Debabrata Chakravarti - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Biochemistry, Molecular Biology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Park J, Kim JY, Park JW, Kang JY, Oh H, Hahm JY, Chae YC, Chakravarti D, Seo SB. INHAT subunit SET/TAF-Iβ regulates PRC1-independent H2AK119 mono-ubiquitination via E3 ligase MIB1 in colon cancer. Nar Cancer. 5: zcad050. PMID 37746636 DOI: 10.1093/narcan/zcad050  0.451
2022 Holmes AG, Parker JB, Sagar V, Truica MI, Soni PN, Han H, Schiltz GE, Abdulkadir SA, Chakravarti D. A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression. Science Advances. 8: eabh3635. PMID 35476451 DOI: 10.1126/sciadv.abh3635  0.39
2020 Liu S, Yin P, Dotts AJ, Kujawa SA, Coon V JS, Wei JJ, Chakravarti D, Bulun SE. Activation of protein kinase B by WNT4 as a regulator of uterine leiomyoma stem cell function. Fertility and Sterility. PMID 32892998 DOI: 10.1016/J.Fertnstert.2020.06.045  0.348
2020 Li Y, Qiang W, Griffin BB, Gao T, Chakravarti D, Bulun S, Kim JJ, Wei JJ. HMGA2-mediated tumorigenesis through angiogenesis in leiomyoma. Fertility and Sterility. PMID 32868105 DOI: 10.1016/J.Fertnstert.2020.05.036  0.34
2020 Vatapalli R, Sagar V, Rodriguez Y, Zhao JC, Unno K, Pamarthy S, Lysy B, Anker J, Han H, Yoo YA, Truica M, Chalmers ZR, Giles F, Yu J, Chakravarti D, et al. Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer. Nature Communications. 11: 4153. PMID 32814769 DOI: 10.1038/S41467-020-18013-7  0.429
2020 Moyo MB, Parker JB, Chakravarti D. Altered chromatin landscape and enhancer engagement underlie transcriptional dysregulation in MED12 mutant uterine leiomyomas. Nature Communications. 11: 1019. PMID 32094355 DOI: 10.1038/S41467-020-14701-6  0.506
2018 Xie J, Xu X, Yin P, Li Y, Guo H, Kujawa S, Chakravarti D, Bulun S, Kim JJ, Wei JJ. Application of ex-vivo spheroid model system for the analysis of senescence and senolytic phenotypes in uterine leiomyoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30206313 DOI: 10.1038/S41374-018-0117-5  0.32
2016 Vidimar V, Gius D, Chakravarti D, Bulun SE, Wei JJ, Kim JJ. Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas. Science Advances. 2: e1601132. PMID 27847869 DOI: 10.1126/Sciadv.1601132  0.325
2016 Kim JY, Yu J, Abdulkadir SA, Chakravarti D. KAT8 regulates androgen signaling in prostate cancer cells. Molecular Endocrinology (Baltimore, Md.). me20161024. PMID 27268279 DOI: 10.1210/Me.2016-1024  0.464
2015 Vinckevicius A, Parker JB, Chakravarti D. Genomic determinants of THAP11/ZNF143/HCFC1 complex recruitment to chromatin. Molecular and Cellular Biology. PMID 26416877 DOI: 10.1128/Mcb.00477-15  0.527
2015 Zhang A, Zhao JC, Kim J, Fong KW, Yang YA, Chakravarti D, Mo YY, Yu J. LncRNA HOTAIR Enhances the Androgen-Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer. Cell Reports. PMID 26411689 DOI: 10.1016/J.Celrep.2015.08.069  0.341
2015 Bulun SE, Moravek MB, Yin P, Ono M, Coon V JS, Dyson MT, Navarro A, Marsh EE, Zhao H, Maruyama T, Chakravarti D, Kim JJ, Wei JJ. Uterine Leiomyoma Stem Cells: Linking Progesterone to Growth. Seminars in Reproductive Medicine. 33: 357-65. PMID 26251118 DOI: 10.1055/S-0035-1558451  0.301
2015 Kim JY, Banerjee T, Vinckevicius A, Luo Q, Parker JB, Baker MR, Radhakrishnan I, Wei JJ, Barish GD, Chakravarti D. A Role for WDR5 in integrating threonine 11 phosphorylation to lysine 4 methylation on histone h3 during androgen signaling and in prostate cancer [Molecular Cell, 54, (2014), 613-625] Molecular Cell. 58: 557. DOI: 10.1016/J.Molcel.2015.04.030  0.46
2014 Parker JB, Yin H, Vinckevicius A, Chakravarti D. Host cell factor-1 recruitment to E2F-bound and cell-cycle-control genes is mediated by THAP11 and ZNF143. Cell Reports. 9: 967-82. PMID 25437553 DOI: 10.1016/J.Celrep.2014.09.051  0.436
2014 Kim JY, Banerjee T, Vinckevicius A, Luo Q, Parker JB, Baker MR, Radhakrishnan I, Wei JJ, Barish GD, Chakravarti D. A role for WDR5 in integrating threonine 11 phosphorylation to lysine 4 methylation on histone H3 during androgen signaling and in prostate cancer. Molecular Cell. 54: 613-25. PMID 24793694 DOI: 10.1016/J.Molcel.2014.03.043  0.49
2013 Ono M, Yin P, Navarro A, Moravek MB, Coon JS, Druschitz SA, Serna VA, Qiang W, Brooks DC, Malpani SS, Ma J, Ercan CM, Mittal N, Monsivais D, Dyson MT, ... ... Chakravarti D, et al. Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 110: 17053-8. PMID 24082114 DOI: 10.1073/Pnas.1313650110  0.317
2013 Sefton EC, Qiang W, Serna V, Kurita T, Wei JJ, Chakravarti D, Kim JJ. MK-2206, an AKT inhibitor, promotes caspase-independent cell death and inhibits leiomyoma growth. Endocrinology. 154: 4046-57. PMID 24002033 DOI: 10.1210/En.2013-1389  0.344
2013 Ma JJ, Monsivais D, Dyson MT, Coon JS, Malpani S, Ono M, Zhao H, Xin H, Pavone ME, Kim JJ, Chakravarti D, Bulun SE. Ligand-activated peroxisome proliferator-activated receptor β/δ modulates human endometrial cancer cell survival. Hormones & Cancer. 4: 358-70. PMID 23943160 DOI: 10.1007/S12672-013-0157-7  0.332
2013 Yin H, Lo JH, Kim JY, Marsh EE, Kim JJ, Ghosh AK, Bulun S, Chakravarti D. Expression profiling of nuclear receptors identifies key roles of NR4A subfamily in uterine fibroids. Molecular Endocrinology (Baltimore, Md.). 27: 726-40. PMID 23550059 DOI: 10.1210/Me.2012-1305  0.323
2012 Vinckevicius A, Chakravarti D. Chromatin immunoprecipitation: advancing analysis of nuclear hormone signaling. Journal of Molecular Endocrinology. 49: R113-23. PMID 22872135 DOI: 10.1530/Jme-12-0016  0.489
2012 Kim JY, Kim KB, Eom GH, Choe N, Kee HJ, Son HJ, Oh ST, Kim DW, Pak JH, Baek HJ, Kook H, Hahn Y, Kook H, Chakravarti D, Seo SB. KDM3B is the H3K9 demethylase involved in transcriptional activation of lmo2 in leukemia. Molecular and Cellular Biology. 32: 2917-33. PMID 22615488 DOI: 10.1128/Mcb.00133-12  0.576
2012 Parker JB, Palchaudhuri S, Yin H, Wei J, Chakravarti D. A transcriptional regulatory role of the THAP11-HCF-1 complex in colon cancer cell function. Molecular and Cellular Biology. 32: 1654-70. PMID 22371484 DOI: 10.1128/Mcb.06033-11  0.488
2012 Kim JY, Lee KS, Seol JE, Yu K, Chakravarti D, Seo SB. Inhibition of p53 acetylation by INHAT subunit SET/TAF-Iβ represses p53 activity. Nucleic Acids Research. 40: 75-87. PMID 21911363 DOI: 10.1093/Nar/Gkr614  0.423
2011 Banerjee T, Chakravarti D. A peek into the complex realm of histone phosphorylation. Molecular and Cellular Biology. 31: 4858-73. PMID 22006017 DOI: 10.1128/Mcb.05631-11  0.629
2010 Yin P, Lin Z, Reierstad S, Wu J, Ishikawa H, Marsh EE, Innes J, Cheng Y, Pearson K, Coon JS, Kim JJ, Chakravarti D, Bulun SE. Transcription factor KLF11 integrates progesterone receptor signaling and proliferation in uterine leiomyoma cells. Cancer Research. 70: 1722-30. PMID 20124487 DOI: 10.1158/0008-5472.Can-09-2612  0.318
2009 Buranapramest M, Chakravarti D. Chromatin remodeling and nuclear receptor signaling. Progress in Molecular Biology and Translational Science. 87: 193-234. PMID 20374705 DOI: 10.1016/S1877-1173(09)87006-3  0.606
2009 Chakravarti D. Regulatory mechanisms in transcriptional signaling by nuclear hormone receptors, and their regulators: implications in physiology and disease. Introduction. Progress in Molecular Biology and Translational Science. 87: xv-xxii. PMID 20374699 DOI: 10.1016/S1877-1173(09)87016-6  0.42
2009 Loomis RJ, Naoe Y, Parker JB, Savic V, Bozovsky MR, Macfarlan T, Manley JL, Chakravarti D. Chromatin binding of SRp20 and ASF/SF2 and dissociation from mitotic chromosomes is modulated by histone H3 serine 10 phosphorylation. Molecular Cell. 33: 450-61. PMID 19250906 DOI: 10.1016/J.Molcel.2009.02.003  0.771
2009 Hoekstra AV, Sefton EC, Berry E, Lu Z, Hardt J, Marsh E, Yin P, Clardy J, Chakravarti D, Bulun S, Kim JJ. Progestins activate the AKT pathway in leiomyoma cells and promote survival. The Journal of Clinical Endocrinology and Metabolism. 94: 1768-74. PMID 19240153 DOI: 10.1210/Jc.2008-2093  0.347
2009 Hoekstra AV, Sefton EC, Berry E, Lu Z, Hardt J, Marsh E, Yin P, Clardy J, Chakravarti D, Bulun S, Kim JJ. Progestins Activate the AKT Pathway in Leiomyoma Cells and Promote Survival Molecular Endocrinology. 23: 585-585. DOI: 10.1210/Mend.23.4.9996  0.332
2007 Ewing AK, Attner M, Chakravarti D. Novel regulatory role for human Acf1 in transcriptional repression of vitamin D3 receptor-regulated genes. Molecular Endocrinology (Baltimore, Md.). 21: 1791-806. PMID 17519354 DOI: 10.1210/Me.2007-0095  0.534
2007 Ishikawa H, Fencki V, Yin P, Marsh E, Chakravarti D, Bulun S. CCAAT enhancer binding protein beta (C/EBPβ) regulates aromatase P450 expression VIA new cis-acting element in uterine leiomyoma cells Fertility and Sterility. 88: S71-S72. DOI: 10.1016/J.Fertnstert.2007.07.241  0.334
2006 Macfarlan T, Parker JB, Nagata K, Chakravarti D. Thanatos-associated protein 7 associates with template activating factor-Ibeta and inhibits histone acetylation to repress transcription. Molecular Endocrinology (Baltimore, Md.). 20: 335-47. PMID 16195249 DOI: 10.1210/Me.2005-0248  0.81
2005 Macfarlan T, Kutney S, Altman B, Montross R, Yu J, Chakravarti D. Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressor. The Journal of Biological Chemistry. 280: 7346-58. PMID 15561719 DOI: 10.1074/Jbc.M411675200  0.728
2004 Hong R, Macfarlan T, Kutney SN, Seo SB, Mukai Y, Yelin F, Pasternack GR, Chakravarti D. The identification of phosphorylation sites of pp32 and biochemical purification of a cellular pp32-kinase. Biochemistry. 43: 10157-65. PMID 15287743 DOI: 10.1021/Bi0493968  0.674
2004 Kutney SN, Hong R, Macfarlan T, Chakravarti D. A signaling role of histone-binding proteins and INHAT subunits pp32 and Set/TAF-Ibeta in integrating chromatin hypoacetylation and transcriptional repression. The Journal of Biological Chemistry. 279: 30850-5. PMID 15136563 DOI: 10.1074/Jbc.M404969200  0.73
2004 Curtis AM, Seo SB, Westgate EJ, Rudic RD, Smyth EM, Chakravarti D, FitzGerald GA, McNamara P. Histone acetyltransferase-dependent chromatin remodeling and the vascular clock. The Journal of Biological Chemistry. 279: 7091-7. PMID 14645221 DOI: 10.1074/Jbc.M311973200  0.53
2003 Hong R, Chakravarti D. The human proliferating Cell nuclear antigen regulates transcriptional coactivator p300 activity and promotes transcriptional repression. The Journal of Biological Chemistry. 278: 44505-13. PMID 12937166 DOI: 10.1074/Jbc.M303138200  0.541
2003 van Leeuwen H, Okuwaki M, Hong R, Chakravarti D, Nagata K, O'Hare P. Herpes simplex virus type 1 tegument protein VP22 interacts with TAF-I proteins and inhibits nucleosome assembly but not regulation of histone acetylation by INHAT. The Journal of General Virology. 84: 2501-10. PMID 12917472 DOI: 10.1099/Vir.0.19326-0  0.567
2002 Li F, Macfarlan T, Pittman RN, Chakravarti D. Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities. The Journal of Biological Chemistry. 277: 45004-12. PMID 12297501 DOI: 10.1074/Jbc.M205259200  0.785
2002 Hong W, Kim AY, Ky S, Rakowski C, Seo SB, Chakravarti D, Atchison M, Blobel GA. Inhibition of CBP-mediated protein acetylation by the Ets family oncoprotein PU.1 Molecular and Cellular Biology. 22: 3729-3743. PMID 11997509 DOI: 10.1128/Mcb.22.11.3729-3743.2002  0.561
2002 Cervoni N, Detich N, Seo SB, Chakravarti D, Szyf M. The oncoprotein Set/TAF-1beta, an inhibitor of histone acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing. The Journal of Biological Chemistry. 277: 25026-31. PMID 11978794 DOI: 10.1074/Jbc.M202256200  0.561
2002 Seo SB, Macfarlan T, McNamara P, Hong R, Mukai Y, Heo S, Chakravarti D. Regulation of histone acetylation and transcription by nuclear protein pp32, a subunit of the INHAT complex. The Journal of Biological Chemistry. 277: 14005-10. PMID 11830591 DOI: 10.1074/Jbc.M112455200  0.806
2001 McNamara P, Seo SB, Rudic RD, Sehgal A, Chakravarti D, FitzGerald GA. Regulation of CLOCK and MOP4 by nuclear hormone receptors in the vasculature: a humoral mechanism to reset a peripheral clock. Cell. 105: 877-89. PMID 11439184 DOI: 10.1016/S0092-8674(01)00401-9  0.371
2001 Seo SB, McNamara P, Heo S, Turner A, Lane WS, Chakravarti D. Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein. Cell. 104: 119-30. PMID 11163245 DOI: 10.1016/S0092-8674(01)00196-9  0.663
1999 Chakravarti D, Ogryzko V, Kao HY, Nash A, Chen H, Nakatani Y, Evans RM. A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity. Cell. 96: 393-403. PMID 10025405 DOI: 10.1016/S0092-8674(00)80552-8  0.577
1997 Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell. 90: 569-80. PMID 9267036 DOI: 10.1016/S0092-8674(00)80516-4  0.554
1997 Nagy L, Kao HY, Chakravarti D, Lin RJ, Hassig CA, Ayer DE, Schreiber SL, Evans RM. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell. 89: 373-80. PMID 9150137 DOI: 10.1016/S0092-8674(00)80218-4  0.572
1996 Chakravarti D, LaMorte VJ, Nelson MC, Nakajima T, Schulman IG, Juguilon H, Montminy M, Evans RM. Role of CBP/P300 in nuclear receptor signalling. Nature. 383: 99-103. PMID 8779723 DOI: 10.1038/383099A0  0.425
1995 Schulman IG, Chakravarti D, Juguilon H, Romo A, Evans RM. Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation Proceedings of the National Academy of Sciences of the United States of America. 92: 8288-8292. PMID 7667283 DOI: 10.1073/Pnas.92.18.8288  0.413
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