Javier F. Caceres - Publications

Affiliations: 
University of Edinburgh, Edinburgh, Scotland, United Kingdom 
Area:
mRNA splicing
Website:
http://www.hgu.mrc.ac.uk/Users/Javier.Caceres/

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Melero R, Hug N, Lopez-Perrote A, Yamashita A, Caceres JF, Llorca O. The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation Nature Communications. 7. DOI: 10.1038/ncomms10585  0.48
2015 Casadio A, Longman D, Hug N, Delavaine L, Vallejos Baier R, Alonso CR, Cáceres JF. Identification and characterization of novel factors that act in the nonsense-mediated mRNA decay pathway in nematodes, flies and mammals. Embo Reports. 16: 71-8. PMID 25452588 DOI: 10.15252/embr.201439183  0.48
2014 Heras SR, Macias S, Cáceres JF, Garcia-Perez JL. Control of mammalian retrotransposons by cellular RNA processing activities. Mobile Genetic Elements. 4: e28439. PMID 25346866 DOI: 10.4161/mge.28439  0.64
2014 Hug N, Cáceres JF. The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex. Cell Reports. 8: 1845-56. PMID 25220460 DOI: 10.1016/j.celrep.2014.08.020  0.64
2014 Maslon MM, Heras SR, Bellora N, Eyras E, Cáceres JF. The translational landscape of the splicing factor SRSF1 and its role in mitosis. Elife. e02028. PMID 24842991 DOI: 10.7554/eLife.02028  0.64
2013 Gromak N, Dienstbier M, Macias S, Plass M, Eyras E, Cáceres JF, Proudfoot NJ. Drosha regulates gene expression independently of RNA cleavage function. Cell Reports. 5: 1499-510. PMID 24360955 DOI: 10.1016/j.celrep.2013.11.032  0.48
2013 Heras SR, Macias S, Plass M, Fernandez N, Cano D, Eyras E, Garcia-Perez JL, Cáceres JF. The Microprocessor controls the activity of mammalian retrotransposons. Nature Structural & Molecular Biology. 20: 1173-81. PMID 23995758 DOI: 10.1038/nsmb.2658  0.64
2013 Macias S, Cordiner RA, Cáceres JF. Cellular functions of the microprocessor. Biochemical Society Transactions. 41: 838-43. PMID 23863141 DOI: 10.1042/BST20130011  0.64
2013 Longman D, Hug N, Keith M, Anastasaki C, Patton EE, Grimes G, Cáceres JF. DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans. Nucleic Acids Research. 41: 8319-31. PMID 23828042 DOI: 10.1093/nar/gkt585  0.48
2013 Choudhury NR, de Lima Alves F, de Andrés-Aguayo L, Graf T, Cáceres JF, Rappsilber J, Michlewski G. Tissue-specific control of brain-enriched miR-7 biogenesis. Genes & Development. 27: 24-38. PMID 23307866 DOI: 10.1101/gad.199190.112  0.48
2012 Macias S, Plass M, Stajuda A, Michlewski G, Eyras E, Cáceres JF. DGCR8 HITS-CLIP reveals novel functions for the Microprocessor. Nature Structural & Molecular Biology. 19: 760-6. PMID 22796965 DOI: 10.1038/nsmb.2344  0.64
2011 Michlewski G, Guil S, Cáceres JF. Stimulation of pri-miR-18a Processing by hnRNP A1. Advances in Experimental Medicine and Biology. 700: 28-35. PMID 21755470 DOI: 10.1007/978-1-4419-7823-3_3  0.64
2011 Anastasaki C, Longman D, Capper A, Patton EE, Cáceres JF. Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish. Nucleic Acids Research. 39: 3686-94. PMID 21227923 DOI: 10.1093/nar/gkq1319  0.64
2010 Michlewski G, Guil S, Cáceres JF. Stimulation of pri-miR-18a processing by hnRNP A1. Advances in Experimental Medicine and Biology. 700: 28-35. PMID 21627027 DOI: 10.1007/978-1-4419-7823-3_3  0.64
2010 Michlewski G, Cáceres JF. Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Nature Structural & Molecular Biology. 17: 1011-8. PMID 20639884 DOI: 10.1038/nsmb.1874  0.64
2010 Michlewski G, Cáceres JF. RNase-assisted RNA chromatography. Rna (New York, N.Y.). 16: 1673-8. PMID 20571124 DOI: 10.1261/rna.2136010  0.64
2010 Lünse CE, Michlewski G, Hopp CS, Rentmeister A, Cáceres JF, Famulok M, Mayer G. An aptamer targeting the apical-loop domain modulates pri-miRNA processing. Angewandte Chemie (International Ed. in English). 49: 4674-7. PMID 20533473 DOI: 10.1002/anie.200906919  0.64
2009 Macias S, Michlewski G, Cáceres JF. Hormonal regulation of microRNA biogenesis. Molecular Cell. 36: 172-3. PMID 19854126 DOI: 10.1016/j.molcel.2009.10.006  0.64
2009 Heale BS, Keegan LP, McGurk L, Michlewski G, Brindle J, Stanton CM, Caceres JF, O'Connell MA. Editing independent effects of ADARs on the miRNA/siRNA pathways. The Embo Journal. 28: 3145-56. PMID 19713932 DOI: 10.1038/emboj.2009.244  0.48
2009 Biamonti G, Caceres JF. Cellular stress and RNA splicing. Trends in Biochemical Sciences. 34: 146-53. PMID 19208481 DOI: 10.1016/j.tibs.2008.11.004  0.48
2009 Long JC, Caceres JF. The SR protein family of splicing factors: master regulators of gene expression. The Biochemical Journal. 417: 15-27. PMID 19061484 DOI: 10.1042/BJ20081501  0.48
2008 Longman D, Arrisi P, Johnstone IL, Cáceres JF. Chapter 7. Nonsense-mediated mRNA decay in Caenorhabditis elegans. Methods in Enzymology. 449: 149-64. PMID 19215757 DOI: 10.1016/S0076-6879(08)02407-5  0.64
2008 Michlewski G, Guil S, Semple CA, Cáceres JF. Posttranscriptional regulation of miRNAs harboring conserved terminal loops. Molecular Cell. 32: 383-93. PMID 18995836 DOI: 10.1016/j.molcel.2008.10.013  0.64
2008 Sanford JR, Coutinho P, Hackett JA, Wang X, Ranahan W, Caceres JF. Identification of nuclear and cytoplasmic mRNA targets for the shuttling protein SF2/ASF. Plos One. 3: e3369. PMID 18841201 DOI: 10.1371/journal.pone.0003369  0.48
2008 Ellis JD, Llères D, Denegri M, Lamond AI, Cáceres JF. Spatial mapping of splicing factor complexes involved in exon and intron definition. The Journal of Cell Biology. 181: 921-34. PMID 18559666 DOI: 10.1083/jcb.200710051  0.48
2008 Michlewski G, Sanford JR, Cáceres JF. The splicing factor SF2/ASF regulates translation initiation by enhancing phosphorylation of 4E-BP1. Molecular Cell. 30: 179-89. PMID 18439897 DOI: 10.1016/j.molcel.2008.03.013  0.64
2007 Caceres JF, Misteli T. Division of labor: minor splicing in the cytoplasm. Cell. 131: 645-7. PMID 18022356 DOI: 10.1016/j.cell.2007.11.001  0.48
2007 Guil S, Cáceres JF. Stressful splicing. Molecular Cell. 28: 180-1. PMID 17964256 DOI: 10.1016/j.molcel.2007.10.004  0.64
2007 Santamaría D, Barrière C, Cerqueira A, Hunt S, Tardy C, Newton K, Cáceres JF, Dubus P, Malumbres M, Barbacid M. Cdk1 is sufficient to drive the mammalian cell cycle. Nature. 448: 811-5. PMID 17700700 DOI: 10.1038/nature06046  0.48
2007 Caceres JF, Krainer AR, Kornblihtt AR. The pathology of pre-mRNA splicing: a meeting in the Italian Alps. Workshop on pre-mRNA processing and disease. Embo Reports. 8: 730-4. PMID 17668002 DOI: 10.1038/sj.embor.7401032  0.48
2007 Fortes P, Longman D, McCracken S, Ip JY, Poot R, Mattaj IW, Cáceres JF, Blencowe BJ. Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3'-end formation. Febs Letters. 581: 3087-97. PMID 17560998 DOI: 10.1016/j.febslet.2007.05.066  0.48
2007 Guil S, Cáceres JF. The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. Nature Structural & Molecular Biology. 14: 591-6. PMID 17558416 DOI: 10.1038/nsmb1250  0.64
2007 Longman D, Plasterk RH, Johnstone IL, Cáceres JF. Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway. Genes & Development. 21: 1075-85. PMID 17437990 DOI: 10.1101/gad.417707  0.64
2006 Guil S, Long JC, Cáceres JF. hnRNP A1 relocalization to the stress granules reflects a role in the stress response. Molecular and Cellular Biology. 26: 5744-58. PMID 16847328 DOI: 10.1128/MCB.00224-06  0.48
2005 Blaustein M, Pelisch F, Tanos T, Muñoz MJ, Wengier D, Quadrana L, Sanford JR, Muschietti JP, Kornblihtt AR, Cáceres JF, Coso OA, Srebrow A. Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT. Nature Structural & Molecular Biology. 12: 1037-44. PMID 16299516 DOI: 10.1038/nsmb1020  0.48
2005 Sanford JR, Ellis JD, Cazalla D, Cáceres JF. Reversible phosphorylation differentially affects nuclear and cytoplasmic functions of splicing factor 2/alternative splicing factor. Proceedings of the National Academy of Sciences of the United States of America. 102: 15042-7. PMID 16210245 DOI: 10.1073/pnas.0507827102  0.48
2005 McCracken S, Longman D, Marcon E, Moens P, Downey M, Nickerson JA, Jessberger R, Wilde A, Caceres JF, Emili A, Blencowe BJ. Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin. The Journal of Biological Chemistry. 280: 42227-36. PMID 16159877 DOI: 10.1074/jbc.M507410200  0.48
2005 Sanford JR, Ellis J, Cáceres JF. Multiple roles of arginine/serine-rich splicing factors in RNA processing. Biochemical Society Transactions. 33: 443-6. PMID 15916537 DOI: 10.1042/BST0330443  0.64
2005 Cazalla D, Sanford JR, Cáceres JF. A rapid and efficient protocol to purify biologically active recombinant proteins from mammalian cells. Protein Expression and Purification. 42: 54-8. PMID 15878828 DOI: 10.1016/j.pep.2005.03.035  0.64
2005 Cazalla D, Newton K, Cáceres JF. A novel SR-related protein is required for the second step of Pre-mRNA splicing. Molecular and Cellular Biology. 25: 2969-80. PMID 15798186 DOI: 10.1128/MCB.25.8.2969-2980.2005  0.64
2005 Allemand E, Guil S, Myers M, Moscat J, Cáceres JF, Krainer AR. Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock. Proceedings of the National Academy of Sciences of the United States of America. 102: 3605-10. PMID 15738418 DOI: 10.1073/pnas.0409889102  0.48
2004 Sanford JR, Caceres JF. Pre-mRNA splicing: life at the centre of the central dogma. Journal of Cell Science. 117: 6261-3. PMID 15591240 DOI: 10.1242/jcs.01513  0.48
2004 Sanford JR, Gray NK, Beckmann K, Cáceres JF. A novel role for shuttling SR proteins in mRNA translation. Genes & Development. 18: 755-68. PMID 15082528 DOI: 10.1101/gad.286404  0.64
2004 Niksic M, Slight J, Sanford JR, Caceres JF, Hastie ND. The Wilms' tumour protein (WT1) shuttles between nucleus and cytoplasm and is present in functional polysomes. Human Molecular Genetics. 13: 463-71. PMID 14681305 DOI: 10.1093/hmg/ddh040  0.48
2003 Newton K, Petfalski E, Tollervey D, Cáceres JF. Fibrillarin is essential for early development and required for accumulation of an intron-encoded small nucleolar RNA in the mouse. Molecular and Cellular Biology. 23: 8519-27. PMID 14612397 DOI: 10.1128/MCB.23.23.8519-8527.2003  0.48
2003 McCracken S, Longman D, Johnstone IL, Cáceres JF, Blencowe BJ. An evolutionarily conserved role for SRm160 in 3'-end processing that functions independently of exon junction complex formation. The Journal of Biological Chemistry. 278: 44153-60. PMID 12944400 DOI: 10.1074/jbc.M306856200  0.48
2003 Longman D, Johnstone IL, Cáceres JF. The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans. Rna (New York, N.Y.). 9: 881-91. PMID 12810921  0.64
2003 Sanford JR, Longman D, Cáceres JF. Multiple roles of the SR protein family in splicing regulation. Progress in Molecular and Subcellular Biology. 31: 33-58. PMID 12494762  0.64
2002 Cazalla D, Zhu J, Manche L, Huber E, Krainer AR, Cáceres JF. Nuclear export and retention signals in the RS domain of SR proteins. Molecular and Cellular Biology. 22: 6871-82. PMID 12215544 DOI: 10.1128/MCB.22.19.6871-6882.2002  0.48
2002 Cáceres JF, Kornblihtt AR. Alternative splicing: multiple control mechanisms and involvement in human disease. Trends in Genetics : Tig. 18: 186-93. PMID 11932019 DOI: 10.1016/S0168-9525(01)02626-9  0.48
2001 Longman D, McGarvey T, McCracken S, Johnstone IL, Blencowe BJ, Cáceres JF. Multiple interactions between SRm160 and SR family proteins in enhancer-dependent splicing and development of C. elegans. Current Biology : Cb. 11: 1923-33. PMID 11747818 DOI: 10.1016/S0960-9822(01)00589-9  0.48
2001 Cowper AE, Cáceres JF, Mayeda A, Screaton GR. Serine-arginine (SR) protein-like factors that antagonize authentic SR proteins and regulate alternative splicing. The Journal of Biological Chemistry. 276: 48908-14. PMID 11684676 DOI: 10.1074/jbc.M103967200  0.48
2001 Sutherland HG, Mumford GK, Newton K, Ford LV, Farrall R, Dellaire G, Cáceres JF, Bickmore WA. Large-scale identification of mammalian proteins localized to nuclear sub-compartments. Human Molecular Genetics. 10: 1995-2011. PMID 11555636  0.64
2001 Allemand E, Gattoni R, Bourbon HM, Stevenin J, Cáceres JF, Soret J, Tazi J. Distinctive features of Drosophila alternative splicing factor RS domain: implication for specific phosphorylation, shuttling, and splicing activation. Molecular and Cellular Biology. 21: 1345-59. PMID 11158320 DOI: 10.1128/MCB.21.4.1345-1359.2001  0.64
2000 van Der Houven Van Oordt W, Newton K, Screaton GR, Cáceres JF. Role of SR protein modular domains in alternative splicing specificity in vivo. Nucleic Acids Research. 28: 4822-31. PMID 11121472  0.48
2000 Tollervey D, Caceres JF. RNA processing marches on. Cell. 103: 703-9. PMID 11114327  0.48
2000 Eperon IC, Makarova OV, Mayeda A, Munroe SH, Cáceres JF, Hayward DG, Krainer AR. Selection of alternative 5' splice sites: role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1. Molecular and Cellular Biology. 20: 8303-18. PMID 11046128 DOI: 10.1128/MCB.20.22.8303-8318.2000  0.48
2000 van der Houven van Oordt W, Diaz-Meco MT, Lozano J, Krainer AR, Moscat J, Cáceres JF. The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation. The Journal of Cell Biology. 149: 307-16. PMID 10769024 DOI: 10.1083/jcb.149.2.307  0.48
2000 Longman D, Johnstone IL, Cáceres JF. Functional characterization of SR and SR-related genes in Caenorhabditis elegans. The Embo Journal. 19: 1625-37. PMID 10747030 DOI: 10.1093/emboj/19.7.1625  0.64
1999 Cramer P, Cáceres JF, Cazalla D, Kadener S, Muro AF, Baralle FE, Kornblihtt AR. Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer. Molecular Cell. 4: 251-8. PMID 10488340 DOI: 10.1016/S1097-2765(00)80372-X  0.48
1998 Misteli T, Cáceres JF, Clement JQ, Krainer AR, Wilkinson MF, Spector DL. Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo. The Journal of Cell Biology. 143: 297-307. PMID 9786943 DOI: 10.1083/jcb.143.2.297  0.48
1998 Hanamura A, Cáceres JF, Mayeda A, Franza BR, Krainer AR. Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors. Rna (New York, N.Y.). 4: 430-44. PMID 9630249  0.48
1998 Cáceres JF, Screaton GR, Krainer AR. A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm. Genes & Development. 12: 55-66. PMID 9420331  0.48
1997 Cáceres JF, Misteli T, Screaton GR, Spector DL, Krainer AR. Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity. The Journal of Cell Biology. 138: 225-38. PMID 9230067 DOI: 10.1083/jcb.138.2.225  0.48
1997 Misteli T, Cáceres JF, Spector DL. The dynamics of a pre-mRNA splicing factor in living cells. Nature. 387: 523-7. PMID 9168118 DOI: 10.1038/387523a0  0.48
1996 Colwill K, Feng LL, Yeakley JM, Gish GD, Cáceres JF, Pawson T, Fu XD. SRPK1 and Clk/Sty protein kinases show distinct substrate specificities for serine/arginine-rich splicing factors. The Journal of Biological Chemistry. 271: 24569-75. PMID 8798720  0.64
1995 Screaton GR, Cáceres JF, Mayeda A, Bell MV, Plebanski M, Jackson DG, Bell JI, Krainer AR. Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. The Embo Journal. 14: 4336-49. PMID 7556075  0.48
1994 Cáceres JF, Stamm S, Helfman DM, Krainer AR. Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors. Science (New York, N.Y.). 265: 1706-9. PMID 8085156  0.48
1994 Mayeda A, Munroe SH, Cáceres JF, Krainer AR. Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins. The Embo Journal. 13: 5483-95. PMID 7957114  0.48
1993 Cáceres JF, Krainer AR. Functional analysis of pre-mRNA splicing factor SF2/ASF structural domains. The Embo Journal. 12: 4715-26. PMID 8223480  0.64
1992 Cáceres JF, McKenzie D, Thimmapaya R, Lund E, Dahlberg JE. Control of mouse U1a and U1b snRNA gene expression by differential transcription. Nucleic Acids Research. 20: 4247-54. PMID 1508717  0.48
1990 Caceres J, Glikin G, Bravo R, Weinmann R. c-fos mediated stimulation of an AP-1 DNA binding activity in undifferentiated teratocarcinoma cell lines Oncogene. 5: 59-67. PMID 2157182  0.48
1989 Cáceres JF, Blangy D, Glikin GC. Requirement of DNA topoisomerases for in vitro chromatin assembly by 3T6 mouse cell extracts. European Journal of Biochemistry / Febs. 181: 531-7. PMID 2540977  0.64
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