Year |
Citation |
Score |
2020 |
Khambati F, Padmanabhan J, Chellappan S. Abstract 1011: Tank binding kinase (TBK1) inhibitor BX795 impairs anti-tumor efficacy of T cells by abrogating granzyme and perforin mobilization Immunology. 80: 1011-1011. DOI: 10.1158/1538-7445.Am2020-1011 |
0.341 |
|
2018 |
Bhutada I, Chellappan S, Padmanabhan J. Abstract 2310: Targeting transcription-associated CDKs is an effective way to combat glioblastoma and medulloblastoma with minimal effect on primary neurons Cancer Research. 78: 2310-2310. DOI: 10.1158/1538-7445.Am2018-2310 |
0.363 |
|
2017 |
Kirouac L, Rajic AJ, Cribbs DH, Padmanabhan J. Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer's Disease. Eneuro. 4. PMID 28374012 DOI: 10.1523/ENEURO.0149-16.2017 |
0.465 |
|
2017 |
Buss S, Fried PJ, Padmanabhan J, Pascual-Leone A. ATROPHY IN DISTRIBUTED BRAIN NETWORKS CORRELATES WITH PERFORMANCE ON MEMORY TESTS IN AD PATIENTS Alzheimer's & Dementia. 13: P1555-P1556. DOI: 10.1016/J.Jalz.2017.07.697 |
0.313 |
|
2016 |
Srikumar T, Padmanabhan J. Potential Use of Flavopiridol in Treatment of Chronic Diseases. Advances in Experimental Medicine and Biology. 929: 209-228. PMID 27771926 DOI: 10.1007/978-3-319-41342-6_9 |
0.34 |
|
2016 |
Chaput D, Kirouac L, Stevens SM, Padmanabhan J. Potential role of PCTAIRE-2, PCTAIRE-3 and P-Histone H4 in amyloid precursor protein-dependent Alzheimer pathology. Oncotarget. 7: 8481-97. PMID 26885753 DOI: 10.18632/Oncotarget.7380 |
0.522 |
|
2015 |
Woods N, Trevino J, Coppola D, Chellappan S, Yang S, Padmanabhan J. Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and β-catenin signaling. Oncotarget. PMID 26440150 DOI: 10.18632/Oncotarget.5933 |
0.305 |
|
2015 |
Padmanabhan J. Immunostaining analysis of tissue cultured cells and tissue sections using phospho-Histone H3 (Serine 10) antibody. Methods in Molecular Biology (Clifton, N.J.). 1288: 231-44. PMID 25827883 DOI: 10.1007/978-1-4939-2474-5_13 |
0.311 |
|
2015 |
Padmanabhan J, Brown KR, Padilla A, Shelanski ML. Functional role of RNA polymerase II and P70 S6 kinase in KCl withdrawal-induced cerebellar granule neuron apoptosis. The Journal of Biological Chemistry. 290: 5267-79. PMID 25568312 DOI: 10.1074/Jbc.M114.575225 |
0.382 |
|
2014 |
Ari C, Borysov SI, Wu J, Padmanabhan J, Potter H. Alzheimer amyloid beta inhibition of Eg5/kinesin 5 reduces neurotrophin and/or transmitter receptor function. Neurobiology of Aging. 35: 1839-49. PMID 24636920 DOI: 10.1016/J.Neurobiolaging.2014.02.006 |
0.531 |
|
2014 |
Wang A, Potter H, Bennett S, Caneus J, Ari C, Borysov S, Padmanabhan J, Wu J, Granic A. P2-011: Aβ INHIBITION OF KINESIN 5 DISRUPTS THE LOCALIZATION AND FUNCTION OF MEMBRANE PROTEINS: IMPLICATIONS FOR NEURONAL RESPONSES TO NEUROTROPHINS, NEUROTRANSMITTERS, GLUCOSE, AND LIPIDS IN AD Alzheimer's & Dementia. 10: P474-P474. DOI: 10.1016/J.Jalz.2014.05.684 |
0.445 |
|
2013 |
Tyagi E, Fiorelli T, Norden M, Padmanabhan J. Alpha 1-Antichymotrypsin, an Inflammatory Protein Overexpressed in the Brains of Patients with Alzheimer's Disease, Induces Tau Hyperphosphorylation through c-Jun N-Terminal Kinase Activation. International Journal of Alzheimer's Disease. 2013: 606083. PMID 24175110 DOI: 10.1155/2013/606083 |
0.742 |
|
2013 |
Woods NK, Padmanabhan J. Inhibition of amyloid precursor protein processing enhances gemcitabine-mediated cytotoxicity in pancreatic cancer cells. The Journal of Biological Chemistry. 288: 30114-24. PMID 24022491 DOI: 10.1074/Jbc.M113.459255 |
0.36 |
|
2013 |
Fiorelli T, Kirouac L, Padmanabhan J. Altered processing of amyloid precursor protein in cells undergoing apoptosis. Plos One. 8: e57979. PMID 23469123 DOI: 10.1371/Journal.Pone.0057979 |
0.729 |
|
2013 |
Woods N, Padmanabhan J. Abstract 4010: Role of ADAM10-mediated APP processing in pancreatic cancer. Cancer Research. 73: 4010-4010. DOI: 10.1158/1538-7445.Am2013-4010 |
0.39 |
|
2012 |
Chaput D, Kirouac LH, Bell-Temin H, Stevens SM, Padmanabhan J. SILAC-based proteomic analysis to investigate the impact of amyloid precursor protein expression in neuronal-like B103 cells. Electrophoresis. 33: 3728-37. PMID 23161580 DOI: 10.1002/Elps.201200251 |
0.533 |
|
2012 |
Woods NK, Padmanabhan J. Neuronal calcium signaling and Alzheimer's disease. Advances in Experimental Medicine and Biology. 740: 1193-217. PMID 22453989 DOI: 10.1007/978-94-007-2888-2_54 |
0.382 |
|
2012 |
Ari C, Borysov S, Wu J, Padmanabhan J, Boyd T, Granic A, Potter H. P3-036: Aß inhibition of kinesin 5 induces neurotransmitter and neurotrophin receptor mislocalization and dysfunction Alzheimer's & Dementia. 8: P468-P468. DOI: 10.1016/J.Jalz.2012.05.1254 |
0.367 |
|
2011 |
Judge M, Hornbeck L, Potter H, Padmanabhan J. Mitosis-specific phosphorylation of amyloid precursor protein at threonine 668 leads to its altered processing and association with centrosomes. Molecular Neurodegeneration. 6: 80. PMID 22112898 DOI: 10.1186/1750-1326-6-80 |
0.556 |
|
2011 |
Borysov SI, Granic A, Padmanabhan J, Walczak CE, Potter H. Alzheimer Aβ disrupts the mitotic spindle and directly inhibits mitotic microtubule motors. Cell Cycle (Georgetown, Tex.). 10: 1397-410. PMID 21566458 DOI: 10.4161/Cc.10.9.15478 |
0.473 |
|
2011 |
Potter H, Borysov S, Ari C, Granic A, Wu J, Padmanabhan J, Walczak C. P4-324: Aβ inhibits specific kinesin motors involved in both mitosis and neuronal function; potential implications for neurogenesis and neuroplasticity in Alzheimer's disease and Down syndrome Alzheimer's & Dementia. 7: e24-e24. DOI: 10.1016/J.Jalz.2011.09.069 |
0.42 |
|
2010 |
Boyd TD, Bennett SP, Mori T, Governatori N, Runfeldt M, Norden M, Padmanabhan J, Neame P, Wefes I, Sanchez-Ramos J, Arendash GW, Potter H. GM-CSF upregulated in rheumatoid arthritis reverses cognitive impairment and amyloidosis in Alzheimer mice. Journal of Alzheimer's Disease : Jad. 21: 507-18. PMID 20555144 DOI: 10.3233/Jad-2010-091471 |
0.41 |
|
2010 |
Abisambra JF, Fiorelli T, Padmanabhan J, Neame P, Wefes I, Potter H. LDLR expression and localization are altered in mouse and human cell culture models of Alzheimer's disease. Plos One. 5: e8556. PMID 20049331 DOI: 10.1371/Journal.Pone.0008556 |
0.733 |
|
2010 |
Granic A, Padmanabhan J, Norden M, Potter H. Alzheimer Abeta peptide induces chromosome mis-segregation and aneuploidy, including trisomy 21: requirement for tau and APP. Molecular Biology of the Cell. 21: 511-20. PMID 20032300 DOI: 10.1091/Mbc.E09-10-0850 |
0.559 |
|
2010 |
Potter H, Granic A, Borysov S, Abisambra JF, Padmanabhan J, Wefes I, Goodwin B, Neame P, Fiorelli T, Norden M. P4-005: Alzheimer Aβ Induces Chromosome Mis-segregation, Microtubule Defects, Receptor Mis-localization, and Inhibition of Mitotic/Neuronal Kinesins: Implications for Neurogenesis and Plasticity in Neurodegenrative Diseases Alzheimer's & Dementia. 6: e22-e22. DOI: 10.1016/J.Jalz.2010.08.066 |
0.726 |
|
2010 |
Padmanabhan J, Fiorelli T, Hornbeck L. Microtubule destabilization leads to APP phosphorylation and processing: Implications for Alzheimer's disease pathogenesis Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.920 |
0.743 |
|
2009 |
Bennett SP, Boyd TD, Norden M, Padmanabhan J, Neame P, Wefes I, Potter H. A novel technique for simultaneous bilateral brain infusions in a mouse model of neurodegenerative disease. Journal of Neuroscience Methods. 184: 320-6. PMID 19732796 DOI: 10.1016/J.Jneumeth.2009.08.021 |
0.512 |
|
2009 |
Padmanabhan J. Detection of histone H3 phosphorylation in cultured cells and tissue sections by immunostaining. Methods in Molecular Biology (Clifton, N.J.). 523: 311-22. PMID 19381929 DOI: 10.1007/978-1-59745-190-1_21 |
0.323 |
|
2008 |
Boeras DI, Granic A, Padmanabhan J, Crespo NC, Rojiani AM, Potter H. Alzheimer's presenilin 1 causes chromosome missegregation and aneuploidy. Neurobiology of Aging. 29: 319-28. PMID 17169464 DOI: 10.1016/J.Neurobiolaging.2006.10.027 |
0.451 |
|
2008 |
Padmanabhan J, Bennett S, Levy M, Potter H. O2-05-01: In vivo
induction of Tau hyperphosphorylation by the inflammatory protein alpha 1-antichymotrypsin Alzheimer's & Dementia. 4: T140-T141. DOI: 10.1016/J.Jalz.2008.05.340 |
0.332 |
|
2008 |
Goodwin B, Padmanabhan J, Granic A, Owens C, Crespo N, Potter H. P3-315: Inhibition of gamma-secretase activity induces cell cycle defects and chromosome missegregation Alzheimer's & Dementia. 4: T614-T614. DOI: 10.1016/J.Jalz.2008.05.1884 |
0.343 |
|
2008 |
Potter H, Granic A, Boeras D, Crespo N, Padmanabhan J. P1-432: Alzheimer's mutant presenilin-1 and amyloid precursor protein genes cause chromosome missegregation and aneuploidy through the action of Abeta peptide Alzheimer's & Dementia. 4: T346-T346. DOI: 10.1016/J.Jalz.2008.05.1014 |
0.446 |
|
2007 |
Padmanabhan J, Brown K, Shelanski ML. Cell cycle inhibition and retinoblastoma protein overexpression prevent Purkinje cell death in organotypic slice cultures. Developmental Neurobiology. 67: 818-26. PMID 17443827 DOI: 10.1002/Dneu.20394 |
0.385 |
|
2006 |
Dasgupta P, Padmanabhan J, Chellappan S. Rb function in the apoptosis and senescence of non-neuronal and neuronal cells: role in oncogenesis. Current Molecular Medicine. 6: 719-29. PMID 17100598 DOI: 10.2174/1566524010606070719 |
0.375 |
|
2006 |
Padmanabhan J, Levy M, Dickson DW, Potter H. Alpha1-antichymotrypsin, an inflammatory protein overexpressed in Alzheimer's disease brain, induces tau phosphorylation in neurons. Brain : a Journal of Neurology. 129: 3020-34. PMID 16987932 DOI: 10.1093/Brain/Awl255 |
0.599 |
|
2006 |
Potter H, Boeras DI, Granic A, Padmanabhan J, Crespo NC, Crespo NC, Rojiani AM. P3-227: Chromosome aneuploidy, including human trisomy 21 caused by Alzheimer's mutant presenilin 1/ Î3
-secretase Alzheimer's & Dementia. 2: S442-S442. DOI: 10.1016/J.Jalz.2006.05.1496 |
0.397 |
|
2004 |
Dasgupta P, Sun J, Wang S, Fusaro G, Betts V, Padmanabhan J, Sebti SM, Chellappan SP. Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis. Molecular and Cellular Biology. 24: 9527-41. PMID 15485920 DOI: 10.1128/Mcb.24.21.9527-9541.2004 |
0.334 |
|
2004 |
Boeras DI, Granic A, Padmanabhan J, Potter H. P4-293 The presenilins, chromosome missegregation, and Alzheimer's disease Neurobiology of Aging. 25: S558. DOI: 10.1016/S0197-4580(04)81851-7 |
0.416 |
|
2004 |
Padmanabhan J, Potter H. P3-217 Aberrant mitosis specific protein phosphorylation in Alzheimer's disease Neurobiology of Aging. 25: S417. DOI: 10.1016/S0197-4580(04)81367-8 |
0.466 |
|
2002 |
Wang S, Fusaro G, Padmanabhan J, Chellappan SP. Prohibitin co-localizes with Rb in the nucleus and recruits N-CoR and HDAC1 for transcriptional repression. Oncogene. 21: 8388-96. PMID 12466959 DOI: 10.1038/Sj.Onc.1205944 |
0.315 |
|
2000 |
Park DS, Morris EJ, Bremner R, Keramaris E, Padmanabhan J, Rosenbaum M, Shelanski ML, Geller HM, Greene LA. Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3104-14. PMID 10777774 DOI: 10.1523/Jneurosci.20-09-03104.2000 |
0.393 |
|
1999 |
Padmanabhan J, Park DS, Greene LA, Shelanski ML. Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8747-56. PMID 10516294 DOI: 10.1523/Jneurosci.19-20-08747.1999 |
0.401 |
|
1999 |
Padmanabhan J, Clayton D, Shelanski ML. Dibutyryl cyclic AMP-induced process formation in astrocytes is associated with a decrease in tyrosine phosphorylation of focal adhesion kinase and paxillin. Journal of Neurobiology. 39: 407-22. PMID 10363913 DOI: 10.1002/(Sici)1097-4695(19990605)39:3<407::Aid-Neu7>3.0.Co;2-S |
0.361 |
|
1998 |
Park DS, Morris EJ, Padmanabhan J, Shelanski ML, Geller HM, Greene LA. Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents. The Journal of Cell Biology. 143: 457-67. PMID 9786955 DOI: 10.1083/Jcb.143.2.457 |
0.365 |
|
1998 |
Padmanabhan J, Shelanski ML. Process formation in astrocytes: modulation of cytoskeletal proteins. Neurochemical Research. 23: 377-84. PMID 9482250 DOI: 10.1023/A:1022413718447 |
0.319 |
|
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