William L. Dewey - Publications

Affiliations: 
Virginia Commonwealth University School of Medicine, Richmond, VA 
Area:
pharmacology, analgesics, opioids

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Year Citation  Score
2020 Sierra S, Lippold KM, Stevens DL, Poklis JL, Dewey WL, González-Maeso J. Adjunctive effect of the serotonin 5-HT receptor agonist lorcaserin on opioid-induced antinociception in mice. Neuropharmacology. 107949. PMID 31987863 DOI: 10.1016/j.neuropharm.2020.107949  0.416
2019 Mischel RA, Muchhala KH, Dewey WL, Akbarali HI. The "culture" of pain control: A review of opioid-induced dysbiosis (OID) in antinociceptive tolerance. The Journal of Pain : Official Journal of the American Pain Society. PMID 31841668 DOI: 10.1016/J.Jpain.2019.11.015  0.347
2019 Ma H, Obeng S, Wang H, Zheng Y, Li M, Jali AM, Stevens D, Dewey WL, Selley DE, Zhang Y. Application of Bivalent Bioisostere Concept on Design and Discovery of Potent Opioid Receptor Modulators. Journal of Medicinal Chemistry. PMID 31782922 DOI: 10.1021/Acs.Jmedchem.9B01767  0.403
2019 Hill R, Roberts J, Maclachlan J, Dewey W, Kelly E, Henderson G. Prolonged ethanol administration prevents the development of tolerance to morphine-induced respiratory depression. Drug and Alcohol Dependence. 205: 107674. PMID 31715438 DOI: 10.1016/j.drugalcdep.2019.107674  0.313
2019 Hill R, Santhakumar R, Dewey W, Kelly E, Henderson G. Fentanyl depression of respiration: comparison with heroin and morphine. British Journal of Pharmacology. PMID 31499594 DOI: 10.1111/Bph.14860  0.322
2019 Komla E, Stevens DL, Zheng Y, Zhang Y, Dewey WL, Akbarali HI. Experimental colitis enhances the rate of antinociceptive tolerance to morphine via peripheral opioid receptors. The Journal of Pharmacology and Experimental Therapeutics. PMID 31248978 DOI: 10.1124/Jpet.119.256941  0.415
2019 Akbarali HI, Dewey WL. Gastrointestinal motility, dysbiosis and opioid-induced tolerance: is there a link? Nature Reviews. Gastroenterology & Hepatology. PMID 31024090 DOI: 10.1038/S41575-019-0150-X  0.359
2019 Obeng S, Jali A, Zheng Y, Wang H, Schwienteck K, Chen C, Stevens DL, Akbarali H, Dewey WL, Banks ML, Liu-Chen LY, Selley DE, Zhang Y. Characterization of 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-carboxamido)morphinan (NAN) as a Novel Opioid Receptor Modulator for Opioid Use Disorder Treatment. Acs Chemical Neuroscience. PMID 30758946 DOI: 10.1021/Acschemneuro.9B00038  0.391
2019 Zheng Y, Obeng S, Wang H, Jali AM, Peddibhotla B, Williams D, Zou C, Stevens DL, Dewey WL, Akbarali HI, Selley DE, Zhang Y. Design, Synthesis, and Biological Evaluation of the Third Generation 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'- pyridyl)carboxamido]morphinan (NAP) Derivatives as Mu/Kappa Opioid Receptor Dual Selective Ligands. Journal of Medicinal Chemistry. PMID 30608693 DOI: 10.1021/Acs.Jmedchem.8B01158  0.391
2018 Obeng S, Wang H, Jali A, Stevens DL, Akbarali HI, Dewey WL, Selley DE, Zhang Y. Structure activity relationship studies of 6α- and 6β-indolylacetamidonaltrexamine derivatives as bitopic mu opioid receptor modulators and elaboration of the 'message-address concept' to comprehend their functional conversion. Acs Chemical Neuroscience. PMID 30156823 DOI: 10.1021/Acschemneuro.8B00349  0.335
2018 Zheng Y, Obeng S, Wang H, Stevens DL, Komla E, Selley DE, Dewey WL, Akbarali HI, Zhang Y. Methylation Products of 6β-N-heterocyclic substituted naltrexamine derivatives as potential peripheral opioid receptor modulators. Acs Chemical Neuroscience. PMID 30001114 DOI: 10.1021/Acschemneuro.8B00234  0.382
2018 Mischel RA, Dewey WL, Akbarali HI. Tolerance to Morphine-Induced Inhibition of TTX-R Sodium Channels in Dorsal Root Ganglia Neurons Is Modulated by Gut-Derived Mediators. Iscience. 2: 193-209. PMID 29888757 DOI: 10.1016/J.Isci.2018.03.003  0.356
2018 Hill R, Disney A, Conibear A, Sutcliffe K, Dewey W, Husbands S, Bailey C, Kelly E, Henderson G. The novel μ-opioid receptor agonist PZM21 depresses respiration and induces tolerance to antinociception. British Journal of Pharmacology. PMID 29582414 DOI: 10.1111/bph.14224  0.342
2018 Hill R, Dewey WL, Kelly E, Henderson G. Oxycodone-induced Tolerance to Respiratory Depression: Reversal by Ethanol, Pregabalin, and Protein Kinase C Inhibition. British Journal of Pharmacology. PMID 29574756 DOI: 10.1111/bph.14219  0.352
2018 Jacob JC, Sakakibara K, Mischel RA, Henderson G, Dewey WL, Akbarali HI. Ethanol Reversal of Oxycodone Tolerance in Dorsal Root Ganglia Neurons. Molecular Pharmacology. PMID 29467238 DOI: 10.1124/Mol.117.110775  0.317
2018 Jacob JC, David B, Khan A, Dewey WL, Akbarali HI. Mo1578 - The Effect of a G-Protein Biased Ligand, TRV130, on Opioid-Induced Constipation Gastroenterology. 154: S-758. DOI: 10.1016/S0016-5085(18)32629-5  0.312
2017 Gonek M, McLane VD, Stevens DL, Lippold K, Akbarali HI, Knapp PE, Dewey WL, Hauser KF, Paris JJ. CCR5 mediates HIV-1 Tat-induced neuroinflammation and influences morphine tolerance, dependence, and reward. Brain, Behavior, and Immunity. PMID 29146238 DOI: 10.1016/J.Bbi.2017.11.006  0.401
2017 Akbarali HI, Dewey WL. The gut-brain interaction in opioid tolerance. Current Opinion in Pharmacology. 37: 126-130. PMID 29145012 DOI: 10.1016/J.Coph.2017.10.012  0.355
2017 Gonek M, Akbarali HI, Henderson G, Dewey WL. Reversal of Oxycodone and Hydrocodone Tolerance by Diazepam. Brain Research. PMID 28830768 DOI: 10.1016/J.Brainres.2017.08.017  0.389
2017 Jacob JC, Poklis JL, Akbarali HI, Henderson G, Dewey WL. Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone. The Journal of Pharmacology and Experimental Therapeutics. PMID 28442580 DOI: 10.1124/Jpet.117.241083  0.344
2017 Bhave S, Gade A, Kang M, Hauser KF, Dewey WL, Akbarali HI. Connexin-purinergic signaling in enteric glia mediates the prolonged effect of morphine on constipation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28280004 DOI: 10.1096/Fj.201601068R  0.38
2017 Kang M, Mischel RA, Bhave S, Komla E, Cho A, Huang C, Dewey WL, Akbarali HI. The effect of gut microbiome on tolerance to morphine mediated antinociception in mice. Scientific Reports. 7: 42658. PMID 28211545 DOI: 10.1038/Srep42658  0.403
2017 Withey SL, Hill R, Lyndon A, Dewey WL, Kelly E, Henderson G. Effect of tamoxifen and brain penetrant PKC and JNK inhibitors on tolerance to opioid-induced respiratory depression in mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 28130265 DOI: 10.1124/Jpet.116.238329  0.4
2017 Xu GG, Zolotarskaya OY, Williams DA, Yuan Y, Selley DE, Dewey WL, Akbarali HI, Yang H, Zhang Y. Nanoconjugated NAP as a Potent and Periphery Selective Mu Opioid Receptor Modulator To Treat Opioid-Induced Constipation. Acs Medicinal Chemistry Letters. 8: 78-83. PMID 28105279 DOI: 10.1021/Acsmedchemlett.6B00382  0.369
2017 Mischel R, Dewey WL, Akbarali HI. Colonic Supernatants from Chronic Morphine Exposed Mice Induce Morphine Tolerance in Naïve Dorsal Root Ganglion Neurons that is Mitigated by Oral Vancomycin Delivery Gastroenterology. 152: S730. DOI: 10.1016/S0016-5085(17)32537-4  0.378
2017 Muchhala K, Gade A, Dewey WL, Akbarali HI. μ-Opioid Receptors Co-Expressed in Cholinergic Neurons of Mouse Ileum Myenteric Plexus Develop Tolerance to Chronic Morphine Exposure Gastroenterology. 152: S710. DOI: 10.1016/S0016-5085(17)32478-2  0.354
2017 Lippold K, Dewey W. The Role of 5-HT2a/2c Receptors in Nociception and Opioid Antinociception: a Review of the Preclinical Literature Current Treatment Options in Psychiatry. 4: 210-220. DOI: 10.1007/s40501-017-0111-3  0.362
2016 Williams DA, Zheng Y, David BG, Yuan Y, Zaidi SA, Stevens DL, Scoggins KL, Selley DE, Dewey WL, Akbarali HI, Zhang Y. 6β-N-Heterocyclic Substituted Naltrexamine Derivative BNAP: A Peripherally Selective Mixed MOR/KOR Ligand. Acs Chemical Neuroscience. PMID 27269866 DOI: 10.1021/Acschemneuro.6B00075  0.384
2016 Gade AR, Kang M, Khan F, Grider JR, Damaj MI, Dewey WL, Akbarali HI. Enhanced sensitivity of α3β4 nicotinic receptors in enteric neurons after chronic morphine: implication for opioid-induced constipation. The Journal of Pharmacology and Experimental Therapeutics. PMID 27068812 DOI: 10.1124/Jpet.116.233304  0.34
2016 Wilkerson JL, Niphakis MJ, Grim TW, Mustafa MA, Abdullah RA, Poklis JL, Dewey WL, Akbarali HI, Banks ML, Wise LE, Cravatt BF, Lichtman AH. The selective monoacylglycerol lipase inhibitor MJN110 produces opioid sparing effects in a mouse neuropathic pain model. The Journal of Pharmacology and Experimental Therapeutics. PMID 26791602 DOI: 10.1124/Jpet.115.229971  0.547
2016 Akbarali HI, Kang M, Mischel R, Bhave S, Gade A, Sakakibara K, Komla E, Muchhala K, Dewey W. Su1940 The Role of the Gastrointestinal Microbiota in Opioid-Induced Analgesic Tolerance Gastroenterology. 150: S594-S595. DOI: 10.1016/S0016-5085(16)32039-X  0.355
2015 Zhang Y, Williams DA, Zaidi SA, Yuan Y, Braithwaite A, Bilsky EJ, Dewey WL, Akbarali HI, Streicher JM, Selley DE. 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP) modulating the mu opioid receptor in a biased fashion. Acs Chemical Neuroscience. PMID 26716358 DOI: 10.1021/Acschemneuro.5B00245  0.327
2015 Fitting S, Stevens DL, Khan FA, Scoggins KL, Enga RM, Beardsley PM, Knapp PE, Dewey WL, Hauser KF. Morphine tolerance and physical dependence are altered in conditional HIV-1 Tat transgenic mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 26542403 DOI: 10.1124/Jpet.115.226407  0.36
2015 Yuan Y, Zaidi SA, Stevens DL, Scoggins KL, Mosier PD, Kellogg GE, Dewey WL, Selley DE, Zhang Y. Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligands. Bioorganic & Medicinal Chemistry. 23: 1701-15. PMID 25783191 DOI: 10.1016/J.Bmc.2015.02.055  0.366
2014 Akbarali HI, Inkisar A, Dewey WL. Site and mechanism of morphine tolerance in the gastrointestinal tract. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 26: 1361-7. PMID 25257923 DOI: 10.1111/Nmo.12443  0.381
2014 Smith TH, Ngwainmbi J, Hashimoto A, Dewey WL, Akbarali HI. Morphine dependence in single enteric neurons from the mouse colon requires deletion of β-arrestin2. Physiological Reports. 2. PMID 25194025 DOI: 10.14814/Phy2.12140  0.35
2013 Yuan Y, Zaidi SA, Elbegdorj O, Aschenbach LC, Li G, Stevens DL, Scoggins KL, Dewey WL, Selley DE, Zhang Y. Design, synthesis, and biological evaluation of 14-heteroaromatic-substituted naltrexone derivatives: pharmacological profile switch from mu opioid receptor selectivity to mu/kappa opioid receptor dual selectivity. Journal of Medicinal Chemistry. 56: 9156-69. PMID 24144240 DOI: 10.1021/Jm4012214  0.351
2013 Llorente J, Withey S, Rivero G, Cunningham M, Cooke A, Saxena K, McPherson J, Oldfield S, Dewey WL, Bailey CP, Kelly E, Henderson G. Ethanol reversal of cellular tolerance to morphine in rat locus coeruleus neurons. Molecular Pharmacology. 84: 252-60. PMID 23716621 DOI: 10.1124/Mol.113.085936  0.341
2013 Hull LC, Gabra BH, Bailey CP, Henderson G, Dewey WL. Reversal of morphine analgesic tolerance by ethanol in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 345: 512-9. PMID 23528610 DOI: 10.1124/jpet.112.202184  0.367
2012 Yuan Y, Elbegdorj O, Chen J, Akubathini SK, Zhang F, Stevens DL, Beletskaya IO, Scoggins KL, Zhang Z, Gerk PM, Selley DE, Akbarali HI, Dewey WL, Zhang Y. Design, synthesis, and biological evaluation of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'-pyridyl)carboxamido]morphinan derivatives as peripheral selective μ opioid receptor Agents. Journal of Medicinal Chemistry. 55: 10118-29. PMID 23116124 DOI: 10.1021/Jm301247N  0.409
2012 Smith TH, Grider JR, Dewey WL, Akbarali HI. Morphine decreases enteric neuron excitability via inhibition of sodium channels. Plos One. 7: e45251. PMID 23028881 DOI: 10.1371/Journal.Pone.0045251  0.32
2012 Ritter JK, Fang Y, Xia M, Li PL, Dewey WL. Contribution of acid sphingomyelinase in the periaqueductal gray region to morphine-induced analgesia in mice. Neuroreport. 23: 780-5. PMID 22825003 DOI: 10.1097/Wnr.0B013E3283571757  0.409
2012 Ross GR, Lichtman A, Dewey WL, Akbarali HI. Evidence for the putative cannabinoid receptor (GPR55)-mediated inhibitory effects on intestinal contractility in mice. Pharmacology. 90: 55-65. PMID 22759743 DOI: 10.1159/000339076  0.521
2012 Ritter JK, Li C, Xia M, Poklis JL, Lichtman AH, Abdullah RA, Dewey WL, Li PL. Production and actions of the anandamide metabolite prostamide E2 in the renal medulla. The Journal of Pharmacology and Experimental Therapeutics. 342: 770-9. PMID 22685343 DOI: 10.1124/Jpet.112.196451  0.463
2012 Yuan Y, Stevens DL, Braithwaite A, Scoggins KL, Bilsky EJ, Akbarali HI, Dewey WL, Zhang Y. 6β-N-heterocyclic substituted naltrexamine derivative NAP as a potential lead to develop peripheral mu opioid receptor selective antagonists. Bioorganic & Medicinal Chemistry Letters. 22: 4731-4. PMID 22683223 DOI: 10.1016/J.Bmcl.2012.05.075  0.428
2012 Fitting S, Scoggins KL, Xu R, Dever SM, Knapp PE, Dewey WL, Hauser KF. Morphine efficacy is altered in conditional HIV-1 Tat transgenic mice. European Journal of Pharmacology. 689: 96-103. PMID 22659585 DOI: 10.1016/J.Ejphar.2012.05.029  0.327
2012 Maguma HT, Dewey WL, Akbarali HI. Differences in the characteristics of tolerance to μ-opioid receptor agonists in the colon from wild type and β-arrestin2 knockout mice. European Journal of Pharmacology. 685: 133-40. PMID 22521552 DOI: 10.1016/J.Ejphar.2012.04.001  0.386
2012 Ross GR, Gade AR, Dewey WL, Akbarali HI. Opioid-induced hypernociception is associated with hyperexcitability and altered tetrodotoxin-resistant Na+ channel function of dorsal root ganglia. American Journal of Physiology. Cell Physiology. 302: C1152-61. PMID 22189556 DOI: 10.1152/Ajpcell.00171.2011  0.333
2012 Kang M, Maguma HT, Smith TH, Ross GR, Dewey WL, Akbarali HI. The role of β-arrestin2 in the mechanism of morphine tolerance in the mouse and guinea pig gastrointestinal tract. The Journal of Pharmacology and Experimental Therapeutics. 340: 567-76. PMID 22129596 DOI: 10.1124/Jpet.111.186320  0.396
2011 Yuan Y, Li G, He H, Stevens DL, Kozak P, Scoggins KL, Mitra P, Gerk PM, Selley DE, Dewey WL, Zhang Y. Characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives as novel leads to development of mu opioid receptor selective antagonists. Acs Chemical Neuroscience. 2: 346-51. PMID 22816021 DOI: 10.1021/Cn2000348  0.368
2011 Hoot MR, Sim-Selley LJ, Selley DE, Scoggins KL, Dewey WL. Chronic neuropathic pain in mice reduces μ-opioid receptor-mediated G-protein activity in the thalamus. Brain Research. 1406: 1-7. PMID 21762883 DOI: 10.1016/J.Brainres.2011.06.023  0.369
2010 McPherson J, Rivero G, Baptist M, Llorente J, Al-Sabah S, Krasel C, Dewey WL, Bailey CP, Rosethorne EM, Charlton SJ, Henderson G, Kelly E. μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization. Molecular Pharmacology. 78: 756-66. PMID 20647394 DOI: 10.1124/mol.110.066613  0.34
2010 Hull LC, Rabender C, Gabra BH, Zhang F, Li PL, Dewey WL. Role of CD38, a cyclic ADP-ribosylcyclase, in morphine antinociception and tolerance. The Journal of Pharmacology and Experimental Therapeutics. 334: 1042-50. PMID 20551293 DOI: 10.1124/Jpet.110.169243  0.355
2010 Hoot MR, Sim-Selley LJ, Poklis JL, Abdullah RA, Scoggins KL, Selley DE, Dewey WL. Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice. Brain Research. 1339: 18-25. PMID 20380816 DOI: 10.1016/J.Brainres.2010.03.105  0.308
2010 Hull LC, Llorente J, Gabra BH, Smith FL, Kelly E, Bailey C, Henderson G, Dewey WL. The effect of protein kinase C and G protein-coupled receptor kinase inhibition on tolerance induced by mu-opioid agonists of different efficacy. The Journal of Pharmacology and Experimental Therapeutics. 332: 1127-35. PMID 20008489 DOI: 10.1124/jpet.109.161455  0.396
2009 Bailey CP, Oldfield S, Llorente J, Caunt CJ, Teschemacher AG, Roberts L, McArdle CA, Smith FL, Dewey WL, Kelly E, Henderson G. Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons. British Journal of Pharmacology. 158: 157-64. PMID 19309357 DOI: 10.1111/j.1476-5381.2009.00140.x  0.38
2009 Bailey CP, Llorente J, Gabra BH, Smith FL, Dewey WL, Kelly E, Henderson G. Role of protein kinase C and mu-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons. The European Journal of Neuroscience. 29: 307-18. PMID 19200236 DOI: 10.1111/j.1460-9568.2008.06573.x  0.406
2009 Li G, Aschenbach LC, Chen J, Cassidy MP, Stevens DL, Gabra BH, Selley DE, Dewey WL, Westkaemper RB, Zhang Y. Design, synthesis, and biological evaluation of 6alpha- and 6beta-N-heterocyclic substituted naltrexamine derivatives as mu opioid receptor selective antagonists. Journal of Medicinal Chemistry. 52: 1416-27. PMID 19199782 DOI: 10.1021/Jm801272C  0.355
2009 Li G, Aschenbach LC, Chen J, Cassidy MP, Stevens DL, Gabra BH, Selley DE, Dewey WL, Westkaemper RB, Zhang Y. Corrections to design, synthesis, and biological evaluation of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives as μ opioid receptor selective antagonists (Journal of Medicinal Chemistry (2009) 52, (1416) DOI 10.1021/jm801272c) Journal of Medicinal Chemistry. 52: 8057. DOI: 10.1021/Jm9016224  0.313
2008 Ross GR, Gabra BH, Dewey WL, Akbarali HI. Morphine tolerance in the mouse ileum and colon. The Journal of Pharmacology and Experimental Therapeutics. 327: 561-72. PMID 18682567 DOI: 10.1124/Jpet.108.143438  0.401
2008 Gabra BH, Bailey CP, Kelly E, Smith FL, Henderson G, Dewey WL. Pre-treatment with a PKC or PKA inhibitor prevents the development of morphine tolerance but not physical dependence in mice. Brain Research. 1217: 70-7. PMID 18501877 DOI: 10.1016/j.brainres.2008.04.036  0.411
2008 Gabra BH, Smith FL, Navarro HA, Carroll FI, Dewey WL. mGluR5 antagonists that block calcium mobilization in vitro also reverse (S)-3,5-DHPG-induced hyperalgesia and morphine antinociceptive tolerance in vivo. Brain Research. 1187: 58-66. PMID 18022146 DOI: 10.1016/j.brainres.2007.10.007  0.435
2007 Gabra BH, Bailey CP, Kelly E, Sanders AV, Henderson G, Smith FL, Dewey WL. Evidence for an important role of protein phosphatases in the mechanism of morphine tolerance. Brain Research. 1159: 86-93. PMID 17582387 DOI: 10.1016/j.brainres.2007.05.017  0.432
2007 Sim-Selley LJ, Scoggins KL, Cassidy MP, Smith LA, Dewey WL, Smith FL, Selley DE. Region-dependent attenuation of mu opioid receptor-mediated G-protein activation in mouse CNS as a function of morphine tolerance. British Journal of Pharmacology. 151: 1324-33. PMID 17572699 DOI: 10.1038/Sj.Bjp.0707328  0.421
2007 Gabra BH, Kessler FK, Ritter JK, Dewey WL, Smith FL. Decrease in N-methyl-D-aspartic acid receptor-NR2B subunit levels by intrathecal short-hairpin RNA blocks group I metabotropic glutamate receptor-mediated hyperalgesia. The Journal of Pharmacology and Experimental Therapeutics. 322: 186-94. PMID 17405869 DOI: 10.1124/jpet.107.120071  0.328
2007 Smith FL, Gabra BH, Smith PA, Redwood MC, Dewey WL. Determination of the role of conventional, novel and atypical PKC isoforms in the expression of morphine tolerance in mice. Pain. 127: 129-39. PMID 16965856 DOI: 10.1016/j.pain.2006.08.009  0.406
2006 Smith FL, Javed RR, Smith PA, Dewey WL, Gabra BH. PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 54: 474-80. PMID 17056270 DOI: 10.1016/j.phrs.2006.09.007  0.424
2006 Bailey CP, Smith FL, Kelly E, Dewey WL, Henderson G. How important is protein kinase C in mu-opioid receptor desensitization and morphine tolerance? Trends in Pharmacological Sciences. 27: 558-65. PMID 17000011 DOI: 10.1016/j.tips.2006.09.006  0.392
2006 Martin BR, Wiley JL, Beletskaya I, Sim-Selley LJ, Smith FL, Dewey WL, Cottney J, Adams J, Baker J, Hill D, Saha B, Zerkowski J, Mahadevan A, Razdan RK. Pharmacological characterization of novel water-soluble cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 318: 1230-9. PMID 16757541 DOI: 10.1124/Jpet.106.104109  0.615
2005 Dalton GD, Smith FL, Smith PA, Dewey WL. Protein Kinase A activity is increased in mouse lumbar spinal cord but not brain following morphine antinociceptive tolerance for 15 days. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 52: 204-10. PMID 16026714 DOI: 10.1016/j.phrs.2005.03.004  0.398
2005 Dalton GD, Smith FL, Smith PA, Dewey WL. Chronic Delta9-tetrahydrocannabinol treatment produces antinociceptive tolerance in mice without altering protein kinase A activity in mouse brain and spinal cord. Biochemical Pharmacology. 70: 152-60. PMID 15913565 DOI: 10.1016/j.bcp.2005.04.008  0.34
2005 Dalton GD, Smith FL, Smith PA, Dewey WL. Alterations in brain Protein Kinase A activity and reversal of morphine tolerance by two fragments of native Protein Kinase A inhibitor peptide (PKI). Neuropharmacology. 48: 648-57. PMID 15814100 DOI: 10.1016/j.neuropharm.2004.12.006  0.385
2005 Wiley JL, Smith FL, Razdan RK, Dewey WL. Task specificity of cross-tolerance between Delta9-tetrahydrocannabinol and anandamide analogs in mice. European Journal of Pharmacology. 510: 59-68. PMID 15740725 DOI: 10.1016/J.Ejphar.2005.01.006  0.597
2004 Javed RR, Dewey WL, Smith PA, Smith FL. PKC and PKA inhibitors reverse tolerance to morphine-induced hypothermia and supraspinal analgesia in mice. European Journal of Pharmacology. 492: 149-57. PMID 15178359 DOI: 10.1016/j.ejphar.2004.03.061  0.389
2004 Smith FL, Smith PA, Dewey WL, Javed RR. Effects of mGlu1 and mGlu5 metabotropic glutamate antagonists to reverse morphine tolerance in mice. European Journal of Pharmacology. 492: 137-42. PMID 15178357 DOI: 10.1016/j.ejphar.2004.03.055  0.41
2003 Smith FL, Javed RR, Elzey MJ, Dewey WL. The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA. Brain Research. 985: 78-88. PMID 12957370 DOI: 10.1016/S0006-8993(03)03170-6  0.401
2002 Smith FL, Javed R, Elzey MJ, Welch SP, Selley D, Sim-Selley L, Dewey WL. Prolonged reversal of morphine tolerance with no reversal of dependence by protein kinase C inhibitors. Brain Research. 958: 28-35. PMID 12468027 DOI: 10.1016/S0006-8993(02)03394-2  0.422
1999 Smith FL, Lohmann AB, Dewey WL. Involvement of phospholipid signal transduction pathways in morphine tolerance in mice. British Journal of Pharmacology. 128: 220-6. PMID 10498855 DOI: 10.1038/sj.bjp.0702771  0.411
1999 Smith FL, Dombrowski DS, Dewey WL. Involvement of intracellular calcium in morphine tolerance in mice. Pharmacology, Biochemistry, and Behavior. 62: 381-8. PMID 9972707 DOI: 10.1016/S0091-3057(98)00168-3  0.306
1997 Welch SP, Smith FL, Dewey WL. Morphine tolerance-induced modulation of [3H]glyburide binding to mouse brain and spinal cord. Drug and Alcohol Dependence. 45: 47-53. PMID 9179506 DOI: 10.1016/S0376-8716(97)01343-4  0.351
1994 McLaughlin CR, Dewey WL. A comparison of the antinociceptive effects of opioid agonists in neonatal and adult rats in phasic and tonic nociceptive tests. Pharmacology, Biochemistry, and Behavior. 49: 1017-23. PMID 7886070 DOI: 10.1016/0091-3057(94)90258-5  0.358
1993 White CW, Ward CR, Dombrowski DS, Dunlow LD, Brase DA, Dewey WL. Effect of intrathecal morphine on the fate of glucose. Comparison with effects of insulin and xanthan gum in mice. Biochemical Pharmacology. 45: 459-64. PMID 8435095 DOI: 10.1016/0006-2952(93)90083-9  0.351
1993 Saxen MA, Welch SP, Dewey WL. The mouse paw withdrawal assay: a method for determining the effect of calcitonin gene-related peptide on cutaneous heat nociceptive latency time. Life Sciences. 53: 397-405. PMID 8336518 DOI: 10.1016/0024-3205(93)90643-H  0.341
1993 Smith FL, Dewey WL. Endogenous dynorphin modulates calcium-mediated antinociception in mice. Pharmacology, Biochemistry, and Behavior. 45: 383-91. PMID 8101006 DOI: 10.1016/0091-3057(93)90255-R  0.303
1991 Brase DA, Ward CR, Bey PS, Dewey WL. Antagonism of the morphine-induced locomotor activation of mice by fructose: comparison with other opiates and sugars, and sugar effects on brain morphine. Life Sciences. 49: 727-34. PMID 1875782 DOI: 10.1016/0024-3205(91)90105-K  0.428
1991 Adams ML, Morris DL, Brase DA, Dewey WL. Stereoselective effect of morphine on antinociception and endogenous opioid peptide levels in plasma but not cerebrospinal fluid of dogs. Life Sciences. 48: 917-24. PMID 1671791 DOI: 10.1016/0024-3205(91)90039-E  0.387
1991 McLaughlin CR, Dewey WL, Fanselow MS. Short- and long-term factors in tolerance to morphine-induced antinociception: Single or multiple mechanisms? Psychobiology. 19: 217-222. DOI: 10.3758/BF03332071  0.335
1990 Brase DA, Singha AK, Estrada U, Lux F, Dewey WL. Hypoglycemia induced by intrathecal opioids in mice: stereospecificity, drug specificity and effect of fasting. The Journal of Pharmacology and Experimental Therapeutics. 253: 899-904. PMID 2359029  0.309
1990 Compton DR, Dewey WL, Martin BR. Cannabis dependence and tolerance production. Advances in Alcohol & Substance Abuse. 9: 129-47. PMID 2165734 DOI: 10.1300/J251V09N01_08  0.462
1989 Tripathi HL, Dewey WL. Comparison of the effects of diisopropylfluorophosphate, sarin, soman, and tabun on toxicity and brain acetylcholinesterase activity in mice. Journal of Toxicology and Environmental Health. 26: 437-46. PMID 2709438 DOI: 10.1080/15287398909531267  0.333
1989 Brase DA, Myer EC, Dewey WL. Possible hyperendorphinergic pathophysiology of the Rett syndrome. Life Sciences. 45: 359-66. PMID 2475733 DOI: 10.1016/0024-3205(89)90620-6  0.332
1988 Lux F, Brase DA, Dewey WL. Antagonism of antinociception in mice by glucose and fructose: comparison of subcutaneous and intrathecal morphine. European Journal of Pharmacology. 146: 337-40. PMID 3371404 DOI: 10.1016/0014-2999(88)90312-3  0.359
1987 Estrada U, Brase DA, Martin BR, Dewey WL. Cardiovascular effects of delta 9- and delta 9(11)-tetrahydrocannabinol and their interaction with epinephrine. Life Sciences. 41: 79-87. PMID 3037218 DOI: 10.1016/0024-3205(87)90559-5  0.503
1987 Young R, Glennon RA, Dewey WL. Effects of pyrazolopyridines and a triazolopyridazine on the pentobarbital discriminative stimulus. Psychopharmacology. 93: 494-7. PMID 2893416 DOI: 10.1007/Bf00207241  0.333
1987 Brase DA, Han YH, Dewey WL. Effects of glucose and diabetes on binding of naloxone and dihydromorphine to opiate receptors in mouse brain. Diabetes. 36: 1173-7. PMID 2820820 DOI: 10.2337/Diab.36.10.1173  0.337
1986 Aceto MD, Bagley RS, Dewey WL, Fu TC, Martin BR. The spinal cord as a major site for the antinociceptive action of nicotine in the rat. Neuropharmacology. 25: 1031-6. PMID 3774124 DOI: 10.1016/0028-3908(86)90198-X  0.449
1986 Aceto MD, Dewey WL, Portoghese PS, Takemori AE. Effects of beta-funaltrexamine (beta-FNA) on morphine dependence in rats and monkeys. European Journal of Pharmacology. 123: 387-93. PMID 3720824 DOI: 10.1016/0014-2999(86)90713-2  0.381
1986 Adams ML, Brase DA, Welch SP, Dewey WL. The role of endogenous peptides in the action of opioid analgesics. Annals of Emergency Medicine. 15: 1030-5. PMID 3526991 DOI: 10.1016/S0196-0644(86)80124-X  0.361
1986 Young R, Glennon RA, Brase DA, Dewey WL. Potencies of diazepam metabolites in rats trained to discriminate diazepam. Life Sciences. 39: 17-20. PMID 3088348 DOI: 10.1016/0024-3205(86)90432-7  0.315
1985 Kachur JF, Rosemond R, Welch S, Bowman ER, Martin BR, Brase DA, Dewey WL. Comparison of the ability of opioid analgesics to increase endogenous opioid-like activity in the cerebrospinal fluid of rabbits. Life Sciences. 37: 2549-55. PMID 4079662 DOI: 10.1016/0024-3205(85)90613-7  0.547
1985 Widman M, Tucker S, Brase DA, Dewey WL. Cholinergic agents: antinociception without morphine type dependence in rats. Life Sciences. 36: 2007-15. PMID 4039782 DOI: 10.1016/0024-3205(85)90450-3  0.349
1985 Jorapur VS, Khalil ZH, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Hashish: synthesis and central nervous system activity of some novel analogues of cannabidiol and oxepin derivatives of delta 9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 28: 783-7. PMID 2989518 DOI: 10.1021/Jm00383A016  0.696
1985 Cobert BJ, Dewey WL, Stewart JK. Effects of branched-chain amino acids on beta-endorphin in the pituitary of the rat. Neuroscience Letters. 58: 339-42. PMID 2931626 DOI: 10.1016/0304-3940(85)90077-1  0.305
1984 Shook JE, Kallman MJ, Dewey WL. The discriminative stimulus properties of the R2 isomer of viminol. Pharmacology, Biochemistry, and Behavior. 20: 59-62. PMID 6546450 DOI: 10.1016/0091-3057(84)90101-1  0.353
1984 Tagashira E, Kachur JF, Carter WH, Dewey WL. Pentazocine-tripelennamine ("T's and Blues") substitution studies in morphine-dependent rodents. The Journal of Pharmacology and Experimental Therapeutics. 231: 97-101. PMID 6541694 DOI: 10.1016/B978-008055232-3.62389-X  0.308
1984 Robertson LR, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Synthesis and pharmacological activity of some 9-substituted delta 8-tetrahydrocannabinol analogues. Journal of Medicinal Chemistry. 27: 550-2. PMID 6323713 DOI: 10.1021/Jm00370A023  0.688
1984 Shook JE, Kallman MJ, Martin BR, Dewey WL. Characterization of the interaction of pentazocine and tripelennamine: drug discrimination and mu-receptor binding assay. Pharmacology, Biochemistry, and Behavior. 21: 877-81. PMID 6097919 DOI: 10.1016/S0091-3057(84)80068-4  0.517
1984 Martin BR, Kallman MJ, Kaempf GF, Harris LS, Dewey WL, Razdan RK. Pharmacological potency of R- and S-3'-hydroxy-delta 9-tetrahydrocannabinol: additional structural requirement for cannabinoid activity. Pharmacology, Biochemistry, and Behavior. 21: 61-5. PMID 6087379 DOI: 10.1016/0091-3057(84)90131-X  0.681
1984 ROBERTSON LR, DUFFLEY RP, RAZDAN RK, MARTIN BR, HARRIS LS, DEWEY WL. ChemInform Abstract: SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF SOME 9-SUBSTITUTED Δ8-TETRAHYDROCANNABINOL (THC) ANALOGS Chemischer Informationsdienst. 15. DOI: 10.1002/CHIN.198438203  0.585
1983 Welch SP, Vocci FJ, Dewey WL. Antinociceptive and lethal effects of intraventricularly administered barium and strontium: antagonism by atropine sulfate or naloxone hydrochlorine. Life Sciences. 33: 359-64. PMID 6877028 DOI: 10.1016/S0024-3205(83)80009-5  0.398
1983 Kiang JG, Dewey WL, Wei ET. Tolerance to morphine bradycardia in the rat. The Journal of Pharmacology and Experimental Therapeutics. 226: 187-91. PMID 6864538  0.312
1983 Dewey WL, Bowman E, Jones D, Kachur J, Rosemond R, Welch S, Martin BR. Pharmachology The appearance of endogenous opiates in cerebrospinal fluid following opiate injection in various animal species Pain. 17: 393. DOI: 10.1016/0304-3959(83)90171-9  0.444
1983 HANDRICK GR, DUFFLEY RP, LAMBERT G, MURPHY JG, DALZELL HC, HOWES JF, RAZDAN RK, MARTIN BR, HARRIS LS, DEWEY WL. ChemInform Abstract: 3′-HYDROXY- AND (.+-.)-3′,11-DIHYDROXY-Δ9-TETRAHYDROCANNABINOL: (THC) BIOLOGICALLY ACTIVE METABOLITES OF Δ9-TETRAHYDROCANNABINOL Chemischer Informationsdienst. 14. DOI: 10.1002/CHIN.198322251  0.568
1982 Dewey WL, Bowman E, Jones D, Kachur J, Rosemond R, Welch S, Martin BR. The appearance of endogenous opiates in cerebrospinal fluid following opiate injection in various animal species. Life Sciences. 31: 1741-3. PMID 7154834 DOI: 10.1016/0024-3205(82)90199-0  0.553
1982 Aceto MD, Dewey WL, Chang JK, Lee NM. Dynorphin-(1-13): effects in nontolerant and morphine-dependent rhesus monkeys. European Journal of Pharmacology. 83: 139-42. PMID 6889974 DOI: 10.1016/0014-2999(82)90299-0  0.39
1982 Handrick GR, Duffley RP, Lambert G, Murphy JG, Dalzell HC, Howes JF, Razdan RK, Martin BR, Harris LS, Dewey WL. 3'-Hydroxy- and (+/-)-3',11-dihydroxy-delta 9-tetrahydrocannabinol: biologically active metabolites of delta 9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 25: 1447-50. PMID 6296389  0.675
1982 Dewey WL, Fu TC, Ohlsson A, Bowman E, Martin BR. Evidence for the release of endogenous opiates by morphine. Nida Research Monograph. 41: 60-6. PMID 6289120  0.422
1982 Ohlsson AE, Fu TC, Jones D, Martin BR, Dewey WL. Distribution of radioactivity in the spinal cord after intracerebroventricular and intravenous injection of radiolabeled opioid peptides in mice. The Journal of Pharmacology and Experimental Therapeutics. 221: 362-7. PMID 6281413  0.399
1982 Snow AE, Tucker SM, Dewey WL. The role of neurotransmitters in stress-induced antinociception (SIA). Pharmacology, Biochemistry, and Behavior. 16: 47-50. PMID 6120525 DOI: 10.1016/0091-3057(82)90011-9  0.339
1981 Pedigo NW, Dewey WL. Comparison of the antinociceptive activity of intraventricularly administered acetylcholine to narcotic antinociception. Neuroscience Letters. 26: 85-90. PMID 7290542 DOI: 10.1016/0304-3959(82)90041-0  0.452
1981 Aceto MD, Harris LS, Dewey WL, May EL. Annual report: dependence studies of new compounds in the rhesus monkey (1980). Nida Research Monograph. 34: 297-326. PMID 6783944  0.565
1981 Johnson KM, Dewey WL, Bloom AS. Adrenalectomy reverses the effects of delta-9-THC on mouse brain 5-hydroxytryptamine turnover. Pharmacology. 23: 223-9. PMID 6275421 DOI: 10.1159/000137553  0.743
1981 Chau TT, Dewey WL. Effects of the intracerebroventricular injection of antinociceptive doses of acetylcholine on the stereospecific binding of 3H-dihydromorphine. Life Sciences. 29: 2149-56. PMID 6275221 DOI: 10.1016/0024-3205(81)90484-7  0.358
1981 Martin BR, Balster RL, Razdan RK, Harris LS, Dewey WL. Behavioral comparisons of the stereoisomers of tetrahydrocannabinols. Life Sciences. 29: 565-74. PMID 6268916 DOI: 10.1016/0024-3205(81)90434-3  0.672
1981 End DW, Carchman RA, Dewey WL. Neurochemical correlates of chlordecone neurotoxicity. Journal of Toxicology and Environmental Health. 8: 707-18. PMID 6175764 DOI: 10.1080/15287398109530107  0.305
1980 Fu TC, Halenda SP, Dewey WL. The effect of hypophysectomy on acupuncture analgesia in the mouse. Brain Research. 202: 33-9. PMID 7427744 DOI: 10.1016/S0006-8993(80)80032-1  0.416
1980 Tripathi HL, Vocci FJ, Dewey WL. Effect of antinociceptive doses of oxotremorine on mouse brain acetylcholine turnover rate. Life Sciences. 27: 2055-62. PMID 7207008 DOI: 10.1016/0024-3205(80)90484-1  0.302
1980 Alozie SO, Martin BR, Harris LS, Dewey WL. 3H-delta 9-Tetrahydrocannabinol, 3H-cannabinol and 3H-cannabidiol: penetration and regional distribution in rat brain. Pharmacology, Biochemistry, and Behavior. 12: 217-21. PMID 6246544 DOI: 10.1016/0091-3057(80)90359-7  0.673
1979 Segreti A, Vocci FJ, Dewey WL. Antagonism of barium chloride lethality by atropine and naloxone analysis by a multivariate logistic model. Toxicology and Applied Pharmacology. 50: 25-30. PMID 494298 DOI: 10.1016/0041-008X(79)90488-5  0.375
1979 Fu TC, Dewey WL. Morphine antinociception: evidence for the release of endogenous substance(s). Life Sciences. 25: 53-60. PMID 481121 DOI: 10.1016/0024-3205(79)90489-2  0.372
1979 Wilson RS, May EL, Dewey WL. Some 9-hydroxycannabinoid-like compounds. Synthesis and evaluation of analgesic and behavioral properties. Journal of Medicinal Chemistry. 22: 886-8. PMID 448688 DOI: 10.1021/Jm00193A027  0.326
1979 Wilson RS, Martin BR, Dewey WL. Some 11-substituted tetrahydrocannabinols. Synthesis and comparison with the potent cannabinoid metabolites 11-hydroxytetrahydrocannabinols. Journal of Medicinal Chemistry. 22: 879-82. PMID 448686 DOI: 10.1021/JM00193A025  0.497
1979 Aceto MD, Martin BR, Uwaydah IM, May EL, Harris LS, Izazola-Conde C, Dewey WL, Bradshaw TJ, Vincek WC. Optically pure (+)-nicotine from (+/-)-nicotine and biological comparisons with (-)-nicotine. Journal of Medicinal Chemistry. 22: 174-7. PMID 423195 DOI: 10.1021/JM00188A009  0.642
1979 Aceto MD, Harris LS, Dewey WL, May EL. Annual report: dependence studies on new compounds in the rhesus monkey (1979). Nida Research Monograph. 27: 330-50. PMID 121356  0.565
1979 Rosecrans JA, Campbell OL, Dewey WL, Harris LS. Discriminative stimulus and neurochemical mechanism of cathinone: a preliminary study. Nida Research Monograph. 27: 328-9. PMID 121355  0.531
1978 Dewey WL, Poddar MK, Johnson KM. The effects of cannabinoids on rat brain synaptosomes. Advances in the Biosciences. 22: 343-9. PMID 756834 DOI: 10.1016/B978-0-08-023759-6.50029-9  0.707
1978 McConnell WR, Dewey WL, Harris LS, Borzelleca JF. A study of the effect of delta 9-tetrahydrocannabinol (delta 9-THC) on mammalian salivary flow. The Journal of Pharmacology and Experimental Therapeutics. 206: 567-73. PMID 702321  0.559
1978 Johnson KM, Dewey WL. Effects of delta9-THC on the synaptosomal uptake of 3H-tryptophan and 3H-choline. Pharmacology. 17: 83-7. PMID 684080 DOI: 10.1159/000136839  0.707
1978 Patrick GA, Dewey WL, Huger FP, Daves ED, Harris LS. Disposition of morphine in chronically infused rats: relationship to antinociception and tolerance. The Journal of Pharmacology and Experimental Therapeutics. 205: 556-62. PMID 660529  0.652
1978 Johnson KM, Dewey WL, Ritter KS, Beckner JS. Cannabinoid effects on plasma corticosterone and uptake of 3H-corticosterone by mouse brain. European Journal of Pharmacology. 47: 303-10. PMID 631183 DOI: 10.1016/0014-2999(78)90238-8  0.695
1978 Lujan M, Chau-Pham TT, Aceto MD, Dewey WL. The effect of sodium ion on antinociception and opiate binding in vivo. Life Sciences. 23: 1431-9. PMID 213670 DOI: 10.1016/0024-3205(78)90124-8  0.407
1978 Chau-Pham TT, King G, Dewey WL. Sodium-induced alterations of opiate effects on the binding of 3H-dihydromorphine to mouse brain homogenates. Life Sciences. 23: 1293-9. PMID 213669 DOI: 10.1016/0024-3205(78)90508-8  0.373
1978 Fraser HF, Kay DC, Yeh SY, Gorodetzky CW, Dewey WL. Possible effects of normetabolites on the subjective and reinforcing characteristics of opioids in animals and man. Drug and Alcohol Dependence. 3: 301-18. PMID 101364 DOI: 10.1016/0376-8716(78)90001-7  0.4
1978 Bloom AS, Dewey WL. A comparison of some pharmacological actions of morphine and delta9-tetrahydrocannabinol in the mouse. Psychopharmacology. 57: 243-8. PMID 97703 DOI: 10.1007/Bf00426745  0.422
1978 Martin BR, Montgomery J, Dewey WL, Harris LS. Alterations in the pharmacokinetics of 3H-delta9-tetrahydrocannabinol in mice by bacterial endotoxin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 6: 282-7. PMID 26549  0.68
1978 Fraser H, Kay D, Gorodetzky C, Yeh S, Dewey W. Evidence for the importance of N-dealkylation in opioid pharmacology Drug and Alcohol Dependence. 3: 1-22. DOI: 10.1016/0376-8716(78)90031-5  0.384
1977 Martin BR, Dewey WL, Harris LS, Beckner JS. 3H-delta9-tetrahydrocannabinol distribution in pregnant dogs and their fetuses. Research Communications in Chemical Pathology and Pharmacology. 17: 457-70. PMID 897339  0.635
1977 Adams MD, Earnhardt JT, Martin BR, Harris LS, Dewey WL, Razdan RK. A cannabinoid with cardiovascular activity but no overt behavioral effects. Experientia. 33: 1204-5. PMID 891878 DOI: 10.1007/Bf01922330  0.678
1977 Ford RD, Balster RL, Dewey WL, Beckner JS. delta 9-THC and 11-OH-delta 9-THC: behavioral effects and relationship to plasma and brain levels. Life Sciences. 20: 1993-2003. PMID 881943 DOI: 10.1016/0024-3205(77)90178-3  0.362
1977 Bloom AS, Dewey WL, Harris LS, Brosius KK. 9-nor-9beta-hydroxyhexahydrocannabinol, a cannabinoid with potent antinociceptive activity: comparisons with morphine. The Journal of Pharmacology and Experimental Therapeutics. 200: 263-70. PMID 839438  0.629
1977 Martin BR, Dewey WL, Aceto MD, Adams MD, Earnhardt JT, Carney JM. A potent antinociceptive cannabinoid which lacks opiate substitution properties in monkeys. Research Communications in Chemical Pathology and Pharmacology. 16: 187-90. PMID 402685  0.441
1977 Martin BR, Dewey WL, Chau-Pham T, Prnage AJ. Interactions of thyrotropin releasing hormone and morphine sulfate in rodents. Life Sciences. 20: 715-22. PMID 402526 DOI: 10.1016/0024-3205(77)90477-5  0.545
1977 Bradley SG, Munson AE, Dewey WL, Harris LS. Enhanced susceptibility of mice to combinations of delta 9-tetrahydrocannabinol and live or killed gram-negative bacteria. Infection and Immunity. 17: 325-9. PMID 330405  0.579
1977 Chau-Pham TT, Dewey WL. A comparative study of the effect of methionine enkephalin upon the stereospecific binding of an opiate agonist and an antagonist in mice and rats. Life Sciences. 21: 1337-42. PMID 200814 DOI: 10.1016/0024-3205(77)90016-9  0.354
1976 Dionne RA, Dewey WL, Joy E. A survey of the teaching of pain control at the predoctoral level. Anesthesia Progress. 23: 152-4. PMID 19598503  0.423
1976 Martin BR, Dewey WL, Harris LS, Beckner JS. 3H-delta9-tetrahydrocannabinol tissue and subcellular distribution in the central nervous system and tissue distribution in peripheral organs of tolerant and nontolerant dogs. The Journal of Pharmacology and Experimental Therapeutics. 196: 128-44. PMID 1246007  0.651
1976 Atkinson ER, Battista SP, Ary IE, Richardson DG, Harris LS, Dewey WL. Derivatives of apomorphine and of other N-substituted norapomorphines. Journal of Pharmaceutical Sciences. 65: 1682-5. PMID 994002 DOI: 10.1002/Jps.2600651129  0.585
1976 Wilson RS, May EL, Martin BR, Dewey WL. 9 Nor 9 hydroxyhexahydrocannabinols. Synthesis, some behavioral and analgesic properties, and comparison with the tetrahydrocannabinols Journal of Medicinal Chemistry. 19: 1165-1167. PMID 978681 DOI: 10.1002/Chin.197652236  0.499
1976 Day AR, Luján M, Dewey WL, Harris LS, Radding JA, Freer RJ. Structure-activity relationships of enkephalins in the stimulated guinea pig ileum. Research Communications in Chemical Pathology and Pharmacology. 14: 597-603. PMID 959662  0.584
1976 Johnson KM, Dewey WL, Harris LS. Some structural requirements for inhibition of high-affinity synaptosomal serotonin uptake by cannabinoids. Molecular Pharmacology. 12: 345-52. PMID 934055  0.551
1976 Dewey WL, Johnson KM, Bloom AS. Interactions of active constituents of marihuana with other drugs in the neuron. Annals of the New York Academy of Sciences. 281: 190-7. PMID 798522 DOI: 10.1111/J.1749-6632.1976.Tb27930.X  0.665
1976 Forbes JE, Dewey WL. The effects of narcotic analgesics and narcotic antagonists on ganglionic transmission in the rat. Life Sciences. 19: 401-7. PMID 183075 DOI: 10.1016/0024-3205(76)90045-X  0.405
1976 Bloom AS, Dewey WL, Harris LS, Brosius KK. The correlation between antinociceptive activity of narcotics and their antagonists as measured in the mouse tail-flick test and increased synthesis of brain catecholamines. The Journal of Pharmacology and Experimental Therapeutics. 198: 33-41. PMID 6793  0.661
1976 Adams MD, Earnhardt JT, Dewey WL, Harris LS. Vasoconstrictor actions of delta8- and delta9-tetrahydrocannabinol in the rat. The Journal of Pharmacology and Experimental Therapeutics. 196: 649-56. PMID 4606  0.61
1976 Pedigo NW, Dewey WL, Harris LS. Pharmacology Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice Pain. 2: 86. DOI: 10.1016/0304-3959(76)90055-5  0.652
1975 Martin BR, Dewey WL, Harris LS, Beckner J. Marihuana-like activity of new synthetic tetrahydrocannabinols. Pharmacology, Biochemistry, and Behavior. 3: 849-53. PMID 1208625 DOI: 10.1016/0091-3057(75)90116-1  0.71
1975 Munson AE, Harris LS, Friedman MA, Dewey WL, Carchman RA. Antineoplastic activity of cannabinoids. Journal of the National Cancer Institute. 55: 597-602. PMID 1159836  0.601
1975 Patrick GA, Dewey WL, Spaulding TC, Harris LS. Relationship of brain morphine levels to analgesic activity in acutely treated mice and rats and in pellet implanted mice. The Journal of Pharmacology and Experimental Therapeutics. 193: 876-83. PMID 1151736  0.647
1975 Pedigo NW, Dewey WL, Harris LS. Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice. The Journal of Pharmacology and Experimental Therapeutics. 193: 845-52. PMID 1151733  0.67
1975 Dewey WL, Cocolas G, Daves E, Harris LS. Stereospecificity of intraventricularly administered acetylmethylcholine antinociception. Life Sciences. 17: 9-10. PMID 1143014 DOI: 10.1016/0024-3205(75)90224-6  0.68
1975 Chipkin RE, Dewey WL, Harris LS, Lowenthal W. Effect of propranolol on antinociceptive and withdrawal characteristics of morphine. Pharmacology, Biochemistry, and Behavior. 3: 843-7. PMID 1800 DOI: 10.1016/0091-3057(75)90115-X  0.683
1975 Martin BR, Dewey WL, Harris LS, Beckner J, Wilson RS, May EL. Marihuana-like activity of new synthetic tetrahydrocannabinols Pharmacology, Biochemistry and Behavior. 3: 849-853. DOI: 10.1016/0091-3057(75)90116-1  0.555
1973 Kosersky DS, Dewey WL, Harris LS. Antipyretic, analgesic and anti-inflammatory effects of delta 9-tetrahydrocannabinol in the rat. European Journal of Pharmacology. 24: 1-7. PMID 4756165 DOI: 10.1016/0014-2999(73)90107-6  0.613
1973 Chau TT, Dewey WL, Harris LS. Mechanism of the synergistic lethality between pentazocine and vasopressin in the rat. The Journal of Pharmacology and Experimental Therapeutics. 186: 288-96. PMID 4719781  0.56
1973 Turk RF, Dewey WL, Harris LS. Excretion of trans- 9 -tetrahydrocannabinol and its metabolites in intact and bile duct-cannulated rats. Journal of Pharmaceutical Sciences. 62: 737-40. PMID 4705677 DOI: 10.1002/Jps.2600620506  0.605
1973 Dewey WL, McMillan DE, Harris LS, Turk RF. Distribution of radioactivity in brain of tolerant and nontolerant pigeons treated with 3 H- 9 -tetrahydrocannabinol. Biochemical Pharmacology. 22: 399-405. PMID 4687135 DOI: 10.1016/0006-2952(73)90420-6  0.593
1973 McMillan DE, Dewey WL, Turk RF, Harris LS, McNeil JH. Blood levels of 3 H- 9 -tetrahydrocannabinol and its metabolites in tolerant and nontolerant pigeons. Biochemical Pharmacology. 22: 383-97. PMID 4687134 DOI: 10.1016/0006-2952(73)90419-X  0.594
1972 Dewey WL, Harris LS, Kennedy JS. Some pharmacological and toxicological effects of 1-trans- 8 and 1-trans- 9 -tetrahydrocannabinol in laboratory rodents. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 196: 133-45. PMID 5059359  0.579
1972 Dewey WL, Jenkins J, O'Rourke T, Harris LS. The effects of chronic administration of trans- 9 -tetrahydrocannabinol on behavior and the cardiovascular system of dogs. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 198: 118-31. PMID 5053234  0.576
1972 Zitko BA, Howes JF, Razdan RK, Dalzell BC, Dalzell HC, Sheehan JC, Pars HG, Dewey WL, Harris LS. Water-soluble derivatives of 1 -tetrahydrocannabinol. Science (New York, N.Y.). 177: 442-4. PMID 5043146 DOI: 10.1126/science.177.4047.442  0.56
1972 Spaulding TC, Ford RD, Dewey WL, McMillan DE, Harris LS. Some pharmacological effects of phenitrone and its interaction with 9 -THC. European Journal of Pharmacology. 19: 310-7. PMID 4640854 DOI: 10.1016/0014-2999(72)90096-9  0.642
1972 ZITKO BA, HOWES JF, RAZDAN RK, DALZELL BC, DALZELL HC, SHEEHAN JC, PARS HG, DEWEY WL, HARRIS LS. ChemInform Abstract: WASSERLOESLICHE DERIVATE VON DELTA(1)-TETRAHYDROCANNABINOL Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/chin.197250288  0.573
1971 McMillan DE, Dewey WL, Harris LS. CHARACTERISTICS OF TETRAHYDROCANNABINOL TOLERANCE Annals of the New York Academy of Sciences. 191: 83-99. DOI: 10.1111/J.1749-6632.1971.Tb13990.X  0.563
1970 Howes JF, Harris LS, Dewey WL. The effect of morphine, nalorphine, naloxone, pentazocine, cyclazocine and oxotremorine on the synthesis and release of acetylcholine by mouse cerebral cortex slices in vitro. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 184: 267-76. PMID 5453231  0.614
1970 Dewey WL, Harris LS, Howes JF, Kennedy JS, Granchelli FE, Pars HG, Razdan RK. Pharmacology of some marijuana constituents and 2 heterocyclic analogues. Nature. 226: 1265-7. PMID 5422606 DOI: 10.1038/2261265A0  0.577
1970 Dewey WL, Harris LS, Howes JF, Nuite JA. The effect of various neurohumoral modulators on the activity of morphine and the narcotic antagonists in the tail-flick and phenylquinone tests. The Journal of Pharmacology and Experimental Therapeutics. 175: 435-42. PMID 4394803  0.638
1970 Dewey WL, Peng TC, Harris LS. The effect of 1-trans-delta 9-tetrahydrocannabinol on the hypothalamo-hypophyseal-adrenal axis of rats. European Journal of Pharmacology. 12: 382-4. PMID 4322071 DOI: 10.1016/0014-2999(70)90094-4  0.597
1969 Howes JF, Harris LS, Dewey WL, Voyda CA. Brain acetylcholine levels and inhibition of the tail-flick reflex in mice. The Journal of Pharmacology and Experimental Therapeutics. 169: 23-8. PMID 5804609  0.595
1969 Dewey WL, Harris LS, Howes JF, Kennedy JS, Nuite JA, Hayhurst V. The effects of narcotic-antagonist analgesics on rat brain cholinesterases. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 182: 471-80. PMID 5371206  0.603
1969 Harris LS, Dewey WL, Howes JF, Kennedy JS, Pars H. Narcotic-antagonist analgesics: interactions with cholinergic systems. The Journal of Pharmacology and Experimental Therapeutics. 169: 17-22. PMID 4389919  0.563
1969 Dewey WL, Snyder JW, Harris LS, Howes JF. The effect of narcotics and narcotic antagonists on the tail-flick response in spinal mice. The Journal of Pharmacy and Pharmacology. 21: 548-50. PMID 4389723 DOI: 10.1111/J.2042-7158.1969.Tb08312.X  0.59
1967 Harris LS, Pierson AK, Dembinski JR, Dewey WL. The pharmacology of (minus)-3-hydroxy-N-cyclopropylmethylmorphinan (cyclorphan). Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 165: 112-26. PMID 4382141  0.539
Low-probability matches (unlikely to be authored by this person)
1986 Welch SP, Cooper CW, Dewey WL. Antinociceptive activity of salmon calcitonin injected intraventricularly in mice: modulation of morphine antinociception. The Journal of Pharmacology and Experimental Therapeutics. 237: 54-8. PMID 3958973  0.298
1984 Tagashira E, Kachur JF, Carter WH, Dewey WL. Potentiation of narcotic-induced antinociception by tripelennamine in morphine-tolerant and drug-naive mice. The Journal of Pharmacology and Experimental Therapeutics. 229: 214-7. PMID 6707938  0.296
2023 Muchhala K, Kang M, Koseli E, Poklis J, Xu Q, Dewey W, Fettweis J, Jimenez N, Akbarali H. The Role of Morphine-Induced Impairment of Intestinal Epithelial Antibacterial Activity in Dysbiosis and its Impact on the Microbiota-Gut-Brain Axis. Research Square. PMID 37503065 DOI: 10.21203/rs.3.rs-3084467/v1  0.295
1983 Snow AE, Dewey WL. A comparison of antinociception induced by foot shock and morphine. The Journal of Pharmacology and Experimental Therapeutics. 227: 42-50. PMID 6312021  0.292
1994 Smith FL, Brase DA, Dombrowski DS, Dewey WL. Endogenous opioids released by suspending mice by the tail selectively enhance spinal mu opioid analgesia. The Journal of Pharmacology and Experimental Therapeutics. 270: 1177-85. PMID 7932169  0.288
1990 Myer EC, Morris DL, Brase DA, Dewey WL, Zimmerman AW. Naltrexone therapy of apnea in children with elevated cerebrospinal fluid beta-endorphin. Annals of Neurology. 27: 75-80. PMID 2137320 DOI: 10.1002/ana.410270112  0.288
1984 Young R, Glennon RA, Dewey WL. Stereoselective stimulus effects of 3-methylflunitrazepam and pentobarbital. Life Sciences. 34: 1977-83. PMID 6328149 DOI: 10.1016/0024-3205(84)90129-2  0.287
1991 Brase DA, Ward CR, Tripathi HL, Dewey WL. An insulin-independent mechanism of intrathecal morphine-induced hypoglycemia in mice: mediation through a central alpha-2 adrenergic pathway. The Journal of Pharmacology and Experimental Therapeutics. 257: 587-94. PMID 1674529  0.286
2022 Huang B, Li M, Klongkumnuankarn P, Mendez RE, Gillespie JC, Stevens DL, Dewey WL, Selley DE, Zhang Y. Rational Design, Chemical Syntheses, and Biological Evaluations of Peripherally Selective Mu Opioid Receptor Ligands as Potential Opioid Induced Constipation Treatment. Journal of Medicinal Chemistry. PMID 35255683 DOI: 10.1021/acs.jmedchem.1c02185  0.284
1981 Fu TC, Dewey WL. A new technique for the in vivo bioassay of opiates and other drugs on mouse spinal cord. European Journal of Pharmacology. 74: 239-42. PMID 7327203 DOI: 10.1016/0014-2999(81)90536-7  0.283
1989 Lux F, Han YH, Brase DA, Dewey WL. Studies on the mechanism of hypoglycemia induced by intrathecal morphine: dissociation from behavioral effects, effects of tolerance and depletion of liver glycogen. The Journal of Pharmacology and Experimental Therapeutics. 249: 688-93. PMID 2732944  0.278
1988 Lux F, Brase DA, Dewey WL. Differential effects of subcutaneous and intrathecal morphine administration on blood glucose in mice: comparison with intracerebroventricular administration. The Journal of Pharmacology and Experimental Therapeutics. 245: 187-94. PMID 3361441  0.277
1993 Natsuki R, Dewey WL. Changes in the levels of several endogenous opioid peptides in dog cerebrospinal fluid following morphine administration. ArukåRu Kenkyå« to Yakubutsu Izon = Japanese Journal of Alcohol Studies & Drug Dependence. 28: 379-93. PMID 8267521  0.274
1978 Day AR, Carney JM, Rosecrans JA, Dewey WL, Freer RJ. Synthesis of two enzyme resistant enkephalin analogs possessing enhanced analgesic activity. Research Communications in Chemical Pathology and Pharmacology. 20: 59-68. PMID 663409  0.273
1979 End DW, Carchman RA, Ameen R, Dewey WL. Inhibition of rat brain mitochondrial calcium transport by chlordecone. Toxicology and Applied Pharmacology. 51: 189-96. PMID 93321 DOI: 10.1016/0041-008X(79)90021-8  0.273
2022 Pagare PP, Li M, Zheng Y, Kulkarni AS, Obeng S, Huang B, Ruiz C, Gillespie JC, Mendez RE, Stevens DL, Poklis JL, Halquist MS, Dewey WL, Selley DE, Zhang Y. Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists. Journal of Medicinal Chemistry. PMID 35255685 DOI: 10.1021/acs.jmedchem.2c00087  0.273
2014 Maguma HT, Datta De D, Bhave S, Dewey WL, Akbarali HI. Specific localization of β-Arrestin2 in myenteric plexus of mouse gastrointestinal tract. Plos One. 9: e103894. PMID 25083714 DOI: 10.1371/Journal.Pone.0103894  0.273
2000 Campbell VC, Dewey WL, Welch SP. Comparison of [(3)H]Glyburide binding with opiate analgesia, tolerance, and dependence in ICR and Swiss-Webster mice. The Journal of Pharmacology and Experimental Therapeutics. 295: 1112-9. PMID 11082447  0.271
2022 Sierra S, Muchhala KH, Jessup DK, Contreras KM, Shah UH, Stevens DL, Jimenez J, Cuno Lavilla XK, de la Fuente Revenga M, Lippold KM, Shen S, Poklis JL, Qiao LY, Dewey WL, Akbarali HI, et al. Sex-specific role for serotonin 5-HT receptor in modulation of opioid-induced antinociception and reward in mice. Neuropharmacology. 108988. PMID 35183539 DOI: 10.1016/j.neuropharm.2022.108988  0.27
1976 Razdan RK, Howes JF, Uliss DB, Dalzell HC, Handrick GR, Dewey WL. (-)-8beta-hydroxymethyl-delta1-tetrahydrocannabinol: a novel physiologically active analog of delta1-tetrahydrocannabinol. Experientia. 32: 416-7. PMID 1269636 DOI: 10.1007/Bf01920767  0.269
1990 Welch SP, Dewey WL. The activity of several peptide fragments of parathyroid hormone, alone and in combination with salmon calcitonin and morphine, in antinociceptive tests in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 252: 140-6. PMID 2299586  0.267
1979 Vocci FJ, Karbowski MJ, Dewey WL. Apparent in vivo acetylcholine turnover rate in whole mouse brain: evidence for a two compartment model by two independent kinetic analyses. Journal of Neurochemistry. 32: 1417-22. PMID 438813 DOI: 10.1111/J.1471-4159.1979.Tb11079.X  0.266
2013 Smith TH, Grider JR, Dewey WL, Akbarali HI. Correction: Morphine decreases enteric neuron excitability via inhibition of sodium channels (PLoS ONE) Plos One. 8. DOI: 10.1371/Annotation/C2D0D839-3Fea-4Dfd-Ad78-4E4Fb1271B20  0.266
1973 Dewey WL, Harris LS. Antagonistic activity of morphine and other narcotics in the mouse locomotor activity test Pharmacologist. 15: 65.  0.263
1992 Myer EC, Tripathi HL, Brase DA, Dewey WL. Elevated CSF beta-endorphin immunoreactivity in Rett's syndrome: report of 158 cases and comparison with leukemic children. Neurology. 42: 357-60. PMID 1736165 DOI: 10.1212/WNL.42.2.357  0.262
1990 Zimmerman RS, Hayes RL, Morris DL, Lyeth BG, Dewey WL, Young HF. Beta-endorphin in cerebrospinal fluid and serum after severe head injury. Neurosurgery. 26: 764-70. PMID 2352593 DOI: 10.1097/00006123-199005000-00005  0.261
2021 Muchhala KH, Jacob JC, Dewey WL, Akbarali HI. Role of β-arrestin-2 in short- and long-term opioid tolerance in the dorsal root ganglia. European Journal of Pharmacology. 899: 174007. PMID 33705801 DOI: 10.1016/j.ejphar.2021.174007  0.26
2014 Ngwainmbi J, De DD, Smith TH, El-Hage N, Fitting S, Kang M, Dewey WL, Hauser KF, Akbarali HI. Effects of HIV-1 Tat on enteric neuropathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14243-51. PMID 25339738 DOI: 10.1523/Jneurosci.2283-14.2014  0.258
1980 Vocci FJ, Welch SP, Dewey WL. Differential effects of divalent cations, cation chelators and an ionophore (A23187) on morphine and dibutyryl guanosine 3': 5'-cyclic monophosphate antinociception. The Journal of Pharmacology and Experimental Therapeutics. 214: 463-6. PMID 6249907  0.258
2015 Fitting S, Ngwainmbi J, Kang M, Khan FA, Stevens DL, Dewey WL, Knapp PE, Hauser KF, Akbarali HI. Sensitization of enteric neurons to morphine by HIV-1 Tat protein. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 27: 468-80. PMID 25703354 DOI: 10.1111/Nmo.12514  0.257
2022 Ma H, Pagare PP, Li M, Neel LT, Mendez RE, Gillespie JC, Stevens DL, Dewey WL, Selley DE, Zhang Y. Structural Alterations of the "Address" Moiety of NAN Leading to the Discovery of a Novel Opioid Receptor Modulator with Reduced hERG Toxicity. Journal of Medicinal Chemistry. PMID 36538027 DOI: 10.1021/acs.jmedchem.2c01499  0.251
2018 Poklis JL, Gonek MM, Wolf CE, Akbarali HI, Dewey WL. Analysis of carbenoxolone by ultra-performance liquid chromatography tandem mass spectrometry in mouse brain and blood after systemic administration. Biomedical Chromatography : Bmc. e4465. PMID 30548295 DOI: 10.1002/Bmc.4465  0.25
1977 Vocci F, Petty S, Harris LS, Dewey WL. Antinociceptive activity of cyclic GMP and other guanosine nucleotides Pharmacologist. 19.  0.248
2023 Li M, Pagare PP, Ma H, St Onge CM, Mendez RE, Gillespie JC, Stevens DL, Dewey WL, Selley DE, Zhang Y. Molecular Pharmacology Profiling of Phenylfentanil and Its Analogues to Understand the Putative Involvement of an Adrenergic Mechanism in Fentanyl-Induced Respiratory Depression. Journal of Medicinal Chemistry. PMID 38156970 DOI: 10.1021/acs.jmedchem.3c01801  0.248
2007 Carroll FI, Kotturi SV, Navarro HA, Mascarella SW, Gilmour BP, Smith FL, Gabra BH, Dewey WL. Synthesis and pharmacological evaluation of phenylethynyl[1,2,4]methyltriazines as analogues of 3-methyl-6-(phenylethynyl)pyridine. Journal of Medicinal Chemistry. 50: 3388-91. PMID 17569516 DOI: 10.1021/jm070078r  0.247
2022 Li M, Stevens DL, Arriaga M, Townsend EA, Mendez RE, Blajkevch NA, Selley DE, Banks ML, Negus SS, Dewey WL, Zhang Y. Characterization of a Potential KOR/DOR Dual Agonist with No Apparent Abuse Liability via a Complementary Structure-Activity Relationship Study on Nalfurafine Analogues. Acs Chemical Neuroscience. PMID 36449691 DOI: 10.1021/acschemneuro.2c00526  0.246
1982 Chau TT, Izazola-Conde C, Dewey WL. Evidence for the existence of peptide and nonpeptide morphine-like materials in mouse brain: effect of an analgesic intracerebroventricular dose of acetylcholine on their levels. The Journal of Pharmacology and Experimental Therapeutics. 222: 612-6. PMID 7108767 DOI: 10.1016/0304-3959(83)90218-X  0.246
2016 Guedia J, Brun P, Bhave S, Fitting S, Kang M, Dewey WL, Hauser KF, Akbarali HI. HIV-1 Tat exacerbates lipopolysaccharide-induced cytokine release via TLR4 signaling in the enteric nervous system. Scientific Reports. 6: 31203. PMID 27491828 DOI: 10.1038/Srep31203  0.245
1984 Tagashira E, Kachur JF, Carter WH, Dewey WL. Potentiation of pentazocine-induced lethality by tripelennamine in drug native and morphine tolerant mice Federation Proceedings. 43: no. 2697.  0.244
1991 Tripathi HL, Eastman NW, Brase DA, Dewey WL. Effects of diving experience on submersion-induced increases in plasma levels of beta-endorphin in scuba divers. Neuropeptides. 18: 223-7. PMID 2052144 DOI: 10.1016/0143-4179(91)90151-8  0.243
2006 Dalton GD, Dewey WL. Protein kinase inhibitor peptide (PKI): a family of endogenous neuropeptides that modulate neuronal cAMP-dependent protein kinase function. Neuropeptides. 40: 23-34. PMID 16442618 DOI: 10.1016/j.npep.2005.10.002  0.238
2011 Dewey W. Naloxone Xpharm: the Comprehensive Pharmacology Reference. 1-6. DOI: 10.1016/B978-008055232-3.62239-1  0.238
1991 Tripathi HL, Eastman NW, Olson KG, Brase DA, Dewey WL. Effects of hyperbaric simulation of scuba diving pressure on plasma beta-endorphin. Pharmacology, Biochemistry, and Behavior. 38: 219-21. PMID 2017449 DOI: 10.1016/0091-3057(91)90615-9  0.236
1976 Wilcox GL, Dewey WL. Morphine analgesia in spinal mice and rats: cholinergic mechanisms Pharmacologist. 18.  0.234
1970 Cocolas GH, Robinson EC, Dewey WL. A comparison of some stereochemical requirements of the acetylcholinesterase and muscarinic receptor areas. Journal of Medicinal Chemistry. 13: 299-301. PMID 5418506 DOI: 10.1021/Jm00296A034  0.234
1993 Pierce EF, Eastman NW, Tripathi HL, Olson KG, Dewey WL. Beta-endorphin response to endurance exercise: relationship to exercise dependence. Perceptual and Motor Skills. 77: 767-70. PMID 8284151 DOI: 10.2466/pms.1993.77.3.767  0.231
2013 Hawkins EG, Dewey WL, Anitha M, Srinivasan S, Grider JR, Akbarali HI. Electrophysiological characteristics of enteric neurons isolated from the immortomouse. Digestive Diseases and Sciences. 58: 1516-27. PMID 23371009 DOI: 10.1007/S10620-013-2557-5  0.231
1987 Adams ML, Eastman NW, Tobin RP, Morris DL, Dewey WL. Increased plasma beta-endorphin immunoreactivity in scuba divers after submersion. Medicine and Science in Sports and Exercise. 19: 87-90. PMID 3574054 DOI: 10.1249/00005768-198704000-00004  0.227
2008 Zhang F, Jin S, Yi F, Xia M, Dewey WL, Li PL. Local production of O2- by NAD(P)H oxidase in the sarcoplasmic reticulum of coronary arterial myocytes: cADPR-mediated Ca2+ regulation. Cellular Signalling. 20: 637-44. PMID 18207366 DOI: 10.1016/J.Cellsig.2007.11.013  0.226
1986 Welch SP, Dewey WL. A characterization of the antinociception produced by intracerebroventricular injection of 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate in mice. The Journal of Pharmacology and Experimental Therapeutics. 239: 320-6. PMID 3095536  0.226
1994 Pierce EF, Eastman NW, McGowan RW, Tripathi H, Dewey WL, Olson KG. Resistance exercise decreases beta-endorphin immunoreactivity. British Journal of Sports Medicine. 28: 164-6. PMID 8000813 DOI: 10.1136/Bjsm.28.3.164  0.224
1993 Smith FL, Welch SP, Dombrowski DS, Dewey WL. The role of endogenous opioids as mediators of the hypothermic effects of intrathecally administered calcium and calcitonin gene-related peptide in mice. The Journal of Pharmacology and Experimental Therapeutics. 266: 1407-15. PMID 8371146  0.224
2013 Smith TH, Ngwainmbi J, Grider JR, Dewey WL, Akbarali HI. An in-vitro preparation of isolated enteric neurons and glia from the myenteric plexus of the adult mouse. Journal of Visualized Experiments : Jove. PMID 23962959 DOI: 10.3791/50688  0.223
2011 Dewey W. Buprenorphine Xpharm: the Comprehensive Pharmacology Reference. 1-8. DOI: 10.1016/B978-008055232-3.61353-4  0.221
1986 Dewey WL. Cannabinoid pharmacology. Pharmacological Reviews. 38: 151-78. PMID 3529128  0.22
1973 Dewey WL. The pharmacology of pentazocine. International Anesthesiology Clinics. 11: 139-53. PMID 4588339  0.219
1984 Kachur JF, Dewey WL. A possible role for a cholecystokinin-like substance in the manifestation of naloxone-induced contractions of the guinea pig ileum following chronic exposure to morphine Federation Proceedings. 43: No. 3806.  0.219
1985 Tagashira E, Dewey WL. Pharmacological effects of T's and blues on narcotic-induced antinociception and physical dependence on morphine Journal of Pharmacobio-Dynamics. 8: S152.  0.219
1989 Welch SP, Singha AK, Dewey WL. The antinociception produced by intrathecal morphine, calcium, A23187, U50,488H, [D-Ala2, N-Me-Phe4, Gly-ol]enkephalin and [D-Pen2, D-Pen5]enkephalin after intrathecal administration of calcitonin gene-related peptide in mice. The Journal of Pharmacology and Experimental Therapeutics. 251: 1-8. PMID 2552070  0.218
2016 Xu X, Zhang A, Halquist MS, Yuan X, Henderson SC, Dewey WL, Li PL, Li N, Zhang F. Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXRα signalling pathway in oxLDL-loaded macrophages. Journal of Cellular and Molecular Medicine. PMID 27629819 DOI: 10.1111/Jcmm.12970  0.218
1983 Aceto MD, Dewey WL, Loh HH, Lee NM. Investigation of the opiate dependence liability of dynorphin fragments and α-neo-endorphin in morphine-dependent rhesus monkeys Federation Proceedings. 42: No. 2122.  0.217
1993 Pierce EF, Eastman NW, Tripathi HT, Olson KG, Dewey WL. Plasma beta-endorphin immunoreactivity: response to resistance exercise. Journal of Sports Sciences. 11: 499-52. PMID 8114174 DOI: 10.1080/02640419308730019  0.214
1987 Myer EC, Morris DL, Adams ML, Brase DA, Dewey WL. Increased cerebrospinal fluid beta-endorphin immunoreactivity in infants with apnea and in siblings of victims of sudden infant death syndrome. The Journal of Pediatrics. 111: 660-6. PMID 2959762 DOI: 10.1016/S0022-3476(87)80239-1  0.214
2022 Muchhala KH, Koseli E, Gade AR, Woods K, Minai S, Kang M, McQuiston AR, Dewey WL, Akbarali HI. Chronic Morphine Induces IL-18 in Ileum Myenteric Plexus Neurons Through Mu-opioid Receptor Activation in Cholinergic and VIPergic Neurons. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 35106734 DOI: 10.1007/s11481-021-10050-3  0.213
1986 Shook JE, Dewey WL. Morphine dependence and diabetes. I. The development of morphine dependence in streptozotocin-diabetic rats and spontaneously diabetic C57BL/KsJ mice. The Journal of Pharmacology and Experimental Therapeutics. 237: 841-7. PMID 3712281  0.213
2016 Xu X, Yuan X, Li N, Dewey WL, Li PL, Zhang F. Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38(-/-) mice. Journal of Cellular and Molecular Medicine. PMID 26818887 DOI: 10.1111/Jcmm.12788  0.212
1995 Dewey WL. Bad manners, not good. Nature. 376: 545. PMID 7637793 DOI: 10.1038/376545a0  0.21
1993 Calabrese VP, Gruemer HD, Tripathi HL, Dewey W, Fortner CA, DeLorenzo RJ. Serum cortisol and cerebrospinal fluid beta-endorphins in status epilepticus. Their possible relation to prognosis. Archives of Neurology. 50: 689-93. PMID 8323469 DOI: 10.1001/archneur.1993.00540070009006  0.208
2021 Muchhala KH, Jacob JC, Kang M, Dewey WL, Akbarali HI. The Guts of the Opioid Crisis. Physiology (Bethesda, Md.). 36: 315-323. PMID 34431418 DOI: 10.1152/physiol.00014.2021  0.207
1987 Tripathi HL, Vocci FJ, Brase DA, Dewey WL. Effects of cannabinoids on levels of acetylcholine and choline and on turnover rate of acetylcholine in various regions of the mouse brain. Alcohol and Drug Research. 7: 525-32. PMID 3620017  0.206
1978 Bloom AS, Johnson KM, Dewey WL. The effects of cannabinoids on body temperature and brain catecholamine synthesis. Research Communications in Chemical Pathology and Pharmacology. 20: 51-7. PMID 663408  0.203
1993 McLaughlin CR, Hull JG, Edwards WH, Cramer CP, Dewey WL. Neonatal pain: a comprehensive survey of attitudes and practices. Journal of Pain and Symptom Management. 8: 7-16. PMID 8482895 DOI: 10.1016/0885-3924(93)90114-B  0.203
1981 Simon GS, Borzelleca J, Dewey WL. Narcotics and diabetes. II. Streptozotocin-induced diabetes selectively alters the potency of certain narcotic analgesics. Mechanism of diabetes: morphine interaction. The Journal of Pharmacology and Experimental Therapeutics. 218: 324-9. PMID 6114167  0.202
1994 Pierce EF, Eastman NW, Dewey WL, Ward C. 210 EFFECTS OF TRAINING SPECIFICITY ON THE B-ENDORPHIN RESPONSE TO EXERCISE Medicine & Science in Sports & Exercise. 26: S37. DOI: 10.1249/00005768-199405001-00211  0.201
1993 Smith FL, Stevens DL, Dewey WL. Evidence that intracerebroventricular (I.C.V.) calcium stimulates spinal dynorphin release to inhibit morphine analgesia in mice Nida Research Monograph Series. 412.  0.201
1981 Simon GS, Dewey WL. Narcotics and diabetes. I. The effects of streptozotocin-induced diabetes on the antinociceptive potency of morphine. The Journal of Pharmacology and Experimental Therapeutics. 218: 318-23. PMID 7019415  0.2
1986 Dewey WL, Adams M, Morris D, Meyer E. Role of endogenous peptides in the action of narcotics Annals of Emergency Medicine. 15: 92. DOI: 10.1016/S0196-0644(86)80504-2  0.2
1977 Johnson KM, Dewey WL. Cannabinoid induced elevations in plasma endogenous corticosterone levels correlate with increased whole brain uptake of 3H-corticosterone in adrenalectomized mice Pharmacologist. 19.  0.199
1980 Fraser HF, Gorodetzky CW, Kay DC, Yeh SY, Dewey WL. Possible influence of opioid normetabolites on the onset, magnitude and quality of the opioid abstinence syndrome Drug and Alcohol Dependence. 5: 255-272. PMID 6989579 DOI: 10.1016/0376-8716(80)90002-2  0.198
1980 Fu TC, Dewey WL. Differential effects of the spinal subarachnoid infusion of morphine and an enzyme-resistant enkephalin in mice Pharmacologist. 22: 416.  0.197
1988 Welch SP, Cooper CW, Dewey WL. An investigation of the antinociceptive activity of calcitonin gene-related peptide alone and in combination with morphine: correlation to 45Ca++ uptake by synaptosomes. The Journal of Pharmacology and Experimental Therapeutics. 244: 28-33. PMID 3257266  0.196
1986 Shook JE, Kachur JF, Brase DA, Dewey WL. Morphine dependence and diabetes. II. Alterations of normorphine potency in the guinea-pig ileum and mouse vas deferens and of ileal morphine dependence by changes in glucose concentration. The Journal of Pharmacology and Experimental Therapeutics. 237: 848-52. PMID 3712282  0.195
1988 Lux F, Welch SP, Brase DA, Dewey WL. Interaction of morphine with intrathecally administered calcium and calcium antagonists: evidence for supraspinal endogenous opioid mediation of intrathecal calcium-induced antinociception in mice. The Journal of Pharmacology and Experimental Therapeutics. 246: 500-7. PMID 3136242  0.192
1983 Tagashira E, Kachur JF, Dewey WL. Cross-physical dependence of combinations of pentazocine and tripelennamine with morphine Federation Proceedings. 42: No. 5133.  0.192
1976 Pedigo NW, Dewey WL, Hobson RJ. Drug alteration of intraventricular administered acetylcholine (Ivt ACh) induced antinociception in mice Federation Proceedings. 35.  0.192
1997 Pierce EF, Dewey WL, Ward C, Fleming D. ??-ENDORPHIN RESPONSE TO EXERCISE AND RECOVERY IN TRAINED DISTANCE RUNNERS 1141 Medicine &Amp Science in Sports &Amp Exercise. 29: 200. DOI: 10.1097/00005768-199705001-01139  0.186
1981 End DW, Carchman RA, Dewey WL. Interactions of narcotics with synaptosomal calcium transport. Biochemical Pharmacology. 30: 674-6. PMID 7271907 DOI: 10.1016/0006-2952(81)90147-7  0.185
1975 Spaulding TC, Dewey WL. Some effects of the behaviorally active drug, phenitrone, a purported hashish and LSD antagonist, on brain noradrenergic and serotonergic systems. Research Communications in Chemical Pathology and Pharmacology. 11: 503-6. PMID 1153889  0.185
1990 Brase DA, Tripathi HL, Dewey WL. Intrathecal morphine and insulin cause hypoglycemia in mice by different mechanisms. Nida Research Monograph. 105: 549-50. PMID 1876115  0.184
1976 Johnson KM, Dewey WL, Ho BT. In vitro alteration of the subcellular distribution of 3H-reserpine in the rat forebrain by delta 9-tetrahydrocannabinol. Research Communications in Chemical Pathology and Pharmacology. 15: 655-71. PMID 1005913  0.183
1968 Dewey WL, Malone MH. Pharmacologic and toxicologic evaluation of 2-(N-tetradecyl-N-ethylamino)-2-methyl-1,3-propanediol hydrochloride, an inhibitor of intestinal absorption. Toxicology and Applied Pharmacology. 12: 115-31. PMID 5660805 DOI: 10.1016/0041-008X(68)90181-6  0.181
2009 Dewey WL. Billy R Martin Neuropsychopharmacology. 34: 2779-2779. DOI: 10.1038/npp.2008.203  0.181
1978 Vocci FJ, Petty SK, Dewey WL. Antinociceptive action of the butyryl derivatives of cyclic guanosine 3':5'-monophosphate. The Journal of Pharmacology and Experimental Therapeutics. 207: 892-8. PMID 215745  0.18
1980 Snow AE, Dewey WL. Stress-induced antinociception (SIA): Antagonism by (+)- and (-)-naloxone and yohimbine and effects on opiate binding in brain regions Pharmacologist. 22: No.800.  0.179
1981 Lamb RG, Dewey WL. Effect of morphine exposure on mouse liver triglyceride formation. The Journal of Pharmacology and Experimental Therapeutics. 216: 496-9. PMID 6259321  0.174
1978 Johnson KM, Dewey WL. The effect of delta9-tetrahydrocannabinol on the conversion of [3H]trypotphan to 5-[3H] hydroxytryptamine in the mouse brain. The Journal of Pharmacology and Experimental Therapeutics. 207: 140-50. PMID 702335  0.173
1978 Widman M, Rosin D, Dewey WL. Effects of divalent cations, lanthanum, cation chelators and an ionophore on acetylcholine antinociception. The Journal of Pharmacology and Experimental Therapeutics. 205: 311-8. PMID 347052  0.172
1984 Shook JE, Dewey WL. Effect of blood glucose on the development of morphine dependence Federation Proceedings. 43: no. 2671.  0.169
1981 Dewey WL. Background on animal testing in the drug delivery systems program. Nida Research Monograph. 28: 69-76. PMID 6791014  0.168
1985 Bowman ER, Tripathi HL, Dewey WL. Effects of DFP, soman and sarin on catecholamine and serotonin levels in selected brain regions of mice Federation Proceedings. 44: No. 580.  0.168
1986 Shook JE, Dewey WL, Burks TF. The central and peripheral effects of delta-9-tetrahydrocannabinol on gastrointestinal transit in mice. Nida Research Monograph. 67: 222-7. PMID 3018573  0.167
1989 Welch SP, Olson KG, Stevens DL, Dewey WL. Modulation of synaptosomal free intracellular calcium in naive and morphine-tolerant mice: correlation of calcium modulation in vitro and in vivo to tolerance development. Nida Research Monograph. 95: 552-3. PMID 2561856  0.163
1992 Smith FL, Dewey WL. Evidence that endogenous opioids mediate the antinociceptive effects of intrathecally administered calcium in mice. The Journal of Pharmacology and Experimental Therapeutics. 262: 995-1003. PMID 1326632  0.16
2022 Hill R, Conibear A, Dewey W, Kelly E, Henderson G. Role of Acetaldehyde in Ethanol Reversal of Tolerance to Morphine-Induced Respiratory Depression in Mice. Advances in Drug and Alcohol Research. 1. PMID 35909497 DOI: 10.3389/adar.2021.10143  0.157
1990 Doyle SA, Burstein SH, Dewey WL, Welch SP. Further studies on the antinociceptive effects of delta 6-THC-7-oic acid. Agents and Actions. 31: 157-63. PMID 2178317 DOI: 10.1007/BF02003237  0.156
1982 Shook JE, Kallman MJ, Dewey WL. Discriminative stimulus properties of the R2 isomer of viminol: Generalization to the morphine cue in rats Federation Proceedings. 41: 6028.  0.155
1974 Spaulding TC, Dewey WL. The effects of phenitrone, a reported hashish antagonist, on the overt behavior of cats. Research Communications in Chemical Pathology and Pharmacology. 7: 347-52. PMID 4818377  0.153
1979 Aceto MD, Dewey WL, Harris LS. Analgesic properties and dependence liability of clonidine Federation Proceedings. 38: No.3286.  0.148
1992 Welch SP, Stevens DL, Dewey WL. A proposed mechanism of action for the antinociceptive effect of intrathecally administered calcium in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 260: 117-27. PMID 1346158  0.147
1976 Johnson KM, Ho BT, Dewey WL. Effects of delta9-tetrahydrocannabinol on neurotransmitter accumulation and release mechanisms in rat forebrain synaptosomes. Life Sciences. 19: 347-56. PMID 957874 DOI: 10.1016/0024-3205(76)90038-2  0.141
1971 Cocolas GH, Robinson EC, Dewey WL, Spaulding TC. Preparation and activity of -substituted acetylcholine iodides. Journal of Pharmaceutical Sciences. 60: 1749-52. PMID 5133939  0.14
1980 Poddar MK, Dewey WL. Effects of cannabinoids on catecholamine uptake and release in hypothalamic and striatal synaptosomes. The Journal of Pharmacology and Experimental Therapeutics. 214: 63-7. PMID 7391971  0.14
1981 Fu TC, Dewey WL. Comparative antinociceptive potency of endorphins infused into the mouse lumbar subarachnoid space Federation Proceedings. 40: 407.  0.139
1985 Tripathi HL, Szakal AR, Dewey WL. Effects of diisopropylfluorophosphate (DFP) on behavior and cholinergic systems in mouse brain Federation Proceedings. 44: No. 581.  0.137
1976 WILSON RS, MAY EL, MARTIN BR, DEWEY WL. ChemInform Abstract: 9-NOR-9-HYDROXYHEXAHYDROCANNABINOLS. SYNTHESIS, SOME BEHAVIORAL AND ANALGESIC PROPERTIES, AND COMPARISON WITH THE TETRAHYDROCANNABINOLS Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/chin.197652236  0.133
1985 Welch SP, Dewey WL. Characterization of the antinociception produced by intracerebroventricular TMB-8 (8-[N,N-diethylamino]octyl-3,4,5-trimethoxybenzoate) in mice Federation Proceedings. 44: No. 6659.  0.132
2010 HUDKINS RL, KACHUR JF, DEWEY WL, DEHAVEN-HUDKINS DL, STUBBINS JF. ChemInform Abstract: Antimuscarinic Activity of a Novel Indan Analogue of Aprophen and Caramiphen. Cheminform. 23: no-no. DOI: 10.1002/chin.199247160  0.131
1985 Cobert BJ, Dewey WL, Stewart JK. Failure of branched-chain amino acids to affect synaptosomal uptake of norepinephrine and dopamine. Research Communications in Chemical Pathology and Pharmacology. 50: 455-8. PMID 4081328  0.131
1976 Carrano RA, Dewey WL, Matthews RJ, Frawley JP. Some pharmacologic aspects of indoprofen - a new analgesic Federation Proceedings. 35.  0.129
1979 Tripathi HL, Vocci FJ, Dewey WL. Effect of cannabinoids on cholinergic systems in various regions of the mouse brain Federation Proceedings. 38: No. 1915.  0.128
1982 Young R, Dewey WL. Differentiation of the behavioral response produced by barbiturates and benzodiazepines by the benzodiazepine antagonist RO 15-1788 Psychopharmacology. 76: No. 50.  0.123
1979 Simon GS, Dewey WL. Blood glucose levels and narcotic activity in mice Federation Proceedings. 38: No. 2707.  0.115
1978 Vocci FJ, Martin BR, Petty S, Dewey WL. Effect of acute and subchronic chloroform exposure on cholinergic parameters in mouse brain Toxicology and Applied Pharmacology. 45.  0.112
1984 Aceto MD, Dewey WL, Portoghese PC, Takemori AE. β-Funaltrexamine (β-FNA) and morphine dependence Federation Proceedings. 43: no. 2668.  0.103
1973 Dewey WL, Tucker LS, Prange A. Some behavioral and toxicological effects of amyl nitrite. Research Communications in Chemical Pathology and Pharmacology. 5: 889-92. PMID 4701280  0.101
1979 End DW, Carchman RA, Dewey WL. Disruption of rat brain synaptosomal membranes by the neurotoxic insecticide kepone Federation Proceedings. 38: No. 3238.  0.101
1975 Johnson KM, Dewey WL. Structure activity relationships of the cannabinoids in blocking synaptosomal serotonin uptake Pharmacologist. 17: 039.  0.1
1980 Snow AE, Tucker SM, Dewey WL. Effect of spinalectomy and d- and l-isomers of pentazocine and cyclazocine on stress-induced-antinociception Federation Proceedings. 39: 3049.  0.098
1973 Dewey WL. Narcotic-antagonist assay procedures in dogs. Advances in Biochemical Psychopharmacology. 8: 263-72. PMID 4794991  0.096
2008 Jia SJ, Jin S, Zhang F, Yi F, Dewey WL, Li PL. Formation and function of ceramide-enriched membrane platforms with CD38 during M1-receptor stimulation in bovine coronary arterial myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1743-52. PMID 18723763 DOI: 10.1152/Ajpheart.00617.2008  0.091
1981 Fu TC, Welch S, Dewey WL. Comparison of antinociceptive potency of various peptides at the supraspinal and the lumbar spinal (L1) levels in the mouse Pharmacologist. 23: no. 491.  0.081
1970 COCOLAS GH, ROBINSON EC, DEWEY WL. ChemInform Abstract: VERGLEICH EINIGER STEREOCHEMISCHER ERFORDERNISSE VON ACETYLCHOLINESTERASE- UND MUSCARIN-REZEPTOR-BEREICHEN Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/CHIN.197024373  0.081
1984 Dewey WL. Various factors which affect the rate of development of tolerance and physical dependence to abused drugs. Nida Research Monograph. 54: 39-49. PMID 6442762  0.079
1992 Welch SL, Smith F, Saxen M, Dewey WL. Effects of endogenous calcium regulating peptides on opiate actions. Nida Research Monograph. 119: 39-43. PMID 1435980  0.074
1983 Poddar MK, Dewey WL. Kepone induced changes in the synaptosomal uptake and release of dopamine in corpus striatum and norepinephrine in hypothalamus Ircs Medical Science. 11: 632-633.  0.072
1987 Phillips B, Cooper KR, Newsome HH, Dewey WL. Effect of sleep loss on beta-endorphin activity, epinephrine levels, and ventilatory responsiveness. Southern Medical Journal. 80: 16-20. PMID 2948280  0.067
2002 Jain M, Arvanitis C, Chu K, Dewey W, Leonhardt E, Trinh M, Sundberg CD, Bishop JM, Felsher DW. Sustained loss of a neoplastic phenotype by brief inactivation of MYC. Science (New York, N.Y.). 297: 102-4. PMID 12098700 DOI: 10.1126/Science.1071489  0.063
1979 Carchman RA, End DW, Dewey WL, Warner W. Marihuana and opiate interactions with hormonal induced systems in cell culture. Progress in Clinical and Biological Research. 27: 237-52. PMID 424432  0.063
1989 Dewey WL. Testing for abuse liability of drugs in humans: Foreward Nida Research Monograph Series. xi.  0.062
1973 Dewey WL. Behavioral procedures: an overview. Advances in Biochemical Psychopharmacology. 8: 415-6. PMID 4794874  0.057
1972 COCOLAS GH, ROBINSON EC, DEWEY WL, SPAULDING TC. ChemInform Abstract: DARST. UND AKTIVITAET VON BETA-SUBSTITUIERTEN ACETYLCHOLINJODIDEN Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/CHIN.197228215  0.054
1990 Welch SP, Stevens DL, Dewey WL. Differential effects of calcitonin gene-related peptide in tests utilizing thermal versus nociceptive stimuli. Nida Research Monograph. 105: 401. PMID 1876052  0.053
2021 Gustafson LL, Arzul I, Burge CA, Carnegie RB, Caceres-Martinez J, Creekmore L, Dewey W, Elston R, Friedman CS, Hick P, Hudson K, Lupo C, Rheault R, Spiegel K, Vásquez-Yeomans R. Optimizing surveillance for early disease detection: Expert guidance for Ostreid herpesvirus surveillance design and system sensitivity calculation. Preventive Veterinary Medicine. 194: 105419. PMID 34274864 DOI: 10.1016/j.prevetmed.2021.105419  0.044
2019 Parry I, Richard R, Aden JK, Yelvington M, Ware L, Dewey W, Jacobson K, Caffrey J, Sen S. Goniometric measurement of burn scar contracture: a paradigm shift challenging the standard. AUTHORS. Journal of Burn Care & Research : Official Publication of the American Burn Association. PMID 30919903 DOI: 10.1093/jbcr/irz038  0.043
1847 Jervis JB, Allen H, Wilson J, Dewey W. Report of the commissioners appointed by the legislature of the state of New York, by the act of May 11, 1846, to locate certain portions of the New York and Erie railroad, made to the legislature, January 14, 1847 Journal of the Franklin Institute. 43: 289-301. DOI: 10.1016/0016-0032(47)90293-7  0.042
1977 End DW, Thoursen K, Dewey WL, Carchman RA. A comparative study of the disposition of (-)-delta 9-tetrahydrocannabinol in neuroblastoma and glioma cells in tissue culture: relation cellular impairment. Molecular Pharmacology. 13: 864-71. PMID 895721  0.036
1973 Williams BO, Eckel FM, Dewey WL. The need for an adverse drug reaction prediction and prevention program. American Journal of Hospital Pharmacy. 30: 124-7. PMID 4690466  0.03
1967 Harris LS, Dewey WL. Chapter 4. Analgetics - Strong and Weak Annual Reports in Medicinal Chemistry. 2: 33-43. DOI: 10.1016/S0065-7743(08)60247-X  0.024
1990 Dewey WL. Animals in research (II) Faseb Journal. 4: 2684.  0.023
1990 Zimmerman RS, Hayes RL, Morris DL, Lyeth BG, Dewey WL, Young HF. β-Endorphin in Cerebrospinal Fluid and Serum after Severe Head Injury Neurosurgery. 26: 764-770. DOI: 10.1227/00006123-199005000-00005  0.01
2011 Dewey W, Davis JP, Cheney DC. Shellfish Aquaculture and the Environment: An Industry Perspective Shellfish Aquaculture and the Environment. 33-50. DOI: 10.1002/9780470960967.ch2  0.01
1989 Dewey WL. Welcome and current status of CPDD Nida Research Monograph Series. 1-5.  0.01
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