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Rami N. Hannoush, Ph.D. - Publications

Affiliations: 
2003 McGill University, Montreal, QC, Canada 
Area:
Biochemistry, Molecular Biology
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hansen S, Nile A, Mehta S, Fuhrmann J, Hannoush RN. Lead optimization yields high affinity Frizzled 7-targeting peptides that modulate Clostridium difficile toxin B pathogenicity in epithelial cells. Journal of Medicinal Chemistry. PMID 31429553 DOI: 10.1021/Acs.Jmedchem.9B00500  0.323
2019 Nile AH, Hannoush RN. Probing Interaction of Lipid-Modified Wnt Protein and Its Receptors by ELISA. Methods in Molecular Biology (Clifton, N.J.). 2009: 217-225. PMID 31152407 DOI: 10.1007/978-1-4939-9532-5_17  0.408
2019 Gao X, De Mazière A, Iaea DB, Arthur CP, Klumperman J, Ciferri C, Hannoush RN. Visualizing the cellular route of entry of a cystine-knot peptide with Xfect transfection reagent by electron microscopy. Scientific Reports. 9: 6907. PMID 31061420 DOI: 10.1038/S41598-019-43285-5  0.324
2019 Nile AH, Hannoush RN. Fatty acid recognition in the Frizzled receptor family. The Journal of Biological Chemistry. 294: 726-736. PMID 30530496 DOI: 10.1074/Jbc.Rev118.005205  0.431
2018 Nile AH, de Sousa E Melo F, Mukund S, Piskol R, Hansen S, Zhou L, Zhang Y, Fu Y, Gogol EB, Kömüves LG, Modrusan Z, Angers S, Franke Y, Koth C, Fairbrother WJ, ... ... Hannoush RN, et al. A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nature Chemical Biology. PMID 29632413 DOI: 10.1038/S41589-018-0035-2  0.394
2017 Gao X, Hannoush RN. A Decade of Click Chemistry in Protein Palmitoylation: Impact on Discovery and New Biology. Cell Chemical Biology. PMID 29290622 DOI: 10.1016/J.Chembiol.2017.12.002  0.367
2017 Nile AH, Mukund S, Stanger K, Wang W, Hannoush RN. Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding. Proceedings of the National Academy of Sciences of the United States of America. PMID 28377511 DOI: 10.1073/Pnas.1618293114  0.363
2016 Gao X, Stanger K, Kaluarachchi H, Maurer T, Ciepla P, Chalouni C, Franke Y, Hannoush RN. Cellular uptake of a cystine-knot peptide and modulation of its intracellular trafficking. Scientific Reports. 6: 35179. PMID 27734922 DOI: 10.1038/Srep35179  0.318
2016 Gao X, Hannoush RN. Visualizing Wnt Palmitoylation in Single Cells. Methods in Molecular Biology (Clifton, N.J.). 1481: 1-9. PMID 27590146 DOI: 10.1007/978-1-4939-6393-5_1  0.391
2016 Nile AH, Hannoush RN. Fatty acylation of Wnt proteins. Nature Chemical Biology. 12: 60-9. PMID 26784846 DOI: 10.1038/Nchembio.2005  0.418
2015 Noland CL, Gierke S, Schnier PD, Murray J, Sandoval WN, Sagolla M, Dey A, Hannoush RN, Fairbrother WJ, Cunningham CN. Palmitoylation of TEAD Transcription Factors Is Required for Their Stability and Function in Hippo Pathway Signaling. Structure (London, England : 1993). PMID 26724994 DOI: 10.1016/J.Str.2015.11.005  0.377
2015 Hannoush RN. Synthetic protein lipidation. Current Opinion in Chemical Biology. 28: 39-46. PMID 26080277 DOI: 10.1016/J.Cbpa.2015.05.025  0.373
2015 Sharpe HJ, Wang W, Hannoush RN, de Sauvage FJ. Regulation of the oncoprotein Smoothened by small molecules. Nature Chemical Biology. 11: 246-55. PMID 25785427 DOI: 10.1038/Nchembio.1776  0.396
2015 Dijksterhuis JP, Baljinnyam B, Stanger K, Sercan HO, Ji Y, Andres O, Rubin JS, Hannoush RN, Schulte G. Systematic mapping of WNT-FZD protein interactions reveals functional selectivity by distinct WNT-FZD pairs. The Journal of Biological Chemistry. 290: 6789-98. PMID 25605717 DOI: 10.1074/Jbc.M114.612648  0.379
2014 Miranda M, Galli LM, Enriquez M, Szabo LA, Gao X, Hannoush RN, Burrus LW. Identification of the WNT1 residues required for palmitoylation by Porcupine. Febs Letters. 588: 4815-24. PMID 25451226 DOI: 10.1016/J.Febslet.2014.11.016  0.369
2014 Gao X, Hannoush RN. Single-cell in situ imaging of palmitoylation in fatty-acylated proteins. Nature Protocols. 9: 2607-23. PMID 25299157 DOI: 10.1038/Nprot.2014.179  0.378
2014 Gao X, Hannoush RN. Method for cellular imaging of palmitoylated proteins with clickable probes and proximity ligation applied to Hedgehog, tubulin, and Ras. Journal of the American Chemical Society. 136: 4544-50. PMID 24588349 DOI: 10.1021/Ja410068G  0.35
2014 Gao X, Hannoush RN. Single-cell imaging of Wnt palmitoylation by the acyltransferase porcupine. Nature Chemical Biology. 10: 61-8. PMID 24292069 DOI: 10.1038/Nchembio.1392  0.397
2013 Huang X, McGann JC, Liu BY, Hannoush RN, Lill JR, Pham V, Newton K, Kakunda M, Liu J, Yu C, Hymowitz SG, Hongo JA, Wynshaw-Boris A, Polakis P, Harland RM, et al. Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling. Science (New York, N.Y.). 339: 1441-5. PMID 23371553 DOI: 10.1126/Science.1232253  0.358
2013 Ciana A, Achilli C, Hannoush RN, Risso A, Balduini C, Minetti G. Freely turning over palmitate in erythrocyte membrane proteins is not responsible for the anchoring of lipid rafts to the spectrin skeleton: a study with bio-orthogonal chemical probes. Biochimica Et Biophysica Acta. 1828: 924-31. PMID 23219804 DOI: 10.1016/J.Bbamem.2012.11.029  0.334
2013 Proffitt KD, Madan B, Ke Z, Pendharkar V, Ding L, Lee MA, Hannoush RN, Virshup DM. Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer. Cancer Research. 73: 502-7. PMID 23188502 DOI: 10.1158/0008-5472.Can-12-2258  0.315
2012 Stanger K, Steffek M, Zhou L, Pozniak CD, Quan C, Franke Y, Tom J, Tam C, Krylova I, Elliott JM, Lewcock JW, Zhang Y, Murray J, Hannoush RN. Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization. Nature Chemical Biology. 8: 655-60. PMID 22683611 DOI: 10.1038/Nchembio.967  0.316
2012 Mintzer R, Ramaswamy S, Shah K, Hannoush RN, Pozniak CD, Cohen F, Zhao X, Plise E, Lewcock JW, Heise CE. A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C. Plos One. 7: e30376. PMID 22253931 DOI: 10.1371/Journal.Pone.0030376  0.321
2012 Hannoush RN. Profiling cellular myristoylation and palmitoylation using ω-alkynyl fatty acids. Methods in Molecular Biology (Clifton, N.J.). 800: 85-94. PMID 21964784 DOI: 10.1007/978-1-61779-349-3_7  0.341
2011 Hannoush RN. Development of chemical probes for biochemical detection and cellular imaging of myristoylated and palmitoylated proteins. Current Protocols in Chemical Biology. 3: 15-26. PMID 23836586 DOI: 10.1002/9780470559277.Ch100143  0.364
2011 Gao X, Arenas-Ramirez N, Scales SJ, Hannoush RN. Membrane targeting of palmitoylated Wnt and Hedgehog revealed by chemical probes. Febs Letters. 585: 2501-6. PMID 21740904 DOI: 10.1016/J.Febslet.2011.06.033  0.384
2010 Gong Y, Bourhis E, Chiu C, Stawicki S, DeAlmeida VI, Liu BY, Phamluong K, Cao TC, Carano RA, Ernst JA, Solloway M, Rubinfeld B, Hannoush RN, Wu Y, Polakis P, et al. Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies. Plos One. 5: e12682. PMID 20856934 DOI: 10.1371/Journal.Pone.0012682  0.356
2010 Hannoush RN, Sun J. The chemical toolbox for monitoring protein fatty acylation and prenylation. Nature Chemical Biology. 6: 498-506. PMID 20559317 DOI: 10.1038/Nchembio.388  0.373
2010 Bourhis E, Tam C, Franke Y, Bazan JF, Ernst J, Hwang J, Costa M, Cochran AG, Hannoush RN. Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6. The Journal of Biological Chemistry. 285: 9172-9. PMID 20093360 DOI: 10.1074/Jbc.M109.092130  0.358
2009 Hannoush RN, Arenas-Ramirez N. Imaging the lipidome: omega-alkynyl fatty acids for detection and cellular visualization of lipid-modified proteins. Acs Chemical Biology. 4: 581-7. PMID 19505150 DOI: 10.1021/Cb900085Z  0.385
2009 Zhang Y, Appleton BA, Wiesmann C, Lau T, Costa M, Hannoush RN, Sidhu SS. Inhibition of Wnt signaling by Dishevelled PDZ peptides. Nature Chemical Biology. 5: 217-9. PMID 19252499 DOI: 10.1038/Nchembio.152  0.368
2008 Hannoush RN. Kinetics of Wnt-driven beta-catenin stabilization revealed by quantitative and temporal imaging. Plos One. 3: e3498. PMID 18941539 DOI: 10.1371/Journal.Pone.0003498  0.303
2004 Hannoush RN, Min KL, Damha MJ. Diversity-oriented solid-phase synthesis and biological evaluation of oligonucleotide hairpins as HIV-1 RT RNase H inhibitors. Nucleic Acids Research. 32: 6164-75. PMID 15570067 DOI: 10.1093/Nar/Gkh948  0.303
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