Year |
Citation |
Score |
2012 |
Azad BB, Ashique R, Labiris NR, Chirakal R. Temperature effects on the stereospecificity of nucleophilic fluorination: formation of trans‐[18F]4‐fluoro‐l‐proline during the synthesis of cis‐[18F]4‐fluoro‐l‐proline Journal of Labelled Compounds and Radiopharmaceuticals. 55: 23-28. DOI: 10.1002/Jlcr.1947 |
0.595 |
|
2010 |
Vasdev N, Moran MD, Tuononen HM, Chirakal R, Suontamo RJ, Bain AD, Schrobilgen GJ. NMR spectroscopic evidence for the intermediacy of XeF(3)(-) in XeF(2)/F(-) exchange, attempted syntheses and thermochemistry of XeF(3)(-) salts, and theoretical studies of the XeF(3)(-) anion. Inorganic Chemistry. 49: 8997-9004. PMID 20799721 DOI: 10.1021/Ic101275M |
0.773 |
|
2010 |
Vasdev N, Chirakal R, Schrobilgen GJ, Nahmias C. ChemInform Abstract: Selectivity of Elemental Fluorine Towards L-Tyrosine and L-α-Methyltyrosine in Acidic Media and the Syntheses of Their [18F]3-Fluoro and [18F]3,5-Difluoro Derivatives. Cheminform. 33: no-no. DOI: 10.1002/CHIN.200220158 |
0.734 |
|
2009 |
Ashique R, Chirakal R, Schrobilgen GJ, Hughes DW, Farncombe T, Gulenchyn K, Labiris R, Truman T, Saab C. Reactivity and selectivity of F2 toward 3,4,6-Tri-O-acetyl-D-Glucal in anhydrous HF: Synthesis of [18F]2-fluoro-2-deoxy-β- D-allose and its use for the detection of a breast tumor Acs Symposium Series. 1003: 211-235. DOI: 10.1021/bk-2009-1003.ch010 |
0.595 |
|
2008 |
Jager PL, Chirakal R, Marriott CJ, Brouwers AH, Koopmans KP, Gulenchyn KY. 6-L-18F-fluorodihydroxyphenylalanine PET in neuroendocrine tumors: basic aspects and emerging clinical applications. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 573-86. PMID 18344441 DOI: 10.2967/Jnumed.107.045708 |
0.509 |
|
2008 |
Behnam Azad B, Ashique R, Chirakal R, Schrobilgen GJ. Selective fluorination of m-tyrosine by OF2 Journal of Fluorine Chemistry. 129: 22-27. DOI: 10.1016/J.Jfluchem.2007.08.004 |
0.732 |
|
2007 |
Azad BB, Chirakal R, Schrobilgen GJ. Trifluoromethanesulfonic acid, an alternative solvent medium for the direct electrophilic fluorination of DOPA: New syntheses of 6-[18F]fluoro- L-DOPA and 6-[18F]fluoro-D-DOPA Journal of Labelled Compounds and Radiopharmaceuticals. 50: 1236-1242. DOI: 10.1002/Jlcr.1454 |
0.769 |
|
2006 |
Guenther KJ, Yoganathan S, Garofalo R, Kawabata T, Strack T, Labiris R, Dolovich M, Chirakal R, Valliant JF. Synthesis and in vitro evaluation of 18F- and 19F-labeled insulin: a new radiotracer for PET-based molecular imaging studies. Journal of Medicinal Chemistry. 49: 1466-74. PMID 16480283 DOI: 10.1021/Jm0509344 |
0.394 |
|
2006 |
Ashique R, Chirakal RV, Hughes DW, Schrobilgen GJ. Two-step regio- and stereoselective syntheses of [19F]- and [18F]-2-deoxy-2-(R)-fluoro-beta-D-allose. Carbohydrate Research. 341: 457-66. PMID 16413000 DOI: 10.1016/J.Carres.2005.12.002 |
0.664 |
|
2004 |
Mamo D, Remington G, Nobrega J, Hussey D, Chirakal R, Wilson AA, Baker G, Houle S, Kapur S. Effect of acute antipsychotic administration on dopamine synthesis in rodents and human subjects using 6-[18F]-L-m-tyrosine. Synapse (New York, N.Y.). 52: 153-62. PMID 15034921 DOI: 10.1002/Syn.20016 |
0.474 |
|
2003 |
Mamo D, Chirakal R, Wilson A, Hussey D, Kapur S. The effect of single-dose risperidone on aromatic amino acid decar☐ylase activity in healthy human subjects measured using [18F]6-fluoro-L-M-tyrosine positron emission tomography Schizophrenia Research. 60: 243. DOI: 10.1016/S0920-9964(03)81251-3 |
0.493 |
|
2003 |
Vasdev N, Chirakal R, Ashique R, Schrobilgen GJ, Gulenchyn K. Syntheses of [18F]5-fluoro-3-nitro-L-tyrosine Journal of Fluorine Chemistry. 121: 9-14. DOI: 10.1016/S0022-1139(02)00334-2 |
0.801 |
|
2002 |
Vasdev N, Pointner BE, Chirakal R, Schrobilgen GJ. On the preparation of fluorine-18 labelled XeF(2) and chemical exchange between fluoride ion and XeF(2). Journal of the American Chemical Society. 124: 12863-8. PMID 12392433 DOI: 10.1021/Ja020604Y |
0.768 |
|
2002 |
Vasdev N, Pointner BE, Chirakal R, Schrobilgen GJ. On the preparation of fluorine-18 labelled XeF2 and chemical exchange between fluoride ion and XeF2 Journal of the American Chemical Society. 124: 12863-12868. DOI: 10.1021/ja020604y |
0.604 |
|
2002 |
Chirakal R, Vasdev N, Asselin MC, Schrobilgen GJ, Nahmias C. The effect of aromatic fluorine substitution in L-DOPA on the in vivo behaviour of [18F]2-, [18F]5- and [18F]6-fluoro-L-DOPA in the human brain Journal of Fluorine Chemistry. 115: 33-39. DOI: 10.1016/S0022-1139(02)00025-8 |
0.795 |
|
2001 |
Vasdev N, Chirakal R, Schrobilgen GJ, Nahmias C. Selectivity of elemental fluorine towards L-tyrosine and L-α-methyltyrosine in acidic media and the syntheses of their [18F]3-fluoro and [18F]3,5-difluoro derivatives Journal of Fluorine Chemistry. 111: 17-25. DOI: 10.1016/S0022-1139(01)00406-7 |
0.754 |
|
2001 |
Chirakal R, Vasdev N, Schrobilgen GJ, Amano S, Nahmias C. A comparative study of the in vivo behaviour of [18F] 2-, 5- and 6-fluoro-L-dopa in the human brain Journal of Labelled Compounds and Radiopharmaceuticals. 44: S219-S221. DOI: 10.1002/Jlcr.2580440176 |
0.751 |
|
2001 |
Vasdev N, Chirakal R, Schrobilgen GJ, Nahmias C. Selectivity of [18F]F2 towards L-α-methyltyrosine and L-tyrosine: A radiochemical and NMR spectroscopic study Journal of Labelled Compounds and Radiopharmaceuticals. 44: S863-S865. DOI: 10.1002/Jlcr.25804401303 |
0.785 |
|
1999 |
Wahl LM, Chen JJ, Thompson M, Chirakal R, Nahmias C. The time course of metabolites in human plasma after 6-[18F]fluoro-L-m-tyrosine administration European Journal of Nuclear Medicine. 26: 1407-1412. PMID 10552081 DOI: 10.1007/S002590050472 |
0.45 |
|
1999 |
Fallen EL, Coates G, Nahmias C, Chirakal R, Beanlands R, Wahl L, Woodcock G, Thomson M, Kamath M. Recovery rates of regional sympathetic reinnervation and myocardial blood flow after acute myocardial infarction American Heart Journal. 137: 863-869. PMID 10220635 DOI: 10.1016/S0002-8703(99)70410-2 |
0.338 |
|
1999 |
Chirakal R, Vasdev N, Schrobilgen GJ, Nahmias C. Radiochemical and NMR spectroscopic investigation of the solvent effect on the electrophilic elemental fluorination of L-DOPA: Synthesis of [ 18F ]5-fluoro-L-DOPA Journal of Fluorine Chemistry. 99: 87-94. DOI: 10.1016/S0022-1139(99)00123-2 |
0.726 |
|
1998 |
Lui E, Chirakal R, Firnau G. Enzymatic synthesis of (−)-6-[18F]-fluoronorepinephrine from 6-[18F]-fluorodopamine by dopamine β-hydroxylase Journal of Labelled Compounds and Radiopharmaceuticals. 41: 503-521. DOI: 10.1002/(Sici)1099-1344(199806)41:6<503::Aid-Jlcr107>3.0.Co;2-I |
0.611 |
|
1996 |
Chirakal R, Coates G, Firnau G, Schrobilgen GJ, Nahmias C. Direct radiofluorination of dopamine: 18F-labeled 6-fluorodopamine for imaging cardiac sympathetic innervation in humans using positron emission tomography. Nuclear Medicine and Biology. 23: 41-5. PMID 9004913 DOI: 10.1016/0969-8051(95)00213-8 |
0.732 |
|
1996 |
Coates G, Chirakal R, Fallen EL, Firnau G, Garnett ES, Kamath MV, Scheffel A, Nahmias C. Regional distribution and kinetics of [18F]6-flurodopamine as a measure of cardiac sympathetic activity in humans Heart. 75: 29-34. PMID 8624867 DOI: 10.1136/Hrt.75.1.29 |
0.603 |
|
1995 |
Chirakal R, Adams RM, Firnau G, Schrobilgen GJ, Coates G, Garnett ES. Electrophilic 18F from a Siemens 11 MeV proton-only cyclotron. Nuclear Medicine and Biology. 22: 111-6. PMID 7735160 DOI: 10.1016/0969-8051(94)E0064-P |
0.692 |
|
1995 |
Nahmias C, Wahl L, Chirakal R, Firnau G, Garnett ES. A probe for intracerebral aromatic amino-acid decarboxylase activity: Distribution and kinetics of [18F]6-fluoro-L-m-tyrosine in the human brain Movement Disorders. 10: 298-304. PMID 7651447 DOI: 10.1002/Mds.870100312 |
0.532 |
|
1995 |
Chirakal R, McCarry B, Lonegran M, Firnau G, Garnett S. Base-mediated decomposition of a Mannose triflate during the synthesis of 2-deoxy-2-18F-fluoro-d-glucose Applied Radiation and Isotopes. 46: 149-155. DOI: 10.1016/0969-8043(94)00128-M |
0.6 |
|
1994 |
Wahl L, Chirakal R, Firnau G, Garnett ES, Nahmias C. The distribution and kinetics of [18F]6-Fluoro-3-O-methyl-L-dopa in the human brain Journal of Cerebral Blood Flow and Metabolism. 14: 664-670. PMID 8014214 DOI: 10.1038/Jcbfm.1994.83 |
0.544 |
|
1991 |
Chirakal R, Schrobilgen GJ, Firnau G, Garnett S. Synthesis of 18F labelled fluoro-m-tyrosine, fluoro-m-tyramine and fluoro-3-hydroxyphenylacetic acid International Journal of Radiation Applications and Instrumentation. Part. 42: 113-119. DOI: 10.1016/0883-2889(91)90059-A |
0.713 |
|
1990 |
Firnau G, Chirakal R, Nahmias C, Brown K, Garnett ES. New 18F tracers for the investigation of brain functions Acta Radiologica, Supplement. 374: 37-41. PMID 1966968 |
0.546 |
|
1990 |
Christe KO, Wilson WW, Chirakal RV, Sanders JCP, Schrobilgen GJ. The hexafluorochlorate(V) anion, ClF6 - Inorganic Chemistry. 29: 3506-3511. DOI: 10.1021/Ic00343A044 |
0.669 |
|
1990 |
CHRISTE KO, WILSON WW, CHIRAKAL RV, SANDERS JCP, SCHROBILGEN GJ. ChemInform Abstract: The Hexafluorochlorate(V) Anion, ClF- 6. Cheminform. 21. DOI: 10.1002/chin.199048022 |
0.404 |
|
1989 |
Chirakal R, Firnau G, Garnett E, Schrobilgen G. Direct elemental fluorination of tyrosine in HF and HF/BF3. Reactivity and selectivity Journal of Fluorine Chemistry. 45: 125. DOI: 10.1016/S0022-1139(00)84497-8 |
0.577 |
|
1989 |
Chirakal R, Firnau G, Garnett E. A positron emitting inhibitor of aromatic L-aminoacid decarboxylase: α-fluoromethyl-6-[F-18]fluoro-L-DOPA Journal of Labelled Compounds and Radiopharmaceuticals. 26: 228-229. DOI: 10.1002/Jlcr.25802601103 |
0.578 |
|
1988 |
Firnau G, Sood S, Chirakal R, Nahmias C, Garnett ES. Metabolites of 6-[18F]fluoro-L-dopa in human blood Journal of Nuclear Medicine. 29: 363-369. PMID 3126278 |
0.598 |
|
1988 |
Christe KO, Wilson WW, Schrobilgen GJ, Chirakal RV, Olah GA. On the existence of pentacoordinated nitrogen Inorganic Chemistry. 27: 789-790. DOI: 10.1021/Ic00278A009 |
0.506 |
|
1988 |
Christe KO, Wilson WW, Schrobilgen GJ, Chirakal RV, Olah GA. On the existence of pentacoordinated nitrogen Inorganic Chemistry. 27: 789-790. DOI: 10.1021/ic00278a009 |
0.364 |
|
1988 |
Chirakal R, Firnau G, Garnett E. Sequential production of electrophilic and nucleophilic fluorinating agents from [18F]fluorine gas International Journal of Radiation Applications and Instrumentation. Part a. Applied Radiation and Isotopes. 39: 1099-1101. DOI: 10.1016/0883-2889(88)90149-9 |
0.626 |
|
1988 |
Chirakal R, Sayer BG, Firnau G, Garnett ES. Synthesis of f-18 labelled fluoro-melatonins and 5-hydroxy-fluoro-tryptophans Journal of Labelled Compounds and Radiopharmaceuticals. 25: 63-71. DOI: 10.1002/Jlcr.2580250108 |
0.521 |
|
1987 |
Garnett ES, Lang AE, Chirakal R, Firnau G, Nahmias C. A rostrocaudal gradient for aromatic acid decarboxylase in the human striatum Canadian Journal of Neurological Sciences. 14: 444-447. PMID 3119181 DOI: 10.1017/S0317167100037884 |
0.556 |
|
1987 |
Firnau G, Sood S, Chirakal R, Nahmias C, Garnett ES. Cerebral Metabolism of 6–[18F]Fluoro‐l‐3,4‐Dihydroxyphenylalanine in the Primate Journal of Neurochemistry. 48: 1077-1082. PMID 3102690 DOI: 10.1111/J.1471-4159.1987.Tb05629.X |
0.608 |
|
1987 |
Chirakal R, Brown K, Firnau G, Garnett E, Hughes D, Sayer B, Smith R. Synthesis of 2- and 3-fluorotyrosine with dilute fluorine gas Journal of Fluorine Chemistry. 37: 267-278. DOI: 10.1016/S0022-1139(00)82023-0 |
0.557 |
|
1986 |
Firnau G, Garnett ES, Chirakal R, Sood S, Nahmias C, Schrobilgen G. [18F]fluoro-L-dopa for the in vivo study of intracerebral dopamine. International Journal of Radiation Applications and Instrumentation. Part a, Applied Radiation and Isotopes. 37: 669-75. PMID 3021668 DOI: 10.1016/0883-2889(86)90260-1 |
0.69 |
|
1984 |
Chirakal R, Firnau G, Couse J, Garnett E. Radiofluorination with 18F-labelled acetyl hypofluorite: [18F]L-6-fluorodopa The International Journal of Applied Radiation and Isotopes. 35: 651-653. DOI: 10.1016/0020-708X(84)90111-X |
0.661 |
|
1984 |
Chirakal R, Firnau G, Schrobilgen GJ, Mckay J, Garnett ES. The synthesis of [18F]Xenon difluoride from [18F]fluoride gas The International Journal of Applied Radiation and Isotopes. 35: 401-404. DOI: 10.1016/0020-708X(84)90049-8 |
0.743 |
|
1983 |
Garnett S, Firnau G, Nahmias C, Chirakal R. Striatal dopamine metabolism in living monkeys examined by positron emission tomography Brain Research. 280: 169-171. PMID 6418330 DOI: 10.1016/0006-8993(83)91187-3 |
0.564 |
|
1981 |
Firnau GSG, Chirakal R, Garnett ES. Synthesis of [18F]XeF2, a novel agent for the preparation of 18F-radiopharmaceuticals Journal of the Chemical Society, Chemical Communications. 198-199. DOI: 10.1039/C39810000198 |
0.648 |
|
1981 |
SCHROBILGEN G, FIRNAU G, CHIRAKAL R, GARNETT ES. ChemInform Abstract: SYNTHESIS OF XENON DIFLUORIDE-18F, A NOVEL AGENT FOR THE PREPARATION OF FLUORINE-18 RADIOPHARMACEUTICALS Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198125038 |
0.685 |
|
1980 |
Firnau G, Chirakal R, Sood S, Garnett S. Aromatic fluorination with xenon difluoride: L-3,4-dihydroxy-6-fluoro-phenylalanine Canadian Journal of Chemistry. 58: 1449-1450. DOI: 10.1139/V80-228 |
0.433 |
|
1980 |
FIRANAU G, CHIRAKAL R, SOOD S, GARNETT S. ChemInform Abstract: AROMATIC FLUORINATION OF XENON DIFLUORIDE: L-3,4-DIHYDROXY-6-FLUORO-PHENYLALANINE Chemischer Informationsdienst. 11. DOI: 10.1002/Chin.198048294 |
0.452 |
|
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