Rochelle Buffenstein - Publications

Affiliations: 
Physiology The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States 
Area:
Physiology Biology, Neuroscience Biology

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Yen K, Mehta HH, Kim SJ, Lue Y, Hoang J, Guerrero N, Port J, Bi Q, Navarrete G, Brandhorst S, Lewis KN, Wan J, Swerdloff R, Mattison JA, Buffenstein R, et al. The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan. Aging. 12. PMID 32575074 DOI: 10.18632/aging.103534  0.56
2020 Deuker MM, Lewis KN, Ingaramo M, Kimmel J, Buffenstein R, Settleman J. Unprovoked Stabilization and Nuclear Accumulation of the Naked Mole-Rat p53 Protein. Scientific Reports. 10: 6966. PMID 32332849 DOI: 10.1038/s41598-020-64009-0  0.56
2020 Buffenstein R, Lewis KN, Gibney PA, Narayan V, Grimes KM, Smith M, Lin TD, Brown-Borg HM. Probing Pedomorphy and Prolonged Lifespan in Naked Mole-Rats and Dwarf Mice. Physiology (Bethesda, Md.). 35: 96-111. PMID 32024425 DOI: 10.1152/physiol.00032.2019  0.56
2018 Lewis KN, Rubinstein ND, Buffenstein R. Correction to: A window into extreme longevity; the circulating metabolomic signature of the naked mole-rat, a mammal that shows negligible senescence. Geroscience. PMID 29855760 DOI: 10.1007/s11357-018-0023-1  0.56
2018 Lewis KN, Rubinstein ND, Buffenstein R. A window into extreme longevity; the circulating metabolomic signature of the naked mole-rat, a mammal that shows negligible senescence. Geroscience. PMID 29679203 DOI: 10.1007/s11357-018-0014-2  0.56
2016 Lewis KN, Soifer I, Melamud E, Roy M, McIsaac RS, Hibbs M, Buffenstein R. Unraveling the message: insights into comparative genomics of the naked mole-rat. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 27364349 DOI: 10.1007/s00335-016-9648-5  0.64
2016 Rodriguez KA, Li K, Nevo E, Buffenstein R. Mechanisms regulating proteostasis are involved in sympatric speciation of the blind mole rat, Spalax galili. Autophagy. 12: 703-4. PMID 27050459 DOI: 10.1080/15548627.2016.1143592  0.36
2016 McIsaac RS, Lewis KN, Gibney PA, Buffenstein R. From yeast to human: exploring the comparative biology of methionine restriction in extending eukaryotic life span. Annals of the New York Academy of Sciences. 1363: 155-70. PMID 26995762 DOI: 10.1111/nyas.13032  0.64
2016 Triplett JC, Swomley AM, Kirk J, Grimes KM, Lewis KN, Orr ME, Rodriguez KA, Cai J, Klein JB, Buffenstein R, Butterfield DA. Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat. Neurochemical Research. PMID 26935741 DOI: 10.1007/s11064-016-1877-1  0.64
2016 Rodriguez KA, Valentine JM, Kramer DA, Gelfond JA, Kristan DM, Nevo E, Buffenstein R. Determinants of rodent longevity in the chaperone-protein degradation network. Cell Stress & Chaperones. PMID 26894765 DOI: 10.1007/s12192-016-0672-x  0.64
2015 Gelfond JA, Ibrahim JG, Chen MH, Sun W, Lewis K, Kinahan S, Hibbs M, Buffenstein R. Homology cluster differential expression analysis for interspecies mRNA-Seq experiments. Statistical Applications in Genetics and Molecular Biology. PMID 26595407 DOI: 10.1515/sagmb-2014-0056  0.64
2015 Ma S, Lee SG, Kim EB, Park TJ, Seluanov A, Gorbunova V, Buffenstein R, Seravalli J, Gladyshev VN. Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity. Cell Reports. PMID 26549444 DOI: 10.1016/j.celrep.2015.10.014  0.64
2015 Li K, Hong W, Jiao H, Wang GD, Rodriguez KA, Buffenstein R, Zhao Y, Nevo E, Zhao H. Sympatric speciation revealed by genome-wide divergence in the blind mole rat Spalax. Proceedings of the National Academy of Sciences of the United States of America. 112: 11905-10. PMID 26340990 DOI: 10.1073/pnas.1514896112  0.64
2015 Triplett JC, Tramutola A, Swomley A, Kirk J, Grimes K, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Perluigi M, Buffenstein R, Butterfield DA. Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity. Biochimica Et Biophysica Acta. 1852: 2213-24. PMID 26248058 DOI: 10.1016/j.bbadis.2015.08.002  0.64
2015 Ma S, Yim SH, Lee SG, Kim EB, Lee SR, Chang KT, Buffenstein R, Lewis KN, Park TJ, Miller RA, Clish CB, Gladyshev VN. Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity. Cell Metabolism. 22: 332-43. PMID 26244935 DOI: 10.1016/j.cmet.2015.07.005  0.64
2015 Triplett JC, Swomley A, Kirk J, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Buffenstein R, Butterfield DA. Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat. Journal of Neurochemistry. 134: 538-50. PMID 25940666 DOI: 10.1111/jnc.13149  0.64
2015 Garbarino VR, Orr ME, Rodriguez KA, Buffenstein R. Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates. Archives of Biochemistry and Biophysics. 576: 8-16. PMID 25841340 DOI: 10.1016/j.abb.2015.01.029  0.64
2015 Lewis KN, Wason E, Edrey YH, Kristan DM, Nevo E, Buffenstein R. Regulation of Nrf2 signaling and longevity in naturally long-lived rodents. Proceedings of the National Academy of Sciences of the United States of America. 112: 3722-7. PMID 25775529 DOI: 10.1073/pnas.1417566112  0.64
2015 Fushan AA, Turanov AA, Lee SG, Kim EB, Lobanov AV, Yim SH, Buffenstein R, Lee SR, Chang KT, Rhee H, Kim JS, Yang KS, Gladyshev VN. Gene expression defines natural changes in mammalian lifespan. Aging Cell. 14: 352-65. PMID 25677554 DOI: 10.1111/acel.12283  0.64
2015 Pride H, Yu Z, Sunchu B, Mochnick J, Coles A, Zhang Y, Buffenstein R, Hornsby PJ, Austad SN, Pérez VI. Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species. Biochemical and Biophysical Research Communications. 457: 669-75. PMID 25615820 DOI: 10.1016/j.bbrc.2015.01.046  0.64
2015 Orr ME, Garbarino VR, Salinas A, Buffenstein R. Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent. Neurobiology of Aging. 36: 1496-504. PMID 25576082 DOI: 10.1016/j.neurobiolaging.2014.12.004  0.64
2015 Speakman JR, Blount JD, Bronikowski AM, Buffenstein R, Isaksson C, Kirkwood TBL, Monaghan P, Ozanne SE, Beaulieu M, Briga M, Carr SK, Christensen LL, Cochemé HM, Cram DL, Dantzer B, et al. Oxidative stress and life histories: Unresolved issues and current needs Ecology and Evolution. DOI: 10.1002/ece3.1790  0.64
2014 Rodriguez KA, Dodds SG, Strong R, Galvan V, Sharp ZD, Buffenstein R. Divergent tissue and sex effects of rapamycin on the proteasome-chaperone network of old mice. Frontiers in Molecular Neuroscience. 7: 83. PMID 25414638 DOI: 10.3389/fnmol.2014.00083  0.32
2014 Fang X, Seim I, Huang Z, Gerashchenko MV, Xiong Z, Turanov AA, Zhu Y, Lobanov AV, Fan D, Yim SH, Yao X, Ma S, Yang L, Lee SG, Kim EB, ... ... Buffenstein R, et al. Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes. Cell Reports. 8: 1354-64. PMID 25176646 DOI: 10.1016/j.celrep.2014.07.030  0.64
2014 Rodriguez KA, Osmulski PA, Pierce A, Weintraub ST, Gaczynska M, Buffenstein R. A cytosolic protein factor from the naked mole-rat activates proteasomes of other species and protects these from inhibition. Biochimica Et Biophysica Acta. 1842: 2060-72. PMID 25018089 DOI: 10.1016/j.bbadis.2014.07.005  0.64
2014 Grimes KM, Reddy AK, Lindsey ML, Buffenstein R. And the beat goes on: maintained cardiovascular function during aging in the longest-lived rodent, the naked mole-rat. American Journal of Physiology. Heart and Circulatory Physiology. 307: H284-91. PMID 24906918 DOI: 10.1152/ajpheart.00305.2014  0.64
2014 Ables GP, Brown-Borg HM, Buffenstein R, Church CD, Elshorbagy AK, Gladyshev VN, Huang TH, Miller RA, Mitchell JR, Richie JP, Rogina B, Stipanuk MH, Orentreich DS, Orentreich N. The first international mini-symposium on methionine restriction and lifespan. Frontiers in Genetics. 5: 122. PMID 24847356 DOI: 10.3389/fgene.2014.00122  0.64
2014 Orr ME, Salinas A, Buffenstein R, Oddo S. Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology. Neurobiology of Aging. 35: 1233-42. PMID 24411482 DOI: 10.1016/j.neurobiolaging.2013.12.006  0.64
2014 Grimes KM, Voorhees A, Chiao YA, Han HC, Lindsey ML, Buffenstein R. Cardiac function of the naked mole-rat: ecophysiological responses to working underground. American Journal of Physiology. Heart and Circulatory Physiology. 306: H730-7. PMID 24363308 DOI: 10.1152/ajpheart.00831.2013  0.64
2014 Edrey YH, Oddo S, Cornelius C, Caccamo A, Calabrese V, Buffenstein R. Oxidative damage and amyloid-β metabolism in brain regions of the longest-lived rodents. Journal of Neuroscience Research. 92: 195-205. PMID 24273049 DOI: 10.1002/jnr.23320  0.64
2014 Rodriguez KA, Dodds SG, Strong R, Galvan V, Sharp ZD, Buffenstein R. Divergent tissue and sex effects of rapamycin on the proteasome-chaperone network of old mice Frontiers in Molecular Neuroscience. 7: 1-17. DOI: 10.3389/fnmol.2014.00083  0.64
2013 Hamilton RT, Bhattacharya A, Walsh ME, Shi Y, Wei R, Zhang Y, Rodriguez KA, Buffenstein R, Chaudhuri AR, Van Remmen H. Elevated protein carbonylation, and misfolding in sciatic nerve from db/db and Sod1(-/-) mice: plausible link between oxidative stress and demyelination. Plos One. 8: e65725. PMID 23750273 DOI: 10.1371/journal.pone.0065725  0.64
2013 Edrey YH, Medina DX, Gaczynska M, Osmulski PA, Oddo S, Caccamo A, Buffenstein R. Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease. Neurobiology of Aging. 34: 2352-60. PMID 23618870 DOI: 10.1016/j.neurobiolaging.2013.03.032  0.64
2013 De Waal EM, Liang H, Pierce A, Hamilton RT, Buffenstein R, Chaudhuri AR. Elevated protein carbonylation and oxidative stress do not affect protein structure and function in the long-living naked-mole rat: a proteomic approach. Biochemical and Biophysical Research Communications. 434: 815-9. PMID 23618867 DOI: 10.1016/j.bbrc.2013.04.019  0.64
2013 Shi Y, Pulliam DA, Liu Y, Hamilton RT, Jernigan AL, Bhattacharya A, Sloane LB, Qi W, Chaudhuri A, Buffenstein R, Ungvari Z, Austad SN, Van Remmen H. Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 304: R343-55. PMID 23325454 DOI: 10.1152/ajpregu.00139.2012  0.64
2013 Lewis KN, Andziak B, Yang T, Buffenstein R. The naked mole-rat response to oxidative stress: just deal with it. Antioxidants & Redox Signaling. 19: 1388-99. PMID 23025341 DOI: 10.1089/ars.2012.4911  0.56
2012 Lewis KN, Mele J, Hornsby PJ, Buffenstein R. Stress resistance in the naked mole-rat: the bare essentials - a mini-review. Gerontology. 58: 453-62. PMID 22572398 DOI: 10.1159/000335966  0.64
2012 Rodriguez KA, Edrey YH, Osmulski P, Gaczynska M, Buffenstein R. Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat. Plos One. 7: e35890. PMID 22567116 DOI: 10.1371/journal.pone.0035890  0.64
2012 Peterson BL, Larson J, Buffenstein R, Park TJ, Fall CP. Blunted neuronal calcium response to hypoxia in naked mole-rat hippocampus. Plos One. 7: e31568. PMID 22363676 DOI: 10.1371/journal.pone.0031568  0.64
2012 Edrey YH, Casper D, Huchon D, Mele J, Gelfond JA, Kristan DM, Nevo E, Buffenstein R. Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity. Aging Cell. 11: 213-22. PMID 22103690 DOI: 10.1111/j.1474-9726.2011.00772.x  0.64
2012 Buffenstein R, Park T, Hanes M, Artwohl JE. Naked Mole Rat The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents. 1055-1074. DOI: 10.1016/B978-0-12-380920-9.00045-6  0.64
2011 Kim EB, Fang X, Fushan AA, Huang Z, Lobanov AV, Han L, Marino SM, Sun X, Turanov AA, Yang P, Yim SH, Zhao X, Kasaikina MV, Stoletzki N, Peng C, ... ... Buffenstein R, et al. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Nature. 479: 223-7. PMID 21993625 DOI: 10.1038/nature10533  0.64
2011 Rodriguez KA, Wywial E, Perez VI, Lambert AJ, Edrey YH, Lewis KN, Grimes K, Lindsey ML, Brand MD, Buffenstein R. Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent. Current Pharmaceutical Design. 17: 2290-307. PMID 21736541  0.64
2011 Bhattacharya A, Leonard S, Tardif S, Buffenstein R, Fischer KE, Richardson A, Austad SN, Chaudhuri AR. Attenuation of liver insoluble protein carbonyls: indicator of a longevity determinant? Aging Cell. 10: 720-3. PMID 21463461 DOI: 10.1111/j.1474-9726.2011.00712.x  0.64
2011 Edrey YH, Hanes M, Pinto M, Mele J, Buffenstein R. Successful aging and sustained good health in the naked mole rat: a long-lived mammalian model for biogerontology and biomedical research. Ilar Journal. 52: 41-53. PMID 21411857  0.64
2011 Edrey YH, Park TJ, Kang H, Biney A, Buffenstein R. Endocrine function and neurobiology of the longest-living rodent, the naked mole-rat. Experimental Gerontology. 46: 116-23. PMID 20888895 DOI: 10.1016/j.exger.2010.09.005  0.64
2010 Lewis KN, Mele J, Hayes JD, Buffenstein R. Nrf2, a guardian of healthspan and gatekeeper of species longevity. Integrative and Comparative Biology. 50: 829-43. PMID 21031035 DOI: 10.1093/icb/icq034  0.64
2010 Liang S, Mele J, Wu Y, Buffenstein R, Hornsby PJ. Resistance to experimental tumorigenesis in cells of a long-lived mammal, the naked mole-rat (Heterocephalus glaber). Aging Cell. 9: 626-35. PMID 20550519 DOI: 10.1111/j.1474-9726.2010.00588.x  0.64
2010 Pinto M, Jepsen KJ, Terranova CJ, Buffenstein R. Lack of sexual dimorphism in femora of the eusocial and hypogonadic naked mole-rat: A novel animal model for the study of delayed puberty on the skeletal system Bone. 46: 112-120. PMID 19761882 DOI: 10.1016/j.bone.2009.08.060  0.64
2010 Mele J, Edrey YH, Lewis KN, Buffenstein R. Mechanisms of aging in the naked mole-rat: The case for programmed aging Russian Journal of General Chemistry. 80: 1455-1464. DOI: 10.1134/S1070363210070418  0.64
2009 Pérez VI, Buffenstein R, Masamsetti V, Leonard S, Salmon AB, Mele J, Andziak B, Yang T, Edrey Y, Friguet B, Ward W, Richardson A, Chaudhuri A. Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat. Proceedings of the National Academy of Sciences of the United States of America. 106: 3059-64. PMID 19223593 DOI: 10.1073/pnas.0809620106  0.56
2009 Buffenstein R, Pinto M. Endocrine function in naturally long-living small mammals. Molecular and Cellular Endocrinology. 299: 101-11. PMID 18674586 DOI: 10.1016/j.mce.2008.04.021  0.32
2008 Buffenstein R, Edrey YH, Yang T, Mele J. The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms. Age (Dordrecht, Netherlands). 30: 99-109. PMID 19424860 DOI: 10.1007/s11357-008-9058-z  0.64
2008 Ungvari Z, Buffenstein R, Austad SN, Podlutsky A, Kaley G, Csiszar A. Oxidative stress in vascular senescence: lessons from successfully aging species. Frontiers in Bioscience : a Journal and Virtual Library. 13: 5056-70. PMID 18508570 DOI: 10.2741/3064  0.64
2008 Buffenstein R, Edrey YH, Larsen PL. Animal models in aging research: A critical examination Source Book of Models For Biomedical Research. 499-506. DOI: 10.1007/978-1-59745-285-4_52  0.64
2007 Hulbert AJ, Pamplona R, Buffenstein R, Buttemer WA. Life and death: metabolic rate, membrane composition, and life span of animals. Physiological Reviews. 87: 1175-213. PMID 17928583 DOI: 10.1152/physrev.00047.2006  0.64
2007 Lambert AJ, Boysen HM, Buckingham JA, Yang T, Podlutsky A, Austad SN, Kunz TH, Buffenstein R, Brand MD. Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms. Aging Cell. 6: 607-18. PMID 17596208 DOI: 10.1111/j.1474-9726.2007.00312.x  0.64
2006 Xiao J, Levitt JB, Buffenstein R. A stereotaxic atlas of the brain of the naked mole-rat (Heterocephalus glaber). Neuroscience. 141: 1415-35. PMID 16793211 DOI: 10.1016/j.neuroscience.2006.03.077  0.64
2006 Hulbert AJ, Faulks SC, Harper JM, Miller RA, Buffenstein R. Extended longevity of wild-derived mice is associated with peroxidation-resistant membranes. Mechanisms of Ageing and Development. 127: 653-7. PMID 16620917 DOI: 10.1016/j.mad.2006.03.002  0.64
2006 Xiao J, Levitt JB, Buffenstein R. The use of a novel and simple method of revealing neural fibers to show the regression of the lateral geniculate nucleus in the naked mole-rat (Heterocephalus glaber). Brain Research. 1077: 81-9. PMID 16483554 DOI: 10.1016/j.brainres.2006.01.021  0.64
1998 Daly TJM, Buffenstein R. Skin morphology and its role in thermoregulation in mole-rats, Heterocephalus glaber and Cryptomys hottentotus Journal of Anatomy. 193: 495-502. PMID 10029182 DOI: 10.1046/j.1469-7580.1998.19340495.x  0.64
1991 Buffenstein R, Skinner DC, Yahav S, Moodley GP, Cavaleros M, Zachen D, Ross FP, Pettifor JM. Effect of oral cholecalciferol supplementation at physiological and supraphysiological doses in naturally vitamin D3-deficient subterranean damara mole rate (Cryptomys damarensis) Journal of Endocrinology. 131: 197-202. PMID 1660517 DOI: 10.1677/joe.0.1310197  0.64
1991 Skinner DC, Moodley G, Buffenstein R. Is vitamin D3 essential for mineral metabolism in the Damara mole-rat (Cryptomys damarensis)? General and Comparative Endocrinology. 81: 500-505. PMID 1647351 DOI: 10.1016/0016-6480(91)90178-9  0.64
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