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Stéphane Angers - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Wnt signalling, cell polarity
Website:
http://phm.utoronto.ca/angers/

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Blondel-Tepaz E, Leverve M, Sokrat B, Paradis JS, Kosic M, Saha K, Auffray C, Lima-Fernandes E, Zamborlini A, Poupon A, Gaboury L, Findlay J, Baillie GS, Enslen H, Bouvier M, ... Angers S, et al. The RanBP2/RanGAP1-SUMO complex gates β-arrestin2 nuclear entry to regulate the Mdm2-p53 signaling axis. Oncogene. PMID 33649538 DOI: 10.1038/s41388-021-01704-w  0.709
2020 Aubert L, Nandagopal N, Steinhart Z, Lavoie G, Nourreddine S, Berman J, Saba-El-Leil MK, Papadopoli D, Lin S, Hart T, Macleod G, Topisirovic I, Gaboury L, Fahrni CJ, Schramek D, ... ... Angers S, et al. Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer. Nature Communications. 11: 3701. PMID 32709883 DOI: 10.1038/S41467-020-17549-Y  0.328
2020 Ma W, Chen M, Kang H, Steinhart Z, Angers S, He X, Kirschner MW. Single-molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32601235 DOI: 10.1073/Pnas.1910547117  0.34
2020 Cao WX, Kabelitz S, Gupta M, Yeung E, Lin S, Rammelt C, Ihling C, Pekovic F, Low TCH, Siddiqui NU, Cheng MHK, Angers S, Smibert CA, Wühr M, Wahle E, et al. Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cell Reports. 31: 107783. PMID 32579915 DOI: 10.1016/J.Celrep.2020.107783  0.322
2020 Wang Z, Xia F, Labib M, Ahmadi M, Chen H, Das J, Ahmed SU, Angers S, Sargent EH, Kelley SO. Nanostructured Architectures Promote the Mesenchymal-Epithelial Transition for Invasive Cells. Acs Nano. PMID 32369335 DOI: 10.1021/Acsnano.9B07350  0.345
2020 Mis M, O'Brien S, Steinhart Z, Lin S, Hart T, Moffat J, Angers S. IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers. The Journal of Cell Biology. 219. PMID 31881079 DOI: 10.1083/Jcb.201903017  0.429
2019 Mair B, Aldridge PM, Atwal RS, Philpott D, Zhang M, Masud SN, Labib M, Tong AHY, Sargent EH, Angers S, Moffat J, Kelley SO. High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting. Nature Biomedical Engineering. PMID 31548591 DOI: 10.1038/S41551-019-0454-8  0.333
2019 Tao Y, Mis M, Blazer L, Ustav M, Steinhart Z, Chidiac R, Kubarakos E, O'Brien S, Wang X, Jarvik N, Patel N, Adams J, Moffat J, Angers S, Sidhu SS. Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice. Elife. 8. PMID 31452509 DOI: 10.7554/Elife.46134  0.453
2019 Raman S, Beilschmidt M, To M, Lin K, Lui F, Jmeian Y, Ng M, Fernandez M, Fu Y, Mascall K, Duque A, Wang X, Pan G, Angers S, Moffat J, et al. Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies. Proceedings of the National Academy of Sciences of the United States of America. PMID 30894493 DOI: 10.1073/Pnas.1817246116  0.351
2019 Rajakulendran N, Rowland KJ, Selvadurai HJ, Ahmadi M, Park NI, Naumenko S, Dolma S, Ward RJ, So M, Lee L, MacLeod G, Pasiliao C, Brandon C, Clarke ID, Cusimano MD, ... ... Angers S, et al. Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells. Genes & Development. PMID 30842215 DOI: 10.1101/Gad.321968.118  0.361
2019 Okeke K, Angers S, Bouvier M, Michel MC. Agonist-induced desensitisation of β -adrenoceptors: where, when and how? British Journal of Pharmacology. PMID 30809805 DOI: 10.1111/Bph.14633  0.542
2019 Magomedova L, Tiefenbach J, Zilberman E, Le Billan F, Voisin V, Saikali M, Boivin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu C, Jeyasuria P, Bader GD, ... ... Angers S, et al. ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development. Nucleic Acids Research. PMID 30698747 DOI: 10.1093/Nar/Gkz010  0.408
2019 Bozek D, MacLeod G, Hao X, Rajakulendran N, Ahmadi M, Dirks P, Angers S, Luchman A, Weiss S. STEM-21. INVESTIGATING DOT1L AS AN EPIGENETIC VULNERABILITY IN BRAIN TUMOR STEM CELLS Neuro-Oncology. 21: vi238-vi238. DOI: 10.1093/Neuonc/Noz175.994  0.302
2019 MacLeod G, Angers S, Dirks P, Rajakulendran N, Ahmadi M, Bozek D, Luchman A, Weiss S. GENE-31. IDENTIFICATION OF CORE AND CONTEXT-SPECIFIC FITNESS GENES IN GLIOBLASTOMA STEM CELLS VIA GENOME-WIDE CRISPR-Cas9 SCREENS Neuro-Oncology. 21: vi104-vi104. DOI: 10.1093/Neuonc/Noz175.433  0.314
2018 Yin WC, Satkunendran T, Mo R, Morrissy S, Zhang X, Huang ES, Uusküla-Reimand L, Hou H, Son JE, Liu W, Liu YC, Zhang J, Parker J, Wang X, Farooq H, ... ... Angers S, et al. Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma. Developmental Cell. PMID 30554998 DOI: 10.1016/J.Devcel.2018.11.015  0.329
2018 Poudineh M, Wang Z, Labib M, Ahmadi M, Zhang L, Das J, Ahmed S, Angers S, Kelley SO. Three-Dimensional Nanostructured Architectures Enable Efficient Neural Differentiation of Mesenchymal Stem Cells via Mechanotransduction. Nano Letters. PMID 30335391 DOI: 10.1021/Acs.Nanolett.8B03313  0.305
2018 Pavlovic Z, Adams JJ, Blazer LL, Gakhal AK, Jarvik N, Steinhart Z, Robitaille M, Mascall K, Pan J, Angers S, Moffat J, Sidhu SS. A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties. Mabs. PMID 30183492 DOI: 10.1080/19420862.2018.1515565  0.329
2018 Steinhart Z, Angers S. Wnt signaling in development and tissue homeostasis. Development (Cambridge, England). 145. PMID 29884654 DOI: 10.1242/Dev.146589  0.381
2018 Nile AH, de Sousa E Melo F, Mukund S, Piskol R, Hansen S, Zhou L, Zhang Y, Fu Y, Gogol EB, Kömüves LG, Modrusan Z, Angers S, Franke Y, Koth C, Fairbrother WJ, et al. A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nature Chemical Biology. PMID 29632413 DOI: 10.1038/S41589-018-0035-2  0.431
2018 Youn JY, Dunham WH, Hong SJ, Knight JDR, Bashkurov M, Chen GI, Bagci H, Rathod B, MacLeod G, Eng SWM, Angers S, Morris Q, Fabian M, Côté JF, Gingras AC. High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies. Molecular Cell. 69: 517-532.e11. PMID 29395067 DOI: 10.1016/J.Molcel.2017.12.020  0.341
2017 Sokolina K, Kittanakom S, Snider J, Kotlyar M, Maurice P, Gandía J, Benleulmi-Chaachoua A, Tadagaki K, Oishi A, Wong V, Malty RH, Deineko V, Aoki H, Amin S, Yao Z, ... ... Angers S, et al. Systematic protein-protein interaction mapping for clinically relevant human GPCRs. Molecular Systems Biology. 13: 918. PMID 28298427 DOI: 10.15252/Msb.20167430  0.593
2017 Angers S. Abstract IA06: Leveraging genome-wide CRISPR screens and synthetic lethal interactions for novel cancer therapeutics Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-Ia06  0.385
2017 MacLeod G, Rajakulendran N, Hart T, Yu H, Dirks PB, Angers S. Abstract A38: Genome-wide CRISPR-Cas9 screens reveal modulators of temozolomide sensitivity in glioblastoma Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-A38  0.31
2016 Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, ... ... Angers S, et al. Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors. Nature Medicine. PMID 27869803 DOI: 10.1038/Nm.4219  0.394
2016 Gammons MV, Rutherford TJ, Steinhart Z, Angers S, Bienz M. Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay. Journal of Cell Science. 129: 3892-3902. PMID 27744318 DOI: 10.1242/Jcs.195685  0.419
2016 Lacroix C, Fish I, Torosyan H, Parathaman P, Irwin JJ, Shoichet BK, Angers S. Identification of Novel Smoothened Ligands Using Structure-Based Docking. Plos One. 11: e0160365. PMID 27490099 DOI: 10.1371/Journal.Pone.0160365  0.373
2016 Cervenka I, Valnohova J, Bernatik O, Harnos J, Radsetoulal M, Sedova K, Hanakova K, Potesil D, Sedlackova M, Salasova A, Steinhart Z, Angers S, Schulte G, Hampl A, Zdrahal Z, et al. Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 27486244 DOI: 10.1073/Pnas.1608783113  0.372
2016 Di Sebastino AR, Fahim S, Dunn HA, Walther C, Ribeiro FM, Cregan SP, Angers S, Schmid S, Ferguson SS. Role of Spinophilin in Group I Metabotropic Glutamate Receptor Endocytosis, Signaling and Synaptic Plasticity. The Journal of Biological Chemistry. PMID 27358397 DOI: 10.1074/Jbc.M116.722355  0.38
2016 Daulat AM, Bertucci F, Audebert S, Sergé A, Finetti P, Josselin E, Castellano R, Birnbaum D, Angers S, Borg JP. PRICKLE1 Contributes to Cancer Cell Dissemination through Its Interaction with mTORC2. Developmental Cell. PMID 27184734 DOI: 10.1016/J.Devcel.2016.04.011  0.359
2016 Farin HF, Jordens I, Mosa MH, Basak O, Korving J, Tauriello DV, de Punder K, Angers S, Peters PJ, Maurice MM, Clevers H. Visualization of a short-range Wnt gradient in the intestinal stem-cell niche. Nature. PMID 26863187 DOI: 10.1038/Nature16937  0.391
2016 Chiu CW, Monat C, Robitaille M, Lacomme M, Daulat AM, Macleod G, McNeill H, Cayouette M, Angers S. SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex. Developmental Cell. 36: 50-62. PMID 26766442 DOI: 10.1016/J.Devcel.2015.12.016  0.35
2016 Dey A, Robitaille M, Remke M, Maier C, Malhotra A, Gregorieff A, Wrana JL, Taylor MD, Angers S, Kenney AM. YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells. Oncogene. PMID 26725322 DOI: 10.1038/Onc.2015.491  0.365
2016 Steinhart Z, Hart T, Sidhu S, Moffat J, Angers S. Abstract IA13: Inhibiting the Wnt pathway with selective anti-Frizzled synthetic antibodies Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-Ia13  0.46
2016 Rajakulendran N, Selvadurai H, Rowland K, Park N, Batada N, Dirks P, Angers S. Abstract B14: Wnt signaling circuits in glioblastoma multiforme Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-B14  0.425
2016 Hart T, Chandrashekhar M, Aregger M, Steinhart Z, Brown KR, Macleod G, Mis M, Zimmermann M, Fradet-Turcotte A, Sun S, Driks P, Sidhu S, Roth FP, Rissland OS, Durocher D, ... Angers S, et al. Abstract PR03: High-resolution detection of fitness genes and genotype-specific cancer vulnerabilities with CRISPR-Cas9 screens Cancer Research. 76. DOI: 10.1158/1538-7445.Fbcr15-Pr03  0.343
2015 Hart T, Chandrashekhar M, Aregger M, Steinhart Z, Brown KR, MacLeod G, Mis M, Zimmermann M, Fradet-Turcotte A, Sun S, Mero P, Dirks P, Sidhu S, Roth FP, Rissland OS, ... ... Angers S, et al. High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities. Cell. PMID 26627737 DOI: 10.1016/J.Cell.2015.11.015  0.334
2015 Jiang T, McKinley RF, McGill MA, Angers S, Harris TJ. A Par-1-Par-3-Centrosome Cell Polarity Pathway and Its Tuning for Isotropic Cell Adhesion. Current Biology : Cb. 25: 2701-2708. PMID 26455305 DOI: 10.1016/J.Cub.2015.08.063  0.308
2015 Han J, Zhang M, Froese S, Dai FF, Robitaille M, Bhattacharjee A, Huang X, Jia W, Angers S, Wheeler MB, Wei L. The Identification of Novel Protein-Protein Interactions in Liver that Affect Glucagon Receptor Activity. Plos One. 10: e0129226. PMID 26075596 DOI: 10.1371/Journal.Pone.0129226  0.392
2015 Khan SM, Min A, Gora S, Houranieh GM, Campden R, Robitaille M, Trieu P, Pétrin D, Jacobi AM, Behlke MA, Angers S, Hébert TE. Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signalling. Cellular Signalling. 27: 1597-608. PMID 25916507 DOI: 10.1016/J.Cellsig.2015.04.007  0.436
2015 Coyaud E, Mis M, Laurent EM, Dunham WH, Couzens AL, Robitaille M, Gingras AC, Angers S, Raught B. BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates. Molecular & Cellular Proteomics : McP. 14: 1781-95. PMID 25900982 DOI: 10.1074/Mcp.M114.045658  0.337
2015 Raka F, Di Sebastiano AR, Kulhawy SC, Ribeiro FM, Godin CM, Caetano FA, Angers S, Ferguson SS. Ca(2+)/calmodulin-dependent protein kinase II interacts with group I metabotropic glutamate and facilitates receptor endocytosis and ERK1/2 signaling: role of β-amyloid. Molecular Brain. 8: 21. PMID 25885040 DOI: 10.1186/S13041-015-0111-4  0.433
2015 Liu J, Lee DM, Yu CG, Angers S, Harris TJ. Stepping stone: a cytohesin adaptor for membrane cytoskeleton restraint in the syncytial Drosophila embryo. Molecular Biology of the Cell. 26: 711-25. PMID 25540427 DOI: 10.1091/Mbc.E14-11-1554  0.324
2015 Zhulyn O, Nieuwenhuis E, Liu YC, Angers S, Hui CC. Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development. Developmental Biology. 397: 191-202. PMID 25448692 DOI: 10.1016/J.Ydbio.2014.10.023  0.449
2015 Campden R, Pétrin D, Robitaille M, Audet N, Gora S, Angers S, Hébert TE. Tandem affinity purification to identify cytosolic and nuclear gβγ-interacting proteins. Methods in Molecular Biology (Clifton, N.J.). 1234: 161-84. PMID 25304356 DOI: 10.1007/978-1-4939-1755-6_14  0.377
2015 Dey A, Robitaille M, Remke M, Maier C, Malhotra A, Gregorieff A, Wrana J, Taylor M, Angers S, Kenney A. MB-02 * SONIC HEDGEHOG INDUCES YB-1 IN A YAP-DEPENDENT MANNER TO REGULATE Igf2 EXPRESSION AND PROLIFERATION IN CEREBELLAR GRANULE NEURON PROGENITORS AND MEDULLOBLASTOMA CELLS Neuro-Oncology. 17: iii20-iii20. DOI: 10.1093/Neuonc/Nov061.78  0.362
2014 Liu YC, Couzens AL, Deshwar AR, B McBroom-Cerajewski LD, Zhang X, Puviindran V, Scott IC, Gingras AC, Hui CC, Angers S. The PPFIA1-PP2A protein complex promotes trafficking of Kif7 to the ciliary tip and Hedgehog signaling. Science Signaling. 7: ra117. PMID 25492966 DOI: 10.1126/Scisignal.2005608  0.409
2014 Zhang M, Robitaille M, Showalter AD, Huang X, Liu Y, Bhattacharjee A, Willard FS, Han J, Froese S, Wei L, Gaisano HY, Angers S, Sloop KW, Dai FF, Wheeler MB. Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells. Molecular & Cellular Proteomics : McP. 13: 3049-62. PMID 25044020 DOI: 10.1074/Mcp.M114.040196  0.45
2014 Lachance V, Angers S, Parent JL. New insights in the regulation of Rab GTPases by G protein-coupled receptors. Small Gtpases. 5: e29039. PMID 24950538 DOI: 10.4161/sgtp.29039  0.391
2014 Lachance V, Degrandmaison J, Marois S, Robitaille M, Génier S, Nadeau S, Angers S, Parent JL. Ubiquitylation and activation of a Rab GTPase is promoted by a β₂AR-HACE1 complex. Journal of Cell Science. 127: 111-23. PMID 24190883 DOI: 10.1242/Jcs.132944  0.468
2014 Li ZJ, Mack SC, Mak TH, Angers S, Taylor MD, Hui CC. Evasion of p53 and G2/M checkpoints are characteristic of Hh-driven basal cell carcinoma. Oncogene. 33: 2674-80. PMID 23752195 DOI: 10.1038/Onc.2013.212  0.357
2013 Roy SJ, Glazkova I, Fréchette L, Iorio-Morin C, Binda C, Pétrin D, Trieu P, Robitaille M, Angers S, Hébert TE, Parent JL. Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability. Molecular Endocrinology (Baltimore, Md.). 27: 1245-66. PMID 23798571 DOI: 10.1210/Me.2013-1091  0.487
2013 Belotti E, Polanowska J, Daulat AM, Audebert S, Thomé V, Lissitzky JC, Lembo F, Blibek K, Omi S, Lenfant N, Gangar A, Montcouquiol M, Santoni MJ, Sebbagh M, Aurrand-Lions M, ... Angers S, et al. The human PDZome: a gateway to PSD95-Disc large-zonula occludens (PDZ)-mediated functions. Molecular & Cellular Proteomics : McP. 12: 2587-603. PMID 23722234 DOI: 10.1074/Mcp.O112.021022  0.364
2013 Ahmed SM, Angers S. Emerging non-canonical functions for heterotrimeric G proteins in cellular signaling. Journal of Receptor and Signal Transduction Research. 33: 177-83. PMID 23721574 DOI: 10.3109/10799893.2013.795972  0.408
2013 Lam VM, Beerepoot P, Angers S, Salahpour A. A novel assay for measurement of membrane-protein surface expression using a β-lactamase. Traffic (Copenhagen, Denmark). 14: 778-84. PMID 23574269 DOI: 10.1111/Tra.12073  0.689
2013 Hayes M, Naito M, Daulat A, Angers S, Ciruna B. Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development. Development (Cambridge, England). 140: 1807-18. PMID 23533179 DOI: 10.1242/Dev.090183  0.428
2013 Agarwal M, Nitta R, Dovat S, Li G, Arita H, Narita Y, Fukushima S, Tateishi K, Matsushita Y, Yoshida A, Miyakita Y, Ohno M, Collins VP, Kawahara N, Shibui S, ... ... Angers S, et al. CELL BIOLOGY AND SIGNALING Neuro-Oncology. 15: iii12-iii31. DOI: 10.1093/Neuonc/Not174  0.35
2012 Ahmed SM, Thériault BL, Uppalapati M, Chiu CW, Gallie BL, Sidhu SS, Angers S. KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression. The Journal of Cell Biology. 199: 951-67. PMID 23209302 DOI: 10.1083/Jcb.201206051  0.38
2012 Bao R, Christova T, Song S, Angers S, Yan X, Attisano L. Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells. Plos One. 7: e48670. PMID 23144924 DOI: 10.1371/Journal.Pone.0048670  0.389
2012 Liu L, Aerbajinai W, Ahmed SM, Rodgers GP, Angers S, Parent CA. Radil controls neutrophil adhesion and motility through β2-integrin activation. Molecular Biology of the Cell. 23: 4751-65. PMID 23097489 DOI: 10.1091/Mbc.E12-05-0408  0.325
2012 Lee AH, Hurley B, Felsensteiner C, Yea C, Ckurshumova W, Bartetzko V, Wang PW, Quach V, Lewis JD, Liu YC, Börnke F, Angers S, Wilde A, Guttman DS, Desveaux D. A bacterial acetyltransferase destroys plant microtubule networks and blocks secretion. Plos Pathogens. 8: e1002523. PMID 22319451 DOI: 10.1371/Journal.Ppat.1002523  0.301
2012 Anastas JN, Biechele TL, Robitaille M, Muster J, Allison KH, Angers S, Moon RT. A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression. Oncogene. 31: 3696-708. PMID 22179838 DOI: 10.1038/Onc.2011.528  0.751
2012 Daulat AM, Luu O, Sing A, Zhang L, Wrana JL, McNeill H, Winklbauer R, Angers S. Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation. Molecular and Cellular Biology. 32: 173-85. PMID 22037766 DOI: 10.1128/Mcb.06320-11  0.392
2011 Tharmalingam S, Daulat AM, Antflick JE, Ahmed SM, Nemeth EF, Angers S, Conigrave AD, Hampson DR. Calcium-sensing receptor modulates cell adhesion and migration via integrins. The Journal of Biological Chemistry. 286: 40922-33. PMID 21969374 DOI: 10.1074/Jbc.M111.265454  0.442
2011 Ahmed SM, Daulat AM, Angers S. Tandem affinity purification and identification of heterotrimeric g protein-associated proteins. Methods in Molecular Biology (Clifton, N.J.). 756: 357-70. PMID 21870239 DOI: 10.1007/978-1-61779-160-4_22  0.41
2011 Hui CC, Angers S. Gli proteins in development and disease. Annual Review of Cell and Developmental Biology. 27: 513-37. PMID 21801010 DOI: 10.1146/Annurev-Cellbio-092910-154048  0.417
2011 Lui TT, Lacroix C, Ahmed SM, Goldenberg SJ, Leach CA, Daulat AM, Angers S. The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling. Molecular and Cellular Biology. 31: 2053-65. PMID 21383061 DOI: 10.1128/Mcb.01094-10  0.42
2010 Pisterzi LF, Jansma DB, Georgiou J, Woodside MJ, Chou JT, Angers S, Raicu V, Wells JW. Oligomeric size of the m2 muscarinic receptor in live cells as determined by quantitative fluorescence resonance energy transfer. The Journal of Biological Chemistry. 285: 16723-38. PMID 20304928 DOI: 10.1074/Jbc.M109.069443  0.352
2010 Ahmed SM, Daulat AM, Meunier A, Angers S. G protein betagamma subunits regulate cell adhesion through Rap1a and its effector Radil. The Journal of Biological Chemistry. 285: 6538-51. PMID 20048162 DOI: 10.1074/Jbc.M109.069948  0.465
2009 Fernandez-L A, Northcott PA, Dalton J, Fraga C, Ellison D, Angers S, Taylor MD, Kenney AM. YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. Genes & Development. 23: 2729-41. PMID 19952108 DOI: 10.1101/Gad.1824509  0.381
2009 Angers S, Moon RT. Proximal events in Wnt signal transduction. Nature Reviews. Molecular Cell Biology. 10: 468-77. PMID 19536106 DOI: 10.1038/Nrm2717  0.664
2009 Louie SH, Yang XY, Conrad WH, Muster J, Angers S, Moon RT, Cheyette BN. Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1. Plos One. 4: e4310. PMID 19183803 DOI: 10.1371/Journal.Pone.0004310  0.814
2009 Pisterzi LF, Jansma DB, Georgiou J, Woodside MJ, Chou JT, Angers S, Raicu V, Wells JW. Oligomeric Size of the M2 Muscarinic Receptor in the Plasma Membrane of Live Cells as Determined by Quantitative FRET Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.781  0.312
2008 Angers S. Proteomic analyses of protein complexes in the Wnt pathway. Methods in Molecular Biology (Clifton, N.J.). 468: 223-30. PMID 19099258 DOI: 10.1007/978-1-59745-249-6_17  0.408
2008 Major MB, Roberts BS, Berndt JD, Marine S, Anastas J, Chung N, Ferrer M, Yi X, Stoick-Cooper CL, von Haller PD, Kategaya L, Chien A, Angers S, MacCoss M, Cleary MA, et al. New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening. Science Signaling. 1: ra12. PMID 19001663 DOI: 10.1126/Scisignal.2000037  0.783
2007 Ma AW, Redka DS, Pisterzi LF, Angers S, Wells JW. Recovery of oligomers and cooperativity when monomers of the M2 muscarinic cholinergic receptor are reconstituted into phospholipid vesicles. Biochemistry. 46: 7907-27. PMID 17552496 DOI: 10.1021/Bi6026105  0.397
2007 Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT. Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling. Science (New York, N.Y.). 316: 1043-6. PMID 17510365 DOI: 10.1126/Science/1141515  0.798
2006 Angers S, Li T, Yi X, MacCoss MJ, Moon RT, Zheng N. Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Nature. 443: 590-3. PMID 16964240 DOI: 10.1038/Nature05175  0.539
2006 Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT. The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation. Nature Cell Biology. 8: 348-57. PMID 16547521 DOI: 10.1038/Ncb1381  0.8
2006 Barbas D, Zappulla JP, Angers S, Bouvier M, Mohamed HA, Byrne JH, Castellucci VF, DesGroseillers L. An aplysia dopamine1-like receptor: molecular and functional characterization. Journal of Neurochemistry. 96: 414-27. PMID 16336222 DOI: 10.1111/J.1471-4159.2005.03561.X  0.563
2004 Salahpour A, Angers S, Mercier JF, Lagacé M, Marullo S, Bouvier M. Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting. The Journal of Biological Chemistry. 279: 33390-7. PMID 15155738 DOI: 10.1074/Jbc.M403363200  0.824
2003 Azzi M, Charest PG, Angers S, Rousseau G, Kohout T, Bouvier M, Piñeyro G. Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America. 100: 11406-11. PMID 13679574 DOI: 10.1073/Pnas.1936664100  0.799
2002 Bertrand L, Parent S, Caron M, Legault M, Joly E, Angers S, Bouvier M, Brown M, Houle B, Ménard L. The BRET2/arrestin assay in stable recombinant cells: a platform to screen for compounds that interact with G protein-coupled receptors (GPCRS). Journal of Receptor and Signal Transduction Research. 22: 533-41. PMID 12503639 DOI: 10.1081/Rrs-120014619  0.813
2002 Mercier JF, Salahpour A, Angers S, Breit A, Bouvier M. Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer. The Journal of Biological Chemistry. 277: 44925-31. PMID 12244098 DOI: 10.1074/Jbc.M205767200  0.802
2002 Issafras H, Angers S, Bulenger S, Blanpain C, Parmentier M, Labbé-Jullié C, Bouvier M, Marullo S. Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors. The Journal of Biological Chemistry. 277: 34666-73. PMID 12089144 DOI: 10.1074/Jbc.M202386200  0.593
2002 Ayoub MA, Couturier C, Lucas-Meunier E, Angers S, Fossier P, Bouvier M, Jockers R. Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer. The Journal of Biological Chemistry. 277: 21522-8. PMID 11940583 DOI: 10.1074/Jbc.M200729200  0.587
2002 Barbas D, Zappulla JP, Angers S, Bouvier M, Castellucci VF, DesGroseillers L. Functional characterization of a novel serotonin receptor (5-HTap2) expressed in the CNS of Aplysia californica. Journal of Neurochemistry. 80: 335-45. PMID 11902124 DOI: 10.1046/J.0022-3042.2001.00703.X  0.588
2002 Angers S, Salahpour A, Bouvier M. Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function. Annual Review of Pharmacology and Toxicology. 42: 409-35. PMID 11807178 DOI: 10.1146/Annurev.Pharmtox.42.091701.082314  0.773
2001 Angers S, Salahpour A, Bouvier M. Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells. Life Sciences. 68: 2243-50. PMID 11358333 DOI: 10.1016/S0024-3205(01)01012-8  0.788
2000 Angers S, Bouvier M. Reply: beyond receptor dimerization Trends in Pharmacological Sciences. 21: 326. PMID 10973077 DOI: 10.1016/S0165-6147(00)01518-2  0.604
2000 Salahpour A, Angers S, Bouvier M. Functional significance of oligomerization of G-protein-coupled receptors. Trends in Endocrinology and Metabolism: Tem. 11: 163-8. PMID 10856916 DOI: 10.1016/S1043-2760(00)00260-5  0.766
2000 Morello JP, Salahpour A, Laperrière A, Bernier V, Arthus MF, Lonergan M, Petäjä-Repo U, Angers S, Morin D, Bichet DG, Bouvier M. Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants. The Journal of Clinical Investigation. 105: 887-95. PMID 10749568 DOI: 10.1172/Jci8688  0.76
2000 Angers S, Salahpour A, Joly E, Hilairet S, Chelsky D, Dennis M, Bouvier M. Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). Proceedings of the National Academy of Sciences of the United States of America. 97: 3684-9. PMID 10725388 DOI: 10.1073/Pnas.97.7.3684  0.818
1999 Jockers R, Angers S, Da Silva A, Benaroch P, Strosberg AD, Bouvier M, Marullo S. Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis. The Journal of Biological Chemistry. 274: 28900-8. PMID 10506134 DOI: 10.1074/Jbc.274.41.28900  0.65
1999 Bouvier M, Angers S. Nouveaux échafaudages protéiques modulaires pour les récepteurs couplés aux protéines G. MéDecine/Sciences. 15: 741. DOI: 10.4267/10608/1423  0.416
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