Joel E. Schlosburg, PhD - Publications

Affiliations: 
Committee on the Neurobiology of Addictive Disorders Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Endocannabinoids, drug abuse, opiate self-administration

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mustafa MA, Poklis JL, Karin KN, Elmer JA, Porter JH, Parra V, Lu D, Schlosburg JE, Lichtman AH. Investigation of Cannabidiol in the Mouse Drug Discrimination Paradigm. Cannabis and Cannabinoid Research. PMID 36656312 DOI: 10.1089/can.2022.0198  0.524
2021 Dodu JC, Moncayo RK, Damaj MI, Schlosburg JE, Akbarali HI, O'Brien LD, Kendall DA, Lu D, Lichtman AH. The CB Receptor Positive Allosteric Modulator, ZCZ011, Attenuates Naloxone-Precipitated Diarrhea and Weight Loss in Oxycodone-Dependent Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 34625464 DOI: 10.1124/jpet.121.000723  0.571
2021 McGinn MA, Tunstall BJ, Schlosburg JE, Gregory-Flores A, George O, de Guglielmo G, Mason BJ, Hunt HJ, Koob GF, Vendruscolo LF. Glucocorticoid receptor modulators decrease alcohol self-administration in male rats. Neuropharmacology. 108510. PMID 33647278 DOI: 10.1016/j.neuropharm.2021.108510  0.606
2020 Muldoon PP, Akinola LS, Schlosburg JE, Lichtman AH, Sim-Selley LJ, Mahadevan A, Cravatt BF, Damaj MI. Inhibition of monoacylglycerol lipase reduces nicotine reward in the conditioned place preference test in male mice. Neuropharmacology. 108170. PMID 32479813 DOI: 10.1016/J.Neuropharm.2020.108170  0.537
2018 Serrano A, Pavon FJ, Buczynski MW, Schlosburg J, Natividad LA, Polis IY, Stouffer DG, Zorrilla EP, Roberto M, Cravatt BF, Martin-Fardon R, Rodriguez de Fonseca F, Parsons LH. Deficient endocannabinoid signaling in the central amygdala contributes to alcohol dependence-related anxiety-like behavior and excessive alcohol intake. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29748627 DOI: 10.1038/S41386-018-0055-3  0.705
2017 Bremer PT, Schlosburg JE, Banks ML, Steele FF, Zhou B, Poklis JL, Janda KD. Development of a Clinically-Viable Heroin Vaccine. Journal of the American Chemical Society. PMID 28574716 DOI: 10.1021/Jacs.7B03334  0.582
2016 Collins KC, Schlosburg JE, Bremer PT, Janda KD. Methamphetamine Vaccines: Improvement through Hapten Design. Journal of Medicinal Chemistry. PMID 27054372 DOI: 10.1021/Acs.Jmedchem.6B00084  0.532
2016 Jacob NT, Lockner JW, Schlosburg JE, Ellis BA, Eubanks LM, Janda KD. Investigations of Enantiopure Nicotine Haptens using an Adjuvanting Carrier in Anti-Nicotine Vaccine Development. Journal of Medicinal Chemistry. PMID 26918428 DOI: 10.1021/Acs.Jmedchem.5B01676  0.777
2016 Bremer PT, Kimishima A, Schlosburg JE, Zhou B, Collins KC, Janda KD. Combatting Synthetic Designer Opioids: A Conjugate Vaccine Ablates Lethal Doses of Fentanyl Class Drugs. Angewandte Chemie (International Ed. in English). PMID 26879590 DOI: 10.1002/Anie.201511654  0.78
2015 Xue S, Schlosburg JE, Janda KD. A New Strategy for Smoking Cessation: Characterization of a Bacterial Enzyme for the Degradation of Nicotine. Journal of the American Chemical Society. 137: 10136-9. PMID 26237398 DOI: 10.1021/Jacs.5B06605  0.441
2015 Viader A, Blankman JL, Zhong P, Liu X, Schlosburg JE, Joslyn CM, Liu QS, Tomarchio AJ, Lichtman AH, Selley DE, Sim-Selley LJ, Cravatt BF. Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action. Cell Reports. PMID 26212325 DOI: 10.1016/J.Celrep.2015.06.075  0.51
2015 Vendruscolo LF, Estey D, Goodell V, Macshane LG, Logrip ML, Schlosburg JE, McGinn MA, Zamora-Martinez ER, Belanoff JK, Hunt HJ, Sanna PP, George O, Koob GF, Edwards S, Mason BJ. Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals. The Journal of Clinical Investigation. PMID 26121746 DOI: 10.1172/Jci79828  0.694
2015 Repunte-Canonigo V, Shin W, Vendruscolo LF, Lefebvre C, van der Stap L, Kawamura T, Schlosburg JE, Alvarez M, Koob GF, Califano A, Sanna PP. Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks. Genome Biology. 16: 68. PMID 25886852 DOI: 10.1186/S13059-015-0593-5  0.489
2015 Whitfield TW, Schlosburg JE, Wee S, Gould A, George O, Grant Y, Zamora-Martinez ER, Edwards S, Crawford E, Vendruscolo LF, Koob GF. κ Opioid receptors in the nucleus accumbens shell mediate escalation of methamphetamine intake. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4296-305. PMID 25762676 DOI: 10.1523/Jneurosci.1978-13.2015  0.737
2015 Nass SR, Long JZ, Schlosburg JE, Cravatt BF, Lichtman AH, Kinsey SG. Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 10: 364-70. PMID 25715681 DOI: 10.1007/S11481-015-9593-1  0.744
2015 Lockner JW, Eubanks LM, Choi JL, Lively JM, Schlosburg JE, Collins KC, Globisch D, Rosenfeld-Gunn RJ, Wilson IA, Janda KD. Flagellin as carrier and adjuvant in cocaine vaccine development. Molecular Pharmaceutics. 12: 653-62. PMID 25531528 DOI: 10.1021/Mp500520R  0.773
2015 Schmeichel BE, Barbier E, Misra KK, Contet C, Schlosburg JE, Grigoriadis D, Williams JP, Karlsson C, Pitcairn C, Heilig M, Koob GF, Vendruscolo LF. Hypocretin receptor 2 antagonism dose-dependently reduces escalated heroin self-administration in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1123-9. PMID 25367502 DOI: 10.1038/Npp.2014.293  0.775
2015 Wade CL, Vendruscolo LF, Schlosburg JE, Hernandez DO, Koob GF. Compulsive-like responding for opioid analgesics in rats with extended access. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 421-8. PMID 25060491 DOI: 10.1038/Npp.2014.188  0.54
2015 Park PE, Schlosburg JE, Vendruscolo LF, Schulteis G, Edwards S, Koob GF. Chronic CRF1 receptor blockade reduces heroin intake escalation and dependence-induced hyperalgesia. Addiction Biology. 20: 275-84. PMID 24330252 DOI: 10.1111/Adb.12120  0.668
2014 Grieder TE, Herman MA, Contet C, Tan LA, Vargas-Perez H, Cohen A, Chwalek M, Maal-Bared G, Freiling J, Schlosburg JE, Clarke L, Crawford E, Koebel P, Repunte-Canonigo V, Sanna PP, et al. VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation. Nature Neuroscience. 17: 1751-8. PMID 25402857 DOI: 10.1038/Nn.3872  0.762
2014 Eubanks LM, Ellis BA, Cai X, Schlosburg JE, Janda KD. A human recombinant monoclonal antibody to cocaine: Preparation, characterization and behavioral studies. Bioorganic & Medicinal Chemistry Letters. 24: 4664-6. PMID 25205191 DOI: 10.1016/J.Bmcl.2014.08.035  0.481
2014 Schlosburg JE, Kinsey SG, Ignatowska-Jankowska B, Ramesh D, Abdullah RA, Tao Q, Booker L, Long JZ, Selley DE, Cravatt BF, Lichtman AH. Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 350: 196-204. PMID 24849924 DOI: 10.1124/Jpet.114.212753  0.779
2014 Collins KC, Schlosburg JE, Lockner JW, Bremer PT, Ellis BA, Janda KD. Lipid tucaresol as an adjuvant for methamphetamine vaccine development. Chemical Communications (Cambridge, England). 50: 4079-81. PMID 24615284 DOI: 10.1039/C4Cc00682H  0.767
2014 Logrip ML, Vendruscolo LF, Schlosburg JE, Koob GF, Zorrilla EP. Phosphodiesterase 10A regulates alcohol and saccharin self-administration in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1722-31. PMID 24549104 DOI: 10.1038/Npp.2014.20  0.662
2014 Bremer PT, Schlosburg JE, Lively JM, Janda KD. Injection route and TLR9 agonist addition significantly impact heroin vaccine efficacy. Molecular Pharmaceutics. 11: 1075-80. PMID 24517171 DOI: 10.1021/Mp400631W  0.575
2014 Koob GF, Buck CL, Cohen A, Edwards S, Park PE, Schlosburg JE, Schmeichel B, Vendruscolo LF, Wade CL, Whitfield TW, George O. Addiction as a stress surfeit disorder. Neuropharmacology. 76: 370-82. PMID 23747571 DOI: 10.1016/J.Neuropharm.2013.05.024  0.73
2014 Deschaux O, Vendruscolo LF, Schlosburg JE, Diaz-Aguilar L, Yuan CJ, Sobieraj JC, George O, Koob GF, Mandyam CD. Hippocampal neurogenesis protects against cocaine-primed relapse. Addiction Biology. 19: 562-74. PMID 23278919 DOI: 10.1111/Adb.12019  0.644
2013 Schlosburg JE, Whitfield TW, Park PE, Crawford EF, George O, Vendruscolo LF, Koob GF. Long-term antagonism of κ opioid receptors prevents escalation of and increased motivation for heroin intake. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 19384-92. PMID 24305833 DOI: 10.1523/Jneurosci.1979-13.2013  0.711
2013 Schlosburg JE, Vendruscolo LF, Bremer PT, Lockner JW, Wade CL, Nunes AA, Stowe GN, Edwards S, Janda KD, Koob GF. Dynamic vaccine blocks relapse to compulsive intake of heroin. Proceedings of the National Academy of Sciences of the United States of America. 110: 9036-41. PMID 23650354 DOI: 10.1073/Pnas.1219159110  0.805
2013 Park PE, Vendruscolo LF, Schlosburg JE, Edwards S, Schulteis G, Koob GF. Corticotropin-releasing factor (CRF) and α 2 adrenergic receptors mediate heroin withdrawal-potentiated startle in rats. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1867-75. PMID 23590881 DOI: 10.1017/S1461145713000308  0.658
2013 Barbier E, Vendruscolo LF, Schlosburg JE, Edwards S, Juergens N, Park PE, Misra KK, Cheng K, Rice KC, Schank J, Schulteis G, Koob GF, Heilig M. The NK1 receptor antagonist L822429 reduces heroin reinforcement. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 976-84. PMID 23303056 DOI: 10.1038/Npp.2012.261  0.71
2012 Schlosburg JE, Radanova L, Di Marzo V, Imming P, Lichtman AH. Evaluation of the endogenous cannabinoid system in mediating the behavioral effects of dipyrone (metamizol) in mice. Behavioural Pharmacology. 23: 722-6. PMID 22954646 DOI: 10.1097/Fbp.0B013E3283584794  0.607
2012 Wee S, Vendruscolo LF, Misra KK, Schlosburg JE, Koob GF. A combination of buprenorphine and naltrexone blocks compulsive cocaine intake in rodents without producing dependence. Science Translational Medicine. 4: 146ra110. PMID 22875830 DOI: 10.1126/Scitranslmed.3003948  0.533
2012 Vendruscolo LF, Barbier E, Schlosburg JE, Misra KK, Whitfield TW, Logrip ML, Rivier C, Repunte-Canonigo V, Zorrilla EP, Sanna PP, Heilig M, Koob GF. Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7563-71. PMID 22649234 DOI: 10.1523/Jneurosci.0069-12.2012  0.692
2012 Rogosch T, Sinning C, Podlewski A, Watzer B, Schlosburg J, Lichtman AH, Cascio MG, Bisogno T, Di Marzo V, Nüsing R, Imming P. Novel bioactive metabolites of dipyrone (metamizol). Bioorganic & Medicinal Chemistry. 20: 101-7. PMID 22172309 DOI: 10.1016/J.Bmc.2011.11.028  0.559
2012 Edwards S, Vendruscolo LF, Schlosburg JE, Misra KK, Wee S, Park PE, Schulteis G, Koob GF. Development of mechanical hypersensitivity in rats during heroin and ethanol dependence: alleviation by CRF₁ receptor antagonism. Neuropharmacology. 62: 1142-51. PMID 22119954 DOI: 10.1016/J.Neuropharm.2011.11.006  0.637
2011 Ramesh D, Schlosburg JE, Wiebelhaus JM, Lichtman AH. Marijuana dependence: not just smoke and mirrors. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 52: 295-308. PMID 23382144 DOI: 10.1093/Ilar.52.3.295  0.78
2011 Stowe GN, Schlosburg JE, Vendruscolo LF, Edwards S, Misra KK, Schulteis G, Zakhari JS, Koob GF, Janda KD. Developing a vaccine against multiple psychoactive targets: a case study of heroin. Cns & Neurological Disorders Drug Targets. 10: 865-75. PMID 22229311 DOI: 10.2174/187152711799219316  0.724
2011 Ramesh D, Ross GR, Schlosburg JE, Owens RA, Abdullah RA, Kinsey SG, Long JZ, Nomura DK, Sim-Selley LJ, Cravatt BF, Akbarali HI, Lichtman AH. Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice. The Journal of Pharmacology and Experimental Therapeutics. 339: 173-85. PMID 21719468 DOI: 10.1124/Jpet.111.181370  0.799
2011 Stowe GN, Vendruscolo LF, Edwards S, Schlosburg JE, Misra KK, Schulteis G, Mayorov AV, Zakhari JS, Koob GF, Janda KD. A vaccine strategy that induces protective immunity against heroin. Journal of Medicinal Chemistry. 54: 5195-204. PMID 21692508 DOI: 10.1021/Jm200461M  0.791
2011 Vendruscolo LF, Schlosburg JE, Misra KK, Chen SA, Greenwell TN, Koob GF. Escalation patterns of varying periods of heroin access. Pharmacology, Biochemistry, and Behavior. 98: 570-4. PMID 21406200 DOI: 10.1016/J.Pbb.2011.03.004  0.758
2011 Schlosburg JE, O'Neal ST, Conrad DH, Lichtman AH. CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action. Psychopharmacology. 216: 323-31. PMID 21340468 DOI: 10.1007/S00213-011-2224-5  0.597
2010 Schlosburg JE, Blankman JL, Long JZ, Nomura DK, Pan B, Kinsey SG, Nguyen PT, Ramesh D, Booker L, Burston JJ, Thomas EA, Selley DE, Sim-Selley LJ, Liu QS, Lichtman AH, et al. Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system. Nature Neuroscience. 13: 1113-9. PMID 20729846 DOI: 10.1038/Nn.2616  0.8
2010 Falenski KW, Thorpe AJ, Schlosburg JE, Cravatt BF, Abdullah RA, Smith TH, Selley DE, Lichtman AH, Sim-Selley LJ. FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1775-87. PMID 20357755 DOI: 10.1038/Npp.2010.44  0.694
2009 Schlosburg JE, Carlson BL, Ramesh D, Abdullah RA, Long JZ, Cravatt BF, Lichtman AH. Inhibitors of endocannabinoid-metabolizing enzymes reduce precipitated withdrawal responses in THC-dependent mice. The Aaps Journal. 11: 342-52. PMID 19430909 DOI: 10.1208/S12248-009-9110-7  0.747
2009 Schlosburg JE, Kinsey SG, Lichtman AH. Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation. The Aaps Journal. 11: 39-44. PMID 19184452 DOI: 10.1208/S12248-008-9075-Y  0.751
2009 Schlosburg JE, Boger DL, Cravatt BF, Lichtman AH. Endocannabinoid modulation of scratching response in an acute allergenic model: a new prospective neural therapeutic target for pruritus. The Journal of Pharmacology and Experimental Therapeutics. 329: 314-23. PMID 19168707 DOI: 10.1124/Jpet.108.150136  0.564
2009 Long JZ, Li W, Booker L, Burston JJ, Kinsey SG, Schlosburg JE, Pavón FJ, Serrano AM, Selley DE, Parsons LH, Lichtman AH, Cravatt BF. Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. Nature Chemical Biology. 5: 37-44. PMID 19029917 DOI: 10.1038/Nchembio.129  0.771
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