez JF, Vela J, del Rio JC, Ramos B, Baglietto-Vargas D, Santa-Maria C, Ruano D, Gutierrez A, Vitorica J. Postnatal development of the alpha1 containing GABAA receptor subunit in rat hippocampus. Brain Research. Developmental Brain Research. 148: 129-41. PMID 14757527 DOI: 10.1016/j.devbrainres.2003.11.010  0.72
2003 Verdú E, García-Alías G, Forés J, Vela JM, Cuadras J, López-Vales R, Navarro X. Morphological characterization of photochemical graded spinal cord injury in the rat. Journal of Neurotrauma. 20: 483-99. PMID 12803980 DOI: 10.1089/089771503765355559  0.72
2003 Vela J, Gutierrez A, Vitorica J, Ruano D. Rat hippocampal GABAergic molecular markers are differentially affected by ageing. Journal of Neurochemistry. 85: 368-77. PMID 12675913  0.72
2001 Vela J, Vitorica J, Ruano D. Rapid PCR-mediated synthesis of competitor molecules for accurate quantification of beta(2) GABA(A) receptor subunit mRNA. Brain Research. Brain Research Protocols. 8: 184-90. PMID 11733194 DOI: 10.1016/S1385-299X(01)00109-X  0.72
2000 Ruano D, Araujo F, Revilla E, Vela J, Bergis O, Vitorica J. GABAA and alpha-amino-3-hydroxy-5-methylsoxazole-4-propionate receptors are differentially affected by aging in the rat hippocampus. The Journal of Biological Chemistry. 275: 19585-93. PMID 10751391 DOI: 10.1074/jbc.M000700200  0.72
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