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Catherine Cook Kaczorowski, PhD Neuroscience - Publications

Affiliations: 
2016- The Jackson Laboratory, Bar Harbor, ME, United States 
Area:
Aging & Alzheimer's Disease
Website:
https://www.jax.org/research-and-faculty/faculty/catherine-kaczorowski
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56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hurst CD, Dunn AR, Dammer EB, Duong DM, Seyfried NT, Kaczorowski CC, Johnson ECB. Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome. Biorxiv : the Preprint Server For Biology. PMID 37398142 DOI: 10.1101/2023.06.12.544646  0.741
2023 Gurdon B, Yates SC, Csucs G, Groeneboom NE, Hadad N, Telpoukhovskaia M, Ouellette A, Ouellette T, O'Connell K, Singh S, Murdy T, Merchant E, Bjerke I, Kleven H, Schlegel U, ... ... Kaczorowski CC, et al. Detecting the effect of genetic diversity on brain composition in an Alzheimer's disease mouse model. Biorxiv : the Preprint Server For Biology. PMID 36909528 DOI: 10.1101/2023.02.27.530226  0.726
2023 Welikovitch LA, Dujardin S, Dunn AR, Fernandes AR, Khasnavis A, Chibnik LB, Kaczorowski CC, Hyman BT. Rate of tau propagation is a heritable disease trait in genetically diverse mouse strains. Iscience. 26: 105983. PMID 36756365 DOI: 10.1016/j.isci.2023.105983  0.724
2023 Murdy TJ, Dunn AR, Singh S, Telpoukhovskaia MA, Zhang S, White JK, Kahn I, Febo M, Kaczorowski CC. Leveraging genetic diversity in mice to inform individual differences in brain microstructure and memory. Frontiers in Behavioral Neuroscience. 16: 1033975. PMID 36703722 DOI: 10.3389/fnbeh.2022.1033975  0.823
2022 Ouellette AR, Hadad N, Deighan A, Robinson L, O'Connell K, Freund A, Churchill GA, Kaczorowski CC. Life-long dietary restrictions have negligible or damaging effects on late-life cognitive performance: A key role for genetics in outcomes. Neurobiology of Aging. 118: 108-116. PMID 35914473 DOI: 10.1016/j.neurobiolaging.2022.07.004  0.807
2022 Eissman JM, Dumitrescu L, Mahoney ER, Smith AN, Mukherjee S, Lee ML, Scollard P, Choi SE, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski CC, et al. Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease. Brain : a Journal of Neurology. PMID 35552371 DOI: 10.1093/brain/awac177  0.758
2022 Neuner SM, Telpoukhovskaia M, Menon V, O'Connell KMS, Hohman TJ, Kaczorowski CC. Translational approaches to understanding resilience to Alzheimer's disease. Trends in Neurosciences. PMID 35307206 DOI: 10.1016/j.tins.2022.02.005  0.829
2021 Gurdon B, Kaczorowski C. Pursuit of precision medicine: Systems biology approaches in Alzheimer's disease mouse models. Neurobiology of Disease. 161: 105558. PMID 34767943 DOI: 10.1016/j.nbd.2021.105558  0.805
2021 Roy S, Sleiman MB, Jha P, Ingels JF, Chapman CJ, McCarty MS, Ziebarth JD, Hook M, Sun A, Zhao W, Huang J, Neuner SM, Wilmott LA, Shapaker TM, Centeno AG, ... ... Kaczorowski CC, et al. Gene-by-environment modulation of lifespan and weight gain in the murine BXD family. Nature Metabolism. 3: 1217-1227. PMID 34552269 DOI: 10.1038/s42255-021-00449-w  0.764
2021 Nackenoff AG, Hohman TJ, Neuner SM, Akers CS, Weitzel NC, Shostak A, Ferguson SM, Mobley B, Bennett DA, Schneider JA, Jefferson AL, Kaczorowski CC, Schrag MS. PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer's disease. Plos Genetics. 17: e1009406. PMID 33830999 DOI: 10.1371/journal.pgen.1009406  0.738
2020 McQuail JA, Dunn AR, Stern Y, Barnes CA, Kempermann G, Rapp PR, Kaczorowski CC, Foster TC. Cognitive Reserve in Model Systems for Mechanistic Discovery: The Importance of Longitudinal Studies. Frontiers in Aging Neuroscience. 12: 607685. PMID 33551788 DOI: 10.3389/fnagi.2020.607685  0.69
2020 Dunn AR, Hadad N, Neuner SM, Zhang JG, Philip VM, Dumitrescu L, Hohman TJ, Herskowitz JH, O'Connell KMS, Kaczorowski CC. Identifying Mechanisms of Normal Cognitive Aging Using a Novel Mouse Genetic Reference Panel. Frontiers in Cell and Developmental Biology. 8: 562662. PMID 33042997 DOI: 10.3389/Fcell.2020.562662  0.797
2020 Ouellette AR, Neuner SM, Dumitrescu L, Anderson LC, Gatti DM, Mahoney ER, Bubier JA, Churchill G, Peters L, Huentelman MJ, Herskowitz JH, Yang HS, Smith AN, Reitz C, Kunkle BW, ... ... Kaczorowski CC, et al. Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia. Cell Reports. 32: 108091. PMID 32877673 DOI: 10.1016/J.Celrep.2020.108091  0.823
2020 Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski C, Hernandez Saucedo H, Widaman KF, Buckley R, Properzi M, et al. Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Brain : a Journal of Neurology. 143: 2561-2575. PMID 32844198 DOI: 10.1093/Brain/Awaa209  0.782
2020 Heuer SE, Neuner SM, Hadad N, O'Connell KMS, Williams RW, Philip VM, Gaiteri C, Kaczorowski CC. Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice. Learning & Memory (Cold Spring Harbor, N.Y.). 27: 355-371. PMID 32817302 DOI: 10.1101/Lm.051839.120  0.828
2020 Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, et al. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Reports. 32: 107908. PMID 32668255 DOI: 10.1016/J.Celrep.2020.107908  0.748
2020 Hohman TJ, Kaczorowski CC. Modifiable Lifestyle Factors in Alzheimer Disease: An Opportunity to Transform the Therapeutic Landscape Through Transdisciplinary Collaboration. Jama Neurology. PMID 32597936 DOI: 10.1001/Jamaneurol.2020.1114  0.362
2020 An JY, Kerns KA, Ouellette A, Robinson L, Morris HD, Kaczorowski C, Park SI, Mekvanich T, Kang A, McLean JS, Cox TC, Kaeberlein M. Rapamycin rejuvenates oral health in aging mice. Elife. 9. PMID 32342860 DOI: 10.7554/Elife.54318  0.781
2020 An JY, Kerns KA, Ouellette A, Robinson L, Morris HD, Kaczorowski C, Park S, Mekvanich T, Kang A, McLean JS, Cox TC, Kaeberlein M. Author response: Rapamycin rejuvenates oral health in aging mice Elife. DOI: 10.7554/Elife.54318.Sa2  0.766
2019 Dunn AR, Kaczorowski CC. Regulation of intrinsic excitability: Roles for learning and memory, aging and Alzheimer's disease, and genetic diversity. Neurobiology of Learning and Memory. 107069. PMID 31442579 DOI: 10.1016/J.Nlm.2019.107069  0.761
2019 O'Connell KMS, Ouellette AR, Neuner SM, Dunn AR, Kaczorowski CC. Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse model of genetic diversity in Alzheimer's disease. Genes, Brain, and Behavior. e12603. PMID 31381246 DOI: 10.1111/Gbb.12603  0.826
2019 Dunn AR, O'Connell KMS, Kaczorowski CC. Gene-by-environment interactions in Alzheimer's disease and Parkinson's disease. Neuroscience and Biobehavioral Reviews. PMID 31207254 DOI: 10.1016/J.Neubiorev.2019.06.018  0.733
2019 Mulligan MK, Abreo T, Neuner SM, Parks C, Watkins CE, Houseal MT, Shapaker TM, Hook M, Tan H, Wang X, Ingels J, Peng J, Lu L, Kaczorowski CC, Bryant CD, et al. Identification of a Functional Non-coding Variant in the GABA Receptor α2 Subunit of the C57BL/6J Mouse Reference Genome: Major Implications for Neuroscience Research. Frontiers in Genetics. 10: 188. PMID 30984232 DOI: 10.3389/Fgene.2019.00188  0.725
2019 Neuner SM, Heuer SE, Zhang JG, Philip VM, Kaczorowski CC. Identification of Pre-symptomatic Gene Signatures That Predict Resilience to Cognitive Decline in the Genetically Diverse AD-BXD Model. Frontiers in Genetics. 10: 35. PMID 30787942 DOI: 10.3389/Fgene.2019.00035  0.836
2019 Kaczorowski C, Heuer S, Gaiteri C, Kaczorowski C. MULTI-OMICS ANALYSIS IDENTIFIES GENE NETWORKS ASSOCIATED WITH COGNITIVE AGING AND ALZHEIMER’S DISEASE Innovation in Aging. 3: S587-S588. DOI: 10.1093/Geroni/Igz038.2179  0.731
2019 Heuer SE, Neuner SM, Gaiteri C, Kaczorowski CC. O4-10-05: MULTI-OMIC ANALYSIS IDENTIFIES TRANSCRIPTIONAL NETWORKS AND DRIVERS ASSOCIATED WITH COGNITIVE AGING AND ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P1260-P1261. DOI: 10.1016/J.Jalz.2019.06.4798  0.803
2019 Dunn AR, Ouellette AR, Neuner SM, Zhang J, Philip V, O'Connell K, Kaczorowski CC. P4-088: GENE-BY-ENVIRONMENT REGULATION OF ALZHEIMER'S DISEASE PATHOGENESIS Alzheimer's & Dementia. 15: P1308-P1308. DOI: 10.1016/J.Jalz.2019.06.3748  0.8
2019 Kaczorowski CC, Dunn AR, Neuner SM, Kumar V, O'Connell KM. P2-138: IDENTIFICATION OF SIPA1L1 AS A NOVEL CANDIDATE GENE MEDIATING PRECLINICAL WEIGHT LOSS IN A MOUSE MODEL OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P625-P625. DOI: 10.1016/J.Jalz.2019.06.2545  0.81
2019 Grudny M, Neuner SM, Dunn AR, Pompilus M, Kaczorowski CC, Febo M. P2-130: BACKGROUND GENETICS IMPACTS MICROSTRUCTURE MEASURES IN MOTOR CORTEX AND HIPPOCAMPUS OF WILDTYPE AND 5XFAD MICE Alzheimer's & Dementia. 15: P622-P622. DOI: 10.1016/J.Jalz.2019.06.2537  0.776
2018 Dunn AR, Neuner SM, Ding S, Hope KA, O'Connell KMS, Kaczorowski CC. Cell-Type-Specific Changes in Intrinsic Excitability in the Subiculum following Learning and Exposure to Novel Environmental Contexts. Eneuro. 5. PMID 30627661 DOI: 10.1523/ENEURO.0484-18.2018  0.764
2018 Neuner SM, Heuer SE, Huentelman MJ, O'Connell KMS, Kaczorowski CC. Harnessing Genetic Complexity to Enhance Translatability of Alzheimer's Disease Mouse Models: A Path toward Precision Medicine. Neuron. PMID 30595332 DOI: 10.1016/J.Neuron.2018.11.040  0.822
2018 Neuner SM, Ding S, Kaczorowski CC. Knockdown of heterochromatin protein 1 binding protein 3 recapitulates phenotypic, cellular, and molecular features of aging. Aging Cell. e12886. PMID 30549219 DOI: 10.1111/Acel.12886  0.813
2017 Neuner SM, Wilmott LA, Hope KA, Hoffmann B, Chong JA, Abramowitz J, Birnbaumer L, O'Connell K, Tryba AK, Greene AS, Chan CS, Kaczorowski CC. Corrigendum to "TRPC3 channels critically regulate hippocampal excitability and contextual fear memory" Behav. Brain Res. 281(March) 2015, 69-77. Behavioural Brain Research. PMID 28576459 DOI: 10.1016/J.Bbr.2017.05.038  0.757
2017 Wilmott LA, Neuner SM, Burger C, Kaczorowski C. Advances at the intersection of normal brain aging and Alzheimer's disease. Behavioural Brain Research. 322: 187-190. PMID 28231898 DOI: 10.1016/J.Bbr.2017.01.052  0.815
2017 Neuner SM, Wilmott LA, O'Connell KM, Kaczorowski CC. [P2-103]: MAPPING RESILIENCE TO MOTOR SYMPTOMS AND FRAILTY IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 13: P646-P646. DOI: 10.1016/J.Jalz.2017.06.752  0.784
2017 Neuner SM, Kaczorowski CC. [P3-104]: DISCOVERING GENETIC MODIFIERS OF ALZHEIMER's DISEASE USING NOVEL MOUSE MODELS Alzheimer's & Dementia. 13: P975-P975. DOI: 10.1016/J.Jalz.2017.06.1315  0.744
2016 Garfinkel BP, Arad S, Neuner S, Netser S, Wagner S, Kaczorowski CC, Rosen CJ, Gal M, Soreq H, Orly J. HP1BP3 expression determines maternal behavior and offspring survival. Genes, Brain, and Behavior. PMID 27470444 DOI: 10.1111/Gbb.12312  0.664
2016 Neuner SM, Garfinkel BP, Wilmott LA, Ignatowska-Jankowska BM, Citri A, Orly J, Lu L, Overall RW, Mulligan MK, Kempermann G, Williams RW, O'Connell KM, Kaczorowski CC. Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging. Neurobiology of Aging. 46: 58-67. PMID 27460150 DOI: 10.1016/J.Neurobiolaging.2016.06.008  0.814
2016 Neuner SM, Wilmott LA, Hoffmann BR, Mozhui K, Kaczorowski CC. Hippocampal proteomics defines pathways associated with memory decline and resilience in 'normal' aging and Alzheimer's disease mouse models. Behavioural Brain Research. PMID 27265785 DOI: 10.1016/J.Bbr.2016.06.002  0.825
2016 Graves AR, Moore SJ, Spruston N, Tryba AK, Kaczorowski CC. Brain derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons. Journal of Neurophysiology. jn.00186.2016. PMID 27146982 DOI: 10.1152/Jn.00186.2016  0.777
2016 Prisco AR, Hoffmann BR, Kaczorowski CC, McDermott-Roe C, Stodola TJ, Exner EC, Greene AS. TNFα Regulates Endothelial Progenitor Cell Migration via CADM1 and NF-kB. Stem Cells (Dayton, Ohio). PMID 26867147 DOI: 10.1002/Stem.2339  0.76
2015 Neuner SM, Wilmott LA, Hope KA, Hoffmann B, Chong JA, Abramowitz J, Birnbaumer L, O'Connell KM, Tryba AK, Greene AS, Savio Chan C, Kaczorowski CC. TRPC3 channels critically regulate hippocampal excitability and contextual fear memory. Behavioural Brain Research. 281: 69-77. PMID 25513972 DOI: 10.1016/J.Bbr.2014.12.018  0.756
2015 Li L, Chen E, Yang C, Zhu J, Jayaraman P, De Pons J, Kaczorowski CC, Jacob HJ, Greene AS, Hodges MR, Cowley AW, Liang M, Xu H, Liu P, Lu Y. Improved rat genome gene prediction by integration of ESTs with RNA-Seq information. Bioinformatics (Oxford, England). 31: 25-32. PMID 25217576 DOI: 10.1093/Bioinformatics/Btu608  0.577
2015 Neuner SM, Wilmott L, DeBoth M, Shapaker T, Ingels J, Lu L, Williams R, Kempermann G, Huentelman M, Kaczorowski CC. Multi-scale study of normal aging predicts novel late-onset Alzheimer's disease risk variants Bmc Bioinformatics. 16: P11. DOI: 10.1186/1471-2105-16-S15-P11  0.795
2014 Baver SB, Hope K, Guyot S, Bjørbaek C, Kaczorowski C, O'Connell KM. Leptin modulates the intrinsic excitability of AgRP/NPY neurons in the arcuate nucleus of the hypothalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5486-96. PMID 24741039 DOI: 10.1523/Jneurosci.4861-12.2014  0.732
2013 Kaczorowski CC, Stodola TJ, Hoffmann BR, Prisco AR, Liu PY, Didier DN, Karcher JR, Liang M, Jacob HJ, Greene AS. Targeting the endothelial progenitor cell surface proteome to identify novel mechanisms that mediate angiogenic efficacy in a rodent model of vascular disease. Physiological Genomics. 45: 999-1011. PMID 24022221 DOI: 10.1152/Physiolgenomics.00097.2013  0.769
2012 Kaczorowski CC, Davis SJ, Moyer JR. Aging redistributes medial prefrontal neuronal excitability and impedes extinction of trace fear conditioning. Neurobiology of Aging. 33: 1744-57. PMID 21531046 DOI: 10.1016/J.Neurobiolaging.2011.03.020  0.731
2011 Tryba AK, Kaczorowski CC, Ben-Mabrouk F, Elsen FP, Lew SM, Marcuccilli CJ. Rhythmic intrinsic bursting neurons in human neocortex obtained from pediatric patients with epilepsy. The European Journal of Neuroscience. 34: 31-44. PMID 21722205 DOI: 10.1111/J.1460-9568.2011.07746.X  0.694
2011 Kaczorowski CC, Sametsky E, Shah S, Vassar R, Disterhoft JF. Mechanisms underlying basal and learning-related intrinsic excitability in a mouse model of Alzheimer's disease. Neurobiology of Aging. 32: 1452-65. PMID 19833411 DOI: 10.1016/J.Neurobiolaging.2009.09.003  0.777
2009 Kaczorowski CC, Disterhoft JF. Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice. Learning & Memory (Cold Spring Harbor, N.Y.). 16: 362-6. PMID 19470651 DOI: 10.1101/Lm.1365609  0.693
2007 Kaczorowski CC, Disterhoft J, Spruston N. Stability and plasticity of intrinsic membrane properties in hippocampal CA1 pyramidal neurons: effects of internal anions. The Journal of Physiology. 578: 799-818. PMID 17138601 DOI: 10.1113/Jphysiol.2006.124586  0.741
2006 Howel G Acosta G, Neuner SM, Ouellette A, O'Connell K, Kaczorowski CC. P2-110: CNS-MEDIATED SENSORIMOTOR DECLINE IN A NOVEL TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P711-P711. DOI: 10.1016/J.Jalz.2018.06.796  0.817
2006 Preuss C, Wang X, Ananda G, Neuner SM, Philip V, Nho K, Logsdon B, Lamb BT, Kaczorowski CC, Sasner M, Howell GR, Carter GW. O4-01-06: WHOLE-EXOME ANALYSIS OF LATE-ONSET ALZHEIMER'S DISEASE REVEALS NOVEL CANDIDATE GENES INVOLVED IN COGNITIVE FUNCTION Alzheimer's & Dementia. 14: P1402-P1402. DOI: 10.1016/J.Jalz.2018.06.2914  0.735
2006 Neuner SM, Philip V, Huentelman MJ, Kaczorowski CC. P4-048: IDENTIFYING PRESYMPTOMATIC GENE SIGNATURES PREDICTIVE OF RESILIENCE TO ALZHEIMER'S Alzheimer's & Dementia. 14: P1451-P1452. DOI: 10.1016/J.Jalz.2018.06.2450  0.704
2006 Dunn A, Ouellette A, Neuner SM, O'Connell KM, Kaczorowski CC. P1-147: GENE X DIET INTERACTIONS MODIFY SYMPTOMS OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P332-P333. DOI: 10.1016/J.Jalz.2018.06.150  0.785
2006 O'Connell KM, Dunn A, Ouellette A, Neuner SM, Kaczorowski CC. P3-138: HYPOTHALAMIC ENERGY BALANCE DYSFUNCTION IN THE ETIOLOGY OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1121-P1121. DOI: 10.1016/J.Jalz.2018.06.1495  0.791
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