Jose N. Nobrega - Publications

Affiliations: 
Pharmacology University of Toronto, Toronto, ON, Canada 
Area:
Pharmacology, Neuroscience Biology

177 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Nobrega JN, Raymond R, Rajji TK, Pollock BG. A calcium fluorescence assay for quantification of cholinergic receptor activity of clinical drugs in serum - comparison with radioactive methods. Journal of Pharmacological and Toxicological Methods. 107118. PMID 34481920 DOI: 10.1016/j.vascn.2021.107118  1
2021 Waye SC, Dinesh OC, Hasan SN, Conway JD, Raymond R, Nobrega JN, Blundell J, Bambico FR. Antidepressant action of transcranial direct current stimulation in olfactory bulbectomised adolescent rats. Journal of Psychopharmacology (Oxford, England). 2698811211000765. PMID 33908307 DOI: 10.1177/02698811211000765  1
2021 Chandramouleeshwaran S, Ahsan N, Raymond R, Nobrega JN, Wang W, Fischer CE, Flint AJ, Herrmann N, Kumar S, Lanctôt K, Mah L, Mulsant BH, Pollock BG, Rajji TK. Relationships Between a New Cultured Cell-Based Serum Anticholinergic Activity Assay and Anticholinergic Burden Scales or Cognitive Performance in Older Adults. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 33846084 DOI: 10.1016/j.jagp.2021.03.002  1
2020 Bani-Fatemi A, Raymond R, Adanty C, Dai N, Gerretsen P, Graff A, Nobrega JN, De Luca V. Global DNA methylation in suicidal ideation and suicide attempt in schizophrenia. Psychiatric Genetics. PMID 33399315 DOI: 10.1097/YPG.0000000000000273  1
2020 Vimalanathan A, Gidyk DC, Diwan M, Gouveia FV, Lipsman N, Giacobbe P, Nobrega JN, Hamani C. Endocannabinoid modulating drugs improve anxiety but not the expression of conditioned fear in a rodent model of post-traumatic stress disorder. Neuropharmacology. 166: 107965. PMID 31962287 DOI: 10.1016/J.Neuropharm.2020.107965  1
2020 Fugariu V, Zack MH, Nobrega JN, Fletcher PJ, Zeeb FD. Effects of exposure to chronic uncertainty and a sensitizing regimen of amphetamine injections on locomotion, decision-making, and dopamine receptors in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31905371 DOI: 10.1038/S41386-020-0599-X  1
2019 Mansouri E, Nobrega JN, Hill MN, Tyndale RF, Lee FS, Hendershot CS, Best LM, Di Ciano P, Balsevich G, Sloan ME, Kish SJ, Tong J, Le Foll B, Boileau I. D3 dopamine receptors and a missense mutation of fatty acid amide hydrolase linked in mouse and men: implication for addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31775159 DOI: 10.1038/S41386-019-0580-8  1
2019 Bambico FR, Li Z, Creed M, De Gregorio D, Diwan M, Li J, McNeill S, Gobbi G, Raymond R, Nobrega JN. A Key Role for Prefrontocortical Small Conductance Calcium-Activated Potassium Channels in Stress Adaptation and Rapid Antidepressant Response. Cerebral Cortex (New York, N.Y. : 1991). PMID 31504265 DOI: 10.1093/Cercor/Bhz187  1
2019 Nashed MG, Chatterjee D, Nguyen D, Oleinichenko D, Diwan M, Nobrega JN. Ethanol-induced changes in synaptic amino acid neurotransmitter levels in the nucleus accumbens of differentially sensitized mice. Psychopharmacology. PMID 31302721 DOI: 10.1007/S00213-019-05324-X  1
2019 Reyes-Garcés N, Diwan M, Boyaci E, Gomez-Rios GA, Bojko B, Nobrega JN, Bambico FR, Hamani C, Pawliszyn J. In vivo brain sampling using a microextraction probe reveals metabolic changes in rodents after deep brain stimulation. Analytical Chemistry. PMID 31265251 DOI: 10.1021/Acs.Analchem.9B01540  1
2019 Bambico FR, Li Z, Oliveira C, McNeill S, Diwan M, Raymond R, Nobrega JN. Rostrocaudal subregions of the ventral tegmental area are differentially impacted by chronic stress. Psychopharmacology. PMID 30796492 DOI: 10.1007/S00213-019-5177-8  1
2018 Bambico FR, Comai S, Hasan MSN, Conway JD, Darvish-Gane S, Hamani C, Gobbi G, Nobrega JN. High frequency stimulation of the anterior vermis modulates behavioural response to chronic stress: Involvement of the prefrontal cortex and dorsal raphe? Neurobiology of Disease. PMID 29727711 DOI: 10.1016/J.Nbd.2018.03.011  1
2018 Volle J, Bregman T, Scott B, Diwan M, Raymond R, Fletcher PJ, Nobrega JN, Hamani C. Deep brain stimulation and fluoxetine exert different long-term changes in the serotonergic system. Neuropharmacology. PMID 29505786 DOI: 10.1016/J.Neuropharm.2018.03.005  1
2018 Mooney SJ, Nobrega JN, Levitt AJ, Hynynen K. Antidepressant effects of focused ultrasound induced blood-brain-barrier opening. Behavioural Brain Research. PMID 29326057 DOI: 10.1016/J.Bbr.2018.01.004  0.01
2017 Bregman T, Nona C, Volle J, Diwan M, Raymond R, Fletcher PJ, Nobrega JN, Hamani C. Deep brain stimulation induces antidepressant-like effects in serotonin transporter knockout mice. Brain Stimulation. PMID 29174865 DOI: 10.1016/J.Brs.2017.11.008  1
2017 Nona CN, Nobrega JN. A role for nucleus accumbens glutamate in the expression but not the induction of behavioural sensitization to ethanol. Behavioural Brain Research. PMID 28919158 DOI: 10.1016/J.Bbr.2017.09.024  1
2017 Reznikov R, Bambico F, Diwan M, Raymond RJ, Nashed MG, Nobrega JN, Hamani C. Prefrontal Cortex Deep Brain Stimulation Improves Fear and Anxiety-Like Behaviour and Reduces Basolateral Amygdala Activity in a Preclinical Model of Post-Traumatic Stress Disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28862251 DOI: 10.1038/Npp.2017.207  1
2017 Wilson AA, Sadovski O, Nobrega JN, Raymond RJ, Bambico FR, Nashed MG, Garcia A, Bloomfield PM, Houle S, Mizrahi R, Tong J. Evaluation of a novel radiotracer for positron emission tomography imaging of reactive oxygen species in the central nervous system. Nuclear Medicine and Biology. 53: 14-20. PMID 28719807 DOI: 10.1016/J.Nucmedbio.2017.05.011  1
2017 Hamann M, Plank J, Richter F, Bode C, Smiljanic S, Creed M, Nobrega JN, Richter A. Alterations of M1 and M4 acetylcholine receptors in the genetically dystonic (dt(sz)) hamster and moderate antidystonic efficacy of M1 and M4 anticholinergics. Neuroscience. 357: 84-98. PMID 28596119 DOI: 10.1016/J.Neuroscience.2017.05.051  1
2017 Feldcamp LA, Boutros PC, Raymond R, Fletcher PJ, Nobrega JN, Wong AHC. Pdxdc1 modulates prepulse inhibition of acoustic startle in the mouse. Translational Psychiatry. 7: e1125. PMID 28485732 DOI: 10.1038/Tp.2017.85  1
2017 Gollan JK, Dong H, Bruno D, Nierenberg J, Nobrega JN, Grothe MJ, Pollock BG, Marmar CR, Teipel S, Csernansky JG, Pomara N. Basal forebrain mediated increase in brain CRF is associated with increased cholinergic tone and depression. Psychiatry Research. 264: 76-81. PMID 28477491 DOI: 10.1016/J.Pscychresns.2017.04.009  0.01
2017 Miksys S, Wadji FB, Tolledo EC, Remington G, Nobrega JN, Tyndale RF. Rat brain CYP2D enzymatic metabolism alters acute and chronic haloperidol side-effects by different mechanisms. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 28454738 DOI: 10.1016/J.Pnpbp.2017.04.030  1
2017 Nobrega JN, Raymond RJ, Pollock BG. An improved, high-efficiency assay for assessing serum anticholinergic activity using cultured cells stably expressing M1 receptors. Journal of Pharmacological and Toxicological Methods. 86: 28-33. PMID 28274871 DOI: 10.1016/J.Vascn.2017.03.001  1
2016 Nobrega JN, Hedayatmofidi PS, Lobo DS. Strong interactions between learned helplessness and risky decision-making in a rat gambling model. Scientific Reports. 6: 37304. PMID 27857171 DOI: 10.1038/Srep37304  0.01
2016 Tong J, Mizrahi R, Houle S, Kish SJ, Boileau I, Nobrega J, Rusjan PM, Wilson AA. Inhibition of fatty acid amide hydrolase by BIA 10-2474 in rat brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27650910 DOI: 10.1177/0271678X16668890  1
2016 Lister J, Andreazza AC, Navaid B, Wilson VS, Teo C, Nesarajah Y, Wilson AA, Nobrega JN, Fletcher PJ, Remington G. Lipoic Acid and Haloperidol-Induced Vacuous Chewing Movements: Implications for Prophylactic Antioxidant Use in Tardive Dyskinesia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 27565433 DOI: 10.1016/J.Pnpbp.2016.08.010  1
2016 Tyrer AE, Levitan RD, Houle S, Wilson AA, Nobrega JN, Rusjan PM, Meyer JH. Serotonin transporter binding is reduced in seasonal affective disorder following light therapy. Acta Psychiatrica Scandinavica. PMID 27553523 DOI: 10.1111/Acps.12632  1
2016 Tyrer AE, Levitan RD, Houle S, Wilson AA, Nobrega JN, Meyer JH. Increased Seasonal Variation in Serotonin Transporter Binding in Seasonal Affective Disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27087270 DOI: 10.1038/Npp.2016.54  1
2016 Hamani C, Nobrega JN. Reply to: Deep Brain Stimulation for Depression: Is It a Gray or White "Matter"? Biological Psychiatry. PMID 26987629 DOI: 10.1016/J.Biopsych.2016.01.007  1
2016 Reznikov R, Binko M, Nobrega JN, Hamani C. Deep Brain Stimulation in Animal Models of Fear, Anxiety, and Posttraumatic Stress Disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26932819 DOI: 10.1038/Npp.2016.34  1
2016 Nona CN, Lam M, Nobrega JN. Localized brain differences in Arc expression between mice showing low vs. high propensity to ethanol sensitization. Pharmacology, Biochemistry, and Behavior. 142: 15-22. PMID 26708208 DOI: 10.1016/J.Pbb.2015.12.006  1
2016 Sander SE, Diwan M, Raymond R, Nobrega JN, Richter A. Lower KV7.5 Potassium Channel Subunit Expression in an Animal Model of Paroxysmal Dystonia. Cns & Neurological Disorders Drug Targets. 15: 95-101. PMID 26553166 DOI: 10.2174/1871527315666151110124136  1
2016 Nona CN, Lam M, Nobrega JN. Localized brain differences in Arc expression between mice showing low vs. high propensity to ethanol sensitization Pharmacology Biochemistry and Behavior. 142: 15-22. DOI: 10.1016/j.pbb.2015.12.006  1
2015 Bambico FR, Duranti A, Nobrega JN, Gobbi G. The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26747370 DOI: 10.1016/J.Euroneuro.2015.12.027  1
2015 Bambico FR, Bregman T, Diwan M, Li J, Darvish-Ghane S, Li Z, Laver B, Amorim BO, Covolan L, Nobrega JN, Hamani C. Neuroplasticity-dependent and -independent mechanisms of chronic deep brain stimulation in stressed rats. Translational Psychiatry. 5: e674. PMID 26529427 DOI: 10.1038/Tp.2015.166  1
2015 Chakravarty MM, Hamani C, Martinez-Canabal A, Ellegood J, Laliberté C, Nobrega JN, Sankar T, Lozano AM, Frankland PW, Lerch JP. Deep brain stimulation of the ventromedial prefrontal cortex causes reorganization of neuronal processes and vasculature. Neuroimage. 125: 422-427. PMID 26525655 DOI: 10.1016/J.Neuroimage.2015.10.049  1
2015 Shen MY, Perreault ML, Bambico FR, Jones-Tabah J, Cheung M, Fan T, Nobrega JN, George SR. Rapid anti-depressant and anxiolytic actions following dopamine D1-D2 receptor heteromer inactivation. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26431907 DOI: 10.1016/J.Euroneuro.2015.09.004  1
2015 Nona CN, Bermejo MK, Ramsey AJ, Nobrega JN. Changes in dendritic spine density in the nucleus accumbens do not underlie ethanol sensitization. Synapse (New York, N.Y.). 69: 607-10. PMID 26340045 DOI: 10.1002/Syn.21862  1
2015 Amorim BO, Covolan L, Ferreira E, Brito JG, Nunes DP, de Morais DG, Nobrega JN, Rodrigues AM, deAlmeida AC, Hamani C. Deep brain stimulation induces antiapoptotic and anti-inflammatory effects in epileptic rats. Journal of Neuroinflammation. 12: 162. PMID 26337974 DOI: 10.1186/S12974-015-0384-7  1
2015 Winter C, Bregman T, Voget M, Raymond R, Hadar R, Nobrega JN, Hamani C. Acute high frequency stimulation of the prefrontal cortex or nucleus accumbens does not increase hippocampal neurogenesis in rats. Journal of Psychiatric Research. 68: 27-9. PMID 26228396 DOI: 10.1016/J.Jpsychires.2015.05.012  1
2015 Visanji NP, Kamali Sarvestani I, Creed MC, Shams Shoaei Z, Nobrega JN, Hamani C, Hazrati LN. Deep brain stimulation of the subthalamic nucleus preferentially alters the translational profile of striatopallidal neurons in an animal model of Parkinson's disease. Frontiers in Cellular Neuroscience. 9: 221. PMID 26106299 DOI: 10.3389/Fncel.2015.00221  1
2015 Harrison SJ, Tyrer AE, Levitan RD, Xu X, Houle S, Wilson AA, Nobrega JN, Rusjan PM, Meyer JH. Light therapy and serotonin transporter binding in the anterior cingulate and prefrontal cortex. Acta Psychiatrica Scandinavica. PMID 25891484 DOI: 10.1111/Acps.12424  1
2015 Insel N, Pilkiw M, Nobrega JN, Hutchison WD, Takehara-Nishiuchi K, Hamani C. Chronic deep brain stimulation of the rat ventral medial prefrontal cortex disrupts hippocampal-prefrontal coherence. Experimental Neurology. 269: 1-7. PMID 25842268 DOI: 10.1016/J.Expneurol.2015.03.023  1
2015 Bregman T, Reznikov R, Diwan M, Raymond R, Butson CR, Nobrega JN, Hamani C. Antidepressant-like Effects of Medial Forebrain Bundle Deep Brain Stimulation in Rats are not Associated With Accumbens Dopamine Release. Brain Stimulation. 8: 708-13. PMID 25835354 DOI: 10.1016/J.Brs.2015.02.007  1
2015 Lister J, Fletcher PJ, Nobrega JN, Remington G. Behavioral effects of food-derived opioid-like peptides in rodents: Implications for schizophrenia? Pharmacology, Biochemistry, and Behavior. 134: 70-78. PMID 25661529 DOI: 10.1016/J.Pbb.2015.01.020  1
2015 Reznikov R, Diwan M, Nobrega JN, Hamani C. Towards a better preclinical model of PTSD: characterizing animals with weak extinction, maladaptive stress responses and low plasma corticosterone. Journal of Psychiatric Research. 61: 158-65. PMID 25575638 DOI: 10.1016/J.Jpsychires.2014.12.017  1
2015 McCormick PN, Fletcher PJ, Wilson VS, Browne JD, Nobrega JN, Remington GJ. Low dose pramipexole causes D3 receptor-independent reduction of locomotion and responding for a conditioned reinforcer. Neuropharmacology. 89: 225-31. PMID 25283483 DOI: 10.1016/J.Neuropharm.2014.09.026  1
2015 Nona CN, Creed MC, Hamani C, Nobrega JN. Effects of high-frequency stimulation of the nucleus accumbens on the development and expression of ethanol sensitization in mice. Behavioural Pharmacology. 26: 184-92. PMID 24642732 DOI: 10.1097/Fbp.0000000000000033  1
2015 Tyrer AE, Levitan RD, Houle S, Wilson AA, Nobrega JN, Meyer JH. P.1.i.048 Seasonal variation in serotonin transporter binding in seasonal affective disorder and health: a [11C]DASB positron emission tomography study European Neuropsychopharmacology. 25. DOI: 10.1016/S0924-977X(15)30406-5  1
2014 Su P, Li S, Chen S, Lipina TV, Wang M, Lai TK, Lee FH, Zhang H, Zhai D, Ferguson SS, Nobrega JN, Wong AH, Roder JC, Fletcher PJ, Liu F. A dopamine D2 receptor-DISC1 protein complex may contribute to antipsychotic-like effects. Neuron. 84: 1302-16. PMID 25433637 DOI: 10.1016/J.Neuron.2014.11.007  1
2014 Miranda MF, Hamani C, de Almeida AC, Amorim BO, Macedo CE, Fernandes MJ, Nobrega JN, Aarão MC, Madureira AP, Rodrigues AM, Andersen ML, Tufik S, Mello LE, Covolan L. Role of adenosine in the antiepileptic effects of deep brain stimulation. Frontiers in Cellular Neuroscience. 8: 312. PMID 25324724 DOI: 10.3389/Fncel.2014.00312  1
2014 Lobo DS, Aleksandrova L, Knight J, Casey DM, El-Guebaly N, Nobrega JN, Kennedy JL. Addiction-related genes in gambling disorders: new insights from parallel human and pre-clinical models. Molecular Psychiatry. PMID 25266122 DOI: 10.1038/Mp.2014.113  1
2014 Hamani C, Amorim BO, Wheeler AL, Diwan M, Driesslein K, Covolan L, Butson CR, Nobrega JN. Deep brain stimulation in rats: different targets induce similar antidepressant-like effects but influence different circuits. Neurobiology of Disease. 71: 205-14. PMID 25131446 DOI: 10.1016/J.Nbd.2014.08.007  1
2014 Covolan L, de Almeida AC, Amorim B, Cavarsan C, Miranda MF, Aarão MC, Madureira AP, Rodrigues AM, Nobrega JN, Mello LE, Hamani C. Effects of anterior thalamic nucleus deep brain stimulation in chronic epileptic rats. Plos One. 9: e97618. PMID 24892420 DOI: 10.1371/Journal.Pone.0097618  1
2014 Lister J, Nobrega JN, Fletcher PJ, Remington G. Oxidative stress and the antipsychotic-induced vacuous chewing movement model of tardive dyskinesia: evidence for antioxidant-based prevention strategies. Psychopharmacology. 231: 2237-49. PMID 24752659 DOI: 10.1007/S00213-014-3582-6  1
2014 Laver B, Diwan M, Nobrega JN, Hamani C. Augmentative therapies do not potentiate the antidepressant-like effects of deep brain stimulation in rats. Journal of Affective Disorders. 161: 87-90. PMID 24751313 DOI: 10.1016/J.Jad.2014.03.007  1
2014 Bregman T, Diwan M, Nobrega JN, Hamani C. Supraorbital stimulation does not induce an antidepressant-like response in rats. Brain Stimulation. 7: 301-3. PMID 24629830 DOI: 10.1016/J.Brs.2013.11.002  1
2014 Leggio GM, Camillieri G, Platania CB, Castorina A, Marrazzo G, Torrisi SA, Nona CN, D'Agata V, Nobrega J, Stark H, Bucolo C, Le Foll B, Drago F, Salomone S. Dopamine D3 receptor is necessary for ethanol consumption: an approach with buspirone. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2017-28. PMID 24584330 DOI: 10.1038/Npp.2014.51  1
2014 Wheeler AL, Creed MC, Voineskos AN, Nobrega JN. Changes in brain functional connectivity after chronic haloperidol in rats: a network analysis. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 1129-38. PMID 24524273 DOI: 10.1017/S1461145714000042  1
2014 Nona CN, Li R, Nobrega JN. Altered NMDA receptor subunit gene expression in brains of mice showing high vs. low sensitization to ethanol. Behavioural Brain Research. 260: 58-66. PMID 24315834 DOI: 10.1016/J.Bbr.2013.11.037  1
2014 Mahar I, Bambico FR, Mechawar N, Nobrega JN. Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects. Neuroscience and Biobehavioral Reviews. 38: 173-92. PMID 24300695 DOI: 10.1016/J.Neubiorev.2013.11.009  1
2014 Hahn MK, Chintoh A, Remington G, Teo C, Mann S, Arenovich T, Fletcher P, Lam L, Nobrega J, Guenette M, Cohn T, Giacca A. Effects of intracerebroventricular (ICV) olanzapine on insulin sensitivity and secretion in vivo: an animal model. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 448-58. PMID 24001874 DOI: 10.1016/J.Euroneuro.2013.07.011  1
2014 Platania CB, Leggio GM, Camillieri G, Castorina A, Torrisi SA, Nona CN, D'Agata V, Nobrega J, Foll BL, Drago F. P.1.006 Molecular basis of alcohol intake: role of D3 dopaminergic receptor European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70009-4  1
2013 Dubiela FP, Queiroz CM, Moreira KD, Nobrega JN, Sita LV, Tufik S, Hipolide DC. AMPA receptors mediate passive avoidance deficits induced by sleep deprivation. Behavioural Brain Research. 257: 189-96. PMID 24079994 DOI: 10.1016/J.Bbr.2013.09.037  1
2013 Hamani C, Nobrega JN. Deep brain stimulation and memory. Expert Review of Medical Devices. 10: 429-31. PMID 23895068 DOI: 10.1586/17434440.2013.811838  1
2013 Sadovski O, Hicks JW, Parkes J, Raymond R, Nobrega J, Houle S, Cipriano M, Fowler CJ, Vasdev N, Wilson AA. Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase. Bioorganic & Medicinal Chemistry. 21: 4351-7. PMID 23712084 DOI: 10.1016/J.Bmc.2013.04.077  1
2013 Aleksandrova LR, Creed MC, Fletcher PJ, Lobo DS, Hamani C, Nobrega JN. Deep brain stimulation of the subthalamic nucleus increases premature responding in a rat gambling task. Behavioural Brain Research. 245: 76-82. PMID 23434606 DOI: 10.1016/J.Bbr.2013.02.011  1
2013 Creed MC, Nobrega JN. The role of serotonin in the antidyskinetic effects of deep brain stimulation: focus on antipsychotic-induced motor symptoms. Reviews in the Neurosciences. 24: 153-66. PMID 23399586 DOI: 10.1515/Revneuro-2012-0083  1
2013 Nona CN, Guirguis S, Nobrega JN. Susceptibility to ethanol sensitization is differentially associated with changes in pCREB, trkB and BDNF mRNA expression in the mouse brain. Behavioural Brain Research. 242: 25-33. PMID 23291223 DOI: 10.1016/J.Bbr.2012.12.035  1
2013 Pushparaj A, Hamani C, Yu W, Shin DS, Kang B, Nobrega JN, Le Foll B. Electrical stimulation of the insular region attenuates nicotine-taking and nicotine-seeking behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 690-8. PMID 23249816 DOI: 10.1038/Npp.2012.235  1
2013 Mann S, Chintoh A, Giacca A, Fletcher P, Nobrega J, Hahn M, Remington G. Chronic olanzapine administration in rats: effect of route of administration on weight, food intake and body composition. Pharmacology, Biochemistry, and Behavior. 103: 717-22. PMID 23234835 DOI: 10.1016/J.Pbb.2012.12.002  1
2013 Burton CL, Rizos Z, Diwan M, Nobrega JN, Fletcher PJ. Antagonizing 5-HTâ‚‚A receptors with M100907 and stimulating 5-HTâ‚‚C receptors with Ro60-0175 blocks cocaine-induced locomotion and zif268 mRNA expression in Sprague-Dawley rats. Behavioural Brain Research. 240: 171-81. PMID 23201361 DOI: 10.1016/J.Bbr.2012.11.030  1
2013 Creed MC, Nobrega JN. Neurobiological basis of dyskinetic effects induced by antipsychotics: the contribution of animal models. Current Medicinal Chemistry. 20: 389-96. PMID 23157631 DOI: 10.2174/0929867311320030010  1
2013 Creed MC, Hamani C, Nobrega JN. Effects of repeated deep brain stimulation on depressive- and anxiety-like behavior in rats: comparing entopeduncular and subthalamic nuclei. Brain Stimulation. 6: 506-14. PMID 23088853 DOI: 10.1016/J.Brs.2012.09.012  1
2013 Pinho N, Moreira KM, Hipolide DC, Sinigaglia-Coimbra R, Ferreira TL, Nobrega JN, Tufik S, Oliveira MG. Sleep deprivation alters phosphorylated CREB levels in the amygdala: relationship with performance in a fear conditioning task. Behavioural Brain Research. 236: 221-4. PMID 22974552 DOI: 10.1016/J.Bbr.2012.08.043  1
2012 Hamani C, Giacobbe P, Diwan M, Balbino ES, Tong J, Bridgman A, Lipsman N, Lozano AM, Kennedy SH, Nobrega JN. Monoamine oxidase inhibitors potentiate the effects of deep brain stimulation. The American Journal of Psychiatry. 169: 1320-1. PMID 23212066 DOI: 10.1176/Appi.Ajp.2012.12060754  1
2012 Creed MC, Hamani C, Bridgman A, Fletcher PJ, Nobrega JN. Contribution of decreased serotonin release to the antidyskinetic effects of deep brain stimulation in a rodent model of tardive dyskinesia: comparison of the subthalamic and entopeduncular nuclei. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9574-81. PMID 22787043 DOI: 10.1523/Jneurosci.1196-12.2012  1
2012 Hamani C, Nobrega JN. Preclinical studies modeling deep brain stimulation for depression. Biological Psychiatry. 72: 916-23. PMID 22748616 DOI: 10.1016/J.Biopsych.2012.05.024  1
2012 Creed MC, Hamani C, Nobrega JN. Early gene mapping after deep brain stimulation in a rat model of tardive dyskinesia: comparison with transient local inactivation. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 22: 506-17. PMID 22153973 DOI: 10.1016/J.Euroneuro.2011.11.004  1
2012 Hamani C, Machado DC, Hipólide DC, Dubiela FP, Suchecki D, Macedo CE, Tescarollo F, Martins U, Covolan L, Nobrega JN. Deep brain stimulation reverses anhedonic-like behavior in a chronic model of depression: role of serotonin and brain derived neurotrophic factor. Biological Psychiatry. 71: 30-5. PMID 22000731 DOI: 10.1016/J.Biopsych.2011.08.025  1
2012 Scott BW, Nobrega JN, Hamani C. Deep brain stimulation in animal models of depression Deep Brain Stimulation: a New Frontier in Psychiatry. 103-112. DOI: 10.1007/978-3-642-30991-5_11  1
2011 Remington G, Mann S, McCormick P, Nobrega JN, Hahn M, Natesan S. Modeling chronic olanzapine exposure using osmotic minipumps: pharmacological limitations. Pharmacology, Biochemistry, and Behavior. 100: 86-9. PMID 21839766 DOI: 10.1016/J.Pbb.2011.07.019  1
2011 Troncone LR, Ravelli KG, Magnoli FC, Lebrun I, Hipolide DC, Raymond R, Nobrega JN. Regional brain c-fos activation associated with penile erection and other symptoms induced by the spider toxin Tx2-6. Toxicon : Official Journal of the International Society On Toxinology. 58: 202-8. PMID 21684302 DOI: 10.1016/J.Toxicon.2011.05.019  1
2011 Creed-Carson M, Oraha A, Nobrega JN. Effects of 5-HT(2A) and 5-HT(2C) receptor antagonists on acute and chronic dyskinetic effects induced by haloperidol in rats. Behavioural Brain Research. 219: 273-9. PMID 21262266 DOI: 10.1016/J.Bbr.2011.01.025  0.01
2011 Araujo JA, Nobrega JN, Raymond R, Milgram NW. Aged dogs demonstrate both increased sensitivity to scopolamine impairment and decreased muscarinic receptor density. Pharmacology, Biochemistry, and Behavior. 98: 203-9. PMID 21238475 DOI: 10.1016/J.Pbb.2011.01.005  1
2011 Natesan S, Reckless GE, Barlow KB, Nobrega JN, Kapur S. Partial agonists in schizophrenia--why some work and others do not: insights from preclinical animal models. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 1165-78. PMID 21087552 DOI: 10.1017/S1461145710001343  1
2011 Brown ZJ, Nobrega JN, Erb S. Central injections of noradrenaline induce reinstatement of cocaine seeking and increase c-fos mRNA expression in the extended amygdala. Behavioural Brain Research. 217: 472-6. PMID 20933023 DOI: 10.1016/J.Bbr.2010.09.025  1
2011 Dubiela FP, Messias MF, Moreira KD, Zanlorenci LH, Grassl C, Filho RF, Nobrega JN, Tufik S, Hipólide DC. Reciprocal interactions between MK-801, sleep deprivation and recovery in modulating rat behaviour. Behavioural Brain Research. 216: 180-5. PMID 20678528 DOI: 10.1016/J.Bbr.2010.07.031  1
2011 Leggio GM, Micale V, Le Foll B, Mazzola C, Nobrega JN, Drago F. Dopamine D3 receptor knock-out mice exhibit increased behavioral sensitivity to the anxiolytic drug diazepam. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 21: 325-32. PMID 20627473 DOI: 10.1016/J.Euroneuro.2010.05.006  1
2011 Creed M, Hamani C, Nobrega JN. Deep brain stimulation of the subthalamic or entopeduncular nucleus attenuates vacuous chewing movements in a rodent model of tardive dyskinesia. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 21: 393-400. PMID 20624675 DOI: 10.1016/J.Euroneuro.2010.06.012  1
2011 Hamani C, Diwan M, Raymond R, Nobrega JN, MacEdo CE, Brandão ML, Shumake J, Gonzalez-Lima F, Lozano AM, Fletcher PJ. Reply to: Electrical brain stimulation in depression: Which target(s)? Biological Psychiatry. 69: e7-e8. DOI: 10.1016/J.Biopsych.2010.10.012  1
2010 Pei L, Li S, Wang M, Diwan M, Anisman H, Fletcher PJ, Nobrega JN, Liu F. Uncoupling the dopamine D1-D2 receptor complex exerts antidepressant-like effects. Nature Medicine. 16: 1393-5. PMID 21113156 DOI: 10.1038/Nm.2263  1
2010 Hamani C, Nóbrega JN. Deep brain stimulation in clinical trials and animal models of depression. The European Journal of Neuroscience. 32: 1109-17. PMID 21039950 DOI: 10.1111/J.1460-9568.2010.07414.X  1
2010 Sander SE, Raymond R, Nobrega JN, Richter A. Autoradiographic and pharmacological studies on the role of dopamine D3 receptors in genetically dystonic (dt(sz)) hamsters. Pharmacology, Biochemistry, and Behavior. 96: 136-40. PMID 20451545 DOI: 10.1016/J.Pbb.2010.04.021  1
2010 McCormick PN, Kapur S, Graff-Guerrero A, Raymond R, Nobrega JN, Wilson AA. The antipsychotics olanzapine, risperidone, clozapine, and haloperidol are D2-selective ex vivo but not in vitro. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1826-35. PMID 20410873 DOI: 10.1038/Npp.2010.50  1
2010 Hamani C, Diwan M, Isabella S, Lozano AM, Nobrega JN. Effects of different stimulation parameters on the antidepressant-like response of medial prefrontal cortex deep brain stimulation in rats. Journal of Psychiatric Research. 44: 683-7. PMID 20096858 DOI: 10.1016/J.Jpsychires.2009.12.010  1
2010 Burton CL, Nobrega JN, Fletcher PJ. The effects of adolescent methylphenidate self-administration on responding for a conditioned reward, amphetamine-induced locomotor activity, and neuronal activation. Psychopharmacology. 208: 455-68. PMID 20020108 DOI: 10.1007/S00213-009-1745-7  1
2010 Dubiela FP, Oliveira MG, Moreira KM, Nobrega JN, Tufik S, Hipólide DC. Inverse benzodiazepine agonist beta-CCM does not reverse learning deficit induced by sleep deprivation. Neuroscience Letters. 469: 169-73. PMID 19962429 DOI: 10.1016/J.Neulet.2009.11.070  1
2010 Hamani C, Diwan M, Macedo CE, Brandão ML, Shumake J, Gonzalez-Lima F, Raymond R, Lozano AM, Fletcher PJ, Nobrega JN. Antidepressant-like effects of medial prefrontal cortex deep brain stimulation in rats. Biological Psychiatry. 67: 117-24. PMID 19819426 DOI: 10.1016/J.Biopsych.2009.08.025  1
2009 Harrison SJ, Nobrega JN. A functional role for the dopamine D3 receptor in the induction and expression of behavioural sensitization to ethanol in mice. Psychopharmacology. 207: 47-56. PMID 19662386 DOI: 10.1007/S00213-009-1629-X  1
2009 Rabiner EA, Slifstein M, Nobrega J, Plisson C, Huiban M, Raymond R, Diwan M, Wilson AA, McCormick P, Gentile G, Gunn RN, Laruelle MA. In vivo quantification of regional dopamine-D3 receptor binding potential of (+)-PHNO: Studies in non-human primates and transgenic mice Synapse. 63: 782-793. PMID 19489048 DOI: 10.1002/Syn.20658  1
2009 Sander SE, Richter F, Raymond R, Diwan M, Lange N, Nobrega JN, Richter A. Pharmacological and autoradiographic studies on the pathophysiological role of GABA(B) receptors in the dystonic hamster: pronounced antidystonic effects of baclofen after striatal injections. Neuroscience. 162: 423-30. PMID 19427369 DOI: 10.1016/J.Neuroscience.2009.05.007  1
2009 Chintoh AF, Mann SW, Lam L, Giacca A, Fletcher P, Nobrega J, Remington G. Insulin resistance and secretion in vivo: effects of different antipsychotics in an animal model. Schizophrenia Research. 108: 127-33. PMID 19157785 DOI: 10.1016/J.Schres.2008.12.012  1
2009 Palma BD, Nobrega JN, Gomes VL, Esumi LA, Seabra ML, Tufik S, Hipolide DC. Prostaglandin involvement in hyperthermia induced by sleep deprivation: a pharmacological and autoradiographic study. Life Sciences. 84: 278-81. PMID 19135460 DOI: 10.1016/J.Lfs.2008.12.009  1
2009 Harrison SJ, Nobrega JN. Differential susceptibility to ethanol and amphetamine sensitization in dopamine D3 receptor-deficient mice. Psychopharmacology. 204: 49-59. PMID 19096829 DOI: 10.1007/S00213-008-1435-X  1
2009 Stein EJ, da Silveira Filho NG, Machado DC, Hipólide DC, Barlow K, Nobrega JN. Chronic mild stress induces widespread decreases in thyroid hormone alpha1 receptor mRNA levels in brain--reversal by imipramine. Psychoneuroendocrinology. 34: 281-6. PMID 18930353 DOI: 10.1016/J.Psyneuen.2008.09.005  1
2008 Chintoh AF, Mann SW, Lam L, Lam C, Cohn TA, Fletcher PJ, Nobrega JN, Giacca A, Remington G. Insulin resistance and decreased glucose-stimulated insulin secretion after acute olanzapine administration. Journal of Clinical Psychopharmacology. 28: 494-9. PMID 18794643 DOI: 10.1097/Jcp.0B013E318184B4C5  1
2008 Natesan S, Reckless GE, Barlow KB, Nobrega JN, Kapur S. Amisulpride the 'atypical' atypical antipsychotic--comparison to haloperidol, risperidone and clozapine. Schizophrenia Research. 105: 224-35. PMID 18710798 DOI: 10.1016/J.Schres.2008.07.005  1
2008 Natesan S, Reckless GE, Barlow KBL, Odontiadis J, Nobrega JN, Baker GB, George SR, Mamo D, Kapur S. The antipsychotic potential of l-stepholidine - A naturally occurring dopamine receptor D1 agonist and D2 antagonist Psychopharmacology. 199: 275-289. PMID 18521575 DOI: 10.1007/S00213-008-1172-1  1
2008 Samaha AN, Reckless GE, Seeman P, Diwan M, Nobrega JN, Kapur S. Less is more: antipsychotic drug effects are greater with transient rather than continuous delivery. Biological Psychiatry. 64: 145-52. PMID 18295747 DOI: 10.1016/J.Biopsych.2008.01.010  1
2007 Vasdev N, Seeman P, Garcia A, Stableford WT, Nobrega JN, Houle S, Wilson AA. Syntheses and in vitro evaluation of fluorinated naphthoxazines as dopamine D2/D3 receptor agonists: radiosynthesis, ex vivo biodistribution and autoradiography of [(18)F]F-PHNO. Nuclear Medicine and Biology. 34: 195-203. PMID 17307127 DOI: 10.1016/J.Nucmedbio.2006.11.001  1
2007 Nascimento DC, Andersen ML, Hipólide DC, Nobrega JN, Tufik S. Pain hypersensitivity induced by paradoxical sleep deprivation is not due to altered binding to brain mu-opioid receptors. Behavioural Brain Research. 178: 216-20. PMID 17239968 DOI: 10.1016/J.Bbr.2006.12.016  1
2007 Schirmer M, Nobrega JN, Harrison SJ, Löscher W. Alterations in dopamine D3 receptors in the circling (ci3) rat mutant Neuroscience. 144: 1462-1469. PMID 17187934 DOI: 10.1016/J.Neuroscience.2006.11.022  1
2007 Natesan S, Reckless GE, Barlow KB, Nobrega JN, Kapur S. Evaluation of N-desmethylclozapine as a potential antipsychotic--preclinical studies. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1540-9. PMID 17164815 DOI: 10.1038/Sj.Npp.1301279  1
2007 Featherstone RE, Rizos Z, Nobrega JN, Kapur S, Fletcher PJ. Gestational methylazoxymethanol acetate treatment impairs select cognitive functions: parallels to schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 483-92. PMID 17035930 DOI: 10.1038/Sj.Npp.1301223  1
2007 Nascimento DC, Andersen ML, Hipólide DC, Nobrega JN, Tufík S. L0009 Pain hypersensitivity induced by paradoxical sleep deprivation is not due to altered binding to brain μ-opioid receptors Sleep Medicine. 8. DOI: 10.1016/S1389-9457(07)70379-9  1
2006 de Souza FG, Rodrigues MD, Tufik S, Nobrega JN, D'Almeida V. Acute stressor-selective effects on homocysteine metabolism and oxidative stress parameters in female rats. Pharmacology, Biochemistry, and Behavior. 85: 400-7. PMID 17056102 DOI: 10.1016/J.Pbb.2006.09.008  1
2006 Martins PJ, D'Almeida V, Nobrega JN, Tufik S. A reassessment of the hyperphagia/weight-loss paradox during sleep deprivation. Sleep. 29: 1233-8. PMID 17040011 DOI: 10.1093/Sleep/29.9.1233  1
2006 Hamann M, Raymond R, Varughesi S, Nobrega JN, Richter A. Acetylcholine receptor binding and cholinergic interneuron density are unaltered in a genetic animal model of primary paroxysmal dystonia. Brain Research. 1099: 176-82. PMID 16764832 DOI: 10.1016/J.Brainres.2006.04.100  1
2006 Natesan S, Svensson KA, Reckless GE, Nobrega JN, Barlow KB, Johansson AM, Kapur S. The dopamine stabilizers (S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine [(-)-OSU6162] and 4-(3-methanesulfonylphenyl)-1-propyl-piperidine (ACR16) show high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor side effects in the rat. The Journal of Pharmacology and Experimental Therapeutics. 318: 810-8. PMID 16648369 DOI: 10.1124/Jpet.106.102905  1
2006 Ejchel-Cohen TF, Wood GE, Wang JF, Barlow K, Nobrega JN, S McEwen B, Trevor Young L. Chronic restraint stress decreases the expression of glutathione S-transferase pi2 in the mouse hippocampus. Brain Research. 1090: 156-62. PMID 16643866 DOI: 10.1016/J.Brainres.2006.03.062  1
2006 Schenberg EE, Ferreira TL, Figueredo LZP, Hipólide DC, Nobrega JN, Oliveira MGM. Fear conditioning performance and NMDA receptor subtypes: NR2A differential expression in the striatum Brain Research Bulletin. 69: 440-446. PMID 16624675 DOI: 10.1016/J.Brainresbull.2006.02.010  1
2006 Natesan S, Reckless GE, Nobrega JN, Fletcher PJ, Kapur S. Dissociation between in vivo occupancy and functional antagonism of dopamine D2 receptors: comparing aripiprazole to other antipsychotics in animal models. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1854-63. PMID 16319908 DOI: 10.1038/Sj.Npp.1300983  1
2005 Natesan S, Vanderspek S, Nobrega JN, McClelland RA, Kapur S. Contrasting loxapine to its isomer isoloxapine--the critical role of in vivo D2 blockade in determining atypicality. Schizophrenia Research. 77: 189-99. PMID 15925489 DOI: 10.1016/J.Schres.2005.03.009  1
2005 D'Almeida V, Hipólide DC, Raymond R, Barlow KB, Parkes JH, Pedrazzoli M, Tufik S, Nobrega JN. Opposite effects of sleep rebound on orexin OX1 and OX2 receptor expression in rat brain. Brain Research. Molecular Brain Research. 136: 148-57. PMID 15893599 DOI: 10.1016/J.Molbrainres.2005.02.002  1
2005 Andersen ML, Papale LA, Hipólide DC, Nobrega JN, Tufik S. Involvement of dopamine receptors in cocaine-induced genital reflexes after paradoxical sleep deprivation. Behavioural Brain Research. 160: 44-50. PMID 15836899 DOI: 10.1016/J.Bbr.2004.11.016  1
2005 Hellemans KG, Nobrega JN, Olmstead MC. Early environmental experience alters baseline and ethanol-induced cognitive impulsivity: relationship to forebrain 5-HT1A receptor binding. Behavioural Brain Research. 159: 207-20. PMID 15817184 DOI: 10.1016/J.Bbr.2004.10.018  1
2005 Dubiela FP, Oliveira MG, Moreira KM, Nobrega JN, Tufik S, Hipólide DC. Learning deficits induced by sleep deprivation and recovery are not associated with altered [(3)H]muscimol and [(3)H]flunitrazepam binding. Brain Research. 1037: 157-63. PMID 15777764 DOI: 10.1016/J.Brainres.2005.01.005  1
2005 Turrone P, Remington G, Kapur S, Nobrega JN. Continuous but not intermittent olanzapine infusion induces vacuous chewing movements in rats. Biological Psychiatry. 57: 406-11. PMID 15705357 DOI: 10.1016/J.Biopsych.2004.10.023  1
2005 Hipólide DC, Moreira KM, Barlow KB, Wilson AA, Nobrega JN, Tufik S. Distinct effects of sleep deprivation on binding to norepinephrine and serotonin transporters in rat brain. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 297-303. PMID 15694238 DOI: 10.1016/J.Pnpbp.2004.11.015  1
2004 Mirecki A, Fitzmaurice P, Ang L, Kalasinsky KS, Peretti FJ, Aiken SS, Wickham DJ, Sherwin A, Nobrega JN, Forman HJ, Kish SJ. Brain antioxidant systems in human methamphetamine users. Journal of Neurochemistry. 89: 1396-408. PMID 15189342 DOI: 10.1111/J.1471-4159.2004.02434.X  1
2004 Setnik B, Nobrega JN. Long-chain acyl-CoenzymeA synthetase-2 mRNA: increased cerebral cortex expression in an animal model of depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 28: 577-82. PMID 15093965 DOI: 10.1016/J.Pnpbp.2004.01.014  0.01
2004 Setnik B, de Souza FG, d'Almeida V, Nobrega JN. Increased homocysteine levels associated with sex and stress in the learned helplessness model of depression. Pharmacology, Biochemistry, and Behavior. 77: 155-61. PMID 14724053 DOI: 10.1016/J.Pbb.2003.10.006  1
2004 Verhoeff NP, Wilson AA, Nobrega J, Westaway D, George-Hyslop PS, Hussey D, Takeshita S, Trop L, Singh K, Kung HF, Kung M, Houle S. O3-03-07 [11C]SB-13 PET: a valid alternative for β-amyloid imaging in vivo? Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80197-0  1
2003 Turrone P, Remington G, Kapur S, Nobrega JN. Differential effects of within-day continuous vs. transient dopamine D2 receptor occupancy in the development of vacuous chewing movements (VCMs) in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1433-9. PMID 12838271 DOI: 10.1038/Sj.Npp.1300233  1
2003 Moreira KM, Hipólide DC, Nobrega JN, Bueno OF, Tufik S, Oliveira MG. Deficits in avoidance responding after paradoxical sleep deprivation are not associated with altered [3H]pirenzepine binding to M1 muscarinic receptors in rat brain. Brain Research. 977: 31-7. PMID 12788510 DOI: 10.1016/S0006-8993(03)02688-X  1
2003 Wilson AA, Johnson DP, Mozley D, Hussey D, Ginovart N, Nobrega J, Garcia A, Meyer J, Houle S. Synthesis and in vivo evaluation of novel radiotracers for the in vivo imaging of the norepinephrine transporter Nuclear Medicine and Biology. 30: 85-92. PMID 12623106 DOI: 10.1016/S0969-8051(02)00420-1  1
2003 Kapur S, VanderSpek SC, Brownlee BA, Nobrega JN. Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy. The Journal of Pharmacology and Experimental Therapeutics. 305: 625-31. PMID 12606608 DOI: 10.1124/Jpet.102.046987  1
2003 Turrone P, Remington G, Kapur S, Nobrega JN. The relationship between dopamine D2 receptor occupancy and the vacuous chewing movement syndrome in rats. Psychopharmacology. 165: 166-71. PMID 12417967 DOI: 10.1007/S00213-002-1259-Z  1
2003 VanderSpek SC, Brownlee BA, Nobrega J, McClelland R, Seeman P, Kapur S. Converting a typical antipsychotic into an atypical one — The critical role of D2 Schizophrenia Research. 60: 117-118. DOI: 10.1016/S0920-9964(03)80876-9  1
2002 Wunderlich GR, Raymond R, DeSousa NJ, Nobrega JN, Vaccarino FJ. Decreased CCK(B) receptor binding in rat amygdala in animals demonstrating greater anxiety-like behavior. Psychopharmacology. 164: 193-9. PMID 12404082 DOI: 10.1007/S00213-002-1181-4  1
2002 Nobrega JN, Raymond R, Barlow K, Hamann M, Richter A. Changes in AMPA receptor binding in an animal model of inborn paroxysmal dystonia. Experimental Neurology. 176: 371-6. PMID 12359179 DOI: 10.1006/Exnr.2002.7932  1
2002 Hipólide DC, D'Almeida V, Raymond R, Tufik S, Nobrega JN. Sleep deprivation does not affect indices of necrosis or apoptosis in rat brain. The International Journal of Neuroscience. 112: 155-66. PMID 12325404 DOI: 10.1080/00207450212022  1
2002 Quadros IM, Nobrega JN, Hipólide DC, de Lucca EM, Souza-Formigoni ML. Differential propensity to ethanol sensitization is not associated with altered binding to D1 receptors or dopamine transporters in mouse brain. Addiction Biology. 7: 291-9. PMID 12126488 DOI: 10.1080/13556210220139505  1
2002 Turrone P, Remington G, Nobrega JN. The vacuous chewing movement (VCM) model of tardive dyskinesia revisited: is there a relationship to dopamine D(2) receptor occupancy? Neuroscience and Biobehavioral Reviews. 26: 361-80. PMID 12034136 DOI: 10.1016/S0149-7634(02)00008-8  1
2002 Quadros IM, Hipólide DC, Frussa-Filho R, De Lucca EM, Nobrega JN, Souza-Formigoni ML. Resistance to ethanol sensitization is associated with increased NMDA receptor binding in specific brain areas. European Journal of Pharmacology. 442: 55-61. PMID 12020682 DOI: 10.1016/S0014-2999(02)01503-0  1
2002 Kapur S, McClelland RA, VanderSpek SC, Wadenberg ML, Baker G, Nobrega J, Zipursky RB, Seeman P. Increasing D2 affinity results in the loss of clozapine's atypical antipsychotic action. Neuroreport. 13: 831-5. PMID 11997696 DOI: 10.1097/00001756-200205070-00019  1
2002 De Oliveira AC, D'Almeida V, Hipólide DC, Nobrega JN, Tufik S. Sleep deprivation reduces total plasma homocysteine levels in rats Canadian Journal of Physiology and Pharmacology. 80: 193-197. PMID 11991229 DOI: 10.1139/Y02-018  1
2001 Kapur S, Barlow K, VanderSpek SC, Javanmard M, Nobrega JN. Drug-induced receptor occupancy: Substantial differences in measurements made in vivo vs ex vivo Psychopharmacology. 157: 168-171. PMID 11594441 DOI: 10.1007/S002130100790  1
2001 Vallbacka JJ, Nobrega JN, Sefton MV. Tissue engineering as a platform for controlled release of therapeutic agents: implantation of microencapsulated dopamine producing cells in the brains of rats. Journal of Controlled Release : Official Journal of the Controlled Release Society. 72: 93-100. PMID 11389988 DOI: 10.1016/S0168-3659(01)00265-6  0.01
2000 Yeomans JS, Takeuchi J, Baptista M, Flynn DD, Lepik K, Nobrega J, Fulton J, Ralph MR. Brain-stimulation reward thresholds raised by an antisense oligonucleotide for the M5 muscarinic receptor infused near dopamine cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8861-7. PMID 11102495 DOI: 10.1523/Jneurosci.20-23-08861.2000  1
2000 Barsoum SC, Kapur S, Nobrega J, Seeman P. 511. Significant differences between occupancy measured with radioligand vs. EEDQ Biological Psychiatry. 47. DOI: 10.1016/S0006-3223(00)00781-2  1
1998 Campioni EG, Nobrega JN, Sefton MV. HEMA/MMMA microcapsule implants in hemiparkinsonian rat brain: biocompatibility assessment using [3H]PK11195 as a marker for gliosis. Biomaterials. 19: 829-37. PMID 9663760 DOI: 10.1016/S0142-9612(97)00241-X  0.01
1998 Sasaki T, Kennedy JL, Nobrega JN. Regional brain changes in [3H]SCH 23390 binding to dopamine D1 receptors after long-term haloperidol treatment: Lack of correspondence with the development of vacuous chewing movements Behavioural Brain Research. 90: 125-132. PMID 9521545 DOI: 10.1016/S0166-4328(97)00092-2  1
1997 Seeman P, Guan HC, Nobrega J, Jiwa D, Markstein R, Balk JH, Picetti R, Borrelli E, Tol HHMV. Dopamine D2-like sites in schizophrenia, but not in Alzheimer's, Huntington's, or control brains, for [3H]benzquinoline. Synapse. 25: 137-146. PMID 9021894 DOI: 10.1002/(Sici)1098-2396(199702)25:2<137::Aid-Syn4>3.0.Co;2-D  1
1997 Sasaki T, Kennedy JL, Nobrega JN. Localized changes in GABA receptor-gated chloride channel in rat brain after long-term haloperidol: Relation to vacuous chewing movements Synapse. 25: 73-79. PMID 8987150 DOI: 10.1002/(Sici)1098-2396(199701)25:1<73::Aid-Syn9>3.0.Co;2-C  1
1996 Sasaki T, Kennedy JL, Nobrega JN. Autoradiographic mapping of μ opioid receptor changes in rat brain after long-term haloperidol treatment: Relationship to the development of vacuous chewing movements Psychopharmacology. 128: 97-104. PMID 8944412 DOI: 10.1007/S002130050115  1
1996 Schoots O, Yue KT, MacDonald JF, Hampson DR, Nobrega JN, Dixon LM, Van Tol HH. Cloning of a G protein-activated inwardly rectifying potassium channel from human cerebellum. Brain Research. Molecular Brain Research. 39: 23-30. PMID 8804710 DOI: 10.1016/0169-328X(95)00349-W  1
1995 Nobrega JN, Richter A, Burnham WM, Lôscher W. Alterations in the brain GABAA/benzodiazepine receptor-chloride ionophore complex in a genetic model of paroxysmal dystonia: a quantitative autoradiographic analysis. Neuroscience. 64: 229-39. PMID 7708208 DOI: 10.1016/0306-4522(94)00334-2  1
1995 Tai TC, Tompa J, Nobrega JN, Adamson SL. Changes in regional cytochrome oxidase activity in the fetal, newborn and adult ovine brainstem. Brain Research. Developmental Brain Research. 86: 7-15. PMID 7656434 DOI: 10.1016/0165-3806(95)00005-X  0.01
1994 Coscina DV, Feifel D, Nobrega JN, Currie PJ. Intraventricular but not intraparaventricular nucleus metergoline elicits feeding in satiated rats. The American Journal of Physiology. 266: R1562-7. PMID 8203633 DOI: 10.1152/Ajpregu.1994.266.5.R1562  1
1994 Wilson JM, Nobrega JN, Carroll ME, Niznik HB, Shannak K, Lac ST, Pristupa ZB, Dixon LM, Kish SJ. Heterogeneous subregional binding patterns of 3H-WIN 35,428 and 3H-GBR 12,935 are differentially regulated by chronic cocaine self-administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 2966-79. PMID 8182452 DOI: 10.1523/Jneurosci.14-05-02966.1994  1
1994 Joffe RT, Nobrega JN, Kish SJ, Calvo R, Dixon LM, Wilson JM, Morreale de Escobar G. Regional thyroid hormone levels in rat brain Psychoneuroendocrinology. 19: 773-777. PMID 7991764 DOI: 10.1016/0306-4530(94)90024-8  1
1993 Nobrega JN, Petrasek JS, Raymond R, Dixon LM, Burnham WM. Brain cytochrome oxidase activity after kindled seizures: a quantitative histochemical mapping study. Brain Research. 622: 113-8. PMID 8242351 DOI: 10.1016/0006-8993(93)90809-2  1
1993 Brooks WJ, Petit TL, Leboutillier JC, Nobrega JN, Jarvis MF. Differential effects of early chronic lead exposure on postnatal rat brain NDMA, PCP, and adenosine A1 receptors: An autoradiographic study Drug Development Research. 29: 40-47. DOI: 10.1002/Ddr.430290105  1
1992 Wilson JM, Nobrega JN, Corrigall W, Shannak K, Deck JHN, Kish SJ. Influence of chronic cocaine on monoamine neurotransmitters in human brain and animal model: Preliminary observations Annals of the New York Academy of Sciences. 654: 461-463. PMID 1632604 DOI: 10.1111/J.1749-6632.1992.Tb25999.X  1
1992 Nobrega JN, Saari MJ, Armstrong JN, Reed T. Neonatal 6-OHDA lesions and rearing in complex environments: regional effects on adult brain 14C-2-deoxyglucose uptake revealed by exposure to novel stimulation. Developmental Psychobiology. 25: 183-98. PMID 1618370 DOI: 10.1002/Dev.420250304  1
1992 Kish SJ, Bergeron C, Rajput A, Dozic S, Mastrogiacomo F, Chang LJ, Wilson JM, DiStefano LM, Nobrega JN. Brain cytochrome oxidase in Alzheimer's disease. Journal of Neurochemistry. 59: 776-9. PMID 1321237 DOI: 10.1111/J.1471-4159.1992.Tb09439.X  1
1992 Petrasek JS, Nobrega JN, Kish SJ, Burnham WM. Autoradiographic analysis of [35S]TBPS binding in entorhinal cortex-kindled rat brains. Brain Research. 570: 167-72. PMID 1319792 DOI: 10.1016/0006-8993(92)90578-W  1
1990 Saari MJ, Armstrong JN, Nobrega JN, Pappas BA, Coscina DV. Neonatal 6-hydroxydopamine alters the behavior of enriched-impoverished rats in a novel test environment. Behavioral Neuroscience. 104: 430-7. PMID 2112942 DOI: 10.1037//0735-7044.104.3.430  1
1989 Nobrega JN, Kish SJ, Burnham WM. Autoradiographic analysis of benzodiazepine binding in entorhinal-kindled rat brains. Brain Research. 498: 315-22. PMID 2790486 DOI: 10.1016/0006-8993(89)91110-4  1
1989 Coscina DV, Lacombe S, Chambers JW, Dixon L, Nobrega JN. Intake of greasy diets in hypothalamic obesity: a re-assessment. Appetite. 13: 15-24. PMID 2782864 DOI: 10.1016/0195-6663(89)90023-8  1
1989 Coscina DV, Nobrega JN. Effects of lateral hypothalamic lesions on the anorexia induced by ethanolamine-O-sulfate. Pharmacology, Biochemistry, and Behavior. 32: 275-81. PMID 2734338 DOI: 10.1016/0091-3057(89)90244-X  1
1983 Nobrega JN, Coscina DV. Chronic amitriptyline potentiates feeding induced by intrahypothalamic norepinephrine injections. Life Sciences. 33: 1249-53. PMID 6310296 DOI: 10.1016/0024-3205(83)90005-X  1
1982 Coscina DV, Nobrega JN. 6-Hydroxydopamine-induced blockade of hypothalamic obesity: critical role of brain dopamine-norepinephrine interaction. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 6: 369-72. PMID 6298885 DOI: 10.1016/S0278-5846(82)80109-7  1
1980 Nobrega JN, Wiener NI, Ossenkopp KP. Development of acute feeding disorders, hyperactivity, and stomach pathology after medial and lateral hypothalamic lesions in rats Physiological Psychology. 8: 77-87. DOI: 10.3758/Bf03326452  1
1979 Ossenkopp KP, Nobrega JN. Singificant relationship between perinatal geomagnetic field activity and anxiety levels in females Archiv FüR Meteorologie, Geophysik Und Bioklimatologie Serie B. 27: 75-90. DOI: 10.1007/BF02245912  1
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