Year |
Citation |
Score |
2024 |
Sordo L, Ubele MF, Boaz KA, Mefford JL, Jones ED, McCarty KL, van Rooyen HY, Smiley J, Bembenek Bailey SA, Perpich JA, Meacham B, Powell DK, Bresch F, Crump JW, Phelan MJ, ... ... Norris CM, et al. Calcineurin/NFAT inhibitors maintain cognition in a preclinical prevention study in an aging canine model of Alzheimer disease. Neurobiology of Aging. 146: 1-14. PMID 39547056 DOI: 10.1016/j.neurobiolaging.2024.11.003 |
0.344 |
|
2024 |
Weiss BE, Kraner SD, Artiushin IA, Norris CM. Elevated calcineurin activity in primary astrocytes leads to the dephosphorylation of connexin 43 in conjunction with increased membrane permeability. Neuroreport. 35: 673-678. PMID 38813906 DOI: 10.1097/WNR.0000000000002051 |
0.331 |
|
2024 |
Noche JA, Radhakrishnan H, Ubele MF, Boaz K, Mefford JL, Jones ED, Perpich JA, McCarty K, Meacham B, Smiley J, Bailey SAB, Puskás LG, Powell DK, Sordo L, Phelan MJ, ... Norris CM, et al. Age-related brain atrophy and the positive effects of behavioral enrichment in middle-aged beagles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 38561226 DOI: 10.1523/JNEUROSCI.2366-23.2024 |
0.314 |
|
2023 |
Kraner SD, Sompol P, Prateeptrang S, Promkan M, Hongthong S, Thongsopha N, Nelson PT, Norris CM. Development of a monoclonal antibody specific for a calpain-generated ∆48 kDa calcineurin fragment, a marker of distressed astrocytes. Journal of Neuroscience Methods. 402: 110012. PMID 37984591 DOI: 10.1016/j.jneumeth.2023.110012 |
0.379 |
|
2023 |
Norris CM. Is It Time to Repurpose Calcineurin Inhibitors for the Treatment of Cognitive Impairment and Dementia? Journal of Alzheimer's Disease : Jad. 95: 599-602. PMID 37661889 DOI: 10.3233/JAD-230780 |
0.31 |
|
2023 |
Sompol P, Gollihue JL, Weiss BE, Lin RL, Case SL, Kraner SD, Weekman EM, Gant JC, Rogers CB, Niedowicz DM, Sudduth TL, Powell DK, Lin AL, Nelson PT, Thibault O, ... ... Norris CM, et al. Targeting astrocyte signaling alleviates cerebrovascular and synaptic function deficits in a diet-based mouse model of small cerebral vessel disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36746627 DOI: 10.1523/JNEUROSCI.1333-22.2023 |
0.365 |
|
2021 |
Sompol P, Gollihue JL, Kraner SD, Artiushin IA, Cloyd RA, Chishti EA, Koren SA, Nation GK, Abisambra JF, Huzian O, Nagy LI, Santha M, Hackler L, Puskas LG, Norris CM. Q134R: Small chemical compound with NFAT inhibitory properties improves behavioral performance and synapse function in mouse models of amyloid pathology. Aging Cell. e13416. PMID 34117818 DOI: 10.1111/acel.13416 |
0.391 |
|
2021 |
Radhakrishnan H, Ubele M, Krumholz SM, Boaz K, Mefford JL, Jones ED, Meacham B, Smiley J, Puskás LG, Powell DK, Norris CM, Stark CEL, Head E. Tacrolimus protects against age-associated microstructural changes in the beagle brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33952632 DOI: 10.1523/JNEUROSCI.0361-21.2021 |
0.351 |
|
2021 |
Price BR, Johnson LA, Norris CM. Reactive Astrocytes: The nexus of pathological and clinical hallmarks of Alzheimer's disease. Ageing Research Reviews. 101335. PMID 33812051 DOI: 10.1016/j.arr.2021.101335 |
0.387 |
|
2020 |
Frazier HN, Anderson KL, Ghoweri AO, Lin RL, Hawkinson TR, Popa GJ, Sompol P, Mendenhall MD, Norris CM, Thibault O. Molecular elevation of insulin receptor signaling improves memory recall in aged Fischer 344 rats. Aging Cell. e13220. PMID 32852134 DOI: 10.1111/Acel.13220 |
0.303 |
|
2020 |
Dufort-Gervais J, Provost C, Charbonneau L, Norris CM, Calon F, Mongrain V, Brouillette J. Neuroligin-1 is altered in the hippocampus of Alzheimer's disease patients and mouse models, and modulates the toxicity of amyloid-beta oligomers. Scientific Reports. 10: 6956. PMID 32332783 DOI: 10.1038/S41598-020-63255-6 |
0.497 |
|
2020 |
Gollihue JL, Norris CM. Astrocyte mitochondria: Central players and potential therapeutic targets for neurodegenerative diseases and injury. Ageing Research Reviews. 59: 101039. PMID 32105849 DOI: 10.1016/J.Arr.2020.101039 |
0.411 |
|
2019 |
Quadri Z, Johnson N, Zamudio F, Miller A, Peters M, Smeltzer S, Hunt JB, Housley SB, Brown B, Kramer S, Norris CM, Nash K, Weeber E, Lee DC, Selenica MB. Overexpression of human wtTDP-43 causes impairment in hippocampal plasticity and behavioral deficits in CAMKII-tTa transgenic mouse model. Molecular and Cellular Neurosciences. 103418. PMID 31705957 DOI: 10.1016/J.Mcn.2019.103418 |
0.332 |
|
2019 |
Hudson R, Renard J, Norris C, Rushlow WJ, Laviolette SR. Cannabidiol Counteracts the Psychotropic Side-Effects of Δ-9-Tetrahydrocannabinol in the Ventral Hippocampus Through Bi-Directional Control of ERK1-2 Phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31570536 DOI: 10.1523/Jneurosci.0708-19.2019 |
0.322 |
|
2019 |
Sompol P, Kraner SD, Gollihue JL, Thibault O, Wilcock DM, Norris CM. Astrocyte Activation And Hippocampal Synaptic Impairments In Mouse Models Of Amyloid Pathology And Cerebrovascular Dysfunction Alzheimers & Dementia. 15: 188. DOI: 10.1016/J.Jalz.2019.06.4394 |
0.445 |
|
2018 |
Kraner SD, Norris CM. Astrocyte Activation and the Calcineurin/NFAT Pathway in Cerebrovascular Disease. Frontiers in Aging Neuroscience. 10: 287. PMID 30297999 DOI: 10.3389/Fnagi.2018.00287 |
0.502 |
|
2018 |
Norris CM. Calcineurin: directing the damage in Alzheimer disease: An Editorial for 'Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain' on doi: 10.1111/jnc.14469. Journal of Neurochemistry. PMID 30256415 DOI: 10.1111/Jnc.14475 |
0.535 |
|
2018 |
Sompol P, Norris CM. Ca, Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases. Frontiers in Aging Neuroscience. 10: 199. PMID 30038565 DOI: 10.3389/Fnagi.2018.00199 |
0.533 |
|
2018 |
Castonguay D, Dufort-Gervais J, Ménard C, Chatterjee M, Quirion R, Bontempi B, Schneider JS, Arnsten AFT, Nairn AC, Norris CM, Ferland G, Bézard E, Gaudreau P, Lombroso PJ, Brouillette J. The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline. Current Biology : Cb. PMID 29576474 DOI: 10.1016/J.Cub.2018.02.047 |
0.364 |
|
2018 |
Frazier HN, Anderson KL, Maimaiti S, Ghoweri AO, Kraner SD, Popa GJ, Hampton KK, Mendenhall MD, Norris CM, Craven RJ, Thibault O. Expression of a Constitutively Active Human Insulin Receptor in Hippocampal Neurons Does Not Alter VGCC Currents. Neurochemical Research. PMID 29572644 DOI: 10.1007/S11064-018-2510-2 |
0.328 |
|
2018 |
Norris CM, Sompol P, Gollihue JL, Cloyd R, Koren S, Nation GK, Abisambra JF, Kraner SD, Artiushin IA, Huzian O, Puskas LG. P4-218: Q134R: Novel Small Chemical Compound With Nfat Inhibitory Properties Ameliorates Synaptic Deficits In A Mouse Model Of Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.07.039 |
0.383 |
|
2017 |
Price BR, Norris CM, Sompol P, Wilcock DM. An emerging role of astrocytes in vascular contributions to cognitive impairment and dementia (VCID). Journal of Neurochemistry. PMID 29222909 DOI: 10.1111/Jnc.14273 |
0.444 |
|
2017 |
Sompol P, Furman JL, Pleiss MM, Kraner SD, Artiushin IA, Batten SR, Quintero JE, Simmerman LA, Beckett TL, Lovell MA, Murphy MP, Gerhardt GA, Norris CM. Calcineurin/NFAT signaling in activated astrocytes drives network hyperexcitability in Aβ-bearing mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28559377 DOI: 10.1523/Jneurosci.0877-17.2017 |
0.508 |
|
2017 |
Manocha GD, Ghatak A, Puig KL, Kraner SD, Norris CM, Combs CK. NFATc2 Modulates Microglial Activation in the AβPP/PS1 Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 28505967 DOI: 10.3233/Jad-151203 |
0.489 |
|
2017 |
MacPherson KP, Sompol P, Kannarkat GT, Chang J, Sniffen L, Wildner ME, Norris CM, Tansey MG. Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice. Neurobiology of Disease. PMID 28237313 DOI: 10.1016/J.Nbd.2017.02.010 |
0.414 |
|
2016 |
Sudduth TL, Weekman EM, Price BR, Gooch JL, Woolums A, Norris CM, Wilcock DM. Time-course of glial changes in the hyperhomocysteinemia model of vascular cognitive impairment and dementia (VCID). Neuroscience. PMID 27890830 DOI: 10.1016/J.Neuroscience.2016.11.024 |
0.43 |
|
2016 |
Pleiss MM, Sompol P, Kraner SD, Abdul HM, Furman JL, Guttmann RP, Wilcock DM, Nelson PT, Norris CM. Calcineurin proteolysis in astrocytes: Implications for impaired synaptic function. Biochimica Et Biophysica Acta. PMID 27212416 DOI: 10.1016/J.Bbadis.2016.05.007 |
0.477 |
|
2016 |
Lovell MA, Lynn BC, Fister S, Bradley-Whitman M, Murphy MP, Beckett TL, Norris CM. A Novel Small Molecule Modulator of Amyloid Pathology. Journal of Alzheimer's Disease : Jad. PMID 27163808 DOI: 10.3233/Jad-151160 |
0.452 |
|
2016 |
Pettigrew LC, Kryscio RJ, Norris CM. The TNFα-Transgenic Rat: Hippocampal Synaptic Integrity, Cognition, Function, and Post-Ischemic Cell Loss. Plos One. 11: e0154721. PMID 27144978 DOI: 10.1371/Journal.Pone.0154721 |
0.429 |
|
2016 |
Furman JL, Sompol P, Kraner SD, Pleiss MM, Putman EJ, Dunkerson J, Mohmmad Abdul H, Roberts KN, Scheff SW, Norris CM. Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1502-15. PMID 26843634 DOI: 10.1523/Jneurosci.1930-15.2016 |
0.427 |
|
2016 |
Wilcock DM, Sudduth TL, Weekman EM, Pleiss MM, Woolums A, Norris CM. Neurovascular Astrocyte Dysfunction As A Key Mediator Of Vascular Cognitive Impairment Alzheimers & Dementia. 12: 270. DOI: 10.1016/J.Jalz.2016.06.489 |
0.322 |
|
2015 |
Norris CM, Sompol P, Roberts KN, Ansari M, Scheff SW. Pycnogenol protects CA3-CA1 synaptic function in a rat model of traumatic brain injury. Experimental Neurology. PMID 26607913 DOI: 10.1016/J.Expneurol.2015.11.006 |
0.38 |
|
2015 |
Norris CM, Sompol P, MacPherson KP, Tansey MG. P4-205: Peripheral administration of the novel tnf inhibitor xpro1595 improves synaptic function in the 5XFAD model of Alzheimer's disease Alzheimer's & Dementia. 11: P859-P859. DOI: 10.1016/J.Jalz.2015.08.033 |
0.42 |
|
2014 |
Furman JL, Norris CM. Calcineurin and glial signaling: neuroinflammation and beyond. Journal of Neuroinflammation. 11: 158. PMID 25199950 DOI: 10.1186/S12974-014-0158-7 |
0.441 |
|
2014 |
Niedowicz DM, Reeves VL, Platt TL, Kohler K, Beckett TL, Powell DK, Lee TL, Sexton TR, Song ES, Brewer LD, Latimer CS, Kraner SD, Larson KL, Ozcan S, Norris CM, et al. Obesity and diabetes cause cognitive dysfunction in the absence of accelerated β-amyloid deposition in a novel murine model of mixed or vascular dementia. Acta Neuropathologica Communications. 2: 64. PMID 24916066 DOI: 10.1186/2051-5960-2-64 |
0.335 |
|
2014 |
Gant JC, Blalock EM, Chen KC, Kadish I, Porter NM, Norris CM, Thibault O, Landfield PW. FK506-binding protein 1b/12.6: a key to aging-related hippocampal Ca2+ dysregulation? European Journal of Pharmacology. 739: 74-82. PMID 24291098 DOI: 10.1016/J.Ejphar.2013.10.070 |
0.442 |
|
2014 |
Pleiss MM, Furman JL, Abdul HM, Norris CM. A Novel Reagent Modulates Cn/Cx43 Interactions During The Progression Of Alzheimer'S Disease Alzheimers & Dementia. 10: 652. DOI: 10.1016/J.Jalz.2014.05.1157 |
0.318 |
|
2013 |
Sama DM, Norris CM. Calcium dysregulation and neuroinflammation: discrete and integrated mechanisms for age-related synaptic dysfunction. Ageing Research Reviews. 12: 982-95. PMID 23751484 DOI: 10.1016/J.Arr.2013.05.008 |
0.742 |
|
2012 |
Furman JL, Sama DM, Gant JC, Beckett TL, Murphy MP, Bachstetter AD, Van Eldik LJ, Norris CM. Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16129-40. PMID 23152597 DOI: 10.1523/Jneurosci.2323-12.2012 |
0.755 |
|
2012 |
Bachstetter AD, Norris CM, Sompol P, Wilcock DM, Goulding D, Neltner JH, St Clair D, Watterson DM, Van Eldik LJ. Early stage drug treatment that normalizes proinflammatory cytokine production attenuates synaptic dysfunction in a mouse model that exhibits age-dependent progression of Alzheimer's disease-related pathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10201-10. PMID 22836255 DOI: 10.1523/Jneurosci.1496-12.2012 |
0.449 |
|
2012 |
Sama DM, Mohmmad Abdul H, Furman JL, Artiushin IA, Szymkowski DE, Scheff SW, Norris CM. Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats. Plos One. 7: e38170. PMID 22666474 DOI: 10.1371/Journal.Pone.0038170 |
0.741 |
|
2012 |
Thibault O, Pancani T, Landfield PW, Norris CM. Reduction in neuronal L-type calcium channel activity in a double knock-in mouse model of Alzheimer's disease. Biochimica Et Biophysica Acta. 1822: 546-9. PMID 22265986 DOI: 10.1016/J.Bbadis.2012.01.004 |
0.436 |
|
2012 |
Furman J, Abdul HM, Norris C. Alterations in connexin 43 phosphorylation during the progression of Alzheimer's disease: Possible role of astrocytic calcineurin Alzheimers & Dementia. 8: 300. DOI: 10.1016/J.Jalz.2012.05.814 |
0.442 |
|
2011 |
Mathis DM, Furman JL, Norris CM. Preparation of acute hippocampal slices from rats and transgenic mice for the study of synaptic alterations during aging and amyloid pathology. Journal of Visualized Experiments : Jove. PMID 21490565 DOI: 10.3791/2330 |
0.411 |
|
2011 |
Gant JC, Chen KC, Norris CM, Kadish I, Thibault O, Blalock EM, Porter NM, Landfield PW. Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1693-703. PMID 21289178 DOI: 10.1523/Jneurosci.4805-10.2011 |
0.458 |
|
2011 |
Mohmmad Abdul H, Baig I, Levine H, Guttmann RP, Norris CM. Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture. Aging Cell. 10: 103-13. PMID 20969723 DOI: 10.1111/J.1474-9726.2010.00645.X |
0.492 |
|
2010 |
Abdul HM, Furman JL, Sama MA, Mathis DM, Norris CM. NFATs and Alzheimer's Disease. Molecular and Cellular Pharmacology. 2: 7-14. PMID 20401186 DOI: 10.4255/mcpharmacol.10.02 |
0.786 |
|
2010 |
Furman JL, Artiushin IA, Norris CM. Disparate effects of serum on basal and evoked NFAT activity in primary astrocyte cultures. Neuroscience Letters. 469: 365-9. PMID 20026181 DOI: 10.1016/J.Neulet.2009.12.029 |
0.401 |
|
2010 |
Norris CM, Blalock EM, Chen KC, Porter NM, Thibault O, Kraner SD, Landfield PW. Hippocampal 'zipper' slice studies reveal a necessary role for calcineurin in the increased activity of L-type Ca(2+) channels with aging. Neurobiology of Aging. 31: 328-38. PMID 18471936 DOI: 10.1016/J.Neurobiolaging.2008.03.026 |
0.451 |
|
2010 |
Norris CM, Abdul HM, Furman JL, Sama MA, Mathis DM. O4-04-05: Calcineurin: A dual threat in aging and Alzheimer's disease Alzheimer's & Dementia. 6: S156-S156. DOI: 10.1016/J.Jalz.2010.05.485 |
0.74 |
|
2009 |
Abdul HM, Sama MA, Furman JL, Mathis DM, Beckett TL, Weidner AM, Patel ES, Baig I, Murphy MP, LeVine H, Kraner SD, Norris CM. Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12957-69. PMID 19828810 DOI: 10.1523/Jneurosci.1064-09.2009 |
0.774 |
|
2009 |
Norris CM, Scheff SW. Recovery of afferent function and synaptic strength in hippocampal CA1 following traumatic brain injury. Journal of Neurotrauma. 26: 2269-78. PMID 19604098 DOI: 10.1089/Neu.2009.1029 |
0.362 |
|
2008 |
Sama MA, Mathis DM, Furman JL, Abdul HM, Artiushin IA, Kraner SD, Norris CM. Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity. The Journal of Biological Chemistry. 283: 21953-64. PMID 18541537 DOI: 10.1074/Jbc.M800148200 |
0.748 |
|
2008 |
Norris CM, Abdul HM, Kraner SD, Sama MA. P3-367: Alterations in the subcellular localization of calcineurin/NFAT isoforms in Alzheimer's disease: Implications for neuroinflammation Alzheimer's & Dementia. 4: T629-T629. DOI: 10.1016/J.Jalz.2008.05.1937 |
0.74 |
|
2007 |
Jeftinija DM, Wang QB, Hebert SL, Norris CM, Yan Z, Rich MM, Kraner SD. The Ca(V) 1.2 Ca(2+) channel is expressed in sarcolemma of type I and IIa myofibers of adult skeletal muscle. Muscle & Nerve. 36: 482-90. PMID 17636479 DOI: 10.1002/Mus.20842 |
0.325 |
|
2006 |
Norris CM, Blalock EM, Thibault O, Brewer LD, Clodfelter GV, Porter NM, Landfield PW. Electrophysiological mechanisms of delayed excitotoxicity: positive feedback loop between NMDA receptor current and depolarization-mediated glutamate release. Journal of Neurophysiology. 96: 2488-500. PMID 16914613 DOI: 10.1152/Jn.00593.2005 |
0.37 |
|
2005 |
Blalock EM, Chen KC, Stromberg AJ, Norris CM, Kadish I, Kraner SD, Porter NM, Landfield PW. Harnessing the power of gene microarrays for the study of brain aging and Alzheimer's disease: statistical reliability and functional correlation. Ageing Research Reviews. 4: 481-512. PMID 16257272 DOI: 10.1016/J.Arr.2005.06.006 |
0.402 |
|
2005 |
Norris CM, Kadish I, Blalock EM, Chen KC, Thibault V, Porter NM, Landfield PW, Kraner SD. Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4649-58. PMID 15872113 DOI: 10.1523/Jneurosci.0365-05.2005 |
0.553 |
|
2002 |
Norris CM, Blalock EM, Chen KC, Porter NM, Landfield PW. Calcineurin enhances L-type Ca(2+) channel activity in hippocampal neurons: increased effect with age in culture. Neuroscience. 110: 213-25. PMID 11958864 DOI: 10.1016/S0306-4522(01)00574-7 |
0.38 |
|
2001 |
Foster TC, Sharrow KM, Masse JR, Norris CM, Kumar A. Calcineurin Links Ca2+ Dysregulation with Brain Aging The Journal of Neuroscience. 21: 4066-4073. DOI: 10.1523/Jneurosci.21-11-04066.2001 |
0.448 |
|
1998 |
Norris CM, Halpain S, Foster TC. Alterations in the balance of protein kinase/phosphatase activities parallel reduced synaptic strength during aging. Journal of Neurophysiology. 80: 1567-70. PMID 9744962 DOI: 10.1152/Jn.1998.80.3.1567 |
0.392 |
|
1998 |
Foster TC, Norris CM. On slices, synaptosomes and dissociated neurones to study in vitro ageing physiology. Trends in Neurosciences. 21: 286-7. PMID 9683319 DOI: 10.1016/S0166-2236(98)01259-4 |
0.347 |
|
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