| Year |
Citation |
Score |
| 2021 |
Matuszyk MM, Garwood CJ, Ferraiuolo L, Simpson JE, Staniforth RA, Wharton SB. Biological and methodological complexities of beta-amyloid peptide: Implications for Alzheimer's disease research. Journal of Neurochemistry. PMID 34767256 DOI: 10.1111/jnc.15538 |
0.437 |
|
| 2020 |
de Matos AM, Blázquez-Sánchez MT, Bento-Oliveira A, de Almeida R, Nunes RS, LOpes P, Machuqueiro M, Cristovão J, Gomes CM, Souza CS, El Idrissi IG, Colabufo NA, Diniz A, Marcelo F, Oliveira MC, ... ... Garwood C, et al. Glucosylpolyphenols as inhibitors of Aβ-induced Fyn kinase activation and Tau phosphorylation: synthesis, membrane permeability, and exploratory target assessment within the scope of type 2 diabetes and Alzheimer's disease. Journal of Medicinal Chemistry. PMID 32959649 DOI: 10.1021/Acs.Jmedchem.0C00841 |
0.463 |
|
| 2020 |
Chambers A, Bury JJ, Minett T, Richardson CD, Brayne C, Ince PG, Shaw PJ, Garwood CJ, Heath PR, Simpson JE, Matthews FE, Wharton SB. Advanced Glycation End Product Formation in Human Cerebral Cortex Increases With Alzheimer-Type Neuropathologic Changes but Is Not Independently Associated With Dementia in a Population-Derived Aging Brain Cohort. Journal of Neuropathology and Experimental Neurology. PMID 32766675 DOI: 10.1093/Jnen/Nlaa064 |
0.439 |
|
| 2020 |
Fadul MM, Garwood CJ, Waller R, Garrett N, Heath PR, Matthews FE, Brayne C, Wharton SB, Simpson JE. NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain. International Journal of Molecular Sciences. 21. PMID 31947996 DOI: 10.3390/ijms21010340 |
0.377 |
|
| 2019 |
Vazquez-Villaseñor I, Garwood CJ, Heath PR, Simpson JE, Ince PG, Wharton SB. Expression of p16 and p21 in the frontal association cortex of ALS/MND brains suggest neuronal cell cycle dysregulation and astrocyte senescence in early stages of the disease. Neuropathology and Applied Neurobiology. PMID 31077599 DOI: 10.1111/nan.12559 |
0.349 |
|
| 2019 |
Matos AM, Man T, Idrissi I, Souza CC, Mead E, Dunbar C, Wolak J, Oliveira MC, Evans D, Grayson J, Partridge B, Garwood C, Ning K, Sharman G, Chen B, et al. Discovery of N-methylpiperazinyl flavones as a novel class of compounds with therapeutic potential against Alzheimer’s disease: synthesis, binding affinity towards amyloid β oligomers (Aβo) and ability to disrupt Aβo-PrPC interactions Pure and Applied Chemistry. 91: 1107-1136. DOI: 10.1515/Pac-2019-0114 |
0.326 |
|
| 2018 |
Waller R, Murphy M, Garwood CJ, Jennings L, Heath PR, Chambers A, Matthews FE, Brayne C, Ince PG, Wharton SB, Simpson JE. Metallothionein-I/II expression associates with the astrocyte DNA damage response and not Alzheimer-type pathology in the aging brain. Glia. PMID 30098078 DOI: 10.1002/glia.23465 |
0.307 |
|
| 2018 |
Ratcliffe LE, Vázquez Villaseñor I, Jennings L, Heath PR, Mortiboys H, Schwartzentruber A, Karyka E, Simpson JE, Ince PG, Garwood CJ, Wharton SB. Loss of IGF1R in Human Astrocytes Alters Complex I Activity and Support for Neurons. Neuroscience. PMID 30056117 DOI: 10.1016/j.neuroscience.2018.07.029 |
0.32 |
|
| 2016 |
Garwood CJ, Ratcliffe LE, Simpson JE, Heath PR, Ince PG, Wharton SB. Review: Astrocytes in Alzheimer's disease and other age-associated dementias; a supporting player with a central role. Neuropathology and Applied Neurobiology. PMID 27442752 DOI: 10.1111/nan.12338 |
0.423 |
|
| 2015 |
Simpson JE, Ince PG, Minett T, Matthews FE, Heath PR, Shaw PJ, Goodall E, Garwood CJ, Ratcliffe LE, Brayne C, Rattray M, Wharton SB. Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology. Neuropathology and Applied Neurobiology. PMID 26095650 DOI: 10.1111/nan.12252 |
0.302 |
|
| 2015 |
Mathur R, Ince PG, Minett T, Garwood CJ, Shaw PJ, Matthews FE, Brayne C, Simpson JE, Wharton SB. A reduced astrocyte response to β-amyloid plaques in the ageing brain associates with cognitive impairment. Plos One. 10: e0118463. PMID 25707004 DOI: 10.1371/journal.pone.0118463 |
0.342 |
|
| 2015 |
Simpson JE, Ince PG, Matthews FE, Shaw PJ, Heath PR, Brayne C, Garwood C, Higginbottom A, Wharton SB. A neuronal DNA damage response is detected at the earliest stages of Alzheimer's neuropathology and correlates with cognitive impairment in the Medical Research Council's Cognitive Function and Ageing Study ageing brain cohort. Neuropathology and Applied Neurobiology. 41: 483-96. PMID 25443110 DOI: 10.1111/Nan.12202 |
0.381 |
|
| 2014 |
Phillips EC, Croft CL, Kurbatskaya K, O'Neill MJ, Hutton ML, Hanger DP, Garwood CJ, Noble W. Astrocytes and neuroinflammation in Alzheimer's disease. Biochemical Society Transactions. 42: 1321-5. PMID 25233410 DOI: 10.1042/Bst20140155 |
0.702 |
|
| 2014 |
Atherton J, Kurbatskaya K, Bondulich M, Croft CL, Garwood CJ, Chhabra R, Wray S, Jeromin A, Hanger DP, Noble W. Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer's disease. Aging Cell. 13: 49-59. PMID 23919677 DOI: 10.1111/Acel.12148 |
0.691 |
|
| 2014 |
Phillips EC, Garwood CJ, Hanger DP, Noble W. P1-116: ASTROCYTE ACTIVATION INFLUENCES THE DEVELOPMENT OF TAUOPATHY Alzheimer's & Dementia. 10: P343-P343. DOI: 10.1016/J.Jalz.2014.05.353 |
0.501 |
|
| 2013 |
Garwood C, Faizullabhoy A, Wharton SB, Ince PG, Heath PR, Shaw PJ, Baxter L, Gelsthorpe C, Forster G, Matthews FE, Brayne C, Simpson JE. Calcium dysregulation in relation to Alzheimer-type pathology in the ageing brain. Neuropathology and Applied Neurobiology. 39: 788-99. PMID 23421725 DOI: 10.1111/Nan.12033 |
0.469 |
|
| 2011 |
Viggars AP, Wharton SB, Simpson JE, Matthews FE, Brayne C, Savva GM, Garwood C, Drew D, Shaw PJ, Ince PG. Alterations in the blood brain barrier in ageing cerebral cortex in relationship to Alzheimer-type pathology: a study in the MRC-CFAS population neuropathology cohort. Neuroscience Letters. 505: 25-30. PMID 21970975 DOI: 10.1016/J.Neulet.2011.09.049 |
0.392 |
|
| 2011 |
Simpson JE, Ince PG, Shaw PJ, Heath PR, Raman R, Garwood CJ, Gelsthorpe C, Baxter L, Forster G, Matthews FE, Brayne C, Wharton SB. Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer's pathology and APOE genotype. Neurobiology of Aging. 32: 1795-807. PMID 21705112 DOI: 10.1016/J.Jalz.2011.05.1596 |
0.486 |
|
| 2011 |
Garwood CJ, Pooler AM, Atherton J, Hanger DP, Noble W. Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture. Cell Death & Disease. 2: e167. PMID 21633390 DOI: 10.1038/Cddis.2011.50 |
0.683 |
|
| 2010 |
Garwood CJ, Cooper JD, Hanger DP, Noble W. Anti-inflammatory impact of minocycline in a mouse model of tauopathy. Frontiers in Psychiatry. 1: 136. PMID 21423446 DOI: 10.3389/Fpsyt.2010.00136 |
0.653 |
|
| 2010 |
Garwood CJ, Hanger DP, Noble W. P1-315: Minocycline-mediated protection from Aβ is mediated primarily by suppression of astrocytic inflammatory responses Alzheimer's & Dementia. 6: S264-S265. DOI: 10.1016/J.Jalz.2010.05.868 |
0.574 |
|
| 2009 |
Noble W, Garwood CJ, Hanger DP. Minocycline as a potential therapeutic agent in neurodegenerative disorders characterised by protein misfolding. Prion. 3: 78-83. PMID 19458490 DOI: 10.4161/Pri.3.2.8820 |
0.541 |
|
| 2009 |
Noble W, Garwood C, Stephenson J, Kinsey AM, Hanger DP, Anderton BH. Minocycline reduces the development of abnormal tau species in models of Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 739-50. PMID 19001528 DOI: 10.1096/Fj.08-113795 |
0.69 |
|
| 2008 |
Noble W, Garwood C, Hanger DP, Anderton BH. P3-342: Amyloid-mediated NCX3 cleavage by calpain is an early and toxic event Alzheimer's & Dementia. 4: T622-T622. DOI: 10.1016/J.Jalz.2008.05.1911 |
0.593 |
|
| 2008 |
Garwood CJ, Anderton BH, Hanger DP, Noble W. P2-381: Minocycline reduces caspase-3 activation and prevents cleavage and aggregation of Tau in vivo Alzheimer's & Dementia. 4: T484-T484. DOI: 10.1016/J.Jalz.2008.05.1459 |
0.575 |
|
| 2007 |
Kelleher I, Garwood C, Hanger DP, Anderton BH, Noble W. Kinase activities increase during the development of tauopathy in htau mice. Journal of Neurochemistry. 103: 2256-67. PMID 17908241 DOI: 10.1111/J.1471-4159.2007.04930.X |
0.609 |
|
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