Ashish Dhir, Ph.D. - Publications

Affiliations: 
Neurology University of California, Davis, Davis, CA 
Area:
Epilepsy

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Guignet M, Dhakal K, Flannery BM, Hobson BA, Zolkowska D, Dhir A, Bruun DA, Li S, Wahab A, Harvey DJ, Silverman JL, Rogawski MA, Lein PJ. Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication. Neurobiology of Disease. PMID 30905768 DOI: 10.1016/j.nbd.2019.03.019  1
2018 Dhir A, Rogawski MA. Determination of minimal steady-state plasma level of diazepam causing seizure threshold elevation in rats. Epilepsia. PMID 29682729 DOI: 10.1111/epi.14069  1
2016 Dhir A, Chavda V. Pre- and post-exposure talampanel (GYKI 53773) against kainic acid seizures in neonatal rats. Pharmacological Reports : Pr. 68: 190-5. PMID 26721372 DOI: 10.1016/j.pharep.2015.08.011  1
2015 Dhir A, Chopra K. On the anticonvulsant effect of allopregnanolone (a neurosteroid) in neonatal rats. Life Sciences. PMID 26400153 DOI: 10.1016/j.lfs.2015.09.008  1
2015 Dhir A, Chopra K. Memantine delayed N-methyl-D-aspartate -induced convulsions in neonatal rats. Fundamental & Clinical Pharmacology. 29: 72-8. PMID 25196574 DOI: 10.1111/fcp.12090  1
2014 Dhir A, Sarvaiya J. The efficacy of vortioxetine for the treatment of major depressive disorder. Expert Review of Neurotherapeutics. 14: 1349-63. PMID 25418918 DOI: 10.1586/14737175.2014.987131  1
2014 Zolkowska D, Dhir A, Krishnan K, Covey DF, Rogawski MA. Anticonvulsant potencies of the enantiomers of the neurosteroids androsterone and etiocholanolone exceed those of the natural forms. Psychopharmacology. 231: 3325-32. PMID 24705905 DOI: 10.1007/s00213-014-3546-x  1
2014 Dhir A, Kulkarni SK. Nimesulide, a cyclooxygenase-2 (COX-2) inhibitor counteracts immobilization stress-induced alterations in different behavioral and biochemical parameters in mice Inflammation Research. 56: S481-S487. DOI: 10.1007/BF03353885  1
2013 Dhir A. Vortioxetine for the treatment of major depression. Drugs of Today (Barcelona, Spain : 1998). 49: 781-90. PMID 24524096 DOI: 10.1358/dot.2013.49.12.2058448  1
2013 Dhir A, Zolkowska D, Rogawski MA. Seizure protection by intrapulmonary delivery of midazolam in mice. Neuropharmacology. 73: 425-31. PMID 23774136 DOI: 10.1016/j.neuropharm.2013.06.002  1
2013 Pathak L, Agrawal Y, Dhir A. Natural polyphenols in the management of major depression. Expert Opinion On Investigational Drugs. 22: 863-80. PMID 23642183 DOI: 10.1517/13543784.2013.794783  1
2012 Dhir A. Pentylenetetrazol (PTZ) kindling model of epilepsy. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit9.37. PMID 23042503 DOI: 10.1002/0471142301.ns0937s58  1
2012 Porter RJ, Dhir A, Macdonald RL, Rogawski MA. Mechanisms of action of antiseizure drugs. Handbook of Clinical Neurology. 108: 663-81. PMID 22939059 DOI: 10.1016/B978-0-444-52899-5.00021-6  1
2012 Dhir A, Lossin C, Rogawski MA. Propofol hemisuccinate suppresses cortical spreading depression. Neuroscience Letters. 514: 67-70. PMID 22390898 DOI: 10.1016/j.neulet.2012.02.058  1
2012 Zolkowska D, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, Rogawski MA. Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine. The Journal of Pharmacology and Experimental Therapeutics. 341: 435-46. PMID 22328574 DOI: 10.1124/jpet.111.190579  1
2012 Dhir A, Rogawski MA. Role of neurosteroids in the anticonvulsant activity of midazolam. British Journal of Pharmacology. 165: 2684-91. PMID 22014182 DOI: 10.1111/j.1476-5381.2011.01733.x  1
2012 Dhir A. Progress in epilepsy research: 65th Annual Meeting of the American Epilepsy Society, December 2-6, 2011, Baltimore, Maryland, USA Drugs of the Future. 37: 221-224. DOI: 10.1358/dof.2012.037.03.1769834  1
2012 Dhir A. AMPA receptor antagonist antiepileptic agent Drugs of the Future. 37: 13-17. DOI: 10.1358/dof.2012.037.01.1709374  1
2011 Pissurlenkar RS, Dhir A, Kessar SV, Kulkarni SK, Coutinho EC. An activity model for novel antidepressants that interact with the serotonin transporter (SERT). Central Nervous System Agents in Medicinal Chemistry. 11: 228-37. PMID 21919867  1
2011 Kulkarni SK, Dhir A. Animal models of tardive dyskinesia. International Review of Neurobiology. 98: 265-87. PMID 21907091 DOI: 10.1016/B978-0-12-381328-2.00011-0  1
2011 Dhir A, Kulkarni SK. Antidepressant-like effect of 1-(7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-YL)-cyclohexanol, a putative trace amine receptor ligand involves l-arginine-nitric oxide-cyclic guanosine monophosphate pathway. Neuroscience Letters. 503: 120-4. PMID 21875647 DOI: 10.1016/j.neulet.2011.08.020  1
2011 Dhir A, Kulkarni SK. Nitric oxide and major depression. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 24: 125-31. PMID 21335097 DOI: 10.1016/j.niox.2011.02.002  1
2011 Dhir A, Malik S, Kessar SV, Singh KN, Kulkarni SK. Evaluation of antidepressant activity of 1-(7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-YL)-cyclohexanol, a β-substituted phenylethylamine in mice. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 21: 705-14. PMID 21277753 DOI: 10.1016/j.euroneuro.2010.12.003  1
2011 Dhir A, Zolkowska D, Murphy RB, Rogawski MA. Seizure protection by intrapulmonary delivery of propofol hemisuccinate. The Journal of Pharmacology and Experimental Therapeutics. 336: 215-22. PMID 20837991 DOI: 10.1124/jpet.110.173591  1
2011 Dhir A. Highlights in epilepsy research: Current topics from the 136th Annual Meeting of the American Neurological Association, September 25-27, 2011 Drugs of the Future. 36: 655-658. DOI: 10.1358/dof.2011.036.11.1717925  1
2011 Dhir A. Advances in epilepsy research: 64th Annual Meeting of the American Epilepsy Society, San Antonio, Texas, USA Drugs of the Future. 36: 341-345. DOI: 10.1358/dof.2011.036.04.1626643  1
2010 Gupta A, Dhir A, Kumar A, Kulkarni SK. Effect of preferential cyclooxygenase-2 (COX-2) inhibitor against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced striatal lesions in rats: behavioral, biochemical and histological evidences. Indian Journal of Experimental Biology. 48: 577-85. PMID 20882760  1
2010 Kulkarni SK, Dhir A. An overview of curcumin in neurological disorders. Indian Journal of Pharmaceutical Sciences. 72: 149-54. PMID 20838516 DOI: 10.4103/0250-474X.65012  1
2010 Dhir A. Novel discoveries in understanding the complexities of epilepsy and major depression. Expert Opinion On Therapeutic Targets. 14: 109-15. PMID 20001214 DOI: 10.1517/14728220903479688  1
2010 Kulkarni SK, Dhir A. Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders. Phytotherapy Research : Ptr. 24: 317-24. PMID 19998323 DOI: 10.1002/ptr.2968  1
2010 Dhir A. New therapeutic approaches in epilepsy and comorbid disorders: Highlights of the 63rd Annual Meeting of the American Epilepsy Society Drugs of the Future. 35: 155-159. DOI: 10.1358/dof.2010.035.02.1468917  1
2009 Akula KK, Dhir A, Kulkarni SK. Effect of various antiepileptic drugs in a pentylenetetrazol-induced seizure model in mice. Methods and Findings in Experimental and Clinical Pharmacology. 31: 423-32. PMID 19907717 DOI: 10.1358/mf.2009.31.7.1393610  1
2009 Kulkarni S, Dhir A, Akula KK. Potentials of curcumin as an antidepressant. Thescientificworldjournal. 9: 1233-41. PMID 19882093 DOI: 10.1100/tsw.2009.137  1
2009 Gupta A, Dhir A, Kumar A, Kulkarni SK. Protective effect of cyclooxygenase (COX)-inhibitors against drug-induced catatonia and MPTP-induced striatal lesions in rats. Pharmacology, Biochemistry, and Behavior. 94: 219-26. PMID 19666045 DOI: 10.1016/j.pbb.2009.07.018  1
2009 Kulkarni SK, Dhir A. sigma-1 receptors in major depression and anxiety. Expert Review of Neurotherapeutics. 9: 1021-34. PMID 19589051 DOI: 10.1586/ern.09.40  1
2009 Nandal S, Dhir A, Kuhad A, Sharma S, Chopra K. Curcumin potentiates the anti-inflammatory activity of cyclooxygenase inhibitors in the cotton pellet granuloma pouch model. Methods and Findings in Experimental and Clinical Pharmacology. 31: 89-93. PMID 19455263 DOI: 10.1358/mf.2009.31.2.1357705  1
2009 Kulkarni SK, Dhir A. Current investigational drugs for major depression. Expert Opinion On Investigational Drugs. 18: 767-88. PMID 19426122 DOI: 10.1517/13543780902880850  1
2009 Kulkarni SK, Dhir A. Cyclooxygenase in epilepsy: from perception to application. Drugs of Today (Barcelona, Spain : 1998). 45: 135-54. PMID 19343233 DOI: 10.1358/dot.2009.45.2.1322481  1
2008 Kulkarni SK, Deshpande C, Dhir A. Ascorbic Acid inhibits development of tolerance and dependence to opiates in mice: possible glutamatergic or dopaminergic modulation. Indian Journal of Pharmaceutical Sciences. 70: 56-60. PMID 20390081 DOI: 10.4103/0250-474X.40332  1
2008 Dhir A, Kulkarni SK. New therapeutic promises in the treatment of depression and schizophrenia. Drug News & Perspectives. 21: 581-92. PMID 19221639  1
2008 Dhir A, Kulkarni SK. Antidepressant-like effect of 17beta-estradiol: involvement of dopaminergic, serotonergic, and (or) sigma-1 receptor systems. Canadian Journal of Physiology and Pharmacology. 86: 726-35. PMID 18841177 DOI: 10.1139/y08-077  1
2008 Dhir A, Kulkarni SK. Risperidone, an atypical antipsychotic enhances the antidepressant-like effect of venlafaxine or fluoxetine: possible involvement of alpha-2 adrenergic receptors. Neuroscience Letters. 445: 83-8. PMID 18778754 DOI: 10.1016/j.neulet.2008.08.074  1
2008 Dhir A, Kulkarni SK. Possible involvement of sigma-1 receptors in the anti-immobility action of bupropion, a dopamine reuptake inhibitor. Fundamental & Clinical Pharmacology. 22: 387-94. PMID 18705749 DOI: 10.1111/j.1472-8206.2008.00605.x  1
2008 Kulkarni SK, Akula KK, Dhir A. Effect of Withania somnifera Dunal root extract against pentylenetetrazol seizure threshold in mice: possible involvement of GABAergic system. Indian Journal of Experimental Biology. 46: 465-9. PMID 18697606  1
2008 Kulkarni SK, Dhir A. On the mechanism of antidepressant-like action of berberine chloride. European Journal of Pharmacology. 589: 163-72. PMID 18585703 DOI: 10.1016/j.ejphar.2008.05.043  1
2008 Akula KK, Dhir A, Kulkarni SK. Nitric oxide signaling pathway in the anti-convulsant effect of adenosine against pentylenetetrazol-induced seizure threshold in mice. European Journal of Pharmacology. 587: 129-34. PMID 18457833 DOI: 10.1016/j.ejphar.2008.03.038  1
2008 Dhir A, Kulkarni SK. Possible involvement of nitric oxide (NO) signaling pathway in the antidepressant-like effect of MK-801(dizocilpine), a NMDA receptor antagonist in mouse forced swim test. Indian Journal of Experimental Biology. 46: 164-70. PMID 18432055  1
2008 Dhir A, Akula KK, Kulkarni SK. Rofecoxib potentiates the anticonvulsant effect of topiramate. Inflammopharmacology. 16: 83-6. PMID 18340407 DOI: 10.1007/s10787-007-7007-6  1
2008 Dhir A, Kulkarni SK. Venlafaxine reverses chronic fatigue-induced behavioral, biochemical and neurochemical alterations in mice. Pharmacology, Biochemistry, and Behavior. 89: 563-71. PMID 18336891 DOI: 10.1016/j.pbb.2008.02.011  1
2008 Dhir A, Kulkarni S. Involvement of sigma (sigma1) receptors in modulating the anti-depressant effect of neurosteroids (dehydroepiandrosterone or pregnenolone) in mouse tail-suspension test. Journal of Psychopharmacology (Oxford, England). 22: 691-6. PMID 18308813 DOI: 10.1177/0269881107082771  1
2008 Dhir A, Akula KK, Kulkarni SK. Tiagabine, a GABA uptake inhibitor, attenuates 3-nitropropionic acid-induced alterations in various behavioral and biochemical parameters in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 32: 835-43. PMID 18234412 DOI: 10.1016/j.pnpbp.2007.12.017  1
2008 Akula KK, Dhir A, Kulkarni SK. Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor increases pentylenetetrazol seizure threshold in mice: possible involvement of adenosinergic mechanism. Epilepsy Research. 78: 60-70. PMID 18054463 DOI: 10.1016/j.eplepsyres.2007.10.008  1
2008 Kulkarni SK, Dhir A. Withania somnifera: an Indian ginseng. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 32: 1093-105. PMID 17959291 DOI: 10.1016/j.pnpbp.2007.09.011  1
2008 Kulkarni SK, Dhir A. Studies on the antidepressant activity of berberine chloride in animals Indian Drugs. 45: 199-206.  1
2007 Kumari B, Kumar A, Dhir A. Protective effect of non-selective and selective COX-2-inhibitors in acute immobilization stress-induced behavioral and biochemical alterations. Pharmacological Reports : Pr. 59: 699-707. PMID 18195459  1
2007 Akula KK, Dhir A, Kulkarni SK. Systemic administration of adenosine ameliorates pentylenetetrazol-induced chemical kindling and secondary behavioural and biochemical changes in mice. Fundamental & Clinical Pharmacology. 21: 583-94. PMID 18034659 DOI: 10.1111/j.1472-8206.2007.00540.x  1
2007 Akula KK, Dhir A, Kulkarni SK. Pro-convulsant effect of cefazolin sodium against pentylenetetrazol- or picrotoxin-induced convulsions in mice. Indian Journal of Experimental Biology. 45: 720-5. PMID 17877149  1
2007 Kulkarni SK, Kaushal A, Dhir A. Effect of withdrawal of diazepam or morphine treatment on gastric motility (charcoal meal test) in mice: possible role of different central and peripheral receptors. Indian Journal of Experimental Biology. 45: 642-8. PMID 17821862  1
2007 Akula KK, Dhir A, Bishnoi M, Kulkarni SK. Effect of systemic administration of adenosine on brain adenosine levels in pentylenetetrazol-induced seizure threshold in mice. Neuroscience Letters. 425: 39-42. PMID 17720312 DOI: 10.1016/j.neulet.2007.08.006  1
2007 Dhir A, Kulkarni SK. Involvement of dopamine (DA)/serotonin (5-HT)/sigma (sigma) receptor modulation in mediating the antidepressant action of ropinirole hydrochloride, a D2/D3 dopamine receptor agonist. Brain Research Bulletin. 74: 58-65. PMID 17683790 DOI: 10.1016/j.brainresbull.2007.05.004  1
2007 Dhir A, Kulkarni SK. Effect of addition of yohimbine (alpha-2-receptor antagonist) to the antidepressant activity of fluoxetine or venlafaxine in the mouse forced swim test. Pharmacology. 80: 239-43. PMID 17622775 DOI: 10.1159/000104877  1
2007 Dhir A, Naidu PS, Kulkarni SK. Neuroprotective effect of nimesulide, a preferential COX-2 inhibitor, against pentylenetetrazol (PTZ)-induced chemical kindling and associated biochemical parameters in mice. Seizure. 16: 691-7. PMID 17604186 DOI: 10.1016/j.seizure.2007.05.016  1
2007 Kulkarni SK, Dhir A. Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant activity of berberine chloride. European Journal of Pharmacology. 569: 77-83. PMID 17585901 DOI: 10.1016/j.ejphar.2007.05.002  1
2007 Kulkarni SK, Dhir A. Effect of various classes of antidepressants in behavioral paradigms of despair. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 1248-54. PMID 17570574 DOI: 10.1016/j.pnpbp.2007.05.002  1
2007 Dhir A, Kulkarni SK. Involvement of sigma-1 receptor modulation in the antidepressant action of venlafaxine. Neuroscience Letters. 420: 204-8. PMID 17532136 DOI: 10.1016/j.neulet.2007.04.055  1
2007 Dhir A, Kulkarni SK. Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of bupropion, a dopamine reuptake inhibitor. European Journal of Pharmacology. 568: 177-85. PMID 17509558 DOI: 10.1016/j.ejphar.2007.04.028  1
2007 Dhir A, Kulkarni SK. Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of venlafaxine in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 921-5. PMID 17379375 DOI: 10.1016/j.pnpbp.2007.02.008  1
2006 Dhir A, Kulkarni SK. Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor potentiates the anticonvulsant activity of tiagabine against pentylenetetrazol-induced convulsions in mice. Inflammopharmacology. 14: 222-5. PMID 17139446 DOI: 10.1007/s10787-006-1535-3  1
2006 Dhir A, Naidu PS, Kulkarni SK. Effect of cyclooxygenase inhibitors on pentylenetetrazol (PTZ)-induced convulsions: Possible mechanism of action. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 30: 1478-85. PMID 16844276 DOI: 10.1016/j.pnpbp.2006.06.003  1
2006 Dhir A, Naidu PS, Kulkarni SK. Effect of rofecoxib, a cyclo-oxygenase-2 inhibitor, on various biochemical parameters of brain associated with pentylenetetrazol-induced chemical kindling in mice. Fundamental & Clinical Pharmacology. 20: 255-61. PMID 16671960 DOI: 10.1111/j.1472-8206.2006.00398.x  1
2006 Dhir A, Naidu PS, Kulkarni SK. Effect of cyclooxygenase-2 (COX-2) inhibitors in various animal models (bicuculline, picrotoxin, maximal electroshock-induced convulsions) of epilepsy with possible mechanism of action. Indian Journal of Experimental Biology. 44: 286-91. PMID 16629370  1
2006 Deshpande C, Dhir A, Kulkarni SK. Antagonistic activity of ascorbic acid (vitamin C) on dopaminergic modulation: apomorphine-induced stereotypic behavior in mice. Pharmacology. 77: 38-45. PMID 16569938 DOI: 10.1159/000092409  1
2006 Dhir A, Padi SS, Naidu PS, Kulkarni SK. Protective effect of naproxen (non-selective COX-inhibitor) or rofecoxib (selective COX-2 inhibitor) on immobilization stress-induced behavioral and biochemical alterations in mice. European Journal of Pharmacology. 535: 192-8. PMID 16522321 DOI: 10.1016/j.ejphar.2006.01.064  1
2005 Dhir A, Naidu PS, Kulkarni SK. Protective effect of cyclooxygenase-2 (COX-2) inhibitors but not non-selective cyclooxygenase (COX)-inhibitors on ethanol withdrawal-induced behavioural changes. Addiction Biology. 10: 329-35. PMID 16318954 DOI: 10.1080/13556210500352964  1
2005 Dhir A, Naidu PS, Kulkarni SK. Effect of naproxen, a non-selective cyclo-oxygenase inhibitor, on pentylenetetrazol-induced kindling in mice. Clinical and Experimental Pharmacology & Physiology. 32: 574-84. PMID 16026518 DOI: 10.1111/j.1440-1681.2005.04233.x  1
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